thyroxine has been researched along with Critical Illness in 53 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To maintain TSH levels in the normal range, it may be necessary to increase the L-thyroxine dose of critically ill patients with hypothyroidism." | 7.76 | Increased levothyroxine requirements in critically ill patients with hypothyroidism. ( Albertini, R; Ferrari, M; Imberti, R; Iotti, GA; Rizzo, V; Tinelli, C, 2010) |
| "To evaluate the role of adrenal and thyroid hormones in the prediction of death in a population of critically ill puppies with parvoviral diarrhea by measuring serial daily serum concentrations of cortisol and thyroxine." | 7.74 | Serum cortisol and thyroxine concentrations as predictors of death in critically ill puppies with parvoviral diarrhea. ( Goddard, A; Herrtage, ME; Schoeman, JP, 2007) |
| "To analyse the influence of selenium substitution on thyroid hormone metabolism in patients with severe sepsis." | 5.11 | Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients. ( Angstwurm, MW; Gaertner, R; Schopohl, J, 2004) |
| "To maintain TSH levels in the normal range, it may be necessary to increase the L-thyroxine dose of critically ill patients with hypothyroidism." | 3.76 | Increased levothyroxine requirements in critically ill patients with hypothyroidism. ( Albertini, R; Ferrari, M; Imberti, R; Iotti, GA; Rizzo, V; Tinelli, C, 2010) |
| "To evaluate the role of adrenal and thyroid hormones in the prediction of death in a population of critically ill puppies with parvoviral diarrhea by measuring serial daily serum concentrations of cortisol and thyroxine." | 3.74 | Serum cortisol and thyroxine concentrations as predictors of death in critically ill puppies with parvoviral diarrhea. ( Goddard, A; Herrtage, ME; Schoeman, JP, 2007) |
| "The low plasma triiodothyronine (T3) observed during prolonged critical illness can be explained in part by suppressed hepatic deiodinase type I (D1) and increased D3 activity." | 3.74 | Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness. ( Darras, VM; Debaveye, Y; Ellger, B; Mebis, L; Van den Berghe, G, 2008) |
| "One hundred and eighty patients had serum thyrotropin, total triiodothyronine and free thyroxine concentrations measured within 3 h of admission to the Intensive Therapy Unit to assess whether thyroid function tests could predict outcome in critical illness." | 3.69 | Relationship of admission thyroid function tests to outcome in critical illness. ( Beckett, GJ; Drummond, GB; Ray, DC; Wilkinson, E, 1995) |
| "To evaluate the 24-h pattern of serum thyrotropin (TSH) in critically ill patients, we measured serum concentrations of TSH in blood samples collected every 2 h for 24 h from nine patients (six with malignancy, two with liver cirrhosis, one with chronic renal failure), who had subnormal levels of both triiodothyronine (T3) and thyroxine (T4), in the absence of history, symptoms or signs of thyroid disease." | 3.68 | Alterations in circadian rhythm of serum thyrotropin in critically ill patients. ( Custro, N; Notarbartolo, A; Scafidi, V, 1992) |
| "The inflammatory response of critical illness is accompanied by nonthyroidal illness syndrome (NTIS)." | 2.94 | Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation. ( Bianco, AC; Bocco, BMLC; Braunschweig, CA; Fernandes, GW; Fonseca, TL; Freels, S; Lateef, O; McKeever, L; Mozer, M; Nowak, K; Peterson, SJ; Roehl, K, 2020) |
