Page last updated: 2024-11-06

thyroxine and Embryopathies

thyroxine has been researched along with Embryopathies in 122 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
" Intra-amniotic levothyroxine (L-T4) administration was performed, and the fetal goiter decreased in size."7.85Fetal goitrous hypothyroidism treated by intra-amniotic levothyroxine administration: case report and review of the literature. ( Kobayashi, M; Naito, A; Nemoto, A; Saito, T; Sugita, K; Yagasaki, H, 2017)
"The objective of the study was to evaluate the feasibility, safety, and effectiveness of intrauterine l-thyroxine treatment in a large cohort with nonimmune fetal goitrous hypothyroidism."7.75Experience with intraamniotic thyroxine treatment in nonimmune fetal goitrous hypothyroidism in 12 cases. ( Bertrand, AM; Castanet, M; Guibourdenche, J; Luton, D; Polak, M; Ribault, V; Vuillard, E, 2009)
"To test the hypothesis that thyroglobulin (Tg) and free T4 (FT4) concentrations more than 2SD from the control mean are not increased in pregnancy in an iodine replete area in the absence of elevated TSH concentrations."7.72Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism. ( Faix, JD; Haddow, JE; Klein, RZ; Meter, RA; Mitchell, ML; Sargent, JD; Waisbren, SE, 2003)
" In this report we describe a patient with Graves' disease diagnosed in early pregnancy and treated with propylthiouracil, which resulted in a large fetal goitre and fetal hypothyroidism."7.69In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil. ( Bos, AF; Derksen, JT; Rouwé, CW; Van Loon, AJ, 1995)
"We present a case of persistent fetal supraventricular tachycardia where transplacental and direct fetal treatment with amiodarone caused an iatrogenic hypothyroidism."7.69Fetal hypothyroidism as a complication of amiodarone treatment for persistent fetal supraventricular tachycardia. ( Bougatef, A; De Catte, L; De Schepper, J; De Wolf, D; Foulon, W; Smitz, J, 1994)
"We assessed the post-natal thyroid function in eight infants of mothers with Graves' disease whose thyroid function at birth was suppressed by maternal ingestion of propylthiouracil during pregnancy."7.67Recovery from foetal hypothyroidism: evidence for the safety of breast-feeding while taking propylthiouracil. ( Ishikawa, N; Ito, K; Momotani, N; Noh, J; Yamashita, R; Yoshimoto, M, 1989)
" The nonhalogenated thyroid hormone analog 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) was administered to pregnant ewes to determine if this compound could prevent cretinism in the thyroidectomized fetal lamb."7.66Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine. ( Bachrach, LK; Burrow, GN; Kent, G; Kudlow, JE; Silverberg, JD, 1982)
"Hypothyroidism is one of the most common endocrine disorders in young women and affects 3% to 4% of all pregnancies."6.52Combination Levothyroxine + Liothyronine Treatment in Pregnancy. ( Foeller, ME; Silver, RM, 2015)
"The goiters shrunk and the polyhydramnios improved in response to the in utero treatment."5.72Successful intra-amniotic levothyroxine treatment for fetal goitrous hypothyroidism in a triplet pregnancy. ( Hidaka, N; Kitadai, Y; Nakanami, N; Sato, M; Soejima, C; Sumie, M, 2022)
"Fetal goitrous hypothyroidism is a rare entity and is caused mainly by maternal treatment of Graves' disease (GD)."5.51Graves' disease complicated by fetal goitrous hypothyroidism treated with intra-amniotic administration of levothyroxine. ( Campos, RA; Castro, JM; Machado, CM; Oliveira, MJ, 2019)
"Treatment with carbimazole along with thyroxine was followed by a live birth at 35 wk; but the baby developed severe fatal neonatal thyrotoxicosis with crisis on day 9 and died on day 12."5.42Fetal Hyperthyroidism: Intrauterine Treatment with Carbimazole in Two Siblings. ( Batra, CM; Gupta, N; Gupta, V; Menon, PS, 2015)
"After treatment of fetal hyperthyroidism through oral maternal administration of methimazole (MMI) starting at 33 weeks gestation, fetal heart rate and amniotic fluid volume returned to normal ranges."5.40A case of fetal hyperthyroidism treated with maternal administration of methimazole. ( Hayashi, S; Ishii, K; Mitsuda, N; Murata, M; Sasahara, J; Sato, Y, 2014)
"Two pregnant women with Graves' disease were overtreated with ATDs inducing iatrogenic goiter in the fetuses."5.37Graves' disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxine. ( Bliddal, S; Brocks, V; Feldt-Rasmussen, U; Rasmussen, ÅK; Skovbo, P; Sundberg, K, 2011)
" For goitrous fetal hypothyroidism leading to hydramnios, repeated intra-amniotic injections of thyroxine have been reported to decrease the size of the fetal thyroid."4.90Fetal thyroïdology. ( Luton, D; Polak, M, 2014)
" For goitrous fetal hypothyroidism leading to hydramnios, repeated intra-amniotic injections of thyroxine have been reported to decrease the size of the fetal thyroid."4.87Thyroid disorders during pregnancy: impact on the fetus. ( Polak, M, 2011)
" For goitrous nonimmune fetal hypothyroidism leading to hydramnios, intra-amniotic injections of thyroxine have been reported to decrease the size of the fetal thyroid."4.86Therapeutic approach of fetal thyroid disorders. ( Polak, M; Van Vliet, G, 2010)
" In contrast, subclinical hypothyroidism seems to improve with thyroxine treatment."4.85[Clinical guideline for the diagnosis and treatment of subclinical thyroid dysfunction in pregnancy. Working Group on Subclinical Thyroid Dysfunction of the Spanish Endocrinology Society]. ( Alonso Pedrol, N; Cantón Blanco, A; Corrales Hernández, JJ; Galofré Ferrater, JC; Lajo Morales, T; Pérez Corral, B; Pérez Pérez, A; Tortosa Henzi, F, 2009)
"Recently, the recommended dose for iodine intake during pregnancy had been increased from 200 to 250 microg/day, because recent studies revealed that even mild-to-moderate iodine intake might affect the neuropsychological development of the child."4.85Thyroid diseases in pregnancy. ( Gärtner, R, 2009)
"Around 1-2% of pregnant women receive levothyroxine treatment for overt hypothyroidism."4.83Hypothyroidism in the pregnant woman. ( , 2006)
