thyroxine has been researched along with Celiac Disease in 30 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Celiac Disease: A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The preferred treatment for hypothyroidism is oral levothyroxine (LT4) ingestion, in doses that ensure a sustained state of hormonal balance." | 8.88 | The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption. ( Ruchała, M; Szczepanek-Parulska, E; Zybek, A, 2012) |
| "Celiac disease was confirmed by elevated serum antigliadin antibody." | 5.33 | [Autoimmune hypothyroidism nonresponsive to high doses of levothyroxine and severe hypocalcemia]. ( Silva, CM; Souza, MV, 2005) |
| "The preferred treatment for hypothyroidism is oral levothyroxine (LT4) ingestion, in doses that ensure a sustained state of hormonal balance." | 4.88 | The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption. ( Ruchała, M; Szczepanek-Parulska, E; Zybek, A, 2012) |
| " The presence of primary autoimmune hypothyroidism makes this case specific, since the inability for optimal substitution therapy with a high daily dose of levothyroxine provoked the suspicion of celiac disease." | 3.81 | Osteoporosis reversibility in a patient with celiac disease and primary autoimmune hypothyroidism on gluten free diet--a case report. ( Bajkin, I; Ičin, T; Kovačev-Zavišić, B; Medić-Stojanoska, M; Novaković-Paro, J, 2015) |
| "Levothyroxine malabsorption likely occurs with hypothyroidism and untreated celiac disease." | 3.78 | Celiac disease and hypothyroidism. ( Collins, D; Nathan, M; Wilcox, R; Zubarik, R, 2012) |
| "A 61-year-old white woman with primary hypothyroidism, systemic lupus erythematosus, celiac disease, and history of Whipple resection for pancreatic cancer was euthyroid with levothyroxine 175-188 micrograms/d." | 3.71 | Exaggerated levothyroxine malabsorption due to calcium carbonate supplementation in gastrointestinal disorders. ( Csako, G; McGriff, NJ; Pucino, F; Rotman-Pikielny, P; Sarlis, NJ, 2001) |
| "Osteoporosis is a skeletal disorder characterized by decreased mass and compromised bone strength predisposing to an increased risk of fractures." | 2.52 | Management of endocrine disease: Secondary osteoporosis: pathophysiology and management. ( Canalis, E; Mirza, F, 2015) |
| "Celiac disease was confirmed by elevated serum antigliadin antibody." | 1.33 | [Autoimmune hypothyroidism nonresponsive to high doses of levothyroxine and severe hypocalcemia]. ( Silva, CM; Souza, MV, 2005) |
| " Patients with chronic thyroiditis treated with a high replacement dosage of levothyroxin (125-200 microg daily) had higher serum levels of IgA antigliadin antibodies in comparison with patients treated with a lower dosage (50-100 microg daily) (medians: 13." | 1.32 | IgA and IgG antigliadin, IgA anti-tissue transglutaminase and antiendomysial antibodies in patients with autoimmune thyroid diseases and their relationship to thyroidal replacement therapy. ( Jiskra, J; Kocna, P; Límanová, Z; Vanícková, Z, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.00) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 11 (36.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creo, AL | 1 |
| Candela, N | 1 |
| Lee, MM | 1 |
| Feldman, PM | 1 |
| Joshi, AS | 1 |
| Varthakavi, PK | 1 |
| Bhagwat, NM | 1 |
| Thiruvengadam, NR | 1 |
| Mirza, F | 1 |
| Canalis, E | 1 |
| Kovačev-Zavišić, B | 1 |
| Ičin, T | 1 |
| Novaković-Paro, J | 1 |
| Medić-Stojanoska, M | 1 |
| Bajkin, I | 1 |
| Zubarik, R | 2 |
| Ganguly, E | 1 |
| Nathan, M | 2 |
| Vecchio, J | 1 |
| Liwanpo, L | 1 |
| Hershman, JM | 1 |
| Latif, S | 1 |
| Jamal, A | 1 |
| Memon, I | 1 |
| Yasmeen, S | 1 |
| Tresa, V | 1 |
| Shaikh, S | 1 |
| Diamanti, A | 1 |
| Ferretti, F | 1 |
| Guglielmi, R | 1 |
| Panetta, F | 1 |
| Colistro, F | 1 |
| Cappa, M | 1 |
| Daniele, A | 1 |
| Sole Basso, M | 1 |
| Noto, C | 1 |
| Crisogianni, M | 1 |
| Castro, M | 1 |
| Ramadhan, A | 1 |
| Tamilia, M | 1 |
| Virili, C | 1 |
| Bassotti, G | 1 |
| Santaguida, MG | 1 |
