thyroxine has been researched along with Disease Models, Animal in 378 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the present study was to investigate the effect of melatonin and L-thyroxine (T4) on the expression of various receptors, and some metabolic, reproductive, and gonadotropic hormones in letrozole-induced polycystic ovary syndrome (PCOS) in rats." | 8.12 | Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome. ( Brown, GM; Cardinali, DP; Ghosh, H; Manzar, MD; Pandi-Perumal, SR; Rai, S; Reiter, RJ, 2022) |
| "Hyperthyroidism was induced in rats by daily injections of L-thyroxine (0." | 8.02 | Maternal L-thyroxine treatment during lactation affects learning and anxiety-like behaviors but not spatial memory in adult rat progeny. ( Aşçıoğlu, M; Bakkaloğlu, U; Süer, C; Tan, B, 2021) |
| " We determined the effects of venlafaxine and/or L-thyroxine on metabolic parameters and markers involved in the regulation of synaptic plasticity and cell damage in an animal model of coexisting depression and hypothyroidism, namely, Wistar Kyoto rats treated with propylthiouracil." | 8.02 | Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism. ( Budziszewska, B; Detka, J; Głombik, K, 2021) |
| "Considering the recognized role of thyroid hormones on the cardiovascular system during health and disease, we hypothesized that type 2 deiodinase (D2) activity, the main activation pathway of thyroxine (T4)-to-triiodothyronine (T3), could be an important site to modulate thyroid hormone status, which would then constitute a possible target for β-adrenergic blocking agents in a myocardial infarction (MI) model induced by left coronary occlusion in rats." | 7.91 | Propranolol inhibits myocardial infarction-induced brown adipose tissue D2 activation and maintains a low thyroid hormone state in rats. ( Araujo, IG; Império, GE; Marassi, MP; Mecawi, AS; Olivares, EL; Reis, LC; Seara, FAC; Silva, ACM, 2019) |
| "The timing of thyroxine (T4) replacement treatment in congenital hypothyroidism (CH) has been suggested to be important for optimizing cognitive recovery in humans; however this has not been fully established using modern animal models of CH." | 7.81 | Effects of thyroxine treatment on histology and behavior using the methimazole model of congenital hypothyroidism in the rat. ( Kim, EM; O'Hare, E; Page, D; Reid, R, 2015) |
| "The major purpose of this study was to investigate the effect of resveratrol (RES) on the spatial learning and memory ability in subclinical hypothyroidism (SCH) rat model and the potential mechanism." | 7.81 | Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. ( Chen, FH; Chu, CH; Ge, JF; Li, N; Qin, G; Qiu, GL; Wang, CY; Xu, YY; Zhang, Y, 2015) |
| "We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease." | 7.79 | An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 7.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "Slc26a4 (-/-) and (+/+) mice were fed up to 6 months on a standard or low iodine diet and were evaluated for thyroid structural abnormalities or biochemical hypothyroidism." | 7.77 | Absence of primary hypothyroidism and goiter in Slc26a4 (-/-) mice fed on a low iodine diet. ( Bonomi, M; Bottà, G; Calebiro, D; De Nittis, D; Fugazzola, L; Grindati, A; Lisi, S; Marinò, M; Persani, L; Porazzi, P, 2011) |
| " Therefore, the present study examined the effects of the anti-thyroid agent methimazole (MTZ) either on the panic-like behaviors induced by electrical stimulation of DPAG or the anxiety-like behaviors of rats exposed to the elevated plus-maze (EPM)." | 7.76 | Methimazole-induced hypothyroidism inhibits the panic-like behaviors produced by electrical stimulation of dorsal periaqueductal gray matter of rats. ( Rossoni, RR; Schenberg, LC; Siqueira, CC; Tiengo, AN; Tufik, S, 2010) |
| "The aim of this study was to histologically evaluate and compare the effects of the systemic administration of L-thyroxine (TX) and doxycycline (DX) on orthodontically induced root resorption, Twenty-eight male 50- to 60-day-old Wistar rats were used." | 7.76 | Comparisons of the effects of systemic administration of L-thyroxine and doxycycline on orthodontically induced root resorption in rats. ( Baysal, A; Gunhan, O; Kurt, B; Kurt, G; Ozdamar, S; Uysal, T, 2010) |
| "Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some cardiac hypertrophy models." | 7.76 | Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. ( Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL, 2010) |
| "Methimazole exerts a protective role on lungs during hepatic ischemia-reperfusion injury, which can be attributed to its anti-inflammatory and anti-oxidant effects rather than hypothyroidism alone." | 7.74 | Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism. ( Bilgihan, A; Demirci, C; Gözalan, U; Kama, NA; Tütüncü, T; Yüksek, YN, 2007) |
| "The aim of the present study was to test the hypothesis that inhibition of adenosine deaminase (ADA) enhances the efficiency of signal-transduction of myocardial A1 adenosine receptors in hyperthyroidism." | 7.74 | Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium. ( Berta, A; Gesztelyi, R; Grenczer, M; Jakab, A; Karsai, D; Kemeny-Beke, A; Pasztor, F; Szentmiklosi, AJ; Vecsernyes, M; Zsuga, J, 2007) |
| " The efficacy of coumarin (1,2-benzopyrone) was examined for the regulation of hyperthyroidism in female rats." | 7.74 | Amelioration of L-thyroxine-induced hyperthyroidism by coumarin (1,2-benzopyrone) in female rats. ( Kar, A; Panda, S, 2007) |
| "This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats." | 7.74 | Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008) |
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 7.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| "Results from previous studies indicate that hyperthyroidism increases the risk of ozone-induced lung toxicity." | 7.71 | Influence of hyperthyroidism on rat lung cytokine production and nuclear factor-kappaB activation following ozone exposure. ( Brumbaugh, K; Ding, M; Huffman, LJ; Prugh, DJ, 2002) |
| " Serum T4 and T3 concentrations of mice were found to rise immediately before the onset of muscle necrosis in the mdx mouse, and induction of hypothyroidism by treatment of animals with propylthiouracil was found to delay the onset of muscle necrosis." | 7.70 | Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice. ( Beckett, GJ; Catapano, M; Davis, A; Helliwell, TR; Jackson, MJ; McArdle, A, 1998) |
| " Four groups of rat dams, namely control, Group I, II and III were treated with propylthiouracil (PTU) in water for different length of time during pregnancy and nursing periods." | 7.70 | Effect of propylthiouracil induced hypothyroidism in developing rat cerebellum: comparison of cerebellar parameters in five day old normal and treated rat pups. ( Mwangi, DK, 1998) |
| "Levothyroxine-induced heart hypertrophy is a suitable model for severe ischemia and arrhythmias in rats." | 7.69 | Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats. ( An, LF; Dai, DZ; Guo, XF; Yu, F, 1997) |
| "Hypothyroidism was induced in rats by treatment with propylthiouracil through the mother's milk throughout the suckling period followed by surgical thyroidectomy without use of radioiodine." | 7.67 | An appropriate model for congenital hypothyroidism in the rat induced by neonatal treatment with propylthiouracil and surgical thyroidectomy: studies on learning ability and biochemical parameters. ( Kawada, J; Mino, H; Nishida, M; Yoshimura, Y, 1988) |
| " Furthermore, brain kynurenic acid levels and KATs activities were evaluated in experimental model of hypothyroidism, induced by chronic administration of 0." | 5.56 | Experimental hypothyroidism raises brain kynurenic acid - Novel aspect of thyroid dysfunction. ( Tomczyk, T; Urbańska, EM, 2020) |
| "Hydrogen sulfide (H2S) is an essential neuromodulator, generates by cystathionine β synthase (CBS) or 3-mecaptopyruvate sulfurtransferase (3MST) in the brain." | 5.48 | Cystathionine beta synthase-hydrogen sulfide system in paraventricular nucleus reduced high fatty diet induced obesity and insulin resistance by brain-adipose axis. ( Cai, J; Cui, C; Cui, Q; Geng, B; Han, J; Lu, H; Tang, C; Xu, G; Yang, J; Zheng, F; Zhou, Y, 2018) |
| "Hypothyroidism has a variety of adverse effects on cognitive function." | 5.39 | Levothyroxine replacement therapy with vitamin E supplementation prevents oxidative stress and cognitive deficit in experimental hypothyroidism. ( Pan, T; Zhang, Y; Zhong, M; Zhong, X; Zhu, D, 2013) |
| "These data indicate that the cardiac hypertrophy induced by acute treatment with thyroid hormone precedes the angiogenic process, which probably occurs later." | 5.33 | Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density. ( Anjos-Ramos, L; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Martins-Silva, J, 2006) |
| "Hyperthyroidism was associated with a 20% increase in adenosine kinase, 30% decrease in membrane 5'-nucleotidase and 15% decrease in adenosine deaminase activities measured in heart homogenates." | 5.29 | Hyperthyroidism increases adenosine transport and metabolism in the rat heart. ( Seymour, AM; Smolenski, RT; Yacoub, MH, 1995) |
| "The objective of the present study was to investigate the effect of melatonin and L-thyroxine (T4) on the expression of various receptors, and some metabolic, reproductive, and gonadotropic hormones in letrozole-induced polycystic ovary syndrome (PCOS) in rats." | 4.12 | Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome. ( Brown, GM; Cardinali, DP; Ghosh, H; Manzar, MD; Pandi-Perumal, SR; Rai, S; Reiter, RJ, 2022) |
| "Hyperthyroidism was induced in rats by daily injections of L-thyroxine (0." | 4.02 | Maternal L-thyroxine treatment during lactation affects learning and anxiety-like behaviors but not spatial memory in adult rat progeny. ( Aşçıoğlu, M; Bakkaloğlu, U; Süer, C; Tan, B, 2021) |
| "Hypothyroidism is a common pathological condition characterized by insufficient activity of the thyroid hormones (THs), thyroxine (T4), and 3,5,3'-triiodothyronine (T3), in the whole body or in specific tissues." | 4.02 | Thyroid Hormones Regulate Goblet Cell Differentiation and Fgf19-Fgfr4 Signaling. ( Appelbaum, L; Blitz, E; Guenther, S; Kubota, Y; Lerer-Goldshtein, T; Matsuda, H; Morikawa, T; Stainier, DYR; Zada, D, 2021) |
| " We determined the effects of venlafaxine and/or L-thyroxine on metabolic parameters and markers involved in the regulation of synaptic plasticity and cell damage in an animal model of coexisting depression and hypothyroidism, namely, Wistar Kyoto rats treated with propylthiouracil." | 4.02 | Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism. ( Budziszewska, B; Detka, J; Głombik, K, 2021) |
| "Considering the recognized role of thyroid hormones on the cardiovascular system during health and disease, we hypothesized that type 2 deiodinase (D2) activity, the main activation pathway of thyroxine (T4)-to-triiodothyronine (T3), could be an important site to modulate thyroid hormone status, which would then constitute a possible target for β-adrenergic blocking agents in a myocardial infarction (MI) model induced by left coronary occlusion in rats." | 3.91 | Propranolol inhibits myocardial infarction-induced brown adipose tissue D2 activation and maintains a low thyroid hormone state in rats. ( Araujo, IG; Império, GE; Marassi, MP; Mecawi, AS; Olivares, EL; Reis, LC; Seara, FAC; Silva, ACM, 2019) |
| "The novel peptides markedly reduced thyroid size, serum thyroxine levels, retro-orbital fibrosis, and tachycardia in Ad-TSHR289-immunized mice." | 3.91 | Therapeutic Effects of Short Cyclic and Combined Epitope Peptides in a Long-Term Model of Graves' Disease and Orbitopathy. ( Faßbender, J; Holthoff, HP; Li, Z; Ungerer, M, 2019) |
| "reproductive hormone profiles were analyzed by radioimmunoassay (RIA)." | 3.88 | Effects of Thyroid Dysfunction on Reproductive Hormones in Female Rats. ( Ding, Y; Guo, M; Heng, D; Hu, X; Liu, J; Liu, W; Tian, Y; Weng, X; Xu, K; Yang, Y; Zhang, C, 2018) |
| " Here we used mouse models of maternal hypo- and hyperthyroidism to investigate the long-term effects of altering thyroxine (T4) levels during pregnancy (corresponding to embryonic days 6." | 3.85 | Opposing Effects of Maternal Hypo- and Hyperthyroidism on the Stability of Thalamocortical Synapses in the Visual Cortex of Adult Offspring. ( Coleman, JE; Freeman, D; Patel, J; Poulsen, R; Rivkees, SA; Strobl, MJ; Wendler, CC, 2017) |
| "Heterozygous mutations in the thyroid hormone receptor alpha (THRA) gene cause resistance to thyroid hormone alpha (RTHα), a disease characterized by variable manifestations reminiscent of untreated congenital hypothyroidism but a raised triiodothyronine/thyroxine ratio and normal thyrotropin levels." | 3.85 | In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish. ( Carra, S; Cotelli, F; Marelli, F; Persani, L; Rurale, G, 2017) |
| " Hypothyroidism was generated in SCID-beige mice using an iodine-deficient diet containing 0." | 3.83 | Hypothyroidism Impairs Human Stem Cell-Derived Pancreatic Progenitor Cell Maturation in Mice. ( Arora, P; Bruin, JE; Fox, JK; Kieffer, TJ; Mojibian, M; O'Dwyer, S; Rezania, A; Saber, N, 2016) |
| " Hypothyroidism and hyperthyroidism were, respectively, induced in rats via administration of propylthiouracil (PTU) and L-thyroxine sodium salt in drinking water for 45 days." | 3.83 | The Effect of Experimental Thyroid Dysfunction on Markers of Oxidative Stress in Rat Pancreas. ( Hashemi, M; Nakhaee, A; Sajadian, M; Salimi, S, 2016) |
| "The timing of thyroxine (T4) replacement treatment in congenital hypothyroidism (CH) has been suggested to be important for optimizing cognitive recovery in humans; however this has not been fully established using modern animal models of CH." | 3.81 | Effects of thyroxine treatment on histology and behavior using the methimazole model of congenital hypothyroidism in the rat. ( Kim, EM; O'Hare, E; Page, D; Reid, R, 2015) |
| " In two independent experiments oral propylthiouracil (PTU) was used to induce hypothyroidism (n=9), thyroxine to induce hyperthyroidism (n=11) and mice given plain water served as control (n=8)." | 3.81 | Low thyroid hormone levels improve survival in murine model for ocular melanoma. ( Ashur-Fabian, O; Cohen, K; Davis, PJ; Ellis, M; Fabian, I; Fabian, ID; Hercbergs, A; Lin, HY; Rosner, M; Shinderman Maman, E; Vishnevskia-Dai, V; Zloto, O, 2015) |
| "The major purpose of this study was to investigate the effect of resveratrol (RES) on the spatial learning and memory ability in subclinical hypothyroidism (SCH) rat model and the potential mechanism." | 3.81 | Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. ( Chen, FH; Chu, CH; Ge, JF; Li, N; Qin, G; Qiu, GL; Wang, CY; Xu, YY; Zhang, Y, 2015) |
| " Body weight change, liver type I 5'-deiodinase (5'-DI) activity, serum total thyroxine (tT4), triiodothyroxine (tT3), thyroid stimulating hormones (TSH), and thyroid histopathological changes were measured and analyzed." | 3.81 | Thyroid disrupting effects of polychlorinated biphenyls in ovariectomized rats: A benchmark dose analysis. ( Chen, H; Jia, X; Li, Q; Liu, Z; Su, Q; Wang, W; Zhang, X, 2015) |
| "The mouse model of bronchial asthma with Yin deficiency syndrome was established by the treatment with injecting ovalbumin (OVA) two times to sensitize, inhaling OVA 14 times to stimulate, and using thyroxin through lavage during late stimulation." | 3.81 | Establishment and evaluation of a mouse model of bronchial asthma with Yin deficiency syndrome. ( Cheng, XL; Li, RK; Liu, XF; Ren, Y; Tuo, HY; Wang, ZW, 2015) |
| "Rats were rendered hypo- and hyperthyroid by daily addition of methimazole and l-thyroxine into their drinking water, respectively." | 3.80 | Effects of hypo- and hyperthyroid states on herpes simplex virus infectivity in the rat. ( Amirghofran, Z; Feizi, H; Karamizadeh, Z; Moattari, A; Varedi, M, 2014) |
| "We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease." | 3.79 | An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 3.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "To analyze the influence of hyperthyroidism on the gene expression and serum concentration of leptin, resistin, and adiponectin in obese animals." | 3.78 | Experimental hyperthyroidism decreases gene expression and serum levels of adipokines in obesity. ( Cicogna, AC; Conde, SJ; de Síbio, MT; do Nascimento, AF; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, Rde A; Nogueira, CR; Olímpio, RM, 2012) |
| " In normal female rats, the sera total thyroxine (TT4) and total triiodothyronine (TT3) levels were detectably increased at day 10 post-partum than those at day 10 of pregnancy." | 3.78 | Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system. ( Abd El-Tawab, SM; Ahmed, OM; Ahmed, RG; El-Bakry, AM; El-Gareib, AW, 2012) |
| "Slc26a4 (-/-) and (+/+) mice were fed up to 6 months on a standard or low iodine diet and were evaluated for thyroid structural abnormalities or biochemical hypothyroidism." | 3.77 | Absence of primary hypothyroidism and goiter in Slc26a4 (-/-) mice fed on a low iodine diet. ( Bonomi, M; Bottà, G; Calebiro, D; De Nittis, D; Fugazzola, L; Grindati, A; Lisi, S; Marinò, M; Persani, L; Porazzi, P, 2011) |
| " Pax8(-/-) mice are incapable of synthesizing thyroxine and serve as a model for congenital hypothyroidism." | 3.76 | Developmental changes of cone opsin expression but not retinal morphology in the hypothyroid Pax8 knockout mouse. ( Glaschke, A; Glösmann, M; Peichl, L, 2010) |
| " Therefore, the present study examined the effects of the anti-thyroid agent methimazole (MTZ) either on the panic-like behaviors induced by electrical stimulation of DPAG or the anxiety-like behaviors of rats exposed to the elevated plus-maze (EPM)." | 3.76 | Methimazole-induced hypothyroidism inhibits the panic-like behaviors produced by electrical stimulation of dorsal periaqueductal gray matter of rats. ( Rossoni, RR; Schenberg, LC; Siqueira, CC; Tiengo, AN; Tufik, S, 2010) |
