thyroxine has been researched along with Cirrhosis in 26 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sacubitril/valsartan (LCZ696) is a new combined drug that has shown promise for the treatment of hyperthyroidism-associated heart failure; however, the underlying molecular mechanisms, including the contributions of epigenetic regulation, remain unclear." | 8.12 | Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways. ( Abdullah, DM; Alsemeh, AE; Khamis, T, 2022) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 7.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "The present study assessed the possible involvement of the renin-angiotensin system (RAS) and the sympathetic nervous system (SNS) in thyroxine (T4)-induced cardiac hypertrophy." | 7.72 | Thyroxine-induced cardiac hypertrophy: influence of adrenergic nervous system versus renin-angiotensin system on myocyte remodeling. ( Barreto-Chaves, ML; Benvenuti, LA; Carneiro-Ramos, MS; Hu, LW; Liberti, EA, 2003) |
| "Grades 3 to 4 hepatic encephalopathy (advanced HE), also termed brain failure, is an organ failure that defines acute-on-chronic liver failure." | 5.91 | Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort. ( Bajaj, JS; Fagan, A; Garcia-Tsao, G; Kamath, PS; Lai, JC; McGeorge, S; O'Leary, JG; Reddy, KR; Subramanian, RM; Tandon, P; Thacker, LR; Thuluvath, P; Vargas, HE; Wong, F, 2023) |
| "Presently, the standard of care for prolactinomas, a type of pituitary adenoma, is dopaminergic agents such as bromocriptine and cabergoline." | 5.46 | Cabergoline-induced fibrosis of prolactinomas: a neurosurgical perspective. ( Chia, YY; Goh, GH; Mohan, N; Teo, K; Ting, E; Yeo, TT, 2017) |
| " Sacubitril/valsartan (LCZ696) is a new combined drug that has shown promise for the treatment of hyperthyroidism-associated heart failure; however, the underlying molecular mechanisms, including the contributions of epigenetic regulation, remain unclear." | 4.12 | Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways. ( Abdullah, DM; Alsemeh, AE; Khamis, T, 2022) |
| "The novel peptides markedly reduced thyroid size, serum thyroxine levels, retro-orbital fibrosis, and tachycardia in Ad-TSHR289-immunized mice." | 3.91 | Therapeutic Effects of Short Cyclic and Combined Epitope Peptides in a Long-Term Model of Graves' Disease and Orbitopathy. ( Faßbender, J; Holthoff, HP; Li, Z; Ungerer, M, 2019) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 3.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "The present study assessed the possible involvement of the renin-angiotensin system (RAS) and the sympathetic nervous system (SNS) in thyroxine (T4)-induced cardiac hypertrophy." | 3.72 | Thyroxine-induced cardiac hypertrophy: influence of adrenergic nervous system versus renin-angiotensin system on myocyte remodeling. ( Barreto-Chaves, ML; Benvenuti, LA; Carneiro-Ramos, MS; Hu, LW; Liberti, EA, 2003) |
| "204 patients with a single or dominant 'cold' thyroid nodule were treated with l-thyroxine, 150-250 micrograms/d, for 4 to 12 months." | 3.68 | The outcome of benign thyroid nodules correlates with the findings of fine needle biopsy. ( Katsouyanni, K; Kitsopanides, J; Koutras, DA; Tseleni-Balafouta, S, 1991) |
| "Grades 3 to 4 hepatic encephalopathy (advanced HE), also termed brain failure, is an organ failure that defines acute-on-chronic liver failure." | 1.91 | Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort. ( Bajaj, JS; Fagan, A; Garcia-Tsao, G; Kamath, PS; Lai, JC; McGeorge, S; O'Leary, JG; Reddy, KR; Subramanian, RM; Tandon, P; Thacker, LR; Thuluvath, P; Vargas, HE; Wong, F, 2023) |