" Firstly, in infants with a defect of glandular ontogenesis (congenital hypothyroidism), the participation of maternal thyroid hormones to the fetal circulating thyroxine environment is normal and, therefore, risk of brain damage results exclusively from the insufficient hormone production by the abnormal fetal thyroid gland."4.80The potential repercussions of maternal, fetal, and neonatal hypothyroxinemia on the progeny. ( Delange, F; Glinoer, D, 2000)
"5%) required further levothyroxine (L-T4) supplementation due to CeH or, in one case, due to primary hypothyroidism."4.12Follow-Up of Thyroid Function in Children With Neonatal Hyperthyroidism. ( Kucharska, A; Pyrżak, B; Rumińska, M; Witkowska-Sędek, E, 2022)
"The hyperthyroid mother underwent subtotal thyroidectomy before pregnancy and regularly took levothyroxine to avoid hypothyroidism, but still had a high-level thyroid-stimulating hormone receptor antibody (TRAb)."4.12A hypothyroid mother after subtotal thyroidectomy delivered a newborn with hyperthyroidism from fetal stage: a case report. ( Fan, L; Gao, Y; Hou, X; Li, L; Peng, C; Sun, W; Zhang, X, 2022)
"We report a case of fetal hypothyroid goiter secondary to inadvertent excess maternal iodine ingestion from infertility supplements."3.88Iodine-Induced Fetal Hypothyroidism: Diagnosis and Treatment with Intra-Amniotic Levothyroxine. ( Chmait, RH; Chon, AH; Geffner, ME; Hardley, MT; Mestman, J; Nguyen, CT, 2018)
" Intra-amniotic levothyroxine (L-T4) administration was performed, and the fetal goiter decreased in size."3.85Fetal goitrous hypothyroidism treated by intra-amniotic levothyroxine administration: case report and review of the literature. ( Kobayashi, M; Naito, A; Nemoto, A; Saito, T; Sugita, K; Yagasaki, H, 2017)
"The objective of the study was to evaluate the feasibility, safety, and effectiveness of intrauterine l-thyroxine treatment in a large cohort with nonimmune fetal goitrous hypothyroidism."3.75Experience with intraamniotic thyroxine treatment in nonimmune fetal goitrous hypothyroidism in 12 cases. ( Bertrand, AM; Castanet, M; Guibourdenche, J; Luton, D; Polak, M; Ribault, V; Vuillard, E, 2009)
"We experienced a case of fetal goitrous hypothyroidism in an infant delivered by a 33-year-old woman receiving 300 mg/day of propylthiouracil (PTU) for hyperthyroidism due to Graves' disease."3.74Successful intrauterine therapy for fetal goitrous hypothyroidism during late gestation. ( Abe-Gotyo, N; Eto, Y; Kanno, K; Miyata, I; Seo, M; Sugiura, K; Tajima, A; Tanaka, T; Teramoto, S; Yoshikawa, H, 2007)
"We report the results of intrauterine L-thyroxine therapy, and the long-term follow-up in a fetus who presented at 32 weeks' gestation with goitrous hypothyroidism, hyperextension of the neck, and polyhydramnios."3.73Intrauterine therapy of goitrous hypothyroidism in a boy with a new compound heterozygous mutation (Y453D and C800R) in the thyroid peroxidase gene. A long-term follow-up. ( Börgel, K; Bramswig, JH; Holzgreve, W; Pohlenz, J, 2005)
" For fetal hyperthyroidism, the mother received antithyroid drugs; for fetal hypothyroidism, maternal antithyroid treatment was reduced, and thyroxine was injected into the amniotic sac."3.72Graves' disease in pregnancy: prospective evaluation of a selective invasive treatment protocol. ( Nachum, Z; Rakover, Y; Shalev, E; Weiner, E, 2003)
"To test the hypothesis that thyroglobulin (Tg) and free T4 (FT4) concentrations more than 2SD from the control mean are not increased in pregnancy in an iodine replete area in the absence of elevated TSH concentrations."3.72Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism. ( Faix, JD; Haddow, JE; Klein, RZ; Meter, RA; Mitchell, ML; Sargent, JD; Waisbren, SE, 2003)
"Three women aged 36, 34 and 33 years, with primary hypothyroidism were euthyroid whilst on levothyroxine treatment."3.71[Timely recognition and treatment of hypothyroidism in pregnant women: benefit for the child]. ( Boer, K; Corssmit, EP; Prummel, MF; Wiersinga, WM, 2001)
" After this medication was discontinued at 29 weeks, a fetal hypothyroidism was confirmed by cordocentesis, and two doses of levothyroxine were administered by amniocentesis."3.70Diagnosis and treatment in utero of goiter with hypothyroidism caused by iodide overload. ( Albisu, MA; Bellart, J; Carrascosa, A; Carreras, E; Potau, N; Vicens-Calvet, E, 1998)
"The diagnosis of fetal hypothyroidism is based at present on measurements of TSH and free thyroxine (FT4) in fetal blood samples obtained by cordocentesis."3.70Maternal compound W serial measurements for the management of fetal hypothyroidsm. ( Beck-Peccoz, P; Cortelazzi, D; Fisher, DA; Morpurgo, PS; Wu, SY; Zamperini, P, 1999)
"Although the placenta is only a limited barrier for the transfer of thyroxine (T4) to the fetus, we have recently demonstrated that maternal T4 does not suffice to prevent the effects of in utero hypothyroidism."3.69A simple model for studying the correction of in utero hypothyroidism in the rat. ( Rigler, O; Rozin, A; Sack, J; Weller, A, 1995)
"We present a case of persistent fetal supraventricular tachycardia where transplacental and direct fetal treatment with amiodarone caused an iatrogenic hypothyroidism."3.69Fetal hypothyroidism as a complication of amiodarone treatment for persistent fetal supraventricular tachycardia. ( Bougatef, A; De Catte, L; De Schepper, J; De Wolf, D; Foulon, W; Smitz, J, 1994)
" In this report we describe a patient with Graves' disease diagnosed in early pregnancy and treated with propylthiouracil, which resulted in a large fetal goitre and fetal hypothyroidism."3.69In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil. ( Bos, AF; Derksen, JT; Rouwé, CW; Van Loon, AJ, 1995)
"We investigated the effect of hyperthyroidism and hypothyroidism on the myocardial glycogen metabolism by quantitating 125I-insulin binding, glycogen content, glycogen synthase and phosphorylase enzyme activities in the newborn rabbit."3.67Regulation of neonatal heart glycogen metabolism by thyroxine. ( Devaskar, SU, 1986)
"We compared fetal and maternal serum indexes of thyroid status at delivery in 70 patients with Graves' disease who required therapy with thionamides (such as propylthiouracil) during pregnancy."3.67Antithyroid drug therapy for Graves' disease during pregnancy. Optimal regimen for fetal thyroid status. ( Ishikawa, N; Ito, K; Momotani, N; Noh, J; Oyanagi, H, 1986)
