thyroxine has been researched along with Dwarfism, Growth Hormone Deficiency in 79 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recombinant hGH treatment may alter thyroid hormone metabolism and we have recently reported that 50% of patients with GH deficiency (GHD) due to organic lesions, previously not treated with thyroxine, developed hypothyroidism during treatment with recombinant human GH (rhGH)." | 5.10 | Recombinant hGH replacement therapy and the hypothalamus-pituitary-thyroid axis in children with GH deficiency: when should we be concerned about the occurrence of central hypothyroidism? ( Arosio, M; Beck-Peccoz, P; Cappiello, V; Epaminonda, P; Ferrante, E; Giavoli, C; Porretti, S; Ronchi, CL; Travaglini, P, 2003) |
| ", mouse with Snell pituitary dwarfism (dw) in which hypoplasia of the pituitary anterior lobe is seen from embryonal stage and which almost lacks in growth hormone (GH), prolactin (PRL), thyroid stimulating hormone (TSH) and adrenocorticotrophic hormone (ACTH); mouse with little dwarfism lacking only in GH (lit); and mouse with congenital primary hypothyroidism in which the thyroidal gland shows hypoplasia, thyroxine (T4) in blood is not measurable and, conversely, TSH level is abnormally high (hyt), the males of dw/dw and hyt/hyt have been proved to be infertile, but it is little known about lit/lit." | 3.67 | [Study on testicular tissue in animals with congenital hormone deficiency]. ( Kuroda, K, 1989) |
| " nutriments, and hypothyroidism on the peripheral conversion of thyroxine (T4) to 3,3', 5-triiodothyronine (T3) in the rat and mouse, an in vitro system for assessing T4 conversion to T3 by fresh liver homogenates was used." | 3.66 | Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat. ( Braverman, LE; Fang, SL; Harris, AR; Vagenakis, AG, 1978) |
| " In 4 cases in Group II, the plasma cortisol level increased 120 min after the infusion of lysine-vasopressin, whereas oral administration of metyrapone and hypoglycemia induced by insulin did not increase the plasma cortisol levels." | 3.66 | Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism. Further evidence for hypophysiotropic human deficiencies. ( Harada, T; Iida, Y; Kai, H; Miyai, K; Nose, O; Okada, S; Yabuuchi, H, 1978) |
| "In German shepherd dogs pituitary dwarfism is known as an autosomal recessive inherited abnormality." | 1.31 | Combined pituitary hormone deficiency in german shepherd dogs with dwarfism. ( Kooistra, HS; Mol, JA; Rijnberk, A; Voorhout, G, 2000) |
| "A patient with isolated GH deficiency received 0." | 1.27 | Effects of human pancreatic tumour growth hormone releasing factor on growth hormone and somatomedin C levels in patients with idiopathic growth hormone deficiency. ( Blizzard, RM; Borges, JL; Evans, WS; Furlanetto, R; Gelato, MC; Kaiser, DL; Loriaux, DL; MacLeod, RM; Merriam, GR; Rivier, J; Rogol, AD; Spiess, J; Thorner, MO; Vale, W; Vance, ML, 1983) |
| " hGRF was therefore administered at a dosage of 100 micrograms twice a day subcutaneously for three months." | 1.27 | Effects of hGRF treatment of a patient with hGRF deficiency. ( Hizuka, N; Shizume, K; Takano, K; Tanaka, I, 1985) |
| "Pituitary dwarfism has been described in more than 20 German shepherd dogs." | 1.26 | [Pituitary dwarfism in a German shepherd dog (author's transl)]. ( El Etreby, MF; Müller-Peddinghaus, R; Ranke, M; Siefert, J, 1980) |
