Page last updated: 2024-11-06

thyroxine and Debility

thyroxine has been researched along with Debility in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigate the relationships between free thyroxine (FT4), brain frailty and clock drawing test (CDT) performance in patients with acute minor stroke or transient ischaemic attack (TIA)."8.12Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack. ( Cao, Y; Guo, Z; Hou, J; Huang, Z; Liu, CF; Wang, H; Wang, R; Xiao, G; Xu, G; Xu, J; You, S; Yu, S, 2022)
" In this study, we investigate the relationships between free thyroxine (FT4), brain frailty and clock drawing test (CDT) performance in patients with acute minor stroke or transient ischaemic attack (TIA)."4.12Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack. ( Cao, Y; Guo, Z; Hou, J; Huang, Z; Liu, CF; Wang, H; Wang, R; Xiao, G; Xu, G; Xu, J; You, S; Yu, S, 2022)
"Frailty is a prevalent complication predicting morbidity and mortality in cirrhosis."1.72Low free triiodothyronine levels are associated with frail phenotype in hospitalized inpatients with cirrhosis. ( Fan, X; Guo, G; Hui, Y; Li, C; Li, Y; Sun, C; Sun, M; Wang, B; Wang, X; Yang, W; Yu, Z; Zhang, J; Zhao, C, 2022)
"The association between fT4 and frailty was absent in our observational study."1.72Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study. ( Cao, J; Fan, L; Guan, B; Huang, X; Liu, R; Luo, J; Ma, Y; Sun, S; Tian, F; Yu, Y, 2022)
"In particular, the Frailty Index (FI), based on the assumption that health deficits tend to accumulate with aging, represents a quantitative measure of extreme interest."1.56Thyroid hormones and frailty in persons experiencing extreme longevity. ( Arosio, B; Cesari, M; De Rango, F; Ferri, E; Franceschi, C; Mari, D; Monti, D; Ostan, R; Passarino, G; Vitale, G, 2020)
"A higher frailty index indicated a worse health state."1.48High Circulating Free Thyroxine Levels May Increase the Risk of Frailty: The Rotterdam Study. ( Bano, A; Chaker, L; Franco, OH; Ikram, MA; Kavousi, M; Mattace-Raso, FUS; Peeters, RP; Schoufour, J, 2018)
"Frailty is associated with a functional decline of multiple physiological systems, of which they may be a cause or consequence."1.46Low FT3: a possible marker of frailty in the elderly. ( Bertoli, A; Cianfarani, MA; Federici, M; Gasbarra, E; Tarantino, U; Valentini, A, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Li, C1
Zhao, C1
Yu, Z1
Yang, W1
Sun, M1
Li, Y1
Guo, G1
Hui, Y1
Wang, X1
Fan, X1
Wang, B1
Zhang, J1
Sun, C1
Guan, B3
Luo, J3
Huang, X3
Tian, F3
Sun, S3
Ma, Y3
Yu, Y3
Liu, R3
Cao, J3
Fan, L3
Arosio, B1
Monti, D1
Mari, D1
Passarino, G1
Ostan, R1
Ferri, E1
De Rango, F1
Franceschi, C1
Cesari, M1
Vitale, G1
Xiu, S1
Mu, Z1
Zhao, L1
Sun, L1
Guo, Z1
Xu, G1
Wang, R1
Hou, J1
Yu, S2
Wang, H1
Xu, J1
You, S1
Huang, Z1
Xiao, G1
Cao, Y1
Liu, CF1
Bano, A1
Chaker, L1
Schoufour, J1
Ikram, MA1
Kavousi, M1
Franco, OH1
Peeters, RP1
Mattace-Raso, FUS1
Pasqualetti, G1
Calsolaro, V1
Bernardini, S1
Linsalata, G1
Bigazzi, R1
Caraccio, N1
Monzani, F1
Bertoli, A1
Valentini, A1
Cianfarani, MA1
Gasbarra, E1
Tarantino, U1
Federici, M1

Other Studies

8 other studies available for thyroxine and Debility

ArticleYear
Low free triiodothyronine levels are associated with frail phenotype in hospitalized inpatients with cirrhosis.
    Postgraduate medicine, 2022, Volume: 134, Issue:5

    Topics: Aged; Creatinine; End Stage Liver Disease; Frail Elderly; Frailty; Humans; Inpatients; Liver Cirrhos

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Thyroid hormones and frailty in persons experiencing extreme longevity.
    Experimental gerontology, 2020, Volume: 138

    Topics: Aged, 80 and over; Frailty; Humans; Italy; Longevity; Thyroid Gland; Thyroid Hormones; Thyrotropin;

2020
Low free triiodothyronine levels are associated with risk of frailty in older adults with type 2 diabetes mellitus.
    Experimental gerontology, 2020, Volume: 138

    Topics: Aged; Diabetes Mellitus, Type 2; Frailty; Hand Strength; Humans; Thyroid Function Tests; Thyrotropin

2020
Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack.
    Clinical endocrinology, 2022, Volume: 96, Issue:2

    Topics: Brain; Frailty; Humans; Ischemic Attack, Transient; Stroke; Thyroxine

2022
High Circulating Free Thyroxine Levels May Increase the Risk of Frailty: The Rotterdam Study.
    The Journal of clinical endocrinology and metabolism, 2018, 01-01, Volume: 103, Issue:1

    Topics: Aged; Biomarkers; Cross-Sectional Studies; Female; Follow-Up Studies; Frailty; Humans; Male; Middle

2018
Degree of Peripheral Thyroxin Deiodination, Frailty, and Long-Term Survival in Hospitalized Older Patients.
    The Journal of clinical endocrinology and metabolism, 2018, 05-01, Volume: 103, Issue:5

    Topics: Aged; Aged, 80 and over; Female; Frailty; Geriatric Assessment; Halogenation; Hospitalization; Human

2018
Low FT3: a possible marker of frailty in the elderly.
    Clinical interventions in aging, 2017, Volume: 12

    Topics: Aged; Aged, 80 and over; Biomarkers; Comorbidity; Europe; Female; Frail Elderly; Frailty; Geriatric

2017