thyroxine has been researched along with Compensatory Hyperinsulinemia in 22 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect." | 5.34 | Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007) |
| " The fetal growth retardation, hyperleptinemia, hyperinsulinism, and cytokines distortions (transforming growth factor-beta; TGF-β, tumor necrosis factor-alpha; TNF-α, and interferon-γ; IFN-γ) were noticed at examined EDs if compared to the control group." | 3.83 | Gestational dexamethasone alters fetal neuroendocrine axis. ( Ahmed, RG, 2016) |
| "Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes." | 1.46 | Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017) |
| "Insulin sensitivity was measured by intravenous glucose tolerance testing, hyperinsulinemic-euglycemic clamps, and insulin-stimulated insulin receptor and protein kinase B phosphorylation levels in muscle." | 1.35 | High isoflavone soy diet increases insulin secretion without decreasing insulin sensitivity in premenopausal nonhuman primates. ( Flynn, DM; Jones, KL; Kavanagh, K; Shadoan, MK; Wagner, JD; Zhang, L, 2008) |
| "Thyrotoxicosis is known to induce a broad range of changes in carbohydrate metabolism." | 1.35 | Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats. ( Ackermans, MT; Boelen, A; Fliers, E; Kalsbeek, A; Klieverik, LP; Sauerwein, HP, 2008) |
| "Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect." | 1.34 | Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007) |
| "A relationship between hyperinsulinemia and decreased serum sex hormone-binding globulin (SHBG) has been described in adults." | 1.31 | Sex hormone-binding globulin as a marker for hyperinsulinemia and/or insulin resistance in obese children. ( Cañete, R; Gascón, F; Martos, R; Montilla, P; Ríos, R; Ruz, FJ; Valle, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bas, S | 1 |
| Guran, T | 1 |
| Atay, Z | 1 |
| Haliloglu, B | 1 |
| Abalı, S | 1 |
| Turan, S | 1 |
| Bereket, A | 1 |
| Ahmed, RG | 1 |
| Askari, A | 1 |
| Ehrampoush, E | 1 |
| Homayounfar, R | 1 |
| Bahramali, E | 1 |
| Farjam, M | 1 |
| Kavanagh, K | 1 |
| Jones, KL | 1 |
| Zhang, L | 1 |
| Flynn, DM | 1 |
| Shadoan, MK | 1 |
| Wagner, JD | 1 |
| Praveen, EP | 1 |
| Khurana, ML | 1 |
| Kulshreshtha, B | 1 |
| Dwivedi, SN | 1 |
| Prabhakaran, D | 1 |
| Khadgawat, R | 1 |
| Gupta, N | 1 |
| Kumar, G | 1 |
| Ammini, AC | 1 |
| Rochon, C | 1 |
| Tauveron, I | 1 |
| Dejax, C | 1 |
| Benoit, P | 1 |
| Capitan, P | 1 |
| Fabricio, A | 1 |
| Berry, C | 1 |
| Champredon, C | 1 |
| Thieblot, P | 1 |
| Grizard, J | 1 |
| Riis, AL | 1 |
| Hansen, TK | 1 |
| Møller, N | 1 |
| Weeke, J | 1 |
| Jørgensen, JO | 1 |
| LEAK, D | 1 |
| BRUNJES, S | 1 |
| JOHNS, VJ | 1 |
| STARR, P | 1 |
| UTIGER, RD | 1 |
| Velija-Asimi, Z | 1 |
| Karamehic, J | 1 |
| Bhatt, P | 1 |
| Makwana, D | 1 |
| Santani, D | 1 |
| Goyal, R | 1 |
| Klieverik, LP | 1 |
| Sauerwein, HP | 1 |
| Ackermans, MT | 1 |
| Boelen, A | 1 |
| Kalsbeek, A | 1 |
| Fliers, E | 1 |
| Kolodin, VA | 1 |
| Gasilin, VS | 1 |
| Baranov, VA | 1 |
| Antonov, IuS | 1 |
| Dokuchaeva, EA | 1 |
| Brook, CG | 1 |
| Chapa, AM | 1 |
| Fernandez, JM | 1 |
| Thompson, DL | 1 |
| Tempelman, RJ | 1 |
| Berrio, LF | 1 |
| Croom, WJ | 1 |
| Hagler, WM | 1 |
| de L Costello, AM | 1 |
| Pal, DK | 1 |
| Manandhar, DS | 1 |
| Rajbhandari, S | 1 |
| Land, JM | 1 |
| Patel, N | 1 |
| Gascón, F | 1 |
| Valle, M | 1 |
| Martos, R | 1 |
| Ruz, FJ | 1 |
| Ríos, R | 1 |
| Montilla, P | 1 |
| Cañete, R | 1 |
| Chen, AS | 1 |
| Marsh, DJ | 1 |
| Trumbauer, ME | 1 |
| Frazier, EG | 1 |
| Guan, XM | 1 |
| Yu, H | 1 |
| Rosenblum, CI | 1 |
| Vongs, A | 1 |
| Feng, Y | 1 |
| Cao, L | 1 |
| Metzger, JM | 1 |
| Strack, AM | 1 |
| Camacho, RE | 1 |
| Mellin, TN | 1 |
| Nunes, CN | 1 |
| Min, W | 1 |
| Fisher, J | 1 |
| Gopal-Truter, S | 1 |
| MacIntyre, DE | 1 |
| Chen, HY | 1 |
| Van der Ploeg, LH | 1 |
| Kissebah, AH | 1 |
| Schectman, G | 1 |
| Okamoto, H | 1 |
| Hinman, DJ | 1 |
| Griffith, DR | 1 |
| Kreisberg, RA | 1 |
| Owen, WC | 1 |
| Siegal, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Corneal Tomographic Analysis Among Patients With Thyroid Gland Dysfunction.[NCT04433936] | 100 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thyroxine and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Hormones and lipoprotein metabolism.