| " As a control group, six patients with primary hypothyroidism received gradually increasing doses of L-T4 for 4-week periods, and TSH response to TRH was tested at the end of each dosage of L-T4, until complete inhibition of TSH release was obtained." | 1.26 | Low setting of feedback regulation of TSH secretion by thyroxine in pituitary dwarfism with TSH-releasing hormone deficiency. ( Ishiguro, K; Isumisawa, A; Sato, T; Suzuki, Y; Taketani, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (73.42) | 18.7374 |
| 1990's | 8 (10.13) | 18.2507 |
| 2000's | 5 (6.33) | 29.6817 |
| 2010's | 7 (8.86) | 24.3611 |
| 2020's | 1 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Kitzmann, S | 1 |
| Hartmann, K | 1 |
| Zablotski, Y | 1 |
| Rieger, A | 1 |
| Mueller, R | 1 |
| Wehner, A | 1 |
| Keskin, M | 1 |
| Bayramoglu, E | 1 |
| Aycan, Z | 1 |
| Yamauchi, I | 1 |
| Sakane, Y | 1 |
| Yamashita, T | 1 |
| Hirota, K | 1 |
| Ueda, Y | 1 |
| Kanai, Y | 1 |
| Yamashita, Y | 1 |
| Kondo, E | 1 |
| Fujii, T | 1 |
| Taura, D | 1 |
| Sone, M | 1 |
| Yasoda, A | 1 |
| Inagaki, N | 1 |
| Lass, N | 1 |
| Reinehr, T | 1 |
| Valsesia, A | 1 |
| Chatelain, P | 1 |
| Stevens, A | 1 |
| Peterkova, VA | 1 |
| Belgorosky, A | 1 |
| Maghnie, M | 1 |
| Antoniazzi, F | 1 |
| Koledova, E | 1 |
| Wojcik, J | 1 |
| Farmer, P | 1 |
| Destenaves, B | 1 |
| Clayton, P | 1 |
| De Bellis, A | 1 |
| Bellastella, G | 1 |
| Maiorino, MI | 1 |
| Aitella, E | 1 |
| Lucci, E | 1 |
| Cozzolino, D | 1 |
| Bellastella, A | 1 |
| Bizzarro, A | 1 |
| Giugliano, D | 1 |
| Esposito, K | 1 |
| Losa, M | 1 |
| Scavini, M | 1 |
| Gatti, E | 1 |
| Rossini, A | 1 |
| Madaschi, S | 1 |
| Formenti, I | 1 |
| Caumo, A | 1 |
| Stidley, CA | 1 |
| Lanzi, R | 1 |
| Louvel, M | 1 |
| Marcu, M | 1 |
| Trivin, C | 1 |
| Souberbielle, JC | 1 |
| Brauner, R | 1 |
| Zhang, H | 1 |
| Wang, Y | 1 |
| Han, L | 1 |
| Gu, X | 1 |
| Shi, D | 1 |
| Hokken-Koelega, AC | 1 |
| BIELSCHOWSKY, F | 1 |
| BIELSCHOWSKY, M | 1 |
| FLETCHER, EK | 1 |
| TRYGSTAD, O | 2 |
| SEIP, M | 2 |
| NIELSEN, EL | 1 |
| Giavoli, C | 1 |
| Porretti, S | 1 |
| Ferrante, E | 1 |
| Cappiello, V | 1 |
| Ronchi, CL | 1 |
| Travaglini, P | 1 |
| Epaminonda, P | 1 |
| Arosio, M | 1 |
| Beck-Peccoz, P | 1 |
| Donaldson, D | 1 |
| Billson, FM | 1 |
| Scase, TJ | 1 |
| Sparkes, AH | 1 |
| McConnell, F | 1 |
| Mould, JR | 1 |
| Adams, V | 1 |
| Newns, GH | 1 |
| Borges, JL | 1 |
| Blizzard, RM | 1 |
| Gelato, MC | 1 |
| Furlanetto, R | 1 |
| Rogol, AD | 1 |
| Evans, WS | 1 |
| Vance, ML | 1 |
| Kaiser, DL | 1 |
| MacLeod, RM | 1 |
| Merriam, GR | 1 |
| Loriaux, DL | 1 |
| Spiess, J | 1 |
| Rivier, J | 1 |
| Vale, W | 1 |
| Thorner, MO | 1 |
| van Buul-Offers, S | 4 |
| Van den Brande, JL | 3 |
| Müller-Peddinghaus, R | 1 |
| El Etreby, MF | 1 |
| Siefert, J | 1 |
| Ranke, M | 1 |
| Takano, K | 2 |
| Sato, T | 3 |
| Kajiwara, S | 1 |
| Miyamori, C | 1 |
| Kato, T | 1 |
| Hackeng, WH | 2 |
| Schopman, W | 1 |
| Garnier, PE | 1 |
| Roger, M | 1 |
| Chaussain, JL | 1 |
| Canlorbe, P | 1 |
| Job, JC | 1 |
| Sobieszczyk, S | 1 |
| Polańska, A | 1 |
| Kosowicz, J | 1 |
| Smeets, T | 1 |
| Ashton, IK | 1 |
| Dekel, S | 1 |
