thyroxine has been researched along with Diabetes Mellitus, Adult-Onset in 117 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Excerpt | Relevance | Reference |
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"To study oxidative stress status of early type 2 diabetic nephropathy (DN) patients with subclinical hypothyroidism (SCH) and to assess effect of L-thyroxine therapy on the oxidative stress in these patients." | 9.27 | The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study. ( Chen, Y; Wu, G; Xu, M, 2018) |
" Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 9.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
"The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 8.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
"Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
"Thyroxine metabolism is an important topic of pathogenesis research and treatment schedule of subclinical hypothyroidism (SCH)." | 7.96 | Relation of Gut Microbes and L-Thyroxine Through Altered Thyroxine Metabolism in Subclinical Hypothyroidism Subjects. ( Bo, T; Chen, W; Fu, Y; Gao, L; Gong, Y; Guo, T; Wang, Q; Yao, Z; Zhao, J; Zhao, M, 2020) |
"The study focuses on the levels of prolactin, cortisol, free thyroxine (fT4) and thyroid-stimulating hormone (TSH) as markers of Metabolic Syndrome (MS) which is a risk factor for Coronary Artery Disease (CAD) and type 2 Diabetes Mellitus (DM)." | 7.91 | PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS. ( Chmyr, N; Dutka, R; Leontieva, Z; Svitlyk, H, 2019) |
"We demonstrated positive associations of thyroid hormones with prevalent and incident type 2 diabetes mellitus suggesting that hyperthyroxinemia may contribute to the pathogenesis of this condition." | 7.88 | Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark. ( Dörr, M; Ittermann, T; Jørgensen, T; Markus, MRP; Schipf, S; Thuesen, BH; Völzke, H, 2018) |
"The study included three age-, sex- and weight-matched groups of amiodarone-treated patients with type 2 diabetes: patients with treated overt hypothyroidism (group I, n=15), patients with untreated subclinical hypothyroidism (group II, n=15), and subjects without thyroid disorders (group III, n=18)." | 7.83 | The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and amiodarone-induced hypothyroidism. ( Gilowska, M; Krysiak, R; Okopień, B; Szkróbka, W, 2016) |
"To evaluate the frequency with which hypothyroidism is associated with Type 2 diabetes, to examine gender and ethnic group differences, and to assess the possible impact of metformin therapy." | 7.80 | Type 2 diabetes mellitus and hypothyroidism: the possible influence of metformin therapy. ( Distiller, LA; Joffe, BI; Polakow, ES, 2014) |
"Prolonged hypoglycemia induced by acetohexamide (AH) in a patient with noninsulin dependent diabetes mellitus accompanied by primary hypothyroidism was presented." | 7.68 | A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide. ( Shibutani, Y; Yokota, T, 1991) |
"To study oxidative stress status of early type 2 diabetic nephropathy (DN) patients with subclinical hypothyroidism (SCH) and to assess effect of L-thyroxine therapy on the oxidative stress in these patients." | 5.27 | The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study. ( Chen, Y; Wu, G; Xu, M, 2018) |
" Studies assessed hypothyroidism (6 studies), hyperthyroidism (5 studies), thyrotropin (TSH) in the reference range (4 studies), and free thyroxine (FT4) in the reference range (3 studies) in relation to incident type 2 diabetes." | 5.22 | Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes. ( Chaker, L; Ikram, MA; Ittermann, T; Ligthart, S; Peeters, R; Roa Dueñas, OH; Van der Burgh, AC, 2022) |
"Metformin administration influences TSH without change of FT4 in patients with type 2 diabetes and concomitant hypothyroidism." | 5.14 | TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients. ( Agabiti-Rosei, E; Agosti, B; Cappelli, C; Castellano, M; Chiovato, L; Cimino, A; De Martino, E; Gandossi, E; Pirola, I; Rotondi, M; Valentini, U, 2009) |
" Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 5.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
" During pregnancy, mildly elevated maternal free thyroxine levels less than 20% above the upper limit may not be harmful to unaffected fetuses." | 4.98 | Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature. ( Guan, H; Guo, H; Guo, R; Li, Y; Shan, Z; Wu, D, 2018) |
"The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 4.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
"Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
"Thyroxine metabolism is an important topic of pathogenesis research and treatment schedule of subclinical hypothyroidism (SCH)." | 3.96 | Relation of Gut Microbes and L-Thyroxine Through Altered Thyroxine Metabolism in Subclinical Hypothyroidism Subjects. ( Bo, T; Chen, W; Fu, Y; Gao, L; Gong, Y; Guo, T; Wang, Q; Yao, Z; Zhao, J; Zhao, M, 2020) |
"The study focuses on the levels of prolactin, cortisol, free thyroxine (fT4) and thyroid-stimulating hormone (TSH) as markers of Metabolic Syndrome (MS) which is a risk factor for Coronary Artery Disease (CAD) and type 2 Diabetes Mellitus (DM)." | 3.91 | PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS. ( Chmyr, N; Dutka, R; Leontieva, Z; Svitlyk, H, 2019) |
