Page last updated: 2024-11-06

thyroxine and Carpal Tunnel Syndrome

thyroxine has been researched along with Carpal Tunnel Syndrome in 6 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Research Excerpts

ExcerptRelevanceReference
"Also, depression is assessed with special focus on the two key symptoms: depressed mood and anhedonia."1.40The HAPPY study (Holistic Approach to Pregnancy and the first Postpartum Year): design of a large prospective cohort study. ( Broeren, MA; Kuppens, SM; Meems, M; Nabbe, KC; Oei, SG; Pop, VJ; Truijens, SE; van Son, MJ; Wijnen, HA, 2014)
"This would suggest that the tarsal tunnel syndrome is frequently encountered in myxoedema in association with the carpal tunnel syndrome."1.27The tarsal tunnel syndrome in hypothyroidism. ( Mackworth-Young, CG; McKeran, RO; Schwartz, MS, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Truijens, SE1
Meems, M1
Kuppens, SM1
Broeren, MA1
Nabbe, KC1
Wijnen, HA1
Oei, SG1
van Son, MJ1
Pop, VJ1
Yerdelen, D1
Ertorer, E1
KoƧ, F1
Ghannoum, JE1
Odingo, NA1
Provost, N1
Geoghegan, JM1
Clark, DI1
Bainbridge, LC1
Smith, C1
Hubbard, R1
Monden, T1
Iwata, C1
Hashikabe, Y1
Kasai, K1
Schwartz, MS1
Mackworth-Young, CG1
McKeran, RO1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900]Phase 2164 participants (Anticipated)Interventional2022-05-25Recruiting
Basal Joint Arthroplasty and Carpal Tunnel Release Comparing Single Versus Double Incision. Randomized Clinical Trial[NCT04391751]40 participants (Actual)Interventional2018-01-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thyroxine and Carpal Tunnel Syndrome

ArticleYear
[Hypothyroid neuropathy].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Carpal Tunnel Syndrome; Diagnosis, Differential; Facial Paralysis; Humans; Hypothyroidism; Periphera

2006

Other Studies

5 other studies available for thyroxine and Carpal Tunnel Syndrome

ArticleYear
The HAPPY study (Holistic Approach to Pregnancy and the first Postpartum Year): design of a large prospective cohort study.
    BMC pregnancy and childbirth, 2014, Sep-08, Volume: 14

    Topics: Anhedonia; Autoantibodies; Breast Feeding; Carpal Tunnel Syndrome; Chorionic Gonadotropin; Delivery,

2014
The effects of hypothyroidism on strength-duration properties of peripheral nerve.
    Journal of the neurological sciences, 2010, Jul-15, Volume: 294, Issue:1-2

    Topics: Adult; Carpal Tunnel Syndrome; Case-Control Studies; Female; Hormone Replacement Therapy; Humans; Hy

2010
Clinico-pathologic conference: case 6.
    Head and neck pathology, 2009, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell;

2009
Risk factors in carpal tunnel syndrome.
    Journal of hand surgery (Edinburgh, Scotland), 2004, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car

2004
Risk factors in carpal tunnel syndrome.
    Journal of hand surgery (Edinburgh, Scotland), 2004, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car

2004
Risk factors in carpal tunnel syndrome.
    Journal of hand surgery (Edinburgh, Scotland), 2004, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car

2004
Risk factors in carpal tunnel syndrome.
    Journal of hand surgery (Edinburgh, Scotland), 2004, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car

2004
The tarsal tunnel syndrome in hypothyroidism.
    Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:5

    Topics: Aged; Carpal Tunnel Syndrome; Female; Humans; Hypothyroidism; Male; Median Nerve; Middle Aged; Neura

1983