Page last updated: 2024-11-06

thyroxine and Disease Exacerbation

thyroxine has been researched along with Disease Exacerbation in 116 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"NAFLD was diagnosed by ultrasound."5.51Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women. ( Bao, Y; Chen, P; Feng, L; Hou, X; Jia, W; Jiao, L; Wang, H; Wei, L; Zhong, L, 2019)
"There is a 3-fold increased risk of developing overt hypothyroidism with dietary supplementation of 16 mg soy phytoestrogens with subclinical hypothyroidism."5.15The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomized, double-blind, crossover study. ( Atkin, SL; Chapman, T; Kilpatrick, ES; Manuchehri, AM; Rigby, AS; Sathyapalan, T; Thatcher, NJ, 2011)
" Patients with overt or subclinical hypothyroidism should be treated with levothyroxine to improve their cardiovascular function and the potential risk of heart failure."5.01The Management of Thyroid Abnormalities in Chronic Heart Failure. ( Biondi, B, 2019)
"Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) affects up to 10% of the adult population."5.01Subclinical Hypothyroidism: A Review. ( Biondi, B; Cappola, AR; Cooper, DS, 2019)
"Reports published with the following search terms were searched:, thyroid, hypothyroidism, hyperthyroidism, subclinical hyperthyroidism, subclinical hypothyroidism, levothyroxine, triiodothyronine, antithyroid drugs, radioiodine, deiodinases, clinical symptoms, heart rate, HF, systolic function, diastolic function, systemic vascular resistance, endothelial function, amiodarone and atrial fibrillation."4.88Mechanisms in endocrinology: Heart failure and thyroid dysfunction. ( Biondi, B, 2012)
"Subclinical hypothyroidism is defined as normal serum free thyroxine and tri-iodothyronine concentrations and a slightly eleveted serum thyrotropin (TSH) concentration."4.82[Subclinical hypothyroidism]. ( Corvilain, B; Heureux, M, 2004)
"In the management of elevated thyroid-stimulating hormone levels during pregnancy, the frequency of adrenal insufficiency suspecting hypothyroidism may be higher than expected; therefore, we must be careful about starting levothyroxine replacement therapy for hypothyroidism."4.31Clinical insights of pregnancy management, adrenal insufficiency as a possible cause of elevated TSH: a pilot study of case series. ( Inaba, T; Kanazawa, K; Koga, S; Kuwabara, K, 2023)
"Of the 200 patients included in the study, 19% developed clinical hypothyroidism (TSH > 10 µIU/mL, or required initiation of or dose increase in levothyroxine)."4.12Outcomes and Management of Immune Checkpoint Inhibitor-Induced Hypothyroidism: A Retrospective Analysis. ( Phillips, AL; Reeves, DJ, 2022)
" With current dosing schemes, the vast majority of patients develop permanent post-RAI hypothyroidism and are placed on life-long levothyroxine therapy."3.83Transient Hypothyroidism after Radioiodine for Graves' Disease: Challenges in Interpreting Thyroid Function Tests. ( Doi, SA; Sheehan, MT, 2016)
"Subclinical hypothyroidism (SCH) is defined as a raised serum thyroid stimulating hormone level with normal thyroxine."3.83Management of Patients with Subclinical Hypothyroidism in Primary Care. ( Kearney, PM; McCarthy, E; Russell, A, 2016)
"We measured thyrotropin (TSH) and free thyroxine (T4) levels at baseline examinations performed from 2000 to 2003 in the cohort of Japanese atomic-bomb survivors and identified 71 patients with spontaneous subclinical hypothyroidism (normal free T4 and TSH >4."3.77Risk for progression to overt hypothyroidism in an elderly Japanese population with subclinical hypothyroidism. ( Akahoshi, M; Ando, T; Ashizawa, K; Hida, A; Horie, I; Ichimaru, S; Imaizumi, M; Maeda, R; Nagataki, S; Nakashima, E; Sera, N; Soda, M; Tominaga, T; Ueki, I; Usa, T, 2011)
" The parameters assessed were periodontitis-related bone loss, quality of tooth-supporting alveolar bone and the number of cells positive for tartrate-resistant acid phosphatase (TRAP), a marker of bone resorption."3.75The influence of thyroid hormones on periodontitis-related bone loss and tooth-supporting alveolar bone: a histological study in rats. ( Casati, MZ; de Toledo, S; Feitosa, DS; Marques, MR; Nociti, FH; Sallum, EA, 2009)
"3% required replacement therapy with levothyroxine (L-T4) because of progression to overt hypothyroidism or persistence of serum TSH >10 mIU/L, and 52."3.75Natural history of mild subclinical hypothyroidism: prognostic value of ultrasound. ( Bessa, B; Purisch, S; Rosário, PW; Valadão, MM, 2009)
"Patients who presented with goiter and autoimmune thyroiditis were grouped as those with euthyroidism, subclinical hypothyroidism, and overt hypothyroidism on the basis of levels of thyroxine and thyrotropin at presentation."3.74Goitrous autoimmune thyroiditis in a pediatric population: a longitudinal study. ( Ambardar, VK; Chhillar, M; Chugh, PK; Gopalakrishnan, S; Sahoo, M; Sankar, R, 2008)
"To examine the natural history of a subnormal serum thyroid-stimulating hormone (TSH) concentration with normal concentrations of both serum free thyroxine (FT4) and free triiodothyronine (FT3) (subclinical hyperthyroidism)."3.73Observations concerning the natural history of subclinical hyperthyroidism. ( Woeber, KA, 2005)
"Differentiated thyroid cancer is the most common malignant carcinoma in female population."2.58[Advances in postoperative thyroid-stimulating hormone suppression therapy in females with thyroid cancer]. ( Song, F; Yi, HL, 2018)
"Primary therapy of thyroid cancer is an adequate surgery: total thyreoidectomy and, if necessary, lymph node dissection or limited surgery in selected cases."2.47[Differentiated thyroid cancer -- 2009]. ( Konrády, A, 2011)
"Treatment of metastatic differentiated thyroid cancer is first based on the use of radioiodine and thyrotropin-suppressive thyroid hormone treatment."2.45Clinical trials for progressive differentiated thyroid cancer: patient selection, study design, and recent advances. ( Schlumberger, M; Sherman, SI, 2009)
"Hypothyroidism is a common disease that is often undiagnosed or misdiagnosed because the signs and symptoms are often confused with other conditions."2.44Evaluating and treating the patient with hypothyroid disease. ( Hennessey, JV; Scherger, JE, 2007)
