thyroxine has been researched along with Eye Disorders in 39 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In both groups, recurrence of hyperthyroidism occurred, most commonly during the first 6 months (35% of HD and 44% of TD)." | 6.67 | Treatment of Graves' disease by carbimazole: high dose with thyroxine compared to titration dose. ( Edmonds, CJ; Tellez, M, 1994) |
| "We report the case of a 70-year-old man who developed hypothyroidism associated with TSH receptor antibodies and severe ophthalmopathy during lithium therapy." | 3.68 | Anti-eye muscle antibodies and hypothyroid Graves' disease: a case report. ( Hiromatsu, Y; Hoshino, T; Kojima, K; Kurose, S; Nakashima, A; Nonaka, K; Sato, K; Sato, M; Tanaka, K, 1992) |
| "In both groups, recurrence of hyperthyroidism occurred, most commonly during the first 6 months (35% of HD and 44% of TD)." | 2.67 | Treatment of Graves' disease by carbimazole: high dose with thyroxine compared to titration dose. ( Edmonds, CJ; Tellez, M, 1994) |
| "We have carried out a prospective study to investigate whether orbital radiotherapy combined with high dose systemic glucocorticoids is more effective than orbital radiotherapy alone for Graves' ophthalmopathy." | 2.67 | Orbital radiotherapy combined with high dose systemic glucocorticoids for Graves' ophthalmopathy is more effective than radiotherapy alone: results of a prospective randomized study. ( Bartalena, L; Bogazzi, F; Bruno-Bossio, G; Lepri, A; Marcocci, C; Pinchera, A, 1991) |
| " The study consisted of an untreated control group and five treatment groups that received continuous exposure to AP via the drinking water at dosage levels of 0." | 1.31 | A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate. ( Baker, WH; Dodd, DE; Hildebrandt, PK; Mattie, DR; Siglin, JC, 2000) |
| "Euthyroid Graves' disease is defined as Graves' ophthalmopathy without hyperthyroidism, and the thyroid-stimulating antibody (TSAb) has been known to be a good marker for diagnosis." | 1.30 | Low response of the thyroid gland to endogenous thyrotropin increased by thyrotropin-releasing hormone in patients with euthyroid Graves' disease. ( Amino, N; Fujikado, T; Hidaka, Y; Kashiwai, T; Shimaoka, Y; Tada, H; Watanabe, Y; Yagoro, A, 1998) |
| "We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years." | 1.29 | Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease. ( Amino, N; Asahi, K; Hidaka, Y; Iwatani, Y; Kashiwai, T; Tada, H; Tamaki, H, 1995) |
| "Visualization of thyroidal and orbital Graves' disease is feasible, but further investigation is necessary to establish the role of [111In-DTPA-D-Phe1]octreotide scintigraphy in representing disease activity and expression and in predicting therapeutical outcome." | 1.29 | [111In-DTPA-D-Phe1] octreotide scintigraphy in thyroidal and orbital Graves' disease: a parameter for disease activity? ( Hooijkaas, H; Kooy, PP; Krenning, EP; Oei, HY; Postema, PT; Reubi, JC; van den Bosch, WA; van der Loos, T; Wiersinga, WM; Wijngaarde, R, 1994) |
| "Wegener's granulomatosis is a well-defined systemic vasculitic syndrome that primarily affects the upper and lower respiratory tracts and the kidney." | 1.29 | Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis. ( Gal, AA; LiVolsi, VA; Masor, JJ, 1994) |
| "The patients had Graves' disease, but no other immune-mediated diseases, had not yet received specific treatment for their ophthalmopathy and were euthyroid during the entire study period." | 1.28 | Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy. ( Koornneef, L; Mourits, MP; Prummel, MF; Van der Gaag, R; Wiersinga, WM, 1992) |
