Compounds > thyroxine
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thyroxine and Deafness

thyroxine has been researched along with Deafness in 33 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
"The syndrome is caused by a single mutant recessive gene responsible for both the deafness and goitre."1.28Goitre and deaf-mutism. ( Elamin, A, 1991)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199027 (81.82)18.7374
1990's4 (12.12)18.2507
2000's2 (6.06)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NILSSON, LR1
BORGFORS, N1
GAMSTORP, I1
HOLST, HE1
LIDEN, G1
HOLLANDER, CS2
PROUT, TE1
RIENHOFF, M1
RUBEN, RJ1
ASPER, SP1
Paggi, A1
Cassone, R1
Lucisano, V1
Chieco, P1
Dalmaso, S1
Danese, V1
Corsi, V1
al-Jaberi, TM1
Hussein, AD1
Heis, HA1
François, M1
Bonfils, P1
Leger, J1
Avan, P1
Czernichow, P1
Narcy, P1
Gauthier, K1
Plateroti, M1
Harvey, CB1
Williams, GR1
Weiss, RE1
Refetoff, S4
Willott, JF1
Sundin, V1
Roux, JP1
Malaval, L1
Hara, M1
Samarut, J1
Chassande, O1
Ng, L1
Rüsch, A1
Amma, LL1
Nordström, K1
Erway, LC1
Vennström, B1
Forrest, D1
Chan, V1
Wang, C1
Yeung, RT1
Mendel, D1
Robinson, M1
Chopra, IJ1
Hershman, JM1
Hornabrook, RW1
Colquhoun, JP1
Elamin, A1
Friis, J1
Johnsen, T1
Feldt-Rasmussen, U1
Bech, K1
Friis, T1
Greig, WR1
Shenkman, L1
Medeiros-Neto, GA1
Mitsuma, T1
Monteiro, K1
Penna, M1
Pupo, AA1
Wiener, JD1
Levin, SE1
Klugman, LH1
Ritter, FN1
Harrison, MR1
Fierro-Benitez, R2
Ramirez, I1
Stanbury, JB2
Sundsfjord, JA1
Schjoth, A1
Odegaard, AE1
Harbitz, HF1
Hvidberg-Hansen, J1
Kiaer, HW1
Purves, RD1
Ibberston, HK1
Desai, KB1
Mehta, MN1
Patel, MC1
Ramanna, L1
Ganatra, RD1
Yamamoto, M2
Sakurada, T2
Yamaguchi, T2
Yoshida, K2
Matsui, K1
Ljunggren, JG1
Lindström, H1
Hjern, B1
Deol, MS1
Saito, S1
DeGroot, LJ1
Benard, B1
DeWind, LT1
Estrella, E1
Milutinovic, PS1
Tellez, MU1
Kitlak, W1
Gebert, P1
Malamos, B1
Koutras, DA1
Sfontouris, J1
Rigopoulos, G1
Wittig, G1

Reviews

2 reviews available for thyroxine and Deafness

ArticleYear
Radionuclide evaluation of thyroid disease in children.
    Seminars in nuclear medicine, 1973, Volume: 3, Issue:1

    Topics: Adult; Child; Child, Preschool; Congenital Hypothyroidism; Deafness; Diagnosis, Differential; Goiter

1973
[Sporadic goiter and congenital deafness. Pendred's syndrome].
    Ugeskrift for laeger, 1970, Sep-24, Volume: 132, Issue:39

    Topics: Deafness; Diagnosis, Differential; Goiter; Humans; Iodine; Perchlorates; Thyroiditis, Autoimmune; Th

1970

Other Studies

31 other studies available for thyroxine and Deafness

ArticleYear
NONENDEMIC GOITRE AND DEAFNESS.
    Acta paediatrica, 1964, Volume: 53

    Topics: Adolescent; Audiometry; Child; Deafness; Genetics, Medical; Goiter; Humans; Pathology; Thyroid Funct

