Page last updated: 2024-11-06

thyroxine and Chronic Hepatitis C

thyroxine has been researched along with Chronic Hepatitis C in 17 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"Combined pegylated interferon and ribavirin therapy for chronic hepatitis C infection cause a wide range of side effects, including flu-like syndrome, hematological abnormalities, cardiovascular symptoms, gastrointestinal symptoms, pulmonary dysfunction, depression, and retinopathy."7.76[Occurrence of diabetic ketoacidosis and autoimmune thyroiditis in a patient treated with pegylated interferon-alpha 2b and ribavirin for chronic hepatitis C]. ( Jang, JY; Jeon, SR; Jeong, SW; Kim, BS; Kim, SK; Kim, YS; Lee, YN; Lim, JH; Roh, MO; Ryu, YS, 2010)
"Interferon (IFN) plus ribavirin therapy for chronic hepatitis C (CHC) virus infection has been associated with thyroid dysfunction."7.73Thyroid dysfunction in patients with chronic hepatitis C receiving a combined therapy of interferon and ribavirin: incidence, associated factors and prognosis. ( Changchien, CS; Kee, KM; Lee, CM; Lu, SN; Tung, HD; Wang, JH; Wang, PW, 2006)
"Subclinical hypothyroidism is common in children with CHC receiving treatment with pegylated IFN-α-2b and RBV, but in most cases is transient."5.48Transient Hypothyroidism and Autoimmune Thyroiditis in Children With Chronic Hepatitis C Treated With Pegylated-interferon-α-2b and Ribavirin. ( Azzari, C; Cananzi, M; D'Antiga, L; Indolfi, G; Nebbia, G; Resti, M; Ricci, S; Serranti, D; Stagi, S, 2018)
"Combined pegylated interferon and ribavirin therapy for chronic hepatitis C infection cause a wide range of side effects, including flu-like syndrome, hematological abnormalities, cardiovascular symptoms, gastrointestinal symptoms, pulmonary dysfunction, depression, and retinopathy."3.76[Occurrence of diabetic ketoacidosis and autoimmune thyroiditis in a patient treated with pegylated interferon-alpha 2b and ribavirin for chronic hepatitis C]. ( Jang, JY; Jeon, SR; Jeong, SW; Kim, BS; Kim, SK; Kim, YS; Lee, YN; Lim, JH; Roh, MO; Ryu, YS, 2010)
"Interferon (IFN) plus ribavirin therapy for chronic hepatitis C (CHC) virus infection has been associated with thyroid dysfunction."3.73Thyroid dysfunction in patients with chronic hepatitis C receiving a combined therapy of interferon and ribavirin: incidence, associated factors and prognosis. ( Changchien, CS; Kee, KM; Lee, CM; Lu, SN; Tung, HD; Wang, JH; Wang, PW, 2006)
"Despite aggressive treatment of hepatic encephalopathy, there was no clinical improvement."2.41Primary hypothyroidism masquerading as hepatic encephalopathy: case report and review of the literature. ( Jones, MP; Pilger, P; Thobe, N, 2000)
"Subclinical hypothyroidism is common in children with CHC receiving treatment with pegylated IFN-α-2b and RBV, but in most cases is transient."1.48Transient Hypothyroidism and Autoimmune Thyroiditis in Children With Chronic Hepatitis C Treated With Pegylated-interferon-α-2b and Ribavirin. ( Azzari, C; Cananzi, M; D'Antiga, L; Indolfi, G; Nebbia, G; Resti, M; Ricci, S; Serranti, D; Stagi, S, 2018)
"An association between Graves' disease (GD) and chronic hepatitis C (C-HC) has been observed both in the presence and the absence of recombinant interferon-alpha (rIFN-alpha) treatment."1.33Graves' disease in interferon-alpha-treated and untreated patients with chronic hepatitis C virus infection. ( Barilli, AL; Bertoni, R; Coiro, V; Delsignore, R; Di Seclì, C; Ferrari, C; Finardi, L; Jotti, GS; La Gioia, D; Minelli, R; Valli, MA, 2005)
"116 patients with chronic hepatitis B or C were consecutively investigated."1.31Thyroid hypoechogenicity in patients with chronic hepatitis receiving interferon-alpha therapy: evaluation by standardized grey scale ultrasonography. ( Bogner, J; Gross, M; Schiemann, U; Schmidt, F; Walli, R, 2002)
"Each case of hyperthyroidism has to be precisely evaluated."1.30[Hepatitis C virus infection and thyroid diseases]. ( Bailly, F; Broussolle, C; Steineur, MP; Trépo, C; Zoulim, F, 1999)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (17.65)18.2507
2000's9 (52.94)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Serranti, D1
Indolfi, G2
Nebbia, G1
Cananzi, M1
D'Antiga, L1
Ricci, S1
Stagi, S2
Azzari, C2
Resti, M2
Montes, ML1
Fraile, JM1
González, JJ1
Arribas, JR1
Moustafa, AH1
Ali, EM1
Mohamed, TM1
Abdou, HI1
Lee, YN1
Jeong, SW1
Lim, JH1
Ryu, YS1
Jeon, SR1
Kim, SK1
Jang, JY1
Kim, YS1
Kim, BS1
Roh, MO1
López, MM1
Arráez Monllor, M1
López Fernández, M1
Hervas Abad, E1
Hernández Alonso, E1
Tran, HA1
Ianna, EA1
Jones, TL1
Reeves, GE1
Zantut-Wittmann, DE1
Pavan, MH1
Pavin, EJ1
Goncales, FL1
Schiemann, U1
Walli, R1
Schmidt, F1
Bogner, J1
Gross, M1
Minelli, R3
Valli, MA3
Di Seclì, C2
Finardi, L2
Chiodera, P1
Bertoni, R2
Ferrari, C2
Barilli, AL2
Coiro, V2
Saccani Jotti, G1
Delsignore, R2
La Gioia, D1
Jotti, GS1
Kee, KM1
Lee, CM1
Wang, JH1
Tung, HD1
Changchien, CS1
Lu, SN1
Wang, PW1
Bartolini, E1
Salti, R1
de Martino, M1
Kanda, K1
Kayahara, T1
Seno, H1
Yamashita, Y1
Chiba, T1
Tsuboi, K1
Katayama, M1
Yuasa, R1
Matoba, H1
Nagayama, T1
Ihara, F1
Ooya, T1
Matsuo, K1
Otsuka, S1
Miyachi, Y1
Braverman, LE1
Schianchi, C1
Pedrazzoni, M1
Fiaccadori, F1
Salvi, M1
Magotti, MG1
Roti, E1
Broussolle, C1
Steineur, MP1
Bailly, F1
Zoulim, F1
Trépo, C1
Thobe, N1
Pilger, P1
Jones, MP1

