thyroxine has been researched along with Craniopharyngioma in 30 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Craniopharyngioma: A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The major mechanisms that reinforced obesity were hypothalamic damage causing disrupted or impaired sensitivity to feeding-related signals for leptin, insulin, and ghrelin, and reductions in both BMR and physical activity." | 3.76 | Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma. ( Björk, J; Ekman, B; Erfurth, EM; Holmer, H; Popovic, V; Pozarek, G; Wirfält, E, 2010) |
| " Individualized management and accurate hormone replacement dosage for postoperative childhood-onset CP patients are of great importance." | 1.91 | Postoperative hypothalamic-pituitary dysfunction and long-term hormone replacement in patients with childhood-onset craniopharyngioma. ( Bai, RN; Chen, J; Deng, Y; Fan, K; Ge, M; Gong, J; Li, S; Miao, Y; Peng, X; Wei, Y; Wu, D; Wu, Q; Zhao, C, 2023) |
| "Adipsic diabetes insipidus is an infrequent disease which may be associated with craniopharyngioma." | 1.51 | Adipsic diabetes insipidus secondary to craniopharyngioma resection. ( Flórez Romero, A; Millán, HA; Naranjo, JA; Pérez, MA, 2019) |
| "Craniopharyngioma is a rare and mostly benign epithelial tumor of the central nervous system, mostly affecting children." | 1.38 | Treatment of craniopharyngioma in adults: systematic analysis of a 25-year experience. ( Alonso-Vanegas, M; Barges-Coll, J; Gómez-Amador, JL; Lopez-Serna, R; Nathal-Vera, E; Portocarrero-Ortiz, L; Ramos-Peek, M; Revuelta-Gutiérrez, R, 2012) |
| " This study aimed to elucidate the postoperative pituitary hormonal disturbances, and hormone replacement therapy (HRT) time and dosage in children with CP." | 1.35 | Postoperative pituitary hormonal disturbances and hormone replacement therapy time and dosage in children with craniopharyngiomas. ( Li, GM; Shao, P; Sun, XJ, 2008) |
| "Hypopituitarism is a well-known cause of secondary osteoporosis." | 1.33 | High risk of osteopenia and bone derangement in postsurgical patients with craniopharyngiomas, pituitary adenomas and other parasellar lesions. ( Matsuno, A; Okazaki, R; Okinaga, H, 2005) |
| " hGRF was therefore administered at a dosage of 100 micrograms twice a day subcutaneously for three months." | 1.27 | Effects of hGRF treatment of a patient with hGRF deficiency. ( Hizuka, N; Shizume, K; Takano, K; Tanaka, I, 1985) |
| " The mean height velocity attained at the optimal dosage (0." | 1.25 | Medical Research Council of Canada therapeutic trial of human growth hormone: first 5 years of therapy. ( Bailey, JD; Beck, JC; Friesen, H; Guyda, H; Leboeuf, G, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (56.67) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Miao, Y | 1 |
| Fan, K | 1 |
| Peng, X | 1 |
| Li, S | 1 |
| Chen, J | 1 |
| Bai, RN | 1 |
| Wei, Y | 1 |
| Deng, Y | 1 |
| Zhao, C | 1 |
| Wu, Q | 1 |
| Ge, M | 1 |
| Gong, J | 1 |
| Wu, D | 1 |
| Pérez, MA | 1 |
| Millán, HA | 1 |
| Naranjo, JA | 1 |
| Flórez Romero, A | 1 |
| Li, GM | 1 |
| Sun, XJ | 1 |
| Shao, P | 1 |
| Trivin, C | 1 |
| Busiah, K | 1 |
| Mahlaoui, N | 1 |
| Recasens, C | 1 |
| Souberbielle, JC | 1 |
| Zerah, M | 1 |
| Sainte-Rose, C | 1 |
| Brauner, R | 1 |
| Holmer, H | 1 |
| Pozarek, G | 1 |
| Wirfält, E | 1 |
| Popovic, V | 1 |
| Ekman, B | 1 |
| Björk, J | 1 |
| Erfurth, EM | 1 |
| Lopez-Serna, R | 1 |
| Gómez-Amador, JL | 1 |
| Barges-Coll, J | 1 |
| Nathal-Vera, E | 1 |
| Revuelta-Gutiérrez, R | 1 |
| Alonso-Vanegas, M | 1 |
| Ramos-Peek, M | 1 |
| Portocarrero-Ortiz, L | 1 |
| Okinaga, H | 1 |
| Matsuno, A | 1 |
| Okazaki, R | 1 |
| Newns, GH | 1 |
| Pavía, C | 1 |
| Webb, S | 1 |
| Ferrer, I | 1 |
| Martín, MR | 1 |
| Valls, C | 1 |
| Palou, A | 1 |
| Paja, M | 1 |
| Lucas, T | 1 |