| "Pure gonadal dysgenesis with 46,XX genotype is a rare abnormality with unknown etiology." | 1.28 | 46,XX gonadal dysgenesis with epibulbar dermoid. ( Copeland, KC; Quayle, SA, 1991) |
| " One hundred and eighty-six were given a dose adjusted for thyroid size and radioactive iodine uptake (Protocol 1), and a second group received the same dosage followed by antithyroid drug therapy plus potassium iodide for 15 days (Protocol 2)." | 1.28 | Comparison of RA 131I treatment protocols for Graves' disease. ( DeGroot, LJ; Mangklabruks, A; McCormick, M, 1990) |
| "Ocular myasthenia gravis was managed with an anticholinesterase agent in combination with oral corticosteroids that provided additional control." | 1.25 | Ocular myasthenia gravis and Hashimoto's thyroiditis. ( Osher, RH; Smith, JL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (53.85) | 18.7374 |
| 1990's | 16 (41.03) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 1 (2.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Preiss, D | 1 |
| Cleland, S | 1 |
| Sattar, N | 1 |
| Horster, FA | 3 |
| Wildmeister, W | 2 |
| Kashiwai, T | 2 |
| Tada, H | 2 |
| Asahi, K | 1 |
| Hidaka, Y | 2 |
| Tamaki, H | 2 |
| Iwatani, Y | 2 |
| Amino, N | 3 |
| Kung, AW | 1 |
| Yau, CC | 1 |
| Cheng, A | 1 |
| Postema, PT | 1 |
| Krenning, EP | 1 |
| Wijngaarde, R | 1 |
| Kooy, PP | 1 |
| Oei, HY | 1 |
| van den Bosch, WA | 1 |
| Reubi, JC | 1 |
| Wiersinga, WM | 2 |
| Hooijkaas, H | 1 |
| van der Loos, T | 1 |
| Masor, JJ | 1 |
| Gal, AA | 1 |
| LiVolsi, VA | 1 |
| Edmonds, CJ | 1 |
| Tellez, M | 1 |
| Minniti, G | 1 |
| Jaffrain-Rea, ML | 1 |
| Lunardi, P | 1 |
| Gulino, A | 1 |
| Tamburrano, G | 1 |
| Watanabe, Y | 1 |
| Shimaoka, Y | 1 |
| Yagoro, A | 1 |
| Fujikado, T | 1 |
| Siglin, JC | 1 |
| Mattie, DR | 1 |
| Dodd, DE | 1 |
| Hildebrandt, PK | 1 |
| Baker, WH | 1 |
| Fells, P | 1 |
| Osher, RH | 1 |
| Smith, JL | 1 |
| Hiromatsu, Y | 1 |
| Sato, M | 1 |
| Tanaka, K | 1 |
| Nonaka, K | 1 |
| Kojima, K | 1 |
| Sato, K | 1 |
| Kurose, S | 1 |
| Hoshino, T | 1 |
| Nakashima, A | 1 |
| Prummel, MF | 1 |
| Van der Gaag, R | 1 |
| Mourits, MP | 1 |
| Koornneef, L | 1 |
| Gomez, JM | 1 |
| Soler, J | 1 |
| Navarro, MA | 1 |
| Marcocci, C | 1 |
| Bartalena, L | 1 |
| Bogazzi, F | 1 |
| Bruno-Bossio, G | 1 |
| Lepri, A | 1 |
| Pinchera, A | 1 |
| Quayle, SA | 1 |
| Copeland, KC | 1 |
| Nagy, EV | 1 |
| Kalman, K | 1 |
| Szabo, J | 1 |
| Bako, G | 1 |
| Gergely, L | 1 |
| Leövey, A | 1 |
| Imai, Y | 1 |
| Odajima, R | 1 |
| Shimizu, T | 1 |
| Shishiba, Y | 1 |
| Barth, A | 1 |
| Probst, P | 1 |
| Bürgi, H | 1 |
| DeGroot, LJ | 2 |
| Mangklabruks, A | 1 |
| McCormick, M | 1 |
| Miyai, K | 1 |
| Klein, E | 2 |
| Mahaux, JE | 1 |
| Nagel, M | 1 |
| Schneider, C | 1 |
| Nolan, J | 1 |
| Johnston, MV | 1 |
| Larsen, PR | 1 |
| Algvere, P | 1 |
| Almqvist, S | 1 |
| Backlund, EO | 1 |
| Hamburger, JI | 1 |
| Sugar, HS | 1 |
| Mahto, RS | 1 |
| Singh, SP | 1 |
| McKenzie, JM | 1 |
| Fellinger, K | 1 |
| Bergmann, H | 1 |
| Erd, W | 1 |
| Höfer, R | 1 |
| Kolarz, G | 1 |
| Maddison, J | 1 |
| Maddison, RN | 1 |
| Studer, H | 1 |
| Jackson, IM | 1 |
| Hall, R | 1 |
| Reinwein, D | 1 |
| Richardson, J | 1 |
| Walsh, M | 1 |
2 reviews available for thyroxine and Eye Disorders
| Article | Year |
|---|---|
[Results of the thyroid gland function diagnosis with radioiodine in hyperthyroidism and endocrine ophthalmopathies].
