Page last updated: 2024-11-06

thyroxine and Cushing's Syndrome

thyroxine has been researched along with Cushing's Syndrome in 36 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"Objectives The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis, hyperthyroidism and hypercortisolism in cats with diabetes mellitus."7.85Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands. ( Kooistra, HS; Prins, M; Reusch, CE; Riond, B; Schaefer, S; Steiner, JM; Suchodolski, JS; Zini, E, 2017)
" Several cases of Cushing's syndrome have been reported when patients received inhaled therapy with fluticasone for asthma, sometimes complicated by secondary adrenal failure after stopping fluticasone."7.75[Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone]. ( Beressi, J-; Collet-Gaudillat, C; Desforges-Bullet, V; Doll, J; Petit-Aubert, G; Roussin-Bretagne, S, 2009)
"Objectives The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis, hyperthyroidism and hypercortisolism in cats with diabetes mellitus."3.85Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands. ( Kooistra, HS; Prins, M; Reusch, CE; Riond, B; Schaefer, S; Steiner, JM; Suchodolski, JS; Zini, E, 2017)
" Several cases of Cushing's syndrome have been reported when patients received inhaled therapy with fluticasone for asthma, sometimes complicated by secondary adrenal failure after stopping fluticasone."3.75[Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone]. ( Beressi, J-; Collet-Gaudillat, C; Desforges-Bullet, V; Doll, J; Petit-Aubert, G; Roussin-Bretagne, S, 2009)
"Cortisol secreting pheochromocytoma is rarely reported in literature."1.36Cushing syndrome in an infant due to cortisol secreting adrenal pheochromocytoma: a rare association. ( Khurana, N; Kumar, M; Kumar, V; Mohta, A; Talukdar, B, 2010)
"Although exophthalmos has often been included in clinical descriptions, no previous study has reported actual measurements in patients with active and treated Cushing's syndrome, and in control patients."1.29Exophthalmos in Cushing's syndrome. ( Kelly, W, 1996)
"We conclude that hypercortisolism may be a manifestation of hyperthyroidism, and the evaluation of Cushing's syndrome should include thyroid function tests."1.28Subacute thyroiditis presenting as Cushing's syndrome. Case report. ( Blethen, SL; Romano, A, 1991)
"We conclude that hypercortisolism is responsible for the abnormalities in anterior pituitary function in Cushing's syndrome."1.28Anterior pituitary function in Cushing's syndrome: study of 36 patients. ( Astigarraga, B; Bernabeu, I; Cuerda, C; Diez, S; Estrada, J; Marazuela, M; Salto, L; Vicente, A, 1991)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's8 (22.22)18.2507
2000's4 (11.11)29.6817
2010's3 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tamada, D1
Kitamura, T1
Onodera, T1
Hamasaki, T1
Otsuki, M1
Shimomura, I1
Schaefer, S1
Kooistra, HS1
Riond, B1
Suchodolski, JS1
Steiner, JM1
Prins, M1
Zini, E1
Reusch, CE1
Collet-Gaudillat, C1
Roussin-Bretagne, S1
Desforges-Bullet, V1
Petit-Aubert, G1
Doll, J1
Beressi, J-1
Roelfsema, F1
Pereira, AM1
Biermasz, NR1
Frolich, M1
Keenan, DM1
Veldhuis, JD1
Romijn, JA1
Kumar, M1
Kumar, V1
Talukdar, B1
Mohta, A1
Khurana, N1
BENNHOLD, H1
LAMBERG, BA1
Pishdad, GR1
Silva, BC1
Baruqui Júnior, AM1
Barbosa, VE1
Pena, GP1
Campos, MH1
Ramos, AV1
Dias, EP1
James, JA1
Appelqvist, P1
Kostianinen, S1
Lancranjan, I1
Haraguchi, K1
Hiramatsu, K1
Onaya, T1
Visser, TJ1
Lamberts, SW1
Kraft, W1
Dietl, A1
Kelly, W1
Otsuka, F1
Ogura, T1
Nakao, K1
Hayakawa, N1
Mimura, Y1
Yamauchi, T1
Makino, H1
Duick, DS1
Wahner, HW1
Schnall, AM1
Brodkey, JS1
Kaufman, B1
Pearson, OH1
Slavnov, VN2
Luchitskiĭ, EV2
Kommisarenko, IV1
Cheban, AK1
Kuku, SF1
Child, DF1
Nader, S1
Fraser, TR1
Takeda, Y1
Komissarenko, IV1
Boujon, CE1
Ritz, U1
Rossi, GL1
Bestetti, GE1
Romano, A1
Blethen, SL1
Cuerda, C1
Estrada, J1
Marazuela, M1
Vicente, A1
Astigarraga, B1
Bernabeu, I1
Diez, S1
Salto, L1
Comtois, R1
Hébert, J1
Soucy, JP1
Benker, G1
Raida, M1
Olbricht, T1
Wagner, R1
Reinhardt, W1
Reinwein, D1
Williams, G1
Spinks, TJ1
Freemantle, C1
Sandler, L1
Joplin, GF1
Lukert, BP1
Higgins, JC1
Stoskopf, MM1
Purves, HD1
Hershman, JM1
Pittman, JA1
Blichert-Toft, M1
Hummer, L1
Dige-Petersen, H1
Saeed-uz-Zafar, M1
Mellinger, RC1
Morrow, LB1
Mosier, HD1
Smith, FG1
Schultz, MA1
Murphy, BE1