| "The aim of this study was to histologically evaluate and compare the effects of the systemic administration of L-thyroxine (TX) and doxycycline (DX) on orthodontically induced root resorption, Twenty-eight male 50- to 60-day-old Wistar rats were used." | 3.76 | Comparisons of the effects of systemic administration of L-thyroxine and doxycycline on orthodontically induced root resorption in rats. ( Baysal, A; Gunhan, O; Kurt, B; Kurt, G; Ozdamar, S; Uysal, T, 2010) |
| "Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some cardiac hypertrophy models." | 3.76 | Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. ( Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL, 2010) |
| "02% methimazole (MMI) (w/v) in drinking water, while the experimental hyperthyroidism group is performed by exogenous T4 [from 50 to 200microg/kg body weight intragastric administration beside adding 0." | 3.76 | Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats. ( Ahmed, RG; El-Bakry, AM; El-Gareib, AW, 2010) |
| " Daily injection of 25 microg/100 gm body weight L-thyroxine (T4, Sigma-Aldrich) for 14 days was performed in 14 rats to induce hyperthyroidism." | 3.75 | An experimental approach to the interrelationship between hyperthyroidism and ejaculation latency time in male rats. ( Aslan, G; Cihan, A; Demir, O; Demir, T; Esen, AA; Gidener, S; Murat, N, 2009) |
| "Hyperthyroidism was induced on Wistar-Kyoto male rats with L-Thyroxine, (THYR) treatment for two weeks, N." | 3.75 | Thyroid hormone modulates the responsiveness of rat aorta to alpha1-adrenergic stimulation: an effect due to increased activation of beta2-adrenergic signaling. ( Cokkinos, DV; Karageorgiou, H; Kostopanagiotou, G; Mourouzis, I; Mourouzis, K; Pantos, C; Pappas, M; Tesseromatis, C, 2009) |
| " We hypothesized that CPU86017, derived from berberine, which possesses multi-channel blocking activity, could suppress inflammatory factors, resulting in inhibition of over-expression of ether-a-go-go (ERG) and an augmented incidence of ventricular fibrillation (VF) in ischaemia/reperfusion (I/R)." | 3.74 | Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent. ( Dai, DZ; Dai, Y; Du, RH; Tang, WH; Yi, HW, 2008) |
| "Apoptosis, proliferation and histomorphometry of spleen were investigated in ovariectomized and non-ovariectomized adult Wistar rats maintained in hypothyroidism induced by daily administration of propylthiouracil (PTU) during 120 days." | 3.74 | [Apoptosis, proliferation and spleen histomorphometry of adult female rats with thyroid and ovarian hypofunction]. ( Gomes, MG; Moro, L; Ocarino, NM; Ribeiro, AF; Serakides, R; Silva, CM; Vasconcelos, AC, 2008) |
| " Imidapril and valsartan may exert beneficial effects on hyperthyroid myocardial hypertrophy via altering intracellular calcium handling." | 3.74 | [Renin-angiotensin system blocking agents reverse the myocardial hypertrophy in experimental hyperthyroid cardiomyopathy via altering intracellular calcium handling]. ( Dai, Y; Deng, W; Su, L; Yin, YH, 2008) |
| "Methimazole exerts a protective role on lungs during hepatic ischemia-reperfusion injury, which can be attributed to its anti-inflammatory and anti-oxidant effects rather than hypothyroidism alone." | 3.74 | Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism. ( Bilgihan, A; Demirci, C; Gözalan, U; Kama, NA; Tütüncü, T; Yüksek, YN, 2007) |
| "The aim of the present study was to test the hypothesis that inhibition of adenosine deaminase (ADA) enhances the efficiency of signal-transduction of myocardial A1 adenosine receptors in hyperthyroidism." | 3.74 | Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium. ( Berta, A; Gesztelyi, R; Grenczer, M; Jakab, A; Karsai, D; Kemeny-Beke, A; Pasztor, F; Szentmiklosi, AJ; Vecsernyes, M; Zsuga, J, 2007) |
| " The efficacy of coumarin (1,2-benzopyrone) was examined for the regulation of hyperthyroidism in female rats." | 3.74 | Amelioration of L-thyroxine-induced hyperthyroidism by coumarin (1,2-benzopyrone) in female rats. ( Kar, A; Panda, S, 2007) |
| "Euthyroid (as defined by total thyroxine) senior cats with low TSH are likely to have histological evidence of nodular thyroid disease, and such cats could be considered to be subclinically hyperthyroid." | 3.74 | Subclinical hyperthyroidism in cats: a spontaneous model of subclinical toxic nodular goiter in humans? ( Elliott, J; Kirkby, R; Scase, T; Smith, K; Syme, H; Wakeling, J, 2007) |
| "This study analyzed the effects of the chronic administration of clofibrate, a peroxisome proliferator-activated receptor-alpha (PPARalpha) agonist, on the development and established hemodynamic, morphologic, metabolic, and renal manifestations of hyperthyroidism in rats." | 3.74 | Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats. ( Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F, 2008) |
| "The low plasma triiodothyronine (T3) observed during prolonged critical illness can be explained in part by suppressed hepatic deiodinase type I (D1) and increased D3 activity." | 3.74 | Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness. ( Darras, VM; Debaveye, Y; Ellger, B; Mebis, L; Van den Berghe, G, 2008) |
| " Hyperthyroidism was induced by daily injections of L-thyroxine (T4) 25 microg/100 g body weight for 14 days." | 3.73 | 5'-nucleotidase activity is altered by hypo- and hyperthyroidism in platelets from adult rats. ( Barreto-Chaves, ML; Bonan, CD; Bruno, AN; Freitas Sarkis, JJ; Pochmann, D; Ricachenevsky, FK, 2005) |
| "Methimazole (MMI), an anti-thyroid drug known to reduce serum levels of L-thyroxine (T4) and insulin-like growth factor-1 (IGF-1), has been previously reported to increase the incidence of neovascularization (NV) in an oxygen-induced retinopathy (OIR) model of retinopathy of prematurity (ROP) in rats." | 3.73 | Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. ( Fautsch, MP; Holmes, JM; Lanier, WL; Leske, DA; Mookadam, M, 2005) |
| "100mg/kg of body weight/day of l-thyroxine for 14 days, respectively) and control." | 3.73 | Tissue-specific modulation of angiotensin-converting enzyme (ACE) in hyperthyroidism. ( Barreto-Chaves, ML; Carneiro-Ramos, MS; Santos, RA; Silva, VB, 2006) |
| "Results from previous studies indicate that hyperthyroidism increases the risk of ozone-induced lung toxicity." | 3.73 | Increased susceptibility of the lungs of hyperthyroid rats to oxidant injury: specificity of effects. ( Beighley, CM; Frazer, DG; Huffman, LJ; McKinney, WG; Porter, DW, 2006) |
| "Propylthiouracil effectively causes primary hypothyroidism." | 3.72 | Effects of propylthiouracil and bromocryptine on serum concentrations of thyrotrophin and thyroid hormones in normal female horses. ( Ellersieck, MR; Ganjam, VK; Johnson, PJ; Loch, WE; Messer, NT; Refsal, KR; Thompson, DL, 2003) |
| "Chronic hypoxia in our neonatal rat model was associated with decrease in growth hormone levels and an increase in corticosterone levels." | 3.72 | Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease. ( Azar, N; Azar, ST; Bitar, FF; Dbaibo, GS; Mroueh, S; Nasser, M; Obeid, M; Zayour, D, 2003) |
| "In order to further our understanding regarding the temporal and topographic ultrastructural aspects of the myocardium under thyrotoxicosis, thyroxine (T4; 25 and 100 microg/100 g bw) was administered to young rats 24 hours after birth until 15 days." | 3.72 | Temporal and topographic ultrastructural alterations of rat heart myofibrils caused by thyroid hormone. ( Abrahamsohn, PA; Ferreira, PJ; Gouveia, CA; L'Abbate, C; Moriscot, AS, 2003) |
| " For this reason immunohistochemical investigations were carried out into the activity of the C cells in rats in an experimental model of hyperthyroidism caused by chronic thyroxine influence." | 3.72 | Preliminary immunohistochemical investigations of thyroid C cells in an experimental model of hyperthyroidism. ( Bialuk, I; Dadan, J; Puchalski, Z; Sawicki, B; Winnicka, MM; Zawadzka, A; Zbucki R, RŁ, 2003) |
| "Hyperthyroidism was induced by treating rats with L-thyroxine (12 mg/L) in the drinking water for 21 days." | 3.72 | Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo. ( Ashida, K; Inui, K; Katsura, T; Saito, H, 2004) |
| "The aim of this study was an evaluation of the activity of parafollicular (C) cells in a rat experimental model of hyperthyroidism, evoked by an intraperitoneal application of L-thyroxine (40 mg/kg daily) over 15 days." | 3.72 | Activity of thyroid parafollicular (C) cells in rats with hyperthyroidism--immunohistochemical investigations. ( Dadan, J; Puchalski, Z; Sawicki, B; Winnicka, MM; Zbucki, RL, 2004) |
| "Results from previous studies indicate that hyperthyroidism increases the risk of ozone-induced lung toxicity." | 3.71 | Influence of hyperthyroidism on rat lung cytokine production and nuclear factor-kappaB activation following ozone exposure. ( Brumbaugh, K; Ding, M; Huffman, LJ; Prugh, DJ, 2002) |
| " Serum T4 and T3 concentrations of mice were found to rise immediately before the onset of muscle necrosis in the mdx mouse, and induction of hypothyroidism by treatment of animals with propylthiouracil was found to delay the onset of muscle necrosis." | 3.70 | Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice. ( Beckett, GJ; Catapano, M; Davis, A; Helliwell, TR; Jackson, MJ; McArdle, A, 1998) |
| " Atenolol neither modified HR nor BP variability in rats with hyperthyroidism." | 3.70 | Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism. ( Elghozi, JL; Laude, D; Ponchon, P; Safa-Tisseront, V, 1998) |
| " Four groups of rat dams, namely control, Group I, II and III were treated with propylthiouracil (PTU) in water for different length of time during pregnancy and nursing periods." | 3.70 | Effect of propylthiouracil induced hypothyroidism in developing rat cerebellum: comparison of cerebellar parameters in five day old normal and treated rat pups. ( Mwangi, DK, 1998) |
| "Hyperthyroidism was induced by subcutaneous injections of L-thyroxine (T(4)) (500 mg/kg/day) for 3 days in order to study whether adrenergic and muscarinic receptor-mediated vascular responses alter at an early stage of the disease." | 3.70 | Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae. ( Honda, H; Iwata, T; Kogo, H; Mochizuki, T, 2000) |
| "Although the placenta is only a limited barrier for the transfer of thyroxine (T4) to the fetus, we have recently demonstrated that maternal T4 does not suffice to prevent the effects of in utero hypothyroidism." | 3.69 | A simple model for studying the correction of in utero hypothyroidism in the rat. ( Rigler, O; Rozin, A; Sack, J; Weller, A, 1995) |
| " There were no alterations in body weight or plasma levels of triiodotHyronine (T3) and thyroxine (T4)." | 3.69 | Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats. ( Fujita, Y; Ishihara, K; Kimura, K; Momiyama, T; Sasa, M; Serikawa, T; Todo, N, 1996) |
| "Levothyroxine-induced heart hypertrophy is a suitable model for severe ischemia and arrhythmias in rats." | 3.69 | Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats. ( An, LF; Dai, DZ; Guo, XF; Yu, F, 1997) |
| "Two experimental models of cardiac hypertrophy (chronic thyroxine or isoprenaline treatment of adult rats) were compared 24 h and five weeks after the agent was last given." | 3.68 | Functional changes in the right and left ventricle during development of cardiac hypertrophy and after its regression. ( Cihák, R; Kolár, F; Ostádal, B; Pelouch, V; Procházka, J; Widimský, J, 1992) |
| "Several studies have shown that iodine plays a role in spontaneous autoimmune thyroiditis in man and other animals." | 3.68 | Thyroidal iodine metabolism in obese-strain chickens before immune-mediated damage. ( Bagchi, N; Brown, TR; Dhar, A; Herdegen, D; Sundick, RS, 1991) |
| "Hypothyroidism was induced in rats by treatment with propylthiouracil through the mother's milk throughout the suckling period followed by surgical thyroidectomy without use of radioiodine." | 3.67 | An appropriate model for congenital hypothyroidism in the rat induced by neonatal treatment with propylthiouracil and surgical thyroidectomy: studies on learning ability and biochemical parameters. ( Kawada, J; Mino, H; Nishida, M; Yoshimura, Y, 1988) |
| "Administration of L-thyroxine (1 mg/kg) to adult rats results in cardiac hypertrophy and enhanced contractility." | 3.66 | Increased phospholipid methylation in the myocardium of hyperthyroid rats. ( Limas, CJ, 1980) |
| "The main objective of this study was to determine whether the principal abnormality of thyroid function observed in patients with chronic renal failure, low serum triiodothyronine (T(3)) concentration, causes hypothyroidism at the tissue level." | 3.66 | Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism. ( Henriquez, C; Lim, VS; Martino, E; Refetoff, S; Seo, H, 1980) |
| "In a rabbit model of prolonged critical illness, gene expression levels of MCT8 in liver and of MCT10 in skeletal muscle were increased as compared with healthy controls." | 2.74 | Expression of thyroid hormone transporters during critical illness. ( D'Hoore, A; Darras, VM; Debaveye, Y; Ellger, B; Langouche, L; Mebis, L; Paletta, D; Van den Berghe, G; Visser, TJ, 2009) |
| "Severe mental retardation of the child can occur due to compromised iodine intake or thyroid disease." | 2.43 | Thyroid hormones and fetal brain development. ( Franklyn, JA; Kilby, MD; Pemberton, HN, 2005) |
| "Papillary thyroid cancer (PTC) often co-occurs with Hashimoto's thyroiditis, an association that has long been reported in clinical studies yet remains controversial." | 1.62 | Pre-existing Thyroiditis Ameliorates Papillary Thyroid Cancer: Insights From a New Mouse Model. ( Adamo, L; Caturegli, P; Chalan, P; Di Dalmazi, G; Gabrielson, K; Mariotti, S; Pani, F; Sabini, E; Yasuda, Y, 2021) |
| "Alzheimer's disease may cause lung inflammation and treatment with low dose of T4 improved MDA level and lung inflammation." | 1.56 | Effects of levothyroxine on lung inflammation, oxidative stress and pathology in a rat model of Alzheimer's disease. ( Bavarsad, K; Boskabady, MH; Hadjzadeh, MA; Mohammadian Roshan, N; Saadat, S, 2020) |
| " Furthermore, brain kynurenic acid levels and KATs activities were evaluated in experimental model of hypothyroidism, induced by chronic administration of 0." | 1.56 | Experimental hypothyroidism raises brain kynurenic acid - Novel aspect of thyroid dysfunction. ( Tomczyk, T; Urbańska, EM, 2020) |
| "In vitro, in the LNCaP prostate cancer cell line, we found that both T3 and T4 increased the number of viable cells (Trypan blue assay), and only T4 response was fully blocked in the presence of an integrin-binding inhibitor peptide (RGD, arginine-glycine-aspartate)." | 1.56 | A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. ( Aceves, C; Álvarez, L; Anguiano, B; Delgado-González, E; Montes de Oca, C; Ortiz, Z; Rodríguez-Castelán, J; Sánchez-Tusie, A; Zarco, C, 2020) |
| "An animal model of the Alzheimer's disease (AD) was established by intracerebroventricular injection of STZ (3 mg/kg) in male Wistar rats (250 ± 50 g)." | 1.56 | Effects of levothyroxine on learning and memory deficits in a rat model of Alzheimer's disease: the role of BDNF and oxidative stress. ( Ashaari, Z; Bafadam, S; Bavarsad, K; Beheshti, F; Hadjzadeh, MA; Hosseini, M; Pakdel, R, 2020) |
| "The two autoimmune diseases are not only linked by a concordance of clinical presentations and an autoimmune/oxidative stress-mediated toxicity pathogenesis but also by an apparent biochemical commonality." | 1.51 | Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis. ( Bellanti, JA; Calderone, R; Li, D; Liang, G, 2019) |
| "However, treatment of hypothyroidism and hyperthyroidism corrected cardiac irisin levels (Fig." | 1.48 | Both experimental hypothyroidism and hyperthyroidism increase cardiac irisin levels in rats. ( Atici, E; Baltaci, AK; Menevse, E; Mogulkoc, R, 2018) |
| "Hydrogen sulfide (H2S) is an essential neuromodulator, generates by cystathionine β synthase (CBS) or 3-mecaptopyruvate sulfurtransferase (3MST) in the brain." | 1.48 | Cystathionine beta synthase-hydrogen sulfide system in paraventricular nucleus reduced high fatty diet induced obesity and insulin resistance by brain-adipose axis. ( Cai, J; Cui, C; Cui, Q; Geng, B; Han, J; Lu, H; Tang, C; Xu, G; Yang, J; Zheng, F; Zhou, Y, 2018) |
| "Whether D3 induction occurs in dilated cardiomyopathy is unknown." | 1.46 | Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy. ( Dorfman, DM; Huang, SA; Jay, PY; Jugo, RH; Maynard, MA; Padera, RF; Wassner, AJ; Zavacki, AM, 2017) |
| "Graves' disease is the most common form of autoimmune thyroid disorder, characterized by hyperthyroidism due to circulating autoantibodies." | 1.46 | Simultaneous induction of Graves' hyperthyroidism and Graves' ophthalmopathy by TSHR genetic immunization in BALB/c mice. ( Hu, X; Niu, M; Song, S; Wang, H; Wang, J; Xia, N; Xu, H; Ye, X, 2017) |
| "Cerebral ischemia was induced by middle cerebral artery occlusion in male Wistar rats." | 1.46 | Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke. ( Akbari, M; Hassanzadeh, G; Kashani, IR; Mortezaee, K; Sabbaghziarani, F; Soleimani, M; Zendedel, A, 2017) |
| "In both, thyroid cancer is driven by overactivation of PI3K-AKT signaling." | 1.43 | SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model. ( Cheng, SY; Kim, DW; Willingham, MC; Zhao, L; Zhu, X, 2016) |
| "Genetic murine models of craniosynostosis exist, but often imperfectly model human patients." | 1.43 | Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis. ( Bennfors, G; Black, L; Cray, JJ; Durham, EL; Elsalanty, M; Howie, RN; Parsons, TE; Weinberg, SM; Yu, JC, 2016) |
