thyroxine has been researched along with Diabetic Glomerulosclerosis in 11 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study oxidative stress status of early type 2 diabetic nephropathy (DN) patients with subclinical hypothyroidism (SCH) and to assess effect of L-thyroxine therapy on the oxidative stress in these patients." | 9.27 | The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study. ( Chen, Y; Wu, G; Xu, M, 2018) |
| "To investigate the effect of levothyroxine (LT4) therapy on urinary albumin excretion rate (UAER) in early type 2 diabetic nephropathy (DN) and subclinical hypothyroidism (SCH) patients with mildly increased thyroid stimulating hormone (TSH) levels and serum thyroid peroxidase antibody (TPO-Ab) positivity." | 9.20 | Can levothyroxine treatment reduce urinary albumin excretion rate in patients with early type 2 diabetic nephropathy and subclinical hypothyroidism? A randomized double-blind and placebo-controlled study. ( Chen, X; Chen, Y; Liu, P; Liu, R; Wang, D; Wang, Y; Zhang, F, 2015) |
| "The progressive renal failure of a 49-year-old female diabetic patient with renal insufficiency and hypothyroidism was successfully prevented by levothyroxine sodium treatment." | 8.78 | Prevention of progressive renal failure by levothyroxine sodium in a diabetic patient with renal insufficiency and hypothyroidism. ( Miura, M; Nomoto, Y; Sakai, H, 1992) |
| "To study oxidative stress status of early type 2 diabetic nephropathy (DN) patients with subclinical hypothyroidism (SCH) and to assess effect of L-thyroxine therapy on the oxidative stress in these patients." | 5.27 | The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study. ( Chen, Y; Wu, G; Xu, M, 2018) |
| "To investigate the effect of levothyroxine (LT4) therapy on urinary albumin excretion rate (UAER) in early type 2 diabetic nephropathy (DN) and subclinical hypothyroidism (SCH) patients with mildly increased thyroid stimulating hormone (TSH) levels and serum thyroid peroxidase antibody (TPO-Ab) positivity." | 5.20 | Can levothyroxine treatment reduce urinary albumin excretion rate in patients with early type 2 diabetic nephropathy and subclinical hypothyroidism? A randomized double-blind and placebo-controlled study. ( Chen, X; Chen, Y; Liu, P; Liu, R; Wang, D; Wang, Y; Zhang, F, 2015) |
| "The progressive renal failure of a 49-year-old female diabetic patient with renal insufficiency and hypothyroidism was successfully prevented by levothyroxine sodium treatment." | 4.78 | Prevention of progressive renal failure by levothyroxine sodium in a diabetic patient with renal insufficiency and hypothyroidism. ( Miura, M; Nomoto, Y; Sakai, H, 1992) |
| "CV = cardiovascular DMN = diabetic nephropathy eGFR = estimated glomerular filtration rate fT4 = free thyroxine HbA1c = glycosylated hemoglobin HR = hazard ratio hs-CRP = high-sensitivity C-reactive protein LDL-C = low-density lipoprotein cholesterol SCH = subclinical hypothyroidism T2DM = type 2 diabetes THRT = thyroid hormone replacement therapy TSH = thyroid-stimulating hormone." | 3.88 | THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM. ( Cha, MU; Han, SH; Jhee, JH; Kang, SW; Kee, YK; Kim, H; Kim, S; Lee, M; Park, JT; Park, S; Seo, C; Yoo, TH; Yun, HR, 2018) |
| "Diabetic nephropathy was diagnosed based on abnormal 24-h urinary albumin or protein measurements (24-h urinary albumin ≥30 mg/day or 24-h urinary protein ≥150 mg/day)." | 1.46 | Subclinical hypothyroidism and diabetic nephropathy in Iranian patients with type 2 diabetes. ( Hazrati, E; Heidari, Z; Mansournia, MA; Mansournia, N; Riahi, M; Riyahi, S; Tofangchiha, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 2 |
