thyroxine has been researched along with Fetal Growth Retardation in 35 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Fetal Growth Retardation: Failure of a FETUS to attain expected GROWTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Feto-placental growth, tissue glycogen stores and glucose levels in sera and amniotic fluid were determined in rat dams partially thyroidectomized (TX) before pregnancy and in euthyroid controls." | 7.72 | Maternal hypothyroidism in the rat influences placental and liver glycogen stores: fetal growth retardation near term is unrelated to maternal and placental glucose metabolic compromise. ( Edwards, PR; Ekins, RP; Evans, IM; Leonard, AJ; Ogilvie, LM; Pickard, MR; Sinha, AK, 2003) |
| "This study comprised 46,186 mothers for whom early pregnancy thyrotropin (TSH), free thyroxine (fT4), triiodothyronine, thyroperoxidase antibodies, hCG, as well as ultrasound crown-rump length (CRL) measurements were available." | 3.91 | Association of Maternal Thyroid Function and Thyroidal Response to Human Chorionic Gonadotropin with Early Fetal Growth. ( Fan, J; Huang, HF; Korevaar, TIM; Liu, Z; Meng, Y; Peeters, RP; Yang, S; Yang, X; Zhang, C; Zhang, Y, 2019) |
| " The fetal growth retardation, hyperleptinemia, hyperinsulinism, and cytokines distortions (transforming growth factor-beta; TGF-β, tumor necrosis factor-alpha; TNF-α, and interferon-γ; IFN-γ) were noticed at examined EDs if compared to the control group." | 3.83 | Gestational dexamethasone alters fetal neuroendocrine axis. ( Ahmed, RG, 2016) |
| " Serum levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), TSH-receptor antibody (TRAb), the duration of hyperthyroidism in pregnancy, doses of antithyroid medication, and the duration of maternal antithyroid medication throughout pregnancy were compared." | 3.80 | Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease. ( Ebina, Y; Morioka, I; Tairaku, S; Tanimura, K; Uenaka, M; Yamada, H, 2014) |
| "Among 89 hypothyroxinemic women, there was no evidence of an increased risk for fetal growth restriction, preterm birth, or low Apgar score." | 3.75 | The impact of isolated maternal hypothyroxinemia on perinatal morbidity. ( Bamforth, F; Burstyn, I; Cherry, NM; Hamm, MP; Martin, JW, 2009) |
| " Feto-placental growth, tissue glycogen stores and glucose levels in sera and amniotic fluid were determined in rat dams partially thyroidectomized (TX) before pregnancy and in euthyroid controls." | 3.72 | Maternal hypothyroidism in the rat influences placental and liver glycogen stores: fetal growth retardation near term is unrelated to maternal and placental glucose metabolic compromise. ( Edwards, PR; Ekins, RP; Evans, IM; Leonard, AJ; Ogilvie, LM; Pickard, MR; Sinha, AK, 2003) |
| " Entry criteria included: gestational age 23--30 weeks, birth weight 500--1500 g, and a serum thyroxine level obtained in the first week of life." | 3.71 | Growth-restricted premature infants are at increased risk for low thyroxine. ( Allred, EN; Leviton, A; Martin, CR; Van Marter, LJ, 2001) |
| "Severe mental retardation of the child can occur due to compromised iodine intake or thyroid disease." | 2.43 | Thyroid hormones and fetal brain development. ( Franklyn, JA; Kilby, MD; Pemberton, HN, 2005) |
| "Neonatal hyperthyroidism is usually a self-limited condition frequently associated with transplacental passage of thyroid stimulating antibodies secondary to maternal autoimmune disorders." | 1.40 | [Heart failure as early manifestation of neonatal hyperthyroidism. Case report]. ( Alvarado S, JL; Fernández V, ZA, 2014) |
