thyroxine has been researched along with Depression, Endogenous in 153 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study did not achieve its planned sample size, thus our conclusions may be limited, but in this cohort of pregnant women with subclinical hypothyroidism, antenatal thyroxine replacement did not improve maternal depressive symptoms." | 9.34 | Effect of Thyroxine Therapy on Depressive Symptoms Among Women With Subclinical Hypothyroidism. ( Boggess, K; Caritis, SN; Casey, BM; Costantine, MM; Iams, JD; Mercer, BM; Peaceman, AM; Reddy, UM; Rouse, DJ; Sibai, B; Smith, K; Sorokin, Y; Thom, EA; Tita, ATN; Tolosa, JE; VanDorsten, JP; Varner, MW; Wapner, RJ, 2020) |
| "An 8-week open trial was conducted to investigate whether patients with treatment-resistant, chronic depression and/or dysthymia could profit from high-dose thyroxine (T4) augmentation." | 9.09 | Treatment of refractory chronic depression and dysthymia with high-dose thyroxine. ( Baumgartner, A; Pichler, P; Rudas, S; Schmitz, M, 1999) |
| "This study did not achieve its planned sample size, thus our conclusions may be limited, but in this cohort of pregnant women with subclinical hypothyroidism, antenatal thyroxine replacement did not improve maternal depressive symptoms." | 5.34 | Effect of Thyroxine Therapy on Depressive Symptoms Among Women With Subclinical Hypothyroidism. ( Boggess, K; Caritis, SN; Casey, BM; Costantine, MM; Iams, JD; Mercer, BM; Peaceman, AM; Reddy, UM; Rouse, DJ; Sibai, B; Smith, K; Sorokin, Y; Thom, EA; Tita, ATN; Tolosa, JE; VanDorsten, JP; Varner, MW; Wapner, RJ, 2020) |
| "While clinical hypothyroidism is associated with frank neuropsychological and affective alterations and is considered one of the causes of reversible dementia, the occurrence of these alterations and their treatment in mild hypothyroidism (MH) remains a controversial issue." | 5.32 | Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment. ( Blandini, F; Bono, G; Fancellu, R; Mauri, M; Santoro, G, 2004) |
| "Hypothyroidism is associated with both reduced central 5-HT function and an increased incidence of depression." | 5.29 | Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism. ( Chambers, SM; Cleare, AJ; Dawling, S; McGregor, A; O'Keane, V, 1996) |
| " Add-on treatment with supraphysiologic doses of levothyroxine (LT4) has shown efficacy in open-label and in placebo-controlled studies, including in rapid cycling and prophylaxis-resistant bipolar disorder, and with acute refractory uni- or bipolar depression." | 5.12 | Role of thyroid hormone therapy in depressive disorders. ( Bauer, M; Whybrow, PC, 2021) |
| "An 8-week open trial was conducted to investigate whether patients with treatment-resistant, chronic depression and/or dysthymia could profit from high-dose thyroxine (T4) augmentation." | 5.09 | Treatment of refractory chronic depression and dysthymia with high-dose thyroxine. ( Baumgartner, A; Pichler, P; Rudas, S; Schmitz, M, 1999) |
| "The authors administered 50-100 micrograms of thyroxine (T4) alone for 2 weeks to 20 patients with primary major depressive disorders, evaluated clinical changes, and compared the thyroid functions before and after the trial." | 5.06 | Thyroid function and therapeutic efficacy of thyroxine in depression. ( Nakayasu, N; Okuno, Y, 1988) |
| " Four hypotheses suggest an effect in these ailments: 1) a local relative T4 excess present (or better postulated to be present) in the brain of depressed patients is lowered by triiodothyronine (T3), by lowering serum levels of thyroxine (T4), 2) the effect of a depression-mediated cerebral lack of catecholamines is compensated by the T3/T4 induced activation of beta-receptors, 3) a postulated depression-induced local cerebral hypothyroidism can be counteracted by T3 and T4." | 4.80 | [Administration of thyroid hormones in therapy of psychiatric illnesses]. ( Weissel, M, 1999) |
| "One hundred and ninety-nine pregnant women three times during pregnancy were assessed for depressive disorder and for thyroid stimulating hormone (TSH) and free thyroxine (FT(4)) concentrations." | 3.75 | Depressive disorder and thyroid axis functioning during pregnancy. ( Bunevicius, A; Bunevicius, R; Kusminskas, L; Mickuviene, N; Pedersen, CA; Pop, VJ, 2009) |
| "We previously found significantly higher T3-resin uptake and nearly significantly lower total thyroxine concentrations at 38 weeks of pregnancy in women with higher postpartum depression ratings." | 3.74 | Antenatal thyroid correlates of postpartum depression. ( Bunevicius, R; Hamer, RM; Johnson, JL; Leserman, J; Meltzer-Brody, S; Pedersen, CA; Silva, S, 2007) |
| "The authors used a Cox regression survival analysis to evaluate the relationship between life course of depressive illness and basal levels of thyroid hormones (triiodothyronine [T(3)], thyroxine [T(4)], and thyrotropin) in 75 outpatients with unipolar major depressive disorder." | 3.70 | Thyroid hormone levels and recurrence of major depression. ( Joffe, RT; Marriott, M, 2000) |
| "To describe a patient with longstanding depression and hypothyroidism who had marked mood improvement only after triiodothyronine (T3) was added to her thyroxine (T4) replacement therapy." | 3.70 | Hypothyroidism and depression: a therapeutic challenge. ( Makela, EH; Rack, SK, 2000) |