1964
CONGENITAL DEAFNESS AND GOITER. STUDIES OF A PATIENT WITH A COCHLEAR DEFECT AND INADEQUATE FORMATION OF IODOTHYRONINES.
    The American journal of medicine, 1964, Volume: 37

    Topics: Cochlea; Congenital Abnormalities; Deafness; Diiodotyrosine; Goiter; Hearing Loss; Humans; Iodine Is

1964
[Echocardiographic study of 2 cases of Pendred syndrome].
    Minerva medica, 1982, Apr-02, Volume: 73, Issue:14

    Topics: Adult; Deafness; Echocardiography; Female; Goiter; Humans; Male; Myxedema; Radionuclide Imaging; Syn

1982
Management of goitre in Pendred's syndrome.
    The British journal of surgery, 1994, Volume: 81, Issue:10

    Topics: Adolescent; Adult; Deafness; Female; Goiter; Humans; Iodine; Male; Recurrence; Syndrome; Thyroid Gla

1994
Audiological assessment of eleven congenital hypothyroid infants before and after treatment.
    Acta oto-laryngologica, 1993, Volume: 113, Issue:1

    Topics: Auditory Threshold; Cochlea; Conditioning, Classical; Congenital Hypothyroidism; Deafness; Evoked Po

1993
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
    Molecular and cellular biology, 2001, Volume: 21, Issue:14

    Topics: Animals; Bone Development; Cysteine Endopeptidases; Deafness; Down-Regulation; Embryonic and Fetal D

2001
Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene.
    Human molecular genetics, 2001, Nov-01, Volume: 10, Issue:23

    Topics: Animals; Body Weight; Cochlea; Deafness; DNA-Binding Proteins; Evoked Potentials, Auditory, Brain St

2001
Dissociated thyroxine, triiodothyronine and reverse triiodothyronine levels in patients with familial goitre due to iodide organification defects.
    Clinical endocrinology, 1979, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Congenital Hypothyroidism; Deafness; Female; Goiter; Humans; Iodine; Male; Pedigr

1979
Electrocochleography in congenital hypothyroidism.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:5

    Topics: Acoustic Stimulation; Auditory Threshold; Brain Stem; Child, Preschool; Cochlea; Congenital Hypothyr

1978
Serum thyroid hormone and thyrotropin levels in subjects from endemic goiter regions of New Guinea.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Deafness; Female; Goiter, Endemic; Humans; Male; M

1975
Awakenings from within and without.
    Australian family physician, 1992, Volume: 21, Issue:6

    Topics: Deafness; Humans; Hypothyroidism; Thyroxine

1992
Goitre and deaf-mutism.
    Upsala journal of medical sciences, 1991, Volume: 96, Issue:3

    Topics: Adolescent; Child; Deafness; Goiter; Humans; Male; Syndrome; Thyroxine

1991
Thyroid function in patients with Pendred's syndrome.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Autoantibodies; Deafness; Female; Goiter; Humans; Male; Middle Aged; Thyrog

1988
Evidence for hypothyroidism in endemic cretinism in Brazil.
    Lancet (London, England), 1973, Jul-14, Volume: 2, Issue:7820

    Topics: Adult; Body Height; Brazil; Congenital Hypothyroidism; Deafness; Disease Reservoirs; Female; Goiter,

1973
Letter: Congenital deafness and hypothyroidism.
    Lancet (London, England), 1974, May-11, Volume: 1, Issue:7863

    Topics: Deafness; Female; Fetal Diseases; Goiter; Humans; Hypothyroidism; Maternal-Fetal Exchange; Pregnancy

1974
Pendred's syndrome in South African Bantu brothers.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, Aug-27, Volume: 40, Issue:32

    Topics: Black or African American; Black People; Child; Cholesterol; Deafness; Goiter; Humans; Male; Metabol

1966
The effects of hypothyroidism upon the ear, nose and throat. A clinical and experimental study.
    The Laryngoscope, 1967, Volume: 77, Issue:8

