thyroxine has been researched along with Fractures, Bone in 40 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Fractures, Bone: Breaks in bones.
Excerpt | Relevance | Reference |
---|---|---|
"To evaluate the association between fracture risk and levothyroxine use in elderly women with hypothyroidism, according to previous osteoporosis history." | 7.80 | Levothyroxine dose and fracture risk according to the osteoporosis status in elderly women. ( Choi, NK; Kim, JY; Ko, YJ; Lee, J; Park, BJ; Song, HJ, 2014) |
"Studies on the effect of exogenous subclinical thyrotoxicosis on bone mineral density (BMD) in male patients treated with suppressive doses of levothyroxine for differentiated thyroid carcinoma (DTC) are not conclusive." | 7.76 | Bone mineral density and bone fracture in male patients receiving long-term suppressive levothyroxine treatment for differentiated thyroid carcinoma. ( Aguilera, E; Colomé, E; Holgado, S; Mateo, L; Reverter, JL; Sanmartí, A; Soldevila, B, 2010) |
"The purpose of this study was to assess alterations in fracture risk in patients with hyper- and hypothyroidism, and the effects of antithyroid drugs and levothyroxine on fracture risk." | 7.73 | Influence of hyper- and hypothyroidism, and the effects of treatment with antithyroid drugs and levothyroxine on fracture risk. ( Mosekilde, L; Rejnmark, L; Vestergaard, P, 2005) |
" Established thyrotoxicosis has long been recognised as a cause of high bone turnover osteoporosis and fracture but more recent studies have suggested that subclinical hyperthyroidism and long-term suppressive doses of thyroxine (T4) may also result in decreased bone mineral density (BMD) and an increased risk of fragility fracture, particularly in postmenopausal women." | 4.88 | The skeletal consequences of thyrotoxicosis. ( Bassett, JH; Brassill, MJ; Nicholls, JJ; Williams, GR, 2012) |
"Subclinical hyperthyroidism is defined by low or undetectable serum thyroid-stimulating hormone levels, with normal free thyroxine and total or free triiodothyronine levels." | 4.87 | Update on subclinical hyperthyroidism. ( Braunstein, GD; Donangelo, I, 2011) |
"Compared to patients only taking l-thyroxine, those using liothyronine had no increased risk of cardiovascular disease [hazard ratio (HR) 1·04; 95% CI 0·70-1·54], atrial fibrillation (HR 0·91: 0·47-1·75), or fractures (HR 0·79: 0·49-1·27) after adjusting for age." | 3.83 | Liothyronine use in a 17 year observational population-based study - the tears study. ( Donnelly, LA; Leese, GP; Soto-Pedre, E, 2016) |
"To evaluate the association between fracture risk and levothyroxine use in elderly women with hypothyroidism, according to previous osteoporosis history." | 3.80 | Levothyroxine dose and fracture risk according to the osteoporosis status in elderly women. ( Choi, NK; Kim, JY; Ko, YJ; Lee, J; Park, BJ; Song, HJ, 2014) |
"Studies on the effect of exogenous subclinical thyrotoxicosis on bone mineral density (BMD) in male patients treated with suppressive doses of levothyroxine for differentiated thyroid carcinoma (DTC) are not conclusive." | 3.76 | Bone mineral density and bone fracture in male patients receiving long-term suppressive levothyroxine treatment for differentiated thyroid carcinoma. ( Aguilera, E; Colomé, E; Holgado, S; Mateo, L; Reverter, JL; Sanmartí, A; Soldevila, B, 2010) |