"Subclinical hypothyroidism is also associated with the risk of progression to overt hypothyroidism and with the risk of neuropsychiatric effects."2.44[Subclinical hypothyroidism]. ( Krysiak, R; Marek, B; Okopień, B, 2008)
"To investigate the association between disease progression and subclinical hypothyroidism, a Cox regression analyses was performed in 379 patients with MCI."1.72Subclinical Hypothyroidism and Cognitive Impairment. ( Kim, S; Park, YH; Pyun, JM, 2022)
"Papillary thyroid cancer (80% of thyroid cancer) whose incidence is increasing worldwide, is associated with Hashimoto's thyroiditis."1.51A model of the cost of delaying treatment of Hashimotos thyroiditis: thyroid cancer initiation and growth. ( Merrill, SJ; Pandiyan, B, 2019)
"NAFLD was diagnosed by ultrasound."1.51Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women. ( Bao, Y; Chen, P; Feng, L; Hou, X; Jia, W; Jiao, L; Wang, H; Wei, L; Zhong, L, 2019)
"Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes."1.46Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017)
"Whether D3 induction occurs in dilated cardiomyopathy is unknown."1.46Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy. ( Dorfman, DM; Huang, SA; Jay, PY; Jugo, RH; Maynard, MA; Padera, RF; Wassner, AJ; Zavacki, AM, 2017)
"Age-related cognitive decline has been associated with changes in endogenous hormones and epigenetic modification of chromatin, including histone acetylation."1.43Accelerated reduction of serum thyroxine and hippocampal histone acetylation links to exacerbation of spatial memory impairment in aged CD-1 mice pubertally exposed to bisphenol-a. ( Cao, L; Chen, GH; Ge, H; Jiang, W; Li, XW; Wang, F; Wu, PC, 2016)
"Among the 28 NT, 15 NT progressed to septic shock, with 5 NT group A and 10 NT in group B."1.42Nonthyroidal illnesses syndrome in full-term newborns with sepsis. ( Araujo, MC; Carvalho, WB; Ceccon, ME; Diniz, EM; Silva, MH, 2015)
"By medical replacement treatment, clinical hypothyroidism (CI) related hypercholesterolemia decreased significantly in 28%."1.40[Relationship between hypothyroidism and cholesterol out of the records of 1756 patients]. ( Campanella, N; Catozzo, V; Ferretti, M; Morosini, P; Sampaolo, G; Vichi, G, 2014)
"Progression of slipped capital femoral epiphysis following in situ screw fixation typically occurs through loosening of the screw in the metaphysis."1.39Bilateral epiphyseal migration following fixation for slipped capital femoral epiphyses in a hypothyroid child. ( Holroyd, B; Jeffery, RS; Walter, RP, 2013)
"The development of Graves' disease (GD) from Hashimoto's thyroiditis (HT) has sporadically been reported, but no data are available concerning the prevalence of this sequence of events in GD patients."1.36Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease. ( Arrigo, T; Corrias, A; De Luca, F; Lombardo, F; Mussa, A; Salerno, M; Vigone, MC; Wasniewska, M, 2010)
"Pregnancy does not cause thyroid cancer recurrence in PTC survivors who have no structural or biochemical evidence of disease persistence at the time of conception."1.36Impact of pregnancy on outcome and prognosis of survivors of papillary thyroid cancer. ( Benbassat, C; Grozinski-Glasberg, S; Hirsch, D; Levy, S; Lifshitz, A; Shimon, I; Shraga-Slutzky, I; Singer, J; Tsvetov, G; Weinstein, R, 2010)
"Nonautoimmune primary hyperthyroidism was diagnosed, and brain magnetic resonance imaging and computed tomography showed also Arnold-Chiari malformation type I."1.36Hyperthyroidism caused by a germline activating mutation of the thyrotropin receptor gene: difficulties in diagnosis and therapy. ( Bertalan, R; Kovács, B; Lotz, G; Patócs, A; Rácz, K; Sallai, A; Sólyom, J; Szabó, E; Szabó, I, 2010)
"We present 4 patients with Graves' disease who developed spontaneous hypothyroidism during follow-up."1.35[Spontaneous hypothyroidism in 4 patients with Graves-Basedow disease]. ( Aznar Ondoño, I; Del Monte Jarabo Bueno, M; González-González, A; Recio Cordova, JM, 2009)
"In a mouse model of autoimmune Graves' disease, stimulatory anti-TSH receptor (TSHR) antibodies (TSAbs) slowly evolve upon repeated immunization with TSHR and lead to hyperthyroidism."1.34Diversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses. ( Dorevitch, S; Gangi, E; Gupta, S; Lefranc, MP; Martinez, O; Mordi, D; Prabhakar, BS, 2007)
"The thyroid nodule was preoperatively evaluated with blood chemistry, ultrasound, nuclear scanning and FNAC."1.33Clinical importance of solitary solid nodule of the thyroid in endemic goiter region. ( Aslaner, A; Coskun, O; Gurleyik, E, 2005)
"In women with type 2 diabetes without known thyroid disease, subclinical hypothyroidism is a common but incidental finding."1.33Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study. ( Chubb, SA; Davis, TM; Davis, WA; Inman, Z, 2005)
"Radioiodine was administered twice to deliver a total radiation dose of 70 mCi iodine (I)-131."1.32Unsuccessful radioiodine treatment of a non-toxic goiter: a case report. ( Blichert-Toft, M; Buhl, T; Feldt-Rasmussen, U; Friis, E; Hartoft-Nielsen, ML; Hesse, B; Rasmussen, AK, 2004)
"Although long-standing untreated hypopituitarism was present, there was normal physical and professional activity."1.32Long-term follow-up of childhood-onset hypopituitarism in patients with the PROP-1 gene mutation. ( Dörr, HG; Hahn, EG; Hensen, J; Pavel, ME; Pfäffle, R, 2003)
"Subtotal thyroidectomy gave the lowest recurrence rate (p = 0."1.30Ultrasonographic surveillance after surgery for euthyroid goitre in patients treated or not with thyroxine. ( Bastagli, A; Galimberti, A; Piraneo, S; Salvaggio, A; Vitri, P, 1997)
"Angiographic coronary artery disease progression may be prevented by adequate thyroid replacement in hypothyroidism."1.30The effect of thyroid hormone therapy on angiographic coronary artery disease progression. ( O'Neill, BJ; Perk, M, 1997)
" injection) were examined following chronic administration of 0."1.29Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors. ( Hayashi, Y; Kitaura, K; Mitsumori, K; Onodera, H; Shimo, T; Takahashi, M; Yasuhara, K, 1995)
"Thyrotoxicosis was treated with propylthiouracil."1.29Significant reversal of thyrotoxicosis-associated dilated cardiomyopathy with induction of the euthyroid state. ( Hamilton, EC; Wilson, BE, 1996)

