thyroxine has been researched along with Froehlich's Syndrome in 25 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the influence of estriol administration on the hypothalamus-pituitary function and gonadotropins secretion in patients affected by functional hypothalamic amenorrhea (FHA)." | 9.16 | Estriol administration modulates luteinizing hormone secretion in women with functional hypothalamic amenorrhea. ( Chierchia, E; Genazzani, AD; Meczekalski, B; Podfigurna-Stopa, A; Rattighieri, E; Ricchieri, F; Santagni, S; Simoncini, T, 2012) |
| "To further characterize hypothyroidemia with decreased serum concentrations of total triiodothyronine and total T4 in women with functional hypothalamic amenorrhea." | 7.69 | Altered binding of serum thyroid hormone to thyroxine-binding globulin in women with functional hypothalamic amenorrhea. ( Dominguez, CE; Laughlin, GA; Nelson, JC; Yen, SS, 1997) |
| "To evaluate the influence of estriol administration on the hypothalamus-pituitary function and gonadotropins secretion in patients affected by functional hypothalamic amenorrhea (FHA)." | 5.16 | Estriol administration modulates luteinizing hormone secretion in women with functional hypothalamic amenorrhea. ( Chierchia, E; Genazzani, AD; Meczekalski, B; Podfigurna-Stopa, A; Rattighieri, E; Ricchieri, F; Santagni, S; Simoncini, T, 2012) |
| "Echocardiography and serum thyroid hormones were assessed in overt primary (n=20) and central (n=10) hypothyroidism, subclinical primary hypothyroidism (n=10), hypothalamic-pituitary disease with normal free thyroxine (FT(4); n=25), and controls (n=28)." | 5.16 | Diagnosis of subclinical central hypothyroidism in patients with hypothalamic-pituitary disease by Doppler echocardiography. ( Abucham, J; Doin, FC; Martins, MR; Moisés, VA; Rosa-Borges, M, 2012) |
| "To further characterize hypothyroidemia with decreased serum concentrations of total triiodothyronine and total T4 in women with functional hypothalamic amenorrhea." | 3.69 | Altered binding of serum thyroid hormone to thyroxine-binding globulin in women with functional hypothalamic amenorrhea. ( Dominguez, CE; Laughlin, GA; Nelson, JC; Yen, SS, 1997) |
| " On the diagnosis of hypothalamic hypothyroidism, she was treated with levothyroxine sodium." | 3.68 | Portal-systemic encephalopathy and hypothalamic hypothyroidism: effect of thyroid hormone on ammonia metabolism. ( Hitoshi, S; Sakuta, M; Terao, Y, 1993) |
| " We report what we believe is a new association following initiation of thyroxine (T4) replacement in hypothalamic hypothyroidism, as well as another occurrence following T4 replacement in primary hypothyroidism." | 3.67 | Pseudotumor cerebri following treatment of hypothalamic and primary hypothyroidism. ( Huseman, CA; Torkelson, RD, 1984) |
| " Individualized management and accurate hormone replacement dosage for postoperative childhood-onset CP patients are of great importance." | 1.91 | Postoperative hypothalamic-pituitary dysfunction and long-term hormone replacement in patients with childhood-onset craniopharyngioma. ( Bai, RN; Chen, J; Deng, Y; Fan, K; Ge, M; Gong, J; Li, S; Miao, Y; Peng, X; Wei, Y; Wu, D; Wu, Q; Zhao, C, 2023) |
| " The dangers associated with changing to a preparation with different bioavailability are summarized, noting the particular danger of giving a more active preparation to a patient receiving TSH-suppressive doses of levothyroxine." | 1.33 | New questions regarding bioequivalence of levothyroxine preparations: a clinician's response. ( Green, WL, 2005) |
| "Hypogonadism was the result of complete hypothalamic-pituitary deficiency." | 1.29 | Hypothalamic-pituitary deficiency after Weil's syndrome: a case report. ( Kalogeropoulos, A; Panidis, D; Rousso, D; Skiadopoulos, S; Vavilis, D, 1994) |
