thyroxine has been researched along with Drug Overdose in 27 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "Our case demonstrates features of thyrotoxicosis and thyroid storm with coma after massive levothyroxine overdose." | 7.91 | Prolonged coma resulting from massive levothyroxine overdose and the utility of N-terminal prohormone brain natriuretic peptide (NT-proBNP). ( Graudins, A; Greene, S; Wong, A; Wong, O, 2019) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "Our case demonstrates features of thyrotoxicosis and thyroid storm with coma after massive levothyroxine overdose." | 3.91 | Prolonged coma resulting from massive levothyroxine overdose and the utility of N-terminal prohormone brain natriuretic peptide (NT-proBNP). ( Graudins, A; Greene, S; Wong, A; Wong, O, 2019) |
| "The effects of 3,5,3'-triiodothyronine (T3) levels on threshold, latency and duration of pentylenetetrazole-induced seizures were tested in rats treated with thyroxine (300 micrograms/kg." | 3.69 | T3 deficiency prolongs convulsions induced by acute pentylenetetrazole. ( Chambert, G; Pacheco-Rosado, J; Quevedo-Corona, L; Zamudio-Hernández, SR, 1997) |
| " He was essentially asymptomatic and suffered no apparent ill effects from this prolonged and markedly excessive dosage of l-thyroxine." | 2.38 | L-thyroxine overdose: a case of marked, severe, prolonged, excess ingestion and review of the literature. ( Geatti, O; Gross, MD; Shapiro, B, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 12 (44.44) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Goonoo, MS | 1 |
| Morris, R | 1 |
| Raithatha, A | 1 |
| Creagh, F | 1 |
| Li, R | 2 |
| Xu, YW | 1 |
| Xue, Y | 1 |
| Wu, XZ | 1 |
| Ergul, AB | 1 |
| Altuner Torun, Y | 1 |
| Serbetci, MC | 1 |
| Ozcan, A | 1 |
| Bas, VN | 1 |
| Aldasouqi, SA | 1 |
| Quickel, MA | 1 |
| Silevany, FF | 1 |
| Jamal, I | 1 |
| Xue, J | 1 |
| Zhang, L | 1 |
| Qin, Z | 1 |
| Wang, Y | 1 |
| Zhu, K | 1 |
| Li, X | 1 |
| Gao, X | 1 |
| Zhang, J | 1 |
| Wong, O | 1 |
| Wong, A | 1 |
| Greene, S | 1 |
| Graudins, A | 1 |
| Hays, HL | 1 |
| Jolliff, HA | 1 |
| Casavant, MJ | 1 |
| Allen, KM | 1 |
| Crawford, VB | 1 |
| Conaglen, JV | 1 |
| Elston, MS | 1 |
| Rothberger, GD | 1 |
| Desai, AK | 1 |
| Sharif, S | 1 |
| Chawla, SA | 1 |
| Shirazian, S | 1 |
| Bateman, DN | 1 |
| Page, CB | 1 |
| Sułek, M | 1 |
| Groszek, B | 1 |
| Zheng, F | 1 |
| Guo, G | 1 |
| Wang, BL | 1 |
| Liang, DC | 1 |
| Zhang, R | 1 |
| Zhang, JY | 1 |
| Zhao, XQ | 1 |
| Chen, ZP | 1 |
| Majlesi, N | 1 |
| Greller, HA | 1 |
| McGuigan, MA | 1 |
| Caraccio, T | 1 |
| Su, MK | 1 |
| Chan, GM | 1 |
| Georges, A | 1 |
| Charrié, A | 1 |
| Raynaud, S | 1 |
| Lombard, C | 1 |
| Corcuff, JB | 1 |
| Narula, HS | 1 |
| Kaur, S | 1 |
| Bhalla, M | 1 |
| Thami, GP | 1 |
| Naumann, UK | 1 |
| Käser, L | 1 |
| Vetter, W | 1 |
| Lo, DK | 1 |
| Szeto, CC | 1 |
| Chan, TY | 1 |
| Shapiro, B | 1 |
| Gross, MD | 1 |
| Geatti, O | 1 |
| Allain, TJ | 1 |
| Thomas, MR | 1 |
| McGregor, AM | 1 |
| Salisbury, JR | 1 |
| Matthews, SJ | 1 |
| Henderson, A | 1 |
| Hickman, P | 1 |
| Ward, G | 1 |
| Pond, SM | 1 |
| Pacheco-Rosado, J | 1 |
| Quevedo-Corona, L | 1 |
| Zamudio-Hernández, SR | 1 |
| Chambert, G | 1 |
| Shilo, L | 1 |
| Kovatz, S | 1 |
| Hadari, R | 1 |
| Weiss, E | 1 |
| Nabriski, D | 1 |
| Shenkman, L | 1 |
| Hansen, SR | 1 |
| Timmons, SP | 1 |
| Dorman, DC | 1 |
| Singh, GK | 1 |
| Winterborn, MH | 1 |
| Flood, JG | 1 |
| Williams, TD | 1 |
| Bacon, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thyroxine and Drug Overdose
| Article | Year |
|---|---|
Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes.
Topics: Antidotes; Coumarins; Disease Management; Drug Overdose; Humans; Isoniazid; Methotrexate; Thyroxine | 2016 |
L-thyroxine overdose: a case of marked, severe, prolonged, excess ingestion and review of the literature.
Topics: Adult; Dose-Response Relationship, Drug; Drug Overdose; Humans; Male; Thyroid Neoplasms; Thyroidecto | 1993 |
Acute thyroxine overdosage: two cases of parasuicide.