"We assessed the post-natal thyroid function in eight infants of mothers with Graves' disease whose thyroid function at birth was suppressed by maternal ingestion of propylthiouracil during pregnancy."3.67Recovery from foetal hypothyroidism: evidence for the safety of breast-feeding while taking propylthiouracil. ( Ishikawa, N; Ito, K; Momotani, N; Noh, J; Yamashita, R; Yoshimoto, M, 1989)
"The sonographic diagnosis of a fetal goiter, confirmed at delivery, is described in a fetus exposed to large doses of propylthiouracil, which was administered to the mother."3.66Antenatal diagnosis and treatment of a fetal goiter. ( Bolognese, RJ; Librizzi, RJ; Scharf, JI; Weiner, S, 1980)
" The nonhalogenated thyroid hormone analog 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) was administered to pregnant ewes to determine if this compound could prevent cretinism in the thyroidectomized fetal lamb."3.66Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine. ( Bachrach, LK; Burrow, GN; Kent, G; Kudlow, JE; Silverberg, JD, 1982)
" Because of the potential risk of fetal hypothyroidism, an amniocentesis, with an injection of 500 mug of thyroxine, was performed weekly from week 33 until delivery."3.65Intra-amniotic injection of thyroxine (T4Y to a human fetus. Evidence for conversion of T4 to reverse T3. ( Fismer, FA; Giles, H; Lightner, ES; Woolfenden, J, 1977)
"Hypothyroidism is one of the most common endocrine disorders in young women and affects 3% to 4% of all pregnancies."2.52Combination Levothyroxine + Liothyronine Treatment in Pregnancy. ( Foeller, ME; Silver, RM, 2015)
"Pregnancy is accompanied by changes in thyroid function."2.41[Pregnancy (conception) in hyper- or hypothyroidism]. ( Boer, K; Corssmit, EP; Prummel, MF; Wiersinga, WM, 2001)
"The recognition and treatment of fetal hypothyroidism are believed to be important to optimize growth and intellectual development in affected fetuses."2.39Antenatal diagnosis and treatment of fetal goitrous hypothyroidism: case report and review of the literature. ( Abuhamad, AZ; Evans, AT; Fisher, DA; Pyle, PG; Slotnick, RN; Warsof, SL; Wu, SY, 1995)
"The goiters shrunk and the polyhydramnios improved in response to the in utero treatment."1.72Successful intra-amniotic levothyroxine treatment for fetal goitrous hypothyroidism in a triplet pregnancy. ( Hidaka, N; Kitadai, Y; Nakanami, N; Sato, M; Soejima, C; Sumie, M, 2022)
"Fetal goitrous hypothyroidism is a rare entity and is caused mainly by maternal treatment of Graves' disease (GD)."1.51Graves' disease complicated by fetal goitrous hypothyroidism treated with intra-amniotic administration of levothyroxine. ( Campos, RA; Castro, JM; Machado, CM; Oliveira, MJ, 2019)
"Fetal tachyarrhythmias complicate 0."1.42Fetuses of Mothers with Thyroid Disease May Be at Higher Risk of Developing Supraventricular Tachycardia. ( Fish, FA; Johnson, JA; Kavanaugh-McHugh, A; Killen, SA; Lu, Z; Williams, P, 2015)
"Treatment with carbimazole along with thyroxine was followed by a live birth at 35 wk; but the baby developed severe fatal neonatal thyrotoxicosis with crisis on day 9 and died on day 12."1.42Fetal Hyperthyroidism: Intrauterine Treatment with Carbimazole in Two Siblings. ( Batra, CM; Gupta, N; Gupta, V; Menon, PS, 2015)
"After treatment of fetal hyperthyroidism through oral maternal administration of methimazole (MMI) starting at 33 weeks gestation, fetal heart rate and amniotic fluid volume returned to normal ranges."1.40A case of fetal hyperthyroidism treated with maternal administration of methimazole. ( Hayashi, S; Ishii, K; Mitsuda, N; Murata, M; Sasahara, J; Sato, Y, 2014)
"Congenital hypothyroidism was confirmed by fetal blood sampling that was treated with weekly intra-amniotic injections of L-thyroxin."1.39Prenatal diagnosis and treatment perspective of fetal hypothyroidism with goiter. ( Gulraze, A; Kurdi, W; Niaz, FA; Tulbah, M, 2013)
"Two pregnant women with Graves' disease were overtreated with ATDs inducing iatrogenic goiter in the fetuses."1.37Graves' disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxine. ( Bliddal, S; Brocks, V; Feldt-Rasmussen, U; Rasmussen, ÅK; Skovbo, P; Sundberg, K, 2011)
"Umbilical blood revealed primary hypothyroidism with increased TSBAb, and the infant was given levothyroxine sodium."1.36Fetal goitrous hypothyroidism due to maternal thyroid stimulation-blocking antibody: a case report. ( Ashida, T; Hirabayashi, K; Kanai, M; Kikuchi, N; Kobara, H; Miyake, M; Nishio, S; Ohira, S; Osada, R; Shiozawa, T, 2010)
"The ultrasound screening revealed polyhydramnios (amniotic fluid index, 21 cm), a homogeneous solid mass of 3."1.35Intrauterine fetal goiter: diagnosis and management. ( Başer, I; Ergün, A; Fidan, U; Gezginç, K; Göktolga, U; Karaşahin, KE, 2008)
"Fetal goiter is a rare occurrence of which neonatal consequences are not always predictable."1.33[Correct procedure in the presence of a fetal goiter associated with hypothyroidism. Observations from three cases]. ( Duclos, B; Lenclen, R; Paupe, A; Ville, Y, 2006)
"In response to this in utero treatment, the goiter was reduced and polyhydramnios was improved."1.33Successful in utero treatment of fetal goitrous hypothyroidism: case report and review of the literature. ( Hashimoto, H; Hashimoto, K; Suehara, N, 2006)
"We present two cases of maternal Graves' disease complicated by fetal goitrous hypothyroidism."1.29In utero treatment of fetal goitrous hypothyroidism caused by maternal Graves' disease. ( Hadi, HA; Strickland, D, 1995)
"Mild hypothyroidism was diagnosed based on fetal serum obtained by percutaneous umbilical blood sampling at 29 weeks of gestation."1.28Early prenatal diagnosis and therapy of fetal hypothyroid goiter. ( Bianchi, A; Caruso, A; D'Errico, G; De Santis, M; Mancuso, S; Masini, L; Maussier, ML; Noia, G; Romagnoli, C; Tocci, A, 1992)
"Presence of polyhydramnios led to the ultrasound diagnosis of a fetal goiter."1.28Intrauterine diagnosis and treatment of fetal goitrous hypothyroidism. ( Clemons, RD; Clewell, WH; Finberg, HJ; Johnson, RL; Perelman, AH; Trujillo, L, 1990)
"At 26 weeks of gestation fetal hyperkinesia and fetal tachycardia developed."1.26Fetal thyrotoxicosis in utero. ( Petersen, S; Serup, J, 1979)