| Demura, R | 1 |
| Yamaguchi, H | 1 |
| Wakabayashi, I | 1 |
| Demura, H | 1 |
| Shizume, K | 2 |
| Gruñeiro de Papendieck, L | 1 |
| Iorcansky, S | 1 |
| Rivarola, MA | 1 |
| Heinrich, JJ | 1 |
| Bergadá, C | 1 |
| Holder, AT | 3 |
| Wallis, M | 3 |
| Biggs, P | 1 |
| Preece, MA | 1 |
| Tokuda, N | 1 |
| Shibayama, K | 1 |
| Ohyama, Y | 1 |
| Ono, M | 1 |
| Furudate, S | 1 |
| Wilson, DB | 1 |
| Wyatt, DP | 1 |
| Umezu, M | 1 |
| Fujimura, T | 1 |
| Sugawara, S | 1 |
| Kagabu, S | 1 |
| Ramsey, IK | 1 |
| Evans, H | 1 |
| Herrtage, ME | 1 |
| Kooistra, HS | 1 |
| Voorhout, G | 1 |
| Mol, JA | 1 |
| Rijnberk, A | 1 |
| Harris, AR | 1 |
| Fang, SL | 1 |
| Vagenakis, AG | 1 |
| Braverman, LE | 1 |
| Lippe, BM | 1 |
| Van Herle, AJ | 1 |
| LaFranchi, SH | 1 |
| Uller, RP | 1 |
| Lavin, N | 1 |
| Kaplan, SA | 1 |
| Knazek, RA | 1 |
| Liu, SC | 1 |
| Gullino, PM | 1 |
| Suzukui, Y | 1 |
| Taketani, T | 2 |
| Ishiguro, K | 2 |
| Masuyama, T | 1 |
| Nose, O | 1 |
| Iida, Y | 1 |
| Kai, H | 1 |
| Harada, T | 1 |
| Okada, S | 1 |
| Yabuuchi, H | 1 |
| Miyai, K | 1 |
| Hesse, V | 1 |
| Daughaday, WH | 1 |
| Herington, AC | 1 |
| Phillips, LS | 1 |
| Suzuki, Y | 1 |
| Isumisawa, A | 1 |
| Ishihara, M | 1 |
| Wada, K | 1 |
| Nakaya, T | 1 |
| Yamawaki, M | 1 |
| Matsumoto, Y | 1 |
| Andler, W | 1 |
| Heüveldop, A | 1 |
| Polichronidou, T | 1 |
| Noguchi, T | 1 |
| Randolph, JF | 1 |
| Miller, CL | 1 |
| Cummings, JF | 1 |
| Lothrop, CD | 1 |
| Wit, JM | 1 |
| Drayer, NM | 1 |
| Jansen, M | 1 |
| Walenkamp, MJ | 1 |
| Thijssen, JH | 1 |
| Kuroda, K | 1 |
| Webb, SM | 1 |
| Lewiński, AK | 1 |
| Steger, RW | 1 |
| Reiter, RJ | 1 |
| Bartke, A | 2 |
| Eiholzer, U | 1 |
| Zachmann, M | 1 |
| Gnehm, HE | 1 |
| Prader, A | 1 |
| Bates, PC | 1 |
| Fabris, N | 4 |
| Mocchegiani, E | 1 |
| Muzzioli, M | 1 |
| Provinciali, M | 1 |
| van Buul, PP | 1 |
| van Buul-Offers, SC | 1 |
| Hizuka, N | 1 |
| Tanaka, I | 1 |
| Whalen, RG | 1 |
| Toutant, M | 1 |
| Butler-Browne, GS | 1 |
| Watkins, SC | 1 |
| Horiguchi, T | 1 |
| Cacciari, E | 1 |
| Bernardi, F | 1 |
| Salardi, S | 1 |
| Tassoni, P | 1 |
| Cicognani, A | 1 |
| Pirazzoli, P | 1 |
| Zappulla, F | 1 |
| Zingoni, S | 1 |
| Harrison, MR | 1 |
| Fierro-Benitez, R | 1 |
| Ramirez, I | 1 |
| Refetoff, S | 2 |
| Stanbury, JB | 1 |
| Costom, BH | 1 |
| Grumbach, MM | 1 |
| Kaplan, SL | 1 |
| Clot, JP | 1 |
| Baudry, M | 1 |
| Michel, R | 1 |
| Baroni, CD | 2 |
| Doria, G | 1 |
| Pierpaoli, W | 2 |
| Sorkin, E | 2 |
| Gual, C | 1 |
| Kastin, AJ | 1 |
| Schally, AV | 1 |
| Porter, BA | 1 |
| Rosenfeld, RL | 1 |
| De Groat, LJ | 1 |
| Lang, US | 1 |
| Stark, O | 1 |
| Dew, JA | 1 |
| Tunbridge, WM | 1 |
| Marshall, JC | 1 |
| Burke, CW | 1 |
| Goolamali, SK | 1 |
| Burton, JL | 1 |
| Shuster, S | 1 |
| Frasier, SD | 1 |
| Aceto, T | 1 |
| Hayles, AB | 1 |
| Parker, ML | 1 |
| Meyer-Bahlburg, HF | 1 |
| Hall, K | 1 |
| Olin, P | 1 |
| Escamilla, RF | 1 |
| Forsham, PH | 1 |
| Tanner, JM | 1 |
| Whitehouse, RH | 1 |
| Hughes, PC | 1 |
| Vince, FP | 1 |
| Schwenk, A | 1 |
| Geisen, K | 1 |
| Baroni, C | 1 |
| Bertoli, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Observational Long-term Follow-up of the Phase IV Open-label Trial of Predictive Markers in GHD and TS Pre-pubertal Children Treated With Saizen[NCT00699855] | 182 participants (Actual) | Observational | 2008-09-30 | Completed | |||