Topics: Adolescent; Adult; Drug Monitoring; Drug Overdose; Electrocardiography; Female; Humans; Ipecac; Pois | 1993 |
24 other studies available for thyroxine and Drug Overdose
| Article | Year |
|---|---|
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Plasmapheresis in the treatment of multi-drug intoxication involving levothyroxine sodium and calcium channel blockers: a case report.
Topics: Adult; Calcium Channel Blockers; Drug Overdose; Female; Humans; Pharmaceutical Preparations; Plasmap | 2021 |
Clinical Toxicity of Acute Overdoses With L-Thyroxin in Children.
Topics: Drug Overdose; Female; Hospitalization; Humans; Hypertension; Male; Tachycardia; Thyroid Hormones; T | 2019 |
LETTER TO THE EDITOR.
Topics: Animals; Dog Diseases; Dogs; Drug Overdose; Drug Storage; Human-Animal Bond; Humans; Patient Educati | 2018 |
No obvious sympathetic excitation after massive levothyroxine overdose: A case report.
Topics: Adrenergic beta-Antagonists; Adult; Drug Overdose; Female; Humans; Propranolol; Renal Dialysis; Symp | 2018 |
Prolonged coma resulting from massive levothyroxine overdose and the utility of N-terminal prohormone brain natriuretic peptide (NT-proBNP).
Topics: Aged; Biomarkers; Coma; Delirium; Drug Overdose; Female; Humans; Natriuretic Peptide, Brain; Peptide | 2019 |
Thyrotoxicosis after a massive levothyroxine ingestion in a 3-year-old patient.
Topics: Antiemetics; Child, Preschool; Combined Modality Therapy; Dehydration; Drug Overdose; Emergencies; E | 2013 |
Case report: clues to the diagnosis of an unsuspected massive levothyroxine overdose.
Topics: Drug Overdose; Female; Humans; Hypothyroidism; Middle Aged; Thyrotoxicosis; Thyroxine | 2015 |
The Case | Elevated lactate and osmolar gap after levothyroxine overdose.
Topics: Acidosis; Adult; Calcium Oxalate; Delirium; Drug Overdose; Ethylene Glycol; Female; Humans; Lactic A | 2015 |
[Acute poisoning with levothyroxine in own experience].
Topics: Acute Disease; Adult; Drug Interactions; Drug Overdose; Female; Humans; Male; Thyroxine; Young Adult | 2015 |
[Overdose of iodine on expression of CCK gene in rat brains].
Topics: Animals; Brain; Cholecystokinin; Drug Overdose; Female; Food, Formulated; Gene Expression; Hyperphag | 2008 |
Thyroid storm after pediatric levothyroxine ingestion.
Topics: Adrenergic beta-Antagonists; Child, Preschool; Drug Overdose; Female; Humans; Propranolol; Thyrotoxi | 2010 |
Thyroxin overdose due to rheumatoid factor interferences in thyroid-stimulating hormone assays.
Topics: Artifacts; Drug Overdose; Humans; Immunoassay; Male; Middle Aged; Rheumatoid Factor; Thyrotropin; Th | 2011 |
Accidental thyrotoxicosis caused by inadvertent ingestion of levothyroxine "dog-tabs" by a veterinarian with hypothyroidism.
Topics: Adult; Drug Overdose; Female; Humans; Thyrotoxicosis; Thyroxine; Veterinary Drugs | 2012 |
Subacute lichenoid eruption due to L-thyroxine overdosage.
Topics: Child; Drug Eruptions; Drug Overdose; Female; Humans; Hypothyroidism; Lichenoid Eruptions; Thyroxine | 2003 |
[Hypercalcemia].
Topics: Anti-Inflammatory Agents; Calcium; Carcinoma, Papillary; Diagnosis, Differential; Dihydrotachysterol | 2003 |
Mild symptoms of toxicity following deliberate ingestion of thyroxine.
Topics: Adult; Diagnosis, Differential; Drug Overdose; Female; Heart Rate; Humans; Suicide, Attempted; Thyro | 2004 |
A histomorphometric study of bone changes in thyroid dysfunction in rats.
Topics: Analysis of Variance; Animals; Body Weight; Calcinosis; Disease Models, Animal; Drug Overdose; Hyper | 1995 |
Lack of efficacy of plasmapheresis in a patient overdosed with thyroxine.
Topics: Adolescent; Charcoal; Drug Overdose; Female; Fluid Therapy; Humans; Plasma; Plasmapheresis; Serum Al | 1994 |
T3 deficiency prolongs convulsions induced by acute pentylenetetrazole.
Topics: Animals; Antithyroid Agents; Colon; Convulsants; Drug Overdose; Male; Methimazole; Pentylenetetrazol | 1997 |
Massive thyroid hormone overdose: kinetics, clinical manifestations and management.
Topics: Adolescent; Charcoal; Drug Overdose; Half-Life; Humans; Male; Metabolic Clearance Rate; Thyroxine; T | 2002 |
Acute overdose of levothyroxine in a dog.
Topics: Animals; Blood Cell Count; Charcoal; Dog Diseases; Dogs; Drug Overdose; Follow-Up Studies; Magnesium | 1992 |
Massive overdose with thyroxine,--toxicity and treatment.
Topics: Child, Preschool; Drug Overdose; Female; Humans; Thyroxine | 1991 |
Full recovery following massive overdose with insulin and thyroxine.
Topics: Drug Overdose; Drug Synergism; Humans; Insulin; Male; Middle Aged; Suicide, Attempted; Thyroxine | 1990 |