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-199032 (26.23)18.7374
1990's26 (21.31)18.2507
2000's29 (23.77)29.6817
2010's31 (25.41)24.3611
2020's4 (3.28)2.80

Authors

AuthorsStudies
Peng, C1
Sun, W1
Fan, L1
Li, L1
Zhang, X1
Gao, Y1
Hou, X1
Pyrżak, B1
Rumińska, M1
Witkowska-Sędek, E1
Kucharska, A1
Hidaka, N1
Soejima, C1
Sato, M1
Kitadai, Y1
Sumie, M1
Nakanami, N1
Machado, CM1
Castro, JM1
Campos, RA1
Oliveira, MJ1
Camm, EJ1
Inzani, I1
De Blasio, MJ1
Davies, KL1
Lloyd, IR1
Wooding, FBP1
Blache, D1
Fowden, AL1
Forhead, AJ1
García-García, E1
De Ceballos, RD1
Kobayashi, M1
Yagasaki, H1
Saito, T1
Nemoto, A1
Naito, A1
Sugita, K1
Hardley, MT1
Chon, AH1
Mestman, J1
Nguyen, CT1
Geffner, ME1
Chmait, RH1
Dębska, M2
Gietka-Czernel, M2
Kretowicz, P2
Filipecka-Tyczka, D1
Lewczuk, Ł1
Dangel, J1
Dębski, R1
Munoz, JL1
Gulraze, A1
Kurdi, W1
Tulbah, M1
Niaz, FA1
Namouz-Haddad, S1
Koren, G1
Lazarus, JH2
Polak, M5
Luton, D4
Fisher, DA7
Zgliczyński, W1
Ołtarzewski, M1
Sato, Y1
Murata, M1
Sasahara, J1
Hayashi, S1
Ishii, K1
Mitsuda, N1
Capone, CA1
Gebb, J1
Dar, P1
Shenoy, RU1
Khater, C1
Ceccaldi, PF1
Poujade, O1
Banigé, M1
Ottenwalter, A1
Batra, CM1
Gupta, V1
Gupta, N1
Menon, PS1
Johnson, JA1
Williams, P1
Lu, Z1
Kavanaugh-McHugh, A1
Fish, FA1
Killen, SA1
Foeller, ME1
Silver, RM1
Ahmed, RG1
Menut-Ruel, A1
Barthod, M1
Gauchez, AS1
Dupuis, C1
Charrie, A1
Dubois, C1
Leriche, A1
Polverelli, JF1
Althuser, M1
Jouk, PS1
Chabre, O1
Hanono, A1
Shah, B1
David, R1
Buterman, I1
Roshan, D1
Shah, S1
Lam, L1
Timor-Tritsch, I1
Mayor-Lynn, KA1
Rohrs, HJ1
Cruz, AC1
Silverstein, JH1
Richards, D1
Francois, A1
Hindryckx, A1
Vandecruys, H1
Van Schoubroeck, D1
Vanhole, C1
Allegaert, K1
Devlieger, R1
Peris Roig, B1
Calvo Rigual, F1
Tenias Burillo, JM1
Merchante Alfaro, A1
Presencia Rubio, G1
Miralles Dolz, F1
Galofré Ferrater, JC1
Corrales Hernández, JJ1
Pérez Corral, B1
Cantón Blanco, A1
Alonso Pedrol, N1
Pérez Pérez, A1
Lajo Morales, T1
Tortosa Henzi, F1
Ribault, V1
Castanet, M1
Bertrand, AM1
Guibourdenche, J2
Vuillard, E2
Gärtner, R1
Stoppa-Vaucher, S2
Francoeur, D1
Grignon, A1
Alos, N1
Pohlenz, J3
Hermanns, P1
Van Vliet, G3
Deladoëy, J2
Corral, E1
Reascos, M1
Preiss, Y1
Rompel, SM1
Sepulveda, W1
Yapakçi, E1
Kinik, ST1
Ohira, S1
Miyake, M1
Kobara, H1
Kikuchi, N1
Osada, R1
Ashida, T1
Hirabayashi, K1
Nishio, S1
Kanai, M1
Shiozawa, T1
Bliddal, S1
Rasmussen, ÅK1
Sundberg, K1
Brocks, V1
Skovbo, P1
Feldt-Rasmussen, U1
Kornacki, J1
Mroziński, B1
Skrzypczak, J1
Azria, E1
Carré, A1
Delezoide, AL1
Corbacioglu Esmer, A1
Gul, A1
Dagdeviren, H1
Turan Bakirci, I1
Sahin, O1
Lavado-Autric, R1
Ausó, E1
García-Velasco, JV1
Arufe, Mdel C1
Escobar del Rey, F1
Berbel, P1
Morreale de Escobar, G1
Mitchell, ML2
Klein, RZ2
Sargent, JD1
Meter, RA1
Haddow, JE2
Waisbren, SE2
Faix, JD2
Nachum, Z1
Rakover, Y2
Weiner, E2
Shalev, E2
Nathanielsz, PW1
Berghorn, KA1
Derks, JB1
Giussani, DA1
Docherty, C1
Unno, N1
Davenport, A1
Kutzlers, M1
Koenen, S1
Visser, GH1
Nijland, MJ1
FRENCH, FS1
VANWYK, JJ1
SCANLON, RT1
Chang, AY1
Chamberlain-Shea, H1
Carr, B1
Nath, CA1
Oyelese, Y1
Yeo, L1
Chavez, M1
Kontopoulos, EV1
Giannina, G1
Smulian, JC1
Vintzileos, AM1
Börgel, K1
Holzgreve, W1
Bramswig, JH1
Duclos, B1
Ville, Y1
Lenclen, R1
Paupe, A1
Hashimoto, H1
Hashimoto, K1
Suehara, N2
Simsek, M1
Mendilcioglu, I1
Mihci, E1
Karagüzel, G1
Taskin, O1
Glinoer, D2
Abalovich, M1
Miyata, I1
Abe-Gotyo, N1
Tajima, A1
Yoshikawa, H1
Teramoto, S1
Seo, M1
Kanno, K1
Sugiura, K1
Tanaka, T1
Eto, Y1
Kaklamanou, M1
Göktolga, U1
Karaşahin, KE1
Gezginç, K1
Fidan, U1
Ergün, A1
Başer, I1
Weiner, S1
Scharf, JI1
Bolognese, RJ1
Librizzi, RJ1
Bachrach, LK1
Kudlow, JE1
Silverberg, JD1
Kent, G1
Burrow, GN1
El-Zaheri, MM1
Vagenakis, AG1
Hinerfeld, L1
Emerson, CH1
Braverman, LE2
Connolly, KJ1
Pharoah, PO1
Sack, J1
Weller, A1
Rigler, O1
Rozin, A1
De Catte, L2
De Wolf, D1
Smitz, J2
Bougatef, A2
De Schepper, J2
Foulon, W2
Wu, SY3
Polk, DH1
Huang, WS1
Reviczky, A1
Wang, K1
Santini, F1
Cortelazzi, D2
Baggiani, AM1
Marconi, AM1
Beck-Peccoz, P3
Chopra, IJ2
Van Loon, AJ1
Derksen, JT1
Bos, AF1
Rouwé, CW1
Hadi, HA1
Strickland, D1
Abuhamad, AZ1
Warsof, SL1
Slotnick, RN1
Pyle, PG1
Evans, AT1
Roti, E2
Minelli, R1
Salvi, M1
Vanderpump, MP1
Ahlquist, JA1
Franklyn, JA1
Clayton, RN1
Richardson, B1
Korkola, S1
Asano, H1
Challis, J1
Polk, D1
Fraser, M1
Bajoria, R1
Fisk, NM1
Contractor, SF1
Momotani, N3
Noh, JY1
Ishikawa, N3
Ito, K3
Medeiros-Neto, G1
Bunduki, V1
Tomimori, E1
Gomes, S1
Knobel, M1
Martin, RT1
Zugaib, M1
Vicens-Calvet, E1
Potau, N1
Carreras, E1
Bellart, J1
Albisu, MA1
Carrascosa, A1
Asteria, C1
Rajanayagam, O1
Collingwood, TN1
Persani, L1
Romoli, R1
Mannavola, D1
Zamperini, P2
Buzi, F1
Ciralli, F1
Chatterjee, VK1
Palomaki, GE1
Allan, WC1
Williams, JR1
Knight, GJ1
Gagnon, J1
O'Heir, CE1
Hermos, RJ1
Mosh, N1
Morpurgo, PS1
Delange, F1
Perrotin, F1
Sembely-Taveau, C1
Haddad, G1
Lyonnais, C1
Lansac, J1
Body, G1
Wiersinga, WM2
Corssmit, EP2
Boer, K2
Prummel, MF2
Vanbesien, J1
Casteels, A1
De Bock, S1
Agrawal, P1
Ogilvy-Stuart, A1
Lees, C1
Morine, M1
Takeda, T1
Minekawa, R1
Sugiyama, T1
Wasada, K1
Mizutani, T1
Lutz, P1
Serup, J2
Petersen, S2
Walsh, MP1
Thomas, ID1
Lightner, ES1
Fismer, FA1
Giles, H1
Woolfenden, J1
Van Herle, AJ1
Young, RT1
Uller, RP1
Brinkman, CR1
Crandall, BF1
Hollingsworth, DR2
Belin, RP1
Parker, JC1
Moser, RJ1
McKean, H1
Horger, EO1
Kenimer, JG1
Azukizawa, M1
Hershman, JM1
Kansal, PC1
Leaming, AB1
Noia, G1
De Santis, M1
Tocci, A1
Maussier, ML1
D'Errico, G1
Bianchi, A1
Romagnoli, C1
Masini, L1
Caruso, A1
Mancuso, S1
Davidson, KM1
Richards, DS1
Schatz, DA1
Thorpe-Beeston, JG2
Nicolaides, KH2
Gosden, CM1
McGregor, AM1
Snijders, RJ1
Felton, CV1
Perelman, AH2
Johnson, RL2
Clemons, RD1
Finberg, HJ2
Clewell, WH2
Trujillo, L1
Hirsch, M1
Josefsberg, Z1
Schoenfeld, A1
Pertzelan, A1
Merlob, P1
Leiba, S1
Kohn, G1
Ovadia, J1
Lubin, E1
Laron, Z1
Noh, J2
Oyanagi, H1
Yamashita, R1
Yoshimoto, M1
Topliss, DJ1
Devaskar, SU1
Robuschi, G1
Emanuele, R1
d'Amato, L1
Gardini, E1
Foscolo, MS1
Gualerzi, C1
Benassi, L1
Gnudi, A1
Austin, E1
Reinfrank, RF1
Wiener, JD1
Pretell, EA1
Holt, AB1
Cheek, DB1
Kerr, GR1
Selenkow, HA1
Birnbaum, MD1
Hollander, CS1
Reynolds, JW1
Morrison, JC1
Boyd, M1
Friedman, BI1
Bucovaz, ET1
Whybrew, WD1
Koury, DN1
Wiser, WL1
Fish, SA1
Wahlberg, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Are IQs Low in Offspring of Euthyroid Women With Low T4?[NCT00147433]5,000 participants Observational2004-02-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

21 reviews available for thyroxine and Embryopathies

ArticleYear
Fetal thyroid disorders: Pathophysiology, diagnosis and therapeutic approaches.
    Journal of gynecology obstetrics and human reproduction, 2019, Volume: 48, Issue:4

    Topics: Antithyroid Agents; Female; Fetal Diseases; Gestational Age; Goiter; Humans; Hyperthyroidism; Hypoth

2019
Fetal pharmacotherapy 4: fetal thyroid disorders.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2014, Volume: 36, Issue:1

    Topics: Amniotic Fluid; Diagnosis, Differential; Female; Fetal Diseases; Goiter; Humans; Hyperthyroidism; Hy