| " oral levothyroxine (T4) administration to induce chronic hyperthyroidism in male and female mice and asked which T4 dosing intervals are required to achieve stable organ thyrotoxicosis." | 1.43 | Efficacy of protocols for induction of chronic hyperthyroidism in male and female mice. ( Brix, K; Engels, K; Führer, D; Hönes, GS; Köhrle, J; Möller, LC; Rakov, H; Rehders, M; Zwanziger, D, 2016) |
| "Sepsis was a systemic response to a local infection." | 1.43 | Sepsis leads to thyroid impairment and dysfunction in rat model. ( Lin, X; Shi, S, 2016) |
| "A transient model for human Graves' disease was successfully established in mice using up to 3 immunizations with recombinant adenovirus expressing the extracellular A-subunit of the human TSH receptor (TSHR) (Ad-TSHR)." | 1.42 | Prolonged TSH receptor A subunit immunization of female mice leads to a long-term model of Graves' disease, tachycardia, and cardiac hypertrophy. ( Faßbender, J; Goebel, S; Holthoff, HP; Li, Z; Lohse, MJ; Münch, G; Reimann, A; Ungerer, M; Zeibig, S, 2015) |
| "Myocardial infarction leads to a reduction in nitric oxide (NO) bioavailability and an increase in reactive oxygen species (ROS) levels." | 1.42 | T3 and T4 decrease ROS levels and increase endothelial nitric oxide synthase expression in the myocardium of infarcted rats. ( Belló-Klein, A; Campos, C; Conzatti, A; da Rosa Araujo, AS; de Castro, AL; Fernandes, RO; Fernandes, TR; Llesuy, S; Sartório, CL; Schenkel, PC; Siqueira, R; Tavares, AV, 2015) |
| "Chronic levothyroxin treatment reversed hypothyroidism-induced L-LTP impairment." | 1.40 | Levothyroxin replacement therapy restores hypothyroidism induced impairment of L-LTP induction: critical role of CREB. ( Alkadhi, KA; Alzoubi, KH, 2014) |
| "Ischaemic injury was induced for 2h by middle cerebral artery occlusion (MCAo) followed by 24-h reperfusion." | 1.39 | Post-ischaemic thyroid hormone treatment in a rat model of acute stroke. ( Ahmad, A; Campolo, M; Cornelius, C; Cuzzocrea, S; Esposito, E; Genovese, T; Impellizzeri, D, 2013) |
| " After establishing hypothyroidism, rats were assigned to 1 of 5 graded T(3) dosages plus PTU for a 2-week dose-response experiment." | 1.39 | Restoration of cardiac tissue thyroid hormone status in experimental hypothyroidism: a dose-response study in female rats. ( Chen, YF; Colligiani, D; Gerdes, AM; Ojamaa, K; Pol, CJ; Saba, A; Savinova, OV; Schlenker, EH; Weltman, NY; Zucchi, R, 2013) |
| "Hypothyroidism has a variety of adverse effects on cognitive function." | 1.39 | Levothyroxine replacement therapy with vitamin E supplementation prevents oxidative stress and cognitive deficit in experimental hypothyroidism. ( Pan, T; Zhang, Y; Zhong, M; Zhong, X; Zhu, D, 2013) |
| "Treatment with ivabradine significantly reduced HR and LVESD, improved SRcirc, S long and SRlong in the T4 group, and the average I Ca,L density at 0 mV in T4-Iva groups (9." | 1.39 | Heart rate reduction with ivabradine prevents thyroid hormone-induced cardiac remodeling in rat. ( Cho, KI; Han, J; Kim, BH; Kim, IJ; Kim, JY; Kim, N; Kim, SM, 2013) |
| "A key feature of Parkinson's disease is the dopaminergic neuronal cell loss in the substantia nigra pars compacta." | 1.39 | Role of L-thyroxin in counteracting rotenone induced neurotoxicity in rats. ( El-Gamal, A; El-Gamal, M; Ellaithy, A; Helmy, B; Mohamed, M; Reda, A; Salama, M; Sheashaa, H; Sobh, M; Tantawy, D, 2013) |
| "Retinal neovascularization was quantitated at P18." | 1.38 | Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac). ( Duh, EJ; Gong, J; Wei, Y; Xu, Z; Yoshida, T, 2012) |
| "Both starvation and critical illness are hallmarked by changes in circulating thyroid hormone parameters with typically low T(3) concentrations in the absence of elevated TSH." | 1.38 | Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study. ( Darras, VM; Derde, S; Eerdekens, A; Güiza, F; Langouche, L; Mebis, L; Princen, L; Van den Berghe, G; Vanhorebeek, I; Vanwijngaerden, YM, 2012) |
| "Hypo-and hyperthyroidism were induced in rats by adding 0." | 1.38 | Effects of adult dysthyroidism on the morphology of hippocampal granular cells in rats. ( Balada, F; Garau, A; Martí-Carbonell, MA; Sala-Roca, J, 2012) |
| "Graves' disease is a B cell-mediated and T cell-dependent autoimmune disease of the thyroid which is characterized by overproduction of thyroid hormones and thyroid enlargement by agonistic anti-thyrotrophin receptor (TSHR) autoantibody." | 1.37 | B cell-targeted therapy with anti-CD20 monoclonal antibody in a mouse model of Graves' hyperthyroidism. ( Abiru, N; Eguchi, K; Ichikawa, T; Kobayashi, M; Nagayama, Y; Nakahara, M; Ueki, I, 2011) |
| "TSH elevation in primary hypothyroidism requires both the loss of feedback inhibition by thyroid hormone in the thyrotrophs and the positive effects of TRH." | 1.37 | Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase. ( Harney, JW; Larsen, PR; Lechan, RM; Marsili, A; Sanchez, E; Singru, P; Zavacki, AM, 2011) |
| "Granulomatous experimental autoimmune thyroiditis (G-EAT) is induced by mouse thyroglobulin (MTg)-sensitized splenocytes activated with MTg and interleukin (IL)-12." | 1.36 | Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice. ( Braley-Mullen, H; Chen, K; Fang, Y; Jackson, DA; Sharp, GC, 2010) |
| "The ventricular remodeling of mice were induced by subcutaneous injection of ISO with the dosage of 2 mg/kg daily for 7 d and the rats with L-Thy intraperitoneally with the dosage of 0." | 1.36 | [Effect of Chrysanthemum indicum on ventricular remodeling in rats]. ( Chen, CX; Gao, JP; Gu, WL; Lv, J; Wan, Y; Wu, Q, 2010) |
| " Recent studies, indicating that even small changes in the mother's thyroid hormone status early in pregnancy may cause adverse effects on her child, have lead to increased concern for thyroid hormone disrupting chemicals in the environment." | 1.35 | Developmental neurotoxicity of propylthiouracil (PTU) in rats: relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes. ( Axelstad, M; Boberg, J; Bonnichsen, M; Hansen, PR; Hass, U; Hougaard, KS; Lund, SP; Nellemann, C, 2008) |
| "Autoimmune thyroiditis is associated with reduced fertility and higher incidence of fetal loss." | 1.35 | Increased fetal abortion rate in autoimmune thyroid disease is related to circulating TPO autoantibodies in an autoimmune thyroiditis animal model. ( Kung, AW; Lau, KS; Lee, YL; Liu, WM; Ng, HP; O, WS; Yeung, WS, 2009) |
| "Hyperthyroidism was induced by T(4) administration (12 mg/l in drinking water for 28 days)." | 1.35 | The role of redox signaling in cardiac hypertrophy induced by experimental hyperthyroidism. ( Araujo, AS; Belló-Klein, A; Enzveiler, AT; Fernandes, TR; Khaper, N; Llesuy, S; Partata, WA; Ribeiro, MF; Schenkel, P; Singal, PK, 2008) |
| "This experimental autoimmune thyroiditis (EAT) model has been extensively characterized during early disease phases (up to d 35 after immunization)." | 1.35 | Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24. ( Caturegli, P; Chen, CY; Hagedorn, J; Kimura, H; Kimura, M; Landek-Salgado, MA; Rose, NR; Suzuki, K; Westra, W, 2009) |
| "To prevent heterotopic ossification, levothyroxin (20 microg/kg) was administered orally daily for 4 weeks to two groups of adult rabbits: group A (preload)--starting 1 week preceding bone marrow injection; group B--started on day of injection; and group C--control group (no levothyroxin) in a rabbit model." | 1.35 | Levothyroxin inhibits heterotopic ossification: an experimental study in rabbits. ( Mozaffarian, K; Namazi, H, 2008) |
| "Patients with hypothyroidism are at a higher risk for coronary vascular disease." | 1.35 | Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function. ( Gerdes, AM; Liu, Y; Redetzke, RA; Sherer, BA; Wang, D, 2009) |
| "Triiodothyronine (T3) was applied in the range of 10(-9)-10(-6) mol/l in acute experiments using isolated perfused aged (14-month-old) guinea pig hearts." | 1.35 | Thyroid hormones modulate occurrence and termination of ventricular fibrillation by both long-term and acute actions. ( Knezl, V; Okruhlicová, L; Slezák, J; Soukup, T; Tribulová, N, 2008) |
| "(2) Treatment with ezetimibe abolishes the increases in serum and liver cholesterol." | 1.35 | Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone. ( Angelin, B; Bonde, Y; Gälman, C; Matasconi, M; Rudling, M, 2008) |
| " On day 0, female Balb/c mice were infected with CB3; on day 1 of the infection, they were dosed orally with approximately 200 microg/kgbody weight (bw) (ca." | 1.33 | Common viral infection affects pentabrominated diphenyl ether (PBDE) distribution and metabolic and hormonal activities in mice. ( Bergman, A; Darnerud, PO; Ilbäck, NG; Wong, J, 2005) |
| "These data indicate that the cardiac hypertrophy induced by acute treatment with thyroid hormone precedes the angiogenic process, which probably occurs later." | 1.33 | Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density. ( Anjos-Ramos, L; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Martins-Silva, J, 2006) |
| "These findings suggest that, although autoimmune thyroiditis is an organ-specific autoimmune disease, systemic cytokine mRNA expression is also changed." | 1.33 | Hormonal change and cytokine mRNA expression in peripheral blood mononuclear cells during the development of canine autoimmune thyroiditis. ( Bae, BK; Bhang, DH; Choi, EW; Hwang, CY; Kang, MS; Kim, DY; Lee, CW; Lee, DH; Shin, IS; Youn, HY, 2006) |
| " Montmorillonite at dosage of 1." | 1.33 | Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect. ( Cai, Y; Cao, YX; Lu, H; Meng, XF; Zhou, LZ; Zhu, SF, 2006) |
| "Hypothyroidism was created by adding mercasolil (10 mg/kg) to the standard diet." | 1.33 | [Effect of hypothyroidism on glial fibrillary acid protein in the structures of the rat brain]. ( Demchenko, OM; Nerush, PO, 2006) |
| "Prenatal hypothyroidism has an adverse effect on bone growth and results in reduction of long bone length." | 1.32 | Effect of hypothyroidism and thyroxin replacement on growth of long bones in prenatally treated albino rats. ( Ahmed, M; Janjua, Z, 2003) |
| "The etiology of Graves' disease is multifactorial." | 1.32 | A major role for non-major histocompatibility complex genes but not for microorganisms in a novel murine model of Graves' hyperthyroidism. ( McLachlan, SM; Nagayama, Y; Niwa, M; Rapoport, B, 2003) |
| "An experimental murine model of Graves' disease was used to produce monoclonal antibodies (mAbs) with thyroid stimulating activity." | 1.32 | Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. ( Bonomi, M; Costagliola, S; Morgenthaler, NG; Panneels, V; Refetoff, S; Van Durme, J; Vassart, G, 2004) |
| "Imipramine (IMI) treatment normalized tT4 values." | 1.31 | Effects of chronic mild stress (CMS) on thyroid hormone function in two rat strains. ( Antoniou, K; Bekris, S; Christofidis, I; Kioukia, N; Papadopoulou-Daifoti, Z, 2000) |
| "Thyrotoxicosis was produced by a daily intraperitoneal (i." | 1.31 | [Contribution of the renin-angiotensin system to blood pressure variability in hyperthyroid rats]. ( Basset, A; Blanc, J; Elghozi, JL, 2000) |
| "Nitrofen treatment led to decreased plasma T3 and T4 levels without TSH changes." | 1.30 | Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen. ( Alfonso, LF; Alvarez, FJ; Arnaiz, A; Diez-Pardo, JA; Morreale de Escobar, G; Qi, B; Tovar, JA; Valls-i-Soler, A, 1997) |
| "Hyperthyroidism was associated with a 20% increase in adenosine kinase, 30% decrease in membrane 5'-nucleotidase and 15% decrease in adenosine deaminase activities measured in heart homogenates." | 1.29 | Hyperthyroidism increases adenosine transport and metabolism in the rat heart. ( Seymour, AM; Smolenski, RT; Yacoub, MH, 1995) |
| " L-T4 treatment resulted in reduction in BMDs in the lumbar spine, tail, and femur as measured by dual energy X-ray absorptiometry, but there was no correlation with the dosage of L-T4 or the serum T4 level." | 1.29 | A rat model of thyroid hormone-induced bone loss: effect of antiresorptive agents on regional bone density and osteocalcin gene expression. ( Kung, AW; Ng, F, 1994) |
| "Brain death was caused in young pigs (25-38 kg) by rapid inflation of an intracranially implanted balloon catheter." | 1.29 | The influence of thyroid hormone replacement in a porcine brain death model. ( Bird, S; Hickman, R; Innes, CR; Lotz, Z; Schwartz, I, 1993) |
| "Central hypothyroidism is an uncommon condition characterized by insufficient thyroid gland stimulation by TSH, owing to hypothalamic and/or pituitary dysfunction." | 1.28 | Central hypothyroidism. ( Ridgway, EC; Samuels, MH, 1992) |
| " Group I dosage was based on the reported T4 production rate in dogs and is slightly greater than the reported production rate in man." | 1.27 | Thyroid replacement in thyroparathyroidectomized dogs. ( Bonner, EL; Gustafson, LE; Hulter, HN; Mackie, S; Toto, RD, 1984) |
| "Inhabitants of many severe endemic goiter areas have low serum T4 and high circulating TSH, despite normal levels of T3." | 1.26 | Are iodine-deficient rats euthyroid? ( De Escobar, GM; Del Rey, FE; Lamas, L; Obregon, MJ; Rodriguez-Peña, A; Santisteban, P, 1982) |
| "The incidence of lymphocytic thyroiditis was strikingly increased in 8-10-mo-old diabetic rats (59%) as compared with their nondiabetic cohorts (11%) (P less than 0." | 1.26 | Lymphocytic thyroiditis and diabetes in the BB/W rat. A new model of autoimmune endocrinopathy. ( Braverman, LE; Like, AA; Sarantis, K; Sternthal, E, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (17.20) | 18.7374 |
| 1990's | 57 (15.08) | 18.2507 |
| 2000's | 106 (28.04) | 29.6817 |
| 2010's | 128 (33.86) | 24.3611 |
| 2020's | 22 (5.82) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 2 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Ghosh, H | 1 |
| Rai, S | 1 |
| Manzar, MD | 1 |
| Pandi-Perumal, SR | 1 |
| Brown, GM | 1 |
| Reiter, RJ | 1 |
| Cardinali, DP | 1 |
| Venediktova, N | 1 |
| Solomadin, I | 1 |
| Nikiforova, A | 1 |
| Starinets, V | 1 |
| Mironova, G | 1 |
| Lossow, K | 1 |
| Renko, K | 2 |
| Schwarz, M | 1 |
| Schomburg, L | 1 |
| Schwerdtle, T | 1 |
| Kipp, AP | 1 |
| Li, D | 3 |
| Li, Y | 3 |
| Chen, Y | 2 |
| Li, H | 2 |
| She, Y | 1 |
| Zhang, X | 2 |
| Chen, S | 1 |
| Chen, W | 1 |
| Qiu, G | 1 |
| Huang, H | 1 |
| Zhang, S | 1 |
| Groeneweg, S | 1 |
| Kersseboom, S | 1 |
| van den Berge, A | 1 |
| Dolcetta-Capuzzo, A | 1 |
| van Geest, FS | 1 |
| van Heerebeek, REA | 1 |
| Arjona, FJ | 1 |
| Meima, ME | 1 |
| Peeters, RP | 1 |
| Visser, WE | 1 |
| Visser, TJ | 4 |
| Seara, FAC | 1 |
| Araujo, IG | 2 |
| Império, GE | 1 |
| Marassi, MP | 2 |
| Silva, ACM | 1 |
| Mecawi, AS | 2 |
| Reis, LC | 2 |
| Olivares, EL | 2 |
| Wang, Y | 3 |
| Zhu, S | 1 |
| Liu, H | 1 |
| Wei, W | 1 |
| Tu, Y | 2 |
| Chen, C | 1 |
| Song, J | 1 |
| Li, J | 3 |
| Sun, S | 1 |
| Wang, C | 1 |
| Xu, Z | 2 |
| Haselman, JT | 1 |
| Olker, JH | 1 |
| Kosian, PA | 1 |
| Korte, JJ | 1 |
| Swintek, JA | 1 |
| Denny, JS | 1 |
| Nichols, JW | 1 |
| Tietge, JE | 1 |
| Hornung, MW | 1 |
| Degitz, SJ | 1 |
| Bavarsad, K | 2 |
| Saadat, S | 1 |
| Mohammadian Roshan, N | 1 |
| Hadjzadeh, MA | 2 |
| Boskabady, MH | 1 |
| Venediktova, NI | 1 |
| Mashchenko, OV | 1 |
| Talanov, EY | 1 |
| Belosludtseva, NV | 1 |
| Mironova, GD | 1 |
| Owji, MS | 1 |
| Varedi, M | 2 |
| Naghibalhossaini, F | 1 |
| Pajouhi, N | 1 |
| Tomczyk, T | 1 |
| Urbańska, EM | 1 |
| Ortiz, VD | 1 |
| Türck, P | 1 |
| Teixeira, R | 1 |
| Belló-Klein, A | 4 |
| de Castro, AL | 3 |
| Araujo, ASDR | 1 |
| Sánchez-Tusie, A | 1 |
| Montes de Oca, C | 1 |
| Rodríguez-Castelán, J | 1 |
| Delgado-González, E | 1 |
| Ortiz, Z | 1 |
| Álvarez, L | 1 |
| Zarco, C | 1 |
| Aceves, C | 1 |
| Anguiano, B | 1 |
| de Souza Cardoso, J | 1 |
| Baldissarelli, J | 1 |
| Reichert, KP | 1 |
| Teixeira, FC | 1 |
| Pereira Soares, MS | 1 |
| Chitolina Schetinger, MR | 1 |
| Morsch, VM | 1 |
| Farias Martins Filho, AO | 1 |
| Duarte Junior, HR | 1 |
| Ribeiro Coriolano, FH | 1 |
| Spanevello, RM | 1 |
| Stefanello, FM | 1 |
| Tavares, RG | 1 |
| Cros-Brunsó, L | 1 |
| Camacho-Rodríguez, L | 1 |
| Martínez-González, Á | 1 |
| Llévenes, P | 1 |
| Salaices, M | 1 |
| García-Redondo, AB | 1 |
| Blanco-Rivero, J | 1 |
| Tan, B | 3 |
| Bakkaloğlu, U | 1 |
| Aşçıoğlu, M | 1 |
| Süer, C | 4 |
| Blitz, E | 1 |
| Matsuda, H | 1 |
| Guenther, S | 1 |
| Morikawa, T | 1 |
| Kubota, Y | 1 |
| Zada, D | 1 |
| Lerer-Goldshtein, T | 1 |
| Stainier, DYR | 1 |
| Appelbaum, L | 1 |
| Zhang, C | 2 |
| Qin, L | 1 |
| Sun, B | 1 |
| Wu, Y | 1 |
| Zhong, F | 1 |
| Wu, L | 3 |
| Liu, T | 2 |
| Sun, F | 1 |
| Fang, Y | 2 |
| Zhang, MM | 1 |
| Zhang, RJ | 1 |
| Wu, FY | 1 |
| Yang, RM | 1 |
| Tu, PH | 1 |
| Dong, M | 1 |
| Zhao, SX | 1 |
| Song, HD | 1 |
| Badi, R | 1 |
| Głombik, K | 1 |
| Detka, J | 1 |
| Budziszewska, B | 1 |
| Pani, F | 1 |
| Yasuda, Y | 1 |
| Di Dalmazi, G | 1 |
| Chalan, P | 1 |
| Gabrielson, K | 1 |
| Adamo, L | 1 |
| Sabini, E | 1 |
| Mariotti, S | 1 |
| Caturegli, P | 2 |
| Kerp, H | 1 |
| Hönes, GS | 2 |
| Brix, K | 2 |
| Köhrle, J | 3 |
| Moeller, LC | 1 |
| Führer, D | 2 |
| Wassner, AJ | 1 |
| Jugo, RH | 1 |
| Dorfman, DM | 1 |
| Padera, RF | 1 |
| Maynard, MA | 1 |
| Zavacki, AM | 2 |
| Jay, PY | 1 |
| Huang, SA | 1 |
| Xia, N | 1 |
| Ye, X | 1 |
| Hu, X | 3 |
| Song, S | 1 |
| Xu, H | 1 |
| Niu, M | 1 |
| Wang, H | 2 |
| Wang, J | 1 |
| Donangelo, I | 1 |
| Abe, K | 1 |
| Scremin, O | 1 |
| Ke, S | 1 |
| Li, F | 2 |
| Milanesi, A | 1 |
| Liu, YY | 1 |
| Brent, GA | 1 |
| Simon, MJK | 2 |
| Beil, FT | 3 |
| Pogoda, P | 3 |
| Vettorazzi, E | 2 |
| Clarke, I | 1 |
| Amling, M | 3 |
| Oheim, R | 3 |
| Bellelli, R | 1 |
| Vitagliano, D | 1 |
| Federico, G | 1 |
| Marotta, P | 1 |
| Tamburrino, A | 1 |
| Salerno, P | 1 |
| Paciello, O | 1 |
| Papparella, S | 1 |
| Knauf, JA | 1 |
| Fagin, JA | 1 |
| Refetoff, S | 8 |
