Page last updated: 2024-11-06

thyroxine and Child Mental Disorders

thyroxine has been researched along with Child Mental Disorders in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
" Currently, there is no evidence that levothyroxine treatment, when initiated 8- to 20-week gestation (mostly between 12 and 17 weeks), for mild maternal thyroid hormone insufficiency during pregnancy reduces intellectual disability in offspring."4.98Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopmental disorders in offspring: A systematic review and meta-analysis. ( Baragwanath, G; Matthews, J; Russell, G; Thompson, W; Thompson-Coon, J; Vaidya, B, 2018)
"Primary congenital hypothyroidism is a disease associated with low serum thyroxine and elevated thyroid-stimulating hormone (TSH) levels."4.02Postnatal Serum Total Thyroxine of Very Preterm Infants and Long-Term Neurodevelopmental Outcome. ( Chen, YJ; Chou, YY; Chu, WY; Huang, CH; Iwata, O; Lin, CH; Lin, YC; Pan, YW; Wang, CY; Yu, WH, 2021)
" All women had a blood sample drawn in early pregnancy (median week 9), and the stored sample was used for measurement of free thyroxine and thyrotropin."3.88Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study. ( Andersen, S; Andersen, SL; Olsen, J; Vestergaard, P, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Lin, YC1
Wang, CY1
Pan, YW1
Chen, YJ1
Yu, WH1
Chou, YY1
Huang, CH1
Chu, WY1
Lin, CH1
Iwata, O1
Thompson, W1
Russell, G1
Baragwanath, G1
Matthews, J1
Vaidya, B1
Thompson-Coon, J1
Nelson, SM1
Haig, C1
McConnachie, A1
Sattar, N1
Ring, SM1
Smith, GD1
Lawlor, DA1
Lindsay, RS1
Andersen, SL1
Andersen, S1
Vestergaard, P1
Olsen, J1
Chen, Y1
Xue, F1
Min, H1
Dong, J1
Wang, Y2
Teng, W1
Xi, Q1
Chen, J1
Minatoya, M1
Naka Jima, S1
Sasaki, S1
Araki, A1
Miyashita, C1
Ikeno, T1
Nakajima, T1
Goto, Y1
Kishi, R1
Hirashima, R1
Michimae, H1
Takemoto, H1
Sasaki, A1
Kobayashi, Y1
Itoh, T1
Tukey, RH1
Fujiwara, R1

Reviews

3 reviews available for thyroxine and Child Mental Disorders

ArticleYear
Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopmental disorders in offspring: A systematic review and meta-analysis.
    Clinical endocrinology, 2018, Volume: 88, Issue:4

    Topics: Female; Humans; Hypothyroidism; Neurodevelopmental Disorders; Pregnancy; Pregnancy Complications; Pr

2018
The impact of gestational hypothyroxinemia on the cognitive and motor development of offspring.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2020, Volume: 33, Issue:11

    Topics: Animals; Biomarkers; Brain; Child Development; Cognition; Female; Fetal Development; Humans; Hypothy

2020
Maternal Hypothyroxinemia-Induced Neurodevelopmental Impairments in the Progeny.
    Molecular neurobiology, 2016, Volume: 53, Issue:3

    Topics: Brain; Cohort Studies; Endocrine Disruptors; Female; Forecasting; Humans; Infant, Newborn; Infant, P

2016

Other Studies

5 other studies available for thyroxine and Child Mental Disorders

ArticleYear
Postnatal Serum Total Thyroxine of Very Preterm Infants and Long-Term Neurodevelopmental Outcome.
    Nutrients, 2021, Mar-24, Volume: 13, Issue:4

    Topics: Congenital Hypothyroidism; Female; Humans; Infant, Newborn; Infant, Premature; Male; Neurodevelopmen

2021
Maternal thyroid function and child educational attainment: prospective cohort study.
    BMJ (Clinical research ed.), 2018, 02-20, Volume: 360

    Topics: Adolescent; Child; Child, Preschool; Educational Status; Female; Humans; Intelligence; Iodide Peroxi

2018
Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:4

    Topics: Adult; Child; Child, Preschool; Denmark; Female; Fetal Development; Humans; Infant; Male; Neurodevel

2018
Effects of prenatal phthalate exposure on thyroid hormone levels, mental and psychomotor development of infants: The Hokkaido Study on Environment and Children's Health.
    The Science of the total environment, 2016, Sep-15, Volume: 565

    Topics: Child Health; Diethylhexyl Phthalate; Environmental Pollutants; Female; Humans; Infant; Infant, Newb

2016
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
    Molecular pharmacology, 2016, Volume: 90, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expre

2016