Topics: Exophthalmos; Eye Diseases; Humans; Hyperthyroidism; Iodine Radioisotopes; Protein Binding; Radionuc | 1965 |
Current concepts in management of thyroid disease.
Topics: Eye Diseases; Graves Disease; Humans; Iodine Isotopes; Long-Acting Thyroid Stimulator; Methimazole; | 1970 |
4 trials available for thyroxine and Eye Disorders
| Article | Year |
|---|---|
[Endocrine orbitopathy. Results of therapy in patients with reference to new pathogenetic aspects].
Topics: Adult; Aged; Coumarins; Drug Combinations; Eye Diseases; Female; Goiter; Humans; Hydroxyethylrutosid | 1983 |
The incidence of ophthalmopathy after radioiodine therapy for Graves' disease: prognostic factors and the role of methimazole.
Topics: Adult; Aged; Autoantibodies; Eye Diseases; Female; Graves Disease; Humans; Hypothyroidism; Immunoglo | 1994 |
Treatment of Graves' disease by carbimazole: high dose with thyroxine compared to titration dose.
Topics: Adult; Antibodies; Carbimazole; Dose-Response Relationship, Drug; Eye Diseases; Female; Graves Disea | 1994 |
Orbital radiotherapy combined with high dose systemic glucocorticoids for Graves' ophthalmopathy is more effective than radiotherapy alone: results of a prospective randomized study.
Topics: Adult; Combined Modality Therapy; Eye; Eye Diseases; Female; Glucocorticoids; Graves Disease; Humans | 1991 |
33 other studies available for thyroxine and Eye Disorders
| Article | Year |
|---|---|
Research digest: topical trials in thyroid disease.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Clinical Trials as Topic; Eye Diseases; H | 2017 |
Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease.
Topics: Adult; Aged; Exophthalmos; Eye Diseases; Female; Graves Disease; Humans; Immunoglobulins, Thyroid-St | 1995 |
[111In-DTPA-D-Phe1] octreotide scintigraphy in thyroidal and orbital Graves' disease: a parameter for disease activity?
Topics: Eye; Eye Diseases; Graves Disease; Humans; Indium Radioisotopes; Methimazole; Octreotide; Pentetic A | 1994 |
Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis.
Topics: Azathioprine; Eye Diseases; Female; Granulomatosis with Polyangiitis; Humans; Kidney; Middle Aged; P | 1994 |
15-year-old boy with ocular palsy and headache. Invasive macroprolactinoma.
Topics: Adolescent; Bromocriptine; Cortisone; Dopamine Agonists; Eye Diseases; Headache; Humans; Male; Pitui | 1996 |
Low response of the thyroid gland to endogenous thyrotropin increased by thyrotropin-releasing hormone in patients with euthyroid Graves' disease.
Topics: Adolescent; Adult; Eye Diseases; Female; Graves Disease; Humans; Hyperthyroidism; Immunoglobulins, T | 1998 |
A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate.
Topics: Animals; Body Weight; Drinking; Eating; Estrus; Eye Diseases; Female; Male; Micronucleus Tests; Orga | 2000 |
Surgical management of dysthyroid eye disease: a review.
Topics: Eye Diseases; Humans; Thyroid Diseases; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1977 |
Ocular myasthenia gravis and Hashimoto's thyroiditis.
Topics: Adult; Diplopia; Eye Diseases; Female; Goiter; Humans; Myasthenia Gravis; Prednisone; Pyridostigmine | 1975 |
Anti-eye muscle antibodies and hypothyroid Graves' disease: a case report.
Topics: Aged; Autoantibodies; Blotting, Western; Eye Diseases; Graves Disease; Humans; Hypothyroidism; Immun | 1992 |
Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy.
Topics: Adult; Eye Diseases; Female; Graves Disease; Humans; Male; Middle Aged; Predictive Value of Tests; P | 1992 |
Thyroid stimulating antibodies in patients with Graves' ophthalmopathy.
Topics: Adolescent; Adult; Antibodies; Cyclic AMP; Eye Diseases; Female; Graves Disease; Humans; In Vitro Te | 1991 |
46,XX gonadal dysgenesis with epibulbar dermoid.
Topics: Adolescent; Dermoid Cyst; Eye Diseases; Female; Follicle Stimulating Hormone; Gonadal Dysgenesis; Hu | 1991 |
Sera but not immunoglobulins of ophthalmic Graves' patients stimulate human embryonal fibroblasts' biosynthetic activity in culture.