| "Serum concentrations of thyrotropine (TSH), thyroxine (T4), free T4 (fT4), triiodothyronine (T3) and reverse T3 (rT3) were measured 4 x during a 12-month period in 28 patients with major depressive disorder maintained on lithium prophylaxis for 4-23 years (mean = 11." | 3.69 | The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: high triiodothyronine serum concentrations are correlated to the prophylactic efficacy. ( Baumgartner, A; Gräf, KJ; Kürten, I; Müller-Oerlinghausen, B; von Stuckrad, M, 1995) |
| "Medication-free inpatients with major depression or bipolar disorder were studied with oxygen-15 water and positron emission tomography (PET) to measure CBF (N = 19) or with [18F] fluorodeoxyglucose and PET to measure cerebral glucose metabolism (N = 29)." | 3.69 | Inverse relationship of peripheral thyrotropin-stimulating hormone levels to brain activity in mood disorders. ( Andreason, PJ; Callahan, AM; George, MS; Herscovitch, P; Horwitz, B; Ketter, TA; Marangell, LB; Parekh, P; Pazzaglia, PJ; Post, RM, 1997) |
| "In the present study, the levels of the baseline cortisol, thyrotropin (TSH), triiodothyronine (T3), thyroxine (T4) and growth hormone (GH) were determined in 64 depressive patients, 17 patients with other depressive disorders and 19 normal controls." | 3.68 | [The endocrine abnormalities of depressive patients]. ( Yang, Q, 1992) |
| "Thyrotropin (TSH), thyroxine (T4), free T4, triiodothyronine (T3), and free T3 (fT3) concentrations were measured in 25 patients with major depressive disorder at 8 a." | 3.68 | Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder. ( Baumgartner, A; Gräf, KJ; Kürten, I; Meinhold, H, 1990) |
| " In the present study, thyroid functions (TFTs) and thyrotropin-releasing hormone (TRH) stimulation of thyroid-stimulating hormone (TSH) were measured before and after treatment with desipramine (DMI) in 13 men with a diagnosis of major depressive disorder." | 3.67 | The thyroid axis and desipramine treatment in depression. ( Anton, RF; Brady, KT, 1989) |
| "Levels of circulating total thyroxine (TT4), free thyroxine (FT4), total triiodothyronine TT3 and thyrotropin (TSH) were determined in 27 men with unipolar major depressive disorder ages 24-50, mean +/- SEM 36." | 3.67 | Serum concentrations of circulating thyroid hormones in a group of depressed men. ( Friedenthal, S; Giller, E; Ibrahim, G; Kosten, T; Mason, J; Wahby, V, 1989) |
| "Serum free thyroxine (FT4) and total thyroxine (TT4) levels were measured at 2-week intervals during the course of hospitalization in 29 male inpatients in the following four diagnostic groups: paranoid schizophrenia (PS); undifferentiated schizophrenia; bipolar I disorder, manic; and major depressive disorder, endogenous type." | 3.67 | Serum thyroxine levels in schizophrenic and affective disorder diagnostic subgroups. ( Giller, EL; Kennedy, JL; Kosten, TR; Mason, JW, 1989) |
| "It has been suggested that adenylate cyclase inhibition may be important in the development of both nephrogenic diabetes insipidus and hypothyroidism during lithium treatment." | 3.67 | Thyroid function and urine-concentrating ability during lithium treatment. ( Waller, DG, 1985) |
| "The serum levels of thyroxine and triiodothyronine (T4 and T3) were investigated at 10 different time points during a 24 h period in 31 inpatients meeting the RDC criteria for acute major depressive disorder." | 3.67 | Twenty-four-hour serum levels of T4 and T3 in relation to decreased TSH serum levels and decreased TSH response to TRH in affective disorders. ( Beck-Friis, J; Kjellman, BF; Ljunggren, JG; Undén, F; Wetterberg, L, 1986) |
| "In an effort to explore the relationship between Grade II hypothyroidism and depressive symptoms, 16 nursing home residents with normal free thyroxine index and elevated basal thyrotropin (thyroid-stimulating hormone; TSH) levels were matched for age, sex, nursing level of care, and certain medications with a control group who had normal basal TSH levels." | 3.67 | Psychological depressive symptoms in grade II hypothyroidism in a nursing home. ( Drinka, PJ; Voeks, SK, 1987) |
| " Each of these nine patients with symptomless autoimmune thyroiditis had normal baseline serum thyrotropin concentrations and normal thyroid function (as assessed by T4, T3 uptake, and free thyroxine index)." | 3.67 | Antithyroid antibodies in depressed patients. ( Evans, DL; Haggerty, JJ; Nemeroff, CB; Simon, JS, 1985) |
| "Patients entering a depressive recurrence manifested lower free versus bound thyroxine quotients and had higher TSH secretion." | 2.66 | Thyroxine binding and TSH in recurrent depressive episodes. ( Garvey, MJ; Hoffmann, N; Tollefson, G; Tuason, VB; Valentine, R, 1985) |
| "Subclinical hypothyroidism is more common than HO and is most prevalent in the elderly, particularly in women." | 2.42 | Cognitive and neuropsychiatric aspects of subclinical hypothyroidism: significance in the elderly. ( Davis, JD; Flashman, LA; Stern, RA, 2003) |
| "The prevalence of autoimmune thyroiditis in the general population is estimated to be at about 5-14 %." | 1.42 | Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients. ( Degner, D; Haust, M; Meller, J; Reulbach, U; Rüther, E, 2015) |
| "Lifetime depressive syndrome was associated with neither TSH level nor T4 levels in men or women." | 1.33 | Lower TSH and higher T4 levels are associated with current depressive syndrome in young adults. ( Forman-Hoffman, V; Philibert, RA, 2006) |
| "While clinical hypothyroidism is associated with frank neuropsychological and affective alterations and is considered one of the causes of reversible dementia, the occurrence of these alterations and their treatment in mild hypothyroidism (MH) remains a controversial issue." | 1.32 | Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment. ( Blandini, F; Bono, G; Fancellu, R; Mauri, M; Santoro, G, 2004) |