| "In sufferers with nonalcoholic fatty liver disease (NAFLD), the differences of thyroid associated hormones and neutrophil to lymphocyte ratio (NLR) in different liver pathological groups have been compared." | 1.72 | Clinical value of thyroid related hormones combined with neutrophil to lymphocyte ratio in patients with nonalcoholic fatty liver disease. ( Chu, W; Feng, J; Li, P; Liu, L; Liu, Y; Mi, Y; Niu, B; Wu, X; Zhang, P, 2022) |
| "Presently, the standard of care for prolactinomas, a type of pituitary adenoma, is dopaminergic agents such as bromocriptine and cabergoline." | 1.46 | Cabergoline-induced fibrosis of prolactinomas: a neurosurgical perspective. ( Chia, YY; Goh, GH; Mohan, N; Teo, K; Ting, E; Yeo, TT, 2017) |
| "Treatment with ivabradine significantly reduced HR and LVESD, improved SRcirc, S long and SRlong in the T4 group, and the average I Ca,L density at 0 mV in T4-Iva groups (9." | 1.39 | Heart rate reduction with ivabradine prevents thyroid hormone-induced cardiac remodeling in rat. ( Cho, KI; Han, J; Kim, BH; Kim, IJ; Kim, JY; Kim, N; Kim, SM, 2013) |
| "Granulomatous experimental autoimmune thyroiditis (G-EAT) is induced by mouse thyroglobulin (MTg)-sensitized splenocytes activated with MTg and interleukin (IL)-12." | 1.36 | Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice. ( Braley-Mullen, H; Chen, K; Fang, Y; Jackson, DA; Sharp, GC, 2010) |
| "He was diagnosed with Graves' disease (GD) and central diabetes insipidus (CDI)." | 1.36 | Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo-neurohypophysitis in a patient treated for Graves' disease. ( Komatsu, M; Nishio, S; Sato, A; Uehara, T; Yamazaki, M, 2010) |
| "Induction of cardiac hypertrophy revealed a marked protective effect caused by the expression of the kallikrein transgene, evidenced by the significantly reduced cardiac weight gain and the lower enhancement in the cardiac expression of atrial natriuretic peptide and collagen III, markers for hypertrophy and fibrosis, respectively." | 1.35 | Protective actions of human tissue kallikrein gene in transgenic rat hearts. ( Bader, M; Nascimento, JW; Pesquero, JB; Silva, JA; Silva, MR, 2008) |
| "Fibrosis was confirmed by staining for collagen and alpha smooth-muscle actin, a marker of myofibroblasts." | 1.31 | Characterization of thyroid fibrosis in a murine model of granulomatous experimental autoimmune thyroiditis. ( Braley-Mullen, H; Chen, K; Sharp, GC; Wei, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Khaleel, EF | 1 |
| Bajaj, JS | 1 |
| Tandon, P | 1 |
| O'Leary, JG | 1 |
| Reddy, KR | 1 |
| Garcia-Tsao, G | 1 |
| Thuluvath, P | 1 |
| Lai, JC | 1 |
| Subramanian, RM | 1 |
| Vargas, HE | 1 |
| Wong, F | 1 |
| Fagan, A | 1 |
| McGeorge, S | 1 |
| Thacker, LR | 1 |
| Kamath, PS | 1 |
| Khamis, T | 1 |
| Alsemeh, AE | 1 |
| Abdullah, DM | 1 |
| Li, P | 1 |
| Liu, L | 1 |
| Niu, B | 1 |
| Mi, Y | 1 |
| Liu, Y | 1 |
| Feng, J | 1 |
| Zhang, P | 1 |
| Wu, X | 1 |
| Chu, W | 1 |
| Mohan, N | 1 |
| Chia, YY | 1 |
| Goh, GH | 1 |
| Ting, E | 1 |
| Teo, K | 1 |
| Yeo, TT | 1 |
| Teixeira, RB | 1 |
| Zimmer, A | 1 |
| de Castro, AL | 1 |
| Carraro, CC | 1 |
| Casali, KR | 1 |
| Dias, IGM | 1 |
| Godoy, AEG | 1 |
| Litvin, IE | 1 |
| Belló-Klein, A | 1 |
