Page last updated: 2024-11-06

thyroxine and Constipation

thyroxine has been researched along with Constipation in 19 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.

Research Excerpts

ExcerptRelevanceReference
"We demonstrated that constipation was ameliorated, neuromotor development of some children was improved, and creatine kinase levels were diminished with levothyroxine treatment in patients with RTHα, while some features including anemia did not resolve."4.31Long-term follow-up results and treatment outcomes of children and adults with resistance to thyroid hormone alpha. ( Çakır, MD; Demir, K; Erbaş, IM; Yener, AS, 2023)
" A total of 231 patients with clinical hypothyroidism during the second trimester of pregnancy and 210 normal pregnant women were enrolled in the lactulose methane-hydrogen breath test."4.12Efficacy evaluation of probiotics combined with prebiotics in patients with clinical hypothyroidism complicated with small intestinal bacterial overgrowth during the second trimester of pregnancy. ( Ban, Y; Cai, Y; Hao, Y; Li, J; Ouyang, Q; Sun, Z; Wang, M; Wang, W; Wu, B; Xu, Y; Zhang, M, 2022)
"Hypothyroidism is diagnosed on the basis of laboratory tests because of the lack of specificity of the typical clinical manifestations."1.62Severe primary hypothyroidism in an apparently asymptomatic 19-year-old woman: a case report. ( Aljenaee, K; Dannan, R; Hajji, S, 2021)
"We report on three cases of autoimmune thyroiditis (AT) in young children who presented with constipation, decreased appetite, and increased hours of sleep."1.39Rare cases of autoimmune hypothyroidism in young children. ( Caiulo, S; Chiumello, G; Di Frenna, M; Tronconi, GM; Vigone, MC; Weber, G, 2013)
"Hypothyroidism has generally been considered a contraindication to surgery."1.27Complications of surgery in hypothyroid patients. ( Daniels, GH; Ladenson, PW; Levin, AA; Ridgway, EC, 1984)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's2 (10.53)18.2507
2000's2 (10.53)29.6817
2010's7 (36.84)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Hao, Y1
Xu, Y1
Ban, Y1
Li, J1
Wu, B1
Ouyang, Q1
Sun, Z1
Zhang, M1
Cai, Y1
Wang, M1
Wang, W1
Erbaş, IM2
Çakır, MD1
Yener, AS1
Demir, K2
Dannan, R1
Hajji, S1
Aljenaee, K1
Konrad, P1
Chojnacki, J1
Kaczka, A1
Pawłowicz, M1
Rudnicki, C1
Chojnacki, C1
Yamaguchi, T1
Hothubo, T1
Morikawa, S1
Nakamura, A1
Mori, T1
Tajima, T1
Haile, H1
Assefa, G1
Tronconi, GM1
Caiulo, S1
Di Frenna, M1
Vigone, MC1
Chiumello, G1
Weber, G1
van Mullem, AA1
Chrysis, D1
Eythimiadou, A1
Chroni, E1
Tsatsoulis, A1
de Rijke, YB1
Visser, WE1
Visser, TJ1
Peeters, RP1
López Úbeda, M1
de Arriba Muñoz, A1
Abenia Usón, P1
Labarta Aizpún, JI1
Vitale, J1
Fesce, E1
Schmidt, G1
Panjwani, S1
Szabo, SD1
Wells, KL1
Ladenson, PW1
Levin, AA1
Ridgway, EC1
Daniels, GH1
Berndt, H1
Grosshans, A1
Rahman, Q1
Haboubi, NY1
Hudson, PR1
Lee, GS1
Shah, IU1
Johansson, H1
Gordon, DL1
Suvanich, S1
Erviti, V1
Schwartz, MA1
Martinez, CJ1
Cole, P1
Petrie, JC1
Bewsher, PD1

Reviews

1 review available for thyroxine and Constipation

ArticleYear
The Clinical Spectrum of Resistance to Thyroid Hormone Alpha in Children and Adults
    Journal of clinical research in pediatric endocrinology, 2021, 02-26, Volume: 13, Issue:1

    Topics: Adult; Autism Spectrum Disorder; Child; Constipation; Developmental Disabilities; Growth Disorders;

2021

Other Studies

18 other studies available for thyroxine and Constipation

ArticleYear
Efficacy evaluation of probiotics combined with prebiotics in patients with clinical hypothyroidism complicated with small intestinal bacterial overgrowth during the second trimester of pregnancy.
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: Apolipoproteins; Apolipoproteins B; C-Reactive Protein; Cholesterol; Constipation; Fatty Acids, None

2022
Long-term follow-up results and treatment outcomes of children and adults with resistance to thyroid hormone alpha.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:9

