Compounds > thyroxine
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thyroxine and Coagulation Disorders, Blood

thyroxine has been researched along with Coagulation Disorders, Blood in 5 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"We analyzed the impact of levothyroxine treatment on lipid parameters, fibrinogen, platelet count, D-dimers, alpha2 antiplasmin activity, plasminogen activity, tissue plasminogen activator antigen (t-PA Ag), plasminogen activator inhibitor type 1 antigen (PAI-1 Ag) and coagulation factors (factor VIII coagulant, von Willebrand factor antigen, von Willebrand factor and factor IX) in 23 patients with severe hypothyroidism (TSH level > 50 mU/ I)."9.11Effect of levothyroxine replacement therapy on coagulation and fibrinolysis in severe hypothyroidism. ( Ankri, A; Bruckert, E; Chadarevian, R; Chapman, J; Giral, P; Jublanc, C; Leenhardt, L; Turpin, G, 2005)
"We analyzed the impact of levothyroxine treatment on lipid parameters, fibrinogen, platelet count, D-dimers, alpha2 antiplasmin activity, plasminogen activity, tissue plasminogen activator antigen (t-PA Ag), plasminogen activator inhibitor type 1 antigen (PAI-1 Ag) and coagulation factors (factor VIII coagulant, von Willebrand factor antigen, von Willebrand factor and factor IX) in 23 patients with severe hypothyroidism (TSH level > 50 mU/ I)."5.11Effect of levothyroxine replacement therapy on coagulation and fibrinolysis in severe hypothyroidism. ( Ankri, A; Bruckert, E; Chadarevian, R; Chapman, J; Giral, P; Jublanc, C; Leenhardt, L; Turpin, G, 2005)
"Controversy remains as to the risk of cardiovascular disease (CVD) associated with subclinical hypothyroidism (SCH), defined as an increased serum thyrotropin (TSH) concentration with normal free thyroxine and triiodothyronine levels."4.84Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence? ( Duntas, LH; Wartofsky, L, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehsanzadeh-Cheemeh, P1
Thompson, M1
Miller, M1
Chadarevian, R1
Jublanc, C1
Bruckert, E1
Giral, P1
Ankri, A1
Leenhardt, L1
Chapman, J1
Turpin, G1
Duntas, LH1
Wartofsky, L1
Campanini, M1
Saglietti, G1
Zaccala, G1
Occhipinti, P1
Cardano, S1
Monteverde, A1
Hedley, AJ1

Reviews

3 reviews available for thyroxine and Coagulation Disorders, Blood

ArticleYear
Subclinical hypothyroidism and homeostatic disturbances: case report and literature review.
    Recent patents on endocrine, metabolic & immune drug discovery, 2012, Volume: 6, Issue:2

    Topics: Adolescent; Blood Coagulation Disorders; Female; Hemostasis; Humans; Hypothyroidism; Thyroid Hormone

2012
Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence?
    Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation Disorders; Cardiovascular Diseases; Humans; Hyperc

2007
Myxoedema.
    The Practitioner, 1972, Volume: 208, Issue:245

    Topics: Anemia; Blood Coagulation Disorders; Central Nervous System Diseases; Electrocardiography; Female; G

1972

Trials

1 trial available for thyroxine and Coagulation Disorders, Blood

ArticleYear
Effect of levothyroxine replacement therapy on coagulation and fibrinolysis in severe hypothyroidism.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:5

    Topics: Adult; Blood Coagulation; Blood Coagulation Disorders; Female; Fibrinolysis; Humans; Hypothyroidism;

2005

Other Studies

1 other study available for thyroxine and Coagulation Disorders, Blood

ArticleYear
[Behavior of thyroid hormones in chronic hepatopathies].
    Recenti progressi in medicina, 1986, Volume: 77, Issue:9

    Topics: Adult; Aged; Blood Coagulation Disorders; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosi

1986