| "Both had a history of intrauterine growth retardation (IUGR), but showed an appropriate growth rate after infancy (5 cm/y)." | 1.28 | Euthyroid hypothyrotropinemia in children of short stature. ( Hashimoto, H; Miyagawa, K; Sato, T; Sonoda, T, 1989) |
| "Intrauterine growth retardation is a common and potentially hazardous problem for the fetus." | 1.27 | Intrauterine growth retardation: clinical and experimental. ( Falconer, J; Owens, JA; Robinson, JS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.71) | 18.7374 |
| 1990's | 8 (22.86) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 8 (22.86) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Tosun, G | 1 |
| Kose, S | 1 |
| İşbilen Başok, B | 1 |
| Altunyurt, S | 1 |
| Zhang, Y | 1 |
| Zhang, C | 1 |
| Yang, X | 1 |
| Yang, S | 1 |
| Meng, Y | 1 |
| Liu, Z | 1 |
| Peeters, RP | 1 |
| Huang, HF | 1 |
| Korevaar, TIM | 1 |
| Fan, J | 1 |
| Sandal, G | 1 |
| Caliskan, D | 1 |
| Ormeci, AR | 1 |
| Oztas, S | 1 |
| Bisschop, PH | 1 |
| van Trotsenburg, AS | 1 |
| Uenaka, M | 1 |
| Tanimura, K | 1 |
| Tairaku, S | 1 |
| Morioka, I | 1 |
| Ebina, Y | 1 |
| Yamada, H | 1 |
| Alvarado S, JL | 1 |
| Fernández V, ZA | 1 |
| Maraka, S | 1 |
| Singh Ospina, NM | 1 |
| O'Keeffe, DT | 1 |
| Rodriguez-Gutierrez, R | 1 |
| Espinosa De Ycaza, AE | 1 |
| Wi, CI | 1 |
| Juhn, YJ | 1 |
| Coddington, CC | 1 |
| Montori, VM | 1 |
| Stan, MN | 1 |
| Ahmed, RG | 1 |
| Hamm, MP | 1 |
| Cherry, NM | 1 |
| Martin, JW | 1 |
| Bamforth, F | 1 |
| Burstyn, I | 1 |
| Roberfroid, D | 1 |
| Huybregts, L | 1 |
| Lanou, H | 1 |
| Henry, MC | 1 |
| Meda, N | 1 |
| Kolsteren F, P | 1 |
| Pickard, MR | 2 |
| Leonard, AJ | 2 |
| Ogilvie, LM | 2 |
| Edwards, PR | 2 |
| Evans, IM | 1 |
| Sinha, AK | 2 |
| Ekins, RP | 2 |
| Pemberton, HN | 1 |
| Franklyn, JA | 2 |
| Kilby, MD | 2 |
| Mahajan, SD | 1 |
| Aalinkeel, R | 1 |
| Singh, S | 1 |
| Shah, P | 1 |
| Gupta, N | 1 |
| Kochupillai, N | 1 |
| De Blasio, MJ | 1 |
| Gatford, KL | 1 |
| Robinson, JS | 2 |
| Owens, JA | 2 |
| Katricheva, LV | 1 |
| Koroliuk, IP | 1 |
| Mironov, NV | 1 |
| Kaneko, S | 2 |
| Hirano, T | 1 |
| Fukushima, Y | 2 |
| Sato, T | 3 |
| Nomura, Y | 2 |
| Shinagawa, S | 2 |
| Ogawa, Y | 1 |
| Sawa, H | 1 |
| Wozikowska, J | 1 |
| Kretowicz, W | 1 |
| Narita, S | 1 |
| Takebe, K | 1 |
| Arai, K | 1 |
| Ueda, S | 1 |
| Hannigan, JH | 1 |
| Martier, SS | 1 |
| Naber, JM | 1 |
| Kaplowitz, P | 1 |
| Webb, J | 1 |
| Serna, J | 1 |
| González-Guerrero, PR | 1 |
| Scanes, CG | 1 |
| Prati, M | 1 |
| Morreale, G | 1 |
| de Pablo, F | 1 |
| Verhaeg, J | 1 |
| Gittoes, N | 1 |
| Somerset, DA | 1 |
| Clark, PM | 1 |
| Vicens-Calvet, E | 1 |
| Seijo, G | 1 |
| Potau, N | 1 |
| de los Llanos Moreno, M | 1 |
| Carrascosa, A | 1 |
| Smith, C | 1 |
| Thomsett, M | 1 |
| Choong, C | 1 |
| Rodda, C | 1 |
| McIntyre, HD | 1 |
| Cotterill, AM | 1 |
| Müller, T | 1 |
| Rehn, M | 1 |
| Girschick, G | 1 |
| Kristen, P | 1 |
| Dietl, J | 1 |
| Martin, CR | 1 |
| Van Marter, LJ | 1 |
| Allred, EN | 1 |
| Leviton, A | 1 |
| Hiroi, H | 1 |
| Kugu, K | 1 |
| Hoshino, H | 1 |
| Kozuma, S | 1 |
| Taketani, Y | 1 |
| Mellor, DJ | 1 |
| Pearson, RA | 1 |
| Thorpe-Beeston, JG | 1 |
| Nicolaides, KH | 1 |
| Snijders, RJ | 1 |
| Felton, CV | 1 |
| Vyas, S | 1 |
| Campbell, S | 1 |
| Wrutniak, C | 1 |
| Veyre, A | 1 |
| Cabello, G | 1 |
| Hashimoto, H | 1 |
| Miyagawa, K | 1 |
| Sonoda, T | 1 |
| Falconer, J | 1 |
| Mello, MA | 1 |
| Cury, L | 1 |
| Valle, LB | 1 |
| Oliveira-Filho, RM | 1 |
| Huseman, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso[NCT00642408] | Phase 4 | 1,370 participants (Actual) | Interventional | 2003-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and Fetal Growth Retardation
| Article | Year |
|---|---|
Thyroid hormones and fetal brain development.
Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus; | 2005 |
1 trial available for thyroxine and Fetal Growth Retardation
| Article | Year |
|---|---|
Effect of maternal multiple micronutrient supplements on cord blood hormones: a randomized controlled trial.
Topics: Adult; Burkina Faso; Dietary Supplements; Female; Fetal Blood; Fetal Growth Retardation; Hormones; H | 2010 |
33 other studies available for thyroxine and Fetal Growth Retardation
| Article | Year |
|---|---|
First-trimester placental function in levothyroxine-using pregnant women: a case-control study.
Topics: Adolescent; Adult; Birth Weight; Case-Control Studies; Cesarean Section; Chorionic Gonadotropin, bet | 2020 |
Association of Maternal Thyroid Function and Thyroidal Response to Human Chorionic Gonadotropin with Early Fetal Growth.
Topics: Adult; Autoantibodies; Autoantigens; Biomarkers; Chorionic Gonadotropin; Crown-Rump Length; Female; | 2019 |
A case of ring chromosome 13 with ambiguous genitalia and primary hypothyroidism.
Topics: Abnormalities, Multiple; Chromosomes, Human, Pair 13; Clubfoot; Disorders of Sex Development; Facies | 2012 |
Images in clinical medicine. Neonatal thyrotoxicosis.
Topics: Adult; Apgar Score; Eyelids; Female; Fetal Growth Retardation; Graves Disease; Heart Rate, Fetal; Hu | 2014 |
Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease.
Topics: Abortion, Spontaneous; Adult; Antithyroid Agents; Congenital Hypothyroidism; Female; Fetal Growth Re | 2014 |
[Heart failure as early manifestation of neonatal hyperthyroidism. Case report].
Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Fetal Growth Retardation; Heart Failure; Humans; Hy | 2014 |
Effects of Levothyroxine Therapy on Pregnancy Outcomes in Women with Subclinical Hypothyroidism.
Topics: Abortion, Spontaneous; Adult; Apgar Score; Asymptomatic Diseases; Case-Control Studies; Diabetes, Ge | 2016 |
Gestational dexamethasone alters fetal neuroendocrine axis.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Endocrine Disruptors; Female; Fetal Dev | 2016 |
The impact of isolated maternal hypothyroxinemia on perinatal morbidity.
Topics: Adult; Birth Weight; Cohort Studies; Female; Fetal Growth Retardation; Humans; Hypothyroidism; Infan | 2009 |
Maternal hypothyroidism in the rat influences placental and liver glycogen stores: fetal growth retardation near term is unrelated to maternal and placental glucose metabolic compromise.
Topics: Amniotic Fluid; Analysis of Variance; Animals; Blood Glucose; Female; Fetal Blood; Fetal Growth Reta | 2003 |
Thyroid hormone dysregulation in intrauterine growth retardation associated with maternal malnutrition and/or anemia.
Topics: Anemia; Female; Fetal Blood; Fetal Growth Retardation; Fetal Nutrition Disorders; Humans; Infant, Ne | 2005 |
Placental restriction alters circulating thyroid hormone in the young lamb postnatally.
Topics: Animals; Animals, Newborn; Birth Weight; Body Composition; Body Weight; Eating; Fasting; Female; Fet | 2006 |
[The hypophyseo-thyroid system in newborn infants with fetal growth retardation and in their mothers].
Topics: Adult; Female; Fetal Growth Retardation; Growth Hormone; Humans; Infant, Newborn; Male; Maternal-Fet | 1984 |
Foetal head growth retardation due to antiepileptic drugs: with reference to GH, TSH, T4, T3 and reverse T3 concentrations.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Infant, | 1983 |
[Total thyroxine values, radiotriiodothyronine binding coefficient and free thyroxine index in newborn infants with intrauterine dystrophy syndrome and in eutrophic infants].