    Topics: Adult; Anemia; Child; Child, Preschool; Constipation; Creatine Kinase; Follow-Up Studies; Humans; Th

2023
Severe primary hypothyroidism in an apparently asymptomatic 19-year-old woman: a case report.
    Journal of medical case reports, 2021, Mar-03, Volume: 15, Issue:1

    Topics: Alopecia; Appetite; Autoantibodies; Constipation; Depression; Fatigue; Female; Humans; Hypothyroidis

2021
[Thyroid dysfunction in patients with small intestinal bacterial overgrowth].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2018, Jan-23, Volume: 44, Issue:259

    Topics: Adult; Bacteria; Breath Tests; Constipation; Diarrhea; Female; Humans; Intestine, Small; Male; Middl

2018
A Japanese patient with congenital central hypothyroidism caused by a novel IGSF1 mutation.
    Journal of pediatric endocrinology & metabolism : JPEM, 2018, Mar-28, Volume: 31, Issue:3

    Topics: Abdominal Pain; Adolescent; Body Height; Congenital Hypothyroidism; Constipation; Hormone Replacemen

2018
Congenital hypothyroidism with severe hypoganglionosis of the colon in a 10 years old girl, a case report.
    Ethiopian medical journal, 2011, Volume: 49, Issue:4

    Topics: Barium Sulfate; Child; Colon; Colostomy; Congenital Hypothyroidism; Constipation; Enema; Female; Hir

2011
Rare cases of autoimmune hypothyroidism in young children.
    Journal of pediatric endocrinology & metabolism : JPEM, 2013, Volume: 26, Issue:9-10

    Topics: Appetite; Child, Preschool; Constipation; Delayed Diagnosis; Drug Monitoring; Fatigue; Female; Growt

2013
Clinical phenotype of a new type of thyroid hormone resistance caused by a mutation of the TRα1 receptor: consequences of LT4 treatment.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:7

    Topics: Child; Constipation; Drug Resistance; Dyslipidemias; Female; Frameshift Mutation; Heterozygote; Huma

2013
Hypopituitarism: An uncommon cause of developmental delay.
    Neurologia, 2018, Volume: 33, Issue:8

    Topics: Constipation; Female; Humans; Hypopituitarism; Infant; LIM-Homeodomain Proteins; Male; Muscle Hypoto

2018
Forgotten ileus.
    Gastroenterology, 2012, Volume: 142, Issue:3

    Topics: Adult; Autoantibodies; Biomarkers; Chronic Disease; Colonoscopy; Constipation; Gastrointestinal Moti

2012
An unusual presentation of hypothyroidism.
    Australian family physician, 2003, Volume: 32, Issue:8

    Topics: Aged; Constipation; Diagnosis, Differential; Female; Humans; Hypothyroidism; Thyroxine

2003
What is your diagnosis? Congenital hypothyroidism.
    Journal of the American Veterinary Medical Association, 2007, Jan-01, Volume: 230, Issue:1

    Topics: Animals; Cat Diseases; Cats; Congenital Hypothyroidism; Constipation; Gastrointestinal Agents; Lactu

2007
Complications of surgery in hypothyroid patients.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adult; Aged; Cholecystectomy; Confusion; Constipation; Coronary Disease; Female; Heart Arrest; Human

1984
[A case from general practice (15): New onset constipation in the elderly].
    Zeitschrift fur arztliche Fortbildung, 1994, Volume: 88, Issue:1

    Topics: Aged; Constipation; Diagnosis, Differential; Female; Humans; Hypothyroidism; Thyroid Function Tests;

1994
The effect of thyroxine on small intestinal motility in the elderly.
    Clinical endocrinology, 1991, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Constipation; Female; Gastrointestinal Transit; Humans; Hypothyroidism; Int

1991
Gastrointestinal motility function related to thyroid activity. An experimental study in the rat.
    Acta chirurgica Scandinavica. Supplementum, 1966, Volume: 359

    Topics: Adrenal Glands; Angiography; Animals; Constipation; Diarrhea; Gastrointestinal Motility; Hyperthyroi

1966
The serum calcium level and its significance in hyperthyroidism: A prospective study.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:1

    Topics: Adult; Age Factors; Calcium; Constipation; Female; Humans; Hypercalcemia; Hyperthyroidism; Male; Mid

1974
Intestinal obstruction and hypothyroidism.
    British medical journal, 1969, Sep-13, Volume: 3, Issue:5671

    Topics: Constipation; Female; Humans; Hypothyroidism; Intestinal Obstruction; Middle Aged; Thyroxine

1969