| "Treatment with sertraline for 4 weeks increased plasma cortisol levels, while 24 weeks of sertraline treatment increased plasma T(3) levels in depressed patients." | 1.31 | Effects of sertraline treatment on plasma cortisol, prolactin and thyroid hormones in female depressed patients. ( Jakovljević, M; Korsić, M; Mihaljević-Peles, A; Mück-Seler, D; Pivac, N; Sagud, M, 2002) |
| "Hypothyroidism is associated with both reduced central 5-HT function and an increased incidence of depression." | 1.29 | Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism. ( Chambers, SM; Cleare, AJ; Dawling, S; McGregor, A; O'Keane, V, 1996) |
| "Piribedil is a relatively selective dopamine agonist with moderate antidepressant activity." | 1.27 | Neuroendocrine effects of the dopamine agonist piribedil in depressed patients. ( Ballenger, JC; Gold, PW; Joffe, RT; Post, RM; Rakita, R; Rebar, R, 1986) |
| "A 24-year-old woman with a unipolar depression had an augmented thyroid-stimulating hormone response to thyrotropin-releasing hormone (TRH), suggesting subclinical hypothyroidism." | 1.26 | Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles? ( Extein, I; Gold, MS; Pottash, AL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (37.25) | 18.7374 |
| 1990's | 58 (37.91) | 18.2507 |
| 2000's | 24 (15.69) | 29.6817 |
| 2010's | 12 (7.84) | 24.3611 |
| 2020's | 2 (1.31) | 2.80 |
| Authors | Studies |
|---|---|
| Costantine, MM | 1 |
| Smith, K | 1 |
| Thom, EA | 1 |
| Casey, BM | 1 |
| Peaceman, AM | 1 |
| Varner, MW | 1 |
| Sorokin, Y | 1 |
| Reddy, UM | 1 |
| Wapner, RJ | 1 |
| Boggess, K | 1 |
| Tita, ATN | 1 |
| Rouse, DJ | 1 |
| Sibai, B | 1 |
| Iams, JD | 1 |
| Mercer, BM | 1 |
| Tolosa, JE | 1 |
| Caritis, SN | 1 |
| VanDorsten, JP | 1 |
| Bauer, M | 3 |
| Whybrow, PC | 2 |
| Zhao, T | 1 |
| Chen, BM | 1 |
| Zhao, XM | 1 |
| Shan, ZY | 1 |
| Lee, S | 1 |
| Oh, SS | 1 |
| Park, EC | 1 |
| Jang, SI | 1 |
| Kalra, S | 1 |
| Balhara, YP | 1 |
| Fjaellegaard, K | 1 |
| Kvetny, J | 1 |
| Allerup, PN | 1 |
| Bech, P | 1 |
| Ellervik, C | 1 |
| Degner, D | 1 |
| Haust, M | 1 |
| Meller, J | 1 |
| Rüther, E | 1 |
| Reulbach, U | 1 |
| Kim, EY | 1 |
| Kim, SH | 1 |
| Rhee, SJ | 1 |
| Huh, I | 1 |
| Ha, K | 1 |
| Kim, J | 1 |
| Chang, JS | 1 |
| Yoon, DH | 1 |
| Park, T | 1 |
| Ahn, YM | 1 |
| Carney, RM | 1 |
| Freedland, KE | 1 |
| Steinmeyer, B | 1 |
| Rubin, EH | 1 |
| Mann, DL | 1 |
| Rich, MW | 1 |
| El-Hage, W | 1 |
| Montes, ML | 1 |
| Fraile, JM | 1 |
| González, JJ | 1 |
| Arribas, JR | 1 |
| Holtmann, M | 1 |
| Duketis, E | 1 |
| Goth, K | 1 |
| Poustka, L | 1 |
| Boelte, S | 1 |
| Bunevicius, R | 2 |
| Kusminskas, L | 1 |
| Mickuviene, N | 1 |
| Bunevicius, A | 1 |
| Pedersen, CA | 2 |
| Pop, VJ | 1 |
| Shukla, PK | 1 |
| Sittig, LJ | 1 |
| Andrus, BM | 1 |
| Schaffer, DJ | 1 |
| Batra, KK | 1 |
| Redei, EE | 1 |
| Duval, F | 2 |
| Mokrani, MC | 2 |
| Lopera, FG | 1 |
| Diep, TS | 2 |
| Rabia, H | 1 |
| Fattah, S | 1 |
| van de Ven, AC | 1 |
| Muntjewerff, JW | 1 |
| Netea-Maier, RT | 1 |
| de Vegt, F | 1 |
| Ross, HA | 1 |
| Sweep, FC | 1 |
| Kiemeney, LA | 1 |
| Vos, PE | 1 |
| Buitelaar, JK | 1 |
| Hermus, AR | 1 |
| den Heijer, M | 1 |
| Janzing, JG | 1 |
| LIPNER, HJ | 1 |
| WAGNER, BP | 1 |
| MORRIS, HP | 1 |
| Davis, JD | 1 |
| Stern, RA | 1 |
| Flashman, LA | 1 |
| STARR, P | 1 |
| Gendall, KA | 1 |
| Joyce, PR | 3 |
| Mulder, RT | 3 |
| Luty, SE | 1 |
| Kolawole, BA | 1 |
| Ikem, RT | 1 |
| Bahls, SC | 1 |
| de Carvalho, GA | 1 |
| Bono, G | 1 |
| Fancellu, R | 1 |
| Blandini, F | 1 |
| Santoro, G | 1 |
| Mauri, M | 1 |
| Joffe, RT | 13 |
| Sawka, AM | 1 |
| Marriott, MJ | 1 |
| MacQueen, GM | 1 |
| Gernstein, HC | 1 |
| Schüle, C | 1 |
| Baghai, TC | 1 |
| Tsikolata, V | 1 |
| Zwanzger, P | 1 |
| Eser, D | 1 |
| Schaaf, L | 1 |
| Rupprecht, R | 2 |
| Monteleone, P | 1 |
| Santonastaso, P | 1 |
| Pannuto, M | 1 |
| Favaro, A | 1 |
| Caregaro, L | 1 |
| Castaldo, E | 1 |
| Zanetti, T | 1 |
| Maj, M | 1 |
| Grajower, MM | 1 |
| Chakrabarti, K | 1 |
| Singh, PM | 1 |
| Joshi, SP | 1 |
| Forman-Hoffman, V | 1 |
| Philibert, RA | 1 |
| Roberts, LM | 1 |
| Pattison, H | 1 |
| Roalfe, A | 1 |
| Franklyn, J | 1 |
| Wilson, S | 1 |
| Hobbs, FD | 1 |
| Parle, JV | 1 |
| Johnson, JL | 1 |
| Silva, S | 1 |
| Meltzer-Brody, S | 1 |
| Hamer, RM | 1 |
| Leserman, J | 1 |
| Czekalski, S | 1 |
| Horodnicki, JM | 1 |
| Spychalska-Mauritsch, T | 1 |
| Wdowiak, J | 1 |
| Gołebiowska, I | 1 |
| Sternbach, HA | 1 |
| Gold, MS | 4 |
| Pottash, AC | 1 |
| Extein, I | 2 |
| Loosen, PT | 5 |
| Wilson, IC | 2 |
| Dew, BW | 2 |
| Tipermas, A | 1 |
| Kjellman, BF | 3 |
| Ljunggren, JG | 3 |
| Beck-Friis, J | 3 |
| Wetterberg, L | 3 |
| Targum, SD | 4 |
| Greenberg, RD | 2 |
| Harmon, RL | 2 |
| Kessler, K | 2 |
| Salerian, AJ | 2 |
| Fram, DH | 2 |
| Dackis, CA | 1 |
| Bailey, J | 1 |
| Pottash, AL | 2 |
| Stuckey, RF | 1 |
| Extein, IL | 2 |
| Schwarcz, G | 1 |
| Halaris, A | 1 |
| Baxter, L | 1 |
| Escobar, J | 1 |
| Thompson, M | 1 |
| Young, M | 1 |
| Roy-Byrne, PP | 1 |
| Uhde, TW | 2 |
| Post, RM | 8 |
| Calloway, SP | 1 |
| Dolan, RJ | 1 |
| Fonagy, P | 1 |
| De Souza, VF | 1 |
| Wakeling, A | 1 |
| Prange, AJ | 4 |
| Rais, N | 1 |
| Bhandarkar, SD | 1 |
| Vahora, S | 1 |
| Mehta, JM | 1 |
| Sullivan, AC | 2 |
| Byrnes, SM | 2 |
| Walsh, BT | 1 |