"The purpose of this study was to assess alterations in fracture risk in patients with hyper- and hypothyroidism, and the effects of antithyroid drugs and levothyroxine on fracture risk." | 3.73 | Influence of hyper- and hypothyroidism, and the effects of treatment with antithyroid drugs and levothyroxine on fracture risk. ( Mosekilde, L; Rejnmark, L; Vestergaard, P, 2005) |
"Pain intensity was graded according to 4-score scale, atraumatic fractures in the past were recorded, mineral bone density (MBD) was studied, TTH and T4 levels and biochemical indices of calcium-phosphorus and bone metabolism were studied, thyroid volume was calculated by J." | 3.73 | [Features of osteopenic syndrome in diffuse toxic goiter]. ( Davydova, LI; Nekrasova, MR; Suplotova, LA, 2005) |
"A self-administered questionnaire was issued to 628 patients with primary idiopathic levothyroxine-substituted hypothyroidism." | 3.70 | Fractures in patients with primary idiopathic hypothyroidism. ( Hoeck, HC; Laurberg, P; Mosekilde, L; Nielsen, HK; Rejnmark, L; Rungby, J; Vestergaard, P; Weeke, J, 2000) |
"Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering from chronic debilitating diseases." | 2.46 | Drug-induced osteoporosis: mechanisms and clinical implications. ( Canalis, E; Giustina, A; Mazziotti, G, 2010) |
"In children with joint hypermobility grade II there was a higher incidence of dentofacial anomalies (χ2 = 6." | 1.56 | ENDOCRINE REGULATION OF ERYTHROID LINEAGE OF HEMATOPOIESIS IN CHILDREN LIVING UNDER A LOW-DOSE RADIATION EXPOSURE AFTER THE CHORNOBYL NPP ACCIDENT. ( Bebeshko, VG; Boyarska, OY; Bruslova, KM; Chernysh, TO; Gonchar, LO; Lyashenko, LO; Pismenniy, VD; Trychlib, IV; Tsvyetkova, NM; Vasylenko, VV; Yaroshenko, ZS, 2020) |
" We aimed to investigate fracture incidence among post-thyroidectomy thyroid cancer patients compared with a matched comparison group, and explore the association between levothyroxine dosage and fracture risk." | 1.48 | J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study. ( Lim, H; Park, Y; Shin, DW; Song, SO; Suh, B; Yun, JM, 2018) |
"The incidence of cerebral infarction is increased in patients with NFPA irrespective of GHRT." | 1.48 | Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement ( Bengtsson, O; Bryngelsson, IL; Hammarstrand, C; Johannsson, G; Olsson, DS; Ragnarsson, O, 2018) |
"Among adults aged 70 or more, current levothyroxine treatment was associated with a significantly increased risk of fracture, with a strong dose-response relation." | 1.37 | Levothyroxine dose and risk of fractures in older adults: nested case-control study. ( Anderson, GM; Austin, PC; Camacho, X; Fischer, HD; Lipscombe, LL; Rochon, PA; Turner, MR, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (22.50) | 18.7374 |
1990's | 3 (7.50) | 18.2507 |
2000's | 6 (15.00) | 29.6817 |
2010's | 19 (47.50) | 24.3611 |
2020's | 3 (7.50) | 2.80 |
Authors | Studies |
---|---|
Daya, NR | 1 |
Fretz, A | 1 |
Martin, SS | 1 |
Lutsey, PL | 1 |
Echouffo-Tcheugui, JB | 1 |
Selvin, E | 1 |
Juraschek, SP | 1 |
Sheng, N | 1 |
Xing, F | 1 |
Wang, J | 1 |
Duan, X | 1 |
Xiang, Z | 1 |
Thayakaran, R | 1 |
Adderley, NJ | 1 |
Sainsbury, C | 1 |
Torlinska, B | 1 |
Boelaert, K | 1 |
Šumilo, D | 1 |
Price, M | 1 |
Thomas, GN | 1 |
Toulis, KA | 1 |
Nirantharakumar, K | 1 |
Bebeshko, VG | 2 |
Bruslova, KM | 2 |
Volodina, TT | 1 |
Lyashenko, LO | 2 |
Tsvetkova, NM | 1 |
Trychlib, IV | 2 |
Chernysh, TO | 2 |
Boyarskiy, VG | 1 |
Gonchar, LO | 2 |
Kavardakova, NV | 1 |
Boyarska, OY | 1 |
Tsvyetkova, NM | 1 |