| "Both critical illness and fasting induce low circulating thyroid hormone levels in the absence of a rise in TSH, a constellation-labeled nonthyroidal illness syndrome (NTI)." | 2.78 | Impact of early nutrient restriction during critical illness on the nonthyroidal illness syndrome and its relation with outcome: a randomized, controlled clinical study. ( Boelen, A; Casaer, MP; Langouche, L; Marques, M; Van den Berghe, G; Vander Perre, S; Wouters, PJ, 2013) |
| "In a rabbit model of prolonged critical illness, gene expression levels of MCT8 in liver and of MCT10 in skeletal muscle were increased as compared with healthy controls." | 2.74 | Expression of thyroid hormone transporters during critical illness. ( D'Hoore, A; Darras, VM; Debaveye, Y; Ellger, B; Langouche, L; Mebis, L; Paletta, D; Van den Berghe, G; Visser, TJ, 2009) |
| "Critical illness is often associated with reduced TSH and thyroid hormone secretion as well as marked changes in peripheral thyroid hormone metabolism, resulting in low serum T(3) and high rT(3) levels." | 2.71 | Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. ( Kaptein, E; Peeters, RP; Van den Berghe, G; van Toor, H; Visser, TJ; Wouters, PJ, 2003) |
| " Infusion of TRH alone or in combination with GH secretagogues augmented nonpulsatile TSH release 2- to 5-fold; only TRH + GHRP-2 increased pulsatile TSH secretion (4-fold)." | 2.69 | Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues. ( Baxter, RC; Bouillon, R; Bowers, CY; de Zegher, F; Lauwers, P; Schetz, M; Van den Berghe, G; Van der Vorst, E; Veldhuis, JD; Verwaest, C; Wouters, P, 1998) |
| "During prolonged critical illness, mean night-time serum concentrations of TSH (1." | 2.68 | Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues. ( Bouillon, R; Bowers, CY; de Zegher, F; Gouwy, S; Lauwers, P; Schetz, M; Stockman, W; Van den Berghe, G; Veldhuis, JD; Weekers, F; Wouters, P, 1997) |
| "As a consequence, the sick euthyroid syndrome of severely ill patients receiving dopamine may be not an adaptive mechanism, but a condition of iatrogenic hypothyroidism." | 2.67 | Dopamine and the sick euthyroid syndrome in critical illness. ( de Zegher, F; Lauwers, P; Van den Berghe, G, 1994) |
| "Pathogenesis of NTIS in long-term critical illness is more complex and includes suppression of hypothalamic thyrotropin-releasing hormone, accounting for persistently reduced secretion of thyroid-stimulating hormone despite low plasma thyroid hormone." | 2.52 | Thyroid function in critically ill patients. ( Bianco, AC; Boelen, A; Fliers, E; Langouche, L, 2015) |
| "With increase in severity of critical illness assessed by APACHE III, TFT, that is, TT3, TT4, and FT3 levels were decreasing, suggestive of increasing non-thyroidal illness in critically ill patients." | 1.72 | Study of Thyroid Functions in critically ill Patients admitted in Medical Intensive Care Unit and its Correlation with Critical Care Scoring Acute Physiology and Chronic Health Evaluation III. ( Chaudhary, G; Kanchi, G; Mahashabde, M; Murukoti, SR; Patil, R, 2022) |