Reviews

5 reviews available for thyroxine and Cushing's Syndrome

ArticleYear
THE PATHOGENETIC CONSEQUENCES OF FAILURE OF CERTAIN TRANSPORT FUNCTIONS IN THE HUMAN ORGANISM.
    Triangle; the Sandoz journal of medical science, 1963, Volume: 6

    Topics: Blood Circulation; Blood Protein Disorders; Blood Proteins; Cardiovascular System; Cushing Syndrome;

1963
[Subclinical Cushing's disease: presentation of three cases and critical review].
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:4

    Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Magnetic

2007
Multiple thoracotomy combined with chemotherapy in metastatic adrenal cortical carcinoma: a case report and review of the literature.
    Journal of surgical oncology, 1983, Volume: 24, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Carcinoma; Cortisone; Cushing Syndrom

1983
The endocrine profile of bromocriptine: its application in endocrine diseases.
    Journal of neural transmission, 1981, Volume: 51, Issue:1-2

    Topics: Bromocriptine; Cushing Syndrome; Endocrine Glands; Growth Hormone; Hormones; Humans; Huntington Dise

1981
Hypophyseal growth hormone. II. Interaction with other hormones.
    Henry Ford Hospital medical journal, 1970,Fall, Volume: 18, Issue:3

    Topics: Adrenocorticotropic Hormone; Androgens; Animals; Catecholamines; Cushing Syndrome; Estrogens; Glucag

1970

Trials

1 trial available for thyroxine and Cushing's Syndrome

ArticleYear
Response to synthetic thyrotropin-releasing hormone in man.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:4

    Topics: Adenoma, Chromophobe; Adolescent; Adult; Clinical Trials as Topic; Cushing Syndrome; Female; Humans;

1970

Other Studies

30 other studies available for thyroxine and Cushing's Syndrome

ArticleYear
Clinical significance of fluctuations in thyroid hormones after surgery for Cushing's syndrome.
    Endocrine journal, 2015, Volume: 62, Issue:9

    Topics: Adrenalectomy; Adult; Cushing Syndrome; Female; Follow-Up Studies; Humans; Hydrocortisone; Male; Mid

2015
Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands.
    Journal of feline medicine and surgery, 2017, Volume: 19, Issue:8

    Topics: Acromegaly; Adrenal Cortex Hormones; Animals; Cat Diseases; Cats; Creatinine; Cushing Syndrome; Diab

2017
[Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone].
    Annales d'endocrinologie, 2009, Volume: 70, Issue:4

    Topics: Administration, Inhalation; Adrenocorticotropic Hormone; Androstadienes; Blood Glucose; Bronchodilat

2009
Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome.
    European journal of endocrinology, 2009, Volume: 161, Issue:5

    Topics: Adult; Circadian Rhythm; Cushing Syndrome; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal S

2009
Cushing syndrome in an infant due to cortisol secreting adrenal pheochromocytoma: a rare association.
    Journal of pediatric endocrinology & metabolism : JPEM, 2010, Volume: 23, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Calcium; Combined Modality Therapy; Cushing

2010
CUSHING'S SYNDROME CO-EXISTING WITH HYPERTHYROIDISM. REPORT OF A CASE AND SOME METABOLIC OBSERVATIONS.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Blood Chemical Analysis; Choles

1964
Cushing's syndrome as a manifestation of hypothyroidism.
    Clinical endocrinology, 2004, Volume: 60, Issue:2

    Topics: Adrenal Insufficiency; Cushing Syndrome; Female; Fludrocortisone; Glucocorticoids; Humans; Hypothyro

2004
The hypophysis.
    The Journal of laryngology and otology, 1967, Volume: 81, Issue:12

    Topics: Adult; Aged; Cortisone; Cryosurgery; Cushing Syndrome; Diabetes Insipidus; Diabetic Retinopathy; Ele

1967
Transient thyrotoxicosis after unilateral adrenalectomy in two patients with Cushing's syndrome.
    Endocrinologia japonica, 1984, Volume: 31, Issue:5

    Topics: Adrenalectomy; Adult; Cushing Syndrome; Female; Humans; Hyperthyroidism; Male; Thyroxine; Time Facto

1984
Regulation of TSH secretion and thyroid function in Cushing's disease.
    Acta endocrinologica, 1981, Volume: 96, Issue:4

    Topics: Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Thyroid Gland; Thyrotropin; Thyroxine; Triio