    Topics: Animals; Audiometry; Basal Metabolism; Body Weight; Chick Embryo; Congenital Hypothyroidism; Deafnes

1967
Immunoreactive growth hormone in endemic cretins in Ecuador.
    Lancet (London, England), 1968, May-04, Volume: 1, Issue:7549

    Topics: Adolescent; Adult; Anthropometry; Congenital Hypothyroidism; Deafness; Dwarfism, Pituitary; Ecuador;

1968
[Combined goiter and deafness as a hereditary condition (Pendred's syndrome)].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968, Jan-01, Volume: 88, Issue:1

    Topics: Adult; Deafness; Diagnosis, Differential; Female; Goiter; Hearing Tests; Humans; Iodine Radioisotope

1968
Goitre and deafness: Pendred's syndrome.
    The New Zealand medical journal, 1972, Volume: 76, Issue:483

    Topics: Adult; Deafness; Genes, Recessive; Goiter; Humans; Iodine; Male; Pedigree; Perchlorates; Syndrome; T

1972
Goitre and cretinism in the high Himalayas.
    The New Zealand medical journal, 1974, Dec-11, Volume: 80, Issue:529

    Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Deafness; Female; Goiter, Endemic; Humans; Hypo

1974
Thyroidal iodopriteins in Pendred's syndrome.
    The Journal of endocrinology, 1974, Volume: 63, Issue:2

    Topics: Adult; Albumins; Chromatography; Deafness; Female; Goiter; Humans; Iodine; Monoiodotyrosine; Syndrom

1974
[Case of Pendred's syndrome].
    Horumon to rinsho. Clinical endocrinology, 1974, Volume: 22, Issue:4

    Topics: Child; Deafness; Feedback; Goiter; Humans; Male; Syndrome; Thyrotropin; Thyroxine; Triiodothyronine

1974
The concentration of peroxidase in normal and adenomatous human thyroid tissue with special reference to patients with Pendred's syndrome.
    Acta endocrinologica, 1973, Volume: 72, Issue:2

    Topics: Aged; Deafness; Female; Goiter; Goiter, Nodular; Graves Disease; Humans; Iodine; Iodine Isotopes; Ma

1973
An experimental approach to the understanding and treatment of hereditary syndromes with congenital deafness and hypothyroidism.
    Journal of medical genetics, 1973, Volume: 10, Issue:3

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Cochlea; Deafness; Disease Models, Animal; Female

1973
The changes of serum triiodothyronine, thyroxine and thyroid stimulating hormone in two cases of hypothyroidism with unusual complications.
    The Tohoku journal of experimental medicine, 1974, Volume: 112, Issue:4

    Topics: Child; Deafness; Exophthalmos; Goiter; Humans; Hypothyroidism; Male; Middle Aged; Myxedema; Radioimm

1974
Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:8

    Topics: Adolescent; Bone Diseases, Developmental; Child; Deafness; Erythrocytes; Female; Fibroblasts; Goiter

1972
Endemic goiter with hypothyroidism in three generations.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12

    Topics: Adult; Aged; Blood Proteins; Congenital Hypothyroidism; Deafness; Female; Goiter; Goiter, Endemic; G

1969
[Clinical and chromosomal studies in a congenital hypothyroidism caused by thyroxin synthesis disorders and middle ear hearing disorders (Pendred- or goiter-deafness syndrome)].
    Archiv fur Kinderheilkunde, 1968, Volume: 177, Issue:2

    Topics: Adult; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Deafness; Female; Goit

1968
Inborn errors of iodine metabolism in Greece.
    Nuclear-Medizin, 1964, Apr-01, Volume: 4, Issue:1

    Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Deafness; Female; Goiter; Greece; Humans; Hypot

1964
[On the goiter-deafness syndrome (Pendred)].
    Zentralblatt fur Chirurgie, 1965, Volume: 90, Issue:26

    Topics: Adolescent; Cell Division; Deafness; Female; Graves Disease; Humans; Peroxidases; Thyroxine

1965