| "Children with sepsis have a higher incidence rate of NTIS than those without sepsis." | 1.56 | [Association of non-thyroidal illness syndrome with interleukin-6 and interleukin-10 in critically ill children with sepsis]. ( Bai, XF; Cao, LJ; Kang, L; Li, LJ; Liu, G; Shi, XN; Xu, MX; Zhao, X, 2020) |
| "Alterations in thyroid hormones during critical illness, known as non-thyroidal illness syndrome (NTIS), were suggested to have a prognostic value." | 1.51 | [Prevalence and prognostic value of non-thyroidal illness syndrome among critically ill children]. ( El-Dihemey, MA; El-Ella, SSA; El-Mekkawy, MS, 2019) |
| "For patients with critical illness, the early two-step thyroid screening strategy (starting with an isolated TSH determination between 24 and 48h after admission) led to a saving of 50% in fT4 and fT3 tests, with a false-negative rate of 1." | 1.43 | Two-step thyroid screening strategy in the critical patient. ( Barcelo, A; Bauça, JM; Elorza, MA; Morell-Garcia, D, 2016) |
| "Critical illness in patients with polytrauma leaded to trauma severity-dependent alterations of the thyroid axis response early after injury." | 1.42 | Dynamic neuroendocrine changes in critically ill patients with polytrauma. ( Galusova, A; Imrich, R; Mackova, J; Majek, M; Meskova, M; Pauliny, M; Penesova, A; Vlcek, M, 2015) |
| "Both starvation and critical illness are hallmarked by changes in circulating thyroid hormone parameters with typically low T(3) concentrations in the absence of elevated TSH." | 1.38 | Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study. ( Darras, VM; Derde, S; Eerdekens, A; Güiza, F; Langouche, L; Mebis, L; Princen, L; Van den Berghe, G; Vanhorebeek, I; Vanwijngaerden, YM, 2012) |
| "Hypothyroidism is cited as an uncommon cause of ventilator-dependent respiratory failure." | 1.32 | Hypothyroidism and failure to wean in patients receiving prolonged mechanical ventilation at a regional weaning center. ( Datta, D; Scalise, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (30.19) | 18.2507 |
| 2000's | 19 (35.85) | 29.6817 |
| 2010's | 12 (22.64) | 24.3611 |
| 2020's | 6 (11.32) | 2.80 |
| Authors | Studies |
|---|---|
| Mahashabde, M | 1 |
| Murukoti, SR | 1 |
| Chaudhary, G | 1 |
| Kanchi, G | 1 |
| Patil, R | 1 |
| Besci, T | 1 |
| Besci, Ö | 1 |
| Arslan, G | 1 |
| Ilgaz, H | 1 |
| Prencuva, P | 1 |
| Özdemir, G | 1 |
| Abacı, A | 1 |
| Demir, K | 1 |
| Dai, JJ | 1 |
| Du, DF | 1 |
| Ma, G | 1 |
| Jiang, MJ | 1 |
| McKeever, L | 1 |
| Peterson, SJ | 1 |
| Lateef, O | 1 |
| Freels, S | 1 |
| Fonseca, TL | 1 |
| Bocco, BMLC | 1 |
| Fernandes, GW | 1 |
| Roehl, K | 1 |
| Nowak, K | 1 |
| Mozer, M | 1 |
| Bianco, AC | 2 |
| Braunschweig, CA | 1 |
| Neiman, DJ | 1 |
| Bruyette, DS | 1 |
| Bergman, PJ | 1 |
| Xu, MX | 1 |
| Liu, G | 1 |
| Cao, LJ | 1 |
| Bai, XF | 1 |
| Kang, L | 1 |
| Zhao, X | 1 |
| Shi, XN | 1 |
| Li, LJ | 1 |
| Kumar, E | 1 |
| McCurdy, MT | 1 |
| Koch, CA | 1 |
| Hamadah, A | 1 |
| Fülöp, T | 1 |
| Gharaibeh, KA | 1 |
| El-Ella, SSA | 1 |
| El-Mekkawy, MS | 1 |
| El-Dihemey, MA | 1 |
| Zhang, D | 1 |
| Gao, L | 1 |
| Ye, H | 1 |
| Chi, R | 1 |
| Wang, L | 1 |
| Hu, L | 1 |
| Ouyang, X | 1 |
| Hou, Y | 1 |
| Deng, Y | 1 |
| Long, Y | 1 |
| Xiong, W | 1 |
| Chen, C | 1 |
| Fliers, E | 2 |
| Langouche, L | 4 |
| Boelen, A | 2 |
| Galusova, A | 1 |
| Pauliny, M | 1 |
| Majek, M | 1 |