1981
[Total thyroxine (T4) and free thyroxine (FT4) in hypothyroidism and nonthyroid diseases of dogs].
    Tierarztliche Praxis, 1994, Volume: 22, Issue:5

    Topics: Alopecia; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; Dogs;

1994
Exophthalmos in Cushing's syndrome.
    Clinical endocrinology, 1996, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cushing Syndrome; Exophthalmos; Female; Graves Disease;

1996
Cushing's syndrome due to unilateral adrenocortical hyperplasia.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Corticotropin

1998
Thyroid axis in patients with Cushing's syndrome.
    Archives of internal medicine, 1979, Volume: 139, Issue:7

    Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Middle Aged; Thyroid Func

1979
Pituitary function after removal of pituitary microadenomas in Cushing's disease.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adult; Cushing Syndrome; Follicle Stimulating Hormone; Humans; Hydrocortis

1978
[Hypothalamo-hypophyseal-thyroid relationship in patients with Itsenko-Cushing disease treated with chloditan].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:8

    Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Hypothalamo-Hypophyseal System; Male; Middle Ag

1978
Thyrotrophin and prolactin responsiveness to thyrotrophin releasing hormone in Cushing's disease.
    Clinical endocrinology, 1975, Volume: 4, Issue:4

    Topics: Cushing Syndrome; Depression, Chemical; Gold Radioisotopes; Humans; Hydrocortisone; Hypothalamus; Pi

1975
[Clinical studies on regulatory system of thyroid hormone secretion and serum triiodothyronine. Part. I. Solid-state radioimmunoassy for human serum TSH and its clinical application (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1975, Jan-20, Volume: 51, Issue:1

    Topics: Animals; Cushing Syndrome; Goiter, Nodular; Graves Disease; Humans; Hypothyroidism; Rabbits; Radioim

1975
[Functional condition of the thyroid gland and thyrotropic activity of the hypophysis in Itsenko-Cushing disease].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Blood Proteins; Cushing Syndrome; Humans; Middle Aged; Pituitary Gland; Thyroid G

1977
A clinico-pathological study of canine Cushing's disease caused by a pituitary carcinoma.
    Journal of comparative pathology, 1991, Volume: 105, Issue:3

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Biomarkers, Tumor; Brain Neoplasms; Calcinosis

1991
Subacute thyroiditis presenting as Cushing's syndrome. Case report.
    Hormone research, 1991, Volume: 35, Issue:3-4

    Topics: Acute Disease; Adrenal Glands; Adult; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Huma

1991
Anterior pituitary function in Cushing's syndrome: study of 36 patients.
    Endocrinologia japonica, 1991, Volume: 38, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Child; Cushing Syndrome; Drug Combination

1991
Reversible hypertriiodothyroninaemia due to adrenal insufficiency.
    Journal of internal medicine, 1991, Volume: 230, Issue:1

    Topics: Adrenal Insufficiency; Adult; Cushing Syndrome; Female; Humans; Postoperative Complications; Thyroid

1991
TSH secretion in Cushing's syndrome: relation to glucocorticoid excess, diabetes, goitre, and the 'sick euthyroid syndrome'.
    Clinical endocrinology, 1990, Volume: 33, Issue:6

    Topics: Adult; Cushing Syndrome; Diabetes Mellitus; Euthyroid Sick Syndromes; Female; Goiter; Humans; Hydroc

1990
Total body calcium measurements using neutron-activation analysis in Cushing's syndrome.
    Calcified tissue international, 1986, Volume: 39, Issue:3

    Topics: Adrenalectomy; Adult; Aged; Brachytherapy; Calcium; Cushing Syndrome; Female; Humans; Hydrocortisone

1986
Serum osteocalcin is increased in patients with hyperthyroidism and decreased in patients receiving glucocorticoids.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:5

    Topics: Adult; Aged; Alkaline Phosphatase; Calcium; Calcium-Binding Proteins; Cushing Syndrome; Female; Gluc

1986
Purves symposium: 2. Pituitary morphology in relationship to function. General principles.
    The New Zealand medical journal, 1974, Dec-25, Volume: 80, Issue:530

    Topics: Adrenocorticotropic Hormone; Animals; Cushing Syndrome; Cytoplasmic Granules; Estrogens; Follicle St

1974
Pituitary-thyroid function after total adrenalectomy in patients with Cushing's disease.
    Acta endocrinologica, 1974, Volume: 76, Issue:4

    Topics: Adrenalectomy; Adult; Cortisone; Cushing Syndrome; Female; Humans; Immunoelectrophoresis; Injections

1974
Failure of catch-up growth after Cushing's syndrome in childhood.
    American journal of diseases of children (1960), 1972, Volume: 124, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adrenocorticotropic Hormone;

1972
Radioassays of non-antigenic hormones.
    Transactions of the Association of American Physicians, 1968, Volume: 81

    Topics: Antigens; Cushing Syndrome; Hormones; Humans; Hydrocortisone; Hyperthyroidism; Hypothyroidism; Metho

1968