Pismenniy, VD | 1 |
Yaroshenko, ZS | 1 |
Vasylenko, VV | 1 |
Aubert, CE | 1 |
Floriani, C | 1 |
Bauer, DC | 1 |
da Costa, BR | 1 |
Segna, D | 1 |
Blum, MR | 1 |
Collet, TH | 1 |
Fink, HA | 1 |
Cappola, AR | 1 |
Syrogiannouli, L | 1 |
Peeters, RP | 2 |
Åsvold, BO | 1 |
den Elzen, WPJ | 1 |
Luben, RN | 1 |
Bremner, AP | 1 |
Gogakos, A | 1 |
Eastell, R | 2 |
Kearney, PM | 1 |
Hoff, M | 1 |
Le Blanc, E | 1 |
Ceresini, G | 1 |
Rivadeneira, F | 2 |
Uitterlinden, AG | 2 |
Khaw, KT | 1 |
Langhammer, A | 1 |
Stott, DJ | 1 |
Westendorp, RGJ | 1 |
Ferrucci, L | 1 |
Williams, GR | 3 |
Gussekloo, J | 1 |
Walsh, JP | 1 |
Aujesky, D | 1 |
Rodondi, N | 1 |
Shin, DW | 1 |
Suh, B | 1 |
Lim, H | 1 |
Yun, JM | 1 |
Song, SO | 1 |
Park, Y | 1 |
Hammarstrand, C | 1 |
Ragnarsson, O | 1 |
Bengtsson, O | 1 |
Bryngelsson, IL | 1 |
Johannsson, G | 1 |
Olsson, DS | 1 |
Ko, YJ | 1 |
Kim, JY | 2 |
Lee, J | 1 |
Song, HJ | 1 |
Choi, NK | 1 |
Park, BJ | 1 |
Onigata, K | 1 |
Leese, GP | 4 |
Soto-Pedre, E | 1 |
Donnelly, LA | 1 |
Flynn, RW | 1 |
Bonellie, SR | 1 |
Jung, RT | 2 |
MacDonald, TM | 1 |
Morris, AD | 1 |
Heumüller, R | 1 |
Kretschmer, I | 1 |
Döhler, N | 1 |
Wittich, R | 1 |
Menzen, M | 1 |
Homann, J | 1 |
Jaehde, U | 1 |
Murphy, E | 1 |
Glüer, CC | 1 |
Reid, DM | 1 |
Felsenberg, D | 1 |
Roux, C | 1 |
Mazziotti, G | 1 |
Canalis, E | 1 |
Giustina, A | 1 |
Reverter, JL | 1 |
Colomé, E | 1 |
Holgado, S | 1 |
Aguilera, E | 1 |
Soldevila, B | 1 |
Mateo, L | 1 |
Sanmartí, A | 1 |
Bours, SP | 1 |
van Geel, TA | 1 |
Geusens, PP | 1 |
Janssen, MJ | 1 |
Janzing, HM | 1 |
Hoffland, GA | 1 |
Willems, PC | 1 |
van den Bergh, JP | 1 |
Donangelo, I | 1 |
Braunstein, GD | 1 |
Flynn, RV | 1 |
Turner, MR | 1 |
Camacho, X | 1 |
Fischer, HD | 1 |
Austin, PC | 1 |
Anderson, GM | 1 |
Rochon, PA | 1 |
Lipscombe, LL | 1 |
Koch, L | 1 |
Medici, M | 1 |
van der Deure, WM | 1 |
Hofman, A | 1 |
van Meurs, JB | 1 |
Styrkársdottir, U | 1 |
van Duijn, CM | 1 |
Spector, T | 1 |
Kiel, DP | 1 |
Visser, TJ | 1 |
Nicholls, JJ | 1 |
Brassill, MJ | 1 |
Bassett, JH | 1 |
FONTAINE, R | 3 |
MANDEL, P | 3 |
WIEST, E | 3 |
SINGH, RH | 1 |
UDUPA, KN | 2 |
MATHIES, JC | 1 |
PALM, L | 1 |
GAEBLER, OH | 1 |
GHEVALLIER, A | 1 |
KLEIN, M | 1 |
GRIES, A | 1 |
VOGELEISEN, A | 1 |
Geoghegan, JM | 1 |
Clark, DI | 1 |
Bainbridge, LC | 1 |
Smith, C | 1 |
Hubbard, R | 1 |
Vestergaard, P | 2 |
Rejnmark, L | 2 |
Mosekilde, L | 2 |
Nekrasova, MR | 1 |
Suplotova, LA | 1 |
Davydova, LI | 1 |
Wexler, JA | 1 |
Sharretts, J | 1 |
Thomas, FB | 1 |
Compston, JE | 1 |
Rosén, T | 1 |
Wilhelmsen, L | 1 |
Landin-Wilhelmsen, K | 1 |
Lappas, G | 1 |
Bengtsson, BA | 1 |
Weeke, J | 1 |
Hoeck, HC | 1 |
Nielsen, HK | 1 |
Rungby, J | 1 |
Laurberg, P | 1 |
Guthrie, C | 1 |
Waugh, N | 1 |
Browning, MC | 1 |
Krølner, B | 1 |
Fraser, SA | 1 |
Anderson, JB | 1 |
Smith, DA | 1 |
Wilson, GM | 1 |
Gupta, LP | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900] | Phase 2 | 164 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | ||
Basal Joint Arthroplasty and Carpal Tunnel Release Comparing Single Versus Double Incision. Randomized Clinical Trial[NCT04391751] | 40 participants (Actual) | Interventional | 2018-01-01 | Active, not recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
8 reviews available for thyroxine and Fractures, Bone
Article | Year |
---|---|
Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Fractures, Bone; Hip Fractures; | 2017 |
[Thyroid hormone and skeletal metabolism].