"Treatment of hypothyroidism involves the endogenous conversion of thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and may not be optimal in some cases when based on T4 alone." | 3.91 | Cognitive function in hypothyroidism: what is that deiodinase again? ( Hernandez, A, 2019) |
"We demonstrated positive associations of thyroid hormones with prevalent and incident type 2 diabetes mellitus suggesting that hyperthyroxinemia may contribute to the pathogenesis of this condition." | 3.88 | Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark. ( Dörr, M; Ittermann, T; Jørgensen, T; Markus, MRP; Schipf, S; Thuesen, BH; Völzke, H, 2018) |
"CV = cardiovascular DMN = diabetic nephropathy eGFR = estimated glomerular filtration rate fT4 = free thyroxine HbA1c = glycosylated hemoglobin HR = hazard ratio hs-CRP = high-sensitivity C-reactive protein LDL-C = low-density lipoprotein cholesterol SCH = subclinical hypothyroidism T2DM = type 2 diabetes THRT = thyroid hormone replacement therapy TSH = thyroid-stimulating hormone." | 3.88 | THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM. ( Cha, MU; Han, SH; Jhee, JH; Kang, SW; Kee, YK; Kim, H; Kim, S; Lee, M; Park, JT; Park, S; Seo, C; Yoo, TH; Yun, HR, 2018) |
"Increasing evidence suggests an association between thyroid-stimulating hormone (TSH), free thyroxine (fT4), and deiodinases with insulin resistance and type 2 diabetes mellitus (T2D)." | 3.85 | Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study. ( Bos, MM; Noordam, R; Smit, RAJ; Trompet, S; van Heemst, D, 2017) |
"The study included three age-, sex- and weight-matched groups of amiodarone-treated patients with type 2 diabetes: patients with treated overt hypothyroidism (group I, n=15), patients with untreated subclinical hypothyroidism (group II, n=15), and subjects without thyroid disorders (group III, n=18)." | 3.83 | The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and amiodarone-induced hypothyroidism. ( Gilowska, M; Krysiak, R; Okopień, B; Szkróbka, W, 2016) |
"To evaluate the frequency with which hypothyroidism is associated with Type 2 diabetes, to examine gender and ethnic group differences, and to assess the possible impact of metformin therapy." | 3.80 | Type 2 diabetes mellitus and hypothyroidism: the possible influence of metformin therapy. ( Distiller, LA; Joffe, BI; Polakow, ES, 2014) |
"Serum total bilirubin, thyrotropin and free thyroxine (free T4), transaminases, insulin sensitivity (homeostasis model assessment), and lipids were measured in 74 T2DM and 82 nondiabetic subjects with thyrotropin and free T4 levels within the euthyroid range." | 3.79 | Low-normal free thyroxine confers decreased serum bilirubin in type 2 diabetes mellitus. ( Bakker, SJ; Deetman, PE; Dullaart, RP; Kwakernaak, AJ, 2013) |
" In all subjects, thyroid stimulating hormone (TSH), free thyroxine (FT4), fasting plasma levels of insulin and glucose, homeostasis model assessment for insulin resistance, and obesity parameters were assessed." | 3.79 | Relationship of thyroid function with obesity and type 2 diabetes in euthyroid Tunisian subjects. ( Abid, H; Ammar, M; Bchir, F; Berhouma, R; Clerget-Froidevaux, MS; Demeneix, B; Elgaaied, AB; Guissouma, H; Jarboui, S; Kouidhi, S; Rouissi, K; Seugnet, I, 2013) |
"Our results favour screening for hypothyroidism in patients with Type 2 diabetes older than 65 years, especially in the presence of diabetic macroangiopathy or treatment with metformin." | 3.78 | An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes. ( Díez, JJ; Iglesias, P, 2012) |
"Prolonged hypoglycemia induced by acetohexamide (AH) in a patient with noninsulin dependent diabetes mellitus accompanied by primary hypothyroidism was presented." | 3.68 | A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide. ( Shibutani, Y; Yokota, T, 1991) |
"Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with type 2 diabetes mellitus (T2DM) and associated with significant morbidity and mortality." | 2.87 | Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD. ( Angus, PW; Bee, YM; Bruinstroop, E; Burrell, LM; Cao, Y; Chandran, K; Cho, LW; Dalan, R; Leow, MKS; Leung, C; Lim, SC; Michael, N; Patel, SK; Sadananthan, SA; Sinha, RA; Soh, SB; Stapleton, HM; Sum, CF; Teo, EK; Toh, SA; Velan, SS; Yen, PM, 2018) |
"Osteoporosis is a skeletal disorder characterized by decreased mass and compromised bone strength predisposing to an increased risk of fractures." | 2.52 | Management of endocrine disease: Secondary osteoporosis: pathophysiology and management. ( Canalis, E; Mirza, F, 2015) |
"Patients with thyroid cancer who underwent thyroidectomy had a higher risk of developing type 2 diabetes mellitus than the matched controls (hazard ratio [HR] 1." | 1.72 | Increased Risk of Type 2 Diabetes in Patients With Thyroid Cancer After Thyroidectomy: A Nationwide Cohort Study. ( Baik, SH; Cho, GJ; Choi, KM; Hwang, SY; Kim, JA; Noh, E; Park, M; Roh, E; Song, E; Yoo, HJ, 2022) |
"Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function." | 1.72 | Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan. ( Hsieh, YS; Hsu, CH; Huang, CL; Lee, YW; Lin, YP; Lin, YY; Weng, SF, 2022) |
"Patients with type 2 diabetes are tested for thyroid function in view of the associated weight gain, IR, and changes in metabolism." | 1.62 | The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus. ( Kamenov, Z; Yanachkova, V, 2021) |
"Patients with type 2 diabetes mellitus (T2DM) are at a higher risk of sarcopenia." | 1.56 | A cross-sectional study: Associations between sarcopenia and clinical characteristics of patients with type 2 diabetes. ( Cui, M; Gang, X; Jiang, Z; Li, Z; Wang, G; Xiao, X, 2020) |
"Thyroid function and type 2 diabetes mellitus (T2DM) are both associated with increased risks of adverse clinical outcomes in nonalcoholic fatty liver disease (NAFLD)." | 1.56 | Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. ( Huang, B; Yang, S; Ye, S, 2020) |
"Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA)." | 1.51 | Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus. ( Anothaisintawee, T; Chailurkit, LO; Chirakalwasan, N; Manodpitipong, A; Nimitphong, H; Pinyopodjanard, S; Reutrakul, S; Saetang, S; Siwasaranond, N; Sriphrapradang, C; Suntornlohanakul, O, 2019) |
"He had a history of thyroid cancer but did not have diabetes mellitus." | 1.51 | Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report. ( Kim, EY; Kim, JJ, 2019) |
"The incidence of cerebral infarction is increased in patients with NFPA irrespective of GHRT." | 1.48 | Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement ( Bengtsson, O; Bryngelsson, IL; Hammarstrand, C; Johannsson, G; Olsson, DS; Ragnarsson, O, 2018) |
"Diabetic nephropathy was diagnosed based on abnormal 24-h urinary albumin or protein measurements (24-h urinary albumin ≥30 mg/day or 24-h urinary protein ≥150 mg/day)." | 1.46 | Subclinical hypothyroidism and diabetic nephropathy in Iranian patients with type 2 diabetes. ( Hazrati, E; Heidari, Z; Mansournia, MA; Mansournia, N; Riahi, M; Riyahi, S; Tofangchiha, S, 2017) |
"Plasma PRCP levels are elevated in type 2 diabetes (T2D) mellitus and cardiovascular diseases." | 1.46 | Altered Prolylcarboxypeptidase Expression and Function in Response to Different Risk Factors of Diabetes. ( Floyd, L; Shariat-Madar, Z; Tabrizian, T, 2017) |
"Here, subclinical hypothyroidism is 5." | 1.46 | Study of Thyroid Disorders among Type 2 Diabetic Patients Attending a Tertiary Care Hospital. ( Khan, NZ; Mishu, FA; Muttalib, MA; Nesa, A; Sultana, GS, 2017) |
"Overt hypothyroidism is frequently found in patients with type 2 diabetes mellitus (T2DM), but it remains unknown the relationship between subclinical hypothyroidism (SCH) and T2DM." | 1.43 | Poor glycemic control is associated with the risk of subclinical hypothyroidism in patients with type 2 diabetes mellitus. ( Cho, JH; Kim, HJ; Lee, HW; Lee, IK; Lee, JH; Moon, JS; Park, IR; Won, KC; Yoon, JS, 2016) |
"Metabolic syndrome has been associated with nodular goiter." | 1.42 | Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome. ( Barreto, A; Blanc, E; Brenta, G; Brodschi, D; Cejas, C; Faingold, C; Fossati, P; Musso, C; Nepote, A; Ponce, C; Salgado, P; Schnitman, M, 2015) |
"Seventy subjects with Type 2 diabetes mellitus (T2DM), 37 subjects with impaired fasting glucose (IFG) and 31 subjects with normal fasting glucose (NFG) (revised NCEP-ATPIII criteria) participated in a cross-sectional study." | 1.39 | Low normal free T4 confers decreased high-density lipoprotein antioxidative functionality in the context of hyperglycaemia. ( Annema, W; de Boer, JF; Dullaart, RP; Kwakernaak, AJ; Tietge, UJ; Triolo, M, 2013) |
" No differences in total levothyroxine dosage were found: 114 (100-150) [median (Q1-Q3)] μg in the non-MF group versus 125 (100-142) μg in the MF group (p=0." | 1.39 | Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment? ( Casteràs, A; Ciudin, A; Mesa, J; Zafon, C, 2013) |
"Neonatal hypothyroidism has serious effects on growth, development, and metabolism." | 1.39 | Effect of neonatal hypothyroidism on carbohydrate metabolism, insulin secretion, and pancreatic islets morphology of adult male offspring in rats. ( Farahani, H; Ghasemi, A; Roghani, M; Zahediasl, S, 2013) |
"Metformin therapy was a nonsignificant variable in this model." | 1.39 | Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes. ( Díez, JJ; Iglesias, P, 2013) |
"Patients with type 2 diabetes had significantly lower serum FT3 levels (p = 0." | 1.35 | A comparative study of thyroid hormone levels in diabetic and non-diabetic patients. ( Alam, NH; Islam, S; Khan, SA; Yesmine, S, 2008) |
"Rosiglitazone was administered to dexamethasone-induced hyperglycaemic male mice and the alterations in serum concentrations of thyroid hormones insulin, total cholesterol, triglycerides and fasting glucose were studied." | 1.34 | Amelioration of corticosteroid-induced type 2 diabetes mellitus by rosiglitazone is possibly mediated through stimulation of thyroid function and inhibition of tissue lipid peroxidation in mice. ( Jatwa, R; Kar, A; Panda, S; Parmar, HS, 2007) |