2014
Fetal thyroïdology.
    Best practice & research. Clinical endocrinology & metabolism, 2014, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Amnion; Antithyroid Agents; Female; Fetal Diseases; Graves Disease; Humans; Hyper

2014
Combination Levothyroxine + Liothyronine Treatment in Pregnancy.
    Obstetrical & gynecological survey, 2015, Volume: 70, Issue:9

    Topics: Adult; Drug Therapy, Combination; Female; Fetal Diseases; Humans; Hypothyroidism; Maternal-Fetal Exc

2015
[Clinical guideline for the diagnosis and treatment of subclinical thyroid dysfunction in pregnancy. Working Group on Subclinical Thyroid Dysfunction of the Spanish Endocrinology Society].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:2

    Topics: Adult; Embryonic Development; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyroidism; Iodin

2009
Thyroid diseases in pregnancy.
    Current opinion in obstetrics & gynecology, 2009, Volume: 21, Issue:6

    Topics: Brain; Female; Fetal Death; Fetal Diseases; Hormone Replacement Therapy; Humans; Intelligence Tests;

2009
Therapeutic approach of fetal thyroid disorders.
    Hormone research in paediatrics, 2010, Volume: 74, Issue:1

    Topics: Female; Fetal Diseases; Fetus; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Pregnancy; Thyroxine

2010
Thyroid disorders during pregnancy: impact on the fetus.
    Hormone research in paediatrics, 2011, Volume: 76 Suppl 1

    Topics: Adult; Antithyroid Agents; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hyperthyroidism;

2011
Three-dimensional sonography in the evaluation and management of fetal goiter.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2005, Volume: 25, Issue:3

    Topics: Adult; Antithyroid Agents; Female; Fetal Diseases; Goiter; Humans; Hyperthyroidism; Imaging, Three-D

2005
Hypothyroidism in the pregnant woman.
    Drug and therapeutics bulletin, 2006, Volume: 44, Issue:7

    Topics: Female; Fetal Diseases; Humans; Hypothyroidism; Pregnancy; Pregnancy Complications; Pregnancy Outcom

2006
Unresolved questions in managing hypothyroidism during pregnancy.
    BMJ (Clinical research ed.), 2007, Aug-11, Volume: 335, Issue:7614

    Topics: Adult; Female; Fetal Diseases; Humans; Hypothyroidism; Postnatal Care; Pregnancy; Pregnancy Complica

2007
Significance of low thyroid-stimulating hormone in pregnancy.
    Current opinion in endocrinology, diabetes, and obesity, 2007, Volume: 14, Issue:5

    Topics: Autoantibodies; Child; Diagnosis, Differential; Female; Fetal Diseases; Graves Disease; Humans; Hype

2007
Antenatal diagnosis and treatment of fetal goitrous hypothyroidism: case report and review of the literature.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 1995, Volume: 6, Issue:5

    Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Fetal Diseases; Goiter; Humans; Hypothyroidism; Injectio

1995
Clinical review 80: Management of hyperthyroidism and hypothyroidism in the pregnant woman.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:5

    Topics: Antithyroid Agents; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn

1996
Consensus statement for good practice and audit measures in the management of hypothyroidism and hyperthyroidism. The Research Unit of the Royal College of Physicians of London, the Endocrinology and Diabetes Committee of the Royal College of Physicians o
    BMJ (Clinical research ed.), 1996, Aug-31, Volume: 313, Issue:7056

    Topics: Adrenergic beta-Antagonists; Carbimazole; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyro

1996
The potential repercussions of maternal, fetal, and neonatal hypothyroxinemia on the progeny.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:10

    Topics: Developmental Disabilities; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Hypothy

2000
[Pregnancy (conception) in hyper- or hypothyroidism].
    Nederlands tijdschrift voor geneeskunde, 2001, Apr-14, Volume: 145, Issue:15

    Topics: Adult; Antithyroid Agents; Disease Management; Dose-Response Relationship, Drug; Female; Fetal Disea

2001
Another reason for iodine prophylaxis.
    Lancet (London, England), 1990, Jun-16, Volume: 335, Issue:8703

    Topics: Adult; Child; Child, Preschool; Congenital Hypothyroidism; Developmental Disabilities; Female; Fetal

1990
Iodine-deficiency disorders.
    The Medical journal of Australia, 1989, Jun-19, Volume: 150, Issue:12

    Topics: Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Intelligence; Iod

1989
Thyroid function and dysfunction during pregnancy.
    Clinical obstetrics and gynecology, 1973, Volume: 16, Issue:3

    Topics: Abortion, Spontaneous; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyroidism; Maternal-Fet

1973
The use of drugs in influencing human fetal metabolism.
    Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Blood Transfusion, Intrauterine; Congenital Hypothyroidism; E

1974

Other Studies

101 other studies available for thyroxine and Embryopathies

ArticleYear
A hypothyroid mother after subtotal thyroidectomy delivered a newborn with hyperthyroidism from fetal stage: a case report.
    BMC pregnancy and childbirth, 2022, Apr-12, Volume: 22, Issue:1

    Topics: Antithyroid Agents; Female; Fetal Diseases; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism;

2022
Follow-Up of Thyroid Function in Children With Neonatal Hyperthyroidism.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Female; Fetal Diseases; Follow-Up Studies; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism;

2022
Successful intra-amniotic levothyroxine treatment for fetal goitrous hypothyroidism in a triplet pregnancy.
    The journal of obstetrics and gynaecology research, 2022, Volume: 48, Issue:12

    Topics: Amniotic Fluid; Cesarean Section; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Infant, Ne

2022
Graves' disease complicated by fetal goitrous hypothyroidism treated with intra-amniotic administration of levothyroxine.
    BMJ case reports, 2019, Aug-15, Volume: 12, Issue:8

    Topics: Drug Administration Routes; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hypothyroidism;

2019
Thyroid Hormone Deficiency Suppresses Fetal Pituitary-Adrenal Function Near Term: Implications for the Control of Fetal Maturation and Parturition.
    Thyroid : official journal of the American Thyroid Association, 2021, Volume: 31, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Medulla; Adrenocorticotropic Hormone; Animals; Cell

2021
Acquired Hypothyroidism in a Newborn Treated with Amiodarone in the First Week of Life.
    Indian pediatrics, 2017, 05-15, Volume: 54, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Fetal Diseases; Humans; Hypothyroidism; Infant, Newborn; Prenata

2017
Fetal goitrous hypothyroidism treated by intra-amniotic levothyroxine administration: case report and review of the literature.
    Journal of pediatric endocrinology & metabolism : JPEM, 2017, Aug-28, Volume: 30, Issue:9

    Topics: Adult; Antithyroid Agents; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hypothyroidism; P

2017
Iodine-Induced Fetal Hypothyroidism: Diagnosis and Treatment with Intra-Amniotic Levothyroxine.
    Hormone research in paediatrics, 2018, Volume: 90, Issue:6

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Iodine; Male; Pregnancy; P

2018
Foetal goitrous hypothyroidism - easy to recognise, difficult to treat. Is combined intra-amniotic and intravenous L-thyroxine therapy an option?
    Endokrynologia Polska, 2018, Volume: 69, Issue:4

    Topics: Cardiomegaly; Congenital Hypothyroidism; Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Inj

2018
Prenatal diagnosis and treatment perspective of fetal hypothyroidism with goiter.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:3

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Blood; Fetal Diseases; Gestational Age; Goiter; Huma

2013
Thyroid dysfunction in pregnancy: offspring effects.
    The lancet. Diabetes & endocrinology, 2013, Volume: 1, Issue:3

    Topics: Age Factors; Female; Fetal Diseases; Humans; Pregnancy; Pregnancy Complications; Thioamides; Thyroid

2013
50 years ago in the Journal of Pediatrics: Fetal hypothyroidism: I. Effects of hypothyroidism on neural development; II. Fetal versus maternal contributions to fetal thyroxine requirements; III. Clinical implications.
    The Journal of pediatrics, 2014, Volume: 164, Issue:4

    Topics: Female; Fetal Diseases; History, 20th Century; Humans; Hypothyroidism; Pediatrics; Periodicals as To

