thyroxine has been researched along with Encephalopathy, Traumatic in 6 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, C | 1 |
| Luo, Y | 1 |
| Peng, L | 1 |
| Huang, Z | 1 |
| Pan, Y | 1 |
| Chen, Y | 1 |
| Chang, J | 1 |
| Yin, R | 1 |
| Wen, J | 1 |
| Ma, B | 1 |
| Zuo, W | 1 |
| Zhang, X | 1 |
| Wei, J | 1 |
| Zhang, Z | 1 |
| Yu, J | 1 |
| Wang, P | 1 |
| Lin, L | 1 |
| Liu, R | 1 |
| Zeng, R | 1 |
| Ma, H | 1 |
| Zhao, Y | 1 |
| Malomo, TA | 1 |
| Rabiu, TB | 1 |
| Udoh, DO | 1 |
| Komolafe, EO | 1 |
| Shokunbi, MT | 1 |
| Frenette, AJ | 1 |
| Williamson, D | 1 |
| Williams, V | 1 |
| Lagacé, AM | 1 |
| Charbonney, E | 1 |
| Serri, K | 1 |
| Heather, NL | 1 |
| Derraik, JG | 1 |
| Chiavaroli, V | 1 |
| Hofman, PL | 1 |
| Cutfield, WS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Efficacy and Safety of Levothyroxine in Brain Death Organ Donors: a Randomized Controlled Trial[NCT02211053] | Phase 4 | 15 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Recruitment was too slow and we cannot anticipate to recruit the target sample size) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thyroxine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
A Pilot Randomized Controlled Trial Comparing Levothyroxine to Placebo in Neurologically Deceased Donors.
Topics: Adult; Brain Death; Brain Injuries, Traumatic; Double-Blind Method; Echocardiography; Feasibility St | 2019 |
5 other studies available for thyroxine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Expression of Notch and Wnt/β-catenin signaling pathway in acute phase severe brain injury rats and the effect of exogenous thyroxine on those pathways.
Topics: Animals; Brain Injuries, Traumatic; Humans; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thyr | 2021 |
Diagnosis and treatment of low T3 syndrome in neurocritical patients.
Topics: Adult; Aged; Brain Injuries, Traumatic; Cerebral Hemorrhage; Critical Care; Euthyroid Sick Syndromes | 2020 |
iTRAQ-based proteomic profiling reveals protein alterations after traumatic brain injury and supports thyroxine as a potential treatment.
Topics: Animals; Behavior, Animal; Brain Injuries, Traumatic; Gene Ontology; Isotope Labeling; Male; Protein | 2021 |
Thyroid Hormone Profile in a Population of Nigerian Patients with Traumatic Brain Injury.
Topics: Adolescent; Brain Injuries, Traumatic; Female; Humans; Hypothyroidism; Male; Middle Aged; Nigeria; T | 2018 |
Increasing severity of traumatic brain injury in early childhood is associated with a progressive reduction in long-term serum thyroid-stimulating hormone concentrations.
Topics: Abbreviated Injury Scale; Brain Injuries, Traumatic; Child, Preschool; Humans; Infant; Thyrotropin; | 2016 |