Topics: Animals; Bone and Bones; Bone Density; Bone Development; Bone Diseases, Developmental; Bone Remodeli | 2014 |
Drug-induced osteoporosis: mechanisms and clinical implications.
Topics: Androgen Antagonists; Anti-Retroviral Agents; Aromatase Inhibitors; Bone Density; Calcineurin Inhibi | 2010 |
Update on subclinical hyperthyroidism.
Topics: Adult; Age Factors; Aged; Atrial Fibrillation; Bone Density; Cognition; Cognition Disorders; Evidenc | 2011 |
Pharmacotherapy: Levothyroxine in the elderly-finding the breaking point.
Topics: Aged; Aging; Endpoint Determination; Fractures, Bone; Humans; Risk Factors; Thyroxine | 2011 |
The skeletal consequences of thyrotoxicosis.
Topics: Bone Density; Fractures, Bone; Humans; Hyperthyroidism; Hypothalamo-Hypophyseal System; Models, Biol | 2012 |
Thyroid and bone.
Topics: Animals; Bone and Bones; Bone Density; Bone Development; Bone Neoplasms; Bone Remodeling; Diphosphon | 2007 |
Lumbar spine bone mineral content by photon beam absorptiometry. Methodology and application in osteoporosis.
Topics: Aging; Female; Fractures, Bone; Humans; Hyperthyroidism; Lumbar Vertebrae; Menopause; Methods; Miner | 1985 |
32 other studies available for thyroxine and Fractures, Bone
Article | Year |
---|---|
Association Between Subclinical Thyroid Dysfunction and Fracture Risk.
Topics: Aged; Cohort Studies; Female; Fractures, Bone; Humans; Hyperthyroidism; Hypothyroidism; Male; Medica | 2022 |
T4 rather than TSH correlates with BMD among euthyroid adults.
Topics: Adult; Bone Density; Cross-Sectional Studies; Fractures, Bone; Humans; Hypothyroidism; Nutrition Sur | 2022 |
Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Fractures, Bone; Humans; Hypothyroidism; Longitudinal | 2019 |
FEATURES OF CLINICAL SYMPTOMS AND SIGNS, HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN CHILDREN WITH JOINT HYPERMOBILITY IN A LATE PERIOD UPON THE CHORNOBYL NPP ACCIDENT.
Topics: Alkaline Phosphatase; Amino Acids; Calcium; Case-Control Studies; Chernobyl Nuclear Accident; Child; | 2019 |
ENDOCRINE REGULATION OF ERYTHROID LINEAGE OF HEMATOPOIESIS IN CHILDREN LIVING UNDER A LOW-DOSE RADIATION EXPOSURE AFTER THE CHORNOBYL NPP ACCIDENT.
Topics: Adolescent; Arthralgia; Cell Lineage; Chernobyl Nuclear Accident; Child; Child, Preschool; Dental Ca | 2020 |
J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study.
Topics: Dose-Response Relationship, Drug; Female; Fractures, Bone; Humans; Incidence; Male; Middle Aged; Ost | 2018 |
Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement
Topics: Adenoma; Adult; Aged; Cerebral Infarction; Cohort Studies; Comorbidity; Diabetes Mellitus, Type 2; F | 2018 |
Levothyroxine dose and fracture risk according to the osteoporosis status in elderly women.
Topics: Aged; Aged, 80 and over; Cohort Studies; Databases, Factual; Female; Fractures, Bone; Humans; Hypoth | 2014 |
Liothyronine use in a 17 year observational population-based study - the tears study.
Topics: Antipsychotic Agents; Atrial Fibrillation; Cardiovascular Diseases; Cohort Studies; Fractures, Bone; | 2016 |
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Comorbidity; Female; Fractures, | 2010 |
[Pharmaceutical care of an osteoporosis patient with hypothyroidism].