2014
Hyperthyroidism during pregnancy--the role of measuring maternal TSH receptor antibodies and foetal ultrasound monitoring.
    Endokrynologia Polska, 2014, Volume: 65, Issue:4

    Topics: Adult; Autoantibodies; Female; Fetal Diseases; Humans; Pregnancy; Pregnancy Complications; Prospecti

2014
A case of fetal hyperthyroidism treated with maternal administration of methimazole.
    Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:12

    Topics: Antithyroid Agents; Cordocentesis; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hyperthyr

2014
Favorable neurodevelopmental outcome in a hypothyroid neonate following intracordal amiodarone for cardioversion of refractory supraventricular tachycardia in a fetus.
    Journal of neonatal-perinatal medicine, 2014, Volume: 7, Issue:4

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Female; Fetal Diseases; Humans; Hydrops Fetalis; Hypothyr

2014
Foetal thyroid dysfunction: treat the mother first!
    Hormone research in paediatrics, 2015, Volume: 83, Issue:2

    Topics: Autoantibodies; Congenital Hypothyroidism; Female; Fetal Diseases; Graves Disease; Humans; Pregnancy

2015
Fetal Hyperthyroidism: Intrauterine Treatment with Carbimazole in Two Siblings.
    Indian journal of pediatrics, 2015, Volume: 82, Issue:10

    Topics: Adult; Antithyroid Agents; Carbimazole; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyroid

2015
Fetuses of Mothers with Thyroid Disease May Be at Higher Risk of Developing Supraventricular Tachycardia.
    American journal of perinatology, 2015, Volume: 32, Issue:13

    Topics: Adult; Arrhythmias, Cardiac; Atrial Premature Complexes; Echocardiography; Female; Fetal Diseases; G

2015
Maternal bisphenol A alters fetal endocrine system: Thyroid adipokine dysfunction.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 95

    Topics: Adipokines; Administration, Oral; Animals; Benzhydryl Compounds; Endocrine System; Enzyme-Linked Imm

2016
Fetal hypothyroidism induced by maternal anti-TSH receptor blocking antibodies and complicated by polyhydramnios despite the absence of goiter. Treatment by intra-amniotic injections of levothyroxine.
    Annales d'endocrinologie, 2017, Volume: 78, Issue:1

    Topics: Adult; Amnion; Amniotic Fluid; Female; Fetal Diseases; Gestational Age; Humans; Hypothyroidism; Immu

2017
Antenatal treatment of fetal goiter: a therapeutic challenge.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22, Issue:1

    Topics: Adult; Amniotic Fluid; Congenital Hypothyroidism; Female; Fetal Diseases; Fetal Therapies; Goiter; H

2009
Antenatal diagnosis and treatment of a dyshormonogenetic fetal goiter.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2009, Volume: 28, Issue:1

    Topics: Adolescent; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Thyroxine; Treatment Outcome; Ul

2009
Fetal treatment for early dyshormonogenetic goiter.
    Prenatal diagnosis, 2009, Volume: 29, Issue:5

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Hormone Replacement Therapy; Human

2009
[Iodine deficiency and pregnancy. Current situation].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:1

    Topics: Adult; Autoantibodies; Dietary Supplements; Drug Utilization; Embryonic Development; Female; Fetal B

2009
Experience with intraamniotic thyroxine treatment in nonimmune fetal goitrous hypothyroidism in 12 cases.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:10

    Topics: Amnion; Amniotic Fluid; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Hypothyro

2009
Non-immune goiter and hypothyroidism in a 19-week fetus: a plea for conservative treatment.
    The Journal of pediatrics, 2010, Volume: 156, Issue:6

    Topics: Adult; Amniotic Fluid; Congenital Hypothyroidism; Cordocentesis; Female; Fetal Diseases; Goiter; Hum

2010
Treatment of fetal goitrous hypothyroidism: value of direct intramuscular L-thyroxine therapy.
    Prenatal diagnosis, 2010, Volume: 30, Issue:9

    Topics: Adult; Antithyroid Agents; Cordocentesis; Female; Fetal Diseases; Goiter; Graves Disease; Hormone Re

2010
Intrauterine treatment of an infant with fetal goitre.
    Journal of pediatric endocrinology & metabolism : JPEM, 2010, Volume: 23, Issue:7

    Topics: Congenital Hypothyroidism; Fetal Diseases; Goiter; Humans; Infant, Newborn; Iodide Peroxidase; Male;

2010
Fetal goitrous hypothyroidism due to maternal thyroid stimulation-blocking antibody: a case report.
    Fetal diagnosis and therapy, 2010, Volume: 28, Issue:4

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Hormone Replacement Therapy; Human

2010
Graves' disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxine.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:1

    Topics: Adult; Antithyroid Agents; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hypothyroidism; I

2011
Discovery of a fetal goiter on prenatal ultrasound in women treated for Graves' disease: first, do no harm.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:8

    Topics: Antithyroid Agents; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hypothyroidism; Male; Pr

2011
A rare case of recurrent fetal goiter.
    Fetal diagnosis and therapy, 2012, Volume: 31, Issue:1

    Topics: Adult; Female; Fetal Diseases; Gestational Age; Goiter; Humans; Pregnancy; Thyroxine; Ultrasonograph

2012
Thyroid function in fetuses with down syndrome.
    Hormone research in paediatrics, 2012, Volume: 78, Issue:2

    Topics: Adult; Down Syndrome; Female; Fetal Diseases; Fetus; Humans; Hypothyroidism; Male; Pregnancy; Thyroi

2012
Intrauterine diagnosis and treatment of fetal goitrous hypothyroidism.
    The journal of obstetrics and gynaecology research, 2013, Volume: 39, Issue:3

    Topics: Adult; Female; Fetal Diseases; Fetal Therapies; Goiter; Humans; Hypothyroidism; Infant, Newborn; Mal

2013
Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:7

    Topics: Animals; Body Weight; Brain; Cell Movement; Cerebral Cortex; Female; Fetal Diseases; Hippocampus; Hy

2003
Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism.
    Clinical endocrinology, 2003, Volume: 58, Issue:5

    Topics: Adult; Brain Injuries; Cross-Sectional Studies; Female; Fetal Diseases; Humans; Hypothyroidism; Immu

2003
Graves' disease in pregnancy: prospective evaluation of a selective invasive treatment protocol.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:1

    Topics: Amniotic Fluid; Antithyroid Agents; Autoantibodies; Blood Specimen Collection; Female; Fetal Blood;

2003
Life before birth: effects of cortisol on future cardiovascular and metabolic function.
    Acta paediatrica (Oslo, Norway : 1992), 2003, Volume: 92, Issue:7

    Topics: Animals; Cardiovascular System; Embryonic and Fetal Development; Endothelins; Female; Fetal Blood; F

2003
FETAL HYPOTHYROIDISM. I. EFFECTS OF THYROXINE ON NEURAL DEVELOPMENT. II. FETAL VERSUS MATERNAL CONTRIBUTIONS TO FETAL THYROXINE REQUIREMENTS. III. CLINICAL IMPLICATIONS.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Brain; Embryology; Female; Fetal Diseases; Fetus; Humans; Hypothyroidism; Maternal-Fetal Exchange; N

1964
PLACENTAL TRANSMISSION OF DRUGS.
    Clinical proceedings - Children's Hospital of the District of Columbia, 1964, Volume: 20

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Barbiturates; Chloramph

1964
MANAGEMENT OF HYPOTHYROIDISM DURING INFANCY AND CHILDHOOD.
    Modern treatment, 1964, Volume: 1

    Topics: Adolescent; Alkaline Phosphatase; Antithyroid Agents; Body Height; Body Weight; Child; Cholesterol;

1964
Fetal loss associated with excess thyroid hormone exposure.
    JAMA, 2005, Jan-12, Volume: 293, Issue:2

    Topics: Abortion, Spontaneous; Birth Weight; Female; Fetal Development; Fetal Diseases; Humans; Hyperthyroid