| "We conclude that central hypothyroidism is characterized by a deficient nocturnal surge of TSH, and accordingly, we suggest that evaluation of the circadian pattern of TSH may be a useful adjunct in making the diagnosis of hypothyroidism in patients with diseases involving the pituitary or hypothalamus." | 1.27 | Deficient nocturnal surge of thyrotropin in central hypothyroidism. ( Caron, PJ; Nieman, LK; Nisula, BC; Rose, SR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (28.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miao, Y | 1 |
| Fan, K | 1 |
| Peng, X | 1 |
| Li, S | 1 |
| Chen, J | 1 |
| Bai, RN | 1 |
| Wei, Y | 1 |
| Deng, Y | 1 |
| Zhao, C | 1 |
| Wu, Q | 1 |
| Ge, M | 1 |
| Gong, J | 1 |
| Wu, D | 1 |
| Michopoulos, V | 1 |
| Mancini, F | 1 |
| Loucks, TL | 1 |
| Berga, SL | 1 |
| Arkader, R | 1 |
| Takeuchi, CA | 1 |
| Bjørn, AM | 1 |
| Bojesen, A | 1 |
| Gravholt, CH | 1 |
| Laurberg, P | 1 |
| Genazzani, AD | 1 |
| Meczekalski, B | 1 |
| Podfigurna-Stopa, A | 1 |
| Santagni, S | 1 |
| Rattighieri, E | 1 |
| Ricchieri, F | 1 |
| Chierchia, E | 1 |
| Simoncini, T | 1 |
| Doin, FC | 1 |
| Rosa-Borges, M | 1 |
| Martins, MR | 1 |
| Moisés, VA | 1 |
| Abucham, J | 1 |
| Green, WL | 1 |
| Shibusawa, N | 1 |
| Yamada, M | 1 |
| Crofton, PM | 1 |
| Tepper, LA | 1 |
| Kelnar, CJ | 1 |
| Huseman, CA | 1 |
| Torkelson, RD | 1 |
| Kupari, M | 1 |
| Pelkonen, R | 1 |
| Valtonen, V | 1 |
| Panidis, D | 1 |
| Rousso, D | 1 |
| Skiadopoulos, S | 1 |
| Vavilis, D | 1 |
| Kalogeropoulos, A | 1 |
| Hileman, SM | 1 |
| Kuehl, DE | 1 |
| Jackson, GL | 1 |
| Hitoshi, S | 1 |
| Terao, Y | 1 |
| Sakuta, M | 1 |
| Lee, KO | 1 |
| Persani, L | 1 |
| Tan, M | 1 |
| Sundram, FX | 1 |
| Beck-Peccoz, P | 1 |
| LoPresti, JS | 1 |
| Dominguez, CE | 1 |
| Laughlin, GA | 1 |
| Nelson, JC | 1 |
| Yen, SS | 1 |
| Suter, SN | 1 |
| Kaplan, SL | 1 |
| Aubert, ML | 1 |
| Grumbach, MM | 1 |
| Adriaanse, R | 1 |
| Romijn, JA | 1 |
| Endert, E | 1 |
| Wiersinga, WM | 1 |
| Yamamoto, T | 1 |
| Kimura, T | 1 |
| Ota, K | 1 |
| Shoji, M | 1 |
| Inoue, M | 1 |
| Sato, K | 1 |
| Ohta, M | 1 |
| Saito, T | 1 |
| Abe, K | 1 |
| Yoshinaga, K | 1 |
| Rose, SR | 2 |
| Manasco, PK | 1 |
| Pearce, S | 1 |
| Nisula, BC | 2 |
| Gharib, H | 1 |
| Abboud, CF | 1 |
| Jurney, TH | 1 |
| Wartofsky, L | 1 |
| Caron, PJ | 1 |
| Nieman, LK | 1 |
| Webster, B | 1 |
| Bain, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pathogenesis of Functional Hypothalamic Amenorrhea[NCT01674426] | 17 participants (Actual) | Interventional | 1997-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thyroxine and Froehlich's Syndrome
| Article | Year |
|---|---|
[Hypothalamic hypothyroidism].
Topics: Diagnosis, Differential; Humans; Hypothalamic Diseases; Hypothyroidism; Prognosis; Thyrotropin-Relea | 2006 |
Laboratory tests for thyroid disorders.
Topics: Autoantibodies; Clinical Laboratory Techniques; Female; Humans; Hypothalamic Diseases; Iodide Peroxi | 1996 |
4 trials available for thyroxine and Froehlich's Syndrome
| Article | Year |
|---|---|
Neuroendocrine recovery initiated by cognitive behavioral therapy in women with functional hypothalamic amenorrhea: a randomized, controlled trial.
Topics: Academic Medical Centers; Amenorrhea; Analysis of Variance; Cognitive Behavioral Therapy; Female; Hu | 2013 |
Estriol administration modulates luteinizing hormone secretion in women with functional hypothalamic amenorrhea.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Amenorrhea; Analysis of Variance; Androstenedione; Estradiol; E | 2012 |
Diagnosis of subclinical central hypothyroidism in patients with hypothalamic-pituitary disease by Doppler echocardiography.
Topics: Adult; Asymptomatic Diseases; Cross-Sectional Studies; Diagnostic Techniques, Endocrine; Echocardiog | 2012 |
Antidiuretic effect and complications of chlorpropamide therapy in diabetes insipidus.
