thyroxine has been researched along with Gastrointestinal Stromal Tumors in 4 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Gastrointestinal Stromal Tumors: All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib." | 6.71 | Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005) |
| "Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib." | 2.71 | Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez López, G | 1 |
| Carrasco De La Fuente, M | 1 |
| Menacho Román, M | 1 |
| González Albarrán, O | 1 |
| Cano Megías, M | 1 |
| Kappers, MH | 1 |
| van Esch, JH | 1 |
| Smedts, FM | 1 |
| de Krijger, RR | 1 |
| Eechoute, K | 1 |
| Mathijssen, RH | 1 |
| Sleijfer, S | 1 |
| Leijten, F | 1 |
| Danser, AH | 1 |
| van den Meiracker, AH | 1 |
| Visser, TJ | 1 |
| de Groot, JW | 1 |
| Zonnenberg, BA | 1 |
| Plukker, JT | 1 |
| van Der Graaf, WT | 1 |
| Links, TP | 1 |
| Cholongitas, E | 1 |
| Pipili, C | 1 |
| Katsogridakis, K | 1 |
| Relos, K | 1 |
| Dasenaki, M | 1 |
1 trial available for thyroxine and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
Imatinib induces hypothyroidism in patients receiving levothyroxine.
Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Carcinoma, Medullary; Drug Synergism; Female; Gastro | 2005 |
3 other studies available for thyroxine and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
[Management of hypothyroidism secondary to tyrosine kinase inhibitors: description of treatment in three distinct clinical settings].
Topics: Adult; Benzamides; Benzenesulfonates; Carcinoma, Renal Cell; Choristoma; Female; Gastrointestinal St | 2011 |
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression.
Topics: Aged; Animals; Antineoplastic Agents; Body Weight; Capillaries; Carcinoma, Renal Cell; Female; Gastr | 2011 |
Dermatitis after suspected imatinib-levothyroxine interaction in a patient with gastrointestinal stromal tumor.
Topics: Aged; Antineoplastic Agents; Benzamides; Drug Eruptions; Gastrointestinal Stromal Tumors; Humans; Im | 2008 |