| Troncone, G | 1 |
| Santoro, M | 1 |
| Shabani, S | 2 |
| Farbood, Y | 2 |
| Mard, SA | 1 |
| Sarkaki, A | 2 |
| Ahangarpour, A | 2 |
| Khorsandi, L | 2 |
| Atici, E | 1 |
| Menevse, E | 1 |
| Baltaci, AK | 1 |
| Mogulkoc, R | 1 |
| Rajabi, M | 1 |
| Yalcin, M | 1 |
| Mousa, SA | 1 |
| Zhang, J | 2 |
| Huang, J | 1 |
| Aximujiang, K | 1 |
| Xu, C | 1 |
| Ahemaiti, A | 1 |
| Wu, G | 1 |
| Zhong, L | 1 |
| Yunusi, K | 1 |
| Zhang, K | 1 |
| Tang, YD | 1 |
| Zhang, Y | 5 |
| Ojamaa, K | 2 |
| Saini, AS | 1 |
| Carrillo-Sepulveda, MA | 1 |
| Rajagopalan, V | 1 |
| Gerdes, AM | 6 |
| Liu, J | 2 |
| Guo, M | 1 |
| Weng, X | 1 |
| Tian, Y | 1 |
| Xu, K | 1 |
| Heng, D | 1 |
| Liu, W | 1 |
| Ding, Y | 1 |
| Yang, Y | 1 |
| Hosseini, M | 1 |
| Pakdel, R | 1 |
| Beheshti, F | 1 |
| Bafadam, S | 1 |
| Ashaari, Z | 1 |
| Zheng, F | 1 |
| Han, J | 2 |
| Lu, H | 2 |
| Cui, C | 1 |
| Yang, J | 2 |
| Cui, Q | 1 |
| Cai, J | 1 |
| Zhou, Y | 1 |
| Tang, C | 1 |
| Xu, G | 1 |
| Geng, B | 1 |
| Nana, AW | 1 |
| Wu, SY | 1 |
| Yang, YS | 1 |
| Chin, YT | 1 |
| Cheng, TM | 1 |
| Ho, Y | 1 |
| Li, WS | 1 |
| Liao, YM | 1 |
| Chen, YR | 1 |
| Shih, YJ | 1 |
| Liu, YR | 1 |
| Pedersen, J | 1 |
| Incerpi, S | 1 |
| Hercbergs, A | 2 |
| Liu, LF | 1 |
| Whang-Peng, J | 1 |
| Davis, PJ | 2 |
| Lin, HY | 2 |
| Faßbender, J | 2 |
| Holthoff, HP | 2 |
| Li, Z | 2 |
| Ungerer, M | 2 |
| Proshin, S | 1 |
| Bagaturiya, G | 1 |
| Karpova, I | 1 |
| Kurbanov, R | 1 |
| Glushakov, R | 1 |
| Malagola, E | 1 |
| Chen, R | 1 |
| Bombardo, M | 1 |
| Saponara, E | 1 |
| Dentice, M | 1 |
| Salvatore, D | 1 |
| Reding, T | 1 |
| Myers, S | 1 |
| Hills, AP | 1 |
| Graf, R | 1 |
| Sonda, S | 1 |
| Liu, Z | 2 |
| Chen, G | 1 |
| Mao, X | 1 |
| Wei, X | 1 |
| Li, X | 1 |
| Xu, Y | 1 |
| Jiang, F | 1 |
| Wang, K | 1 |
| Liu, C | 1 |
| Lin, JD | 1 |
| Fang, WF | 1 |
| Tang, KT | 1 |
| Cheng, CW | 1 |
| Liang, G | 1 |
| Calderone, R | 1 |
| Bellanti, JA | 1 |
| Genovese, T | 1 |
| Impellizzeri, D | 1 |
| Ahmad, A | 1 |
| Cornelius, C | 1 |
| Campolo, M | 1 |
| Cuzzocrea, S | 1 |
| Esposito, E | 1 |
| Weltman, NY | 1 |
| Savinova, OV | 1 |
| Chen, YF | 1 |
| Schlenker, EH | 1 |
| Zucchi, R | 1 |
| Saba, A | 1 |
| Colligiani, D | 1 |
| Pol, CJ | 1 |
| Kang, P | 1 |
| Yao, Y | 1 |
| Shen, B | 1 |
| Zhou, Z | 1 |
| Pei, F | 1 |
| Hung, PL | 1 |
| Huang, CC | 1 |
| Huang, HM | 1 |
| Tu, DG | 1 |
| Chang, YC | 1 |
| Bindl, R | 1 |
| Gruchenberg, K | 1 |
| Reitmaier, S | 1 |
| Wehner, T | 1 |
| Calcia, E | 1 |
| Radermacher, P | 1 |
| Claes, L | 1 |
| Ignatius, A | 2 |
| Moattari, A | 1 |
| Amirghofran, Z | 1 |
| Karamizadeh, Z | 1 |
| Feizi, H | 1 |
| Wang, XF | 1 |
| Zhang, L | 3 |
| Ma, N | 1 |
| Luo, LC | 1 |
| Wu, QH | 1 |
| Wu, LP | 1 |
| Fu, J | 1 |
| Lv, HJ | 1 |
| Guan, XY | 1 |
| Xu, L | 3 |
| Chen, P | 1 |
| Gao, CQ | 1 |
| Hou, P | 3 |
| Ji, MJ | 1 |
| Shi, BY | 1 |
| Sawano, E | 1 |
| Takahashi, M | 1 |
| Negishi, T | 1 |
| Tashiro, T | 1 |
| Vose, LR | 1 |
| Vinukonda, G | 1 |
| Jo, S | 1 |
| Miry, O | 1 |
| Diamond, D | 1 |
| Korumilli, R | 1 |
| Arshad, A | 1 |
| Zia, MT | 1 |
| Hu, F | 1 |
| Kayton, RJ | 1 |
| La Gamma, EF | 1 |
| Bansal, R | 1 |
| Bianco, AC | 1 |
| Ballabh, P | 1 |
| Alzoubi, KH | 1 |
| Alkadhi, KA | 1 |
| Schang, AL | 1 |
| Van Steenwinckel, J | 1 |
| Chevenne, D | 1 |
| Alkmark, M | 1 |
| Hagberg, H | 1 |
| Gressens, P | 1 |
| Fleiss, B | 1 |
| Bagnato, G | 2 |
| Bitto, A | 1 |
| Irrera, N | 1 |
| Pizzino, G | 1 |
| Sangari, D | 1 |
| Cinquegrani, M | 1 |
| Roberts, W | 1 |
| Atteritano, M | 1 |
| Altavilla, D | 1 |
| Squadrito, F | 1 |
| Saitta, A | 1 |
| Buras, A | 1 |
| Battle, L | 1 |
| Landers, E | 1 |
| Nguyen, T | 1 |
| Vasudevan, N | 1 |
| Dong, H | 1 |
| You, SH | 1 |
| Williams, A | 1 |
| Wade, MG | 1 |
| Yauk, CL | 1 |
| Thomas Zoeller, R | 1 |
| Zumrutdal, E | 1 |
| Karateke, F | 1 |
| Daglioglu, K | 1 |
| Gulkaya, M | 1 |
| Colak, O | 1 |
| Koksal, F | 1 |
| Yang, SS | 1 |
| Tang, L | 1 |
| Li, RG | 1 |
| Ge, GH | 1 |
| Qu, XK | 1 |
| Ma, JW | 1 |
| Qiao, ZY | 1 |
| Liu, HJ | 1 |
| Hou, YM | 1 |
| Cao, H | 1 |
| Hao, ZM | 1 |
| Cheng, WB | 1 |
| Wang, HW | 1 |
| Szkudlarek, AC | 1 |
| Aldenucci, B | 1 |
| Miyagui, NI | 1 |
| Silva, IK | 1 |
| Moraes, RN | 1 |
| Ramos, HE | 1 |
| Fogaça, RT | 1 |
| Willems, E | 1 |
| Hu, TT | 1 |
| Soler Vasco, L | 1 |
| Buyse, J | 1 |
| Decuypere, E | 1 |
| Arckens, L | 1 |
| Everaert, N | 1 |
| Tavares, AV | 2 |
| Campos, C | 2 |
| Fernandes, RO | 2 |
| Siqueira, R | 2 |
| Conzatti, A | 2 |
| Bicca, AM | 1 |
| Fernandes, TR | 3 |
| Sartório, CL | 2 |
| Schenkel, PC | 2 |
| da Rosa Araujo, AS | 2 |
| Yi, J | 1 |
| Zheng, JY | 1 |
| Zhang, W | 1 |
| Wang, S | 2 |
| Yang, ZF | 1 |
| Dou, KF | 1 |
| Castelo-Branco, G | 1 |
| Stridh, P | 1 |
| Guerreiro-Cacais, AO | 1 |
| Adzemovic, MZ | 1 |
| Falcão, AM | 1 |
| Marta, M | 1 |
| Berglund, R | 1 |
| Gillett, A | 1 |
| Hamza, KH | 1 |
| Lassmann, H | 1 |
| Hermanson, O | 1 |
| Jagodic, M | 1 |
| Dedkov, EI | 1 |
| Lee, B | 1 |
| Pun, K | 1 |
| O'Hare, E | 2 |
| Kim, EM | 2 |
| Page, D | 2 |
| Reid, R | 1 |
| Bozhkov, AI | 1 |
| Nikitchenko, YV | 1 |
| Goebel, S | 1 |
| Reimann, A | 1 |
| Zeibig, S | 1 |
| Lohse, MJ | 1 |
| Münch, G | 1 |
| Mori, Y | 1 |
| Tomonaga, D | 1 |
| Kalashnikova, A | 1 |
| Furuya, F | 1 |
| Akimoto, N | 1 |
| Ifuku, M | 1 |
| Okuno, Y | 1 |
| Beppu, K | 1 |
| Fujita, K | 1 |
| Katafuchi, T | 1 |
| Shimura, H | 1 |
| Churilov, LP | 1 |
| Noda, M | 1 |
| Guo, Y | 1 |
| Wan, SY | 1 |
| Zhong, X | 2 |
| Zhong, MK | 1 |
| Pan, TR | 1 |
| Fabian, ID | 1 |
| Rosner, M | 1 |
| Fabian, I | 1 |
| Vishnevskia-Dai, V | 1 |
| Zloto, O | 1 |
| Shinderman Maman, E | 1 |
| Cohen, K | 1 |
| Ellis, M | 1 |
| Ashur-Fabian, O | 1 |
| Gao, C | 1 |
| Li, T | 1 |
| Guo, Q | 1 |
| Tian, L | 1 |
| Llesuy, S | 2 |
| Ge, JF | 1 |
| Xu, YY | 1 |
| Li, N | 2 |
| Qiu, GL | 1 |
| Chu, CH | 1 |
| Wang, CY | 1 |
| Qin, G | 1 |
| Chen, FH | 1 |
| Uysal, E | 1 |
| Kirdak, T | 1 |
| Korun, N | 1 |
| Korner, G | 1 |
| Noain, D | 1 |
| Ying, M | 1 |
| Hole, M | 1 |
| Flydal, MI | 1 |
| Scherer, T | 1 |
| Allegri, G | 1 |
| Rassi, A | 1 |
| Fingerhut, R | 1 |
| Becu-Villalobos, D | 1 |
| Pillai, S | 1 |
| Wueest, S | 1 |
| Konrad, D | 1 |
| Lauber-Biason, A | 1 |
| Baumann, CR | 1 |
| Bindoff, LA | 1 |
| Martinez, A | 1 |
| Thöny, B | 1 |
| Lino, CA | 1 |
| da Silva, IB | 1 |
| Shibata, CE | 1 |
| Monteiro, Pde S | 1 |
| Barreto-Chaves, ML | 5 |
| Chen, H | 1 |
| Jia, X | 1 |
| Li, Q | 1 |
| Su, Q | 1 |
| Wang, W | 1 |
| Murphy, T | 1 |
| Huang, B | 1 |
| Veitla, V | 1 |
| Scherlag, BJ | 1 |
| Kem, DC | 1 |
| Yu, X | 2 |
| Li, QM | 1 |
| Wei, JP | 1 |
| Li, M | 1 |
| Meng, SH | 1 |
| Gilbert, ME | 1 |
| Sanchez-Huerta, K | 1 |
| Wood, C | 1 |
| Nijampurkar, B | 1 |
| Qureshi, F | 1 |
| Jain, N | 1 |
| Banerjee, T | 1 |
| Kumar, A | 1 |
| Parmar, HS | 1 |
| Bruin, JE | 1 |
| Saber, N | 1 |
| O'Dwyer, S | 1 |
| Fox, JK | 1 |
| Mojibian, M | 1 |
| Arora, P | 1 |
| Rezania, A | 1 |
| Kieffer, TJ | 1 |
| Ding, L | 1 |
| Wu, W | 1 |
| Saad, NS | 1 |
| Floyd, K | 1 |
| Ahmed, AA | 1 |
| Mohler, PJ | 1 |
| Janssen, PM | 1 |
| Elnakish, MT | 1 |
| Bitiktaş, S | 3 |
| Kavraal, Ş | 2 |
| Dursun, N | 2 |
| Dönmez Altuntaş, H | 1 |
| Wang, ZW | 1 |
| Li, RK | 1 |
| Ren, Y | 1 |
| Liu, XF | 1 |
| Cheng, XL | 1 |
| Tuo, HY | 1 |
| Wang, R | 2 |
| Shan, Z | 2 |
| Dong, Y | 1 |
| Zheng, H | 1 |
| Jesse, FF | 1 |
| Rao, E | 1 |
| Takahashi, E | 1 |
| Teng, W | 2 |
| Teng, X | 1 |
| Strobl, MJ | 1 |
| Freeman, D | 1 |
| Patel, J | 1 |
| Poulsen, R | 1 |
| Wendler, CC | 1 |
| Rivkees, SA | 1 |
| Coleman, JE | 1 |
| Sajadian, M | 1 |
| Hashemi, M | 1 |
| Salimi, S | 1 |
| Nakhaee, A | 1 |
| Kandemir, B | 1 |
| Liman, N | 2 |
| Dönmez-Altuntaş, H | 1 |
| Aksan-Kurnaz, I | 1 |
| Zhu, X | 1 |
| Kim, DW | 1 |
| Zhao, L | 2 |
| Willingham, MC | 2 |
| Cheng, SY | 2 |
| Cheng, S | 1 |
| Xing, W | 1 |
| Pourteymoor, S | 1 |
| Mohan, S | 1 |
| Yousefzadeh, N | 1 |
| Jeddi, S | 1 |
| Alipour, MR | 1 |
| Durham, EL | 1 |
| Howie, RN | 1 |
| Black, L | 1 |
| Bennfors, G | 1 |
| Parsons, TE | 1 |
| Elsalanty, M | 1 |
| Yu, JC | 1 |
| Weinberg, SM | 1 |
| Cray, JJ | 1 |
| Sabatino, L | 1 |
| Kusmic, C | 1 |
| Nicolini, G | 1 |
| Amato, R | 1 |
| Casini, G | 1 |
| Iervasi, G | 2 |
| Balzan, S | 1 |
| Engels, K | 1 |
| Rakov, H | 1 |
| Zwanziger, D | 1 |
| Rehders, M | 1 |
| Möller, LC | 1 |
| Lin, X | 1 |
| Shi, S | 2 |
| Kayes, TD | 1 |
| Weisman, GA | 1 |
| Camden, JM | 1 |
| Woods, LT | 1 |
| Bredehoeft, C | 1 |
| Downey, EF | 1 |
| Cole, J | 1 |
| Braley-Mullen, H | 2 |
| Ali Mard, S | 1 |
| Marelli, F | 1 |
| Carra, S | 1 |
| Rurale, G | 1 |
| Cotelli, F | 1 |
| Persani, L | 2 |
| Lv, PP | 1 |
| Tian, S | 1 |
| Feng, C | 1 |
| Li, JY | 1 |
| Yu, DQ | 1 |
| Jin, L | 1 |
| Shen, Y | 1 |
| Yu, TT | 1 |
| Meng, Y | 1 |
| Ding, GL | 1 |
| Jin, M | 1 |
| Chen, XJ | 1 |
| Sheng, JZ | 1 |
| Zhang, D | 1 |
| Huang, HF | 1 |
| Sabbaghziarani, F | 1 |
| Mortezaee, K | 1 |
| Akbari, M | 1 |
| Kashani, IR | 1 |
| Soleimani, M | 1 |
| Hassanzadeh, G | 1 |
| Zendedel, A | 1 |
| Shu, L | 1 |
| Hoo, RL | 1 |
| Wu, X | 3 |
| Pan, Y | 1 |
| Lee, IP | 1 |
| Cheong, LY | 1 |
| Bornstein, SR | 1 |
| Rong, X | 1 |
| Guo, J | 1 |
| Xu, A | 1 |
| Steiner, M | 1 |
| Barvencik, F | 1 |
| Clarke, IJ | 1 |
| Zheng, W | 2 |
| Tan, J | 1 |
| Meng, Z | 1 |
| Maralcan, G | 1 |
| Erkol, H | 1 |
| Erkol, Z | 1 |
| Yanar, F | 1 |
| Plevin, R | 1 |
| Leite, ED | 2 |
| de Freitas, ES | 1 |
| de Almeida Souza, C | 1 |
| de Melo Ocarino, N | 1 |
| Cassali, GD | 3 |
| Serakides, R | 4 |
| Axelstad, M | 1 |
| Hansen, PR | 1 |
| Boberg, J | 1 |
| Bonnichsen, M | 1 |
| Nellemann, C | 1 |
| Lund, SP | 1 |
| Hougaard, KS | 1 |
| Hass, U | 1 |
| Rocksén, D | 1 |
| Elfsmark, D | 1 |
| Heldestad, V | 1 |
| Wallgren, K | 1 |
| Cassel, G | 1 |
| Göransson Nyberg, A | 1 |
| Du, RH | 1 |
| Yi, HW | 1 |
| Dai, DZ | 4 |
| Tang, WH | 1 |
| Dai, Y | 4 |
| Branvold, DJ | 1 |
| Allred, DR | 1 |
| Beckstead, DJ | 1 |
| Kim, HJ | 1 |
| Fillmore, N | 1 |
| Condon, BM | 1 |
| Brown, JD | 1 |
| Sudweeks, SN | 1 |
| Thomson, DM | 1 |
| Winder, WW | 1 |
| Huang, ZJ | 1 |
| Feng, Y | 1 |
| Na, T | 1 |
| Tang, XY | 1 |
| Lee, YL | 1 |
| Ng, HP | 2 |
| Lau, KS | 1 |
| Liu, WM | 1 |
| O, WS | 1 |
| Yeung, WS | 1 |
| Kung, AW | 3 |
| Jiang, JY | 1 |
| Miyabayashi, K | 1 |
| Nottola, SA | 1 |
| Umezu, M | 3 |
| Cecconi, S | 1 |
| Sato, E | 2 |
| Macchiarelli, G | 1 |
| Araujo, AS | 1 |
| Schenkel, P | 1 |
| Enzveiler, AT | 1 |
| Partata, WA | 1 |
| Ribeiro, MF | 1 |
| Khaper, N | 1 |
| Singal, PK | 1 |
| Chen, CY | 1 |
| Kimura, H | 2 |
| Landek-Salgado, MA | 1 |
| Hagedorn, J | 1 |
| Kimura, M | 1 |
| Suzuki, K | 1 |
| Westra, W | 1 |
| Rose, NR | 1 |
| Gomes, MG | 3 |
| Silva, CM | 1 |
| Ribeiro, AF | 1 |
| Ocarino, NM | 1 |
| Moro, L | 1 |
| Vasconcelos, AC | 1 |
| Namazi, H | 1 |
| Mozaffarian, K | 1 |
| Rohani, MH | 1 |
| Akbari, Z | 1 |
| Behzadi, G | 1 |
| Cihan, A | 1 |
| Murat, N | 1 |
| Demir, O | 1 |
| Aslan, G | 1 |
| Demir, T | 1 |
| Gidener, S | 1 |
| Esen, AA | 1 |
| Su, L | 1 |
| Deng, W | 1 |
| Yin, YH | 1 |
| Frick, LR | 1 |
| Rapanelli, M | 1 |
| Bussmann, UA | 1 |
| Klecha, AJ | 1 |
| Arcos, ML | 1 |
| Genaro, AM | 1 |
| Cremaschi, GA | 1 |
| Hou, LB | 1 |
| Hou, YC | 1 |
| Reda, M | 1 |
| Zickri, M | 1 |
| Liu, Y | 2 |
| Wang, D | 1 |
| Redetzke, RA | 2 |
| Sherer, BA | 1 |
| Mebis, L | 3 |
| Paletta, D | 1 |
| Debaveye, Y | 2 |
| Ellger, B | 2 |
| Langouche, L | 2 |
| D'Hoore, A | 1 |
| Darras, VM | 4 |
| Van den Berghe, G | 4 |
| Endo, T | 1 |
| Kobayashi, T | 1 |
| Berbel, P | 1 |
| Navarro, D | 1 |
| Ausó, E | 1 |
| Varea, E | 1 |
| Rodríguez, AE | 1 |
| Ballesta, JJ | 1 |
| Salinas, M | 1 |
| Flores, E | 1 |
| Faura, CC | 1 |
| de Escobar, GM | 3 |
| Glaschke, A | 1 |
| Glösmann, M | 1 |
| Peichl, L | 1 |
| Chen, K | 1 |
| Jackson, DA | 1 |
| Sharp, GC | 1 |
| Derde, S | 2 |
| Vanhorebeek, I | 2 |
| Ververs, EJ | 1 |
| Vanhees, I | 1 |
| Van Herck, E | 1 |
| Larsson, L | 1 |
| Siqueira, CC | 1 |
| Rossoni, RR | 1 |
| Tiengo, AN | 1 |
| Tufik, S | 1 |
| Schenberg, LC | 1 |
| Shukla, PK | 1 |
| Sittig, LJ | 1 |
| Andrus, BM | 1 |
| Schaffer, DJ | 1 |
| Batra, KK | 1 |
| Redei, EE | 1 |
| Randall, W | 1 |
| Liittschwager, J | 1 |
| Pappas, M | 1 |
| Mourouzis, K | 1 |
| Karageorgiou, H | 1 |
| Tesseromatis, C | 1 |
| Mourouzis, I | 3 |
| Kostopanagiotou, G | 1 |
| Pantos, C | 3 |
| Cokkinos, DV | 3 |
| Baysal, A | 1 |
| Uysal, T | 1 |
| Ozdamar, S | 1 |
| Kurt, B | 1 |
| Kurt, G | 1 |
| Gunhan, O | 1 |
| Leghait, J | 1 |
| Gayrard, V | 1 |
| Toutain, PL | 1 |
| Picard-Hagen, N | 1 |
| Viguié, C | 1 |
| Lu, C | 1 |
| Ying, H | 1 |
| Carneiro-Ramos, MS | 3 |
| Diniz, GP | 2 |
| Nadu, AP | 1 |
| Almeida, J | 1 |
| Vieira, RL | 1 |
| Santos, RA | 2 |
| Pathak, A | 1 |
| Sinha, RA | 1 |
| Mohan, V | 1 |
| Mitra, K | 1 |
| Godbole, MM | 2 |
| El-Bakry, AM | 2 |
| El-Gareib, AW | 2 |
| Ahmed, RG | 2 |
| Liu, D | 1 |
| Gao, Y | 1 |
| Fan, C | 1 |
| Zhang, H | 1 |
| Calebiro, D | 1 |
| Porazzi, P | 1 |
| Bonomi, M | 2 |
| Lisi, S | 1 |
| Grindati, A | 1 |
| De Nittis, D | 1 |
| Fugazzola, L | 1 |
| Marinò, M | 1 |
| Bottà, G | 1 |
| Malik, IA | 1 |
| Baumgartner, BG | 1 |
| Naz, N | 1 |
| Sheikh, N | 1 |
| Moriconi, F | 1 |
| Ramadori, G | 1 |
| Wu, Q | 1 |
| Chen, CX | 1 |
| Gu, WL | 1 |
| Gao, JP | 1 |
| Wan, Y | 1 |
| Lv, J | 1 |
| Ye, F | 2 |
| Shi, B | 2 |
| Gao, L | 2 |
| Ma, X | 2 |
| Ueki, I | 1 |
| Abiru, N | 1 |
| Kobayashi, M | 1 |
| Nakahara, M | 1 |
| Ichikawa, T | 1 |
| Eguchi, K | 1 |
| Nagayama, Y | 2 |
| Taşkın, E | 1 |
| Artis, AS | 1 |
| Dolu, N | 1 |
| Marsili, A | 1 |
| Sanchez, E | 1 |
| Singru, P | 1 |
| Harney, JW | 1 |
| Lechan, RM | 2 |
| Larsen, PR | 1 |
| Peng, YR | 1 |
| Qian, DW | 1 |
| Duan, JA | 1 |
| Ding, YH | 1 |
| Buckley, MM | 1 |
| Johns, EJ | 1 |
| Silva-Almeida, C | 1 |
| Pestana, FM | 1 |
| Sonoda-Côrtes, R | 1 |
| Rodrigues, NC | 1 |
| Côrtes, WS | 1 |
| Rocha, FF | 1 |
| Yoshida, T | 2 |
| Gong, J | 1 |
| Wei, Y | 1 |
| Duh, EJ | 1 |
| Mantzouratou, P | 1 |
| Galanopoulos, G | 1 |
| Kostakou, E | 1 |
| Roukounakis, N | 1 |
| Kokkinos, AD | 2 |
| Eerdekens, A | 1 |
| Güiza, F | 1 |
| Princen, L | 1 |
| Vanwijngaerden, YM | 1 |
| Grasberger, H | 1 |
| De Deken, X | 1 |
| Mayo, OB | 1 |
| Raad, H | 1 |
| Weiss, M | 1 |
| Liao, XH | 3 |
| Mensching, DA | 1 |
| Slater, M | 1 |
| Scott, JW | 1 |
| Ferguson, DC | 1 |
| Beasley, VR | 1 |
| Jena, S | 1 |
| Dandapat, J | 1 |
| Chainy, GB | 2 |
| Kapoor, R | 1 |
| Desouza, LA | 1 |
| Nanavaty, IN | 1 |
| Kernie, SG | 1 |
| Vaidya, VA | 1 |
| Luvizotto, Rde A | 1 |
| do Nascimento, AF | 1 |
| de Síbio, MT | 1 |
| Olímpio, RM | 1 |
| Conde, SJ | 1 |
| Lima-Leopoldo, AP | 1 |
| Leopoldo, AS | 1 |
| Cicogna, AC | 1 |
| Nogueira, CR | 1 |
| Ahmed, OM | 1 |
| Abd El-Tawab, SM | 1 |
| Hamidi, S | 1 |
| Aliesky, HA | 1 |
| Williams, RW | 1 |
| Rapoport, B | 3 |
| McLachlan, SM | 2 |
| Pan, T | 1 |
| Zhong, M | 1 |
| Zhu, D | 1 |
| Antonica, F | 1 |
| Kasprzyk, DF | 1 |
| Opitz, R | 1 |
| Iacovino, M | 1 |
| Dumitrescu, AM | 2 |
| Peremans, K | 1 |
| Manto, M | 1 |
| Kyba, M | 1 |
| Costagliola, S | 4 |
| Martí-Carbonell, MA | 2 |
| Garau, A | 2 |
| Sala-Roca, J | 2 |
| Balada, F | 2 |
| Kim, BH | 1 |
| Cho, KI | 1 |
| Kim, SM | 1 |
| Kim, N | 1 |
| Kim, JY | 1 |
| Kim, IJ | 1 |
| Salama, M | 1 |
| Helmy, B | 1 |
| El-Gamal, M | 1 |
| Reda, A | 1 |
| Ellaithy, A | 1 |
| Tantawy, D | 1 |
| Mohamed, M | 1 |
| El-Gamal, A | 1 |
| Sheashaa, H | 1 |
| Sobh, M | 1 |
| Minato, K | 1 |
| Tomimatsu, T | 1 |
| Mimura, K | 1 |
| Jugder, O | 1 |
| Kakigano, A | 1 |
| Kanayama, T | 1 |
| Fujita, S | 1 |
| Taniguchi, Y | 1 |
| Kanagawa, T | 1 |
| Endo, M | 1 |
| Kimura, T | 1 |
| Wendl, T | 1 |
| Lun, K | 1 |
| Mione, M | 1 |
| Favor, J | 1 |
| Brand, M | 1 |
| Wilson, SW | 1 |
| Rohr, KB | 1 |
| Huffman, LJ | 2 |
| Prugh, DJ | 1 |
| Brumbaugh, K | 1 |
| Ding, M | 1 |
| Yamada, M | 1 |
| Li, AW | 1 |
| West, KA | 1 |
| Chang, CH | 1 |
| Wall, JR | 1 |
| Friedrichsen, S | 1 |
| Christ, S | 1 |
| Heuer, H | 1 |
| Schäfer, MK | 1 |
| Mansouri, A | 1 |
| Bauer, K | 2 |
| Xu, W | 1 |
| Cao, Y | 1 |
| Ahmed, M | 1 |
| Janjua, Z | 1 |
| Deane, R | 1 |
| Redzic, Z | 1 |
| Preston, JE | 1 |
| Segal, MB | 1 |
| Niwa, M | 1 |
| Rooman, RP | 1 |
| Kuijpers, G | 1 |
| Gresnigt, R | 1 |
| Bloemen, R | 1 |
| Koster, JG | 1 |
| van Buul-Offers, SC | 1 |
| Johnson, PJ | 1 |
| Messer, NT | 1 |
| Ganjam, VK | 1 |
| Thompson, DL | 1 |
| Refsal, KR | 1 |
| Loch, WE | 1 |
| Ellersieck, MR | 1 |
| Zayour, D | 1 |
| Azar, ST | 1 |
| Azar, N | 1 |
| Nasser, M | 1 |
| Obeid, M | 1 |
| Mroueh, S | 1 |
| Dbaibo, GS | 1 |
| Bitar, FF | 1 |
| Sarkar, PK | 1 |
| Ray, AK | 1 |
| Rodríguez, E | 1 |
| García, AM | 1 |
| Foyo, E | 1 |
| Amato, D | 1 |
| Paniagua, R | 1 |
| Banga, JP | 2 |
| Ferreira, PJ | 1 |
| L'Abbate, C | 1 |
| Abrahamsohn, PA | 1 |
| Gouveia, CA | 1 |
| Moriscot, AS | 1 |
| Sechman, A | 1 |
| Rzasa, J | 1 |
| Paczoska-Eliasiewicz, H | 1 |
| Dadan, J | 3 |
| Zbucki R, RŁ | 1 |
| Sawicki, B | 2 |
| Bialuk, I | 1 |
| Zawadzka, A | 1 |
| Winnicka, MM | 3 |
| Puchalski, Z | 3 |
| Giovambattista, A | 1 |
| Suescun, MO | 1 |
| Nessralla, CC | 1 |
| França, LR | 1 |
| Spinedi, E | 1 |
| Calandra, RS | 1 |
| Yilmazer-Hanke, DM | 1 |
| Hantsch, M | 1 |
| Hanke, J | 1 |
| Schulz, C | 1 |
| Faber-Zuschratter, H | 1 |
| Schwegler, H | 1 |
| Rabeler, R | 1 |
| Mittag, J | 1 |
| Geffers, L | 1 |
| Rüther, U | 1 |
| Leitges, M | 1 |
| Parlow, AF | 1 |
| Shionoya, H | 1 |
| Sugihara, Y | 1 |
| Okano, K | 1 |
| Sagami, F | 1 |
| Mikami, T | 1 |
| Katayama, K | 1 |
| Ashida, K | 1 |
| Katsura, T | 1 |
| Saito, H | 1 |
| Inui, K | 1 |
| Chattopadhyay, S | 1 |
| Zaidi, G | 1 |
| Das, K | 1 |
| Morgenthaler, NG | 1 |
| Van Durme, J | 1 |
| Panneels, V | 1 |
| Vassart, G | 3 |
| Abdel-Galil, KA | 1 |
| Al-Hazimi, AM | 1 |
| Fernandez, M | 1 |