| A Phase IV Open-label Study of Predictive Markers in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children Treated With SAIZEN®[NCT00256126] | Phase 4 | 318 participants (Actual) | Interventional | 2005-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | Units per liter (U/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 21.13 |
| Growth Hormone Deficiency (GHD) | 14.78 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | millimoles per liter (mmol/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 0.22 |
| Growth Hormone Deficiency (GHD) | 0.13 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | picomole per liter (pmol/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 47.7 |
| Growth Hormone Deficiency (GHD) | 26.9 |
HOMA-IR is used to assess insulin resistance and calculated by an empirical mathematical formula based on fasting plasma glucose and fasting plasma insulin levels. HOMA-IR = fasting plasma insulin (picomole/liter [pmol/L]) * fasting plasma glucose (millimole/liter [mmol/L]) divided by 22.5. (NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | picomole per liter *millimole per liter (Mean) |
|---|---|
| Turner Syndrome (TS) | 2.132 |
| Growth Hormone Deficiency (GHD) | 1.061 |
IGF-1 SDS was calculated using the Elmlinger reference method. Change in within subject IGF-1 levels (standard deviation scores) at Month 1 from Baseline was assessed. Descriptive statistics were determined for the Baseline and Month 1 assessments, and also for the level of change between these two assessments. If either the Baseline or Month 1 IGF-1 level was missing, then the within-subject change in IGF-1 was assumed to be missing. (NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | Standard deviation score (SDS) (Mean) |
|---|---|
| Turner Syndrome (TS) | 1.7692 |
| Growth Hormone Deficiency (GHD) | 1.4007 |
(NCT00256126)
Timeframe: Baseline, Month 1
| Intervention | milligram per liter (mg/L) (Mean) |
|---|---|
| Turner Syndrome (TS) | 0.86 |
| Growth Hormone Deficiency (GHD) | 0.69 |
6 reviews available for thyroxine and Dwarfism, Growth Hormone Deficiency
| Article | Year |
|---|---|
[Experimental and clinical studies on somatomedin].
Topics: Acromegaly; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Animals; Child; Child, Preschoo | 1982 |
[Endocrine dwarfism. 2. Treatment of hypothalamo-hypophyseal dwarfism and of constitutional dwarfism with postponement of puberty].
Topics: Adrenal Cortex Hormones; Age Factors; Child; Craniopharyngioma; Dwarfism; Dwarfism, Pituitary; Femal | 1975 |
The regulation of growth by endocrines.
Topics: Adrenal Cortex Hormones; Animals; Body Weight; Cartilage; Dwarfism, Pituitary; Endocrine Glands; Glu | 1975 |
Retarded cerebral growth of hormone-deficient mice.
Topics: Animals; Brain; Dwarfism, Pituitary; Growth Hormone; Hypothyroidism; Mice; Mice, Mutant Strains; Mye | 1991 |
Neuroendocrine-thymus interactions: perspectives for intervention in aging.
Topics: Aging; Animals; Disease Models, Animal; Dwarfism, Pituitary; Humans; Immune System; Immunologic Defi | 1988 |
Clinical experience with hypothalamic releasing hormones. 1. Thyrotropin-releasing hormone.