Topics: Absorptiometry, Photon; Aged, 80 and over; Bone Density Conservation Agents; Combined Modality Thera | 2009 |
Thyroid function within the upper normal range is associated with reduced bone mineral density and an increased risk of nonvertebral fractures in healthy euthyroid postmenopausal women.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Analysis of Variance; Bone Density; Female; Fractur | 2010 |
Bone mineral density and bone fracture in male patients receiving long-term suppressive levothyroxine treatment for differentiated thyroid carcinoma.
Topics: Bone Density; Carcinoma; Fractures, Bone; Humans; Male; Thyroid Neoplasms; Thyroxine; Vitamin D | 2010 |
Contributors to secondary osteoporosis and metabolic bone diseases in patients presenting with a clinical fracture.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Bone Density; Bone Diseases, Metabolic; Calcium; Crea | 2011 |
Levothyroxine dose and fractures in older adults.
Topics: Aged; Fractures, Bone; Humans; Hypothyroidism; Risk Factors; Thyroxine | 2011 |
Levothyroxine dose and risk of fractures in older adults: nested case-control study.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Dose-Response Relationship, Drug; Female; Follow-Up S | 2011 |
A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone.
Topics: Bone and Bones; Bone Density; Fractures, Bone; Genetic Loci; Genetic Variation; Humans; Nuclear Rece | 2012 |
[Effects of different hormones: thyroxin, desoxycorticosterone and cortisone on experimental fractures in dogs].
Topics: Animals; Cortisone; Desoxycorticosterone; Dogs; Fractures, Bone; Hormones; Thyroxine | 1952 |
THE EFFECT OF CALCIUM AND ASCORBIC ACID ON HEALING OF FRACTURES IN THYROXINE TREATED ANIMALS.
Topics: Animals; Ascorbic Acid; Calcium; Fractures, Bone; Rats; Research; Thyroxine; Wound Healing | 1965 |
Effects of hypophysectomy, growth hormone, thyroxin and food intake on cathepsin activity of rat tissues.
Topics: Animals; Cathepsins; Fractures, Bone; Growth Hormone; Hormones; Human Growth Hormone; Hypophysectomy | 1951 |
[The action of thyroxin on the evolution of experimental fractures in dogs].
Topics: Animals; Biological Evolution; Dogs; Fractures, Bone; Thyroxine | 1952 |
[Anatomical, clinical, histological, and biochemical study on the action of thyroxin, desoxycorticosterone and cortisone on the development of experimental fractures in dogs].
Topics: Animals; Cortisone; Desoxycorticosterone; Dogs; Fractures, Bone; Thyroxine | 1952 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Influence of hyper- and hypothyroidism, and the effects of treatment with antithyroid drugs and levothyroxine on fracture risk.
Topics: Adult; Antithyroid Agents; Case-Control Studies; Denmark; Dose-Response Relationship, Drug; Female; | 2005 |
[Features of osteopenic syndrome in diffuse toxic goiter].
Topics: Adult; Aged; Bone Density; Bone Diseases, Metabolic; Calcium; Case-Control Studies; Densitometry; Fe | 2005 |
Arthrodesis of the subtalar joint.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Arthrodesis; Calcaneus; Female; Flatfoot; Foot Disea | 1967 |
Thyroid hormone therapy and the skeleton.
Topics: Adult; Bone Density; Drug Administration Schedule; Female; Fractures, Bone; Humans; Hypothyroidism; | 1993 |
Increased fracture frequency in adult patients with hypopituitarism and GH deficiency.
Topics: Adolescent; Adult; Aged; Female; Fractures, Bone; Human Growth Hormone; Humans; Hypopituitarism; Ins | 1997 |
Fractures in patients with primary idiopathic hypothyroidism.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Female; Fractures, Bone; Humans; | 2000 |
Morbidity in patients on L-thyroxine: a comparison of those with a normal TSH to those with a suppressed TSH.
Topics: Aged; Breast Neoplasms; Depression, Chemical; Female; Femoral Neck Fractures; Follow-Up Studies; Fra | 1992 |
Osteoporosis and fractures following thyrotoxicosis.
Topics: Age Factors; Aged; Calcium; Densitometry; Female; Fractures, Bone; Humans; Hyperthyroidism; Iodine I | 1971 |
The effect of growth hormone and thyroxine in healing of fractures.
Topics: Animals; Fractures, Bone; Growth Hormone; Rats; Thyroxine; Wound Healing | 1965 |