2005
Intrauterine therapy of goitrous hypothyroidism in a boy with a new compound heterozygous mutation (Y453D and C800R) in the thyroid peroxidase gene. A long-term follow-up.
    American journal of obstetrics and gynecology, 2005, Volume: 193, Issue:3 Pt 1

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Fetal Therapies; Follow-Up Studies; Goiter

2005
[Correct procedure in the presence of a fetal goiter associated with hypothyroidism. Observations from three cases].
    Gynecologie, obstetrique & fertilite, 2006, Volume: 34, Issue:1

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Pregnancy; Pregnancy Outco

2006
Successful in utero treatment of fetal goitrous hypothyroidism: case report and review of the literature.
    Fetal diagnosis and therapy, 2006, Volume: 21, Issue:4

    Topics: Adult; Cordocentesis; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Infant, Newborn; Male;

2006
Prenatal diagnosis and early treatment of fetal goitrous hypothyroidism and treatment results with two-year follow-up.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2007, Volume: 20, Issue:3

    Topics: Adult; Child, Preschool; Congenital Hypothyroidism; Female; Fetal Diseases; Follow-Up Studies; Goite

2007
Successful intrauterine therapy for fetal goitrous hypothyroidism during late gestation.
    Endocrine journal, 2007, Volume: 54, Issue:5

    Topics: Adult; Amniotic Fluid; Antithyroid Agents; Congenital Hypothyroidism; Female; Fetal Diseases; Fetal

2007
Intrauterine fetal goiter: diagnosis and management.
    Taiwanese journal of obstetrics & gynecology, 2008, Volume: 47, Issue:1

    Topics: Adult; Cesarean Section; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Polyhydr

2008
Antenatal diagnosis and treatment of a fetal goiter.
    The Journal of reproductive medicine, 1980, Volume: 24, Issue:1

    Topics: Adult; Female; Fetal Diseases; Goiter; Goiter, Nodular; Humans; Lung; Maternal-Fetal Exchange; Polyh

1980
Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine.
    Endocrinology, 1982, Volume: 111, Issue:1

    Topics: Animals; Congenital Hypothyroidism; Dose-Response Relationship, Drug; Female; Fetal Diseases; Kineti

1982
Maternal thyroid function is the major determinant of amniotic fluid 3,3',5'-triiodothyronine in the rat.
    The Journal of clinical investigation, 1981, Volume: 67, Issue:4

    Topics: Amniotic Fluid; Animals; Female; Fetal Diseases; Hypothyroidism; Pregnancy; Pregnancy Complications;

1981
Behavioural sequelae of fetal iodine deficiency.
    Progress in clinical and biological research, 1981, Volume: 77

    Topics: Child, Preschool; Congenital Hypothyroidism; Double-Blind Method; Female; Fetal Diseases; Humans; In

1981
A simple model for studying the correction of in utero hypothyroidism in the rat.
    Pediatric research, 1995, Volume: 37, Issue:4 Pt 1

    Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Female; Fetal Diseases;

1995
Fetal hypothyroidism as a complication of amiodarone treatment for persistent fetal supraventricular tachycardia.
    Prenatal diagnosis, 1994, Volume: 14, Issue:8

    Topics: Adult; Amiodarone; Digoxin; Female; Fetal Diseases; Humans; Hypothyroidism; Infant, Newborn; Male; P

1994
Sulfate conjugates of iodothyronines in developing sheep: effect of fetal hypothyroidism.
    The American journal of physiology, 1993, Volume: 265, Issue:1 Pt 1

    Topics: Animals; Body Fluids; Fetal Diseases; Fetus; Hypothyroidism; Sheep; Sulfates; Thyroidectomy; Thyroni

1993
A study of the serum 3,5,3'-triiodothyronine sulfate concentration in normal and hypothyroid fetuses at various gestational stages.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:6

    Topics: Embryonic and Fetal Development; Female; Fetal Diseases; Gestational Age; Humans; Hypothyroidism; Ma

1993
In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil.
    Prenatal diagnosis, 1995, Volume: 15, Issue:7

    Topics: Adult; Dose-Response Relationship, Drug; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hyp

1995
In utero treatment of fetal goitrous hypothyroidism caused by maternal Graves' disease.
    American journal of perinatology, 1995, Volume: 12, Issue:6

    Topics: Adult; Female; Fetal Diseases; Graves Disease; Humans; Hypothyroidism; Pregnancy; Pregnancy Complica

1995
Regional blood flow and the endocrine response to sustained hypoxemia in the preterm ovine fetus.
    Pediatric research, 1996, Volume: 40, Issue:2

    Topics: Acidosis; Adrenocorticotropic Hormone; Animals; Cerebrovascular Circulation; Chronic Disease; Corona

1996
Liposomal thyroxine: a noninvasive model for transplacental fetal therapy.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:10

    Topics: Chromatography; Drug Carriers; Female; Fetal Diseases; Humans; In Vitro Techniques; Liposomes; Mater

1997
Effects of propylthiouracil and methimazole on fetal thyroid status in mothers with Graves' hyperthyroidism.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Female; Fetal Blood; Fetal Diseases; Graves Disease; Humans; Hypothyroidism; Maternal-Fetal Exchange

1997
Prenatal diagnosis and treatment of dyshormonogenetic fetal goiter due to defective thyroglobulin synthesis.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:12

    Topics: Adult; Female; Fetal Diseases; Goiter; Humans; Pedigree; Prenatal Diagnosis; Thyroglobulin; Thyroxin

1997
Diagnosis and treatment in utero of goiter with hypothyroidism caused by iodide overload.
    The Journal of pediatrics, 1998, Volume: 133, Issue:1

    Topics: Adult; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Potassium Iodide; Pregnancy; Thyroxin

1998
Prenatal diagnosis of thyroid hormone resistance.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:2

    Topics: Adult; DNA; Female; Fetal Blood; Fetal Diseases; Gestational Age; Heterozygote; Humans; Mutation; Pr

1999
Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.
    The New England journal of medicine, 1999, Aug-19, Volume: 341, Issue:8

    Topics: Adult; Case-Control Studies; Child; Child Language; Developmental Disabilities; Female; Fetal Diseas

1999
Fetal pituitary negative feedback at early gestational age.
    Clinical endocrinology, 1999, Volume: 50, Issue:6

    Topics: Adult; Amniotic Fluid; Feedback; Female; Fetal Blood; Fetal Diseases; Gestational Age; Graves Diseas

1999
Maternal compound W serial measurements for the management of fetal hypothyroidsm.
    European journal of endocrinology, 1999, Volume: 141, Issue:6

    Topics: Biomarkers; Cordocentesis; Diiodothyronines; Female; Fetal Blood; Fetal Diseases; Gestational Age; H

1999
Prenatal diagnosis and early in utero management of fetal dyshormonogenetic goiter.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 94, Issue:2

    Topics: Adult; Amniocentesis; Amniotic Fluid; Cesarean Section, Repeat; Female; Fetal Blood; Fetal Diseases;

2001
[Timely recognition and treatment of hypothyroidism in pregnant women: benefit for the child].
    Nederlands tijdschrift voor geneeskunde, 2001, Apr-14, Volume: 145, Issue:15

    Topics: Adult; Disease Management; Female; Fetal Diseases; Hormone Replacement Therapy; Humans; Hypothyroidi

2001
Transient fetal hypothyroidism due to direct fetal administration of amiodarone for drug resistant fetal tachycardia.
    American journal of perinatology, 2001, Volume: 18, Issue:2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Female; Fetal Diseases; Humans; Hypothyroidism; Infant, N

2001
Intrauterine diagnosis and management of congenital goitrous hypothyroidism.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2002, Volume: 19, Issue:5

    Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Fetal Diseases; Follow-Up Studies; Goiter; Humans; Hypot

2002
Antenatal diagnosis and treatment of a case of fetal goitrous hypothyroidism associated with high-output cardiac failure.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2002, Volume: 19, Issue:5

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Follow-Up Studies; Goiter; Heart Failure;

2002
[Basedow's disease in the pregnant woman. Should thyroxine be added to synthetic antithyroid drugs?].
    La Nouvelle presse medicale, 1976, Oct-02, Volume: 5, Issue:32

