thyroxine has been researched along with Depression, Postpartum in 15 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Depression, Postpartum: Depression in POSTPARTUM WOMEN, usually within four weeks after giving birth (PARTURITION). The degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (From DSM-IV, p386)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to examine the neurobehavioral profile of neonates who are born to women with hypothyroxinemia during early pregnancy." | 7.73 | Neonatal effects of maternal hypothyroxinemia during early pregnancy. ( Brouwers, EP; Crawford, S; Kooistra, L; Pop, VJ; van Baar, AL, 2006) |
| "Previously we found that late pregnancy total and free thyroxine (TT4, FT4) concentrations were negatively related to greater pre and/or postpartum depressive symptoms." | 3.83 | Late pregnancy thyroid-binding globulin predicts perinatal depression. ( Garcia, N; Johnson, J; Leserman, J; Meltzer-Brody, S; Pedersen, C; Stansbury, M, 2016) |
| "We previously found significantly higher T3-resin uptake and nearly significantly lower total thyroxine concentrations at 38 weeks of pregnancy in women with higher postpartum depression ratings." | 3.74 | Antenatal thyroid correlates of postpartum depression. ( Bunevicius, R; Hamer, RM; Johnson, JL; Leserman, J; Meltzer-Brody, S; Pedersen, CA; Silva, S, 2007) |
| "We sought to examine the neurobehavioral profile of neonates who are born to women with hypothyroxinemia during early pregnancy." | 3.73 | Neonatal effects of maternal hypothyroxinemia during early pregnancy. ( Brouwers, EP; Crawford, S; Kooistra, L; Pop, VJ; van Baar, AL, 2006) |
| "Postpartum depression was assessed with Edinburgh Postpartum Depression Scale at 2-month postpartum and Brief Symptom Inventory at 2-, 6-, and 36-month postpartum." | 3.01 | Association of gestational thyroid function and thyroid peroxidase antibody positivity with postpartum depression: a prospective cohort study and systematic literature review with meta-analysis. ( Bramer, WM; Citterio, V; Derakhshan, A; Jansen, TA; Korevaar, TIM; Osinga, JAJ; Persani, L; Sileo, F; Tiemeier, H; Visser, WE, 2023) |
| "Subjects took the Edinburgh Postnatal Depression Scale (EPDS) prenatally and at 4 weeks postpartum." | 1.35 | Postpartum thyroid measures and depressive symptomology: a pilot study. ( Beal, JM; DeMers, AM; McCoy, SJ; Payton, ME; Stewart, AL; Watson, GH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sileo, F | 1 |
| Osinga, JAJ | 1 |
| Visser, WE | 1 |
| Jansen, TA | 1 |
| Bramer, WM | 1 |
| Derakhshan, A | 1 |
| Citterio, V | 1 |
| Tiemeier, H | 1 |
| Persani, L | 1 |
| Korevaar, TIM | 1 |
| Li, D | 1 |
| Li, Y | 1 |
| Chen, Y | 1 |
| Li, H | 1 |
| She, Y | 1 |
| Zhang, X | 1 |
| Chen, S | 1 |
| Chen, W | 1 |
| Qiu, G | 1 |
| Huang, H | 1 |
| Zhang, S | 1 |
| Jalkanen, A | 1 |
| Saraste, M | 1 |
| Gfeller, A | 1 |
| Surcel, HM | 1 |
| Airas, L | 1 |
| Pedersen, C | 1 |
| Leserman, J | 2 |
| Garcia, N | 1 |
| Stansbury, M | 1 |
| Meltzer-Brody, S | 2 |
| Johnson, J | 1 |
| McCoy, SJ | 1 |
| Beal, JM | 1 |
| Payton, ME | 1 |
| Stewart, AL | 1 |
| DeMers, AM | 1 |
| Watson, GH | 1 |
| Plaza, A | 2 |
| Garcia-Esteve, L | 3 |
| Ascaso, C | 2 |
| Navarro, P | 2 |
| Gelabert, E | 2 |
| Halperin, I | 1 |
| Valdés, M | 2 |
| Martín-Santos, R | 3 |
| Albacar, G | 1 |
| Sans, T | 1 |
| Guillamat, R | 1 |
| Sanjuan, J | 1 |
| Cañellas, F | 1 |
| Carot, JM | 1 |
| Gratacòs, M | 1 |
| Bosch, J | 1 |
| Gaviria, A | 1 |
| Labad, A | 1 |
| Zotes, AG | 1 |
| Vilella, E | 1 |
| Le Donne, M | 1 |
| Settineri, S | 1 |
| Benvenga, S | 1 |
| Torres, A | 1 |
| Luisa Imaz, M | 1 |
| Takenaka, H | 1 |
| Harris, B | 2 |
| Lazarus, J | 2 |
| Kooistra, L | 1 |
| Crawford, S | 1 |
| van Baar, AL | 1 |
| Brouwers, EP | 1 |
| Pop, VJ | 1 |
| Pedersen, CA | 1 |
| Johnson, JL | 1 |
| Silva, S | 1 |
| Bunevicius, R | 1 |
| Hamer, RM | 1 |
| Kent, GN | 1 |
| Stuckey, BG | 1 |
| Allen, JR | 1 |
| Lambert, T | 1 |
| Gee, V | 1 |
| Oretti, R | 1 |
| Parkes, A | 1 |
| John, R | 1 |
| Richards, C | 1 |
| Newcombe, R | 1 |
| Hall, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Postpartum Thyroid Measures and Mood[NCT00565032] | 75 participants (Actual) | Observational | 2000-01-31 | Completed | |||
| Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers[NCT03638687] | 80 participants (Anticipated) | Observational | 2014-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thyroxine and Depression, Postpartum
| Article | Year |
|---|---|
Association of gestational thyroid function and thyroid peroxidase antibody positivity with postpartum depression: a prospective cohort study and systematic literature review with meta-analysis.