Research

Studies (116)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (7.76)18.2507
2000's42 (36.21)29.6817
2010's56 (48.28)24.3611
2020's9 (7.76)2.80

Authors

AuthorsStudies
Tang, S1
Yang, M1
Zhang, D1
Tong, YJ1
Xin, Y1
Phillips, AL1
Reeves, DJ1
Pyun, JM1
Park, YH1
Kim, S1
Jonklaas, J1
Kanazawa, K1
Inaba, T1
Koga, S1
Kuwabara, K1
Pandiyan, B1
Merrill, SJ1
Doknic, M1
Gasic, V1
Stojanovic, M1
Pavlovic, S1
Marinkovic, S1
Miljic, D1
Pekic, S1
Manojlovic-Gacic, E1
Damjanovic, D1
Soldatovic, I1
Petakov, M1
Pace, C1
Tumino, D1
Russo, M1
Le Moli, R1
Naselli, A1
Borzì, G1
Malandrino, P1
Frasca, F1
Tso, M1
Nosib, S1
Devalraju, KP1
Tripathi, D1
Neela, VSK1
Paidipally, P1
Radhakrishnan, RK1
Singh, KP1
Ansari, MS1
Jaeger, M1
Netea-Maier, RT1
Netea, MG1
Park, S1
Cheng, SY2
Valluri, VL1
Vankayalapati, R1
Wassner, AJ1
Jugo, RH1
Dorfman, DM1
Padera, RF1
Maynard, MA1
Zavacki, AM1
Jay, PY1
Huang, SA1
Peeters, RP1
Iñiguez-Ariza, NM1
Stan, MN1
Bible, KC1
Ates, I1
Arikan, MF1
Altay, M1
Yilmaz, FM1
Yilmaz, N1
Berker, D1
Guler, S1
Song, F1
Yi, HL1
Biondi, B5
Cooper, DS3
Bielecka-Dabrowa, A1
Godoy, B1
Suzuki, T1
Banach, M1
von Haehling, S1
Chen, P1
Hou, X1
Wei, L1
Feng, L1
Zhong, L1
Jiao, L1
Wang, H1
Bao, Y1
Jia, W1
Scavone, M1
Carboni, E1
Stefanelli, E1
Romano, G1
Vero, A1
Giancotti, L1
Miniero, R1
Talarico, V1
Jeong, SH1
Hong, HS1
Lee, JY1
van Iersel, L1
Xu, J1
Potter, BS1
Conklin, HM1
Zhang, H1
Chemaitilly, W1
van Santen, HM1
Merchant, TE1
Cappola, AR1
Walter, RP1
Jeffery, RS1
Holroyd, B1
Cabezón, CA1
Carrizo, LC1
Costanzo, PR1
Sampaolo, G1
Campanella, N1
Catozzo, V1
Ferretti, M1
Vichi, G1
Morosini, P1
Lee, HS2
Hwang, JS1
Aversa, T4
Valenzise, M3
Corrias, A5
Salerno, M5
De Luca, F5
Mussa, A4
Rezzuto, M1
Lombardo, F2
Wasniewska, M5
Kaykhaei, MA1
Heidari, Z1
Mehrazin, A1
Rosário, PW3
Carvalho, M1
Calsolari, MR1
Messina, MF1
Capalbo, D2
Park, HJ1
Kim, J1
Han, EJ1
Park, SE1
Park, CY1
Lee, WY1
Oh, KW1
Park, SW1
Rhee, EJ1
Sharma, S1
Dabla, PK1
Kumar, M1
Silva, MH1
Araujo, MC1
Diniz, EM1
Ceccon, ME1
Carvalho, WB1
Brondfield, S1
Feingold, KR1
Shen, J1
Wang, S1
Zhao, X1
Shao, X1
Jiang, X1
Dai, Y1
Xu, S1
Pan, X1
Sheehan, MT1
Doi, SA1
McCarthy, E1
Russell, A1
Kearney, PM1
Vita, R1
Lapa, D1
Trimarchi, F1
Vita, G1
Fallahi, P1
Antonelli, A1
Benvenga, S1
Tessaris, D1
Di Mase, R1
Corica, D1
Jiang, W1
Cao, L1
Wang, F1
Ge, H1
Wu, PC1
Li, XW1
Chen, GH1
Matos, DM1
Ramalho, RJ1
Carvalho, BM1
Almeida, MA1
Passos, LF1
Vasconcelos, TT1
Melo, EV1
Oliveira, CR1
Santos, EG1
Resende, KF1
Aguiar-Oliveira, MH1
Amouzegar, A1
Ghaemmaghami, Z1
Beigy, M1
Gharibzadeh, S1
Mehran, L1
Tohidi, M1
Azizi, F1
Askari, A1
Ehrampoush, E1
Homayounfar, R1
Bahramali, E1
Farjam, M1
Hennessey, JV1
Scherger, JE1
Gopalakrishnan, S1
Chugh, PK1
Chhillar, M1
Ambardar, VK1
Sahoo, M1
Sankar, R1
Strieder, TG1
Tijssen, JG1
Wenzel, BE1
Endert, E1
Wiersinga, WM1
Lee, CY1
Hsu, HH1
Lai, HY1
Lee, ST1
Krysiak, R1
Marek, B1
Okopień, B1
Feitosa, DS1
Marques, MR1
Casati, MZ1
Sallum, EA1
Nociti, FH1
de Toledo, S1
Iacoviello, M1
Guida, P1
Guastamacchia, E1
Triggiani, V1
Forleo, C1
Catanzaro, R1
Cicala, M1
Basile, M1
Sorrentino, S1
Favale, S1
Bessa, B1
Valadão, MM1
Purisch, S1
Cassio, A1
Zirilli, G1
Bal, M1
Frick, LR1
Rapanelli, M1
Bussmann, UA1
Klecha, AJ1
Arcos, ML1
Genaro, AM1
Cremaschi, GA1
Vaurs-Barrière, C1
Deville, M1
Sarret, C1
Giraud, G1
Des Portes, V1
Prats-Viñas, JM1
De Michele, G1
Dan, B1
Brady, AF1
Boespflug-Tanguy, O1
Touraine, R1
Díez, JJ1
Iglesias, P1
González-González, A1
Recio Cordova, JM1
Aznar Ondoño, I1
Del Monte Jarabo Bueno, M1
Bałdys-Waligórska, A1
Stefańska, A1
Gołkowski, F1
Sokołowski, G1
Hubalewska-Dydejczyk, A1
Schlumberger, M1
Sherman, SI1
Voll, R1
Li, Y1
Nishihara, E1
Hirokawa, M1
Taniguchi, E1
Miyauchi, A2
Kakudo, K1
Lu, C1
Zhao, L1
Ying, H1
Willingham, MC1
Bertalan, R1
Sallai, A1
Sólyom, J1
Lotz, G1
Szabó, I1
Kovács, B1
Szabó, E1
Patócs, A1
Rácz, K1
Jain, G1
Devpura, G1
Gupta, BS1
Arrigo, T1
Vigone, MC1
Hirsch, D1
Levy, S1
Tsvetov, G1
Weinstein, R1
Lifshitz, A1
Singer, J1
Shraga-Slutzky, I1
Grozinski-Glasberg, S1
Shimon, I1
Benbassat, C1
Vadiveloo, T1
Donnan, PT1
Cochrane, L1
Leese, GP1
Pantalone, KM1
Nasr, C1
Konrády, A1
Sathyapalan, T1
Manuchehri, AM1
Thatcher, NJ1
Rigby, AS1
Chapman, T1
Kilpatrick, ES1
Atkin, SL1
Imaizumi, M1
Sera, N1
Ueki, I1
Horie, I1
Ando, T1
Usa, T1
Ichimaru, S1
Nakashima, E1
Hida, A1
Soda, M1
Tominaga, T1
Ashizawa, K1
Maeda, R1
Nagataki, S1
Akahoshi, M1
Özen, S1
Berk, Ö1
Şimşek, DG1
Darcan, S1
Faria, CD1
Ribeiro, S1
Kochi, C1
Silva, AP1
Ribeiro, BN1
Marçal, LT1
Santos, FH1
Eduardo, CP1
Monte, O1
Longui, CA1
Yang, JW1
Han, ST1
Song, SH1
Kim, MK1
Kim, JS1
Choi, SO1
Han, BG1
Monzani, A1
Prodam, F1
Rapa, A1
Moia, S1
Agarla, V1
Bellone, S1
Bona, G1
Carlé, A1
Bülow Pedersen, I1
Knudsen, N1
Perrild, H1
Ovesen, L1
Rasmussen, LB1
Jørgensen, T1
Laurberg, P1
Kasatkina, SG1
Panova, TN1
Shin, DH1
Lee, MJ1
Oh, HJ1
Ko, KI1
Kim, CH1
Doh, FM1
Koo, HM1
Kim, HR1
Han, JH1
Park, JT1
Han, SH1
Yoo, TH1
Kang, SW1
Pirnat, E1
Fidler, V1
Zaletel, K1
Gaberscek, S1
Hojker, S1
Rodríguez, E1
García, AM1
Foyo, E1
Amato, D1
Paniagua, R1
Pavel, ME1
Hensen, J1
Pfäffle, R1
Hahn, EG1
Dörr, HG1
Telkova, IL2
Tepliakov, AT2
Heureux, M1
Corvilain, B1
Hartoft-Nielsen, ML1
Rasmussen, AK1
Friis, E1
Blichert-Toft, M1
Buhl, T1
Hesse, B1
Feldt-Rasmussen, U1
Blackwell, J1
Piccoli, GB1
Mezza, E1
Burdese, M1
Terzolo, M1
Grassi, G1
Bermond, F1
Soragna, G1
Gai, M1
Dani, F1
Jeantet, A1
Segoloni, GP1
Piccoli, G1
Soroushyari, A1
Do, D1
Langton, J1
Hershman, JM1
Chubb, SA1
Davis, WA1
Inman, Z1
Davis, TM1
Woeber, KA1
Gurleyik, E1
Coskun, O1
Aslaner, A1
Pace, L1
Klain, M1
Albanese, C1
Salvatore, B1
Storto, G1
Soricelli, A1
Salvatore, M1
Nielsen, VE1
Bonnema, SJ1
Boel-Jørgensen, H1
Grupe, P1
Hegedüs, L1
Martinez, O1
Gangi, E1
Mordi, D1
Gupta, S1
Dorevitch, S1
Lefranc, MP1
Prabhakar, BS1
Mardaleishvili, KG1
Nemsadze, GG1
Metreveli, DS1
Roinishvili, TL1
Witzke, O1
Wiemann, J1
Patschan, D1
Wu, K1
Philipp, T1
Saller, B1
Mann, K1
Reinhardt, W1
Ferguson, DC1
Caffall, Z1
Hoenig, M1
de Jong, FJ1
Masaki, K1
Chen, H1
Remaley, AT1
Breteler, MM1
Petrovitch, H1
White, LR1
Launer, LJ1
Fiore, E1
Giustarini, E1
Mammoli, C1
Fragomeni, F1
Campani, D1
Muller, I1
Pinchera, A1
Giani, C1
Takamura, Y1
Ito, Y1
Miya, A1
Kobayashi, K1
Matsuzuka, F1
Amino, N1
Toyoda, N1
Nomura, E1
Nishikawa, M1
David, E1
Rosen, IB1
Bain, J1
James, J1
Kirsh, JC1
Mitsumori, K1
Onodera, H1
Takahashi, M2
Shimo, T1
Yasuhara, K1
Kitaura, K1
Hayashi, Y1
Wilson, BE1
Hamilton, EC1
Piraneo, S1
Vitri, P1
Galimberti, A1
Salvaggio, A1
Bastagli, A1
Perk, M1
O'Neill, BJ1
Cho, JY1
Sagartz, JE1
Capen, CC1
Mazzaferri, EL1
Jhiang, SM1
Stockigt, JR1
Huber, G1
Guglielmetti, M1
Huber, P1
Kunz, M1
Roth, CB1
Staub, JJ1
Nakae, T1
Kawanaka, M1
Suehiro, M1
Sugita, M1
Fukuchi, M1
Almeida, MR1
Alves, IL1
Terazaki, H1
Ando, Y1
Saraiva, MJ1
Franzese, A1
Buono, P1
Mascolo, M1
Leo, AL1
Valerio, G1
Chantelau, E1
Al-Abadi, AC1
Karpov, RS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Desiccated Thyroid Extract Compared to Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-blind, Crossover Study.[NCT01739972]180 participants (Anticipated)Interventional2012-05-31Recruiting
Pretreatment With Recombinant Human Thyrotropin (rhTSH) for the Effect on Thyroid Size and Function, and for the Effect of Radioiodine Treatment in Patients With Nodular Goiter. Prospective, Randomized Double-blinded Trials.[NCT00145366]Phase 2110 participants Interventional2002-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for thyroxine and Disease Exacerbation