| Giuliani, A | 1 |
| Pirondi, S | 1 |
| D'Intino, G | 1 |
| Giardino, L | 1 |
| Aloe, L | 1 |
| Levi-Montalcini, R | 1 |
| Calzà, L | 1 |
| Ali, AA | 1 |
| Velasquez, MT | 1 |
| Hansen, CT | 1 |
| Mohamed, AI | 1 |
| Bhathena, SJ | 1 |
| Baker, G | 1 |
| Mazziotti, G | 1 |
| von Ruhland, C | 1 |
| Ludgate, M | 2 |
| Zbucki, R | 1 |
| Andrzejewska, A | 1 |
| Zbucki, RL | 1 |
| Satoh, M | 1 |
| Haruta-Satoh, E | 1 |
| Omori, A | 1 |
| Oh-Ishi, M | 1 |
| Kodera, Y | 1 |
| Furudate, S | 1 |
| Maeda, T | 1 |
| Tatsumi, K | 1 |
| Haga, S | 1 |
| Matsuyoshi, H | 1 |
| Inoue, M | 1 |
| Manabe, T | 1 |
| Makinodan, M | 1 |
| Wanaka, A | 1 |
| Bruno, AN | 1 |
| Pochmann, D | 1 |
| Ricachenevsky, FK | 1 |
| Bonan, CD | 1 |
| Freitas Sarkis, JJ | 1 |
| Darnerud, PO | 2 |
| Wong, J | 1 |
| Bergman, A | 1 |
| Ilbäck, NG | 2 |
| Iwasaki-Ishizuka, Y | 1 |
| Yamato, H | 1 |
| Nii-Kono, T | 1 |
| Kurokawa, K | 1 |
| Fukagawa, M | 1 |
| Helmreich, DL | 1 |
| Parfitt, DB | 1 |
| Lu, XY | 1 |
| Akil, H | 1 |
| Watson, SJ | 1 |
| Nerush, PO | 2 |
| Demchenko, OM | 2 |
| Pemberton, HN | 1 |
| Franklyn, JA | 1 |
| Kilby, MD | 1 |
| Liou, YM | 1 |
| Chang, LY | 1 |
| Liaw, JM | 1 |
| Jiang, MJ | 1 |
| Mookadam, M | 1 |
| Leske, DA | 1 |
| Fautsch, MP | 1 |
| Lanier, WL | 1 |
| Holmes, JM | 1 |
| Anjos-Ramos, L | 1 |
| Martins-Silva, J | 1 |
| Weiss, RE | 1 |
| Millen, K | 1 |
| Silva, VB | 1 |
| Beighley, CM | 1 |
| Frazer, DG | 1 |
| McKinney, WG | 1 |
| Porter, DW | 1 |
| Bik, W | 1 |
| Wolinska-Witort, E | 1 |
| Pawlak, J | 1 |
| Skwarlo-Sonta, K | 1 |
| Chmielowska, M | 1 |
| Martynska, L | 1 |
| Baranowska-Bik, A | 1 |
| Baranowska, B | 1 |
| Xia, HJ | 1 |
| Seetharamaiah, GS | 2 |
| Land, KJ | 1 |
| Choi, EW | 1 |
| Shin, IS | 1 |
| Bhang, DH | 1 |
| Lee, DH | 1 |
| Bae, BK | 1 |
| Kang, MS | 1 |
| Kim, DY | 1 |
| Hwang, CY | 1 |
| Lee, CW | 1 |
| Youn, HY | 1 |
| Cai, Y | 1 |
| Meng, XF | 1 |
| Cao, YX | 1 |
| Zhu, SF | 1 |
| Zhou, LZ | 1 |
| Jatwa, R | 1 |
| Kar, A | 2 |
| Ferreira, E | 2 |
| da Silva, AE | 1 |
| Douglas, N | 1 |
| Olmedo, P | 1 |
| Douglas, CR | 1 |
| Monte, O | 1 |
| Kaneda, T | 1 |
| Honda, A | 1 |
| Hakozaki, A | 1 |
| Fuse, T | 1 |
| Muto, A | 1 |
| Farahvar, A | 1 |
| Meisami, E | 1 |
| Johnson, KR | 1 |
| Marden, CC | 1 |
| Ward-Bailey, P | 1 |
| Gagnon, LH | 1 |
| Bronson, RT | 1 |
| Donahue, LR | 1 |
| Tütüncü, T | 1 |
| Demirci, C | 1 |
| Gözalan, U | 1 |
| Yüksek, YN | 1 |
| Bilgihan, A | 1 |
| Kama, NA | 1 |
| Reid, RE | 1 |
| O'Mara, SM | 1 |
| Rivas, M | 1 |
| Naranjo, JR | 1 |
| Markakis, K | 1 |
| Dimopoulos, A | 1 |
| Xinaris, C | 1 |
| Panagiotou, M | 1 |
| Kemeny-Beke, A | 1 |
| Jakab, A | 1 |
| Zsuga, J | 1 |
| Vecsernyes, M | 1 |
| Karsai, D | 1 |
| Pasztor, F | 1 |
| Grenczer, M | 1 |
| Szentmiklosi, AJ | 1 |
| Berta, A | 1 |
| Gesztelyi, R | 1 |
| Ciosek, J | 1 |
| Panda, S | 1 |
| Freitas, ES | 1 |
| Souza, Cde A | 1 |
| Ocarino, Nde M | 1 |
| Lundgren, M | 1 |
| Molin, Y | 1 |
| Lilienthal, H | 1 |
| Blomberg, J | 1 |
| Chae, HJ | 1 |
| Lee, GY | 1 |
| Yang, SK | 1 |
| Kim, DS | 1 |
| Yun, KJ | 1 |
| Kim, EC | 1 |
| Kim, HM | 1 |
| Chae, SW | 1 |
| Kim, HR | 1 |
| Wakeling, J | 1 |
| Smith, K | 1 |
| Scase, T | 1 |
| Kirkby, R | 1 |
| Elliott, J | 1 |
| Syme, H | 1 |
| Estebanez-Perpina, E | 1 |
| Rodríguez-Gómez, I | 1 |
| Cruz, A | 1 |
| Moreno, JM | 1 |
| Soler, A | 1 |
| Osuna, A | 1 |
| Vargas, F | 2 |
| Said, S | 1 |
| Pottala, JV | 1 |
| Mustafa, S | 1 |
| Al-Bader, MD | 1 |
| Elgazzar, AH | 1 |
| Alshammeri, J | 1 |
| Gopinath, S | 1 |
| Essam, H | 1 |
| Knezl, V | 1 |
| Soukup, T | 1 |
| Okruhlicová, L | 1 |
| Slezák, J | 1 |
| Tribulová, N | 1 |
| Gälman, C | 1 |
| Bonde, Y | 1 |
| Matasconi, M | 1 |
| Angelin, B | 1 |
| Rudling, M | 1 |
| Feitosa, Dda S | 1 |
| Bezerra, Bde B | 1 |
| Ambrosano, GM | 1 |
| Nociti, FH | 1 |
| Casati, MZ | 1 |
| Sallum, EA | 1 |
| de Toledo, S | 1 |
| van den Hove-Vandenbroucke, MF | 1 |
| Santisteban, P | 3 |
| Couvreur, M | 1 |
| Obregon, MJ | 4 |
| Lamas, L | 3 |
| Petkov, O | 1 |
| Lim, VS | 2 |
| Passo, C | 1 |
| Murata, Y | 1 |
| Ferrari, E | 1 |
| Nakamura, H | 1 |
| Lever, EG | 1 |
| Medeiros-Neto, GA | 1 |
| DeGroot, LJ | 1 |
| Limas, CJ | 1 |
| Harkness, JE | 1 |
| Hymer, WC | 1 |
| Rosenberger, JL | 1 |
| Grindeland, RE | 1 |
| Kuhn, CM | 1 |
| Bartolome, M | 1 |
| Scott, SM | 1 |
| Chou, PJ | 1 |
| Fisher, DA | 1 |
| Rodríguez-Peña, A | 2 |
| Pascual, A | 1 |
| Cartagena, P | 1 |
| Ruiz-Marcos, A | 1 |
| Escobar del Rey, F | 1 |
| Morreale de Escobar, G | 3 |
| Hulter, HN | 1 |
| Gustafson, LE | 1 |
| Bonner, EL | 1 |
| Toto, RD | 1 |
| Mackie, S | 1 |
| Henriquez, C | 1 |
| Seo, H | 1 |
| Martino, E | 1 |
| Del Rey, FE | 1 |
| Sternthal, E | 1 |
| Like, AA | 1 |
| Sarantis, K | 1 |
| Braverman, LE | 1 |
| Paloyan, E | 2 |
| Hofmann, C | 1 |
| Prinz, RA | 1 |
| Oslapas, R | 1 |
| Shah, KH | 1 |
| Ku, WW | 1 |
| Ernst, K | 1 |
| Smith, M | 1 |
| Lawrence, AM | 2 |
| Solleveld, HA | 1 |
| Coolen, J | 1 |
| Hollander, CF | 1 |
| Zurcher, C | 1 |
| Anand, BS | 1 |
| Mahmood, A | 1 |
| Dilawari, JB | 1 |
| Rehani, MM | 1 |
| Kulcsár, A | 1 |
| Kulcsár-Gergely, J | 1 |
| Kulcsár, L | 1 |
| Potter, BJ | 2 |
| Jones, GB | 1 |
| Buckley, RA | 1 |
| Belling, GB | 2 |
| McIntosh, GH | 1 |
| Hetzel, BS | 2 |
| Kong, YC | 1 |
| McCormick, DJ | 2 |
| Wan, Q | 2 |
| Motte, RW | 2 |
| Fuller, BE | 2 |
| Giraldo, AA | 2 |
| David, CS | 2 |
| Lomo, PO | 1 |
| Makawiti, DW | 1 |
| Konji, VN | 1 |
| Boelen, A | 1 |
| Platvoet-ter Schiphorst, MC | 1 |
| Bakker, O | 1 |
| Wiersinga, WM | 1 |
| Smolenski, RT | 1 |
| Yacoub, MH | 1 |
| Seymour, AM | 1 |
| Sack, J | 1 |
| Weller, A | 1 |
| Rigler, O | 1 |
| Rozin, A | 1 |
| Allain, TJ | 1 |
| Thomas, MR | 1 |
| McGregor, AM | 2 |
| Salisbury, JR | 1 |
| Dawe, K | 1 |
| Hutchings, P | 1 |
| Champion, B | 1 |
| Cooke, A | 1 |
| Roitt, I | 1 |
| Chattopadhyay, N | 1 |
| Kher, R | 1 |
| Virmani, J | 1 |
| Sabio, JM | 1 |
| Rodriguez-Maresca, M | 1 |
| Luna, JD | 1 |
| García del Río, C | 1 |
| Carayanniotis, G | 1 |
| Huang, GC | 1 |
| Nicholson, LB | 1 |
| Scott, T | 1 |
| Allain, P | 1 |
| Many, MC | 2 |
| Stalmans-Falys, M | 1 |
| Tonacchera, M | 1 |
| Ng, F | 1 |
| Kakucska, I | 1 |
| Romero, LI | 1 |
| Clark, BD | 1 |
| Rondeel, JM | 1 |
| Qi, Y | 1 |
| Alex, S | 1 |
| Emerson, CH | 1 |
| Kizior, MJ | 1 |
| Chai, JY | 1 |
| Turner, DW | 1 |
| Stern, PH | 1 |
| Vail, DM | 1 |
| Elfarra, AA | 1 |
| Cooley, AJ | 1 |
| Panciera, DL | 1 |
| MacEwen, EG | 1 |
| Soergel, SA | 1 |
| Yamamoto, M | 1 |
| Markatos, A | 1 |
| Seedor, JG | 1 |
| Masarachia, P | 1 |
| Gentile, M | 1 |
| Rodan, GA | 1 |
| Balena, R | 1 |
| Martin, A | 2 |
| Valentine, M | 1 |
| Unger, P | 1 |
| Lichtenstein, C | 1 |
| Schwartz, AE | 1 |
| Friedman, EW | 1 |
| Shultz, LD | 2 |
| Davies, TF | 2 |
| Schwartz, I | 1 |
| Bird, S | 1 |
| Lotz, Z | 1 |
| Innes, CR | 1 |
| Hickman, R | 1 |
| Tomanek, RJ | 1 |
| Butters, CA | 1 |
| Zimmerman, MB | 1 |
| Fujimura, T | 1 |
| Sugawara, S | 1 |
| Kagabu, S | 2 |
| O'Malley, BW | 1 |
| Turner, DS | 1 |
| Momiyama, T | 1 |
| Ishihara, K | 1 |
| Kimura, K | 1 |
| Todo, N | 1 |
| Fujita, Y | 1 |
| Serikawa, T | 1 |
| Sasa, M | 1 |
| Bányász, T | 1 |
| Vér, A | 1 |
| Kovács, T | 1 |
| Schumm-Draeger, PM | 1 |
| Fortmeyer, HP | 1 |
| Vasilatos-Younken, R | 1 |
| Dunnington, EA | 1 |
| Siegel, PB | 1 |
| McMurtry, JP | 1 |
| Kohno, K | 1 |
| Palha, JA | 1 |
| Miyakawa, K | 1 |
| Saraiva, MJ | 1 |
| Ito, S | 1 |
| Mabuchi, T | 1 |
| Blaner, WS | 1 |
| Iijima, H | 1 |
| Tsukahara, S | 1 |
| Episkopou, V | 1 |
| Gottesman, ME | 1 |
| Shimada, K | 1 |
| Takahashi, K | 1 |
| Yamamura, K | 1 |
| Maeda, S | 1 |
| Baumgartner, A | 1 |
| Eravci, M | 1 |
| Pinna, G | 1 |
| Hiedra, L | 1 |
| Prengel, H | 1 |
| Brödel, O | 1 |
| Meinhold, H | 1 |
| Paloyan Walker, R | 1 |
| Kazuko, E | 1 |
| Gopalsami, C | 1 |
| Bassali, J | 1 |
| Zeiger, MA | 1 |
| Saji, M | 1 |
| Gusev, Y | 1 |
| Westra, WH | 1 |
| Takiyama, Y | 1 |
| Dooley, WC | 1 |
| Kohn, LD | 1 |
| Levine, MA | 1 |
| Nishino, S | 1 |
| Arrigoni, J | 1 |
| Shelton, J | 1 |
| Kanbayashi, T | 1 |
| Dement, WC | 1 |
| Mignot, E | 1 |
| Tovar, JA | 1 |
| Qi, B | 1 |
| Diez-Pardo, JA | 1 |
| Alfonso, LF | 1 |
| Arnaiz, A | 1 |
| Alvarez, FJ | 1 |
| Valls-i-Soler, A | 1 |
| Kong, YM | 1 |
| Chen, MD | 2 |
| Lin, PY | 1 |
| Lin, WH | 1 |
| Islam, N | 1 |
| Chanda, S | 1 |
| Ghosh, TK | 1 |
| Mitra, C | 1 |
| McArdle, A | 1 |
| Helliwell, TR | 1 |
| Beckett, GJ | 1 |
| Catapano, M | 1 |
| Davis, A | 1 |
| Jackson, MJ | 1 |
| Overton, TR | 1 |
| Drackley, JK | 1 |
| Ottemann-Abbamonte, CJ | 1 |
| Beaulieu, AD | 1 |
| Clark, JH | 1 |
| Safa-Tisseront, V | 1 |
| Ponchon, P | 1 |
| Laude, D | 1 |
| Elghozi, JL | 2 |
| Abel, ED | 1 |
| Kaulbach, HC | 1 |
| Campos-Barros, A | 1 |
| Ahima, RS | 1 |
| Boers, ME | 1 |
| Hashimoto, K | 1 |
| Forrest, D | 1 |
| Wondisford, FE | 1 |
| Mwangi, DK | 1 |
| Yu, F | 1 |
| An, LF | 1 |
| Guo, XF | 1 |
| Jiang, J | 1 |
| Evans, IM | 1 |
| Sinha, AK | 1 |
| Pickard, MR | 1 |
| Edwards, PR | 1 |
| Leonard, AJ | 1 |
| Ekins, RP | 1 |
| Kaplanskiĭ, AS | 1 |
| Durnova, GN | 1 |
| Ili'ina-Kakueva, EI | 1 |
| Loginov, VI | 1 |
| Patibandla, SA | 1 |
| Fan, JL | 1 |
| Prabhakar, BS | 1 |
| Gupta, RP | 1 |
| Verma, PC | 1 |
| Chaturvedi, GC | 1 |
| Nathaniel, EJ | 1 |
| Hassard, T | 1 |
| Burton, L | 1 |
| Novak, C | 1 |
| Denef, JF | 1 |
| Pohlenz, J | 1 |
| Pishak, VP | 1 |
| Dolomatov, SI | 1 |
| Klykov, OV | 1 |
| Cherevko, IM | 1 |
| Kioukia, N | 1 |
| Bekris, S | 1 |
| Antoniou, K | 1 |
| Papadopoulou-Daifoti, Z | 1 |
| Christofidis, I | 1 |
| Basset, A | 1 |
| Blanc, J | 1 |
| Honda, H | 1 |
| Iwata, T | 1 |
| Mochizuki, T | 1 |
| Kogo, H | 1 |
| Gromakova, IA | 1 |
| Zilberman, ST | 1 |
| Konovalenko, OA | 1 |
| Bagriacik, EU | 1 |
| Zhou, Q | 1 |
| Wang, HC | 1 |
| Klein, JR | 1 |
| Chandrasekharan, S | 1 |
| Qiu, TH | 1 |
| Alkharouf, N | 1 |
| Brantley, K | 1 |
| Mitchell, JB | 1 |
| Liu, ET | 1 |
| Hatotani, N | 1 |
| Nomura, J | 1 |
| Yamaguchi, T | 1 |
| Kitayama, I | 1 |
| Burman, KD | 1 |
| Yeager, HC | 1 |
| Briggs, WA | 1 |
| Earll, JM | 1 |
| Wartofsky, L | 1 |
| Afflitto, JJ | 1 |
| Inchiosa, MA | 1 |
| Fuller, GC | 1 |
| Matoney, AL | 1 |
| Fisher, DO | 1 |
| Fausto, N | 1 |
| Cardinale, GJ | 1 |
| Holl, JE | 1 |
| Howard, LS | 1 |
| van Voorthuizen, WF | 1 |
| de Vijlder, JJ | 1 |
| van Dijk, JE | 1 |
| Tegelaers, WH | 1 |
| Malinow, MR | 1 |
| McLaughlin, O | 1 |
| Papworth, L | 1 |
| Naito, HK | 1 |
| Lewis, L | 1 |
| McNulty, WP | 1 |
| Clark, OH | 1 |
| Lambert, WR | 1 |
| Cavalieri, RR | 1 |
| Hammond, ME | 1 |
| Ingbar, SH | 1 |
| Zaninovich, AA | 1 |
| Brown, TJ | 1 |
| Bromage, NR | 1 |
| Matty, AJ | 1 |
| Hollingsworth, DR | 1 |
| Belin, RP | 1 |
| Parker, JC | 1 |
| Moser, RJ | 1 |
| McKean, H | 1 |
| Horger, EO | 1 |
| Kenimer, JG | 1 |
| Azukizawa, M | 1 |
| Hershman, JM | 1 |
| Kansal, PC | 1 |
| Leaming, AB | 1 |
| McCullagh, KG | 1 |
| Ehrhart, A | 1 |
| Butkus, A | 1 |
| Hoang-Vu, C | 1 |
| Dralle, H | 1 |
| Schröder, S | 1 |
| Oertel, M | 1 |
| Hesch, RD | 1 |
| von zur Mühlen, A | 1 |
| Brabant, G | 1 |
| Dagogo-Jack, S | 1 |
| Cihák, R | 1 |
| Kolár, F | 1 |
| Pelouch, V | 1 |
| Procházka, J | 1 |
| Ostádal, B | 1 |
| Widimský, J | 1 |
| Samuels, MH | 1 |
| Ridgway, EC | 1 |
| Porterfield, SP | 1 |
| Hendrich, CE | 1 |
| Sundick, RS | 3 |
| Herdegen, D | 1 |
| Brown, TR | 1 |
| Dhar, A | 1 |
| Bagchi, N | 1 |
| Rom-Bugoslavskaia, ES | 1 |
| Bondarenko, LA | 1 |
| Fong, P | 1 |
| Kendler, D | 1 |
| Thung, S | 1 |
| Calvo, R | 1 |
| Ruiz de Oña, C | 1 |
| Ferreiro, B | 1 |
| Escobar Del Rey, E | 1 |
| Gottesfeld, Z | 1 |
| Silverman, PB | 1 |
| Karsanov, NV | 1 |
| Melashvili, NO | 1 |
| Khugashvili, ZG | 1 |
| Mamulashvili, LD | 1 |
| Azrumelashvili, MI | 1 |
| Khaindrava, GK | 1 |
| Kapanadze, RV | 1 |
| Vriend, J | 1 |
| Sheppard, MS | 1 |
| Bala, RM | 1 |
| Prulière, G | 1 |
| Butler-Browne, GS | 2 |
| Cambon, N | 1 |
| Toutant, M | 2 |
| Whalen, RG | 2 |
| Pokotilenko, GM | 1 |
| Poliachenko, LIu | 1 |
| Varnum, B | 1 |
| Davidson, MB | 1 |
| Venkatesan, N | 1 |
| Conger, JD | 1 |
| Falk, SA | 1 |
| Gillum, DM | 1 |
| Lothrop, CD | 1 |
| Coulson, PA | 1 |
| Nolan, HL | 1 |
| Cole, B | 1 |
| Jones, JB | 1 |
| Sanders, WL | 1 |
| Kuang, AK | 1 |
| Chen, JL | 1 |
| Fabris, N | 1 |
| Mocchegiani, E | 1 |
| Muzzioli, M | 1 |
| Provinciali, M | 1 |
| Baksi, SN | 1 |
| Kawada, J | 1 |
| Mino, H | 1 |
| Nishida, M | 1 |
| Yoshimura, Y | 1 |
| Stein-Streilein, J | 1 |
| Zakarija, M | 1 |
| Papic, M | 1 |
| McKenzie, JM | 1 |
| Barsano, CP | 1 |
| Burke, SF | 1 |
| Quintana, M | 1 |
| Quintanilla, A | 1 |
| Iqbal, Z | 1 |
| Munoz, E | 1 |
| Mano, MT | 1 |
| Watkins, SC | 1 |
| Holt, AB | 1 |
| Cheek, DB | 1 |
| Kerr, GR | 1 |
| Schulte-Wissermann, H | 1 |
| Straub, E | 4 |
| Wick, G | 2 |
| Albini, B | 1 |
| Wildenthal, K | 1 |
| Mueller, EA | 1 |
| Cohen, J | 1 |
| Voss, C | 1 |
| Lorenz, C | 1 |
| Ratzmann, L | 1 |
| Hartmann, N | 1 |
| DePalma, RG | 1 |
| Insull, W | 1 |
| Bellon, EM | 1 |
| Roth, WT | 1 |
| Robinson, AV | 1 |
| Korecky, B | 1 |
| Taichman, GC | 1 |
| Minelli, R | 1 |
| Beznak, M | 1 |
| Berk, SL | 1 |
| Ullrick, WC | 1 |
| Klawans, HL | 1 |
| Goetz, CH | 1 |
| Weiner, WJ | 1 |
| Deol, MS | 1 |
| Pelton, EW | 1 |
| Bass, NH | 1 |
| Matovinovic, J | 1 |
| Nishiyama, RH | 1 |
| Poissant, G | 1 |
| Schurr, PE | 1 |
| Schultz, JR | 1 |
| Parkinson, TM | 1 |
| Edwards, KD | 1 |
| Usardi, MM | 1 |
| Galli, C | 1 |
| Paoletti, R | 1 |
| Ashkar, FS | 1 |
| Katims, RB | 1 |
| Smoak, WM | 1 |
| Gilson, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction[NCT02512978] | Phase 4 | 160 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for thyroxine and Disease Models, Animal
| Article | Year |
|---|---|
Thyroid replacement therapy and heart failure.
Topics: Animals; Cardiovascular Diseases; Diiodothyronines; Disease Models, Animal; Glomerular Filtration Ra | 2010 |
Thyroid hormones and fetal brain development.
Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus; | 2005 |
Thyroid hormones, learning and memory.
Topics: Animals; Cognition; Disease Models, Animal; Female; Humans; Learning; Memory; Mice; Mice, Transgenic | 2007 |
[Influence of thyroliberin on vasopressin and oxytocin release from the hypothalamo-neurohypophysial system under in vivo and in vitro conditions].
Topics: Animals; Dehydration; Disease Models, Animal; Dogs; Female; Humans; Hypothalamo-Hypophyseal System; | 2007 |
Inherited disorders of thyroid metabolism.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Diagnosis, Differential; Disease Models, Animal | 1983 |
Autoantigens in thyroid diseases.
Topics: Amino Acid Sequence; Animals; Autoantigens; Autoimmunity; Disease Models, Animal; Epitopes; Humans; | 1993 |
Autoimmune thyroiditis--spontaneous disease models--cat.
Topics: Animals; Cats; Disease Models, Animal; Iodine; Thyroiditis, Autoimmune; Thyroxine | 1996 |
Neuroendocrine-thymus interactions: perspectives for intervention in aging.
Topics: Aging; Animals; Disease Models, Animal; Dwarfism, Pituitary; Humans; Immune System; Immunologic Defi | 1988 |
A review: The obese strain (OS) of chickens: an animal model with spontaneous autoimmune thyroiditis.
Topics: Adenosine; Animals; Animals, Newborn; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Basement M | 1974 |
2 trials available for thyroxine and Disease Models, Animal
| Article | Year |
|---|---|
Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
Topics: Animals; Animals, Newborn; Cerebral Hemorrhage; Cerebral Ventricles; Disease Models, Animal; Double- | 2013 |
Expression of thyroid hormone transporters during critical illness.
Topics: Aged; Amino Acid Transport Systems, Neutral; Animals; Base Sequence; Critical Illness; Disease Model | 2009 |
367 other studies available for thyroxine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome.
Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Female; Gene Expression; Gene Expression R | 2022 |
Functional State of Rat Heart Mitochondria in Experimental Hyperthyroidism.
Topics: Animals; Disease Models, Animal; Hyperthyroidism; Lipid Peroxidation; Male; Mitochondria, Heart; Oxi | 2021 |
The Nutritional Supply of Iodine and Selenium Affects Thyroid Hormone Axis Related Endpoints in Mice.
Topics: Animals; Disease Models, Animal; Homeostasis; Iodine; Kidney; Liver; Mice; Nutritional Status; Selen | 2021 |
Neuroprotection of reduced thyroid hormone with increased estrogen and progestogen in postpartum depression.
Topics: Adult; Animals; Antithyroid Agents; Basolateral Nuclear Complex; Body Weight; Brain-Derived Neurotro | 2019 |
Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Diiodothyronines; Disease Models, Animal | 2019 |
Propranolol inhibits myocardial infarction-induced brown adipose tissue D2 activation and maintains a low thyroid hormone state in rats.
Topics: Adipose Tissue, Brown; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Iodide Peroxida | 2019 |
Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Di | 2019 |
Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis.
Topics: Animals; Antithyroid Agents; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, | 2020 |
Effects of levothyroxine on lung inflammation, oxidative stress and pathology in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Male; Oxidative Stress; Pneumonia; Rats; Rats, W | 2020 |
Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism.
Topics: Animals; Catalase; Disease Models, Animal; Electron Transport Chain Complex Proteins; Energy Metabol | 2020 |
Thyroid Function Modulates Lung Fluid and Alveolar Viscoelasticity in Mechanically Ventilated Rat.
Topics: Animals; Antithyroid Agents; Aquaporin 5; Disease Models, Animal; Elasticity; Humans; Male; Methimaz | 2020 |
Experimental hypothyroidism raises brain kynurenic acid - Novel aspect of thyroid dysfunction.