| Mackova, J | 1 |
| Meskova, M | 1 |
| Vlcek, M | 1 |
| Imrich, R | 1 |
| Penesova, A | 1 |
| Raj, MN | 1 |
| Suresh, V | 1 |
| Mukka, A | 1 |
| Reddy, A | 1 |
| Sachan, A | 1 |
| Mohan, A | 1 |
| Vengamma, B | 1 |
| Rao, PV | 1 |
| Morell-Garcia, D | 1 |
| Bauça, JM | 1 |
| Elorza, MA | 1 |
| Barcelo, A | 1 |
| Mebis, L | 4 |
| Paletta, D | 1 |
| Debaveye, Y | 2 |
| Ellger, B | 2 |
| D'Hoore, A | 1 |
| Darras, VM | 4 |
| Visser, TJ | 5 |
| Van den Berghe, G | 11 |
| Derde, S | 2 |
| Vanhorebeek, I | 2 |
| Ververs, EJ | 1 |
| Vanhees, I | 1 |
| Van Herck, E | 1 |
| Larsson, L | 1 |
| Suvarna, JC | 1 |
| Fande, CN | 1 |
| Imberti, R | 1 |
| Ferrari, M | 1 |
| Albertini, R | 1 |
| Rizzo, V | 1 |
| Tinelli, C | 1 |
| Iotti, GA | 1 |
| Kadivar, M | 1 |
| Parsaei, R | 1 |
| Setoudeh, A | 1 |
| Eerdekens, A | 1 |
| Güiza, F | 1 |
| Princen, L | 1 |
| Vanwijngaerden, YM | 1 |
| Vander Perre, S | 1 |
| Marques, M | 1 |
| Wouters, PJ | 3 |
| Casaer, MP | 1 |
| Peeters, RP | 2 |
| Kaptein, E | 2 |
| van Toor, H | 4 |
| Angstwurm, MW | 1 |
| Schopohl, J | 1 |
| Gaertner, R | 1 |
| Datta, D | 1 |
| Scalise, P | 1 |
| Simpson, J | 1 |
| Williams, FL | 1 |
| Delahunty, C | 1 |
| Wu, SY | 1 |
| Ogston, SA | 1 |
| Hume, R | 1 |
| Zuppa, AF | 1 |
| Nadkarni, V | 2 |
| Davis, L | 1 |
| Adamson, PC | 1 |
| Helfaer, MA | 1 |
| Elliott, MR | 1 |
| Abrams, J | 1 |
| Durbin, D | 1 |
| Kester, MH | 1 |
| Unmehopa, UA | 1 |
| Alkemade, A | 1 |
| Niemczyk, S | 1 |
| Woźniacki, L | 1 |
| Schoeman, JP | 2 |
| Goddard, A | 1 |
| Herrtage, ME | 2 |
| Anand, NK | 1 |
| Chandra, V | 1 |
| Sinha, RS | 1 |
| Chellani, H | 1 |
| de Zegher, F | 3 |
| Lauwers, P | 3 |
| Stockigt, JR | 1 |
| Wilcox, RB | 1 |
| Nelson, JC | 1 |
| Tomei, RT | 1 |
| Rothwell, PM | 1 |
| Udwadia, ZF | 1 |
| Lawler, PG | 1 |
| Arem, R | 1 |
| Wiener, GJ | 1 |
| Kaplan, SG | 1 |
| Kim, HS | 1 |
| Reichlin, S | 1 |
| Kaplan, MM | 1 |
| Lim, CF | 1 |
| Docter, R | 1 |
| Krenning, EP | 1 |
| Bernard, B | 1 |
| de Jong, M | 1 |
| Hennemann, G | 1 |
| Ray, DC | 1 |
| Drummond, GB | 1 |
| Wilkinson, E | 1 |
| Beckett, GJ | 1 |
| Loh, KC | 1 |
| Eng, PC | 1 |
| Mechanick, JI | 1 |
| Sacks, HS | 1 |
| Cobin, RH | 1 |
| Veldhuis, JD | 2 |
| Wouters, P | 2 |
| Gouwy, S | 1 |
| Stockman, W | 1 |
| Weekers, F | 1 |
| Schetz, M | 2 |
| Bouillon, R | 2 |
| Bowers, CY | 2 |
| Vogeser, M | 1 |
| Jacob, K | 1 |
| Baxter, RC | 2 |
| Verwaest, C | 1 |
| Van der Vorst, E | 1 |
| Hawker, FH | 1 |
| To, C | 1 |
| Stewart, PM | 1 |
| Holman, SR | 1 |
| Katz, K | 1 |
| Lawler, J | 1 |
| Wax, J | 1 |
| O'Connor, R | 1 |
| Kabadi, UM | 1 |
| Stathatos, N | 1 |
| Levetan, C | 1 |
| Burman, KD | 1 |
| Wartofsky, L | 1 |
| Cogo, PE | 1 |
| Carnielli, VP | 1 |
| Rosso, F | 1 |
| Cesarone, A | 1 |
| Giordano, G | 1 |
| Faggian, D | 1 |
| Plebani, M | 1 |
| Barreca, A | 1 |
| Zacchello, F | 1 |
| Umpierrez, GE | 1 |
| Custro, N | 1 |
| Scafidi, V | 1 |
| Notarbartolo, A | 1 |
| Maldonado, LS | 1 |
| Murata, GH | 1 |
| Hershman, JM | 1 |
| Braunstein, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feeding the Critically Ill During Phases of Altered Redox Status (FEDOX): a Prospective Randomized Trial[NCT03085615] | 35 participants (Actual) | Interventional | 2017-03-15 | Completed | |||
