Page last updated: 2024-11-06

thyroxine and Colonic Neoplasms

thyroxine has been researched along with Colonic Neoplasms in 11 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"In this study, we prepared tetraiodothyroacetic acid (tetrac) conjugated PEG-PLGA polymersomes for the targeted delivery of camptothecin to colon adenocarcinoma."7.85Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo. ( Abnous, K; Alibolandi, M; Farzad, SA; Ramezani, M; Rezvani, R; Taghdisi, SM, 2017)
"Plasma triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were measured in 44 early breast cancer patients, 48 with advanced breast cancer, 20 with cancer of the colon, and 56 healthy women of similar age."7.66Plasma triiodothyronine concentrations in breast cancer. ( Davis, TE; Rose, DP, 1979)
"In this study, we prepared tetraiodothyroacetic acid (tetrac) conjugated PEG-PLGA polymersomes for the targeted delivery of camptothecin to colon adenocarcinoma."3.85Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo. ( Abnous, K; Alibolandi, M; Farzad, SA; Ramezani, M; Rezvani, R; Taghdisi, SM, 2017)
"Plasma triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were measured in 44 early breast cancer patients, 48 with advanced breast cancer, 20 with cancer of the colon, and 56 healthy women of similar age."3.66Plasma triiodothyronine concentrations in breast cancer. ( Davis, TE; Rose, DP, 1979)
"For human breast cancer cells, modeling suggested a higher sensitivity (lower IC50) to the effect on success rate of replication than the effect on rate of growth, whereas the capacity (Imax) was larger for the effect on growth rate."1.37Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system. ( Brown, D; Davis, FB; Davis, PJ; Drusano, GL; Kulawy, R; Landersdorfer, CB; Lim, CU; Lin, C; Lin, HY; Lin, S; London, D; Louie, A; Meng, R; Mousa, SA; Queimado, L; Tang, HY; Van Scoy, B, 2011)
"Plasma T3 levels were reduced in both breast cancer group, but were reduced only in colonic cancer patients with systemic metastases."1.26Plasma thyronine levels in carcinoma of the breast and colon. ( Davis, TE; Rose, DP, 1981)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alibolandi, M1
Rezvani, R1
Farzad, SA1
Taghdisi, SM1
Abnous, K1
Ramezani, M1
Nana, AW1
Chin, YT1
Lin, CY1
Ho, Y1
Bennett, JA1
Shih, YJ1
Chen, YR1
Changou, CA1
Pedersen, JZ1
Incerpi, S1
Liu, LF1
Whang-Peng, J1
Fu, E1
Li, WS1
Mousa, SA2
Lin, HY2
Davis, PJ2
Landersdorfer, CB1
London, D1
Meng, R1
Lim, CU1
Lin, C1
Lin, S1
Tang, HY1
Brown, D1
Van Scoy, B1
Kulawy, R1
Queimado, L1
Drusano, GL1
Louie, A1
Davis, FB1
Youn, JC1
Rhee, Y1
Park, SY1
Kim, WH1
Kim, SJ1
Chung, HC1
Hong, SW1
Lim, SK1
Rose, DP2
Davis, TE2
Turner, JG1
Brownlie, BE1
Sadler, WA1
Arango, A1
Lester, JL1
Martinez, OV1
Malinin, TI1
Zeppa, R1
Iishi, H1
Tatsuta, M1
Baba, M1
Okuda, S1
Taniguchi, H1
Lee, JK1
Gordon, PR1
Stall, GM1
Gilchrest, BA1
Kaplan, MM1
Bellabarba, D1
Inada, M1
Varsano-Aharon, N1
Sterling, K1

Other Studies

11 other studies available for thyroxine and Colonic Neoplasms

ArticleYear
Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Adenocarcinoma; Animals; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Drug Delivery Systems; F

2017
Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer.
    Endocrine-related cancer, 2018, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm

2018
Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system.
    PLoS computational biology, 2011, Feb-03, Volume: 7, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast

2011
Severe hypothyroidism induced by thyroid metastasis of colon adenocarcinoma: a case report and review of the literature.
    Endocrine journal, 2006, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Aged, 80 and over; Colonic Neoplasms; Goiter; Humans; Hypothyroidism; Male; Thyroid

2006
Plasma thyronine levels in carcinoma of the breast and colon.
    Archives of internal medicine, 1981, Volume: 141, Issue:9

    Topics: Adult; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Middle Aged;

1981
Letter: Does T4 toxicosis exist?
    Lancet (London, England), 1975, Feb-15, Volume: 1, Issue:7903

    Topics: Colonic Neoplasms; Female; Humans; Hyperthyroidism; Middle Aged; Neoplasm Metastasis; Thyroid Functi

1975
Bacteriologic and systemic effects of intraoperative segmental bowel preparation with povidone iodine.
    Archives of surgery (Chicago, Ill. : 1960), 1979, Volume: 114, Issue:2

    Topics: Adult; Aged; Bacteria; Carcinoma; Colon; Colonic Diseases; Colonic Neoplasms; Humans; Iodine; Middle

1979
Plasma triiodothyronine concentrations in breast cancer.
    Cancer, 1979, Volume: 43, Issue:4

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Middle Aged; Thyroid

1979
Enhancement by thyroxine of experimental carcinogenesis induced in rat colon by azoxymethane.
    International journal of cancer, 1992, Apr-01, Volume: 50, Issue:6

    Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogens; Colo

1992
Phenolic and tyrosyl ring iodothyronine deiodination by the Caco-2 human colon carcinoma cell line.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:12

    Topics: Carcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Absorption; Iodine; Kinetics;

1989
Thyroxine transport and turnover in major nonthyroidal illness.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Biological Transport; Blood Proteins; Carcinoma; Carcinoma, Bronchogeni

1968