Topics: Adolescent; Adult; Chlorpropamide; Clinical Trials as Topic; Craniopharyngioma; Diabetes Insipidus; | 1970 |
19 other studies available for thyroxine and Froehlich's Syndrome
| Article | Year |
|---|---|
Postoperative hypothalamic-pituitary dysfunction and long-term hormone replacement in patients with childhood-onset craniopharyngioma.
Topics: Child; Craniopharyngioma; Deamino Arginine Vasopressin; Hormone Replacement Therapy; Humans; Hydroco | 2023 |
Shapiro syndrome with hypothalamic hypothyroidism.
Topics: Agenesis of Corpus Callosum; Child; Cyproheptadine; Humans; Hyperhidrosis; Hypothalamic Diseases; Hy | 2008 |
Hypothyroidism secondary to hypothalamic-pituitary dysfunction may be part of the phenotype in klinefelter syndrome: a case-control study.
Topics: Adult; Autoantibodies; Case-Control Studies; Hormone Replacement Therapy; Humans; Hypothalamic Disea | 2009 |
New questions regarding bioequivalence of levothyroxine preparations: a clinician's response.
Topics: Area Under Curve; Atrial Fibrillation; Biological Availability; Biopharmaceutics; Chemistry, Pharmac | 2005 |
An evaluation of the thyrotrophin-releasing hormone stimulation test in paediatric clinical practice.
Topics: Adolescent; Child; Child, Preschool; Diagnosis, Differential; Diagnostic Techniques, Endocrine; Fema | 2008 |
Pseudotumor cerebri following treatment of hypothalamic and primary hypothyroidism.
Topics: Adolescent; Empty Sella Syndrome; Female; Fundus Oculi; Humans; Hypothalamic Diseases; Hypothyroidis | 1984 |
Post-encephalitic hypothalamic-pituitary insufficiency.
Topics: Adult; Diabetes Insipidus; Encephalitis, Arbovirus; Female; Growth Hormone; Herpes Simplex; Humans; | 1980 |
Hypothalamic-pituitary deficiency after Weil's syndrome: a case report.
Topics: Adult; Chorionic Gonadotropin; Clomiphene; Follicle Stimulating Hormone; Gonadotropin-Releasing Horm | 1994 |
Effect of anterior hypothalamic area lesions on photoperiod-induced shifts in reproductive activity of the ewe.
Topics: Animals; Female; Hypothalamic Diseases; Hypothalamus, Anterior; Melatonin; Photoperiod; Progesterone | 1994 |
Portal-systemic encephalopathy and hypothalamic hypothyroidism: effect of thyroid hormone on ammonia metabolism.
Topics: Ammonia; Euthyroid Sick Syndromes; Female; Hepatic Encephalopathy; Humans; Hypothalamic Diseases; Hy | 1993 |
Thyrotropin with decreased biological activity, a delayed consequence of cranial irradiation for nasopharyngeal carcinoma.
Topics: Adult; Aged; Humans; Hypothalamic Diseases; Hypothyroidism; Kinetics; Middle Aged; Nasopharyngeal Ne | 1995 |
Altered binding of serum thyroid hormone to thyroxine-binding globulin in women with functional hypothalamic amenorrhea.
Topics: Adult; Amenorrhea; Cohort Studies; Electrophoresis; Female; Follicular Phase; Humans; Hypothalamic D | 1997 |
Plasma prolactin and thyrotropin and the response to thyrotropin-releasing factor in children with primary and hypothalamic hypothyroidism.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Hyperthyroidism; Hypopituitarism; Hypoth | 1978 |
The nocturnal thyroid-stimulating hormone surge is absent in overt, present in mild primary and equivocal in central hypothyroidism.
Topics: Circadian Rhythm; Humans; Hypothalamic Diseases; Hypothyroidism; Pituitary Diseases; Thyrotropin; Th | 1992 |
Cyclical edema in a patient with hypothalamic disorders and chronic glomerulonephritis: arginine vasopressin-dependent atrial natriuretic hormone release.
Topics: Adult; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Body Weight; Chronic Disease; E | 1991 |
Hypothyroidism and deficiency of the nocturnal thyrotropin surge in children with hypothalamic-pituitary disorders.
Topics: Adolescent; Child; Child, Preschool; Circadian Rhythm; Humans; Hypothalamic Diseases; Hypothyroidism | 1990 |
Primary idiopathic hypothalamic hypothyroidism. Report of four cases.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hypothalamic Diseases; Hypothyroidism; Male; Middle | 1987 |
Thyrotropin-releasing hormone tests in an outpatient clinic.
Topics: Adolescent; Adult; Aged; Child; Female; Graves Disease; Humans; Hyperthyroidism; Hypothalamic Diseas | 1985 |
Deficient nocturnal surge of thyrotropin in central hypothyroidism.
Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Hypothalamic Diseases; Hypothyroidism; Male; Mi | 1986 |