"In women with type 2 diabetes without known thyroid disease, subclinical hypothyroidism is a common but incidental finding." | 1.33 | Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study. ( Chubb, SA; Davis, TM; Davis, WA; Inman, Z, 2005) |
"Primary hypothyroidism and type 2 diabetes are both typically associated with the increased level of triglycerides." | 1.33 | A case of hypothyroidism and type 2 diabetes associated with type V hyperlipoproteinemia and eruptive xanthomas. ( Chang, SH; Chung, SI; Hahm, JR; Jung, JH; Jung, TS; Kim, DR; Kim, MA; Lee, GW; Park, JR; Park, KJ, 2005) |
"Female patients with Type 1 diabetes had the highest annual risk of developing thyroid disease (12." | 1.29 | Frequency of thyroid dysfunction in diabetic patients: value of annual screening. ( Frier, BM; McCrimmon, RJ; Perros, P; Shaw, G, 1995) |
"Elderly men with NIDDM had even lower serum testosterone levels compared with elderly men without NIDDM." | 1.29 | Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity. ( Chang, TC; Hsiao, YL; Tung, CC, 1994) |
"In contrast to the changes observed in IDDM, NIDDM increased both Kd and Bmax values." | 1.29 | Different [3H]ouabain binding characteristics of fast and slow skeletal muscles in IDDM and NIDDM diabetic rats. ( Bányász, T; Kovács, T, 1996) |
"Patients with Type 2 diabetes, autoimmune diabetes and Type 1 diabetes showed a 47%, 45% and 42%, respectively, reduction in the rate of non-oxidative glucose metabolism compared with control subjects (p less than 0." | 1.28 | Metabolic characteristics of autoimmune diabetes mellitus in adults. ( Ekstrand, A; Eriksson, J; Franssila-Kallunki, A; Groop, LC; Miettinen, A; Saloranta, C, 1991) |
"Examination of cells from patients with NIDDM revealed an increased thyroid hormone induced glucose uptake, indicating increased thyroid hormone sensitivity." | 1.28 | Thyroid hormone stimulated glucose uptake in human mononuclear blood cells from normal persons and from patients with non-insulin-dependent diabetes mellitus. ( Kvetny, J; Matzen, L, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (10.26) | 18.7374 |
1990's | 6 (5.13) | 18.2507 |
2000's | 17 (14.53) | 29.6817 |
2010's | 52 (44.44) | 24.3611 |
2020's | 30 (25.64) | 2.80 |
Authors | Studies |
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Li, P | 1 |
Ding, L | 1 |
Zhen, J | 1 |
Hu, J | 1 |
Fan, Y | 1 |
Liu, M | 1 |
Roh, E | 1 |
Noh, E | 1 |
Hwang, SY | 1 |
Kim, JA | 1 |
Song, E | 1 |
Park, M | 1 |
Choi, KM | 1 |
Baik, SH | 1 |
Cho, GJ | 1 |
Yoo, HJ | 1 |
Sun, X | 2 |
Chen, L | 2 |
Wu, R | 1 |
Zhang, D | 1 |
He, Y | 1 |
Roa Dueñas, OH | 1 |
Van der Burgh, AC | 1 |
Ittermann, T | 2 |
Ligthart, S | 1 |
Ikram, MA | 1 |
Peeters, R | 1 |
Chaker, L | 1 |
Zhang, Y | 2 |
Li, J | 1 |
Liu, H | 1 |
Alonso-Ventura, V | 1 |
Civeira, F | 1 |
Alvarado-Rosas, A | 1 |
Lou-Bonafonte, JM | 1 |
Calmarza, P | 1 |
Moreno-Franco, B | 1 |
Andres-Otero, MJ | 1 |
Calvo-Gracia, F | 1 |
de Diego-Garcia, P | 1 |
Laclaustra, M | 1 |
Gong, L | 1 |
Ma, A | 1 |
Yin, X | 1 |
Liang, K | 1 |
Liu, J | 2 |
Lee, YW | 1 |
Lin, YY | 1 |
Weng, SF | 1 |
Hsu, CH | 1 |
Huang, CL | 1 |
Lin, YP | 1 |
Hsieh, YS | 1 |
Chubb, SAP | 2 |
Peters, KE | 2 |
Bruce, DG | 2 |
Davis, WA | 3 |
Davis, TME | 2 |
Banimfreg, BH | 1 |
Shamayleh, A | 1 |
Alshraideh, H | 1 |
Semreen, MH | 1 |
Soares, NC | 1 |
Okada, S | 2 |
Isoda, A | 2 |
Hoshi, H | 2 |
Okada, J | 2 |
Okada, K | 2 |
Yamada, E | 2 |
Saito, T | 2 |
Watanabe, T | 2 |
Kikkawa, K | 1 |
Ohshima, K | 2 |
V, BV | 1 |
Shrestha, B | 1 |
Rai, CK | 1 |
Csiha, S | 1 |
Molnár, I | 1 |
Halmi, S | 1 |
Hutkai, D | 1 |
Lőrincz, H | 1 |
Somodi, S | 1 |
Katkó, M | 1 |
Harangi, M | 1 |
Paragh, G | 1 |
Nagy, EV | 1 |
Berta, E | 1 |
Bodor, M | 1 |
Lin, L | 1 |
Du, Y | 1 |
Niu, G | 1 |
Xia, S | 1 |
Amirabadizadeh, A | 1 |
Amouzegar, A | 1 |
Mehran, L | 1 |
Azizi, F | 1 |
Banihani, SA | 1 |
Makahleh, SM | 1 |
El-Akawi, ZJ | 1 |
Cui, M | 1 |
Gang, X | 1 |
Wang, G | 3 |
Xiao, X | 1 |
Li, Z | 1 |
Jiang, Z | 1 |
Dutka, R | 1 |
Chmyr, N | 1 |
Svitlyk, H | 1 |
Leontieva, Z | 1 |
Li, Q | 2 |
Lu, M | 1 |
Wang, NJ | 1 |
Chen, Y | 2 |
Chen, YC | 1 |
Han, B | 1 |
Xia, FZ | 1 |
Jiang, BR | 1 |
Zhai, HL | 1 |
Lin, DP | 1 |
Lu, YL | 1 |
Xiu, S | 1 |
Mu, Z | 1 |
Zhao, L | 1 |
Sun, L | 1 |
Goonoo, MS | 1 |
Morris, R | 1 |
Raithatha, A | 1 |
Creagh, F | 1 |
Huang, B | 1 |
Yang, S | 1 |
Ye, S | 1 |
Gu, L | 1 |
Yang, J | 1 |
Gong, Y | 2 |
Ma, Y | 1 |
Yan, S | 1 |
Huang, Y | 1 |
Wang, Y | 2 |
Peng, Y | 1 |
Yao, Z | 1 |
Zhao, M | 1 |
Chen, W | 1 |
Wang, Q | 1 |
Fu, Y | 1 |
Guo, T | 1 |
Zhao, J | 3 |
Gao, L | 1 |
Bo, T | 1 |
Zhang, M | 1 |
Xiang, S | 1 |
Jiang, X | 1 |
Gu, H | 2 |
Sha, Q | 1 |
Qu, M | 1 |
Xu, T | 1 |
Yanachkova, V | 1 |
Kamenov, Z | 1 |
Stedman, M | 1 |
Taylor, P | 1 |
Premawardhana, L | 1 |
Okosieme, O | 1 |
Dayan, C | 1 |
Heald, AH | 1 |
Andersen, MS | 1 |
Jensen, TK | 1 |
Dreyer, AF | 1 |
Madsen, JB | 1 |
Christesen, HT | 1 |
Brandslund, I | 1 |
Bilenberg, N | 1 |
Glintborg, D | 1 |
Nakajima, Y | 1 |
Ozawa, A | 1 |
Yamada, M | 1 |
Bos, MM | 1 |
Smit, RAJ | 1 |
Trompet, S | 1 |
van Heemst, D | 1 |