ArticleYear
Restoration of euthyroidism with levothyroxine: implications of etiology of hypothyroidism and the degree of residual endogenous thyroid function.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Biomarkers; Disease Progression; Humans; Hypothyroidism; Quality of Life; Thyroid Hormones; Thyroxin

2022
Subclinical Hypothyroidism.
    The New England journal of medicine, 2017, 06-29, Volume: 376, Issue:26

    Topics: Aged; Algorithms; Disease Progression; Female; Humans; Hypothyroidism; Practice Guidelines as Topic;

2017
[Advances in postoperative thyroid-stimulating hormone suppression therapy in females with thyroid cancer].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2018, May-07, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Disease Progression; Female; Humans; Hypothyroidism; Neoplasm Recurrence, Local; Pos

2018
Subclinical Hyperthyroidism.
    The New England journal of medicine, 2018, Jun-21, Volume: 378, Issue:25

    Topics: Aged; Antithyroid Agents; Disease Progression; Female; Humans; Hyperthyroidism; Iodine Radioisotopes

2018
Subclinical hypothyroidism and the development of heart failure: an overview of risk and effects on cardiac function.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2019, Volume: 108, Issue:3

    Topics: Disease Progression; Global Health; Heart Failure, Diastolic; Heart Ventricles; Humans; Hypothyroidi

2019
The Management of Thyroid Abnormalities in Chronic Heart Failure.
    Heart failure clinics, 2019, Volume: 15, Issue:3

    Topics: Disease Management; Disease Progression; Heart Failure; Hormone Replacement Therapy; Humans; Thyroid

2019
Subclinical Hypothyroidism: A Review.
    JAMA, 2019, Jul-09, Volume: 322, Issue:2

    Topics: Age Factors; Disease Progression; Female; Hashimoto Disease; Hormone Replacement Therapy; Humans; Hy

2019
Skull metastasis from follicular thyroid carcinoma: report of three cases and review of literature.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:11

    Topics: Adenocarcinoma, Follicular; Aged; Biomarkers, Tumor; Biopsy; Cranial Irradiation; Craniotomy; Diseas

2015
Evaluating and treating the patient with hypothyroid disease.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Adult; Algorithms; Cardiovascular Diseases; Clinical Protocols; Comorbidity; Disease Progression; Dr