| Impact of Early Parenteral Nutrition Completing Enteral Nutrition in Adult Critically Ill Patients[NCT00512122] | Phase 4 | 4,640 participants (Actual) | Interventional | 2007-08-31 | Active, not recruiting | ||
| Thyroid Function in Term and Near Term Infants With Respiratory Distress and Its' Relation to Severity of Illness[NCT00293956] | 20 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| "Reducing Elevated Heart Rate in Patients With Multiple Organ Dysfunction Syndrome (MODS) by the Funny Channel Current (If) Inhibitor Ivabradine"[NCT01186783] | Phase 2 | 70 participants (Anticipated) | Interventional | 2010-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for thyroxine and Critical Illness
| Article | Year |
|---|---|
Thyroid function in critically ill patients.
Topics: Critical Illness; Euthyroid Sick Syndromes; Humans; Hypothalamo-Hypophyseal System; Thyroid Gland; T | 2015 |
The hypothalamus-pituitary-thyroid axis in critical illness.
Topics: Animals; Critical Illness; Cytokines; Humans; Hypothalamo-Hypophyseal System; Iodide Peroxidase; Thy | 2009 |
Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland.
Topics: Critical Illness; Depression; Feedback, Physiological; Humans; Hypothalamus; Iodide Peroxidase; Iodo | 2006 |
[Thyroid hormones disturbances in critical ill patients--low T3 syndrome].
Topics: Critical Illness; Diagnosis, Differential; Endocrine System Diseases; Euthyroid Sick Syndromes; Huma | 2005 |
The controversy of the treatment of critically ill patients with thyroid hormone.
Topics: Animals; Critical Care; Critical Illness; Heart Diseases; Humans; Infections; Respiration; Shock; Th | 2001 |
Euthyroid sick syndrome.
Topics: Critical Illness; Euthyroid Sick Syndromes; Humans; Starvation; Thyroid Hormones; Thyroxine; Triiodo | 2002 |
9 trials available for thyroxine and Critical Illness
| Article | Year |
|---|---|
Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation.
Topics: Critical Illness; Energy Intake; Enteral Nutrition; Euthyroid Sick Syndromes; Female; Humans; Male; | 2020 |
Expression of thyroid hormone transporters during critical illness.
Topics: Aged; Amino Acid Transport Systems, Neutral; Animals; Base Sequence; Critical Illness; Disease Model | 2009 |
Impact of early nutrient restriction during critical illness on the nonthyroidal illness syndrome and its relation with outcome: a randomized, controlled clinical study.
Topics: Aged; Critical Care; Critical Illness; Fasting; Female; Food Deprivation; Humans; Leptin; Male; Midd | 2013 |
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients.
Topics: Aged; Aged, 80 and over; Biopsy; Critical Illness; Humans; Hyperglycemia; Hypoglycemic Agents; Insul | 2003 |
Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients.
Topics: Antioxidants; APACHE; Critical Illness; Female; Glutathione; Humans; Iodide Peroxidase; Male; Middle | 2004 |
Dopamine and the sick euthyroid syndrome in critical illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Depression, Chemical; Dopamine; Euthyr | 1994 |
Hypothalamic-pituitary axis dysfunction in critically ill patients with a low free thyroxine index.
Topics: Adult; Aged; Aged, 80 and over; Critical Care; Critical Illness; Female; Humans; Hypothalamo-Hypophy | 1997 |
Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues.