Noordam, R | 1 |
Liu, F | 3 |
Di, J | 1 |
Yu, H | 1 |
Han, J | 1 |
Bao, Y | 2 |
Jia, W | 2 |
Wu, G | 1 |
Xu, M | 1 |
Khan, NZ | 1 |
Muttalib, MA | 1 |
Sultana, GS | 1 |
Mishu, FA | 1 |
Nesa, A | 1 |
Schipf, S | 1 |
Dörr, M | 1 |
Thuesen, BH | 1 |
Jørgensen, T | 1 |
Völzke, H | 1 |
Markus, MRP | 1 |
van Tienhoven-Wind, LJN | 1 |
Tietge, UJF | 1 |
Dullaart, RPF | 1 |
Seo, C | 1 |
Kim, S | 1 |
Lee, M | 1 |
Cha, MU | 1 |
Kim, H | 1 |
Park, S | 1 |
Yun, HR | 1 |
Jhee, JH | 1 |
Kee, YK | 1 |
Han, SH | 1 |
Yoo, TH | 1 |
Kang, SW | 1 |
Park, JT | 1 |
Bruinstroop, E | 1 |
Dalan, R | 1 |
Cao, Y | 1 |
Bee, YM | 1 |
Chandran, K | 1 |
Cho, LW | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
Effects of Long-term L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Patients With Hypothyroidism[NCT01848171] | Phase 4 | 700 participants (Anticipated) | Interventional | 2013-07-31 | Active, not recruiting | ||
Effects of 4-month Therapy of Levothyroxine on Non-Alcoholic Fatty Liver Disease (NAFLD) and Diabetes Control in Diabetic Patients[NCT03281083] | Phase 2 | 29 participants (Actual) | Interventional | 2014-03-28 | Terminated (stopped due to Difficult recruitment and end of funding.) | ||
Prospective and Multi-centric Study on Diabetes During Pregnancy in Belgium[NCT02036619] | 2,006 participants (Actual) | Observational | 2014-04-30 | Completed | |||
The Effect of Ingestion of Foods on the Plasma Glucose and Insulin Response in Subjects With Type 2 Diabetes: Protein, Amino Acids & Insulin & Glucagon Secretion in Humans[NCT01471509] | 300 participants (Anticipated) | Interventional | 1982-08-31 | Suspended (stopped due to Lack of funding) | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 reviews available for thyroxine and Diabetes Mellitus, Adult-Onset
Article | Year |
---|---|
Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes.
Topics: Diabetes Mellitus, Type 2; Humans; Hyperthyroidism; Hypothyroidism; Prediabetic State; Prospective S | 2022 |
The effect of metformin therapy on serum thyrotropin and free thyroxine concentrations in patients with type 2 diabetes: a meta-analysis.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Metformin; Thyroid Hormones; T | 2023 |
Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Humans; Hypothyroidism; Mutation; Postp | 2018 |
Management of endocrine disease: Secondary osteoporosis: pathophysiology and management.
Topics: Acromegaly; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Autoimmune Diseases; Celiac Disea | 2015 |
Hormones and lipoprotein metabolism.
Topics: Catecholamines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucocortico | 1987 |
10 trials available for thyroxine and Diabetes Mellitus, Adult-Onset
Article | Year |
---|---|
The relationship between thyroid dysfunction, cardiovascular morbidity and mortality in type 2 diabetes: The Fremantle Diabetes Study Phase II.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Myocardial Infarction; Stroke | 2022 |
Short-term Effect of Fresh Pomegranate Juice on Serum Cortisol and Thyroxine in Patients with type 2 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Fruit and Vegetable Juices; Humans; H | 2020 |
The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Albuminuria; Creatinine; Deoxyguanosine; Diabetes Mellitus, Type | 2018 |
Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Lipids; Liver; Male; Middle Aged; Non-alcoholic Fatty Live | 2018 |
Topics: Adult; Aged; Animals; Astrocytes; Bariatric Surgery; Beta vulgaris; Bioreactors; Biotechnology; Bloo | 2018 |
TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients.
Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Thyroid Diseases; | 2009 |
Effects of hormone replacement therapy with vitamin C and E supplementation on plasma thyroid hormone levels in postmenopausal women with Type 2 diabetes.
Topics: Aged; Antioxidants; Ascorbic Acid; Diabetes Mellitus, Type 2; Female; Hormone Replacement Therapy; H | 2009 |
The metabolic response to a high-protein, low-carbohydrate diet in men with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Aldosterone; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet | 2006 |
Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy.
Topics: Aged; Body Weight; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agen | 2007 |
Effects of somatostatin analogue SMS 201-995 in non-insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Glucagon; Growth Hormone; Humans; Insulin; Male; Mi | 1986 |
102 other studies available for thyroxine and Diabetes Mellitus, Adult-Onset
Article | Year |
---|---|
Association of subtle alterations in thyroid function with presarcopenia in patients with type 2 diabetes mellitus.
Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Hyperthyroidism; Hypothyroidism; | 2022 |
Increased Risk of Type 2 Diabetes in Patients With Thyroid Cancer After Thyroidectomy: A Nationwide Cohort Study.
Topics: Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Fo | 2022 |
Association of thyroid hormone with body fat content and lipid metabolism in euthyroid male patients with type 2 diabetes mellitus: a cross-sectional study.