Topics: Autoantibodies; Depression, Postpartum; Female; Humans; Iodide Peroxidase; Prospective Studies; Thyr | 2023 |
[Postpartum depression].
Topics: Androgens; Depression, Postpartum; Diagnosis, Differential; Estradiol; Female; Humans; Hydrocortison | 2003 |
1 trial available for thyroxine and Depression, Postpartum
| Article | Year |
|---|---|
Randomised trial of thyroxine to prevent postnatal depression in thyroid-antibody-positive women.
Topics: Adolescent; Adult; Autoantibodies; Depression, Postpartum; Female; Humans; Pregnancy; Psychiatric St | 2002 |
12 other studies available for thyroxine and Depression, Postpartum
| Article | Year |
|---|---|
Neuroprotection of reduced thyroid hormone with increased estrogen and progestogen in postpartum depression.
Topics: Adult; Animals; Antithyroid Agents; Basolateral Nuclear Complex; Body Weight; Brain-Derived Neurotro | 2019 |
Increased thyroid autoimmunity among women with multiple sclerosis in the postpartum setting.
Topics: Adult; Antibodies; Case-Control Studies; Delivery, Obstetric; Depression, Postpartum; Fatigue; Femal | 2013 |
Late pregnancy thyroid-binding globulin predicts perinatal depression.
Topics: Adult; Anxiety; Depression, Postpartum; Depressive Disorder, Major; Female; Humans; Predictive Value | 2016 |
Postpartum thyroid measures and depressive symptomology: a pilot study.
Topics: Adolescent; Adult; Antibodies; Depression, Postpartum; Female; Humans; Pilot Projects; Pregnancy; Th | 2008 |
Childhood sexual abuse and hypothalamus-pituitary-thyroid axis in postpartum major depression.
Topics: Adult; Autoantibodies; Autoantigens; Child; Child Abuse, Sexual; Depression, Postpartum; Depressive | 2010 |
Thyroid function 48h after delivery as a marker for subsequent postpartum depression.
Topics: Adult; Autoantibodies; Biomarkers; Depression, Postpartum; Female; Humans; Postpartum Period; Predic | 2010 |
Early pospartum alexithymia and risk for depression: relationship with serum thyrotropin, free thyroid hormones and thyroid autoantibodies.
Topics: Adult; Affective Symptoms; Autoantibodies; Depression, Postpartum; Female; Humans; Iodide Peroxidase | 2012 |
Childhood physical abuse as a common risk factor for depression and thyroid dysfunction in the earlier postpartum.
Topics: Adult; Adult Survivors of Child Abuse; Depression, Postpartum; Female; Humans; Psychiatric Status Ra | 2012 |
Postpartum psychiatric disorders.
Topics: Depression, Postpartum; Female; Humans; Hyperthyroidism; Thyroxine | 2004 |
Neonatal effects of maternal hypothyroxinemia during early pregnancy.
Topics: Child Development; Depression, Postpartum; Developmental Disabilities; Female; Humans; Hypothyroidis | 2006 |
Antenatal thyroid correlates of postpartum depression.
Topics: Adolescent; Adult; Case-Control Studies; Depression; Depression, Postpartum; Depressive Disorder; Fe | 2007 |
Postpartum thyroid dysfunction: clinical assessment and relationship to psychiatric affective morbidity.
Topics: Adult; Case-Control Studies; Depression, Postpartum; Double-Blind Method; Female; Humans; Odds Ratio | 1999 |