2007
[Subclinical hypothyroidism].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2008, Volume: 61, Issue:4-6

    Topics: Atherosclerosis; Cardiovascular Diseases; Comorbidity; Disease Progression; Humans; Hypothyroidism;

2008
Clinical trials for progressive differentiated thyroid cancer: patient selection, study design, and recent advances.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:12

    Topics: Bone Neoplasms; Carcinoma, Papillary; Clinical Trials as Topic; Disease Progression; Humans; Iodine

2009
[Undetected Hashimoto encephalopathy--a diagnostic challenge in child psychiatry and child neurology].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2010, Volume: 38, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Brain Damage, Chronic; Child; Cognition

2010
Approach to a low TSH level: patience is a virtue.
    Cleveland Clinic journal of medicine, 2010, Volume: 77, Issue:11

    Topics: Adult; Chorionic Gonadotropin; Disease Progression; Euthyroid Sick Syndromes; Female; Humans; Hypert

2010
[Differentiated thyroid cancer -- 2009].
    Orvosi hetilap, 2011, Jan-30, Volume: 152, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Carcinoma; Carcinoma, Medullary

2011
Subclinical thyroid disease.
    Lancet (London, England), 2012, Mar-24, Volume: 379, Issue:9821

    Topics: Atrial Fibrillation; Cardiovascular Diseases; Comorbidity; Diagnosis, Differential; Disease Progress

2012
Mechanisms in endocrinology: Heart failure and thyroid dysfunction.
    European journal of endocrinology, 2012, Volume: 167, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease;

2012
Endocrine disorders in childhood and adolescence. Natural history of subclinical hypothyroidism in children and adolescents and potential effects of replacement therapy: a review.
    European journal of endocrinology, 2013, Volume: 168, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Disease Progression; Female; Hormone Replacement Therapy; Human

2013
[Subclinical hypothyroidism].
    Revue medicale de Bruxelles, 2004, Volume: 25, Issue:3

    Topics: Biomarkers; Disease Progression; Humans; Hypothyroidism; Thyrotropin; Thyroxine; Triiodothyronine

2004
Subclinical thyrotoxicosis.
    Postgraduate medical journal, 2001, Volume: 77, Issue:903

    Topics: Cardiovascular Diseases; Diagnosis, Differential; Disease Progression; Humans; Hyperthyroidism; Oste

2001

Trials

4 trials available for thyroxine and Disease Exacerbation

ArticleYear
[Evaluation of radioiodine 131I treatment in Graves' disease patients with mild orbitopathy].
    Przeglad lekarski, 2009, Volume: 66, Issue:4

    Topics: Antibodies; Combined Modality Therapy; Disease Progression; Graves Disease; Humans; Iodine Radioisot

2009
The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomized, double-blind, crossover study.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:5

    Topics: Adult; Aged; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cross-Over Studies; Dietar

2011
Early change of thyroid hormone concentration after 131I treatment in patients with solitary toxic adenoma.
    Nuklearmedizin. Nuclear medicine, 2002, Volume: 41, Issue:4

    Topics: Adenoma; Adult; Aged; Disease Progression; Female; Humans; Interleukin-6; Iodine Radioisotopes; Male

2002
Stimulation with 0.3-mg recombinant human thyrotropin prior to iodine 131 therapy to improve the size reduction of benign nontoxic nodular goiter: a prospective randomized double-blind trial.
    Archives of internal medicine, 2006, Jul-24, Volume: 166, Issue:14

    Topics: Adult; Aged; Antithyroid Agents; Disease Progression; Dose-Response Relationship, Drug; Double-Blind

2006

Other Studies

93 other studies available for thyroxine and Disease Exacerbation

ArticleYear
Clinical Characteristics and Follow-Up of 19 Children With Hashimoto's Thyroiditis Aged Below 3 Years: A Single-Center Retrospective Analysis.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Child, Preschool; Disease Progression; Female; Follow-Up Studies; Hashimoto Disease; Humans; Hypothy

2021
Outcomes and Management of Immune Checkpoint Inhibitor-Induced Hypothyroidism: A Retrospective Analysis.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:10

    Topics: Adult; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Hypothyroidism;

2022
Subclinical Hypothyroidism and Cognitive Impairment.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 88, Issue:2

    Topics: Aged; Cognitive Dysfunction; Disease Progression; Humans; Hypothyroidism; Middle Aged; Thyroid Disea

2022
Clinical insights of pregnancy management, adrenal insufficiency as a possible cause of elevated TSH: a pilot study of case series.
    BMC pregnancy and childbirth, 2023, Oct-04, Volume: 23, Issue:1

    Topics: Adrenal Insufficiency; Disease Progression; Female; Humans; Hypothyroidism; Pilot Projects; Pregnanc

2023
A model of the cost of delaying treatment of Hashimotos thyroiditis: thyroid cancer initiation and growth.
    Mathematical biosciences and engineering : MBE, 2019, 09-05, Volume: 16, Issue:6

    Topics: Biopsy, Fine-Needle; Computer Simulation; Disease Progression; Hashimoto Disease; Humans; Hypothalam

2019
Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the effects of growth hormone replacement introduction in middle adulthood.
    Pituitary, 2020, Volume: 23, Issue:4

    Topics: Absorptiometry, Photon; Adult; Body Composition; Bone Density; Bone Diseases, Metabolic; Brain Neopl

2020
Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Adult; Autoantibodies; Disease Progression; Drug Therapy, Combination; Female; Hashimoto Disease; Hu

2020
Typical and reverse Takotsubo syndromes as initial manifestations of consecutive Addisonian crises in a 38-year-old patient: the heart has its reasons!
    BMJ case reports, 2021, Jan-28, Volume: 14, Issue:1

    Topics: Addison Disease; Adult; Disease Progression; Echocardiography; Female; Humans; Hydrocortisone; Hypot

2021
Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk.
    JCI insight, 2021, 07-08, Volume: 6, Issue:13

    Topics: Adolescent; Adult; Animals; Antigens, Bacterial; Bacterial Proteins; Disease Progression; Disease Tr

2021
Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy.
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:5

    Topics: Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Disease Progression; Iodide Peroxidase; Mi

2017
Effect of thyroid hormone suppression on control of advanced well-differentiated thyroid cancer.
    Endocrine, 2018, Volume: 59, Issue:1

    Topics: Aged; Carcinoma, Papillary; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; R

2018
The effect of oxidative stress on the progression of Hashimoto's thyroiditis.
    Archives of physiology and biochemistry, 2018, Volume: 124, Issue:4

    Topics: Adult; Algorithms; Asymptomatic Diseases; Biomarkers; Disease Progression; Female; Follow-Up Studies

2018
Free triiodothyronine is associated with the occurrence and remission of nonalcoholic fatty liver disease in euthyroid women.
    European journal of clinical investigation, 2019, Volume: 49, Issue:4

    Topics: Alanine Transaminase; Cross-Sectional Studies; Disease Progression; Female; Humans; Liver Cirrhosis,

2019
Prediction of Transient or Permanent Congenital Hypothyroidism from Initial Thyroid Stimulating Hormone Levels.
    Indian pediatrics, 2018, Dec-15, Volume: 55, Issue:12