Topics: Adult; Aged; Critical Illness; Cross-Over Studies; Female; Growth Hormone-Releasing Hormone; Half-Li | 1997 |
Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Growth Hormone-Releasing Hormone; Human Gr | 1998 |
38 other studies available for thyroxine and Critical Illness
| Article | Year |
|---|---|
Study of Thyroid Functions in critically ill Patients admitted in Medical Intensive Care Unit and its Correlation with Critical Care Scoring Acute Physiology and Chronic Health Evaluation III.
Topics: APACHE; Critical Care; Critical Illness; Humans; Intensive Care Units; Thyroid Hormones; Thyrotropin | 2022 |
Biochemical indicators of euthyroid sick syndrome in critically ill children.
Topics: Albumins; Child; Critical Illness; Euthyroid Sick Syndromes; Humans; Lactates; Thyroid Function Test | 2022 |
Association between serum-free thyroxine level and all-cause mortality in critically ill patients: a retrospective study from MIMIC-IV.
Topics: Critical Care; Critical Illness; Humans; Retrospective Studies; Thyroid Function Tests; Thyroxine | 2023 |
Prognostic value of serum total thyroxine concentration at admission to an intensive care unit for critically ill dogs.
Topics: Animals; Critical Illness; Dog Diseases; Dogs; Hospitalization; Intensive Care Units; Prognosis; Ret | 2020 |
[Association of non-thyroidal illness syndrome with interleukin-6 and interleukin-10 in critically ill children with sepsis].
Topics: Child; Critical Illness; Euthyroid Sick Syndromes; Humans; Interleukin-10; Interleukin-6; Retrospect | 2020 |
Impairment of Thyroid Function in Critically Ill Patients in the Intensive Care Units.
Topics: Aged; Critical Illness; Female; Humans; Hypotension; Hypothyroidism; Intensive Care Units; Male; Mid | 2018 |
[Prevalence and prognostic value of non-thyroidal illness syndrome among critically ill children].
Topics: Adolescent; Child; Child, Preschool; Critical Illness; Euthyroid Sick Syndromes; Female; Humans; Inf | 2019 |
Impact of thyroid function on cystatin C in detecting acute kidney injury: a prospective, observational study.
Topics: Acute Kidney Injury; Adult; APACHE; Area Under Curve; Creatinine; Critical Illness; Cystatin C; Earl | 2019 |
Dynamic neuroendocrine changes in critically ill patients with polytrauma.
Topics: Adult; APACHE; Calcitonin; Calcitonin Gene-Related Peptide; Cohort Studies; Critical Illness; Euthyr | 2015 |
Evaluation of activity of hypothalamo-pituitary-gonadal axis in postmenopausal women suffering from severe acute illness.
Topics: Acute Disease; Aged; Critical Illness; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydr | 2016 |
Two-step thyroid screening strategy in the critical patient.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Follow-Up Studies; | 2016 |
Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits.
Topics: Actins; Animals; Blood Glucose; Body Weight; Critical Illness; Disease Models, Animal; Glucose; Hype | 2010 |
Serum thyroid hormone profile in critically Ill children.
Topics: Case-Control Studies; Child; Child, Preschool; Critical Illness; Euthyroid Sick Syndromes; Humans; I | 2009 |
Increased levothyroxine requirements in critically ill patients with hypothyroidism.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Hypothyroidism; Male; Middle Aged; | 2010 |
The relationship between thyroxine level and short term clinical outcome among sick newborn infants.
Topics: Biomarkers; Birth Weight; Critical Illness; Cross-Sectional Studies; Gestational Age; Hospital Morta | 2011 |
Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study.
Topics: Animals; Constitutive Androstane Receptor; Critical Illness; Disease Models, Animal; Dithiothreitol; | 2012 |
Hypothyroidism and failure to wean in patients receiving prolonged mechanical ventilation at a regional weaning center.
Topics: Comorbidity; Critical Illness; Female; Humans; Hypothyroidism; Male; Respiratory Insufficiency; Retr | 2004 |
Serum thyroid hormones in preterm infants and relationships to indices of severity of intercurrent illness.
Topics: Age Factors; Birth Weight; Cohort Studies; Critical Illness; Fetal Blood; Gestational Age; Humans; I | 2005 |
The effect of a thyroid hormone infusion on vasopressor support in critically ill children with cessation of neurologic function.