| García-Uría, J | 1 |
| Salamé, F | 1 |
| Barceló, B | 1 |
| Estrada, J | 1 |
| Curtis, J | 1 |
| Daneman, D | 1 |
| Hoffman, HJ | 1 |
| Ehrlich, RM | 1 |
| Volz, J | 1 |
| Heinrich, U | 1 |
| Volz-Köster, S | 1 |
| Guyda, H | 1 |
| Friesen, H | 1 |
| Bailey, JD | 1 |
| Leboeuf, G | 1 |
| Beck, JC | 1 |
| Lippe, BM | 1 |
| Van Herle, AJ | 1 |
| LaFranchi, SH | 1 |
| Uller, RP | 1 |
| Lavin, N | 1 |
| Kaplan, SA | 1 |
| Hesse, V | 1 |
| Jenkins, JS | 1 |
| Gilbert, CJ | 1 |
| Ang, V | 1 |
| Rivarola, MA | 1 |
| Mendilaharzu, H | 1 |
| Warman, M | 1 |
| Belgorosky, A | 1 |
| Iorcansky, S | 1 |
| Castellano, M | 1 |
| Caresana, A | 1 |
| Chaler, E | 1 |
| Maceiras, M | 1 |
| Kanev, PM | 1 |
| Lefebvre, JF | 1 |
| Mauseth, RS | 1 |
| Berger, MS | 1 |
| Hiett, AK | 1 |
| Barton, JR | 1 |
| Eskildsen, PC | 1 |
| Kruse, A | 1 |
| Kirkegaard, C | 1 |
| Takano, K | 1 |
| Hizuka, N | 1 |
| Tanaka, I | 1 |
| Shizume, K | 1 |
| Kern, PA | 1 |
| Robbins, RJ | 1 |
| Bichet, D | 1 |
| Berl, T | 1 |
| Verbalis, JG | 1 |
| Webster, B | 1 |
| Bain, J | 1 |
| Otsuki, M | 1 |
| Mori, H | 1 |
| Baba, S | 1 |
| Hiroshige, N | 1 |
| Laron, Z | 1 |
| Karp, M | 1 |
| Pertzela, A | 1 |
| Frankel, J | 1 |
| Gual, C | 1 |
| Kastin, AJ | 1 |
| Schally, AV | 1 |
| Haigler, ED | 1 |
| Pittman, JA | 1 |
| Hershman, JM | 1 |
| Baugh, CM | 1 |
| Tanner, JM | 1 |
| Whitehouse, RH | 1 |
| Hughes, PC | 1 |
| Vince, FP | 1 |
| Richner, K | 1 |
| Schwenk, A | 1 |
| Geisen, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Thyrotropin Releasing Hormone in Patients With Thyroid or Pituitary Abnormalities[NCT00054756] | Phase 2 | 96 participants (Actual) | Interventional | 2003-02-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Serum TSH Levels in Response to TRH Administration (NCT00054756)
Timeframe: 180 minutes from infusion
| Intervention | mcIU/mL (Mean) |
|---|---|
| Thyrotropin Releasing Hormone | 11.47 |
2 reviews available for thyroxine and Craniopharyngioma
| Article | Year |
|---|---|
[Endocrine dwarfism. 2. Treatment of hypothalamo-hypophyseal dwarfism and of constitutional dwarfism with postponement of puberty].
Topics: Adrenal Cortex Hormones; Age Factors; Child; Craniopharyngioma; Dwarfism; Dwarfism, Pituitary; Femal | 1975 |
Clinical experience with hypothalamic releasing hormones. 1. Thyrotropin-releasing hormone.
Topics: Acromegaly; Adult; Amenorrhea; Craniopharyngioma; Dwarfism, Pituitary; Female; Humans; Hyperthyroidi | 1972 |
3 trials available for thyroxine and Craniopharyngioma
| Article | Year |
|---|---|
Antidiuretic effect and complications of chlorpropamide therapy in diabetes insipidus.
Topics: Adolescent; Adult; Chlorpropamide; Clinical Trials as Topic; Craniopharyngioma; Diabetes Insipidus; | 1970 |
ACTH deficiency in children and adolescents (clinical and psychological aspects).
Topics: Adolescent; Adrenocorticotropic Hormone; Child; Clinical Trials as Topic; Craniopharyngioma; Female; | 1970 |
Direct evaluation of pituitary thyrotopin reserve utilizing synthetic thyrotopin releasing hormone.
Topics: Clinical Trials as Topic; Craniopharyngioma; Dexamethasone; Female; Humans; Hyperthyroidism; Hypothy | 1971 |
25 other studies available for thyroxine and Craniopharyngioma
| Article | Year |
|---|---|
Postoperative hypothalamic-pituitary dysfunction and long-term hormone replacement in patients with childhood-onset craniopharyngioma.
Topics: Child; Craniopharyngioma; Deamino Arginine Vasopressin; Hormone Replacement Therapy; Humans; Hydroco | 2023 |
Adipsic diabetes insipidus secondary to craniopharyngioma resection.
Topics: Antidiuretic Agents; Craniopharyngioma; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Hu | 2019 |
Postoperative pituitary hormonal disturbances and hormone replacement therapy time and dosage in children with craniopharyngiomas.