Topics: Acromegaly; Adult; Amenorrhea; Craniopharyngioma; Dwarfism, Pituitary; Female; Humans; Hyperthyroidi | 1972 |
1 trial available for thyroxine and Dwarfism, Growth Hormone Deficiency
| Article | Year |
|---|---|
Recombinant hGH replacement therapy and the hypothalamus-pituitary-thyroid axis in children with GH deficiency: when should we be concerned about the occurrence of central hypothyroidism?
Topics: Adolescent; Child; Dwarfism, Pituitary; Female; Follow-Up Studies; Growth Hormone; Humans; Hypothala | 2003 |
72 other studies available for thyroxine and Dwarfism, Growth Hormone Deficiency
| Article | Year |
|---|---|
Wellbeing, quality of life, presence of concurrent diseases, and survival times in untreated and treated German Shepherd dogs with dwarfism.
Topics: Animals; Body Size; Case-Control Studies; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Growth Ho | 2021 |
Effects of 1-year growth hormone replacement therapy on thyroid volume and function of the children and adolescents with idiopathic growth hormone deficiency.
Topics: Adolescent; Case-Control Studies; Child; Dwarfism, Pituitary; Female; Follow-Up Studies; Hormone Rep | 2017 |
Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.
Topics: Acromegaly; Adult; Cell Line; Dwarfism, Pituitary; Female; Gene Expression Regulation; Hormone Repla | 2018 |
Low Treatment Adherence in Pubertal Children Treated with Thyroxin or Growth Hormone.
Topics: Adolescent; Child; Congenital Hypothyroidism; Dwarfism, Pituitary; Female; Hormone Replacement Thera | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
GH deficiency status combined with GH receptor polymorphism affects response to GH in children.
Topics: Blood Glucose; Body Height; Child; Cholesterol, HDL; Cholesterol, LDL; Dwarfism, Pituitary; Exons; F | 2015 |
Longitudinal behavior of autoimmune GH deficiency: from childhood to transition age.
Topics: Adolescent; Adrenocorticotropic Hormone; Autoantibodies; Autoimmune Hypophysitis; Child; Dwarfism, P | 2016 |
Long-term effects of growth hormone replacement therapy on thyroid function in adults with growth hormone deficiency.
Topics: Adult; Child; Dwarfism, Pituitary; Female; Follow-Up Studies; Hormone Replacement Therapy; Human Gro | 2008 |
Diagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency.
Topics: Adolescent; Body Height; Child; Child, Preschool; Drug Therapy, Combination; Dwarfism, Pituitary; Fe | 2009 |
A large deletion of PROP1 gene in patients with combined pituitary hormone deficiency from two unrelated Chinese pedigrees.
Topics: Adolescent; China; DNA; Dwarfism, Pituitary; Female; Gene Deletion; Genetic Variation; Homeodomain P | 2010 |
Diagnostic workup of the short child.
Topics: Blood Chemical Analysis; Body Height; Child; Child, Preschool; Dwarfism, Pituitary; Female; Growth D | 2011 |
Investigations on the role of thyroxine in the development of hepatomas in hypophysectomized rats and pituitary dwarf mice.
Topics: Animals; Carcinoma, Hepatocellular; Dwarfism; Dwarfism, Pituitary; Hypophysectomy; Liver Neoplasms; | 1962 |
HEREDITARY PITUITARY DWARFISM TREATED WITH HUMAN GROWTH HORMONE.
Topics: Adolescent; Child; Drug Therapy; Dwarfism; Dwarfism, Pituitary; Genetics, Medical; Growth Hormone; H | 1964 |
Studies on hereditary dwarfism in mice. XIII. Effect of the growth hormone and thyroxin on the growth of bones in mice with hereditary pituitary dwarfism.
Topics: Animals; Dwarfism; Dwarfism, Pituitary; Growth Hormone; Hormones; Human Growth Hormone; Mice; Pituit | 1952 |
Congenital hyposomatotropism in a domestic shorthair cat presenting with congenital corneal oedema.
Topics: Animals; Cat Diseases; Cats; Corneal Edema; Dwarfism, Pituitary; Female; Immunohistochemistry; Insul | 2008 |
Hypopituitary dwarfism.
Topics: Adolescent; Adult; Child; Child, Preschool; Cortisone; Craniopharyngioma; Dwarfism, Pituitary; Growt | 1967 |
Effects of human pancreatic tumour growth hormone releasing factor on growth hormone and somatomedin C levels in patients with idiopathic growth hormone deficiency.