Topics: Adolescent; Brain Death; Child; Child, Preschool; Confounding Factors, Epidemiologic; Critical Illne | 2004 |
Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type I deiodinase activity.
Topics: Aged; Brain Damage, Chronic; Cardiovascular Diseases; Cause of Death; Critical Illness; Female; Huma | 2005 |
Serum cortisol and thyroxine concentrations as predictors of death in critically ill puppies with parvoviral diarrhea.
Topics: Animals; Animals, Newborn; Case-Control Studies; Critical Illness; Diarrhea; Dog Diseases; Dogs; Fem | 2007 |
Serum thyrotropin, thyroxine and free thyroxine concentrations as predictors of mortality in critically ill puppies with parvovirus infection: a model for human paediatric critical illness?
Topics: Animals; Case-Control Studies; Critical Illness; Diarrhea; Dogs; Female; Male; Parvoviridae Infectio | 2008 |
Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness.
Topics: Animals; Critical Illness; Disease Models, Animal; Iodide Peroxidase; Kidney; Liver; Male; Molecular | 2008 |
Evaluation of thyroid functions in critically ill infants.
Topics: Adaptation, Physiological; Blood Proteins; C-Reactive Protein; Case-Control Studies; Critical Illnes | 1994 |
Free thyroid hormone puzzle in critical illness.
Topics: Critical Illness; Humans; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins | 1994 |
Heterogeneity in affinities of serum proteins for thyroxine among patients with non-thyroidal illness as indicated by the serum free thyroxine response to serum dilution.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Indicator Dilution Techniques; Mal | 1994 |
Thyrotropin concentration predicts outcome in critical illness.
Topics: Critical Care; Critical Illness; Female; Humans; Hydrocortisone; Male; Middle Aged; Predictive Value | 1993 |
Reduced tissue thyroid hormone levels in fatal illness.
Topics: Adult; Child; Critical Illness; Female; Humans; Male; Middle Aged; Osmolar Concentration; Thyroxine; | 1993 |
Inhibition of thyroxine transport into cultured rat hepatocytes by serum of nonuremic critically ill patients: effects of bilirubin and nonesterified fatty acids.
Topics: Adsorption; Animals; Bilirubin; Biological Transport; Cells, Cultured; Charcoal; Critical Illness; D | 1993 |
Relationship of admission thyroid function tests to outcome in critical illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Critical Care; Critical Illness; Dopamine; F | 1995 |
Prevalence and prognostic relevance of sick euthyroid syndrome in a medical intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; Critical Care; Critical Illness; | 1995 |
Measurement of free triiodothyronine in intensive care patients--comparison of two routine methods.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Humans; Intensive Care Units; Male; Middle Aged; | 1997 |
Thirty-day monitoring of insulin-like growth factors and their binding proteins in intensive care unit patients.
Topics: Adult; Aged; C-Peptide; Critical Illness; Female; Human Growth Hormone; Humans; Hydrocortisone; Insu | 1998 |
Vasopressin pressor effects in critically ill children during evaluation for brain death and organ recovery.
Topics: Adolescent; Blood Pressure; Brain Death; Cardiotonic Agents; Case-Control Studies; Child; Child, Pre | 2000 |
Thyrotropin dysregulation during a non-thyroidal illness: transient hypothalamic hypothyroidism?
Topics: Aged; Aged, 80 and over; Critical Illness; Humans; Hypothalamus; Hypothyroidism; Kinetics; Male; Mid | 2001 |
Protein turnover, lipolysis, and endogenous hormonal secretion in critically ill children.
Topics: C-Peptide; Carbon Radioisotopes; Child, Preschool; Critical Illness; Glycerol; Growth Hormone; Human | 2002 |
Alterations in circadian rhythm of serum thyrotropin in critically ill patients.
Topics: Adult; Aged; Circadian Rhythm; Critical Illness; Female; Humans; Kidney Failure, Chronic; Liver Cirr | 1992 |
Do thyroid function tests independently predict survival in the critically ill?
Topics: Critical Illness; Humans; Prognosis; Radioimmunoassay; Regression Analysis; Risk Factors; Sensitivit | 1992 |