| Linnoila, M | 1 |
| Lamberg, BA | 1 |
| Potter, WZ | 1 |
| Gold, PW | 2 |
| Goodwin, FK | 2 |
| Muscettola, G | 1 |
| Lipton, MA | 1 |
| Stewart, JW | 1 |
| Weeke, A | 1 |
| Weeke, J | 1 |
| Baumgartner, A | 9 |
| von Stuckrad, M | 1 |
| Müller-Oerlinghausen, B | 1 |
| Gräf, KJ | 5 |
| Kürten, I | 4 |
| Fava, M | 2 |
| Labbate, LA | 1 |
| Abraham, ME | 1 |
| Rosenbaum, JF | 1 |
| Harel, Z | 1 |
| Biro, FM | 1 |
| Tedford, WL | 1 |
| Samson, JA | 1 |
| Mirin, SM | 1 |
| Griffin, M | 1 |
| Borrelli, D | 1 |
| Schildkraut, JJ | 1 |
| Maes, M | 7 |
| D'Hondt, P | 3 |
| Blockx, P | 5 |
| Cosyns, P | 4 |
| Priebe, S | 1 |
| Dommisse, J | 1 |
| Magliozzi, JR | 1 |
| Maddock, RJ | 1 |
| Gold, AS | 1 |
| Gietzen, DW | 1 |
| Shelton, RC | 1 |
| Winn, S | 1 |
| Ekhatore, N | 1 |
| Joffe, R | 2 |
| Segal, Z | 1 |
| Singer, W | 5 |
| Crocq, MA | 1 |
| Jautz, M | 1 |
| Bailey, P | 1 |
| Macher, JP | 1 |
| Cleare, AJ | 1 |
| McGregor, A | 1 |
| Chambers, SM | 1 |
| Dawling, S | 1 |
| O'Keane, V | 1 |
| Levitt, AJ | 4 |
| Young, LT | 1 |
| Volz, HP | 1 |
| Campos-Barros, A | 1 |
| Stieglitz, RD | 1 |
| Mansmann, U | 1 |
| Mackert, A | 1 |
| Prasher, VP | 1 |
| Hall, W | 1 |
| Marangell, LB | 2 |
| Ketter, TA | 2 |
| George, MS | 1 |
| Pazzaglia, PJ | 1 |
| Callahan, AM | 2 |
| Parekh, P | 1 |
| Andreason, PJ | 1 |
| Horwitz, B | 1 |
| Herscovitch, P | 1 |
| Woeber, KA | 1 |
| Vandoolaeghe, E | 1 |
| Vandevyvere, J | 1 |
| Neels, H | 1 |
| Sullivan, PF | 1 |
| Wilson, DA | 2 |
| Haggerty, JJ | 3 |
| Silva, SG | 1 |
| Marquardt, M | 1 |
| Mason, GA | 1 |
| Chang, HY | 1 |
| Evans, DL | 3 |
| Golden, RN | 1 |
| Pedersen, C | 1 |
| Simpson, HB | 1 |
| Hurowitz, GI | 1 |
| Liebowitz, MR | 1 |
| Motohashi, N | 1 |
| Parekh, PI | 1 |
| Altshuler, L | 1 |
| Frye, MA | 2 |
| Callahan, A | 1 |
| Marangell, L | 1 |
| Hellweg, R | 1 |
| Moreau, X | 1 |
| Azorin, JM | 1 |
| Maurel, M | 1 |
| Jeanningros, R | 1 |
| Spoov, J | 1 |
| Lahdelma, L | 1 |
| Rudas, S | 1 |
| Schmitz, M | 1 |
| Pichler, P | 1 |
| Sullivan, GM | 1 |
| Hatterer, JA | 2 |
| Herbert, J | 1 |
| Chen, X | 1 |
| Roose, SP | 1 |
| Attia, E | 1 |
| Mann, JJ | 1 |
| Goetz, RR | 1 |
| Gorman, JM | 2 |
| Dunn, RT | 1 |
| Gary, KA | 1 |
| Kimbrell, TA | 1 |
| Luckenbaugh, DA | 1 |
| Corá-Locatelli, G | 1 |
| Vanderham, E | 1 |
| Winokur, A | 1 |
| Weissel, M | 1 |
| Marriott, M | 1 |
| Rack, SK | 1 |
| Makela, EH | 1 |
| Dhar, HL | 1 |
| Vasanti, T | 1 |
| Sagud, M | 1 |
| Pivac, N | 1 |
| Mück-Seler, D | 1 |
| Jakovljević, M | 1 |
| Mihaljević-Peles, A | 1 |
| Korsić, M | 1 |
| Foltyn, W | 1 |
| Nowakowska-Zajdel, E | 1 |
| Danikiewicz, A | 1 |
| Brodziak, A | 1 |
| Weetman, AP | 1 |
| Southmayd, SE | 1 |
| Kasurak, P | 1 |
| MacDonald, B | 1 |
| Waldron, J | 1 |
| Maes, L | 2 |
| Schotte, C | 5 |
| Yang, Q | 1 |
| Bagby, RM | 1 |
| Szuba, MP | 1 |
| Altshuler, LL | 1 |
| Baxter, LR | 1 |
| Cooke, RG | 2 |
| Kirkegaard, C | 3 |
| Faber, J | 3 |
| Styra, R | 1 |
| Meinhold, H | 3 |
| Willenbring, ML | 1 |
| Anton, RF | 2 |
| Spring, WD | 1 |
| Shafer, RB | 1 |
| Dorus, W | 1 |
| Kramlinger, KG | 1 |
| Roca, RP | 1 |
| Blackman, MR | 1 |
| Ackerley, MB | 1 |
| Harman, SM | 1 |
| Gregerman, RI | 1 |
| Vandewoude, M | 4 |
| Martin, M | 4 |
| Chen, CJ | 1 |
| Sikes, CR | 1 |
| Dziewanowska, ZE | 1 |
| Stokes, PE | 1 |
| Carstens, ME | 1 |
| Taljaard, JJ | 1 |
| van Zyl, AM | 1 |
| Scharpé, S | 3 |
| Denicoff, KD | 1 |
| Lakshmanan, MC | 1 |
| Robbins, J | 1 |
| Rubinow, DR | 1 |
| Kørner, A | 1 |
| Scott, AI | 1 |
| Milner, JB | 1 |
| Shering, PA | 1 |
| Beckett, GJ | 1 |
| Brady, KT | 1 |
| Gillette, GM | 1 |
| Garbutt, JC | 1 |
| Quade, DE | 1 |
| Clower, CG | 1 |
| Wahby, V | 1 |
| Ibrahim, G | 1 |
| Friedenthal, S | 1 |
| Giller, E | 1 |
| Kosten, T | 1 |
| Mason, J | 1 |
| Kitamura, T | 1 |
| Kano, S | 1 |
| Shima, S | 1 |
| Asai, M | 1 |
| Mason, JW | 3 |
| Kennedy, JL | 1 |
| Kosten, TR | 2 |
| Giller, EL | 3 |
| Wang, SY | 1 |
| Shin, SJ | 1 |
| Rupprecht, C | 1 |
| Rupprecht, M | 1 |
| Noder, M | 1 |
| Mahlstedt, J | 1 |
| Southwick, S | 1 |
| Waller, DG | 1 |
| Undén, F | 2 |
| Okuno, Y | 1 |
| Nakayasu, N | 1 |
| Marciniak, R | 1 |
| Thadani, K | 1 |
| Rubin, RT | 1 |
| Poland, RE | 1 |
| Lesser, IM | 1 |
| Martin, DJ | 1 |
| Müller, B | 1 |
| Böning, J | 1 |
| Wahby, VS | 1 |
| Ibrahim, GA | 1 |
| Martin, RP | 1 |
| Saddik, FW | 1 |
| Singh, SP | 1 |
| Gewirtz, GR | 1 |
| Malaspina, D | 1 |
| Feureisen, S | 1 |
| Klein, D | 1 |
| McNamara, ME | 1 |
| Southwick, SM | 1 |
| Fogel, BS | 1 |
| Drinka, PJ | 1 |
| Voeks, SK | 1 |
| Thomas, DR | 1 |
| Ross, SB | 1 |
| Ballenger, JC | 1 |
| Rebar, R | 1 |
| Rakita, R | 1 |
| Tollefson, G | 1 |
| Valentine, R | 1 |
| Hoffmann, N | 1 |
| Garvey, MJ | 1 |
| Tuason, VB | 1 |
| Orsulak, PJ | 1 |
| Crowley, G | 1 |
| Schlesser, MA | 1 |
| Giles, D | 1 |
| Fairchild, C | 1 |
| Rush, AJ | 1 |
| Nemeroff, CB | 1 |
| Simon, JS | 1 |
| Blank, DW | 1 |
| Berrios, GE | 1 |
| Leysen, A | 1 |
| Samuel, C | 1 |
| Dowson, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) a Multicentre Open-label Randomized Controlled Trial Protocol[NCT05814640] | Phase 1/Phase 2 | 520 participants (Anticipated) | Interventional | 2023-02-20 | Recruiting | ||
| Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers[NCT03638687] | 80 participants (Anticipated) | Observational | 2014-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for thyroxine and Depression, Endogenous
| Article | Year |
|---|---|
Role of thyroid hormone therapy in depressive disorders.