    Topics: Antithyroid Agents; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Maternal-Fetal Exchange;

1976
Fetal thyrotoxicosis in utero.
    Biology of the neonate, 1979, Volume: 35, Issue:3-4

    Topics: Female; Fetal Diseases; Humans; Hyperkinesis; Hyperthyroidism; Infant, Newborn; Long-Acting Thyroid

1979
Screening for neonatal hypothyroidism.
    British journal of hospital medicine, 1979, Volume: 21, Issue:1

    Topics: Congenital Hypothyroidism; Female; Fetal Diseases; Fetal Monitoring; Humans; Hypothyroidism; Infant;

1979
New approaches to some thyroid problems.
    The Medical journal of Australia, 1979, Jul-28, Volume: 2, Issue:2

    Topics: Carbimazole; Female; Fetal Diseases; Humans; Infant, Newborn; Long-Acting Thyroid Stimulator; Matern

1979
Hyperthyroidism during pregnancy treated with propylthiouracil. The significance of maternal and foetal parameters.
    Acta obstetricia et gynecologica Scandinavica, 1977, Volume: 56, Issue:5

    Topics: Adult; Female; Fetal Diseases; Fetal Heart; Heart Rate; Humans; Hyperthyroidism; Infant, Newborn; Lo

1977
Intra-amniotic injection of thyroxine (T4Y to a human fetus. Evidence for conversion of T4 to reverse T3.
    American journal of obstetrics and gynecology, 1977, Mar-01, Volume: 127, Issue:5

    Topics: Adult; Amnion; Amniotic Fluid; Female; Fetal Diseases; Humans; Hypothyroidism; Infant, Newborn; Inje

1977
Intra-uterine treatment of a hypothyroid fetus.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:3

    Topics: Adult; Female; Fetal Diseases; Humans; Hypothyroidism; Maternal-Fetal Exchange; Pregnancy; Pregnancy

1975
Thyroid hormones and thyrotropin in amniotic fluid.
    The New England journal of medicine, 1975, Oct-09, Volume: 293, Issue:15

    Topics: Amniotic Fluid; Female; Fetal Diseases; Gestational Age; Humans; Isomerism; Pregnancy; Prenatal Diag

1975
Experimental cretinism in lambs: an intrauterine model with thyroid evaluation in surviving lambs.
    The Johns Hopkins medical journal, 1975, Volume: 137, Issue:3

    Topics: Amniotic Fluid; Animals; Congenital Hypothyroidism; Disease Models, Animal; Female; Fetal Diseases;

1975
Failure of triiodothyronine to prevent propylthiouracil-induced hypothyroidism and goiter in fetal sheep.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Fetal Diseases; Goiter; Hypothyroidism; Organ Size; Pregnan

1976
Thyroid dysfunction in utero.
    Lancet (London, England), 1992, Jan-18, Volume: 339, Issue:8786

    Topics: Female; Fetal Blood; Fetal Diseases; Humans; Hypothyroidism; Pregnancy; Prenatal Diagnosis; Thyroid

1992
Early prenatal diagnosis and therapy of fetal hypothyroid goiter.
    Fetal diagnosis and therapy, 1992, Volume: 7, Issue:2

    Topics: Adult; Amniotic Fluid; Congenital Hypothyroidism; Female; Fetal Diseases; Goiter; Humans; Hypothyroi

1992
Successful in utero treatment of fetal goiter and hypothyroidism.
    The New England journal of medicine, 1991, Feb-21, Volume: 324, Issue:8

    Topics: Adult; Amnion; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hypothyroidism; Injections; P

1991
Thyroid function in fetuses with chromosomal abnormalities.
    BMJ (Clinical research ed.), 1991, Mar-16, Volume: 302, Issue:6777

    Topics: Chromosome Aberrations; Chromosome Disorders; Fetal Blood; Fetal Diseases; Gestational Age; Humans;

1991
Thyroid function in anemic fetuses.
    Fetal diagnosis and therapy, 1990, Volume: 5, Issue:3-4

    Topics: Anemia; Fetal Blood; Fetal Diseases; Gestational Age; Humans; Rh Isoimmunization; Thyroid Gland; Thy

1990
Intrauterine diagnosis and treatment of fetal goitrous hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:3

    Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Fetal Diseases; Goiter, Nodular; Humans; Hypothyroidism;

1990
Congenital hereditary hypothyroidism--prenatal diagnosis and treatment.
    Prenatal diagnosis, 1990, Volume: 10, Issue:8

    Topics: Amniotic Fluid; Congenital Hypothyroidism; Female; Fetal Diseases; Humans; Hypothyroidism; Pregnancy

1990
Antithyroid drug therapy for Graves' disease during pregnancy. Optimal regimen for fetal thyroid status.
    The New England journal of medicine, 1986, Jul-03, Volume: 315, Issue:1

    Topics: Antibodies; Antithyroid Agents; Female; Fetal Blood; Fetal Diseases; Fetus; Graves Disease; Humans;

1986
Fetal goitrous hypothyroidism. A new diagnostic and therapeutic approach.
    Fetal therapy, 1989, Volume: 4, Issue:2-3

    Topics: Adult; Female; Fetal Blood; Fetal Diseases; Goiter; Humans; Hypothyroidism; Polyhydramnios; Pregnanc

1989
Recovery from foetal hypothyroidism: evidence for the safety of breast-feeding while taking propylthiouracil.
    Clinical endocrinology, 1989, Volume: 31, Issue:5

    Topics: Adult; Breast Feeding; Female; Fetal Diseases; Graves Disease; Humans; Hypothyroidism; Infant, Newbo

1989
Regulation of neonatal heart glycogen metabolism by thyroxine.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:4

    Topics: Animals; Animals, Newborn; Blood Glucose; Congenital Hypothyroidism; Female; Fetal Diseases; Glycoge

1986
Amniotic fluid thyrotropin (TSH) following maternal administration of thyrotropin releasing hormone.
    Journal of perinatal medicine, 1985, Volume: 13, Issue:5

    Topics: Amniotic Fluid; Delivery, Obstetric; Female; Fetal Blood; Fetal Diseases; Humans; Hypothyroidism; In

1985
Thyroxine derivatives in amniotic fluid. Fetal outcome in three patients with thyroid problems.
    The Journal of pediatrics, 1971, Volume: 79, Issue:6

    Topics: Adult; Amniocentesis; Amniotic Fluid; Female; Fetal Diseases; Graves Disease; Humans; Hypothyroidism

1971
Hyperthyroidism and pregnancy.
    The Journal of reproductive medicine, 1972, Volume: 8, Issue:2

    Topics: Antithyroid Agents; Female; Fetal Diseases; Fetus; Graves Disease; Humans; Hyperthyroidism; Infant,

1972
Letter: Congenital deafness and hypothyroidism.
    Lancet (London, England), 1974, May-11, Volume: 1, Issue:7863

    Topics: Deafness; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Maternal-Fetal Exchange; Pregnancy

1974
Role of the placenta and of plasma hormone binding in the pathogenesis of cretinism.
    Advances in experimental medicine and biology, 1972, Volume: 30

    Topics: Congenital Hypothyroidism; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Pregnancy; Pregn

1972
Prenatal hypothyroidism and brain composition in a primate.
    Nature, 1973, Jun-15, Volume: 243, Issue:5407

    Topics: Animals; Body Water; Brain; Brain Chemistry; Carbonic Anhydrases; Chlorides; Disease Models, Animal;

1973
The effects of Renografin-60 on the fetal thyroid.
    Obstetrics and gynecology, 1973, Volume: 42, Issue:1

    Topics: Amniotic Fluid; Birth Weight; Delivery, Obstetric; Diatrizoate; Female; Fetal Diseases; Goiter; Huma

1973
[Treatment of thyrotoxicosis in pregnancy].
    Nordisk medicin, 1968, Apr-11, Volume: 79, Issue:15

    Topics: Congenital Hypothyroidism; Female; Fetal Diseases; Humans; Hyperthyroidism; Infant, Newborn; Materna

1968