| Iuorio, R | 1 |
| Del Duca, SC | 1 |
| Mercuri, V | 1 |
| Picarelli, A | 1 |
| Gargiulo, P | 1 |
| Gargano, L | 1 |
| Centanni, M | 1 |
| Collins, D | 1 |
| Wilcox, R | 1 |
| Ruchała, M | 1 |
| Szczepanek-Parulska, E | 1 |
| Zybek, A | 1 |
| Arvola, T | 1 |
| Mustalahti, K | 1 |
| Saha, MT | 1 |
| Vehmanen, P | 1 |
| Partanen, J | 1 |
| Ashorn, M | 1 |
| d'Estève-Bonetti, L | 1 |
| Bennet, AP | 1 |
| Malet, D | 1 |
| Hoff, M | 1 |
| Louvet, JP | 1 |
| Caron, P | 1 |
| Jiskra, J | 1 |
| Límanová, Z | 1 |
| Vanícková, Z | 1 |
| Kocna, P | 1 |
| Acquaviva, A | 1 |
| Municchi, G | 1 |
| Marconcini, S | 1 |
| D'Ambrosio, A | 1 |
| Morgese, G | 1 |
| HISS, JM | 1 |
| DOWLING, JT | 1 |
| McDermott, JH | 1 |
| Coss, A | 1 |
| Walsh, CH | 1 |
| Silva, CM | 1 |
| Souza, MV | 1 |
| Caputo, M | 1 |
| Brizzolara, R | 1 |
| Schiavo, M | 1 |
| Salmaso, C | 1 |
| Pesce, G | 1 |
| Bagnasco, M | 1 |
| Hadithi, M | 1 |
| de Boer, H | 1 |
| Meijer, JW | 1 |
| Willekens, F | 1 |
| Kerckhaert, JA | 1 |
| Heijmans, R | 1 |
| Peña, AS | 1 |
| Stehouwer, CD | 1 |
| Mulder, CJ | 1 |
| Farthing, MJ | 1 |
| Rees, LH | 1 |
| Edwards, CR | 1 |
| Byfield, PG | 1 |
| Himsworth, RL | 1 |
| Dawson, AM | 1 |
| Franzese, A | 1 |
| Limauro, R | 1 |
| Ecuba, P | 1 |
| Campanile, F | 1 |
| De Martino, F | 1 |
| Tenore, A | 1 |
| Goswami, R | 1 |
| Tandon, RK | 1 |
| Dudha, A | 1 |
| Kochupillai, N | 1 |
| Bätge, B | 1 |
| Langsteger, W | 1 |
| Bos, I | 1 |
| Peters, A | 1 |
| Valentino, R | 2 |
| Savastano, S | 2 |
| Tommaselli, AP | 2 |
| Dorato, M | 2 |
| Scarpitta, MT | 2 |
| Gigante, M | 2 |
| Lombardi, G | 2 |
| Troncone, R | 2 |
| Micillo, M | 1 |
| Paparo, F | 1 |
| Petrone, E | 1 |
| Roldán, MB | 1 |
| Alonso, M | 1 |
| Barrio, R | 1 |
| Csako, G | 1 |
| McGriff, NJ | 1 |
| Rotman-Pikielny, P | 1 |
| Sarlis, NJ | 1 |
| Pucino, F | 1 |
| Husslein, H | 1 |
| Stöger, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Detection of Celiac Disease in Patients With Hypothyroidism[NCT01862510] | 500 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for thyroxine and Celiac Disease
| Article | Year |
|---|---|
Management of endocrine disease: Secondary osteoporosis: pathophysiology and management.
Topics: Acromegaly; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Autoimmune Diseases; Celiac Disea | 2015 |
Conditions and drugs interfering with thyroxine absorption.
Topics: Aluminum Hydroxide; Animals; Antacids; Biological Availability; Calcium Carbonate; Celiac Disease; C | 2009 |
The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption.
Topics: Celiac Disease; Diet, Gluten-Free; Dose-Response Relationship, Drug; Drug Resistance; Gastrointestin | 2012 |
[The clinical picture and therapy of Sheehan's syndrome (author's transl)].
Topics: Addison Disease; Amenorrhea; Anorexia Nervosa; Celiac Disease; Cortisone; Diagnosis, Differential; F | 1974 |
2 trials available for thyroxine and Celiac Disease
| Article | Year |
|---|---|
Celiac disease detection in hypothyroid patients requiring elevated thyroid supplementation: A prospective cohort study.
Topics: Aged; Celiac Disease; Cohort Studies; Dose-Response Relationship, Drug; Drug Dosage Calculations; Dr | 2015 |
Prevalence of coeliac disease in patients with thyroid autoimmunity.
Topics: Adolescent; Adult; Celiac Disease; Child; Diet; Female; Glutens; Humans; Male; Thyroiditis, Autoimmu | 1999 |
24 other studies available for thyroxine and Celiac Disease
| Article | Year |
|---|---|
An Unusual Manifestation of Celiac Disease in an Adolescent With Down Syndrome and Graves Disease.
Topics: Adolescent; Celiac Disease; Child; Contraceptives, Oral, Hormonal; Diet, Gluten-Free; Down Syndrome; | 2017 |
Graves' disease and coeliac disease: screening and treatment dilemmas.
Topics: Adult; Celiac Disease; Diet, Gluten-Free; Female; Graves Disease; Humans; Iodine Radioisotopes; Thyr | 2014 |
Osteoporosis reversibility in a patient with celiac disease and primary autoimmune hypothyroidism on gluten free diet--a case report.