Topics: Adolescent; Child; Craniopharyngioma; Female; Hormone Replacement Therapy; Human Growth Hormone; Hum | 2008 |
Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Craniopharyngioma; Female; Ghrelin; Homeostasis; | 2009 |
Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma.
Topics: Adolescent; Adult; Age of Onset; Androgens; Child; Craniopharyngioma; Energy Intake; Energy Metaboli | 2010 |
Treatment of craniopharyngioma in adults: systematic analysis of a 25-year experience.
Topics: Adolescent; Adult; Aged; Craniopharyngioma; Female; Humans; Hypothalamo-Hypophyseal System; Kaplan-M | 2012 |
High risk of osteopenia and bone derangement in postsurgical patients with craniopharyngiomas, pituitary adenomas and other parasellar lesions.
Topics: Adolescent; Adult; Aged; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Child; Collagen; C | 2005 |
Hypopituitary dwarfism.
Topics: Adolescent; Adult; Child; Child, Preschool; Cortisone; Craniopharyngioma; Dwarfism, Pituitary; Growt | 1967 |
[Tertiary hypothyroidism in idiopathic and acquired adeno-pituitary insufficiency].
Topics: Adolescent; Child; Child, Preschool; Craniopharyngioma; Female; Humans; Hypothyroidism; Male; Pituit | 1983 |
Hypothalamic-pituitary dysfunction in patients with craniopharyngioma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Craniopharyngioma; Female; Gonadotropin-Releasing | 1995 |
The endocrine outcome after surgical removal of craniopharyngiomas.
Topics: Adolescent; Body Height; Body Weight; Child; Child, Preschool; Combined Modality Therapy; Craniophar | 1994 |
Conception and spontaneous delivery after total hypophysectomy.
Topics: Adult; Craniopharyngioma; Deamino Arginine Vasopressin; Estrogen Replacement Therapy; Female; Hemost | 2002 |
Medical Research Council of Canada therapeutic trial of human growth hormone: first 5 years of therapy.
Topics: Adolescent; Age Determination by Skeleton; Antibodies; Body Height; Brain Neoplasms; Canada; Child; | 1975 |
Reversible hypothyroidism in growth hormone-deficient children treated with human growth hormone.
Topics: Age Determination by Skeleton; Body Height; Craniopharyngioma; Diabetes Insipidus; Dwarfism, Pituita | 1975 |
Hypothalamic-pituitary function in patients with craniopharyngiomas.
Topics: Adolescent; Adult; Child; Craniopharyngioma; Female; Gonadotropin-Releasing Hormone; Gonadotropins, | 1976 |
Endocrine disorders in 66 suprasellar and pineal tumors of patients with prepubertal and pubertal ages.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Craniopharyngioma; Dysgerminoma; Endocrine Sys | 1992 |
Growth hormone deficiency following radiation therapy of primary brain tumors in children.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Craniopharyngioma; Ependymoma; Female; Growth | 1991 |
Diabetes insipidus associated with craniopharyngioma in pregnancy.
Topics: Adult; Combined Modality Therapy; Craniopharyngioma; Deamino Arginine Vasopressin; Diabetes Insipidu | 1990 |
The pituitary-thyroid axis in patients with pituitary disorders.
Topics: Adenoma; Adult; Aged; Craniopharyngioma; Euthyroid Sick Syndromes; Female; Follow-Up Studies; Humans | 1989 |
Effects of hGRF treatment of a patient with hGRF deficiency.
Topics: Child; Craniopharyngioma; Dwarfism, Pituitary; Female; Growth Hormone-Releasing Hormone; Humans; Hyd | 1985 |
Syndrome of inappropriate antidiuresis in the absence of arginine vasopressin.
Topics: Adult; Arginine Vasopressin; Bromocriptine; Craniopharyngioma; Growth Hormone; Humans; Hydrocortison | 1986 |
Effect of synthetic thyrotrophin-releasing factor on pituitary TSH secretion in normal subjects and patients with hypothalamic-pituitary disorders.
Topics: Adenoma, Chromophobe; Adolescent; Adult; Aged; Craniopharyngioma; Dose-Response Relationship, Drug; | 1973 |
Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints.
Topics: Adolescent; Adult; Age Factors; Androgens; Anthropometry; Birth Weight; Body Height; Child; Child, P | 1971 |
[Diabetes insipidus occultus. A case of diabetes insipidus occultus hypersalemicus following surgery for craniopharyngioma with acute progressive hypernatremia, hyperosmolar coma and hypokalemic paralysis].
Topics: Acetates; Acute Disease; Adult; Chlorides; Coma; Cortisone; Craniopharyngioma; Diabetes Insipidus; D | 1970 |
[Therapy of hypophyseal dwarfism].
Topics: Adolescent; Adult; Antibodies; Cortisone; Craniopharyngioma; Dwarfism, Pituitary; Female; Growth; Gr | 1970 |