| da Rosa Araujo, AS | 1 |
| Zhang, K | 1 |
| Tang, YD | 1 |
| Zhang, Y | 1 |
| Ojamaa, K | 1 |
| Li, Y | 2 |
| Saini, AS | 1 |
| Carrillo-Sepulveda, MA | 1 |
| Rajagopalan, V | 1 |
| Gerdes, AM | 1 |
| Faßbender, J | 1 |
| Holthoff, HP | 1 |
| Li, Z | 1 |
| Ungerer, M | 1 |
| Ellis, JS | 1 |
| Hong, SH | 1 |
| Zaghouani, H | 1 |
| Braley-Mullen, H | 3 |
| Bagnato, G | 2 |
| Bitto, A | 1 |
| Irrera, N | 1 |
| Pizzino, G | 1 |
| Sangari, D | 1 |
| Cinquegrani, M | 1 |
| Roberts, W | 1 |
| Atteritano, M | 1 |
| Altavilla, D | 1 |
| Squadrito, F | 1 |
| Saitta, A | 1 |
| Farhat, A | 1 |
| Buick, JK | 1 |
| Williams, A | 1 |
| Yauk, CL | 1 |
| O'Brien, JM | 1 |
| Crump, D | 1 |
| Williams, KL | 1 |
| Chiu, S | 1 |
| Kennedy, SW | 1 |
| Hajje, G | 1 |
| Saliba, Y | 1 |
| Itani, T | 1 |
| Moubarak, M | 1 |
| Aftimos, G | 1 |
| Farès, N | 1 |
| Fang, Y | 1 |
| Chen, K | 2 |
| Jackson, DA | 1 |
| Sharp, GC | 2 |
| Nishihara, E | 1 |
| Hirokawa, M | 1 |
| Taniguchi, E | 1 |
| Miyauchi, A | 1 |
| Kakudo, K | 1 |
| Yamazaki, M | 1 |
| Sato, A | 1 |
| Nishio, S | 1 |
| Uehara, T | 1 |
| Komatsu, M | 1 |
| Elnakish, MT | 1 |
| Hassona, MD | 1 |
| Alhaj, MA | 1 |
| Moldovan, L | 1 |
| Janssen, PM | 1 |
| Khan, M | 1 |
| Hassanain, HH | 1 |
| Kim, BH | 1 |
| Cho, KI | 1 |
| Kim, SM | 1 |
| Kim, N | 1 |
| Han, J | 1 |
| Kim, JY | 1 |
| Kim, IJ | 1 |
| Hu, LW | 1 |
| Benvenuti, LA | 1 |
| Liberti, EA | 1 |
| Carneiro-Ramos, MS | 1 |
| Barreto-Chaves, ML | 1 |
| Silva, JA | 1 |
| Silva, MR | 1 |
| Nascimento, JW | 1 |
| Bader, M | 1 |
| Pesquero, JB | 1 |
| Robert, V | 1 |
| Silvestre, JS | 1 |
| Charlemagne, D | 1 |
| Sabri, A | 1 |
| Trouvé, P | 1 |
| Wassef, M | 1 |
| Swynghedauw, B | 1 |
| Delcayre, C | 1 |
| Brady, OH | 1 |
| Hehir, DJ | 1 |
| Heffernan, SJ | 1 |
| Vaidya, B | 1 |
| Coulthard, A | 1 |
| Goonetilleke, A | 1 |
| Burn, DJ | 1 |
| James, RA | 1 |
| Kendall-Taylor, P | 1 |
| Wei, Y | 1 |
| Yao, J | 2 |
| Eghbali, M | 2 |
| Tseleni-Balafouta, S | 1 |
| Katsouyanni, K | 1 |
| Kitsopanides, J | 1 |
| Koutras, DA | 1 |
1 review available for thyroxine and Cirrhosis
| Article | Year |
|---|---|
Riedel's thyroiditis--case report and literature review.
Topics: Combined Modality Therapy; Drug Therapy, Combination; Female; Fibrosis; Humans; Hydrocortisone; Midd | 1994 |
25 other studies available for thyroxine and Cirrhosis
| Article | Year |
|---|---|
l-Thyroxine induces left ventricular remodeling and fibrosis in rats by upregulating miR-21 in a reactive oxygen-dependent mechanism: a protective role of
Topics: Acetylcysteine; Actins; Animals; Antagomirs; Collagen; Fibrosis; Glutathione; Inflammasomes; Interle | 2022 |
Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort.
Topics: Fibrosis; Hepatic Encephalopathy; Humans; Inpatients; Liver Cirrhosis; Prospective Studies; Thyroxin | 2023 |
Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Autophagy; Biphenyl Compounds; Cardiomega | 2022 |
Clinical value of thyroid related hormones combined with neutrophil to lymphocyte ratio in patients with nonalcoholic fatty liver disease.
Topics: Fibrosis; Humans; Lymphocytes; Neutrophils; Non-alcoholic Fatty Liver Disease; Thyroid Gland; Thyroi | 2022 |
Cabergoline-induced fibrosis of prolactinomas: a neurosurgical perspective.
Topics: Adult; Antineoplastic Agents; Cabergoline; Combined Modality Therapy; Diagnosis, Differential; Dopam | 2017 |
Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats.