    Topics: Biomarkers; Child, Preschool; Congenital Hypothyroidism; Decision Support Techniques; Disease Progre

2018
The association between thyroid echogenicity and thyroid function in pediatric and adolescent Hashimoto's thyroiditis.
    Medicine, 2019, Volume: 98, Issue:14

    Topics: Adolescent; Child; Child, Preschool; Disease Progression; Female; Hashimoto Disease; Humans; Male; R

2019
Clinical Importance of Free Thyroxine Concentration Decline After Radiotherapy for Pediatric and Adolescent Brain Tumors.
    The Journal of clinical endocrinology and metabolism, 2019, 11-01, Volume: 104, Issue:11

    Topics: Adolescent; Aging; Body Height; Brain Neoplasms; Child; Child, Preschool; Cohort Studies; Disease Pr

2019
Bilateral epiphyseal migration following fixation for slipped capital femoral epiphyses in a hypothyroid child.
    Acta orthopaedica Belgica, 2013, Volume: 79, Issue:2

    Topics: Adolescent; Bone Screws; Disease Progression; Epiphyses; Femur Neck; Humans; Hypothyroidism; Male; P

2013
Evolution of differentiated thyroid cancer during pregnancy in a community University Hospital in Buenos Aires, Argentina.
    Arquivos brasileiros de endocrinologia e metabologia, 2013, Volume: 57, Issue:4

    Topics: Adult; Argentina; Carcinoma, Papillary; Disease Progression; Female; Follow-Up Studies; Humans; Iodi

2013
[Relationship between hypothyroidism and cholesterol out of the records of 1756 patients].
    Recenti progressi in medicina, 2014, Volume: 105, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholesterol; Disease Progressio

2014
The natural course of Hashimoto's thyroiditis in children and adolescents.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:9-10

    Topics: Adolescent; Child; Disease Progression; Female; Hashimoto Disease; Humans; Hypothyroidism; Male; Ret

2014
Underlying Hashimoto's thyroiditis negatively affects the evolution of subclinical hypothyroidism in children irrespective of other concomitant risk factors.
    Thyroid : official journal of the American Thyroid Association, 2015, Volume: 25, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Disease Progression; Female; Hashimoto Disease; Humans; Hypothy

2015
Large thyroid cyst in a patient with congenital hypothyroidism.
    Arquivos brasileiros de endocrinologia e metabologia, 2014, Volume: 58, Issue:9

    Topics: Biopsy, Fine-Needle; Congenital Hypothyroidism; Cysts; Disease Progression; Goiter, Nodular; Humans;

2014
Natural history of subclinical hypothyroidism with TSH ≤10 mIU/l: a prospective study.
    Clinical endocrinology, 2016, Volume: 84, Issue:6

    Topics: Adult; Aged; Brazil; Disease Progression; Follow-Up Studies; Humans; Hypothyroidism; Middle Aged; Pr

2016
Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology.
    European journal of endocrinology, 2015, Volume: 173, Issue:6

    Topics: Adolescent; Asymptomatic Diseases; Autoantibodies; Case-Control Studies; Child; Child, Preschool; Di

2015
Association of low baseline free thyroxin levels with progression of coronary artery calcification over 4 years in euthyroid subjects: the Kangbuk Samsung Health Study.
    Clinical endocrinology, 2016, Volume: 84, Issue:6

    Topics: Adult; Aged; Coronary Artery Disease; Disease Progression; Euthyroid Sick Syndromes; Female; Humans;

2016
Evaluation of Thyroid Hormone Status in Children with Steroid Resistant Nephrotic Syndrome: A North India Study.
    Endocrine, metabolic & immune disorders drug targets, 2015, Volume: 15, Issue:4

    Topics: Asymptomatic Diseases; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Disease Progres

2015
Nonthyroidal illnesses syndrome in full-term newborns with sepsis.
    Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:6

    Topics: Disease Progression; Euthyroid Sick Syndromes; Humans; Infant; Infant, Newborn; Sepsis; Shock, Septi

2015
Symptomatic Graves' Disease After Autoimmune Hypothyroidism.
    The American journal of medicine, 2016, Volume: 129, Issue:5

    Topics: Adult; Disease Progression; Fatigue; Graves Disease; Hashimoto Disease; Heart Rate; Humans; Immunogl

2016
Transient Hypothyroidism after Radioiodine for Graves' Disease: Challenges in Interpreting Thyroid Function Tests.
    Clinical medicine & research, 2016, Volume: 14, Issue:1

    Topics: Adult; Disease Progression; Female; Graves Disease; Humans; Hypothyroidism; Iodine Radioisotopes; Ma

2016
Management of Patients with Subclinical Hypothyroidism in Primary Care.
    Irish medical journal, 2016, Volume: 109, Issue:1

    Topics: Aged; Cohort Studies; Disease Management; Disease Progression; Female; Humans; Hypothyroidism; Irela

2016
Certain HLA alleles are associated with stress-triggered Graves' disease and influence its course.
    Endocrine, 2017, Volume: 55, Issue:1

    Topics: Age of Onset; Alleles; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Genetic Assoc

2017
Five-Year Prospective Evaluation of Thyroid Function Test Evolution in Children with Hashimoto's Thyroiditis Presenting with Either Euthyroidism or Subclinical Hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:10

    Topics: Adolescent; Asymptomatic Diseases; Child; Child, Preschool; Cohort Studies; Disease Progression; Fem

2016
Accelerated reduction of serum thyroxine and hippocampal histone acetylation links to exacerbation of spatial memory impairment in aged CD-1 mice pubertally exposed to bisphenol-a.
    Age (Dordrecht, Netherlands), 2016, Volume: 38, Issue:5-6

    Topics: Acetylation; Aging; Animals; Behavior Rating Scale; Benzhydryl Compounds; Cognitive Dysfunction; Dis

2016
Evolution to permanent or transient conditions in children with positive neonatal TSH screening tests in Sergipe, Brazil.
    Archives of endocrinology and metabolism, 2016, Volume: 60, Issue:5

    Topics: Brazil; Congenital Hypothyroidism; Disease Progression; Female; Follow-Up Studies; Humans; Incidence

2016
Natural Course of Euthyroidism and Clues for Early Diagnosis of Thyroid Dysfunction: Tehran Thyroid Study.
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:5

    Topics: Adult; Autoantibodies; Disease Progression; Early Diagnosis; Female; Follow-Up Studies; Humans; Inci

2017
Serum insulin in pathogenesis and treatment of osteoarthritis.
    Medical hypotheses, 2017, Volume: 99

    Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression;

2017
Goitrous autoimmune thyroiditis in a pediatric population: a longitudinal study.
    Pediatrics, 2008, Volume: 122, Issue:3

    Topics: Adolescent; Autoantibodies; Biopsy, Fine-Needle; Child; Disease Progression; Female; Follow-Up Studi

2008
Prediction of progression to overt hypothyroidism or hyperthyroidism in female relatives of patients with autoimmune thyroid disease using the Thyroid Events Amsterdam (THEA) score.
    Archives of internal medicine, 2008, Aug-11, Volume: 168, Issue:15