Topics: Adult; Dwarfism, Pituitary; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Histiocytosis, | 1983 |
Cellular growth in organs of dwarf mice during treatment with growth hormone, thyroxine and plasma fractions containing somatomedin activity.
Topics: Animals; Cell Division; DNA; Dwarfism, Pituitary; Female; Growth Hormone; Kidney; Liver; Male; Mice; | 1982 |
[Pituitary dwarfism in a German shepherd dog (author's transl)].
Topics: Adrenocorticotropic Hormone; Animals; Atrophy; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Grow | 1980 |
Na-K-dependent ATPase in red cells and thyroid status.
Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Dwarfism; Dwarfism, Pituitary; Eryth | 1982 |
Thyroxine and triiodothyronine levels in Snell mice.
Topics: Animals; Dwarfism, Pituitary; Female; Hormones; Humans; Male; Mice; Mice, Inbred Strains; Thyroxine; | 1983 |
Prolactin and thyrotrophin responses to thyroliberin (TRH) in patients with growth hormone deficiency: study in 167 patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Dwarfism, Pituitary; Female; Growth Hormone; Humans; Hyp | 1983 |
[Serum thyroxine, triiodothyronine and reverse triiodothyronine concentrations in patients with pituitary dwarfism].
Topics: Adolescent; Adult; Child; Dwarfism, Pituitary; Female; Humans; Male; Thyroxine; Triiodothyronine; Tr | 1984 |
The influence of growth hormone, somatomedins, prolactin and thyroxine on the morphology of the proximal tibial epiphysis and growth plate of Snell dwarf mice.
Topics: Animals; Dwarfism, Pituitary; Epiphyses; Growth Hormone; Hormones; Mice; Osteogenesis; Prolactin; So | 1983 |
Fracture repair in the Snell dwarf mouse.
Topics: Animals; Body Weight; Dwarfism, Pituitary; Growth Hormone; Mice; Mice, Mutant Strains; Radiography; | 1983 |
The effect of hGH on hypothalamic-pituitary-thyroid function in patients with pituitary dwarfism.
Topics: Dwarfism, Pituitary; Growth Hormone; Half-Life; Humans; Hypothalamo-Hypophyseal System; Thyroid Func | 1980 |
Patterns of TSH response to TRH in children with hypopituitarism.
Topics: Adolescent; Child; Child, Preschool; Dwarfism, Pituitary; Female; Growth Hormone; Humans; Male; Thyr | 1982 |
Effects of growth hormone, prolactin and thyroxine on body wegith, somatomedin-like activity and in-vivo sulphation of cartilage in hypopituitary dwarf mice.
Topics: Animals; Body Weight; Cartilage; Dose-Response Relationship, Drug; Dwarfism, Pituitary; Female; Grow | 1980 |
[Effect of growth hormone and thyroxine on renal development in Snell pituitary dwarf mice].
Topics: Animals; DNA; Dwarfism, Pituitary; Female; Growth Hormone; Insulin-Like Growth Factor I; Kidney; Mal | 1995 |
Expression of mRNA coding for pituitary hormones and pituitary-specific transcription factor in the pituitary gland of the rdw rat with hereditary dwarfism.
Topics: Animals; Blotting, Northern; DNA-Binding Proteins; Dwarfism, Pituitary; Growth Hormone; Pituitary Gl | 1993 |
Immunocytochemical effects of thyroxine stimulation on the adenohypophysis of dwarf (dw) mutant mice.
Topics: Adrenocorticotropic Hormone; Animals; Chorionic Gonadotropin; Crosses, Genetic; Dwarfism, Pituitary; | 1993 |
Pituitary and serum levels of prolactin (PRL), thyroid stimulating hormone (TSH) and serum thyroxine (T4) in hereditary dwarf rats (rdw/rdw).
Topics: Animals; Disease Models, Animal; Dwarfism, Pituitary; Female; Male; Mutation; Pituitary Gland; Prola | 1993 |
Thyroid-stimulating hormone and total thyroxine concentrations in euthyroid, sick euthyroid and hypothyroid dogs.
Topics: Animals; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Hypothyroidism; Male; Radioimmunoassay; Re | 1997 |
Combined pituitary hormone deficiency in german shepherd dogs with dwarfism.
Topics: Adrenocorticotropic Hormone; Animals; Creatinine; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; F | 2000 |
Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat.
Topics: Amino Acids; Animals; Blood Glucose; Diet; Dietary Carbohydrates; Dwarfism, Pituitary; Hydrogen-Ion | 1978 |
Reversible hypothyroidism in growth hormone-deficient children treated with human growth hormone.