Topics: Catecholamines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucocortico | 1987 |
[On the regulatory mechanism of kynurenine metabolism in mitochondrial membranes with special reference to the problem of hyperinsulinemia or diabetic state (author's transl)].
Topics: Animals; Diabetes Mellitus; Electron Transport; Female; Flavin-Adenine Dinucleotide; Glucose; Humans | 1974 |
Nutrition and endocrine disease.
Topics: Acromegaly; Adipose Tissue; Adrenal Gland Diseases; Animals; Body Composition; Diabetes Mellitus; En | 1970 |
1 trial available for thyroxine and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Hyperthyroidism is associated with suppressed circulating ghrelin levels.
Topics: Adult; Body Composition; Energy Metabolism; Fasting; Female; Ghrelin; Glucose Clamp Technique; Human | 2003 |
18 other studies available for thyroxine and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Premature pubarche, hyperinsulinemia and hypothyroxinemia: novel manifestations of congenital portosystemic shunts (Abernethy malformation) in children.
Topics: Adolescent; Child; Female; Humans; Hyperinsulinism; Puberty, Precocious; Thyroxine; Vascular Malform | 2015 |
Gestational dexamethasone alters fetal neuroendocrine axis.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Endocrine Disruptors; Female; Fetal Dev | 2016 |
Serum insulin in pathogenesis and treatment of osteoarthritis.
Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression; | 2017 |
High isoflavone soy diet increases insulin secretion without decreasing insulin sensitivity in premenopausal nonhuman primates.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Cholesterol, HDL; Estrogen Receptor Modulators; Fe | 2008 |
Plasma testosterone in adult normoglycaemic men: impact of hyperinsulinaemia.
Topics: Adult; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Humans; Hydroc | 2012 |
Response of glucose disposal to hyperinsulinaemia in human hypothyroidism and hyperthyroidism.
Topics: Adult; Amino Acids; Blood Glucose; Drug Administration Schedule; Female; Glucose; Glucose Clamp Tech | 2003 |
LETTER TO THE EDITOR: EXCESS THYROID MEDICATION AND ADRENAL MEDULLARY RESPONSE TO INSULIN HYPOGLYCEMIA.
Topics: Adrenal Medulla; Epinephrine; Humans; Hyperinsulinism; Hypoglycemia; Hypothyroidism; Insulins; Thyro | 1963 |
RADIOIMMUNOASSAY OF HUMAN PLASMA THYROTROPIN.
Topics: Antigen-Antibody Reactions; Chromatography; Chromatography, Gel; Drug Therapy; Electrophoresis; Huma | 1965 |
The effects of treatment of subclinical hypothyroidism on metabolic control and hyperinsulinemia.
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glucose Intolerance; Glycated Hemoglobin; | 2007 |
Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study.
Topics: Adrenergic beta-Antagonists; Animals; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body | 2007 |
Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats.
Topics: Animals; Autonomic Denervation; Blood Glucose; Glucose; Glucose Clamp Technique; Hyperinsulinism; In | 2008 |
[Role of excessive body weight and hormonal changes in the development of the main types of hyperlipoproteinemia].
Topics: Adrenocortical Hyperfunction; Adult; Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hyperl | 1984 |
Obesity: the fat child.
Topics: Adipose Tissue; Adult; Child; Child Development; Child, Preschool; Diagnosis, Differential; Diet, Re | 1980 |
Endocrine and metabolic response to muscarinic stimulation and inhibition in the ruminant: effects of slaframine.
Topics: Alkaloids; Animals; Blood Glucose; Endocrine Glands; Fatty Acids, Nonesterified; Female; Goat Diseas | 1995 |
Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.
Topics: Age Factors; Blood Glucose; Cross-Sectional Studies; Energy Metabolism; Fatty Acids, Nonesterified; | 2000 |
Sex hormone-binding globulin as a marker for hyperinsulinemia and/or insulin resistance in obese children.
Topics: Biomarkers; Blood Glucose; Body Mass Index; Child; Estradiol; Female; Humans; Hyperinsulinism; Insul | 2000 |
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass.
Topics: Adipose Tissue; Age Factors; alpha-MSH; Animals; Blotting, Southern; Body Temperature; Body Weight; | 2000 |
Effects of ventromedial hypothalamic lesions on thyroid secretion rate in rats.
Topics: Animals; Body Weight; Growth Hormone; Hyperinsulinism; Hypothalamus; Iodine Isotopes; Lipid Metaboli | 1973 |