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Drug Interactions; Humans; Thyroid Dis | 2021 |
Subclinical hypothyroidism and depression: a meta-analysis.
Topics: Adult; Aged; Comorbidity; Depression; Depressive Disorder; Humans; Hypothyroidism; Middle Aged; Thyr | 2018 |
Euthyroid depression: the role of thyroid hormone.
Topics: Antidepressive Agents; Brain; Depressive Disorder; Drug Therapy, Combination; Humans; Patents as Top | 2014 |
Cognitive and neuropsychiatric aspects of subclinical hypothyroidism: significance in the elderly.
Topics: Aged; Clinical Trials as Topic; Cognition Disorders; Dementia; Depressive Disorder; Humans; Hypothal | 2003 |
[The relation between thyroid function and depression: a review].
Topics: Biogenic Monoamines; Brain; Depressive Disorder; Humans; Hypothalamo-Hypophyseal System; Pituitary-A | 2004 |
[Serum thyrotropin, thyroxine, 3,3',5-triiodothyronine and 3,3',5'-triiodothyronine concentrations in patients with endogenous depression].
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Female; Humans; Male; Middle Aged; Thy | 1983 |
The therapeutic use of triiodothyronine and high dose thyroxine in psychiatric disorder.
Topics: Bipolar Disorder; Brain; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combin | 1994 |
Subclinical thyroid dysfunction.
Topics: Atrial Fibrillation; Bone Density; Depressive Disorder; Female; Humans; Hypothyroidism; Lipids; Male | 1997 |
[Background and therapy of intractable depression].
Topics: Adult; Antidepressive Agents; Depressive Disorder; Dopamine Agents; Electroconvulsive Therapy; Human | 1997 |
The use of thyroid supplements to augment antidepressant medication.
Topics: Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Drug Adminis | 1998 |
[Administration of thyroid hormones in therapy of psychiatric illnesses].
Topics: Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Humans; Hypothyroidism; Thyro | 1999 |
New approaches to the treatment of refractory depression.
Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; M | 2000 |
[Hypothalamic-pituitary-thyroid axis in depression].
Topics: Depressive Disorder; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Pituitary-Adrenal Syste | 2002 |
Thyroxine treatment in biochemically euthyroid but clinically hypothyroid individuals.
Topics: Depressive Disorder; Diagnosis, Differential; Fatigue Syndrome, Chronic; Humans; Hypothyroidism; Mid | 2002 |
Thyroid hormone potentiation of tricyclics.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Synergism; Humans; Hypothyroidism; Lithi | 1988 |
The hypothalamic-pituitary-thyroid axis in psychiatric patients and healthy subjects: Parts 1-4.
Topics: Adolescent; Adult; Aged; Arousal; Depressive Disorder; Female; Humans; Male; Middle Aged; Prognosis; | 1988 |
18 trials available for thyroxine and Depression, Endogenous
| Article | Year |
|---|---|
Effect of Thyroxine Therapy on Depressive Symptoms Among Women With Subclinical Hypothyroidism.
Topics: Adult; Cohort Studies; Depressive Disorder; Female; Humans; Hypothyroidism; Pregnancy; Pregnancy Com | 2020 |
Cardiac Risk Markers and Response to Depression Treatment in Patients With Coronary Heart Disease.
Topics: Antidepressive Agents; Biomarkers; C-Reactive Protein; Causality; Cognitive Behavioral Therapy; Comb | 2016 |
Thyroid indices and response to fluoxetine and nortriptyline in major depression.
Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder; Female; Fluoxetine; Humans; Male; Mid | 2003 |
Does substitution of T4 with T3 plus T4 for T4 replacement improve depressive symptoms in patients with hypothyroidism?
Topics: Adult; Aged; Depressive Disorder; Drug Therapy, Combination; Female; Hormone Replacement Therapy; Hu | 2004 |
The combined T3/TRH test in depressed patients and healthy controls.
Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Drug Interactions; Female; Heart Rate; Hormones; H | 2005 |
Hypothyroidism and hyperthyroidism in major depression revisited.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Depressive Disorder; Female; Fluoxetine; Humans; Hyperthyr | 1995 |
Effect of antidepressant medication on morning and evening thyroid function tests during a major depressive episode.
Topics: Adult; Antidepressive Agents; Circadian Rhythm; Depressive Disorder; Female; Hospitalization; Humans | 1996 |
The thyroid, magnesium and calcium in major depression.
Topics: Adult; Calcium; Depressive Disorder; Female; Humans; Magnesium; Male; Psychiatric Status Rating Scal | 1996 |
Serum concentrations of thyroid hormones in patients with nonseasonal affective disorders during treatment with bright and dim light.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Personality Inventory; Photothe | 1996 |
Relationships between thyroid hormone and antidepressant responses to total sleep deprivation in mood disorder patients.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Mood Disorders; Psychiatric Status Rating Scales; | 1998 |
Treatment of refractory depression with high-dose thyroxine.
Topics: Aged; Depressive Disorder; Drug Resistance; Female; Humans; Male; Middle Aged; Psychiatric Status Ra | 1998 |
Treatment of refractory chronic depression and dysthymia with high-dose thyroxine.
Topics: Adult; Aged; Antidepressive Agents; Chronic Disease; Depressive Disorder; Dose-Response Relationship | 1999 |
Lack of correlation between cerebrospinal fluid thyrotropin-releasing hormone (TRH) and TRH-stimulated thyroid-stimulating hormone in patients with depression.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Humans; Hydrocortisone; M | 1999 |
Antidepressants and thyroid hormone levels.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Thyroid Hormones; Thyrotropin; | 1992 |
Addition of lithium carbonate to carbamazepine: hematological and thyroid effects.
Topics: Adult; Blood Cell Count; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Double-Blind | 1990 |
A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants.
Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combinat | 1990 |
Thyroid function and therapeutic efficacy of thyroxine in depression.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; | 1988 |
Thyroxine binding and TSH in recurrent depressive episodes.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Double | 1985 |
119 other studies available for thyroxine and Depression, Endogenous
| Article | Year |
|---|---|
Sex differences in the association between thyroid-stimulating hormone levels and depressive symptoms among the general population with normal free T4 levels.
Topics: Adult; Aged; Aged, 80 and over; Autoimmunity; Cross-Sectional Studies; Depressive Disorder; Female; | 2019 |
Well-being and depression in individuals with subclinical hypothyroidism and thyroid autoimmunity - a general population study.