Topics: Animals; Brain; Disease Models, Animal; Hypothyroidism; Kynurenic Acid; Male; Propylthiouracil; Rats | 2020 |
Effects of Carvedilol and Thyroid Hormones Co-administration on Apoptotic and Survival Proteins in the Heart After Acute Myocardial Infarction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carvedil | 2020 |
A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model.
Topics: Adenocarcinoma; Animals; Apoptosis; Body Weight; Cell Proliferation; Disease Models, Animal; Male; M | 2020 |
Neuroprotection elicited by resveratrol in a rat model of hypothyroidism: Possible involvement of cholinergic signaling and redox status.
Topics: Acetylcholinesterase; Animals; Antigens, Nuclear; Cholinergic Agents; Disease Models, Animal; Glial | 2021 |
A Blunted Sympathetic Function and an Enhanced Nitrergic Activity Contribute to Reduce Mesenteric Resistance in Hyperthyroidism.
Topics: Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Electric Stimulation; Humans; Hyperthy | 2021 |
Maternal L-thyroxine treatment during lactation affects learning and anxiety-like behaviors but not spatial memory in adult rat progeny.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Female; Hippocampus; Hyperthyroidism; La | 2021 |
Thyroid Hormones Regulate Goblet Cell Differentiation and Fgf19-Fgfr4 Signaling.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Fibroblast Growth Factors; Goblet Cells; Humans | 2021 |
Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model.
Topics: Animals; Calgranulin B; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependen | 2021 |
Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism.
Topics: Animals; Animals, Genetically Modified; Congenital Hypothyroidism; CRISPR-Cas Systems; Disease Model | 2021 |
Acylated Ghrelin Attenuates l-Thyroxin-induced Cardiac Damage in Rats by Antioxidant and Anti-inflammatory Effects and Downregulating Components of the Cardiac Renin-angiotensin System.
Topics: Acylation; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Ghrelin; Hyperth | 2021 |
Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism.
Topics: Animals; Depression; Disease Models, Animal; Drug Therapy, Combination; Frontal Lobe; Humans; Hypoth | 2021 |
Pre-existing Thyroiditis Ameliorates Papillary Thyroid Cancer: Insights From a New Mouse Model.
Topics: Animals; Antigens, CD19; CD8-Positive T-Lymphocytes; Crosses, Genetic; Disease Models, Animal; Femal | 2021 |
Age-dependent response to T4 overtreatment and recovery on systemic and organ level.
Topics: Age Factors; Animals; Biomarkers; Disease Management; Disease Models, Animal; Hypothyroidism; Lipid | 2021 |
Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy.
Topics: Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Disease Progression; Iodide Peroxidase; Mi | 2017 |
Simultaneous induction of Graves' hyperthyroidism and Graves' ophthalmopathy by TSHR genetic immunization in BALB/c mice.
Topics: 3T3 Cells; Animals; Autoantibodies; Disease Models, Animal; Electroporation; Enzyme-Linked Immunosor | 2017 |
Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Brain Edema; Brain Injuries; Cell | 2017 |
Is centrally induced alveolar bone loss in a large animal model preventable by peripheral hormone substitution?
Topics: Alveolar Bone Loss; Animals; Disease Models, Animal; Estrogens; Female; Mandible; Ovariectomy; Rando | 2018 |
Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.
Topics: Animals; Apoptosis; Cattle; Cellular Senescence; Disease Models, Animal; DNA Damage; Enzyme Activati | 2018 |
The regulation of pituitary-thyroid abnormalities by peripheral administration of levothyroxine increased brain-derived neurotrophic factor and reelin protein expression in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain-Derived Neurotrophic Factor; Cell Adhesion Molecules, Neuronal; Di | 2018 |
Both experimental hypothyroidism and hyperthyroidism increase cardiac irisin levels in rats.
Topics: Animals; Disease Models, Animal; Fibronectins; Heart; Heart Diseases; Hyperthyroidism; Hypothyroidis | 2018 |
Synthesis of new analogs of tetraiodothyroacetic acid (tetrac) as novel angiogenesis inhibitors for treatment of cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; | 2018 |
Thyroid Dysfunction, Neurological Disorder and Immunosuppression as the Consequences of Long-term Combined Stress.
Topics: Animals; Blood; Colitis, Ulcerative; Colon; Disease Models, Animal; Gene Expression Profiling; Hypot | 2018 |
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele | 2018 |
Effects of Thyroid Dysfunction on Reproductive Hormones in Female Rats.
Topics: Animals; Biomarkers; Cholesterol Side-Chain Cleavage Enzyme; Disease Models, Animal; Estradiol; Estr | 2018 |
Effects of levothyroxine on learning and memory deficits in a rat model of Alzheimer's disease: the role of BDNF and oxidative stress.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Disease Models, A | 2020 |
Cystathionine beta synthase-hydrogen sulfide system in paraventricular nucleus reduced high fatty diet induced obesity and insulin resistance by brain-adipose axis.
Topics: Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Cystathionine beta-Synthase; Diet, High-F | 2018 |
Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Colorectal Neoplasms; Disease Mo | 2018 |
Therapeutic Effects of Short Cyclic and Combined Epitope Peptides in a Long-Term Model of Graves' Disease and Orbitopathy.
Topics: Adenoviridae; Animals; Disease Models, Animal; Epitopes; Female; Fibrosis; Graves Ophthalmopathy; HE | 2019 |
UNEQUAL HORMONAL RESPONSE OF MALE AND FEMALE C3H-A MICE TO THE THYROID AND ANTITHYROID AGENT TREATMENTS.
Topics: Animals; Antithyroid Agents; Disease Models, Animal; Female; Hyperthyroidism; Hypothyroidism; Male; | 2018 |
Local hyperthyroidism promotes pancreatic acinar cell proliferation during acute pancreatitis.
Topics: Acinar Cells; Animals; Cell Proliferation; Ceruletide; Disease Models, Animal; Histone Deacetylases; | 2019 |
Impaired Glucose Metabolism in Young Offspring of Female Rats with Hypothyroidism.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Cell Proliferation; Disease Models, Animal; Female; | 2019 |
Effects of exogenous melatonin on clinical and pathological features of a human thyroglobulin-induced experimental autoimmune thyroiditis mouse model.
Topics: Animals; Autoantibodies; Cell Proliferation; Disease Models, Animal; Female; Humans; Melatonin; Mice | 2019 |
Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Benzoquinones; Disease Models, Animal; Hashimoto Disease | 2019 |
Post-ischaemic thyroid hormone treatment in a rat model of acute stroke.
Topics: Animals; Brain Infarction; Brain-Derived Neurotrophic Factor; Calcium-Binding Proteins; Cyclooxygena | 2013 |
Restoration of cardiac tissue thyroid hormone status in experimental hypothyroidism: a dose-response study in female rats.
Topics: Animals; Disease Models, Animal; Female; Heart; Hypothyroidism; Myocardium; Rats; Rats, Sprague-Dawl | 2013 |
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Pro | 2013 |
Thyroxin treatment protects against white matter injury in the immature brain via brain-derived neurotrophic factor.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Anim | 2013 |
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD).
Topics: Animals; Disease Models, Animal; Estradiol; Fracture Healing; Hypothalamus; Osteoporotic Fractures; | 2013 |
Effects of hypo- and hyperthyroid states on herpes simplex virus infectivity in the rat.
Topics: Animals; Antithyroid Agents; Chlorocebus aethiops; Disease Models, Animal; Herpes Simplex; Herpesvir | 2014 |
[Evaluation of the key indicators in the pituitary-target gland axes in the animal model with shenyang deficiency syndrome using factor analysis].
Topics: Animals; Disease Models, Animal; Estradiol; Factor Analysis, Statistical; Follicle Stimulating Hormo | 2013 |
Hyperthyroid monkeys: a nonhuman primate model of experimental Graves' disease.
Topics: Animals; Antigens; Autoantibodies; Biomarkers; Disease Models, Animal; Female; Gene Transfer Techniq | 2013 |
Thyroid hormone-dependent development of the GABAergic pre- and post-synaptic components in the rat hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Gen | 2013 |
Levothyroxin replacement therapy restores hypothyroidism induced impairment of L-LTP induction: critical role of CREB.
Topics: Animals; Blotting, Western; CA1 Region, Hippocampal; Cyclic AMP Response Element-Binding Protein; Di | 2014 |
Failure of thyroid hormone treatment to prevent inflammation-induced white matter injury in the immature brain.
Topics: Animals; Brain; Disease Models, Animal; Encephalitis; Gene Expression; Interleukin-1beta; Male; Mice | 2014 |
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal | 2013 |
Thyroid hormones regulate anxiety in the male mouse.
Topics: Animals; Anxiety; Conditioning, Classical; Disease Models, Animal; Fear; Hypothyroidism; Male; Methi | 2014 |
Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study.
Topics: Acute Disease; Animals; Antithyroid Agents; Cells, Cultured; Cerebral Cortex; Disease Models, Animal | 2015 |
Lawsonia inermis - an alternative treatment for hyperthyroidism?
Topics: Animals; Disease Models, Animal; Female; Hydrogen-Ion Concentration; Hyperthyroidism; Lawsonia Plant | 2014 |
The effects of subclinical hypothyroidism on serum lipid level and TLR4 expression of monocyte in peripheral blood of rats.
Topics: Animals; Cholesterol; Cholesterol, LDL; Cytokines; Disease Models, Animal; Female; Flow Cytometry; H | 2014 |
Short-term thyroid hormone excess affects the heart but does not affect adrenal activity in rats.
Topics: Adrenal Glands; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Echocardiography; H | 2014 |
Embryonic protein undernutrition by albumen removal programs the hepatic amino acid and glucose metabolism during the perinatal period in an avian model.
Topics: Albumins; Amino Acids; Animals; Animals, Newborn; Avian Proteins; Chick Embryo; Chickens; Disease Mo | 2014 |
Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Glutathione Disulfide; | 2014 |
Decreased pain threshold and enhanced synaptic transmission in the anterior cingulate cortex of experimental hypothyroidism mice.
Topics: Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gyrus Cinguli; Hyperalgesia; Hy | 2014 |
Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats.
Topics: Analysis of Variance; Animals; Brain; CD11b Antigen; CD4-Positive T-Lymphocytes; Disease Models, Ani | 2014 |
Thyroid hormone replacement therapy attenuates atrial remodeling and reduces atrial fibrillation inducibility in a rat myocardial infarction-heart failure model.
Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Electrocardiography; Female | 2014 |
Effects of thyroxine treatment on histology and behavior using the methimazole model of congenital hypothyroidism in the rat.
Topics: Animals; Conditioning, Operant; Congenital Hypothyroidism; Dendrites; Disease Models, Animal; Female | 2015 |
Thermogenesis and longevity in mammals. Thyroxin model of accelerated aging.
Topics: Aging; Aging, Premature; Animals; Antioxidants; Disease Models, Animal; Glutathione; Hyperthyroidism | 2014 |
Prolonged TSH receptor A subunit immunization of female mice leads to a long-term model of Graves' disease, tachycardia, and cardiac hypertrophy.
Topics: Adenoviridae; Animals; Autoantibodies; Cardiomegaly; Disease Models, Animal; Female; Graves Disease; | 2015 |
Effects of 3,3',5-triiodothyronine on microglial functions.
Topics: Adenosine Triphosphate; Adjuvants, Pharmaceutic; Animals; Brain Injuries; Cell Movement; Cells, Cult | 2015 |
Levothyroxine replacement therapy with vitamin E supplementation prevents the oxidative stress and apoptosis in hippocampus of hypothyroid rats.
Topics: Animals; Apoptosis; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Hippocam | 2014 |
Low thyroid hormone levels improve survival in murine model for ocular melanoma.
Topics: Animals; Antithyroid Agents; Disease Models, Animal; Eye Neoplasms; Hyperthyroidism; Hypothyroidism; | 2015 |
Endothelial Functioning and Hemodynamic Parameters in Rats with Subclinical Hypothyroid and the Effects of Thyroxine Replacement.
Topics: Animals; Aorta; Blood Pressure; Body Weight; Cholesterol; Cholesterol, LDL; Disease Models, Animal; | 2015 |
T3 and T4 decrease ROS levels and increase endothelial nitric oxide synthase expression in the myocardium of infarcted rats.
Topics: Animals; Disease Models, Animal; Heart Ventricles; Male; Myocardial Infarction; Nitric Oxide; Nitric | 2015 |
Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization.
Topics: Animals; Antioxidants; Asymptomatic Diseases; Behavior, Animal; Brain-Derived Neurotrophic Factor; D | 2015 |
Alterations in Thyroid Hormones Due to Increased Intraabdominal Pressure in Rats.
Topics: Abdomen; Animals; Disease Models, Animal; Female; Intra-Abdominal Hypertension; Lower Body Negative | 2015 |
Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency.
Topics: Animals; Biopterins; Brain; Catecholamines; Disease Models, Animal; Dopamine Agents; Eating; Female; | 2015 |
Maternal hyperthyroidism increases the susceptibility of rat adult offspring to cardiovascular disorders.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibi | 2015 |
Thyroid disrupting effects of polychlorinated biphenyls in ovariectomized rats: A benchmark dose analysis.
Topics: Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Female; No-Observed- | 2015 |
β1-Adrenergic and M2 Muscarinic Autoantibodies and Thyroid Hormone Facilitate Induction of Atrial Fibrillation in Male Rabbits.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Antigens; Atrial Fibrillation; Autoantibodies; Coronar | 2016 |
[Effect of Jiakangning Capsule on Thyroid Function and Akt/mTOR Signal Pathway of Graves' Disease Mice: an Experimental Study].
Topics: Actins; Animals; Capsules; Disease Models, Animal; Drugs, Chinese Herbal; Female; Graves Disease; Me | 2015 |
Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats.
Topics: Animals; Antithyroid Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Conditioning, Psyc | 2016 |
Anti-Inflammatory Role of Thyroid Hormones on Rat Air Pouch Model of Inflammation.
Topics: Air; Animals; Anti-Infective Agents; Carrageenan; Disease Models, Animal; Glutathione; Inflammation; | 2015 |
Hypothyroidism Impairs Human Stem Cell-Derived Pancreatic Progenitor Cell Maturation in Mice.
Topics: Animals; Antithyroid Agents; Biomarkers; Cell Differentiation; Cell Line; Cells, Immobilized; Diabet | 2016 |
Development of a Novel Thyroid Function Fluctuated Animal Model for Thyroid-Associated Ophthalmopathy.
Topics: Animals; Body Weight; Disease Models, Animal; Drug Administration Schedule; Endoplasmic Reticulum; G | 2016 |
The Effect of Sorafenib, Tadalafil and Macitentan Treatments on Thyroxin-Induced Hemodynamic Changes and Cardiac Abnormalities.
Topics: Animals; Blood Pressure; Cardiomyopathies; Disease Models, Animal; Echocardiography; Electrocardiogr | 2016 |
Low-frequency stimulation induces a durable long-term depression in young adult hyperthyroid rats: the role of p38 mitogen-activated protein kinase and protein phosphatase 1.
Topics: Animals; Biophysics; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Gene Expression Re | 2016 |
Establishment and evaluation of a mouse model of bronchial asthma with Yin deficiency syndrome.
Topics: Animals; Asthma; Bronchi; Disease Models, Animal; Mice; Ovalbumin; Thyroxine; Yin Deficiency | 2015 |
Perinatal Iron Deficiency-Induced Hypothyroxinemia Impairs Early Brain Development Regardless of Normal Iron Levels in the Neonatal Brain.
Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Behavior, Animal; Brain; Cerebral Cortex; Diseas | 2016 |
Opposing Effects of Maternal Hypo- and Hyperthyroidism on the Stability of Thalamocortical Synapses in the Visual Cortex of Adult Offspring.
Topics: Adult; Animals; Animals, Newborn; Antithyroid Agents; Brain Mapping; Disease Models, Animal; Female; | 2017 |
The Effect of Experimental Thyroid Dysfunction on Markers of Oxidative Stress in Rat Pancreas.
Topics: Animals; Antioxidants; Biomarkers; Disease Models, Animal; Glutathione; Hyperthyroidism; Hypothyroid | 2016 |
Adult-onset hyperthyroidism impairs spatial learning: possible involvement of mitogen-activated protein kinase signaling pathways.
Topics: Animals; CREB-Binding Protein; Disease Models, Animal; Hippocampus; Hyperthyroidism; Learning Disabi | 2016 |
SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model.
Topics: Adenocarcinoma, Follicular; Animals; Carcinogenesis; Disease Models, Animal; Hydroxamic Acids; Mice, | 2016 |
Effects of Thyroxine (T4), 3,5,3'-triiodo-L-thyronine (T3) and their Metabolites on Osteoblast Differentiation.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Bone and Bones; Cell Differentiation; Cell Line; Disease M | 2016 |
Effect of Fetal Hypothyroidism on Cardiac Myosin Heavy Chain Expression in Male Rats.
Topics: Animals; Antithyroid Agents; Body Weight; Congenital Hypothyroidism; Disease Models, Animal; DNA, Co | 2016 |
Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis.
Topics: Abnormalities, Drug-Induced; Animals; Craniosynostoses; Disease Models, Animal; Gene Expression Regu | 2016 |
T3 enhances Ang2 in rat aorta in myocardial I/R: comparison with left ventricle.
Topics: Angiopoietin-2; Animals; Aorta; Disease Models, Animal; Echocardiography; Endothelial Cells; Gene Ex | 2016 |
Efficacy of protocols for induction of chronic hyperthyroidism in male and female mice.
Topics: Animals; Disease Models, Animal; Female; Hyperthyroidism; Male; Mice; Sex Factors; Thyroxine | 2016 |
Sepsis leads to thyroid impairment and dysfunction in rat model.
Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression Regulation; Humans; Rats; Sepsis; Thyroi | 2016 |
New Murine Model of Early Onset Autoimmune Thyroid Disease/Hypothyroidism and Autoimmune Exocrinopathy of the Salivary Gland.
Topics: Animals; Autoimmune Diseases; CD28 Antigens; CD40 Antigens; Cells, Cultured; Disease Models, Animal; | 2016 |
Central and peripheral administrations of levothyroxine improved memory performance and amplified brain electrical activity in the rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain; Disease Models, Animal; Hippocampus; Neurons; | 2016 |
In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish.
Topics: Anemia; Animals; Animals, Genetically Modified; Brain Edema; Congenital Hypothyroidism; Craniofacial | 2017 |
Maternal High Estradiol Exposure is Associated with Elevated Thyroxine and Pax8 in Mouse Offspring.
Topics: Animals; CpG Islands; Disease Models, Animal; DNA Methylation; Estradiol; Female; Genetic Markers; M | 2016 |
Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke.
Topics: Animals; Blotting, Western; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cytokines; Disease Mo | 2017 |
A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes.
Topics: Adipocytes, Brown; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cells, Cultured; Cytoplasm | 2017 |
Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model.
Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Resorption; Disease Models, Ani | 2017 |
An improved method for the establishment of a model of Graves' disease in BALB/c mice.
Topics: Animals; Disease Models, Animal; Female; Graves Disease; Humans; Immunization; Mice, Inbred BALB C; | 2017 |
The effects of low thyroid hormone levels on the formation of stress gastritis: an experimental study on the rats.
Topics: Animals; Disease Models, Animal; Euthyroid Sick Syndromes; Gastritis; Hypothyroidism; Male; Rats; Ra | 2008 |
Histomorphometry and expression of CDC-47 and caspase-3 in mammary glands of pregnant female rats with artificial hyperthyroidism.
Topics: Adenosine Triphosphatases; Animals; Apoptosis; Caspase 3; Cell Proliferation; Disease Models, Animal | 2008 |
Developmental neurotoxicity of propylthiouracil (PTU) in rats: relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes.
Topics: Age Factors; Animals; Animals, Newborn; Antithyroid Agents; Auditory Threshold; Behavior, Animal; Bo | 2008 |
An animal model to study health effects during continuous low-dose exposure to the nerve agent VX.
Topics: Acetylcholinesterase; Animals; Blood Pressure; Chemical Warfare Agents; Cholinesterase Inhibitors; C | 2008 |
Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Aspartic Acid Endopeptidases; Berberine; Cardiomegaly | 2008 |
Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; AMP-Activated Protein K | 2008 |
Downregulated FKBP12.6 expression and upregulated endothelin signaling contribute to elevated diastolic calcium and arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin.
Topics: Animals; Calcium; Cardiomyopathy, Hypertrophic; Diastole; Disease Models, Animal; Down-Regulation; E | 2008 |
Increased fetal abortion rate in autoimmune thyroid disease is related to circulating TPO autoantibodies in an autoimmune thyroiditis animal model.
Topics: Abortion, Spontaneous; Animals; Autoantibodies; Blastocyst; Disease Models, Animal; Female; Iodide P | 2009 |
Thyroxine treatment stimulated ovarian follicular angiogenesis in immature hypothyroid rats.
Topics: Angiogenic Proteins; Animals; Chorionic Gonadotropin; Corrosion Casting; Disease Models, Animal; Fem | 2008 |
The role of redox signaling in cardiac hypertrophy induced by experimental hyperthyroidism.
Topics: Animals; Ascorbic Acid; Blotting, Western; Cardiomegaly; Disease Models, Animal; Glutathione; Hydrog | 2008 |
Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.
Topics: Animals; CD24 Antigen; Disease Models, Animal; Female; Mice; Mice, Inbred DBA; Proliferating Cell Nu | 2009 |
[Apoptosis, proliferation and spleen histomorphometry of adult female rats with thyroid and ovarian hypofunction].
Topics: Adenosine Triphosphatases; Animals; Antithyroid Agents; Apoptosis; Caspase 3; Cell Proliferation; Di | 2008 |
Levothyroxin inhibits heterotopic ossification: an experimental study in rabbits.
Topics: Administration, Oral; Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, D | 2008 |
Congenital hypothyroidism alters formalin-induced pain response in neonatal rats.
Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Central Nervous System; Congenital Hypothyroidi | 2009 |
An experimental approach to the interrelationship between hyperthyroidism and ejaculation latency time in male rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Ejaculation; Hyperthyroidism; Injections, Int | 2009 |
[Renin-angiotensin system blocking agents reverse the myocardial hypertrophy in experimental hyperthyroid cardiomyopathy via altering intracellular calcium handling].
Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Disease Models, Animal; Hyperthyroidism; Imida | 2008 |
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres | 2009 |
[Thyroid-induced hyperthyroidism Yin-deficiency model of rats].
Topics: Animals; Disease Models, Animal; Female; Hyperthyroidism; Male; Radioimmunoassay; Random Allocation; | 2008 |
Thyroxine as a stimulator of liver regeneration after partial hepatectomy: an experimental animal study.
Topics: Animals; Cyclin D; Cyclins; Disease Models, Animal; Hepatectomy; Liver; Liver Regeneration; Male; Ra | 2008 |
Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function.
Topics: Angiogenesis Inducing Agents; Animals; Body Temperature; Coronary Vessels; Diiodothyronines; Disease | 2009 |
Immunization with thyroglobulin induces Graves'-like disease in mice.
Topics: Animals; Autoantibodies; Cattle; Disease Models, Animal; Female; Graves Disease; Immunization; Immun | 2009 |
Role of late maternal thyroid hormones in cerebral cortex development: an experimental model for human prematurity.
Topics: Animals; Animals, Newborn; Body Patterning; Brain; Developmental Disabilities; Disease Models, Anima | 2010 |
Developmental changes of cone opsin expression but not retinal morphology in the hypothyroid Pax8 knockout mouse.
Topics: Animals; Biomarkers; Body Weight; Cone Opsins; Congenital Hypothyroidism; Disease Models, Animal; Fe | 2010 |
Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice.
