thyroxine has been researched along with Cerebral Palsy in 8 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationship of thyroxine supplementation for transient hypothyroxinemia of prematurity to the incidence of cerebral palsy (CP) in infants <28 weeks of gestation is unclear." | 7.77 | Thyroxine for transient hypothyroxinemia and cerebral palsy in extremely preterm infants. ( Arisaka, O; Kuribayashi, R; Nitta, A; Suzumura, H; Tsuboi, Y; Watabe, Y, 2011) |
| "The relationship of thyroxine supplementation for transient hypothyroxinemia of prematurity to the incidence of cerebral palsy (CP) in infants <28 weeks of gestation is unclear." | 3.77 | Thyroxine for transient hypothyroxinemia and cerebral palsy in extremely preterm infants. ( Arisaka, O; Kuribayashi, R; Nitta, A; Suzumura, H; Tsuboi, Y; Watabe, Y, 2011) |
| "In analyses adjusted for gestational age, infants with severe hypothyroxinemia had a risk of disabling cerebral palsy that was nearly 11 times that of infants without hypothyroxinemia (odds ratio, 10." | 3.69 | The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age. ( Lorenz, JM; Paneth, N; Pinto-Martin, JA; Reuss, ML; Susser, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzumura, H | 1 |
| Nitta, A | 1 |
| Tsuboi, Y | 1 |
| Watabe, Y | 1 |
| Kuribayashi, R | 1 |
| Arisaka, O | 1 |
| La Gamma, EF | 1 |
| Paneth, N | 2 |
| Morreale de Escobar, G | 1 |
| Vasil'eva, EM | 1 |
| Shor, TA | 1 |
| Poddubnaia, AE | 1 |
| Reuss, ML | 1 |
| Pinto-Martin, JA | 1 |
| Lorenz, JM | 1 |
| Susser, M | 1 |
| Vulsma, T | 1 |
| Kok, JH | 1 |
| Arii, J | 1 |
| Tanabe, Y | 1 |
| Makino, M | 1 |
| Sato, H | 1 |
| Kohno, Y | 1 |
| Nelson, KB | 1 |
| Ellenberg, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transient Hypothyroxinemia of Prematurity: Electrophysiological Changes in the Preterm Infants' Brain, a Retrospective Study[NCT03493113] | 87 participants (Actual) | Observational | 2011-10-31 | Completed | |||
| The Effect of Perinatal Stress on the Development of Preterm Infants[NCT02623400] | 200 participants (Anticipated) | Observational | 2016-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thyroxine and Cerebral Palsy
| Article | Year |
|---|---|
Clinical importance of hypothyroxinemia in the preterm infant and a discussion of treatment concerns.
Topics: Cerebral Palsy; Cognition Disorders; Developmental Disabilities; Hormone Replacement Therapy; Humans | 2012 |
Maternal hypothyroxinemia versus hypothyroidism and potential neurodevelopmental. Alterations of her offspring.
Topics: Brain; Cerebral Palsy; Congenital Hypothyroidism; Embryonic and Fetal Development; Female; Gestation | 2003 |
6 other studies available for thyroxine and Cerebral Palsy
| Article | Year |
|---|---|
Thyroxine for transient hypothyroxinemia and cerebral palsy in extremely preterm infants.
Topics: Cerebral Palsy; Child, Preschool; Congenital Hypothyroidism; Drug Administration Schedule; Follow-Up | 2011 |
[Changes of the thyroid hormone status in children with cerebral palsy and other neurological pathology].
Topics: Age Factors; Birth Injuries; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Cystitis; Fema | 2005 |
The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age.
Topics: Cerebral Palsy; Child Development; Child, Preschool; Cohort Studies; Humans; Infant, Newborn; Infant | 1996 |
The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age.
Topics: Cerebral Palsy; Child Development; Child, Preschool; Cohort Studies; Humans; Infant, Newborn; Infant | 1996 |
The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age.
Topics: Cerebral Palsy; Child Development; Child, Preschool; Cohort Studies; Humans; Infant, Newborn; Infant | 1996 |
The relation of transient hypothyroxinemia in preterm infants to neurologic development at two years of age.
Topics: Cerebral Palsy; Child Development; Child, Preschool; Cohort Studies; Humans; Infant, Newborn; Infant | 1996 |
Prematurity-associated neurologic and developmental abnormalities and neonatal thyroid function.
Topics: Cerebral Palsy; Humans; Infant, Newborn; Infant, Premature; Intellectual Disability; Thyroxine | 1996 |
Children with irreversible brain damage associated with hypothyroidism and multiple intracranial calcifications.
Topics: Basal Ganglia Diseases; Calcinosis; Cerebral Palsy; Child, Preschool; Female; Growth Disorders; Huma | 2002 |
Antecedents of cerebral palsy. I. Univariate analysis of risks.
Topics: Anti-Bacterial Agents; Birth Weight; Cerebral Palsy; Delivery, Obstetric; Estrogens; Female; Humans; | 1985 |