Topics: Adult; Autoantibodies; Autoimmunity; Biomarkers; Denmark; Depression; Depressive Disorder; Female; H | 2015 |
Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients.
Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Bipolar Disorder; Depressive Disorder; Female; Human | 2015 |
Relationship between thyroid-stimulating hormone levels and risk of depression among the general population with normal free T4 levels.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder; Female; Humans; Male; Middle Aged; | 2015 |
[Roadmap for therapeutic strategies of treatment resistant depression].
Topics: Antidepressive Agents; Antipsychotic Agents; Combined Modality Therapy; Depressive Disorder; Disease | 2016 |
[Chorea during treatment with pegylated interferon and ribavirin in HIV-HCV coinfected patient].
Topics: Adult; Anti-HIV Agents; Antidepressive Agents; Antiviral Agents; Anxiety Disorders; Chorea; Citalopr | 2009 |
Severe affective and behavioral dysregulation in youth is associated with increased serum TSH.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Anxiety Disorders; Attention Deficit Disord | 2010 |
Depressive disorder and thyroid axis functioning during pregnancy.
Topics: Adult; Cross-Sectional Studies; Depressive Disorder; Female; Gestational Age; Humans; Hyperthyroidis | 2009 |
Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.
Topics: Amygdala; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Depressive Disorder; Di | 2010 |
Thyroid axis activity and suicidal behavior in depressed patients.
Topics: Adult; Depressive Disorder; Female; Humans; Hypothalamus; Male; Middle Aged; Pituitary Gland; Suicid | 2010 |
Association between thyroid function, thyroid autoimmunity, and state and trait factors of depression.
Topics: Adult; Aged; Aged, 80 and over; Anxiety Disorders; Autoantibodies; Autoimmunity; Biomarkers; Cross-S | 2012 |
Thyroxine depression of mouse thyroid iodide trap activity.
Topics: Depression; Depressive Disorder; Iodides; Thyroid Gland; Thyroxine; Viscera | 1954 |
Depression of the serum cholesterol level in myxedematous patients by an oral dosage of sodium dextro-thyroxine which has no effct on the basal metabolic rate or electrocardiogram.
Topics: Basal Metabolism; Cholesterol; Depression; Depressive Disorder; Electrocardiography; Humans; Myxedem | 1960 |
A study of psychiatric symptoms in thyrotoxic Nigerians.
Topics: Adult; Affective Symptoms; Anxiety Disorders; Case-Control Studies; Cross-Sectional Studies; Depress | 2003 |
Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment.
Topics: Adult; Age Factors; Aged; Attention; Cognition Disorders; Depressive Disorder; Female; Homeostasis; | 2004 |
Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables.
Topics: Adult; Anorexia Nervosa; Blood Glucose; Borderline Personality Disorder; Bulimia; Cholesterol; Comor | 2005 |
[Thyroid diseases in the elderly].
Topics: Age Factors; Aged; Alzheimer Disease; Depressive Disorder; Humans; Hyperthyroidism; Hypothyroidism; | 2005 |
Medical management of depression.
Topics: Algorithms; Antidepressive Agents; Depressive Disorder; Humans; Thyroxine; Triiodothyronine | 2006 |
Thyroid function in depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Female; Ho | 2006 |
Lower TSH and higher T4 levels are associated with current depressive syndrome in young adults.
Topics: Adolescent; Adult; Cross-Sectional Studies; Demography; Depressive Disorder; Female; Humans; Male; S | 2006 |
Summaries for patients. Mild thyroid dysfunction is not associated with anxiety, depression, or cognition in the elderly.
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Cognition Disorders; Cross-Sectional Studies; Depressive | 2006 |
Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction?
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Cognition Disorders; Cross-Sectional Studies; Depressive | 2006 |
Antenatal thyroid correlates of postpartum depression.
Topics: Adolescent; Adult; Case-Control Studies; Depression; Depression, Postpartum; Depressive Disorder; Fe | 2007 |
Thyroid failure and protirelin (thyrotropin-releasing hormone) test abnormalities in depressed outpatients.
Topics: Adolescent; Adult; Cachexia; Depressive Disorder; Female; Humans; Hypothyroidism; Male; Middle Aged; | 1983 |
Thyrotropin-releasing hormone (TRH) in abstinent alcoholic men.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Depressive Disorder; Growth Hormone; Humans; Male; Middle | 1983 |
Reverse T3 levels in affective disorders.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; M | 1983 |
The TRH test and thyroid hormone in refractory depression.
Topics: Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Thyrotr | 1984 |
Specificity of the DST and the TRH test for major depression in alcoholics.
Topics: Adult; Alcoholism; Depressive Disorder; Dexamethasone; Ethanol; Female; Humans; Hydrocortisone; Male | 1984 |
Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.
Topics: Adult; Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Female; Humans; | 1984 |
Carbamazepine and thyroid function in affectively ill patients. Clinical and theoretical implications.
Topics: Adult; Carbamazepine; Depressive Disorder; Female; Humans; Male; Middle Aged; Radioimmunoassay; Thyr | 1984 |
Endocrine changes and clinical profiles in depression: II. The thyrotropin-releasing hormone test.
Topics: Adult; Depressive Disorder; Humans; Psychological Tests; Thyrotropin; Thyrotropin-Releasing Hormone; | 1984 |
Endocrine and behavioral changes in depression after thyrotropin-releasing hormone (TRH). Alteration by pretreatment with thyroid hormones.
Topics: Adult; Behavior; Depressive Disorder; Female; Humans; Middle Aged; Self-Assessment; Thyroid Hormones | 1980 |
Thyroxine-induced depressive psychoses (a case report).
Topics: Adult; Depressive Disorder; Female; Humans; Psychoses, Substance-Induced; Thyroxine | 1983 |
Thyroid hormone and the TRH stimulation test in refractory depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Hypoth | 1984 |
Compensatory pituitary-thyroid mechanisms in major depressive disorder.
Topics: Adolescent; Adult; Depressive Disorder; Female; Humans; Hydrocortisone; Male; Middle Aged; Prolactin | 1982 |
Neuroendocrine interrelationships in major depressive disorder.
Topics: Adolescent; Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hypothalamo-H | 1982 |
Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles?
Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Hypothyroidism; Lithium; | 1982 |
Endocrine disturbances in anorexia nervosa and depression.
Topics: Anorexia Nervosa; Depressive Disorder; Dexamethasone; Hormones; Humans; Hydrocortisone; Thyrotropin; | 1982 |
High reverse T3 levels in manic an unipolar depressed women.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Female; Humans; Thyrox | 1982 |
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Dis | 1982 |
Thyroid stimulating hormone and depression.
Topics: Depressive Disorder; Female; Humans; Thyrotropin; Thyroxine; Triiodothyronine | 1982 |
The 24-hour pattern of serum TSH in patients with endogenous depression.
Topics: Adult; Aged; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Middle A | 1980 |
The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: high triiodothyronine serum concentrations are correlated to the prophylactic efficacy.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Depressive Disorder; Female; Humans; Hypothalamo-H | 1995 |
Effects of long term treatment with sertraline (Zoloft) simulating hypothyroidism in an adolescent.