Topics: Animals; Antibodies, Monoclonal; Cell Count; Cell Movement; Chemokine CCL11; Chemokine CXCL1; Diseas | 2010 |
Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits.
Topics: Actins; Animals; Blood Glucose; Body Weight; Critical Illness; Disease Models, Animal; Glucose; Hype | 2010 |
Methimazole-induced hypothyroidism inhibits the panic-like behaviors produced by electrical stimulation of dorsal periaqueductal gray matter of rats.
Topics: Animals; Anxiety; Disease Models, Animal; Electric Stimulation; Hypothyroidism; Male; Maze Learning; | 2010 |
Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.
Topics: Amygdala; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Depressive Disorder; Di | 2010 |
The relationship between cyclic changes in thyroid function and behavior of cats with brain stem lesions.
Topics: Animals; Behavior, Animal; Brain Injuries; Brain Stem; Cats; Circadian Rhythm; Disease Models, Anima | 1967 |
Thyroid hormone modulates the responsiveness of rat aorta to alpha1-adrenergic stimulation: an effect due to increased activation of beta2-adrenergic signaling.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Re | 2009 |
Comparisons of the effects of systemic administration of L-thyroxine and doxycycline on orthodontically induced root resorption in rats.
Topics: Animals; Bone Density Conservation Agents; Disease Models, Animal; Doxycycline; Drug Combinations; E | 2010 |
Is the mechanisms of fipronil-induced thyroid disruption specific of the rat: Re-evaluation of fipronil thyroid toxicity in sheep?
Topics: Animals; Area Under Curve; Disease Models, Animal; Female; Insecticides; Male; Pyrazoles; Random All | 2010 |
Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma.
Topics: Adenocarcinoma, Follicular; Animals; Blotting, Western; Cell Proliferation; Disease Models, Animal; | 2010 |
Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Disease Models, A | 2010 |
Maternal thyroid hormone before the onset of fetal thyroid function regulates reelin and downstream signaling cascade affecting neocortical neuronal migration.
Topics: Animals; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Cell Movement; Disease Models, Ani | 2011 |
Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats.
Topics: Animals; Antithyroid Agents; Brain; Cell Differentiation; Disease Models, Animal; Female; Humans; Hy | 2010 |
The effect of maternal subclinical hypothyroidism during pregnancy on brain development in rat offspring.
Topics: Animals; Brain; Disease Models, Animal; Female; Hippocampus; Hypothyroidism; Maze Learning; Pregnanc | 2010 |
Absence of primary hypothyroidism and goiter in Slc26a4 (-/-) mice fed on a low iodine diet.
Topics: Animals; Anion Transport Proteins; Diet; Disease Models, Animal; Goiter; Goiter, Nodular; Hearing Lo | 2011 |
Changes in gene expression of DOR and other thyroid hormone receptors in rat liver during acute-phase response.
Topics: Acute-Phase Reaction; Animals; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; G | 2010 |
[Effect of Chrysanthemum indicum on ventricular remodeling in rats].
Topics: Aldosterone; Angiotensin II; Animals; Chrysanthemum; Disease Models, Animal; Drugs, Chinese Herbal; | 2010 |
Experience with lentivirus-mediated CD40 gene silencing in a mouse model of Graves' disease.
Topics: Adenoviridae; Animals; B7-1 Antigen; B7-2 Antigen; CD40 Antigens; Disease Models, Animal; Female; Fo | 2011 |
B cell-targeted therapy with anti-CD20 monoclonal antibody in a mouse model of Graves' hyperthyroidism.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD20; B-Lymphocytes; Cell Count; Disease Models, Animal; | 2011 |
Experimentally induced hyperthyroidism disrupts hippocampal long-term potentiation in adult rats.
Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Electrophysiological Phenomena; Hipp | 2011 |
Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase.
Topics: Aminopeptidases; Animals; Antithyroid Agents; Disease Models, Animal; Hypothyroidism; Injections, In | 2011 |
[Nourishing-yin effect and mechanism of different parts of Cornu Elaphuri Davidiani in rats].
Topics: Adrenocorticotropic Hormone; Animals; Antlers; Deer; Disease Models, Animal; Estradiol; Ethanol; Fem | 2011 |
Impact of L-NAME on the cardiopulmonary reflex in cardiac hypertrophy.
Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Caffeine; Cardiomegaly; Disease Models, Animal; D | 2011 |
Social stress-induced hypothyroidism is attenuated by antidepressant treatment in rats.
Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Corticoste | 2012 |
The significance of immune-related molecule expression profiles in an animal model of Graves' disease.
Topics: Adenoviridae; Animals; B7-2 Antigen; CD40 Antigens; Disease Models, Animal; Female; Gene Expression | 2012 |
Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac).
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Cell Surviva | 2012 |
Dose-dependent effects of thyroid hormone on post-ischemic cardiac performance: potential involvement of Akt and ERK signalings.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MA | 2012 |
Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study.
Topics: Animals; Constitutive Androstane Receptor; Critical Illness; Disease Models, Animal; Dithiothreitol; | 2012 |
Mice deficient in dual oxidase maturation factors are severely hypothyroid.
Topics: Animals; Disease Models, Animal; Dual Oxidases; Female; Gene Knockout Techniques; Growth Disorders; | 2012 |
The feline thyroid gland: a model for endocrine disruption by polybrominated diphenyl ethers (PBDEs)?
Topics: Animal Feed; Animals; Cat Diseases; Cats; Disease Models, Animal; Dust; Endocrine Disruptors; Enviro | 2012 |
Curcumin differentially regulates the expression of superoxide dismutase in cerebral cortex and cerebellum of L-thyroxine (T₄)-induced hyperthyroid rat brain.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebellum; Cerebral Cortex; | 2013 |
Thyroid hormone accelerates the differentiation of adult hippocampal progenitors.
Topics: Animals; Cell Count; Cells, Cultured; Disease Models, Animal; Doublecortin Protein; Gene Expression | 2012 |
Experimental hyperthyroidism decreases gene expression and serum levels of adipokines in obesity.
Topics: Adiponectin; Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Gene Expression Regulatio | 2012 |
Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: II-the developmental pattern of neurons in relation to oxidative stress and antioxidant defense system.
Topics: Age Factors; alpha-Tocopherol; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Ascorb | 2012 |
Genetic linkages for thyroxine released in response to thyrotropin stimulation in three sets of recombinant inbred mice provide evidence for shared and novel genes controlling thyroid function.
Topics: Animals; Cattle; Crosses, Genetic; Disease Models, Animal; Female; Genetic Linkage; Graves Disease; | 2013 |
Levothyroxine replacement therapy with vitamin E supplementation prevents oxidative stress and cognitive deficit in experimental hypothyroidism.
Topics: Animals; Cognition Disorders; Dietary Supplements; Disease Models, Animal; Hippocampus; Hormone Repl | 2013 |
Generation of functional thyroid from embryonic stem cells.
Topics: Animals; Cell Differentiation; Disease Models, Animal; Embryonic Stem Cells; Female; Humans; Hypothy | 2012 |
Effects of adult dysthyroidism on the morphology of hippocampal granular cells in rats.
Topics: Analysis of Variance; Animals; Antithyroid Agents; Disease Models, Animal; Hippocampus; Hyperthyroid | 2012 |
Heart rate reduction with ivabradine prevents thyroid hormone-induced cardiac remodeling in rat.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Calcium Signaling; Disease Models, Animal; Fibrosis; | 2013 |
Role of L-thyroxin in counteracting rotenone induced neurotoxicity in rats.
Topics: Animals; Catalepsy; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Microglia; Neurop | 2013 |
Hypoxic preconditioning increases triiodothyronine (T3) level in the developing rat brain.
Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Female; Hypoxia-Ischemia, Brain; Ischemic | 2013 |
Pax2.1 is required for the development of thyroid follicles in zebrafish.
Topics: Animals; Disease Models, Animal; DNA-Binding Proteins; Embryo, Mammalian; Embryo, Nonmammalian; Fema | 2002 |
Influence of hyperthyroidism on rat lung cytokine production and nuclear factor-kappaB activation following ozone exposure.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemokine CCL2; Chemo | 2002 |
Experimental model for ophthalmopathy in BALB/c and outbred (CD-1) mice genetically immunized with G2s and the thyrotropin receptor.
Topics: Animals; Antibodies; Disease Models, Animal; Eye Proteins; Female; Graves Disease; Humans; Membrane | 2002 |
Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism.
Topics: Aging; Animals; Brain; Congenital Hypothyroidism; Disease Models, Animal; DNA-Binding Proteins; Fema | 2003 |
[Effect of taibai-ginseng on the mice pathology model of "kidney yindeficiency" induced by excessive throxine].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Kidney Diseases; Mice; Panax; Thyroxine; Yin | 2001 |
Effect of hypothyroidism and thyroxin replacement on growth of long bones in prenatally treated albino rats.
Topics: Animals; Bone Development; Carbimazole; Disease Models, Animal; Drug Therapy, Combination; Female; H | 2003 |
Transport of L-[125I]thyroxine by in situ perfused ovine choroid plexus: inhibition by lead exposure.
Topics: Animals; Choroid Plexus; Disease Models, Animal; Injections, Intraperitoneal; Iodine Radioisotopes; | 2003 |
A major role for non-major histocompatibility complex genes but not for microorganisms in a novel murine model of Graves' hyperthyroidism.
Topics: Adenoviridae; Animals; Antibodies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Escher | 2003 |
Dexamethasone differentially inhibits thyroxine- or growth hormone-induced body and organ growth of Snell dwarf mice.
Topics: Animals; Body Constitution; Body Weight; Dexamethasone; Disease Models, Animal; Drug Interactions; D | 2003 |
Effects of propylthiouracil and bromocryptine on serum concentrations of thyrotrophin and thyroid hormones in normal female horses.
Topics: Animals; Antithyroid Agents; Bromocriptine; Disease Models, Animal; Female; Hormone Antagonists; Hor | 2003 |
Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Animals, Newborn; Chronic Disease; Cortico | 2003 |
Calcium mobilization within hypothyroid adult rat brain synaptosomes.
Topics: Animals; Calcium; Cerebral Cortex; Disease Models, Animal; Hypothyroidism; Male; Rats; Rats, Inbred | 2003 |
Role of thyroid hormones on the synthesis and release of atrial natriuretic peptide in rats with acute renal failure.
Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Creatinine; Disease Models, Animal; Disease | 2003 |
Development of a murine model of autoimmune thyroiditis induced with homologous mouse thyroid peroxidase.
Topics: Animals; Autoantibodies; Cell Division; Disease Models, Animal; Female; Immunization; Iodide Peroxid | 2004 |
Temporal and topographic ultrastructural alterations of rat heart myofibrils caused by thyroid hormone.
Topics: Animals; Cytoplasm; Desmin; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Immunoh | 2003 |
Effect of non-steroidal aromatase inhibitor on blood plasma ovarian steroid and thyroid hormones in laying hen (Gallus domesticus).
Topics: Animals; Chickens; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Fadrozole; Female; Hormones | 2003 |
Preliminary immunohistochemical investigations of thyroid C cells in an experimental model of hyperthyroidism.
Topics: Animals; Biomarkers; Calcitonin; Disease Models, Animal; Hyperthyroidism; Immunohistochemistry; Inje | 2003 |
Modulatory effects of leptin on leydig cell function of normal and hyperleptinemic rats.
Topics: Analysis of Variance; Androstenols; Animals; Animals, Newborn; Blotting, Northern; Body Weight; Dise | 2003 |
Neonatal thyroxine treatment: changes in the number of corticotropin-releasing-factor (CRF) and neuropeptide Y (NPY) containing neurons and density of tyrosine hydroxylase positive fibers (TH) in the amygdala correlate with anxiety-related behavior of wis
Topics: Amygdala; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Cell Count; Co | 2004 |
Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism.
Topics: Animals; Blotting, Northern; Blotting, Southern; Disease Models, Animal; Female; Genetic Vectors; Ge | 2004 |
Studies on experimental iodine allergy: 1. Antigen recognition of guinea pig anti-iodine antibody.
Topics: Animals; Antibody Specificity; Antigen-Antibody Reactions; Antigens; Binding Sites, Antibody; Cross | 2004 |
Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo.
Topics: Alanine; Animals; Carbon Radioisotopes; Dipeptides; Disease Models, Animal; Dose-Response Relationsh | 2004 |
Effects of hypothyroidism induced by 6-n-propylthiouracil and its reversal by T3 on rat heart superoxide dismutase, catalase and lipid peroxidation.
Topics: Animals; Catalase; Disease Models, Animal; Hyperthyroidism; Hypothyroidism; Lipid Peroxidation; Male | 2003 |
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Autoantibodies; Binding Sites, Antibody; Cycli | 2004 |
Effects of snake venom from Saudi cobras and vipers on hormonal levels in peripheral blood.
Topics: Animals; Disease Models, Animal; Elapidae; Hormones; Hydrocortisone; Insulin; Male; Radioimmunoassay | 2004 |
Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease.
Topics: Animals; Demyelinating Autoimmune Diseases, CNS; Disease Models, Animal; Encephalomyelitis, Autoimmu | 2004 |
Effects of soybean isoflavones, probiotics, and their interactions on lipid metabolism and endocrine system in an animal model of obesity and diabetes.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, | 2004 |
Reevaluating thyrotropin receptor-induced mouse models of graves' disease and ophthalmopathy.
Topics: Adoptive Transfer; Animals; CHO Cells; Cricetinae; Disease Models, Animal; Environment; Female; Grav | 2005 |
Activity of thyroid parafollicular (C) cells in rats with hyperthyroidism--preliminary ultrastructural investigations.
Topics: Animals; Disease Models, Animal; Hyperthyroidism; Male; Rats; Rats, Wistar; Thyroid Gland; Thyroxine | 2004 |
Activity of thyroid parafollicular (C) cells in rats with hyperthyroidism--immunohistochemical investigations.
Topics: Animals; Disease Models, Animal; Hyperthyroidism; Immunohistochemistry; Male; Rats; Rats, Wistar; Th | 2004 |
Effect of thyroxine on abnormal pancreatic proteomes of the hypothyroid rdw rat.
Topics: Animals; Body Weight; Cluster Analysis; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensiona | 2005 |
Characterization of cells with proliferative activity after a brain injury.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Antigens; Astrocytes; Biomarkers; Brain; Brain | 2005 |
5'-nucleotidase activity is altered by hypo- and hyperthyroidism in platelets from adult rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bl | 2005 |
Common viral infection affects pentabrominated diphenyl ether (PBDE) distribution and metabolic and hormonal activities in mice.
Topics: Animals; Carbon Radioisotopes; Coxsackievirus Infections; Cytochrome P-450 CYP1A1; Cytochrome P-450 | 2005 |
Downregulation of parathyroid hormone receptor gene expression and osteoblastic dysfunction associated with skeletal resistance to parathyroid hormone in a rat model of renal failure with low turnover bone.
Topics: Actins; Alkaline Phosphatase; Animals; Base Sequence; Bone and Bones; Disease Models, Animal; DNA Pr | 2005 |
Relation between the hypothalamic-pituitary-thyroid (HPT) axis and the hypothalamic-pituitary-adrenal (HPA) axis during repeated stress.
Topics: Adaptation, Physiological; Agouti-Related Protein; Animals; Chronic Disease; Corticosterone; Disease | 2005 |
[Fatty-acidic content in the brain structures of hypothyroid rats of different age groups].
Topics: Aging; Animals; Brain; Disease Models, Animal; Fatty Acids; Hypothyroidism; Rats; Rats, Wistar; Thyr | 2005 |
Osteopontin gene expression in the aorta and the heart of propylthiouracil-induced hypothyroid mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Blotting, Western; Body Weight; | 2005 |
Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity.
Topics: Acidosis; Ammonium Chloride; Animals; Animals, Newborn; Antithyroid Agents; Blood Gas Analysis; Dise | 2005 |
Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density.
Topics: Animals; Capillaries; Cardiomegaly; Coronary Vessels; Disease Models, Animal; Dose-Response Relation | 2006 |
Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
Topics: Alkaline Phosphatase; Animals; Brain Chemistry; Cholesterol; Disease Models, Animal; Drug Resistance | 2006 |
Tissue-specific modulation of angiotensin-converting enzyme (ACE) in hyperthyroidism.
Topics: Animals; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Hear | 2006 |
Increased susceptibility of the lungs of hyperthyroid rats to oxidant injury: specificity of effects.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Disease Susceptibility; Dos | 2006 |
PACAP 38 as a modulator of immune and endocrine responses during LPS-induced acute inflammation in rats.
Topics: Acute Disease; Animals; Cells, Cultured; Corticosterone; Disease Models, Animal; Drug Interactions; | 2006 |
Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in l-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats.
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelins; I | 2006 |
Differential Susceptibility of BALB/c and BALB/cBy mice to Graves' hyperthyroidism.
Topics: Adenoviridae; Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Genetic | 2006 |
Hormonal change and cytokine mRNA expression in peripheral blood mononuclear cells during the development of canine autoimmune thyroiditis.
Topics: Animals; Autoantibodies; Cattle; Cell Proliferation; Cytokines; Disease Models, Animal; Dogs; Immuno | 2006 |
Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect.
Topics: Adsorption; Animals; Antithyroid Agents; Bentonite; Disease Models, Animal; Dose-Response Relationsh | 2006 |
Cardio-protective role of terazosin is possibly mediated through alteration in thyroid function.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Cholesterol, Dietary; Disease Models, Animal; | 2006 |
Ehrlich tumor as model to study artificial hyperthyroidism influence on breast cancer.
Topics: Animals; Antigens, Nuclear; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Cell Nucl | 2007 |
[Influence of propyl-thiouracil-induced hypothyroidism on rat gingival mucosa].
Topics: Animals; Antithyroid Agents; Collagen; Colorimetry; Disease Models, Animal; DNA; Gingiva; Hydroxypro | 2006 |
An improved Graves' disease model established by using in vivo electroporation exhibited long-term immunity to hyperthyroidism in BALB/c mice.
Topics: Animals; Autoantibodies; Cell Line; CHO Cells; Chronic Disease; Cricetinae; Cricetulus; Disease Mode | 2007 |
Novel two-dimensional morphometric maps and quantitative analysis reveal marked growth and structural recovery of the rat hippocampal regions from early hypothyroid retardation.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain Mapping; Computer-A | 2007 |
[Effect of hypothyroidism on glial fibrillary acid protein in the structures of the rat brain].
Topics: Aging; Animals; Brain; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hypothyroidism; Immu | 2006 |
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Body Weight; Cochlea; Congenit | 2007 |
Methimazole protects lungs during hepatic ischemia-reperfusion injury in rats: an effect not induced by hypothyroidism.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antithyroid Agents; Disease Models, Animal; Hepatic | 2007 |
Thyroxine replacement in an animal model of congenital hypothyroidism.
Topics: Age Factors; Analysis of Variance; Animals; Congenital Hypothyroidism; Critical Period, Psychologica | 2007 |
Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats.
Topics: Administration, Oral; Animals; Calcium-Binding Proteins; Cardiomegaly; Disease Models, Animal; Echoc | 2007 |
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Adenosine Deaminase Inhibit | 2007 |
Amelioration of L-thyroxine-induced hyperthyroidism by coumarin (1,2-benzopyrone) in female rats.
Topics: Animals; Antithyroid Agents; Body Weight; Catalase; Cholesterol; Coumarins; Disease Models, Animal; | 2007 |
[Proliferation, apoptosis and mammary gland histomorphometry of thyroxine-treated rats on lactation and after weaning and development of offspring].
Topics: Animals; Apoptosis; Breast Feeding; Case-Control Studies; Caspase 3; Cell Cycle Proteins; Cell Proli | 2007 |
Viral infection and PBDE exposure interact on CYP gene expression and enzyme activities in the mouse liver.
Topics: Animals; Coxsackievirus Infections; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-4 | 2007 |
Effect of high molecular weight water-soluble chitosan on the trabecular bone and thickness in ovariectomized rats.
Topics: Alkaline Phosphatase; Animals; Biomechanical Phenomena; Bone and Bones; Calcium; Calcium, Dietary; C | 2007 |
Subclinical hyperthyroidism in cats: a spontaneous model of subclinical toxic nodular goiter in humans?
Topics: Adenoma; Animals; Cat Diseases; Cats; Disease Models, Animal; Goiter, Nodular; Humans; Hyperplasia; | 2007 |
Effects of adult dysthyroidism on the morphology of hippocampal neurons.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Hippocampus; Male; Methimazole; Neurons; Rand | 2008 |
Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats.
Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Clofibrate; Disease Models, Animal; Glucuron | 2008 |
Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism.
Topics: Animals; Arterioles; Atrophy; Cardiovascular Diseases; Coronary Vessels; Disease Models, Animal; Dos | 2008 |
Effect of hyperthermia on the function of thyroid gland.
Topics: Animals; Arteries; Artifacts; Body Temperature; Disease Models, Animal; Down-Regulation; Fever; Male | 2008 |
Thyroid hormones modulate occurrence and termination of ventricular fibrillation by both long-term and acute actions.
Topics: Age Factors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 2008 |
Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfa | 2008 |
Thyroid hormones may influence cortical bone healing around titanium implants: a histometric study in rats.
Topics: Analysis of Variance; Animals; Bone Density; Bone Regeneration; Bone Remodeling; Dental Implantation | 2008 |
Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness.
Topics: Animals; Critical Illness; Disease Models, Animal; Iodide Peroxidase; Kidney; Liver; Male; Molecular | 2008 |
Involution of rat iodoprive hyperplastic goiter: effect of iodide administration on thyroid function and lysosomal properties.
Topics: Animals; Disease Models, Animal; DNA; Goiter; Iodides; Kinetics; Lysosomes; Male; Proteins; Rats; Ra | 1982 |
Some functional changes in experimentally induced cardiac overload.
Topics: Aminooxyacetic Acid; Animals; Atropine; Cardiomegaly; Disease Models, Animal; Drug Combinations; Ele | 1983 |
Reduced triiodothyronine content in liver but not pituitary of the uremic rat model: demonstration of changes compatible with thyroid hormone deficiency in liver only.
Topics: Animals; Body Weight; Disease Models, Animal; Liver; Male; Nephrectomy; Organ Size; Organ Specificit | 1984 |
Increased phospholipid methylation in the myocardium of hyperthyroid rats.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Hyperthyroidism; Male; Methylation; Microsomes; Myoca | 1980 |
Effect of pituitary hollow fiber units and thyroid supplementation on growth in the little mouse.
Topics: Animals; Body Weight; Bone and Bones; Brain; Disease Models, Animal; Dwarfism; Female; Growth Hormon | 1984 |
Effect of chronic methadone administration on neuroendocrine function in developing rats.
Topics: Age Factors; Animals; Body Weight; Corticosterone; Disease Models, Animal; Female; Growth Hormone; L | 1984 |
Nerve growth factor concentration in a congenitally hypothyroid mouse model (hyt/hyt) and its responsivity to thyroxine treatment.
Topics: Animals; Congenital Hypothyroidism; Disease Models, Animal; Hypothyroidism; Mice; Mice, Inbred Strai | 1983 |
Cerebral hypothyroidism in rats with adult-onset iodine deficiency.
Topics: Animals; Brain; Diet; Disease Models, Animal; Female; Hypothyroidism; Iodine; Liver; Pituitary Gland | 1984 |
Thyroid replacement in thyroparathyroidectomized dogs.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dogs; Female; Hypoparathyroidism; Hypothyroid | 1984 |
Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism.
Topics: Animals; Blood Urea Nitrogen; Disease Models, Animal; Glycerolphosphate Dehydrogenase; Humans; Hypot | 1980 |
Are iodine-deficient rats euthyroid?
Topics: Animals; Cell Nucleus; Disease Models, Animal; Female; Glycerolphosphate Dehydrogenase; Goiter, Ende | 1982 |
Lymphocytic thyroiditis and diabetes in the BB/W rat. A new model of autoimmune endocrinopathy.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Male; | 1981 |
Castration induces a marked reduction in the incidence of thyroid cancers.