Topics: Animals; Echocardiography; Exercise Therapy; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardi | 2018 |
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele | 2018 |
Therapeutic Effects of Short Cyclic and Combined Epitope Peptides in a Long-Term Model of Graves' Disease and Orbitopathy.
Topics: Adenoviridae; Animals; Disease Models, Animal; Epitopes; Female; Fibrosis; Graves Ophthalmopathy; HE | 2019 |
Reduced effectiveness of CD4+Foxp3+ regulatory T cells in CD28-deficient NOD.H-2h4 mice leads to increased severity of spontaneous autoimmune thyroiditis.
Topics: Animals; Autoantibodies; B-Lymphocytes; CD28 Antigens; CD4 Antigens; Fibrosis; Forkhead Transcriptio | 2013 |
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal | 2013 |
Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos.
Topics: Animals; Apolipoproteins E; Bile Acids and Salts; Chick Embryo; Cholesterol; Dose-Response Relations | 2014 |
Hypothyroidism and its rapid correction alter cardiac remodeling.
Topics: Animals; Atrial Remodeling; Cytokines; Fibrosis; Heart; Hypothyroidism; Male; Myocardium; Propylthio | 2014 |
Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice.
Topics: Animals; Antibodies, Monoclonal; Cell Count; Cell Movement; Chemokine CCL11; Chemokine CXCL1; Diseas | 2010 |
Distinct clinical, serological, and sonographic characteristics of hashimoto's thyroiditis based with and without IgG4-positive plasma cells.
Topics: Adult; Aged; Autoantibodies; Disease Progression; Female; Fibrosis; Hashimoto Disease; Humans; Immun | 2010 |
Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo-neurohypophysitis in a patient treated for Graves' disease.
Topics: Arginine Vasopressin; Deamino Arginine Vasopressin; Diabetes Insipidus, Neurogenic; Fibrosis; Graves | 2010 |
Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.
Topics: Animals; Apoptosis; Blotting, Western; Carbazoles; Cardiomegaly; Cardiomyopathies; Carvedilol; Echoc | 2012 |
Heart rate reduction with ivabradine prevents thyroid hormone-induced cardiac remodeling in rat.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Calcium Signaling; Disease Models, Animal; Fibrosis; | 2013 |
Thyroxine-induced cardiac hypertrophy: influence of adrenergic nervous system versus renin-angiotensin system on myocyte remodeling.
Topics: Animals; Blood Pressure; Cardiomegaly; Connective Tissue; Fibrosis; Heart Rate; Male; Myocytes, Card | 2003 |
Protective actions of human tissue kallikrein gene in transgenic rat hearts.
Topics: Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Cardiomegaly; Collagen Type III; | 2008 |
Biological determinants of aldosterone-induced cardiac fibrosis in rats.
Topics: Aldosterone; Animals; Blotting, Northern; Collagen; Fibrosis; Heart; Histocytochemistry; Hypertensio | 1995 |
Cerebral venous sinus thrombosis: a late sequel of invasive fibrous thyroiditis.
Topics: Cerebral Veins; Female; Fibrosis; Heparin; Humans; Jugular Veins; Magnetic Resonance Angiography; Ma | 1998 |
Characterization of thyroid fibrosis in a murine model of granulomatous experimental autoimmune thyroiditis.
Topics: Actins; Adoptive Transfer; Animals; Antibodies, Monoclonal; Autoimmune Diseases; Biomarkers; CD4-Pos | 2000 |
Decreased collagen gene expression and absence of fibrosis in thyroid hormone-induced myocardial hypertrophy. Response of cardiac fibroblasts to thyroid hormone in vitro.
Topics: Acetyltransferases; Animals; Cardiomegaly; Cells, Cultured; Collagen; DNA; Extracellular Matrix; Fib | 1992 |
Decreased collagen mRNA and regression of cardiac fibrosis in the ventricular myocardium of the tight skin mouse following thyroid hormone treatment.
Topics: Animals; Cardiomegaly; Collagen; Fibrosis; Heart Ventricles; Homeostasis; Male; Mice; Mice, Mutant S | 1992 |
The outcome of benign thyroid nodules correlates with the findings of fine needle biopsy.
Topics: Adult; Aged; Biopsy, Needle; Colloids; Female; Fibrosis; Humans; Hyperplasia; Lymphocytes; Male; Mid | 1991 |