Topics: 1-Naphthylamine; Adolescent; Antidepressive Agents; Depressive Disorder; Diagnosis, Differential; Hu | 1995 |
Urinary MHPG and clinical symptoms in patients with unipolar depression.
Topics: Adult; Body Weight; Cognition Disorders; Depressive Disorder; Dexamethasone; Female; Humans; Hydroco | 1994 |
A further investigation of basal HPT axis function in unipolar depression: effects of diagnosis, hospitalization, and dexamethasone administration.
Topics: Adrenocorticotropic Hormone; Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortiso | 1994 |
Psychological and endocrine abnormalities in refugees from East Germany: Part I. Prolonged stress, psychopathology, and hypothalamic-pituitary-thyroid axis activity.
Topics: Adjustment Disorders; Anxiety Disorders; Depressive Disorder; Germany; Germany, East; Humans; Hypoth | 1994 |
T3 is at least as important as T4 in all hypothyroid patients.
Topics: Antidepressive Agents; Depressive Disorder; Drug Therapy, Combination; Humans; Hypothyroidism; Thyro | 1993 |
Relationships between thyroid indices and symptoms of anxiety in depressed outpatients.
Topics: Adult; Agoraphobia; Ambulatory Care; Anxiety Disorders; Comorbidity; Depressive Disorder; Female; Hu | 1993 |
The effects of antidepressants on the thyroid axis in depression.
Topics: Ambulatory Care; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans | 1993 |
Change in thyroid hormone levels following response to cognitive therapy for major depression.
Topics: Adult; Ambulatory Care; Cognitive Behavioral Therapy; Depressive Disorder; Female; Humans; Male; Thy | 1996 |
Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism.
Topics: Adult; Depressive Disorder; Female; Fenfluramine; Humans; Hypothyroidism; Male; Middle Aged; Prognos | 1996 |
Short-term prognosis of depression in adults with Down's syndrome: association with thyroid status and effects on adaptive behaviour.
Topics: Adolescent; Adult; Age of Onset; Amino Acids; Depressive Disorder; Down Syndrome; Female; Humans; Hy | 1996 |
Inverse relationship of peripheral thyrotropin-stimulating hormone levels to brain activity in mood disorders.
Topics: Adult; Bipolar Disorder; Brain; Cerebrovascular Circulation; Deoxyglucose; Depressive Disorder; Fema | 1997 |
Hypothalamic-pituitary-thyroid-axis function in treatment resistant depression.
Topics: Adult; Depressive Disorder; Female; Humans; Hypothalamo-Hypophyseal System; Male; Middle Aged; Thyro | 1997 |
The hypothalamic-pituitary-thyroid axis in major depression.
Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents; Case-Control Studies; Chi-Square Dis | 1997 |
Prevalence of antithyroid antibodies in mood disorders.
Topics: Adult; Age Distribution; Analysis of Variance; Antibodies; Biomarkers; Bipolar Disorder; Case-Contro | 1997 |
General principles in the pharmacotherapy of antidepressant-induced rapid cycling: a case series.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Female; Follow-Up Studies | 1997 |
Increase in red blood cell triiodothyronine uptake in untreated unipolar major depressed patients compared to healthy volunteers.
Topics: Adult; Aged; Biological Transport; Depressive Disorder; Erythrocytes; Female; Humans; Male; Middle A | 1998 |
Should thyroid augmentation precede lithium augmentation--a pilot study.
Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder; Drug Administration Schedule; Drug Sy | 1998 |
Low levels of transthyretin in the CSF of depressed patients.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Blood-Brain Barrier; Central Nervous System; Depressi | 1999 |
Thyroid hormone levels and recurrence of major depression.
Topics: Adult; Ambulatory Care; Depressive Disorder; Female; Humans; Male; Recurrence; Survival Analysis; Th | 2000 |
Hypothyroidism and depression: a therapeutic challenge.
Topics: Antidepressive Agents; Depressive Disorder; Female; Hormone Replacement Therapy; Humans; Hypothyroid | 2000 |
Endogenous depression, thyroid function and acupuncture.
Topics: Acupuncture Therapy; Adolescent; Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Thyr | 2001 |
Effects of sertraline treatment on plasma cortisol, prolactin and thyroid hormones in female depressed patients.
Topics: Antidepressive Agents; Case-Control Studies; Depressive Disorder; Female; Humans; Hydrocortisone; Mi | 2002 |
Methimazole in treatment-resistant depression.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Methimazole; Middle Aged; Personality Inventory; T | 1992 |
Therapeutic sleep deprivation in a depressed patient: prolongation of response with concurrent thyroxine.
Topics: Antidepressive Agents; Combined Modality Therapy; Depressive Disorder; Female; Humans; Middle Aged; | 1992 |
A clinical and biological validation of the DSM-III melancholia diagnosis in men: results of pattern recognition methods.
Topics: Adult; Affective Disorders, Psychotic; Amino Acids; Cluster Analysis; Depressive Disorder; Dexametha | 1992 |
[The endocrine abnormalities of depressive patients].
Topics: Adolescent; Adult; Depressive Disorder; Female; Growth Hormone; Humans; Hydrocortisone; Hypothalamo- | 1992 |
Diurnal profiles of thyroid hormones are altered in depression.
Topics: Adolescent; Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Mi | 1992 |
The thyroid and melancholia.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Neurocognitive Disorders; Psychiatric Status Ratin | 1992 |
Thyroid function and partial sleep deprivation response.
Topics: Adolescent; Adult; Aged; Arousal; Depressive Disorder; Female; Humans; Male; Middle Aged; Sleep Depr | 1992 |
T3 augmentation of antidepressant treatment in T4-replaced thyroid patients.
Topics: Antidepressive Agents; Depressive Disorder; Drug Synergism; Drug Therapy, Combination; Humans; Hypot | 1992 |
Free thyroxine and 3,3',5'-triiodothyronine levels in cerebrospinal fluid in patients with endogenous depression.
Topics: Aged; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Hyperthyroidism; Hypothyroidis | 1991 |
Hyperthyroxinemia in major affective disorders.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Female; Humans; Hyperthyroxinem | 1991 |
Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder.
Topics: Adult; Aged; Arousal; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Slee | 1990 |
Thyrotropin and prolactin response to thyrotropin-releasing hormone in depressed and nondepressed alcoholic men.
Topics: Adult; Alcoholism; Depressive Disorder; Humans; Male; Middle Aged; Personality Tests; Prolactin; Thy | 1990 |
Long-term predictors of outcome in abstinent alcoholic men.
Topics: Adult; Aged; Alcoholism; Comorbidity; Depressive Disorder; Follow-Up Studies; Growth Hormone; Humans | 1990 |
Thyroid hormone elevations during acute psychiatric illness: relationship to severity and distinction from hyperthyroidism.
Topics: Adult; Bipolar Disorder; Blood Pressure; Depressive Disorder; Down-Regulation; Feedback; Female; Hal | 1990 |
Suppressive effects of dexamethasone on hypothalamic-pituitary-thyroid axis function in depressed patients.
Topics: Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Thyroid | 1990 |
The influence of blood chemistry on T4 and FT4I in major depression.