Topics: Age Determination by Skeleton; Body Height; Craniopharyngioma; Diabetes Insipidus; Dwarfism, Pituita | 1975 |
Induction of lactogenic binding sites in the liver of the Snell dwarf mouse.
Topics: Animals; Body Weight; Dwarfism, Pituitary; Female; Growth Hormone; Homozygote; Liver; Male; Mice; Pi | 1977 |
Enhanced peripheral conversion of thyroxine to triiodothyronine during hGH therapy in GH deficient children.
Topics: Adolescent; Adult; Body Height; Child; Child, Preschool; Dwarfism, Pituitary; Growth Hormone; Humans | 1977 |
Effect of growth hormone and peptide fractions containing somatomedin activity on growth and cartilage metabolism of Snell dwarfmice.
Topics: Animals; Blood Glucose; Body Weight; Cartilage; Dwarfism, Pituitary; Growth; Growth Hormone; Insulin | 1979 |
Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism. Further evidence for hypophysiotropic human deficiencies.
Topics: Adolescent; Child; Dwarfism, Pituitary; Female; Gonadotropins; Growth Hormone; Humans; Hydrocortison | 1978 |
Low setting of feedback regulation of TSH secretion by thyroxine in pituitary dwarfism with TSH-releasing hormone deficiency.
Topics: Adolescent; Adult; Aging; Child; Dwarfism, Pituitary; Feedback; Humans; Hypopituitarism; Hypothyroid | 1976 |
Actions of growth hormone, prolactin and thyroxine on serum somatomedin-like activity and growth in hypopituitary dwarf mice.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Dwarfism, Pituitary; Female; Growth; Growth | 1977 |
[Effects on HGH in the management of pituitary dwarfism].
Topics: Adolescent; Child; Dwarfism, Pituitary; Growth Hormone; Humans; Male; Thyroxine; Triiodothyronine | 1977 |
[Endocrinologic disorders in deletion of chromosome 18].
Topics: Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 18; Dwarfism, Pituitary; Female; Gro | 1992 |
Delayed growth in two German shepherd dog littermates with normal serum concentrations of growth hormone, thyroxine, and cortisol.
Topics: Adrenal Cortex; Animals; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Growth Disorders; Growth H | 1990 |
Total deficiency of growth hormone and prolactin, and partial deficiency of thyroid stimulating hormone in two Dutch families: a new variant of hereditary pituitary deficiency.
Topics: Adult; Arginine; Child; Child, Preschool; Dwarfism, Pituitary; Family; Female; Growth Hormone; Human | 1989 |
[Study on testicular tissue in animals with congenital hormone deficiency].
Topics: Animals; Congenital Hypothyroidism; Dwarfism, Pituitary; Growth Hormone; Hypothyroidism; Male; Mice; | 1989 |
Deficiency of immunoreactive somatostatin in the median eminence of Snell dwarf mice.
Topics: Animals; Body Weight; Castration; Dwarfism, Pituitary; Female; Growth Hormone; Median Eminence; Mice | 1985 |
Recovery from post-traumatic anterior pituitary insufficiency.
Topics: Adolescent; Adult; Age Factors; Arginine; Child; Dwarfism, Pituitary; Follicle Stimulating Hormone; | 1986 |
The anabolic actions of growth hormone and thyroxine on protein metabolism in Snell dwarf and normal mice.
Topics: Animals; Dwarfism, Pituitary; Female; Growth Hormone; Liver; Male; Mice; Mice, Inbred Strains; Muscl | 1988 |
Effects of hormone treatment on chromosomal radiosensitivity of somatic and germ cells of Snell's dwarf mice.
Topics: Animals; Cell Nucleus; Chromosome Aberrations; Dwarfism, Pituitary; Erythropoiesis; Growth Hormone; | 1988 |
Effects of hGRF treatment of a patient with hGRF deficiency.
Topics: Child; Craniopharyngioma; Dwarfism, Pituitary; Female; Growth Hormone-Releasing Hormone; Humans; Hyd | 1985 |
Hereditary pituitary dwarfism in mice affects skeletal and cardiac myosin isozyme transitions differently.
Topics: Aging; Animals; Animals, Newborn; Disease Models, Animal; Dwarfism, Pituitary; Electrophoresis, Poly | 1985 |
[Clinical study on determination of blood thyroid hormone levels using the protein binding test--free thyroxine index in young children].