Topics: Female; Fetal Growth Retardation; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Thyr | 1982 |
[Fetal head growth retardation due to maternal antiepileptic drug use--with reference to GH, TSH, T4, T3 and R-T3].
Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Pregnanc | 1982 |
Independent associations among maternal alcohol consumption and infant thyroxine levels and pregnancy outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Black People; Child; Female; Fetal Alcohol Spectrum Disorders; | 1995 |
Diagnostic evaluation of short children with height 3 SD or more below the mean.
Topics: Body Height; Child; Child, Preschool; Female; Fetal Growth Retardation; Follow-Up Studies; Growth Di | 1994 |
Differential and tissue-specific regulation of (pro)insulin and insulin-like growth factor-I mRNAs and levels of thyroid hormones in growth-retarded embryos.
Topics: Animals; Chick Embryo; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Growth H | 1996 |
Circulating thyroid hormone concentrations and placental thyroid hormone receptor expression in normal human pregnancy and pregnancy complicated by intrauterine growth restriction (IUGR).
Topics: Blotting, Western; Female; Fetal Blood; Fetal Growth Retardation; Gene Expression; Gestational Age; | 1998 |
[The effectiveness of recombinant growth hormone in height deficiency due to intrauterine growth retardation].
Topics: Age Determination by Skeleton; Body Constitution; Body Weight; Child; Child, Preschool; Female; Feta | 1999 |
Maternal hypothyroxinemia influences glucose transporter expression in fetal brain and placenta.
Topics: Animals; Brain; Female; Fetal Growth Retardation; Gene Expression; Glucose Transporter Type 1; Gluco | 1999 |
Congenital thyrotoxicosis in premature infants.
Topics: Antithyroid Agents; Autoantibodies; Carbimazole; Female; Fetal Blood; Fetal Growth Retardation; Grav | 2001 |
Normalisation of a severely abnormal ductus venosus Doppler flow velocity waveform in a growth-retarded fetus with absent end-diastolic flow in the umbilical artery and congenital anomalies.
Topics: Adult; Blood Flow Velocity; Congenital Abnormalities; Diabetes Mellitus, Type 1; Diastole; Fatal Out | 2001 |
Growth-restricted premature infants are at increased risk for low thyroxine.
Topics: Adult; Birth Weight; Female; Fetal Growth Retardation; Gestational Age; Humans; Infant, Newborn; Inf | 2001 |
Hyperemesis gravidarum associated with thyrotoxicosis and a past history of an eating disorder.
Topics: Adult; Anorexia Nervosa; Antithyroid Agents; Female; Fetal Growth Retardation; Gestational Age; Huma | 2001 |
Some changes in the composition of blood during the first 24 hours after birth in normal and growth retarded lambs.
Topics: Adrenal Cortex Hormones; Animals; Blood Glucose; Female; Fetal Blood; Fetal Growth Retardation; Fruc | 1977 |
Relations between the fetal circulation and pituitary-thyroid function.
Topics: Blood Circulation; Cross-Sectional Studies; Female; Fetal Blood; Fetal Growth Retardation; Gestation | 1991 |
Unusual features of neonatal thyroid function in small-for-gestational-age lambs. Origin of plasma T4 and T3 deficiencies.
Topics: Animals; Animals, Newborn; Birth Weight; Cold Temperature; Fetal Growth Retardation; Kinetics; Radio | 1990 |
Euthyroid hypothyrotropinemia in children of short stature.
Topics: Body Weight; Child; Fetal Growth Retardation; Growth Disorders; Humans; Male; Radioimmunoassay; Stan | 1989 |
Intrauterine growth retardation: clinical and experimental.
Topics: Animals; beta-Endorphin; Endorphins; Epinephrine; Female; Fetal Growth Retardation; Fetal Heart; Fet | 1985 |
Protein-calorie malnutrition in the young pregnant rat: factors involved in fetal growth impairment.
Topics: Animals; Blood Glucose; Body Weight; Diet; Female; Fetal Growth Retardation; Insulin; Pregnancy; Pro | 1987 |
Growth enhancement by dopaminergic therapy in children with intrauterine growth retardation.
Topics: Age Determination by Skeleton; Bromocriptine; Child, Preschool; Estradiol; Female; Fetal Growth Reta | 1985 |