Page last updated: 2024-11-06

thyroxine and Fetal Macrosomia

thyroxine has been researched along with Fetal Macrosomia in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Fetal Macrosomia: A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.

Research Excerpts

ExcerptRelevanceReference
"Prepregnancy overweight/obesity (OWO) and isolated maternal hypothyroxinemia (IMH) may increase the risk of macrosomia, but little is known about their potential combined effect on macrosomia."8.02The Interactive Effect of Prepregnancy Overweight/Obesity and Isolated Maternal Hypothyroxinemia on Macrosomia. ( Fan, J; Guo, F; Liu, Y; Yang, X; Zhang, Y; Zhou, Y, 2021)
"Prepregnancy overweight/obesity (OWO) and isolated maternal hypothyroxinemia (IMH) may increase the risk of macrosomia, but little is known about their potential combined effect on macrosomia."4.02The Interactive Effect of Prepregnancy Overweight/Obesity and Isolated Maternal Hypothyroxinemia on Macrosomia. ( Fan, J; Guo, F; Liu, Y; Yang, X; Zhang, Y; Zhou, Y, 2021)
" It is unknown, however, whether the relationships between maternal thyrotropin (TSH) and free thyroxine (fT4) levels in early pregnancy and fetal growth outcomes are modified by fetal sex."3.85Early Maternal Thyroid Function During Gestation Is Associated With Fetal Growth, Particularly in Male Newborns. ( Hrudey, EJ; Twickler, MB; Vrijkotte, TG, 2017)
"Hyperthyroidism was associated with an increased risk of preterm birth (PTB, adjusted OR: 2."1.62Impact of maternal thyroid hormone in late pregnancy on adverse birth outcomes: A retrospective cohort study in China. ( Gao, Y; Wang, H; Wang, J; Yu, B; Yuan, X, 2021)
"There was a 73% less chance of gestational hypertension for thyroid autoimmune groups."1.62Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4). ( Islam, N; Kiran, Z; Sheikh, A, 2021)
"At term, foetal breech presentation and caesarean section rate were significantly higher (P = 0·006 and P = 0·026, respectively) than in the euthyroid controls."1.46First trimester isolated maternal hypothyroxinaemia: adverse maternal metabolic profile and impact on the obstetrical outcome. ( Bernard, P; Daumerie, C; Furnica, RM; Gruson, D; Lazarus, JH; Maiter, D, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Wu, W1
Zhou, Y2
Liu, Y2
Liu, C1
Ren, J1
Liu, X1
Korevaar, TIM1
Fan, J2
Nikolaou, M1
Vasilakis, IA1
Marinakis, NM1
Tilemis, FN1
Zellos, A1
Lykopoulou, E1
Traeger-Synodinos, J1
Kanaka-Gantenbein, C1
Yuan, X1
Wang, J1
Gao, Y1
Wang, H1
Yu, B1
Kiran, Z1
Sheikh, A1
Islam, N1
Guo, F1
Yang, X1
Zhang, Y1
Vrijkotte, TG1
Hrudey, EJ1
Twickler, MB1
Hou, J1
Yu, P1
Zhu, H1
Pan, H1
Li, N1
Yang, H1
Jiang, Y1
Wang, L1
Wang, B1
Wang, Y1
You, L1
Chen, S1
Furnica, RM1
Gruson, D1
Lazarus, JH1
Maiter, D1
Bernard, P1
Daumerie, C1

Reviews

2 reviews available for thyroxine and Fetal Macrosomia

ArticleYear
Hepatomegaly and fatty liver disease secondary to central hypothyroidism in combination with macrosomia as initial presentation of IGSF1 deficiency syndrome.
    Hormones (Athens, Greece), 2023, Volume: 22, Issue:3

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Macrosomia; Hepatomegaly; Humans; Immunoglobulins; I

2023
The impact of maternal hypothyroidism during pregnancy on neonatal outcomes: a systematic review and meta-analysis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:1

    Topics: Birth Weight; Female; Fetal Macrosomia; Hormone Replacement Therapy; Humans; Hypothyroidism; Infant,

2016

Other Studies

6 other studies available for thyroxine and Fetal Macrosomia

ArticleYear
Triglycerides Mediate the Relationship Between Maternal Free Thyroxine and Birth Weight: A Prospective Cohort Study from China.
    Thyroid : official journal of the American Thyroid Association, 2023, Volume: 33, Issue:5

    Topics: Birth Weight; China; Diabetes, Gestational; Female; Fetal Macrosomia; Humans; Pregnancy; Prospective

2023
Impact of maternal thyroid hormone in late pregnancy on adverse birth outcomes: A retrospective cohort study in China.
    Endocrine journal, 2021, Mar-28, Volume: 68, Issue:3

    Topics: Adult; China; Cohort Studies; Female; Fetal Macrosomia; Humans; Hyperthyroidism; Hyperthyroxinemia;

2021
Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4).
    BMC pregnancy and childbirth, 2021, Feb-15, Volume: 21, Issue:1

    Topics: Abortion, Spontaneous; Abruptio Placentae; Adult; Apgar Score; Autoantibodies; Autoimmune Diseases;

2021
The Interactive Effect of Prepregnancy Overweight/Obesity and Isolated Maternal Hypothyroxinemia on Macrosomia.
    The Journal of clinical endocrinology and metabolism, 2021, 06-16, Volume: 106, Issue:7

    Topics: Adult; Body Weight; China; Female; Fetal Macrosomia; Humans; Hypothyroidism; Infant, Newborn; Obesit

2021
Early Maternal Thyroid Function During Gestation Is Associated With Fetal Growth, Particularly in Male Newborns.
    The Journal of clinical endocrinology and metabolism, 2017, 03-01, Volume: 102, Issue:3

    Topics: Adult; Asymptomatic Diseases; Autoantibodies; Birth Weight; Cohort Studies; Female; Fetal Macrosomia

2017
First trimester isolated maternal hypothyroxinaemia: adverse maternal metabolic profile and impact on the obstetrical outcome.
    Clinical endocrinology, 2017, Volume: 86, Issue:4

    Topics: Adult; Body Mass Index; Breech Presentation; Cesarean Section; Female; Fetal Macrosomia; Humans; Mot

2017