thyroxine has been researched along with Fetal Death in 24 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During pregnancy, the net intake of feed and water was not altered by the drug, but maternal serum thyroxine and metabolic rate were significantly elevated." | 7.68 | Diethylstilbestrol-induced perinatal lethality in the rat. I. Relationship to reduced maternal weight gain. ( Bradshaw, WS; Carter, MW; Clevenger, WR; Cornwall, GA, 1991) |
| "Pregnant A/WySn mice, 20 to 30% of whose offspring have spontaneous cleft lip, were treated with thyroxine." | 7.67 | Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain. ( Harris, MJ; Juriloff, DM, 1985) |
| "Recently, the recommended dose for iodine intake during pregnancy had been increased from 200 to 250 microg/day, because recent studies revealed that even mild-to-moderate iodine intake might affect the neuropsychological development of the child." | 4.85 | Thyroid diseases in pregnancy. ( Gärtner, R, 2009) |
| "Thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine, anti-thyroperoxidase antibody, and anti-thyroglobulin antibody at 11-13 weeks of gestation were measured in 202 singleton pregnancies that subsequently resulted in miscarriage or fetal death, and the values were compared with the results of 4318 normal pregnancies." | 3.76 | Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal death. ( Ashoor, G; Jawdat, F; Maiz, N; Nicolaides, KH; Rotas, M, 2010) |
| "To examine the relationship between maternal TSH and free thyroxine (FT(4)) concentrations in early pregnancy and the risk of miscarriage, fetal or neonatal death." | 3.75 | Higher maternal TSH levels in pregnancy are associated with increased risk for miscarriage, fetal or neonatal death. ( Benhadi, N; Bonsel, GJ; Reitsma, JB; Vrijkotte, TG; Wiersinga, WM, 2009) |
| "Chronic exposure to high doses of iodine induces thyroid dysfunction, but effects of chronic exposure to high amounts of iodine on pregnancy and fetal outcome are uncertain." | 3.73 | Developmental toxic effects of chronic exposure to high doses of iodine in the mouse. ( Guo, HL; Hao, LP; Hou, XH; Liu, LG; Sun, XF; Xu, J; Yang, XF; Yao, P, 2006) |
| "5% or 3% respectively in the wet compounded diets) on plasma thyroxine (T4), reproductive performance and kit weight gain during lactation was investigated with 3 groups of each 20 mink females." | 3.69 | Plasma thyroxine concentration in non-pregnant and lactating mink, and effect of dietary rapeseed oil in the reproduction period. ( Neil, M; Tauson, AH, 1994) |
| " During pregnancy, the net intake of feed and water was not altered by the drug, but maternal serum thyroxine and metabolic rate were significantly elevated." | 3.68 | Diethylstilbestrol-induced perinatal lethality in the rat. I. Relationship to reduced maternal weight gain. ( Bradshaw, WS; Carter, MW; Clevenger, WR; Cornwall, GA, 1991) |
| "Pregnant A/WySn mice, 20 to 30% of whose offspring have spontaneous cleft lip, were treated with thyroxine." | 3.67 | Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain. ( Harris, MJ; Juriloff, DM, 1985) |
| "Pregnancy is a complex state with many endocrinological challenges to a woman's physiology." | 2.72 | Understanding the Pathogenesis of Gestational Hypothyroidism. ( Li, X; Mallawa Kankanamalage, O; Zhou, Q, 2021) |
| "Hypothyroidism is one of the most prevalent diseases in pregnancy, but there is no consensus about its management in pregnant women." | 2.58 | Pregnancy Complications Associated With Maternal Hypothyroidism: A Systematic Review. ( Aristides, SMA; de Carvalho, HC; Demarchi, IG; Günther, LSA; Lopes, LCB; Santos, TDS; Shinohara, DR; Teixeira, JJV, 2018) |