Topics: Adipose Tissue; Adult; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; | 2021 |
Correlation between the thyroid hormone levels and nonalcoholic fatty liver disease in type 2 diabetic patients with normal thyroid function.
Topics: Diabetes Mellitus, Type 2; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Retrospective | 2022 |
A Cross-Sectional Study Examining the Parametric Thyroid Feedback Quantile Index and Its Relationship with Metabolic and Cardiovascular Diseases.
Topics: Adult; Atrial Fibrillation; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Typ | 2022 |
Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes.
Topics: C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Obesity; Thyroid Function Tes | 2022 |
Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Cross-Sectional Studies; Diabetes Mel | 2022 |
Untargeted approach to investigating the metabolomics profile of type 2 diabetes emiratis.
Topics: Bile Acids and Salts; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Glycated Hemoglob | 2022 |
The ratio of free triiodothyronine to free thyroxine is regulated differently in patients with type 2 diabetes mellitus treated and not treated with sodium glucose cotransporter 2 inhibitors.
Topics: Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Retrospective Studies; Sodium-Gl | 2023 |
A Case of Autoimmune Poly Glandular Glandular Syndrome Type 2 (Schmidt's Syndrome).
Topics: Addison Disease; Adult; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Humans; Male; Polyendo | 2023 |
Hypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Middle Age | 2023 |
Advanced glycation end products and their soluble receptor (sRAGE) in patients with Hashimoto's thyroiditis on levothyroxine substitution.
Topics: Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Hashimoto Disease; Humans; Thyrotropin; | 2023 |
Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Folic Acid; Humans; Thyroid Diseases; Thyroid Hormones; Thyrotropin; Thyr | 2023 |
A cross-sectional study: Associations between sarcopenia and clinical characteristics of patients with type 2 diabetes.
Topics: Age Factors; Aged; Aged, 80 and over; Body Composition; Body Mass Index; China; Cross-Sectional Stud | 2020 |
Prevalence and incidence of thyroid dysfunction in type 1 diabetes, type 2 diabetes and latent autoimmune diabetes of adults: The Fremantle Diabetes Study Phase II.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Hyperthyroidism; Incidence; Lat | 2020 |
PROLACTIN, CORTISOL, FREE THYROXINE AND THYROID-STIMULATING HORMONE - MARKERS OF STAGING OF METABOLIC SYNDROME AS A RISK FACTOR OF CORONARY ARTERY DISEASE AND TYPE 2 DIABETES MELLITUS.
Topics: Biomarkers; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Hydrocortisone; Meta | 2019 |
Relationship between Free Thyroxine and Islet Beta-cell Function in Euthyroid Subjects.
Topics: Adult; Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter, Nodular; Humans; In | 2020 |
Low free triiodothyronine levels are associated with risk of frailty in older adults with type 2 diabetes mellitus.
Topics: Aged; Diabetes Mellitus, Type 2; Frailty; Hand Strength; Humans; Thyroid Function Tests; Thyrotropin | 2020 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Middle Aged; Non-a | 2020 |
Lower free thyroid hormone levels are associated with high blood glucose and insulin resistance; these normalize with metabolic improvement of type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Cross-Sectional Studies; Diabet | 2021 |
Relation of Gut Microbes and L-Thyroxine Through Altered Thyroxine Metabolism in Subclinical Hypothyroidism Subjects.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Gastrointestinal Microbiome; Humans; Hyp | 2020 |
Association Between Thyroid Function and Body Composition in Type 2 Diabetes Mellitus (T2DM) Patients: Does Sex Have a Role?
Topics: Algorithms; Body Composition; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Propensi | 2021 |
The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; Retrospective Studies; | 2021 |
Liothyronine and levothyroxine prescribing in England: A comprehensive survey and evaluation.
Topics: Diabetes Mellitus, Type 2; Female; General Practice; Hormone Replacement Therapy; Humans; Practice P | 2021 |
Free thyroxine in early pregnancy is an independent negative predictor of 3rd trimester HbA1c. Odense child cohort.
Topics: Child; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Pregnancy; Pregnancy Trimeste | 2021 |
Free triiodothyronine /free thyroxine ratio as an index of deiodinase type 1 and 2 activities negatively correlates with casual serum insulin levels in patients with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Huma | 2021 |
Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study.
Topics: Alleles; Blood Glucose; Databases, Factual; Diabetes Mellitus, Type 2; Genetic Variation; Genome-Wid | 2017 |
Effect of Roux-en-Y gastric bypass on thyroid function in euthyroid patients with obesity and type 2 diabetes.
Topics: Adult; Body Mass Index; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Humans; Male; Middle Aged | 2017 |
Study of Thyroid Disorders among Type 2 Diabetic Patients Attending a Tertiary Care Hospital.
Topics: Bangladesh; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hyperthyroidism; Hyp | 2017 |
Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Denmark; Diabetes Mellitus, Type 2; Female; German | 2018 |
The HDL anti-inflammatory function is impaired in the context of low-normal free thyroxine in diabetic and nondiabetic individuals.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Thyrotropin; | 2018 |
THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM.
Topics: Aged; Asymptomatic Diseases; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathi | 2018 |
Thyroid status in premenopausal and postmenopausal women - A biochemical study on insulin resistance in non obese, overweight and obese type 2 diabetics.
Topics: Adult; Aged; Anthropometry; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Middle Ag | 2018 |
Prevalence of β-cell antibodies and associated autoimmune diseases in children and adolescents with type 1 diabetes (T1DM) versus type 2 diabetes (T2DM) in Qatar.
Topics: Adolescent; Autoantibodies; Autoantigens; Autoimmune Diseases; Child; Child, Preschool; Comorbidity; | 2018 |
Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement
Topics: Adenoma; Adult; Aged; Cerebral Infarction; Cohort Studies; Comorbidity; Diabetes Mellitus, Type 2; F | 2018 |
Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Middle Aged; Prediabetic Sta | 2019 |
Cognitive function in hypothyroidism: what is that deiodinase again?