Topics: Chlorides; Depressive Disorder; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Serum A | 1990 |
The beta-adrenoceptor and endocrine abnormalities in juvenile depression.
Topics: Adolescent; Binding Sites; Child; Depressive Disorder; Humans; Hydrocortisone; Lymphocytes; Receptor | 1990 |
Clinical subtypes of unipolar depression: Part III. Quantitative differences in various biological markers between the cluster-analytically generated nonvital and vital depression classes.
Topics: Adrenocorticotropic Hormone; Adult; Biomarkers; Depressive Disorder; Dexamethasone; Female; Humans; | 1990 |
The decreased availability of L-tryptophan in depressed females: clinical and biological correlates.
Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Analysis of Variance; Depression; Depressive Disord | 1990 |
Neuropsychiatric manifestations of altered thyroid state.
Topics: Adult; Affect; Attitude to Health; Cognition; Depressive Disorder; Female; Humans; Male; Mental Diso | 1990 |
T3 augmentation of a tricyclic antidepressant in a patient receiving T4 maintenance therapy.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Synergism; Female; Humans; Thyrox | 1990 |
Increased production of thyroxine and inappropriately elevated serum thyrotropin in levels in endogenous depression.
Topics: Adult; Aged; Aged, 80 and over; Depressive Disorder; Female; Humans; Hypothyroidism; Male; Middle Ag | 1990 |
Fall in free thyroxine after ECT: real effect or an artefact of assay?
Topics: Depressive Disorder; Electroconvulsive Therapy; Fatty Acids, Nonesterified; Female; Humans; Male; Mi | 1990 |
The thyroid axis and desipramine treatment in depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psycholo | 1989 |
TSH response to TRH in depression with and without panic attacks.
Topics: Adult; Depressive Disorder; Fear; Female; Humans; Hydrocortisone; Male; Panic; Recurrence; Sex Facto | 1989 |
The value of TSH in affective disorders.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Drug Combination | 1989 |
Hypothalamic-pituitary-adrenal and -thyroid axis dysfunctions and decrements in the availability of L-tryptophan as biological markers of suicidal ideation in major depressed females.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Amino Acids; Biomarkers; Depressive Disorder; Dexamethason | 1989 |
Serum concentrations of circulating thyroid hormones in a group of depressed men.
Topics: Adult; Depressive Disorder; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thyroid Hor | 1989 |
Hormonal changes in major depressive disorder.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; M | 1989 |
Serum thyroxine levels in schizophrenic and affective disorder diagnostic subgroups.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Diagnosis, Differential; Humans; Male; Middle Aged; Mo | 1989 |
Alterations in thyroid function tests in major depression.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Thyroid Gland; Thyroxine; Triiodothyr | 1989 |
Occult thyroid dysfunction in refractory depression.
Topics: Aged; Aged, 80 and over; Basal Metabolism; Depressive Disorder; Female; Humans; Male; Research Desig | 1989 |
Triiodothyronine, thyroxine, and TSH response to dexamethasone in depressed patients and normal controls.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Fo | 1989 |
Serum thyroxine change and clinical recovery in psychiatric inpatients.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder; Follow-Up Studies; Humans; Longitudi | 1989 |
Thyroid function and urine-concentrating ability during lithium treatment.
Topics: Cyclic AMP; Depressive Disorder; Diabetes Insipidus; Humans; Hypothyroidism; Kidney Concentrating Ab | 1985 |
Twenty-four-hour serum levels of T4 and T3 in relation to decreased TSH serum levels and decreased TSH response to TRH in affective disorders.
Topics: Adult; Body Weight; Depressive Disorder; Female; Humans; Male; Middle Aged; Receptors, Cell Surface; | 1986 |
Central thyroid stimulation in severely ill depressed, manic and schizophrenic patients.
Topics: Bipolar Disorder; Depressive Disorder; Dexamethasone; Humans; Pituitary Gland, Anterior; Schizophren | 1986 |
Influence of free thyroid hormone levels on the TSH response to TRH in endogenous depression.
Topics: Aged; Depressive Disorder; Electroshock; Female; Humans; Male; Middle Aged; Thyroid Hormones; Thyrot | 1986 |
TRH-induced TSH response in healthy volunteers: relationship to psychiatric history.
Topics: Adult; Alcoholism; Depressive Disorder; Female; Humans; Male; Sex Factors; Thyrotropin; Thyrotropin- | 1987 |
Neuroendocrine aspects of primary endogenous depression--IV. Pituitary-thyroid axis activity in patients and matched control subjects.
Topics: Adult; Aged; Body Weight; Depressive Disorder; Female; Humans; Hydrocortisone; Male; Middle Aged; Pi | 1987 |
Changes in the pituitary-thyroid axis accompanying major affective disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Bipolar Disorder; De | 1988 |
Relationship of age to TSH response to TRH in depressed men.
Topics: Adult; Aged; Cross-Sectional Studies; Depressive Disorder; Humans; Male; Middle Aged; Thyrotropin; T | 1988 |
Occult thyroid dysfunction in patients with refractory depression.
Topics: Adult; Basal Metabolism; Depressive Disorder; Female; Humans; Hypothyroidism; Middle Aged; Thyroid G | 1988 |
Sleep apnea and hypothyroidism presenting as depression in two patients.
Topics: Aged; Depressive Disorder; Diagnosis, Differential; Humans; Hypothyroidism; Male; Middle Aged; Sleep | 1987 |
Psychological depressive symptoms in grade II hypothyroidism in a nursing home.
Topics: Aged; Aged, 80 and over; Depressive Disorder; Female; Homes for the Aged; Humans; Hypothyroidism; Ma | 1987 |
T3 and T4 in unipolar depression.
Topics: Body Weight; Depressive Disorder; Humans; Thyroxine; Triiodothyronine | 1986 |
Serum dopamine-beta-hydroxylase activity in patients with major depressive disorders.
Topics: Adult; Depressive Disorder; Dopamine beta-Hydroxylase; Female; Humans; Hypothalamo-Hypophyseal Syste | 1986 |
Organic brain syndrome associated with marginal hypothyroidism.
Topics: Aged; Depressive Disorder; Female; Humans; Hypothyroidism; Male; Middle Aged; Neurocognitive Disorde | 1986 |
Neuroendocrine effects of the dopamine agonist piribedil in depressed patients.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperazines; Piribe | 1986 |
Sleep deprivation and thyroid hormone concentrations.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Sleep Deprivation; Thyrotropin; | 1986 |
Free triiodothyronine (T3) and thyroxine (T4) in a group of unipolar depressed patients and normal subjects.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Radioimmunoassay; T | 1985 |
Antithyroid antibodies in depressed patients.
Topics: Adolescent; Adult; Aged; Autoantibodies; Autoimmune Diseases; Depressive Disorder; Dexamethasone; Fe | 1985 |
Decreased triiodothyronines in depression: a preliminary report.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Thyroxine; Triiodothyronine | 1985 |
Psychiatric morbidity following total and partial thyroidectomy.
Topics: Adult; Alkaline Phosphatase; Calcium; Depressive Disorder; Female; Humans; Male; Mental Disorders; M | 1985 |