| "Although exposure to cyanogenic plants or cyanide during pregnancy has adverse effects, no teratological study with cyanide has been conducted in goats or any other ruminant." | 1.32 | Prenatal toxicity of cyanide in goats--a model for teratological studies in ruminants. ( Górniak, SL; Soto-Blanco, B, 2004) |
| "To examine the relation between certain pregnancy complications and thyroid stimulating hormone (TSH) measurements in a cohort of pregnant women." | 1.31 | Maternal thyroid deficiency and pregnancy complications: implications for population screening. ( Allan, WC; Faix, JD; Haddow, JE; Hermos, RJ; Klein, RZ; Mitchell, ML; Palomaki, GE; Williams, JR, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (50.00) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Mallawa Kankanamalage, O | 1 |
| Zhou, Q | 1 |
| Li, X | 1 |
| Shinohara, DR | 1 |
| Santos, TDS | 1 |
| de Carvalho, HC | 1 |
| Lopes, LCB | 1 |
| Günther, LSA | 1 |
| Aristides, SMA | 1 |
| Teixeira, JJV | 1 |
| Demarchi, IG | 1 |
| Benhadi, N | 1 |
| Wiersinga, WM | 1 |
| Reitsma, JB | 1 |
| Vrijkotte, TG | 1 |
| Bonsel, GJ | 1 |
| Gärtner, R | 1 |
| Ashoor, G | 1 |
| Maiz, N | 1 |
| Rotas, M | 1 |
| Jawdat, F | 1 |
| Nicolaides, KH | 1 |
| Willemsen, H | 1 |
| Kamers, B | 1 |
| Dahlke, F | 1 |
| Han, H | 1 |
| Song, Z | 1 |
| Ansari Pirsaraei, Z | 1 |
| Tona, K | 1 |
| Decuypere, E | 1 |
| Everaert, N | 1 |
| SCHAEFER, W | 1 |
| Soto-Blanco, B | 1 |
| Górniak, SL | 1 |
| Yang, XF | 1 |
| Xu, J | 1 |
| Hou, XH | 1 |
| Guo, HL | 1 |
| Hao, LP | 1 |
| Yao, P | 1 |
| Liu, LG | 1 |
| Sun, XF | 1 |
| Christie, GA | 1 |
| Juriloff, DM | 2 |
| Stowe, HD | 1 |
| Rangel, F | 1 |
| Anstead, C | 1 |
| Goelling, B | 1 |
| Tauson, AH | 1 |
| Neil, M | 1 |
| Smyth, JA | 1 |
| Goodall, EA | 1 |
| McCoy, MA | 1 |
| Ellis, WA | 1 |
| Allan, WC | 1 |
| Haddow, JE | 1 |
| Palomaki, GE | 1 |
| Williams, JR | 1 |
| Mitchell, ML | 1 |
| Hermos, RJ | 1 |
| Faix, JD | 1 |
| Klein, RZ | 1 |
| Mujtaba, Q | 1 |
| Burrow, GN | 1 |
| Pharoah, PO | 1 |
| Ellis, SM | 1 |
| Ekins, RP | 1 |
| Williams, ES | 1 |
| Clevenger, WR | 1 |
| Cornwall, GA | 1 |
| Carter, MW | 1 |
| Bradshaw, WS | 1 |
| Blackwell, TE | 1 |
| Werdin, RE | 1 |
| Eisenmenger, MC | 1 |
| FitzSimmons, MA | 1 |
| Davis, LE | 1 |
| Leveno, KJ | 1 |
| Cunningham, FG | 1 |
| Harris, MJ | 1 |
| Chew, PC | 1 |
| Cheah, JS | 1 |
| Chan, LK | 1 |
| Tan, KL | 1 |
| van Riet, HG | 1 |
| Kal, J | 1 |
| Haspels, AA | 1 |
| Thwaites, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Are IQs Low in Offspring of Euthyroid Women With Low T4?[NCT00147433] | 5,000 participants | Observational | 2004-02-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for thyroxine and Fetal Death
| Article | Year |
|---|---|
Understanding the Pathogenesis of Gestational Hypothyroidism.
Topics: Abortion, Spontaneous; Abruptio Placentae; Animals; Estrogens; Female; Fetal Death; Humans; Hypothyr | 2021 |
Pregnancy Complications Associated With Maternal Hypothyroidism: A Systematic Review.
Topics: Abortion, Spontaneous; Female; Fetal Death; Humans; Hypothyroidism; Infant, Newborn; Maternal-Fetal | 2018 |
Thyroid diseases in pregnancy.
Topics: Brain; Female; Fetal Death; Fetal Diseases; Hormone Replacement Therapy; Humans; Intelligence Tests; | 2009 |
THE USE OF THIOURACIL DERIVATIVES DURING PREGNANCY: A REVIEW.
Topics: Basal Metabolism; Female; Fetal Death; Goiter; Humans; Hyperthyroidism; Infant; Infant Mortality; In | 1964 |
[Diabetes and pregnancy].