Topics: Brain; Cognition; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Iodide Peroxidase; Thyroxine; T | 2019 |
Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report.
Topics: Adult; Blood Gas Analysis; Coma; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Glycated Hemoglob | 2019 |
Low normal thyroid function enhances plasma cholesteryl ester transfer in Type 2 diabetes mellitus.
Topics: Aged; Biomarkers; Blood Glucose; Case-Control Studies; Chi-Square Distribution; Cholesterol Ester Tr | 2013 |
Low-normal free thyroxine confers decreased serum bilirubin in type 2 diabetes mellitus.
Topics: Aged; Antioxidants; Aspartate Aminotransferases; Atherosclerosis; Bilirubin; Cholesterol; Diabetes M | 2013 |
Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment?
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; | 2013 |
[Effects of thyroid hormone on islet β cell function among type 2 diabetics with normal thyroid function].
Topics: Diabetes Mellitus, Type 2; Female; Humans; Islets of Langerhans; Male; Middle Aged; Risk Factors; Th | 2013 |
The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction, and body height: the Tromsø study.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Body Height; Cardiovascular Diseases; Diabetes Mel | 2014 |
Human herpes virus associated with Hashimoto's thyroiditis.
Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Herpes Labialis; Humans; Im | 2013 |
Type 2 diabetes mellitus and hypothyroidism: the possible influence of metformin therapy.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Diabetes Mellitus, Type 2; Ethnicity; Female; Hormon | 2014 |
The Belgian Diabetes in Pregnancy Study (BEDIP-N), a multi-centric prospective cohort study on screening for diabetes in pregnancy and gestational diabetes: methodology and design.
Topics: Adolescent; Adult; Belgium; Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; | 2014 |
The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and subclinical hyperthyroidism.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperthyroidism; Hypogl | 2015 |
Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome.
Topics: Aged; Aged, 80 and over; Anthropometry; Argentina; Body Mass Index; Cohort Studies; Cross-Sectional | 2015 |
Pre-β-HDL formation relates to high-normal free thyroxine in type 2 diabetes mellitus.
Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; High-Density Lipoproteins, Pre-beta; | 2016 |
[FT4 immunoassay interference : A case report].
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Humans; Hyperthyroidism; Immunoassay; Male; Sheep; Thyroid | 2015 |
Association of Hypothyroidism with Body Mass Index, Systolic Blood Pressure and Proteinuria in Diabetic Patients: Does treated Hypothyroidism with Thyroxine Replacement Therapy Prevent Nephropathy/Chronic Renal Disease?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Di | 2016 |
A high thyroid stimulating hormone level is associated with diabetic peripheral neuropathy in type 2 diabetes patients.
Topics: Aged; Biomarkers; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; | 2016 |
The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and amiodarone-induced hypothyroidism.
Topics: Aged; Amiodarone; Diabetes Mellitus, Type 2; Female; Humans; Hypothalamo-Hypophyseal System; Hypothy | 2016 |
Malabsorption of L-T4 Due to Drip Coffee: A Case Report Using Predictors of Causation.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Drug Interactions; Fasting; Female; Hashimoto Disease; | 2016 |
Poor glycemic control is associated with the risk of subclinical hypothyroidism in patients with type 2 diabetes mellitus.
Topics: Adult; Age Distribution; Aged; Asymptomatic Diseases; Biomarkers; Blood Glucose; Chi-Square Distribu | 2016 |
Improvement of Metabolic Parameters Resulted from Levothyroxine Therapy in Hypothyroid Type 2 Diabetes Mellitus Patient.
Topics: Blood Glucose; Blood Pressure; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, T | 2016 |
Subclinical hypothyroidism and diabetic nephropathy in Iranian patients with type 2 diabetes.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypothyr | 2017 |
Association Between Changes in Thyroid Hormones and Incident Type 2 Diabetes: A Seven-Year Longitudinal Study.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Incidence; Longitudinal Studies; Male; Middle Aged | 2017 |
Tumor Necrosis Factor-α is Inversely Related to Free Thyroxine in Euthyroid Subjects Without Diabetes.
Topics: Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; | 2017 |
The Relationship Between Thyroid Function and the Prevalence of Type 2 Diabetes Mellitus in Euthyroid Subjects.
Topics: Adult; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; | 2017 |
Altered Prolylcarboxypeptidase Expression and Function in Response to Different Risk Factors of Diabetes.
Topics: Animals; Carboxypeptidases; Cardiovascular Diseases; Cell Survival; Cells, Cultured; Diabetes Mellit | 2017 |
A comparative study of thyroid hormone levels in diabetic and non-diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Immunoenzyme Techniques | 2008 |
Amelioration of metformin-induced hypothyroidism by Withania somnifera and Bauhinia purpurea extracts in Type 2 diabetic mice.
Topics: Animals; Bauhinia; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female | 2009 |
Thyroid hormones are positively associated with insulin resistance early in the development of type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Food; Glucose Intolerance; Humans; | 2011 |
Thyrotropin-lowering effect of metformin in a patient with resistance to thyroid hormone.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Male; Metformin; Thyroid Hormone Resistanc | 2011 |
The rate of primary hypothyroidism in diabetic patients is greater than in the non-diabetic population. An observational study.
Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hyp | 2012 |
Plasma testosterone in adult normoglycaemic men: impact of hyperinsulinaemia.
Topics: Adult; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Humans; Hydroc | 2012 |
An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes.
Topics: Aged; Autoantibodies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Hypoglycemic Agents; Hypot | 2012 |
Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes.