Topics: Age Factors; Androgens; Antithyroid Agents; Child; Child, Preschool; Down Syndrome; Dwarfism, Pituit | 1971 |
The thyrotropin releasing hormone test in idiopathic pituitary dwarfism.
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Dwar | 1974 |
Immunoreactive growth hormone in endemic cretins in Ecuador.
Topics: Adolescent; Adult; Anthropometry; Congenital Hypothyroidism; Deafness; Dwarfism, Pituitary; Ecuador; | 1968 |
Effect of thyrotropin-releasing factor on serum thyroid-stimulating hormone. An approach to distinguishing hypothalamic from pituitary forms of idiopathic hypopituitary dwarfism.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Brain Diseases; Child; Diagnosis, Differential; Dwar | 1971 |
[Activities of the mitochondrial enzymes in the hypothyroid rat and genetically dwarf mice].
Topics: Animals; Dwarfism, Pituitary; Electron Transport Complex IV; Glutamate Dehydrogenase; Growth Hormone | 1971 |
Hormones and lymphoid tissues. Contact sensitivity and detection of theta-cells in pituitary dwarf mice.
Topics: Animals; Animals, Newborn; Antibody-Producing Cells; Antigens; Antilymphocyte Serum; Cattle; Dermati | 1973 |
Lymphocytes, hormones and ageing.
Topics: Aging; Animals; Biological Clocks; Dwarfism, Pituitary; Growth Hormone; Intestinal Mucosa; Lymph Nod | 1972 |
Abnormal thyroxine metabolism in hyposomatotrophic dwarfism and inhibition of responsiveness to TRH during GH therapy.
Topics: Adolescent; Child; Dwarfism, Pituitary; Female; Growth Hormone; Humans; Hypothyroidism; Male; Thyrot | 1973 |
The bioassay of growth hormone in Snell's dwarf mice: effects of thyroxine and prolactin on the dose-response curve.
Topics: Animals; Biological Assay; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Dwarfis | 1973 |
Primary hypothyroidism presenting as pituitary failure.
Topics: Adolescent; Diagnosis, Differential; Dwarfism; Dwarfism, Pituitary; Humans; Hypothyroidism; Male; Th | 1973 |
Sebum excretion in hypopituitarism.
Topics: Adolescent; Adult; Age Factors; Dwarfism, Pituitary; Female; Growth Hormone; Humans; Hydrocortisone; | 1973 |
Collaborative study of the effects of human growth hormone in growth hormone deficiency. II. Development and significance of antibodies to human growth hormone during the first year of therapy.
Topics: Animals; Antibody Formation; Cortisone; Dwarfism, Pituitary; Growth; Growth Hormone; Hemagglutinatio | 1974 |
Sulphation factor activity and growth rate during long-term treatment of patients with pituitary dwarfism with human growth hormone.
Topics: Androgens; Antibody Formation; Blood Proteins; Body Height; Body Weight; Bone Development; Cortisone | 1972 |
Treatment with human growth hormone (Li) for over eight years--effects of long-term therapy in a pituitary dwarf.
Topics: Adolescent; Adult; Child; Dwarfism, Pituitary; Fluoxymesterone; Growth; Growth Hormone; Humans; Male | 1971 |
Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints.
Topics: Adolescent; Adult; Age Factors; Androgens; Anthropometry; Birth Weight; Body Height; Child; Child, P | 1971 |
[Therapy of hypophyseal dwarfism].
Topics: Adolescent; Adult; Antibodies; Cortisone; Craniopharyngioma; Dwarfism, Pituitary; Female; Growth; Gr | 1970 |
Hormones and immunological capacity. II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone and thyroxin.
Topics: Animals; Antibody Formation; Dwarfism, Pituitary; Erythrocytes; Female; Growth Hormone; Hypopituitar | 1969 |
Effects of hormones on development and function of lymphoid tissues. Synergistic action of thyroxin and somatotropic hormone in pituitary dwarf mice.
Topics: Animals; Antibody Formation; Bone Marrow; Bone Marrow Cells; Drug Synergism; Dwarfism, Pituitary; Er | 1969 |
The response of two types of dwarf mice to growth hormone, thyrotropin, and thyroxine.
Topics: Animals; Body Weight; Dwarfism, Pituitary; Genetics; Growth Hormone; Mice; Thyrotropin; Thyroxine | 1965 |
Experiences with human growth hormone in pituitary dwarfism.
Topics: Adolescent; Adult; Child; Dwarfism, Pituitary; Female; Glucose Tolerance Test; Gonadotropins, Pituit | 1966 |