Topics: Calcium; Celiac Disease; Cholecalciferol; Diet, Gluten-Free; Female; Humans; Hyperparathyroidism, Se | 2015 |
Multiple autoimmune syndrome: Hashimoto's thyroiditis, coeliac disease and systemic lupus erythematosus (SLE).
Topics: Celiac Disease; Child; Female; Hashimoto Disease; Humans; Hypothyroidism; Lupus Erythematosus, Syste | 2010 |
Thyroid autoimmunity in children with coeliac disease: a prospective survey.
Topics: Adolescent; Autoimmune Diseases; Celiac Disease; Child; Child, Preschool; Diet, Gluten-Free; Female; | 2011 |
Treatment-refractory hypothyroidism.
Topics: Addison Disease; Biological Availability; Celiac Disease; Humans; Hypothyroidism; Intestinal Absorpt | 2012 |
Atypical celiac disease as cause of increased need for thyroxine: a systematic study.
Topics: Adult; Celiac Disease; Cohort Studies; Diet, Gluten-Free; Female; Hashimoto Disease; Humans; Hypothy | 2012 |
Celiac disease and hypothyroidism.
Topics: Case-Control Studies; Celiac Disease; Chi-Square Distribution; Comorbidity; Female; Humans; Hypothyr | 2012 |
Celiac disease, thyrotoxicosis, and autoimmune hepatitis in a child.
Topics: Alanine Transaminase; Autoimmune Diseases; Celiac Disease; Child; Diet; Female; Gliadin; Glutens; Ha | 2002 |
Gluten-induced enteropathy (coeliac disease) revealed by resistance to treatment with levothyroxine and alfacalcidol in a sixty-eight-year-old patient: a case report.
Topics: Absorption; Aged; Celiac Disease; Drug Resistance; Female; Humans; Hydroxycholecalciferols; Hypothyr | 2002 |
IgA and IgG antigliadin, IgA anti-tissue transglutaminase and antiendomysial antibodies in patients with autoimmune thyroid diseases and their relationship to thyroidal replacement therapy.
Topics: Adolescent; Adult; Aged; Calcium; Celiac Disease; Dose-Response Relationship, Drug; Female; Gliadin; | 2003 |
Celiac disease in a patient with beta-thalassemia major.
Topics: beta-Thalassemia; Blood Transfusion; Celiac Disease; Follow-Up Studies; Glutens; Hepatitis C; Humans | 2003 |
Thyroxine metabolism in untreated and treated pancreatic steatorrhea.
Topics: Celiac Disease; Humans; Steatorrhea; Thyroxine | 1962 |
Celiac disease presenting as resistant hypothyroidism.
Topics: Autoimmune Diseases; Celiac Disease; Drug Resistance; Female; Humans; Hypothyroidism; Middle Aged; T | 2005 |
[Autoimmune hypothyroidism nonresponsive to high doses of levothyroxine and severe hypocalcemia].
Topics: Celiac Disease; Drug Resistance; Female; Hashimoto Disease; Humans; Hypocalcemia; Middle Aged; Sever | 2005 |
Occurrence of overt celiac disease in the elderly following total thyroidectomy.
Topics: Aged; Calcium; Celiac Disease; Dose-Response Relationship, Drug; Drug Resistance; Female; Hormone Re | 2006 |
Coeliac disease in Dutch patients with Hashimoto's thyroiditis and vice versa.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Celiac Disease; Female; Hashimoto Disease; HLA-D | 2007 |
Thyroid hormones and the regulation of thyroid function in men with coeliac disease.
Topics: Adolescent; Adult; Aged; Celiac Disease; Crohn Disease; Humans; Male; Middle Aged; Thyroid Gland; Th | 1982 |
[L-T4 malabsorption determined by intolerance to cow's milk proteins and celiac disease in a patient with congenital hypothyroidism. A clinical case].
Topics: Celiac Disease; Congenital Hypothyroidism; Humans; Hypothyroidism; Infant; Intestinal Absorption; Ma | 1993 |
Prevalence and significance of steatorrhea in patients with active Graves' disease.
Topics: Absorption; Adult; Antithyroid Agents; Body Mass Index; Carbimazole; Case-Control Studies; Celiac Di | 1998 |
[Pseudohyperthyroxinemia in endemic sprue--reversibility with a gluten-free diet].
Topics: Celiac Disease; Diagnosis, Differential; Diarrhea; Enzyme-Linked Immunosorbent Assay; Gastroscopy; G | 1998 |
Unusual association of thyroiditis, Addison's disease, ovarian failure and celiac disease in a young woman.
Topics: Addison Disease; Adult; Autoantibodies; Autoimmune Diseases; Celiac Disease; Cortisone; Estrogens, C | 1999 |
Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Autoantibodies; Celiac Disease; Child; Child, Preschool; Diabetes Mellitus, Type | 1999 |
Exaggerated levothyroxine malabsorption due to calcium carbonate supplementation in gastrointestinal disorders.
Topics: Antacids; Calcium Carbonate; Celiac Disease; Female; Humans; Hypothyroidism; Intestinal Absorption; | 2001 |