Topics: Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter; Huma | 2013 |
Effect of neonatal hypothyroidism on carbohydrate metabolism, insulin secretion, and pancreatic islets morphology of adult male offspring in rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Female | 2013 |
An unusual case of stroke.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diuretics; Female; Furo | 2012 |
Relationship of thyroid function with obesity and type 2 diabetes in euthyroid Tunisian subjects.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Resistance; Male; Metabol | 2013 |
[Impact of replacement therapy for subclinical hypothyroidism on cardiovascular risk markers in patients with type 2 diabetes mellitus].
Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; Cholesterol; Diabetes Mellitus, Type 2; Dis | 2012 |
Low normal free T4 confers decreased high-density lipoprotein antioxidative functionality in the context of hyperglycaemia.
Topics: Aged; Antioxidants; Atherosclerosis; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Diabet | 2013 |
Treatment of hyperlipemic diabetic patients. Effects of dextro-thyroxine therapy.
Topics: Cholesterol, HDL; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypoglycemi | 1963 |
LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin.
Topics: Animals; Basal Metabolism; Body Composition; Body Temperature Regulation; Body Weight; Calorimetry, | 2004 |
Increased adiposity and reduced adipose tissue mRNA expression of uncoupling protein-2 in first-degree relatives of type 2 diabetic patients: evidence for insulin stimulation of UCP-2 and UCP-3 gene expression in adipose tissue.
Topics: Adipose Tissue; Adult; Body Composition; Calorimetry, Indirect; Carrier Proteins; Case-Control Studi | 2005 |
Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study.
Topics: Adult; Autoantibodies; Biomarkers; Blood Glucose; Cholesterol; Cholesterol, HDL; Cross-Sectional Stu | 2005 |
A case of hypothyroidism and type 2 diabetes associated with type V hyperlipoproteinemia and eruptive xanthomas.
Topics: Diabetes Mellitus, Type 2; Erythrocyte Aggregation; Female; Fenofibrate; Humans; Hyperlipidemias; Hy | 2005 |
Antihyperglycaemic and antiperoxidative roles of acarbose in type 2 diabetes mellitus are possibly mediated through changes in thyroid function.
Topics: Acarbose; Animals; Antioxidants; Blood Glucose; Catalase; Dexamethasone; Diabetes Mellitus, Experime | 2006 |
Obesity increases free thyroxine proportionally to nonesterified fatty acid concentrations in adult neutered female cats.
Topics: Animals; Cats; Diabetes Mellitus, Type 2; Disease Progression; Fatty Acids, Nonesterified; Female; I | 2007 |
Amelioration of corticosteroid-induced type 2 diabetes mellitus by rosiglitazone is possibly mediated through stimulation of thyroid function and inhibition of tissue lipid peroxidation in mice.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Dexamethasone; Diabetes Mellitus, Experimental; Diabe | 2007 |
Subclinical hypothyroidism is a risk factor for nephropathy and cardiovascular diseases in Type 2 diabetic patients.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; D | 2007 |
Impaired pituitary thyrotroph function in uncontrolled type II diabetes mellitus: normalization on recovery.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Humans; Insulin; Male; Middle Aged; Pituitary Gland, Anter | 1984 |
Low triiodothyronine and raised reverse triiodothyronine levels in patients over fifty years of age who have type II diabetes mellitus: influence of metabolic control, not age.
Topics: Adult; Aged; Aging; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; Thyrotropin | 1984 |
Frequency of thyroid dysfunction in diabetic patients: value of annual screening.
Topics: Adult; Ambulatory Care Facilities; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Hum | 1995 |
Prevalence of abnormal thyrotropin concentrations measured by a sensitive assay in patients with type 2 diabetes mellitus.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Autoantibodies; Body Mass Index; Diabetes Mellitus, Typ | 1994 |
Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity.
Topics: Abdomen; Adipose Tissue; Adult; Aged; Aging; Body Constitution; Diabetes Mellitus, Type 2; Follicle | 1994 |
Different [3H]ouabain binding characteristics of fast and slow skeletal muscles in IDDM and NIDDM diabetic rats.
Topics: Aging; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type | 1996 |
Prevalence of hypothyroidism and diabetes mellitus in elderly kibbutz members.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Cohort Studies; Cross-Sectional Studies; | 2000 |
Endocrine and metabolism: 2000.
Topics: Diabetes Mellitus, Type 2; Endocrinology; Humans; Metabolism; Thyrotropin; Thyroxine | 2000 |
A falling HbA1c is not necessarily an indicator of improving diabetes control.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Female; Flupenthixol; Glycated Hemoglobin; Hemoglobins; Hemol | 2001 |
A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide.
Topics: Acetohexamide; Aged; Diabetes Mellitus, Type 2; Half-Life; Humans; Hypoglycemia; Hypothyroidism; Mal | 1991 |
Metabolic characteristics of autoimmune diabetes mellitus in adults.
Topics: Adult; Autoantibodies; Autoimmune Diseases; Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus | 1991 |
Thyroid hormone stimulated glucose uptake in human mononuclear blood cells from normal persons and from patients with non-insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Middle Aged; Oxygen Consumption | 1989 |
Stimulation of thyroid adenylate cyclase activity by sera from patients with non-thyroidal illness.
Topics: Adenylyl Cyclases; Cell Line; Collagen Diseases; Culture Media; Cyclic AMP; Diabetes Mellitus, Type | 1986 |
Decreased thyroidal response to thyrotropin in type II diabetes mellitus.
Topics: Adult; Animals; Cattle; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Thyroid Gland; | 1988 |
Thyroid hormones in non-insulin dependent diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronin | 1988 |
[Basal blood level of thyroxine in diabetes mellitus patients].
Topics: Adult; Aged; Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; D | 1987 |
[A 58-year-old type-II diabetic patient with severe insulin resistance].
Topics: Autoantibodies; Breast Neoplasms; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Insulin | 1987 |
[Changes in T4-deiodination in decompensated diabetes mellitus. The low-T3 syndrome].
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Male; Syndrome; Thyrotropin; T | 1985 |