Reviews

1 review available for thyroxine and Chronic Hepatitis C

ArticleYear
Primary hypothyroidism masquerading as hepatic encephalopathy: case report and review of the literature.
    Postgraduate medical journal, 2000, Volume: 76, Issue:897

    Topics: Aged; Diagnosis, Differential; Female; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Hypothy

2000

Trials

3 trials available for thyroxine and Chronic Hepatitis C

ArticleYear
Is steroid therapy needed in the treatment of destructive thyrotoxicosis induced by alpha-interferon in chronic hepatitis C?
    Hormone research, 2005, Volume: 63, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antiviral Agents; Female; Hepatitis C, Chronic; Humans; Hypothyroid

2005
Interferon-alpha-induced thyroid dysfunction in patients with chronic active hepatitis C: a transient, reversible and self-limited dysfunction.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:1

    Topics: Adult; Aged; Autoimmune Diseases; Female; Goiter; Hepatitis C, Chronic; Humans; Hypothyroidism; Inte

1998
Recombinant interferon alpha (rIFN-alpha) does not potentiate the effect of iodine excess on the development of thyroid abnormalities in patients with HCV chronic active hepatitis.
    Clinical endocrinology, 1999, Volume: 50, Issue:1

    Topics: Adult; Antibodies; Antiviral Agents; Female; Hepatitis C, Chronic; Humans; Interferon Type I; Iodide