    Topics: Adult; Antibodies; Disease Progression; Family; Female; Graves Disease; Hashimoto Disease; Humans; H

2008
Rapid progression of hypothyroidism-related pituitary hyperplasia.
    Journal of neurosurgery. Pediatrics, 2008, Volume: 2, Issue:3

    Topics: Adenoma; Child; Diagnosis, Differential; Disease Progression; Female; Humans; Hyperplasia; Hypothyro

2008
The influence of thyroid hormones on periodontitis-related bone loss and tooth-supporting alveolar bone: a histological study in rats.
    Journal of periodontal research, 2009, Volume: 44, Issue:4

    Topics: Acid Phosphatase; Alveolar Bone Loss; Alveolar Process; Animals; Biomarkers; Bone Density; Disease P

2009
Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients.
    Current pharmaceutical design, 2008, Volume: 14, Issue:26

    Topics: Aged; Chronic Disease; Disease Progression; Echocardiography; Electrocardiography; Female; Follow-Up

2008
Natural history of mild subclinical hypothyroidism: prognostic value of ultrasound.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:1

    Topics: Adult; Antibodies, Anti-Idiotypic; Autoantigens; Disease Progression; Female; Humans; Hypothyroidism

2009
Prospective evaluation of the natural course of idiopathic subclinical hypothyroidism in childhood and adolescence.
    European journal of endocrinology, 2009, Volume: 160, Issue:3

    Topics: Adolescent; Body Height; Body Mass Index; Child; Child, Preschool; Disease Progression; Female; Foll

2009
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
    Biological psychiatry, 2009, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres

2009
Pelizaeus-Merzbacher-Like disease presentation of MCT8 mutated male subjects.
    Annals of neurology, 2009, Volume: 65, Issue:1

    Topics: Brain; Child; Disease Progression; DNA Mutational Analysis; Exons; Family Health; Follow-Up Studies;

2009
An analysis of the natural course of subclinical hyperthyroidism.
    The American journal of the medical sciences, 2009, Volume: 337, Issue:4

    Topics: Aged; Disease Progression; Female; Humans; Hyperthyroidism; Kaplan-Meier Estimate; Male; Middle Aged

2009
[Spontaneous hypothyroidism in 4 patients with Graves-Basedow disease].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:5

    Topics: Adult; Aged; Autoantibodies; Disease Progression; Female; Goiter; Graves Disease; Humans; Hypothyroi

2009
Distinct clinical, serological, and sonographic characteristics of hashimoto's thyroiditis based with and without IgG4-positive plasma cells.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Adult; Aged; Autoantibodies; Disease Progression; Female; Fibrosis; Hashimoto Disease; Humans; Immun

2010
Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma.
    Endocrinology, 2010, Volume: 151, Issue:4

    Topics: Adenocarcinoma, Follicular; Animals; Blotting, Western; Cell Proliferation; Disease Models, Animal;

2010
Hyperthyroidism caused by a germline activating mutation of the thyrotropin receptor gene: difficulties in diagnosis and therapy.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:3

    Topics: Adolescent; Arnold-Chiari Malformation; Child; Disease Progression; Genome; Germ-Line Mutation; Huma

2010
Abnormalities in the thyroid function tests as surrogate marker of advancing HIV infection in infected adults.
    The Journal of the Association of Physicians of India, 2009, Volume: 57

    Topics: Adult; Biomarkers; CD4 Lymphocyte Count; Disease Progression; Epidemiologic Methods; Female; HIV Inf

2009
Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease.
    Hormone research in paediatrics, 2010, Volume: 73, Issue:6

    Topics: Adolescent; Autoantibodies; Child; Disease Progression; Female; Graves Disease; Hashimoto Disease; H

2010
Natural history of subclinical hyperthyroidism in elderly patients with TSH between 0.1 and 0.4 mIU/l: a prospective study.
    Clinical endocrinology, 2010, Volume: 72, Issue:5

    Topics: Aged; Disease Progression; Female; Follow-Up Studies; Humans; Hyperthyroidism; Middle Aged; Predicti

2010
Impact of pregnancy on outcome and prognosis of survivors of papillary thyroid cancer.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:10

    Topics: Adenocarcinoma, Papillary; Adult; Disease Progression; Female; Follow-Up Studies; Humans; Neoplasm R

2010
The Thyroid Epidemiology, Audit, and Research Study (TEARS): the natural history of endogenous subclinical hyperthyroidism.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Databases, Factual; Disease Progression; Female; Humans;

2011
Risk for progression to overt hypothyroidism in an elderly Japanese population with subclinical hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:11

    Topics: Aged; Aged, 80 and over; Asian People; Autoantibodies; Cohort Studies; Disease Progression; Female;

2011
Clinical course of Hashimoto's thyroiditis and effects of levothyroxine therapy on the clinical course of the disease in children and adolescents.
    Journal of clinical research in pediatric endocrinology, 2011, Volume: 3, Issue:4

    Topics: Adolescent; Autoantibodies; Child; Child, Preschool; Disease Progression; Female; Follow-Up Studies;

2011
TSH neurosecretory dysfunction (TSH-nd) in Down syndrome (DS): low risk of progression to Hashimoto's thyroiditis.
    Arquivos brasileiros de endocrinologia e metabologia, 2011, Volume: 55, Issue:8

    Topics: Anthropometry; Autoantibodies; Child, Preschool; Disease Progression; Down Syndrome; Female; Follow-

2011
Serum T3 level can predict cardiovascular events and all-cause mortality rates in CKD patients with proteinuria.
    Renal failure, 2012, Volume: 34, Issue:3

    Topics: Biomarkers; Cardiovascular Diseases; Cause of Death; Disease Progression; Female; Follow-Up Studies;

2012
Graves' hyperthyroidism and moderate alcohol consumption: evidence for disease prevention.
    Clinical endocrinology, 2013, Volume: 79, Issue:1

    Topics: Adult; Alcohol Drinking; Anti-Infective Agents, Local; Case-Control Studies; Denmark; Disease Progre

2013
[Impact of replacement therapy for subclinical hypothyroidism on cardiovascular risk markers in patients with type 2 diabetes mellitus].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:11

    Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; Cholesterol; Diabetes Mellitus, Type 2; Dis

2012
Thyroid hormone replacement therapy attenuates the decline of renal function in chronic kidney disease patients with subclinical hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:6

    Topics: Aged; Disease Progression; Down-Regulation; Female; Follow-Up Studies; Glomerular Filtration Rate; H

2013
Role of thyroid hormones on the synthesis and release of atrial natriuretic peptide in rats with acute renal failure.
    Nephron. Experimental nephrology, 2003, Volume: 95, Issue:1

    Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Creatinine; Disease Models, Animal; Disease

2003
Long-term follow-up of childhood-onset hypopituitarism in patients with the PROP-1 gene mutation.
    Hormone research, 2003, Volume: 60, Issue:4

    Topics: Adolescent; Age of Onset; Body Height; Bone Density; Child; Disease Progression; Follow-Up Studies;

2003
[Changes of thyroid hormone levels in the progression of coronary arteriosclerosis].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:4

    Topics: Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Disease Progression; Heart Fail

