thyroxine has been researched along with Craniofacial Abnormalities in 3 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heterozygous mutations in the thyroid hormone receptor alpha (THRA) gene cause resistance to thyroid hormone alpha (RTHα), a disease characterized by variable manifestations reminiscent of untreated congenital hypothyroidism but a raised triiodothyronine/thyroxine ratio and normal thyrotropin levels." | 3.85 | In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish. ( Carra, S; Cotelli, F; Marelli, F; Persani, L; Rurale, G, 2017) |
| "Craniofacial abnormalities including: microcephaly, underdeveloped maxilla, micrognathia, high arched palate, malocclusion, down-slanting palpebral fissures, thick eyelashes and full eyebrows." | 1.42 | Rubinstein-Taybi Syndrome in a 19-years old boy. ( Przedborska, A; Raczkowski, JW; Wilmańska, I; Zwierzchowski, TJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fetter, E | 1 |
| Baldauf, L | 1 |
| Da Fonte, DF | 1 |
| Ortmann, J | 1 |
| Scholz, S | 1 |
| Zwierzchowski, TJ | 1 |
| Przedborska, A | 1 |
| Wilmańska, I | 1 |
| Raczkowski, JW | 1 |
| Marelli, F | 1 |
| Carra, S | 1 |
| Rurale, G | 1 |
| Cotelli, F | 1 |
| Persani, L | 1 |
3 other studies available for thyroxine and Craniofacial Abnormalities
| Article | Year |
|---|---|
Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos.
Topics: Animals; Antithyroid Agents; Craniofacial Abnormalities; Embryo, Nonmammalian; Gene Expression Regul | 2015 |
Rubinstein-Taybi Syndrome in a 19-years old boy.
Topics: Abnormalities, Multiple; Craniofacial Abnormalities; CREB-Binding Protein; Foot Deformities; Hand De | 2015 |
In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish.
Topics: Anemia; Animals; Animals, Genetically Modified; Brain Edema; Congenital Hypothyroidism; Craniofacial | 2017 |