| Wu, G | 1 |
| Xu, M | 1 |
| Seo, C | 1 |
| Kim, S | 1 |
| Lee, M | 1 |
| Cha, MU | 1 |
| Kim, H | 1 |
| Park, S | 1 |
| Yun, HR | 1 |
| Jhee, JH | 1 |
| Kee, YK | 1 |
| Han, SH | 1 |
| Yoo, TH | 1 |
| Kang, SW | 1 |
| Park, JT | 1 |
| Han, Q | 1 |
| Zhang, J | 1 |
| Wang, Y | 2 |
| Li, H | 1 |
| Zhang, R | 1 |
| Guo, R | 1 |
| Li, L | 1 |
| Teng, G | 1 |
| Wang, J | 1 |
| Wang, T | 1 |
| Liu, F | 1 |
| Liu, P | 1 |
| Liu, R | 1 |
| Chen, X | 1 |
| Wang, D | 1 |
| Zhang, F | 1 |
| Aziz, KM | 1 |
| Mansournia, N | 1 |
| Riyahi, S | 1 |
| Tofangchiha, S | 1 |
| Mansournia, MA | 1 |
| Riahi, M | 1 |
| Heidari, Z | 1 |
| Hazrati, E | 1 |
| Piccoli, GB | 1 |
| Mezza, E | 1 |
| Burdese, M | 1 |
| Terzolo, M | 1 |
| Grassi, G | 1 |
| Bermond, F | 1 |
| Soragna, G | 1 |
| Gai, M | 1 |
| Dani, F | 1 |
| Jeantet, A | 1 |
| Segoloni, GP | 1 |
| Piccoli, G | 1 |
| Chen, HS | 1 |
| Wu, TE | 1 |
| Jap, TS | 1 |
| Lu, RA | 1 |
| Wang, ML | 1 |
| Chen, RL | 1 |
| Lin, HD | 1 |
| Evers, J | 1 |
| Scheid, H | 1 |
| Miura, M | 1 |
| Nomoto, Y | 1 |
| Sakai, H | 1 |
| Vakov, L | 1 |
| Zakharieva, B | 1 |
1 review available for thyroxine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Prevention of progressive renal failure by levothyroxine sodium in a diabetic patient with renal insufficiency and hypothyroidism.
Topics: Diabetic Nephropathies; Female; Humans; Hypothyroidism; Kidney Failure, Chronic; Middle Aged; Thyrox | 1992 |
2 trials available for thyroxine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Albuminuria; Creatinine; Deoxyguanosine; Diabetes Mellitus, Type | 2018 |
Can levothyroxine treatment reduce urinary albumin excretion rate in patients with early type 2 diabetic nephropathy and subclinical hypothyroidism? A randomized double-blind and placebo-controlled study.
Topics: Adult; Albumins; Autoantibodies; Cholesterol; Cholesterol, LDL; Diabetic Nephropathies; Double-Blind | 2015 |
8 other studies available for thyroxine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM.
Topics: Aged; Asymptomatic Diseases; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathi | 2018 |
Thyroid hormones and diabetic nephropathy: An essential relationship to recognize.
Topics: Adult; Aged; Biomarkers; Biopsy; Creatinine; Diabetic Nephropathies; Female; Glomerular Filtration R | 2019 |
Association of Hypothyroidism with Body Mass Index, Systolic Blood Pressure and Proteinuria in Diabetic Patients: Does treated Hypothyroidism with Thyroxine Replacement Therapy Prevent Nephropathy/Chronic Renal Disease?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Di | 2016 |
Subclinical hypothyroidism and diabetic nephropathy in Iranian patients with type 2 diabetes.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypothyr | 2017 |
Progression of renal failure without proteinuria in a patient with type 1 diabetes.
Topics: Adult; Biopsy; Creatine Kinase; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progressi | 2004 |
Subclinical hypothyroidism is a risk factor for nephropathy and cardiovascular diseases in Type 2 diabetic patients.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; D | 2007 |
Low serum TSH levels and negative TRH test in dialysis patients.
Topics: Aged; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Goiter, Nodular; Humans; Kidney Fai | 1995 |
[Basal blood level of thyroxine in diabetes mellitus patients].
Topics: Adult; Aged; Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; D | 1987 |