2004
Unsuccessful radioiodine treatment of a non-toxic goiter: a case report.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:2

    Topics: Denmark; Disease Progression; Drug Administration Schedule; Female; Goiter, Nodular; Humans; Iodine;

2004
Evaluation and treatment of hyperthyroidism and hypothyroidism.
    Journal of the American Academy of Nurse Practitioners, 2004, Volume: 16, Issue:10

    Topics: Antithyroid Agents; Disease Progression; Drug Interactions; Hormone Replacement Therapy; Humans; Hyp

2004
Progression of renal failure without proteinuria in a patient with type 1 diabetes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:12

    Topics: Adult; Biopsy; Creatine Kinase; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progressi

2004
Partial withdrawal of levothyroxine to stimulate serum thyroglobulin for thyroid cancer monitoring.
    Thyroid : official journal of the American Thyroid Association, 2004, Volume: 14, Issue:12

    Topics: Adult; Aged; Disease Progression; Female; Humans; Male; Middle Aged; Recombinant Proteins; Thyroglob

2004
Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study.
    Clinical endocrinology, 2005, Volume: 62, Issue:4

    Topics: Adult; Autoantibodies; Biomarkers; Blood Glucose; Cholesterol; Cholesterol, HDL; Cross-Sectional Stu

2005
Observations concerning the natural history of subclinical hyperthyroidism.
    Thyroid : official journal of the American Thyroid Association, 2005, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Disease Progression; Female; Follow-Up Studies; Goiter, Nodular; Gra

2005
Clinical importance of solitary solid nodule of the thyroid in endemic goiter region.
    Indian journal of medical sciences, 2005, Volume: 59, Issue:9

    Topics: Adult; Aged; Biomarkers; Biopsy, Fine-Needle; Diagnosis, Differential; Disease Progression; Female;

2005
Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:2

    Topics: Adenocarcinoma, Follicular; Adult; Aged; Aged, 80 and over; Disease Progression; Female; Humans; Iod

2006
Diversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses.
    Endocrinology, 2007, Volume: 148, Issue:2

    Topics: Animals; Autoantibodies; Cell Line; Complementarity Determining Regions; Disease Progression; Genes,

2007
[About correlation of dysfunction of the thyroid gland with fibrocystic diseases in women].
    Georgian medical news, 2006, Issue:140

    Topics: Adult; Biomarkers; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Fibrocystic Breas

2006
Differential T4 degradation pathways in young patients with preterminal and terminal renal failure.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2007, Volume: 39, Issue:5

    Topics: Acute Kidney Injury; Adult; Cohort Studies; Diet; Disease Progression; Female; Humans; Iodine; Kidne

2007
Obesity increases free thyroxine proportionally to nonesterified fatty acid concentrations in adult neutered female cats.
    The Journal of endocrinology, 2007, Volume: 194, Issue:2

    Topics: Animals; Cats; Diabetes Mellitus, Type 2; Disease Progression; Fatty Acids, Nonesterified; Female; I

2007
Thyroid function, the risk of dementia and neuropathologic changes: the Honolulu-Asia aging study.
    Neurobiology of aging, 2009, Volume: 30, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Asian; Brain; Cohort Studies; Comorbidity; Disease Progr

2009
Favorable predictive value of thyroid autoimmunity in high aggressive breast cancer.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:9

    Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Autoimmunity; Breast Neoplasms; Carcinoma, Ductal; Disease

2007
3,5,3'-Triiodothyronine thyrotoxicosis due to increased conversion of administered levothyroxine in patients with massive metastatic follicular thyroid carcinoma.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:6

    Topics: Adenocarcinoma, Follicular; Adult; Aged; Aged, 80 and over; Disease Progression; Female; Humans; Iod

2008
Management of the hot thyroid nodule.
    American journal of surgery, 1995, Volume: 170, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma; D

1995
Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors.
    Cancer letters, 1995, Jun-08, Volume: 92, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Disease Progression; Goiter; Hyperplasia; Male; Nitrosamines; O

1995
Significant reversal of thyrotoxicosis-associated dilated cardiomyopathy with induction of the euthyroid state.
    Journal of endocrinological investigation, 1996, Volume: 19, Issue:1

    Topics: Adult; Antithyroid Agents; Body Weight; Cardiomyopathy, Dilated; Disease Progression; Echocardiograp

1996
Ultrasonographic surveillance after surgery for euthyroid goitre in patients treated or not with thyroxine.
    The European journal of surgery = Acta chirurgica, 1997, Volume: 163, Issue:1

    Topics: Adult; Aged; Disease Progression; Female; Goiter; Humans; Male; Middle Aged; Recurrence; Retrospecti

1997
The effect of thyroid hormone therapy on angiographic coronary artery disease progression.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:3

    Topics: Aged; Coronary Disease; Disease Progression; Drug Administration Schedule; Female; Humans; Hypothyro

1997
Early cellular abnormalities induced by RET/PTC1 oncogene in thyroid-targeted transgenic mice.
    Oncogene, 1999, Jun-17, Volume: 18, Issue:24

    Topics: Age of Onset; Animals; Carrier Proteins; Cell Division; Congenital Hypothyroidism; Disease Progressi

1999
Who should be screened for thyroid dysfunction?
    The Medical journal of Australia, 1999, Aug-02, Volume: 171, Issue:3

    Topics: Age Factors; Disease Progression; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypothyro

1999
[Functional dynamics of impending overt hypothyroidism: spontaneous evolution in patients in the years before the beginning of treatment].
    Schweizerische medizinische Wochenschrift, 1999, Dec-04, Volume: 129, Issue:48

    Topics: Analysis of Variance; Biomarkers; Disease Progression; Female; Humans; Hypothyroidism; Thyrotropin;

1999
Plummer's disease with spontaneous progression to hypothyroidism.
    Annals of nuclear medicine, 1999, Volume: 13, Issue:6

    Topics: Autoantibodies; Disease Progression; Female; Goiter, Nodular; Humans; Hypothyroidism; Middle Aged; R

1999
Comparative studies of two transthyretin variants with protective effects on familial amyloidotic polyneuropathy: TTR R104H and TTR T119M.
    Biochemical and biophysical research communications, 2000, Apr-21, Volume: 270, Issue:3

    Topics: Amino Acid Substitution; Amyloid Neuropathies; Disease Progression; Genetic Variation; Heterozygote;

2000
Thyroid autoimmunity starting during the course of type 1 diabetes denotes a subgroup of children with more severe diabetes.
    Diabetes care, 2000, Volume: 23, Issue:8

    Topics: Adolescent; Autoantibodies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Disease Progression;

2000
Possible activation of auto-immune thyroiditis from continuous subcutaneous infusion of genapol-containing insulin.
    Diabetes & metabolism, 2000, Volume: 26, Issue:4

    Topics: Autoantibodies; Chemistry, Pharmaceutical; Diabetes Mellitus, Type 1; Disease Progression; Female; H

2000
[Coronary insufficiency and metabolic hormone ratio in patients with myocardial infarction in the course of a long prospective study].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:12

    Topics: Adult; Coronary Artery Disease; Disease Progression; Female; Glucose Tolerance Test; Humans; Hydroco

2000