1999

Other Studies

13 other studies available for thyroxine and Chronic Hepatitis C

ArticleYear
Transient Hypothyroidism and Autoimmune Thyroiditis in Children With Chronic Hepatitis C Treated With Pegylated-interferon-α-2b and Ribavirin.
    The Pediatric infectious disease journal, 2018, Volume: 37, Issue:4

    Topics: Adolescent; Antiviral Agents; Autoantibodies; Case-Control Studies; Child; Child, Preschool; Female;

2018
[Chorea during treatment with pegylated interferon and ribavirin in HIV-HCV coinfected patient].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:1

    Topics: Adult; Anti-HIV Agents; Antidepressive Agents; Antiviral Agents; Anxiety Disorders; Chorea; Citalopr

2009
Oxidative stress and thyroid hormones in patients with liver diseases.
    European journal of internal medicine, 2009, Volume: 20, Issue:7

    Topics: Adult; Alanine Transaminase; Antioxidants; Apolipoprotein A-I; Aspartate Aminotransferases; Biomarke

2009
[Occurrence of diabetic ketoacidosis and autoimmune thyroiditis in a patient treated with pegylated interferon-alpha 2b and ribavirin for chronic hepatitis C].
    The Korean journal of hepatology, 2010, Volume: 16, Issue:2

    Topics: Adult; Antiviral Agents; Diabetic Ketoacidosis; Drug Therapy, Combination; Female; Hepatitis C, Chro

2010
[Acute hallucinatory psychosis secondary to oral glucocorticoid treatment in a patient diagnosed with Sheehan's syndrome].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2011, Volume: 58, Issue:8

    Topics: Acute Disease; Female; Hallucinations; Hepatitis C, Chronic; Hormone Replacement Therapy; Humans; Hy

2011
The adjuvant role of thyroxine in the treatment of chronic hepatitis C infection.
    QJM : monthly journal of the Association of Physicians, 2012, Volume: 105, Issue:7

    Topics: Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha;

2012
Central hypothyroidism in patients with chronic hepatitis C and relation with interferon-alpha treatment.
    Endocrine regulations, 2011, Volume: 45, Issue:3

    Topics: Adult; Chi-Square Distribution; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Hypothyroidism; I

2011
Thyroid hypoechogenicity in patients with chronic hepatitis receiving interferon-alpha therapy: evaluation by standardized grey scale ultrasonography.
    European journal of medical research, 2002, Jun-28, Volume: 7, Issue:6

    Topics: Adult; Antiviral Agents; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Hypothyroidism;

2002
Graves' disease in interferon-alpha-treated and untreated patients with chronic hepatitis C virus infection.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2005, Volume: 53, Issue:1

    Topics: Antiviral Agents; Autoantibodies; Female; Graves Disease; Hepacivirus; Hepatitis C, Chronic; Humans;

2005
Thyroid dysfunction in patients with chronic hepatitis C receiving a combined therapy of interferon and ribavirin: incidence, associated factors and prognosis.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 2

    Topics: Antiviral Agents; Autoantibodies; Case-Control Studies; Female; Hepatitis C, Chronic; Humans; Interf

2006
Thyroid function and anti-thyroid autoantibodies in untreated children with vertically acquired chronic hepatitis C virus infection.
    Clinical endocrinology, 2008, Volume: 68, Issue:1

    Topics: Adolescent; Autoantibodies; Autoimmunity; Case-Control Studies; Child; Child, Preschool; Female; Hep

2008
Conversion from latent to symptomatic Sheehan's syndrome by pegylated interferon therapy for chronic hepatitis C.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:10

    Topics: Adrenocorticotropic Hormone; Antiviral Agents; Female; Hepatitis C, Chronic; Hormones; Humans; Hypop

2008
[Hepatitis C virus infection and thyroid diseases].
    La Revue de medecine interne, 1999, Volume: 20, Issue:9

    Topics: Adult; Antiviral Agents; Autoantibodies; Cross-Sectional Studies; Female; Hepatitis C; Hepatitis C,

1999