Topics: Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Eye Diseases; Fibroblasts; Glycosaminoglycans; G | 1991 |
Serum hyaluronan concentration determined by radiometric assay in patients with pretibial myxedema and Graves' ophthalmopathy.
Topics: Adult; Autoantibodies; Eye Diseases; Female; Graves Disease; Humans; Hyaluronic Acid; Immunoglobulin | 1990 |
Identification of a subgroup of Graves' disease patients at higher risk for severe ophthalmopathy after radioiodine.
Topics: Eye Diseases; Graves Disease; Humans; Iodine Radioisotopes; Retrospective Studies; Thyroxine | 1991 |
Comparison of RA 131I treatment protocols for Graves' disease.
Topics: Combined Modality Therapy; Eye Diseases; Female; Graves Disease; Humans; Hypothyroidism; Iodine Radi | 1990 |
Improvement of infiltrative ophthalmopathy in parallel with decrease of thyroid-stimulating antibody (TSAb) activity in two patients with hypothyroid Graves' disease.
Topics: Antibodies; Eye Diseases; Female; Graves Disease; Humans; Immunoglobulin G; Immunoglobulins, Thyroid | 1989 |
[Basdowian ophthalmic diseases. Pathogenic role of L-triiodothyronine and of LATS. Therapeutic role of L-thyroxine, of d-thyroxine and of corticoids].
Topics: Antithyroid Agents; Betamethasone; Dextrothyroxine; Eye Diseases; Graves Disease; Humans; Hyperthyro | 1967 |
[Treatment of endocrine ophthalmopathy].
Topics: Endocrine System Diseases; Eye Diseases; Glucocorticoids; Humans; Hyperthyroidism; Hypnotics and Sed | 1974 |
Atromid-S in eye disease.
Topics: Blood Coagulation; Cholesterol; Clofibrate; Coronary Disease; Diabetic Retinopathy; Eye Diseases; Fa | 1974 |
[Therapy of endocrine ophthalmopathy].
Topics: Exophthalmos; Eye Diseases; Humans; Hyperthyroidism; Long-Term Care; Prednisone; Thyroxine | 1972 |
Unilateral proptosis due to orbital pseudotumor in a patient with Hashimoto's thyroiditis.
Topics: Adult; Blepharoptosis; Dexamethasone; Diagnosis, Differential; Eye Diseases; Female; Functional Late | 1972 |
Pterional orbital decompression in progressive ophthalmopathy of Graves' disease II. A follow-up study.
Topics: Adult; Aged; Diplopia; Exophthalmos; Eye Diseases; Female; Follow-Up Studies; Graves Disease; Humans | 1973 |
What the internist should know about the ophthalmopathy of Graves' disease.
Topics: Adult; Diplopia; Eye; Eye Diseases; Eye Injuries; Eye Manifestations; Eyelid Diseases; Female; Glauc | 1972 |
Ocular features of hypothyroidism.
Topics: Age Factors; Aged; Cataract; Eye Diseases; Eyelashes; Eyelid Diseases; Female; Humans; Hypertension; | 1972 |
35-S-sulfate uptake by mouse harderian gland: effect of serum from patients with Graves' disease.
Topics: Animals; Chromatography; Eye Diseases; Graves Disease; Hyperthyroidism; Hypothyroidism; Immunoglobul | 1971 |
[Thyroid gland inhibition test in patients with endocrine ophthalmic diseases].
Topics: Adult; Aged; Diagnosis, Differential; Eye Diseases; Eye Manifestations; Graves Disease; Humans; Hype | 1971 |
The associations between various disabilities found in older people.
Topics: Adult; Aged; Aging; Androgens; Arcus Senilis; Body Temperature; Coronary Disease; Electrocardiograph | 1969 |
[Endocrine ophthalmopathy].
Topics: Exophthalmos; Eye Diseases; Graves Disease; Humans; Hyperthyroidism; Myxedema; Thyroid Gland; Thyrox | 1969 |
Pituitary enlargement resulting from primary thyroid disease.
Topics: Exudates and Transudates; Eye Diseases; Female; Humans; Hyperplasia; Hypothyroidism; Middle Aged; Pi | 1970 |
[On drug therapy of endocrine ophthalmopathy].
Topics: Edema; Exophthalmos; Eye Diseases; Eyelids; Humans; Long-Acting Thyroid Stimulator; Prednisone; Thyr | 1967 |
Uveal effusion as a sign of myxoedema.
Topics: Eye Diseases; Eye Manifestations; Female; Humans; Middle Aged; Myxedema; Retinal Detachment; Thyroxi | 1969 |