thyroxine has been researched along with Choriocarcinoma in 14 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 7.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "We have studied the uptake of 125I-thyroxine (125I-T4) in the human choriocarcinoma cell line JAR." | 7.69 | Uptake of thyroxine in the human choriocarcinoma cell line JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Payne, EJ, 1995) |
| "We compared the specificities of transport mechanisms for uptake and efflux of thyroid hormones in cells of the human choriocarcinoma cell line, JAR, to determine whether triiodothyronine (T3), thyroxine (T4) and reverse T3 (rT3) are carried by the same transport mechanism." | 3.70 | Comparison of mechanisms mediating uptake and efflux of thyroid hormones in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Rowan, KA, 1999) |
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 3.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "We have studied the uptake of 125I-thyroxine (125I-T4) in the human choriocarcinoma cell line JAR." | 3.69 | Uptake of thyroxine in the human choriocarcinoma cell line JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Payne, EJ, 1995) |
| "None of the patients with molar pregnancy was clinically thyrotoxic, though serum thyroxine (T4) was increased in 13 and free T4 concentrations were above normal in four of ten in whom measurements were made." | 1.26 | Thyroid function in molar pregnancy. ( Irie, M; Mizuno, M; Nagataki, S; Sakamoto, S; Shizume, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, K | 1 |
| Mostafa, MH | 1 |
| Mann, K | 1 |
| Schindler, AE | 1 |
| Hoermann, R | 1 |
| Tamaya, T | 1 |
| Trainer, TD | 1 |
| Howard, PL | 1 |
| Mitchell, AM | 4 |
| Manley, SW | 4 |
| Payne, EJ | 1 |
| Mortimer, RH | 5 |
| Prasad, PD | 1 |
| Leibach, FH | 1 |
| Mahesh, VB | 1 |
| Ganapathy, V | 1 |
| Rowan, KA | 2 |
| Powell, KA | 1 |
| Marx, M | 1 |
| Beck, JD | 1 |
| Grabenbauer, GG | 1 |
| Fahlbusch, R | 1 |
| Dörr, HG | 1 |
| Nagataki, S | 1 |
| Mizuno, M | 1 |
| Sakamoto, S | 1 |
| Irie, M | 1 |
| Shizume, K | 1 |
| Stahl, TJ | 1 |
| Romshe, CA | 1 |
| Sotos, JF | 1 |
| Giralt, SA | 1 |
| Dexeus, F | 1 |
| Amato, R | 1 |
| Sella, A | 1 |
| Logothetis, C | 1 |
| Cohen, JD | 1 |
| Utiger, RD | 1 |
2 reviews available for thyroxine and Choriocarcinoma
| Article | Year |
|---|---|
[Endocrine functional ovarian tumor].
Topics: Androgens; Choriocarcinoma; Chorionic Gonadotropin; Estrogens; Female; Granulosa Cell Tumor; Humans; | 2006 |
Thyroid function tests in thyroid and nonthyroid disease.
Topics: Adult; Aged; Autoantibodies; Calcitonin; Choriocarcinoma; Female; Fetus; Hepatitis; Humans; Hyperthy | 1983 |
12 other studies available for thyroxine and Choriocarcinoma
| Article | Year |
|---|---|
The human chorionic gonadotropin molecule from patients with trophoblastic diseases has a high thyrotropic activity but is less active in the ovary.
Topics: Adolescent; Adult; Animals; CHO Cells; Choriocarcinoma; Chorionic Gonadotropin; Cricetinae; Cyclic A | 2004 |
Uptake of thyroxine in the human choriocarcinoma cell line JAR.
Topics: Choriocarcinoma; Female; Humans; Kinetics; Ouabain; Temperature; Thyroxine; Time Factors; Triiodothy | 1995 |
Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.
Topics: Amino Acids; Biological Transport; Cell Line; Choline; Choriocarcinoma; Female; Humans; Hydrogen-Ion | 1994 |
Uptake of reverse T3 in the human choriocarcinoma cell line, JAr.
Topics: Choriocarcinoma; Female; Humans; Iodine Radioisotopes; Kinetics; Pregnancy; Thyroxine; Triiodothyron | 1999 |
Comparison of mechanisms mediating uptake and efflux of thyroid hormones in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Biological Transport, Active; Choriocarcinoma; Female; H | 1999 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenas | 2000 |
Gonadotrophin-independent puberty in a boy with a beta-HCG-secreting brain tumour.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Chorio | 2000 |
Thyroid function in molar pregnancy.
Topics: Adult; Body Weight; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Hype | 1977 |
Radioimmunoassay and the hormones of thyroid function.
Topics: Acromegaly; Adenoma, Chromophobe; Blood; Calcitonin; Choriocarcinoma; Female; Glucocorticoids; Goite | 1975 |
Intracranial human chorionic gonadotropin-secreting tumor with precocious puberty.
Topics: 17-Ketosteroids; Cerebral Ventricle Neoplasms; Child; Choriocarcinoma; Chorionic Gonadotropin; Femal | 1975 |
Hyperthyroidism in men with germ cell tumors and high levels of beta-human chorionic gonadotropin.
Topics: Adolescent; Adult; Choriocarcinoma; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Hu | 1992 |
Metastatic choriocarcinoma associated with hyperthyroidism.
Topics: Adolescent; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Hormones, Ectopic; Humans | 1970 |