Topics: Adenocarcinoma; Age Factors; Animals; Calcitonin; Castration; Disease Models, Animal; Female; Humans | 1982 |
Spontaneous autoimmune thyroiditis in Praomys (Mastomys) natalensis.
Topics: Aging; Animals; Autoantibodies; Autoimmune Diseases; Disease Models, Animal; Female; Male; Muridae; | 1982 |
Effect of thyroxin on the transport and metabolic functions of the small intestine in albino rats.
Topics: Animals; Biological Transport, Active; Disease Models, Animal; Hyperthyroidism; Intestine, Small; Ra | 1981 |
A hyperthyreosis model experiment in rats.
Topics: Animals; Body Temperature; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Fe | 1980 |
Production of severe iodine deficiency in sheep using a prepared low-iodine diet.
Topics: Animals; Body Weight; Diet; Disease Models, Animal; Female; Goiter; Hypothyroidism; Iodine; Sheep; T | 1980 |
Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis. Secondary role of iodination.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Cross Reactions; Disease Models, Animal; Epitopes; Fem | 1995 |
The effect of L-thyroxine on the anaemia response in Trypanosoma congolense infected rabbits.
Topics: Anemia; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hematocrit; Humans; Male; Rab | 1995 |
The role of cytokines in the lipopolysaccharide-induced sick euthyroid syndrome in mice.
Topics: Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Euthyroid Sick Syndrom | 1995 |
Hyperthyroidism increases adenosine transport and metabolism in the rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; AMP Deaminase; An | 1995 |
A simple model for studying the correction of in utero hypothyroidism in the rat.
Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Female; Fetal Diseases; | 1995 |
A histomorphometric study of bone changes in thyroid dysfunction in rats.
Topics: Analysis of Variance; Animals; Body Weight; Calcinosis; Disease Models, Animal; Drug Overdose; Hyper | 1995 |
Differential expression of alpha- and beta-thyroid hormone receptor genes in the developing rat brain under hypothyroidism.
Topics: Animals; Brain; Brain Chemistry; Densitometry; Disease Models, Animal; DNA; Female; Gene Expression | 1995 |
Vascular reactivity to vasoconstrictors in aorta and renal vasculature of hyperthyroid and hypothyroid rats.
Topics: Animals; Aorta, Thoracic; Barium Compounds; Blood Pressure; Chlorides; Disease Models, Animal; Dose- | 1994 |
Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: implications for the establishment of a mouse model for Graves' disease.
Topics: Animals; Disease Models, Animal; Female; Graves Disease; Immunoglobulin G; Iodine; Mice; Mice, Inbre | 1995 |
Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.
Topics: Animals; Cell Movement; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunoglo | 1994 |
A rat model of thyroid hormone-induced bone loss: effect of antiresorptive agents on regional bone density and osteocalcin gene expression.
Topics: Animals; Base Sequence; Bone Density; Bone Resorption; Calcitonin; Disease Models, Animal; DNA, Comp | 1994 |
Suppression of thyrotropin-releasing hormone gene expression by interleukin-1-beta in the rat: implications for nonthyroidal illness.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Gene Expression; In Situ Hybridiza | 1994 |
Flurbiprofen effects on bone resorption.
Topics: Analysis of Variance; Animals; Bone and Bones; Bone Resorption; Disease Models, Animal; Fetus; Flurb | 1993 |
Methimazole as a protectant against cisplatin-induced nephrotoxicity using the dog as a model.
Topics: Animals; Cisplatin; Disease Models, Animal; Dogs; Glutathione; Kidney; Kidney Diseases; Male; Methim | 1993 |
The effects of the aminobisphosphonate alendronate on thyroid hormone-induced osteopenia in rats.
Topics: Alendronate; Animals; Bone Diseases, Metabolic; Bone Remodeling; Bone Resorption; Diphosphonates; Di | 1993 |
Preservation of functioning human thyroid organoids in the scid mouse: 1. System characterization.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Graves Disease; Humans; Mice; Mice, SCID; Organoid | 1993 |
The influence of thyroid hormone replacement in a porcine brain death model.
Topics: Animals; Brain Death; Disease Models, Animal; Hemodynamics; Liver; Liver Transplantation; Swine; Thy | 1993 |
Initiation of cardiac hypertrophy in response to thyroxine is not limited by age.
Topics: Aging; Animals; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Heart; Hemodynamics; | 1993 |
Pituitary and serum levels of prolactin (PRL), thyroid stimulating hormone (TSH) and serum thyroxine (T4) in hereditary dwarf rats (rdw/rdw).
Topics: Animals; Disease Models, Animal; Dwarfism, Pituitary; Female; Male; Mutation; Pituitary Gland; Prola | 1993 |
Hearing loss and cochlear abnormalities in the congenital hypothyroid (hyt/hyt) mouse.
Topics: Animals; Auditory Threshold; Cochlea; Congenital Hypothyroidism; Disease Models, Animal; Evoked Pote | 1995 |
Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Disease Models, Animal; Eating; Epilep | 1996 |
Transformation and recovery of rat skeletal muscles in pathologic hormonal states.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Insulin; Male; Muscle Cont | 1995 |
Tissue-specific alterations in insulin-like growth factor-I concentrations in response to 3,3',5-triiodo-L-thyronine supplementation in the growth hormone receptor-deficient sex-linked dwarf chicken.
Topics: Adipose Tissue; Animals; Chickens; Disease Models, Animal; Dwarfism; Female; Genetic Linkage; Growth | 1997 |
Analysis of amyloid deposition in a transgenic mouse model of homozygous familial amyloidotic polyneuropathy.
Topics: Amyloid; Amyloid Neuropathies; Animals; Blood Proteins; Disease Models, Animal; Female; Homozygote; | 1997 |
Thyroid hormone metabolism in the rat brain in an animal model of 'behavioral dependence' on ethanol.
Topics: Alcoholism; Amygdala; Animals; Behavior, Animal; Catalysis; Disease Models, Animal; Frontal Lobe; Io | 1997 |
Hyperparathyroidism associated with a chronic hypothyroid state.
Topics: Adenoma; Animals; Antithyroid Agents; Calcium; Chronic Disease; Disease Models, Animal; Female; Hype | 1997 |
Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice.
Topics: Adenylyl Cyclases; Aneuploidy; Animals; Cell Cycle; Cholera Toxin; Cyclic AMP; Disease Models, Anima | 1997 |
Effects of thyrotropin-releasing hormone and its analogs on daytime sleepiness and cataplexy in canine narcolepsy.
Topics: Animals; Cataplexy; Disease Models, Animal; Dogs; Nootropic Agents; Protein Binding; Sleep Stages; S | 1997 |
Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Herni | 1997 |
Primary hormonogenic sites as conserved autoepitopes on thyroglobulin in murine autoimmune thyroiditis: role of MHC class II.
Topics: Adoptive Transfer; Amino Acid Sequence; Animals; Conserved Sequence; Disease Models, Animal; Epitope | 1997 |
Zinc supplementation on serum levels and hepatic conversion of thyroid hormones in obese (ob/ob) mice.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Iodide Peroxidase; Liver; M | 1998 |
Cold stress facilitates calcium mobilization from bone in an ovariectomized rat model of osteoporosis.
Topics: Alkaline Phosphatase; Animals; Calcium; Calcium-Transporting ATPases; Cold Temperature; Corticostero | 1998 |
Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice.
Topics: Animals; Animals, Newborn; Antithyroid Agents; Body Weight; Disease Models, Animal; Dystrophin; Hypo | 1998 |
Metabolic adaptation to experimentally increased glucose demand in ruminants.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Fatty Ac | 1998 |
Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism.
Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiomegaly; Disease Models, | 1998 |
Novel insight from transgenic mice into thyroid hormone resistance and the regulation of thyrotropin.
Topics: Animals; Disease Models, Animal; Mice; Mice, Transgenic; Mutation; Pituitary Gland; Protein Precurso | 1999 |
Effect of propylthiouracil induced hypothyroidism in developing rat cerebellum: comparison of cerebellar parameters in five day old normal and treated rat pups.
Topics: Animals; Animals, Newborn; Antithyroid Agents; Cerebellum; Disease Models, Animal; Embryonic and Fet | 1998 |
Heart hypertrophy induced by levothyroxine aggravates ischemic lesions and reperfusion arrhythmias in rats.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiomegaly; Disease Models, Animal; Female; Male | 1997 |
Evaluation and characterization of congenital hypothyroidism in rdw dwarf rats.
Topics: Animals; Blood Pressure; Body Weight; Congenital Hypothyroidism; Disease Models, Animal; Female; Gro | 1998 |
Maternal hypothyroxinemia disrupts neurotransmitter metabolic enzymes in developing brain.
Topics: Aging; Animals; Brain; Choline O-Acetyltransferase; Disease Models, Animal; Dopa Decarboxylase; Fema | 1999 |
[Role of growth hormone underproduction and support load deficit in development of muscle atrophy and osteopenia in tail-suspended rats].
Topics: Animals; Bone Diseases, Metabolic; Disease Models, Animal; Follow-Up Studies; Growth Hormone; Hindli | 1999 |
Comparison of immune responses to extracellular domains of mouse and human thyrotropin receptor.
Topics: Amino Acid Sequence; Animals; Antibodies; Disease Models, Animal; Glycoproteins; Graves Disease; Hum | 1999 |
Experimental salmonellosis in guinea-pigs: haematological and biochemical studies.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Cattle; Cattle Dise | 1999 |
Effect of exogenous thyroxine on the development of the Purkinje cell in fetal alcohol effects in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spect | 1999 |
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.
Topics: Animals; Autoantibodies; Autoimmune Diseases; CHO Cells; Cricetinae; Cricetulus; Disease Models, Ani | 2000 |
[Chronobiological characteristics of renal function under conditions of T4- and T3-hyperthyreosis].
Topics: Animals; Circadian Rhythm; Disease Models, Animal; Hyperthyroidism; Kidney; Kidney Function Tests; M | 2000 |
Effects of chronic mild stress (CMS) on thyroid hormone function in two rat strains.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chronic Disease; Disease Models, Animal | 2000 |
[Contribution of the renin-angiotensin system to blood pressure variability in hyperthyroid rats].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiomegaly; Chronic Dise | 2000 |
Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae.
Topics: Acetylcholine; Acute Disease; Animals; Aorta; Blood Pressure; Blotting, Western; Body Weight; Cardio | 2000 |
Age-related changes of protein- and RNA-synthetic processes in experimental hyper- and hypothyroidism.
Topics: Aging; Animals; Blood Proteins; Disease Models, Animal; Hyperthyroidism; Hypothyroidism; Liver; Male | 2001 |
Rapid and transient reduction in circulating thyroid hormones following systemic antigen priming: implications for functional collaboration between dendritic cells and thyroid.
Topics: Animals; Cell Movement; Chickens; Dendritic Cells; Disease Models, Animal; Euthyroid Sick Syndromes; | 2001 |
Characterization of mice deficient in the Src family nonreceptor tyrosine kinase Frk/rak.
Topics: Animals; Disease Models, Animal; Epithelium; Euthyroid Sick Syndromes; Female; Gene Expression Profi | 2002 |
Clinical and experimental studies on the pathogenesis of depression.
Topics: Adult; Animals; Brain; Depression; Disease Models, Animal; Female; Histocytochemistry; Humans; Hypot | 1977 |
Resin hemoperfusion: a method of removing circulating thyroid hormones.
Topics: Animals; Chromatography, Ion Exchange; Disease Models, Animal; Dogs; Hypothyroidism; Ion Exchange Re | 1976 |
Decrease in rat cardiac myosin ATPase with aortic constriction: prevention by thyroxine treatment.
Topics: Actomyosin; Adenosine Triphosphatases; Animals; Aorta; Body Weight; Calcium; Constriction; Disease M | 1979 |
Increased collagen synthesis and the kinetic characteristics of prolyl hydroxylase in tissues of rabbits with experimental arteriosclerosis.
Topics: Animals; Aorta; Arteriosclerosis; Collagen; Cross Reactions; Disease Models, Animal; DNA; Epinephrin | 1976 |
Suitability of the rabbit for hypothyroid studies.
Topics: Animals; Body Temperature; Disease Models, Animal; Female; Hypothyroidism; Male; Methods; Rabbits; T | 1979 |
Euthyroidism via iodide supplementation in hereditary congenital goiter with thyroglobulin deficiency.
Topics: Animals; Disease Models, Animal; Goats; Goiter; Iodides; Iodoproteins; Molecular Weight; Thyroxine; | 1978 |
A model for therapeutic interventins on established coronary atherosclerosis in a nonhuman primate.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Coronary Disease; Coronary Vessels; Diet, Atherogenic | 1976 |
Compensatory thyroid hypertrophy after hemithyroidectomy in rats.
Topics: Animals; Disease Models, Animal; DNA; Goiter; Hypertrophy; Male; Organ Size; Proteins; Rats; RNA; Th | 1976 |
[Metabolism of thyroxine in the diabetic rat].
Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Rats; Thyroxine | 1976 |
Experimental cretinism in lambs: an intrauterine model with thyroid evaluation in surviving lambs.
Topics: Amniotic Fluid; Animals; Congenital Hypothyroidism; Disease Models, Animal; Female; Fetal Diseases; | 1975 |
Failure of triiodothyronine to prevent propylthiouracil-induced hypothyroidism and goiter in fetal sheep.
Topics: Animals; Disease Models, Animal; Female; Fetal Diseases; Goiter; Hypothyroidism; Organ Size; Pregnan | 1976 |
Experimental canine atherosclerosis and its prevention. The dietary induction of severe coronary, cerebral, aortic, and iliac atherosclerosis and its prevention by safflower oil.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Cholesterol, Dietary; Coronary Disease; Diet, Atherogeni | 1976 |
The nude rat is established as a model for endocrine studies: regulation of thyroid function and xenotransplantation of a thyroid tumor cell line.
Topics: Animals; Circadian Rhythm; Disease Models, Animal; Humans; Male; Neoplasm Transplantation; Rats; Rat | 1992 |
Testosterone regulates epidermal growth factor levels in the thyroid gland of hypothyroid mice.
Topics: Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermal Growth Fac | 1992 |
Functional changes in the right and left ventricle during development of cardiac hypertrophy and after its regression.
Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; Heart Ventricles; Isoproterenol; Male; Rats | 1992 |
Central hypothyroidism.
Topics: Animals; Disease Models, Animal; Female; Humans; Hypothyroidism; Middle Aged; Rats; Thyrotropin; Thy | 1992 |
The thyroidectomized pregnant rat--an animal model to study fetal effects of maternal hypothyroidism.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Embryonic and Fetal De | 1991 |
Thyroidal iodine metabolism in obese-strain chickens before immune-mediated damage.
Topics: Animals; Autoimmunity; Autoradiography; Chickens; Disease Models, Animal; Iodine; Obesity; Thyroglob | 1991 |
[Seasonal characteristics of the effect of thyroid hormone deficiency on indolamine metabolism in the rat epiphysis].
Topics: Animals; Disease Models, Animal; Hypothyroidism; Male; Pineal Gland; Rats; Rats, Inbred Strains; Sea | 1991 |
The SCID-hu mouse and thyroid autoimmunity: characterization of human thyroid autoantibody secretion.
Topics: Animals; Autoantibodies; Bone Marrow Transplantation; Disease Models, Animal; Enzyme-Linked Immunoso | 1991 |
Thyroid hormone economy in pregnant rats near term: a "physiological" animal model of nonthyroidal illness?
Topics: Animals; Body Weight; Cerebral Cortex; Disease Models, Animal; Female; Iodide Peroxidase; Liver; Lun | 1990 |
Developmental delays associated with prenatal alcohol exposure are reversed by thyroid hormone treatment.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Disease Models, Animal; Embryonic and Fetal | 1990 |
[Subcellular basis of disorders of the contractile capacity of the heart in L-thyroxine-induced thyrotoxicosis].
Topics: Animals; Disease Models, Animal; Dogs; Heart Failure; Male; Myocardial Contraction; Myocardium; Sarc | 1990 |
Effects of melatonin and hypothyroidism on somatomedin levels of female Syrian hamsters.
Topics: Animals; Cricetinae; Darkness; Disease Models, Animal; Drug Combinations; Female; Growth Hormone; Hy | 1989 |
Induction and stability of the adult myosin phenotype in striated muscles of dwarf mice after chronic thyroid hormone treatment.
Topics: Animals; Disease Models, Animal; Dwarfism; Electrophoresis; Enzyme-Linked Immunosorbent Assay; Fluor | 1989 |
[The vitamin B1 and C content in the tissues of animals with thyrotoxicosis].
Topics: Animals; Ascorbic Acid; Disease Models, Animal; Liver; Rats; Thiamine; Thyrotoxicosis; Thyroxine; Ti | 1989 |
Insulin secretion and action in the hyperthyroid rat.
Topics: Animals; Blood Glucose; Disease Models, Animal; Glucose Tolerance Test; Hyperthyroidism; Insulin; In | 1985 |
The protective mechanism of thyroidectomy in a rat model of chronic renal failure.
Topics: Animals; Disease Models, Animal; Glomerular Filtration Rate; Hemodynamics; Isoproterenol; Kidney Fai | 1989 |
Cyclic hormonogenesis in gray collie dogs: interactions of hematopoietic and endocrine systems.
Topics: Adrenocorticotropic Hormone; Agranulocytosis; Animals; Disease Models, Animal; Dogs; Endocrine Gland | 1987 |
[Effects of yang-restoring and yin-nourishing herbs on serum TRH, T3 and T4 levels in experimental hyperthyroid and hypothyroid rats].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyperthyroidism; Hypothyroidism; Med | 1987 |
Hypotensive action of parathyroid hormone in hypoparathyroid and hyperparathyroid rats.
Topics: Animals; Blood Pressure; Calcium; Calcium Carbonate; Disease Models, Animal; Femur; Hyperparathyroid | 1988 |
An appropriate model for congenital hypothyroidism in the rat induced by neonatal treatment with propylthiouracil and surgical thyroidectomy: studies on learning ability and biochemical parameters.
Topics: Animals; Body Weight; Brain Chemistry; Conditioning, Psychological; Congenital Hypothyroidism; Disea | 1988 |
Hyperthyroxinemic mice have reduced natural killer cell activity. Evidence for a defective trigger mechanism.
Topics: Animals; Cytotoxicity Tests, Immunologic; Disease Models, Animal; Female; Graves Disease; Hypothyroi | 1987 |
The effects of postoperative factors on serum thyroid hormones and rat liver nuclear 3,5,3'-triiodothyronine receptor concentrations in surgical models of uremia and regenerating liver.
Topics: Animals; Body Weight; Cell Nucleus; Chronic Disease; Disease Models, Animal; Fasting; Hepatectomy; L | 1987 |
Low-iodine diet for the production of severe I deficiency in marmosets (Callithrix jacchus jacchus).
Topics: Animals; Body Weight; Callitrichinae; Diet; Disease Models, Animal; Female; Iodine; Male; Thyroid Gl | 1985 |
Hereditary pituitary dwarfism in mice affects skeletal and cardiac myosin isozyme transitions differently.
Topics: Aging; Animals; Animals, Newborn; Disease Models, Animal; Dwarfism, Pituitary; Electrophoresis, Poly | 1985 |
Prenatal hypothyroidism and brain composition in a primate.
Topics: Animals; Body Water; Brain; Brain Chemistry; Carbonic Anhydrases; Chlorides; Disease Models, Animal; | 1973 |
[Intravital uptake of trypan blue in the epithelial cells of the proximal renal tubule following sublimate intoxication and subsequent treatment with L-thyroxine (author's transl)].
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Epithelial Cells; Epithelium; Kidney Function | 1973 |
Increased myocardial cathepsin D activity during regression of thyrotoxic cardiac hypertrophy.
Topics: Acid Phosphatase; Animals; Body Weight; Cardiomegaly; Cathepsins; Creatine Kinase; Disease Models, A | 1974 |
Role of endocrine factors in the pathogenesis of cardiac hypertrophy.
Topics: Acromegaly; Animals; Body Weight; Cardiomegaly; Catecholamines; Disease Models, Animal; Growth Hormo | 1974 |
[Glucose tolerance and thyroid function].
Topics: Animals; Blood Glucose; Disease Models, Animal; Gluconeogenesis; Glucose Tolerance Test; Hyperthyroi | 1974 |
Increased 131I uptake by the thyroid glands of Obese strain (OS) chickens derived from non-Protamone-supplemented hens.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Caseins; Chickens; Disease Models, Animal; Iodine; Iod | 1974 |
Animal models for the study of progression and regression of atherosclerosis.
Topics: Animals; Aorta; Arteriosclerosis; Bile Acids and Salts; Cholesterol; Cholestyramine Resin; Coronary | 1972 |
The hormonal restoration of the intrinsic contractile function of the atrophic hearts of hypophysectomized rats.
Topics: Animals; Atrophy; Coronary Disease; Disease Models, Animal; Elasticity; Growth Hormone; Heart; Hypop | 1972 |
Effect of growth hormone and thyroxine on the contractile properties of dystrophic muscle.
Topics: Animals; Disease Models, Animal; DNA; Glucosyltransferases; Growth Hormone; Mice; Muscle Contraction | 1973 |
Dopamine receptor site sensitivity in hyperthyroid guinea pigs: a possible model of hyperthyroid chorea.
Topics: Animals; Apomorphine; Behavior, Animal; Chorea; Corpus Striatum; Disease Models, Animal; Dopamine; G | 1973 |
An experimental approach to the understanding and treatment of hereditary syndromes with congenital deafness and hypothyroidism.
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Cochlea; Deafness; Disease Models, Animal; Female | 1973 |
Adverse effects of excess thyroid hormone on the maturation of rat cerebrum.
Topics: Animals; Animals, Newborn; Cerebrosides; Cholesterol; Disease Models, Animal; DNA; Hyperthyroidism; | 1973 |
Transplantable thyroid tumors in the rat: development of normal-appearing thyroid follicles in the differentiated tumors, and development of differentiated tumors from iodine-deficient, thyroxine-involuted goiters.
Topics: Animals; Cell Differentiation; Diet; Disease Models, Animal; Goiter; Iodine; Iodine Isotopes; Male; | 1970 |
Triton-induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs.
Topics: Animals; Carboxylic Acids; Cholesterol; Clofibrate; Disease Models, Animal; Fasting; Hyperlipidemias | 1972 |
Studies on the pharmacological control of hyperlipemia in experimental nephrotic syndrome.
Topics: Animals; Butyrates; Chemical and Drug Induced Liver Injury; Cholesterol; Cholestyramine Resin; Disea | 1970 |
Thyroid storm treatment with blood exchange and plasmapheresis.
Topics: Adolescent; Aged; Animals; Disease Models, Animal; Exchange Transfusion, Whole Blood; Female; Humans | 1970 |
[Effect of thyroxine on the course of acute renal failure. I. Effect of L-thyroxine treatment upon the mortality of rabbits and mice with manifest acute renal failure (model of so-called mercury-nephrosis)].
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Hyperthyroidism; Male; Mercury Poisoni | 1971 |
[Effect of thyroxine on the course of acute renal failure. II. Effect of L-thyroxine administration on plasma level and kidney excretion of various substances in rabbits presenting acute kidney failure (studies using the so-called sublimate nephrosis mode
Topics: Acute Kidney Injury; Animals; Blood Glucose; Blood Proteins; Calcium; Chlorides; Cholesterol; Creati | 1971 |
[Effect of thyroxine on the course of acute kidney failure. 3. Effect of L-thyroxine administration on glomerular filtration rate, effective renal plasma flow and tubular secretory and reabsorption capacity in rabbits with toxic renal damage (Studies usin
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Creatinine; Disease Models, Animal; Female; Glome | 1971 |