Topics: Abortion, Spontaneous; Congenital Abnormalities; Estrogens; Female; Fetal Death; Growth Hormone; Hum | 1974 |
1 trial available for thyroxine and Fetal Death
| Article | Year |
|---|---|
Hyperthyroidism in pregnancy: a study of 37 pregnancies in 34 patients.
Topics: Adolescent; Adult; Antithyroid Agents; Birth Weight; Female; Fetal Death; Humans; Hypertension; Hype | 1973 |
18 other studies available for thyroxine and Fetal Death
| Article | Year |
|---|---|
Higher maternal TSH levels in pregnancy are associated with increased risk for miscarriage, fetal or neonatal death.
Topics: Abortion, Spontaneous; Adult; Enzyme-Linked Immunosorbent Assay; Female; Fetal Death; Humans; Infant | 2009 |
Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal death.
Topics: Abortion, Spontaneous; Adult; Autoantibodies; Female; Fetal Death; Humans; Hypertension; Hypothyroid | 2010 |
High- and low-temperature manipulation during late incubation: effects on embryonic development, the hatching process, and metabolism in broilers.
Topics: Animals; Body Temperature; Carbon Dioxide; Chick Embryo; Cold Temperature; Egg Shell; Eggs; Embryoni | 2010 |
Prenatal toxicity of cyanide in goats--a model for teratological studies in ruminants.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Goats; Male; Models, Animal; Potassium Cy | 2004 |
Developmental toxic effects of chronic exposure to high doses of iodine in the mouse.
Topics: Animals; Colloids; Dose-Response Relationship, Drug; Eating; Female; Fetal Death; Fetal Development; | 2006 |
Influence of thyroid function on the teratogenic activity of trypan blue in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Basal Metabolism; Female; Fetal Death; Pregnancy; Pregnancy, A | 1966 |
Thyroxin-induced differential mortality of mouse embryos with cleft lip.
Topics: Animals; Cleft Lip; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Male; Mi | 1981 |
Influence of supplemental dietary vitamin A on the reproductive performance of iodine-toxic rats.
Topics: Animals; Birth Weight; Dose-Response Relationship, Drug; Female; Fetal Death; Iodine; Litter Size; P | 1980 |
Plasma thyroxine concentration in non-pregnant and lactating mink, and effect of dietary rapeseed oil in the reproduction period.
Topics: Abortion, Veterinary; Animal Feed; Animals; Animals, Newborn; Body Weight; Brassica; Fatty Acids, Mo | 1994 |
Stillbirth/perinatal weak calf syndrome: a study of calves with an abnormal thyroid gland.
Topics: Animals; Body Weight; Cattle; Cattle Diseases; Female; Fetal Death; Organ Size; Parity; Pregnancy; S | 1996 |
Maternal thyroid deficiency and pregnancy complications: implications for population screening.
Topics: Adult; Cohort Studies; Confidence Intervals; Delivery, Obstetric; Female; Fetal Death; Gestational A | 2000 |
Treatment of hyperthyroidism in pregnancy with propylthiouracil and methimazole.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Female; Fetal Blood; Fetal Death; Goiter; | 1975 |
Maternal thyroid function, iodine deficiency and fetal development.
Topics: Child, Preschool; Congenital Hypothyroidism; Female; Fetal Death; Humans; Infant; Infant Mortality; | 1976 |
Diethylstilbestrol-induced perinatal lethality in the rat. I. Relationship to reduced maternal weight gain.
Topics: Animals; Animals, Newborn; Diethylstilbestrol; Female; Fetal Death; Male; Maternal-Fetal Exchange; P | 1991 |
Goitrogenic effects in offspring of swine fed sulfadimethoxine and ormetoprim in late gestation.
Topics: Animal Feed; Animals; Animals, Newborn; Female; Fetal Death; Goiter; Pregnancy; Pyrimidines; Sulfadi | 1989 |
Hypothyroidism complicating pregnancy.
Topics: Female; Fetal Death; Humans; Hypothyroidism; Infant, Newborn; Pregnancy; Pregnancy Complications; Pr | 1988 |
Thyroxine-induced differential mortality of cleft lip mouse embryos: dose- and time-response studies of the A/WySn strain.
Topics: Animals; Cleft Lip; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Mice; Mi | 1985 |
Embryo mortality in the heat stressed ewe. 3. The role of the corpus luteum, thyroid and adrenal glands.
Topics: Adrenal Glands; Animals; Corpus Luteum; Female; Fetal Death; Hot Temperature; Hydrocortisone; Organ | 1970 |