thyroxine has been researched along with Cardiovascular Diseases in 187 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subclinical hypothyroidism is a biochemical condition defined by elevated serum thyroid-stimulating hormone levels in the setting of normal levels of the peripheral thyroid hormones, thyroxine and triiodothyronine." | 9.05 | Levothyroxine for the Treatment of Subclinical Hypothyroidism and Cardiovascular Disease. ( Leung, AM; Sue, LY, 2020) |
| "Treatment with levothyroxine did not significantly change the risk of cardiovascular outcomes in older adults with subclinical hypothyroidism, irrespective of a history of cardiovascular disease and age." | 8.02 | Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. ( Blum, MR; Collet, TH; Dekkers, OM; den Elzen, WPJ; Du Puy, RS; Gussekloo, J; Jukema, JW; Kearney, PM; Mooijaart, SP; O'Keeffe, L; Poortvliet, RKE; Quinn, TJ; Rodondi, N; Sattar, N; Stott, DJ; Trompet, S; Westendorp, RGJ; Zijlstra, LE, 2021) |
| "Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0." | 7.96 | The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020) |
| "Hypothyroidism has detrimental effects on the cardiovascular system, but controversy remains concerning the benefits of levothyroxine (L-T4) substitution in patients with heart failure (HF)." | 7.91 | Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study. ( Einfeldt, MN; Faber, J; Gislason, GH; Khalid, U; Kristensen, SL; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2019) |
| " In the present investigation, effects of periplogenin-3- O-D-glucopyranosyl (1→6)(1→4)-D-cymaropyranoside, isolated from the vegetable, LAGENARIA SICERARIA, in L-thyroxine (L-T₄)-induced hyperthyroidism and in related cardiovascular abnormalities have been revealed in Wistar albino rats." | 7.77 | Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems. ( Kar, A; Panda, S, 2011) |
| "Chronic iodine deficiency (ID) increases thyrotropin (TSH) concentrations and produces a thyroid hormone pattern consistent with subclinical hypothyroidism (ScH)." | 7.75 | Iodine treatment in children with subclinical hypothyroidism due to chronic iodine deficiency decreases thyrotropin and C-peptide concentrations and improves the lipid profile. ( Aeberli, I; Bridson, J; Chaouki, N; Grimci, L; Jooste, PL; Mbhenyane, X; Melse-Boonstra, A; Zimmermann, MB, 2009) |
| "Controversy surrounds the issue of whether levothyroxine treatment improves lipid profile in patients with subclinical hypothyroidism (SHT)." | 7.75 | [Effect of treatment with levothyroxine in the lipid profile of the patients with subclinical hypothyroidism]. ( Prats Julià, M, 2009) |
| "To investigate the clinical relevance of l-thyroxine (l-T(4)) substitution therapy in borderline hypothyroidism." | 7.74 | Cardiac effects of L-thyroxine administration in borderline hypothyroidism. ( Cambuli, VM; Deidda, M; Mariotti, S; Mercuro, G; Pigliaru, F; Putzu, C; Vargiu, S; Zoncu, S, 2008) |
| " After L: -thyroxine, CFR increased significantly in overt and subclinical hypothyroidism with respect to the baseline measurements (P < 0." | 7.74 | Coronary flow reserve after L-thyroxine therapy in Hashimoto's thyroiditis patients with subclinical and overt hypothyroidism. ( Bugra, Z; Cimen, AO; Elitok, A; Kasikcioglu, E; Kurt, R; Mercanoglu, F; Oflaz, H; Onur, I; Ozbey, N; Pamukcu, B; Sen, F; Turkmen, K, 2007) |
| "To evaluate cardiovascular functionality in patients with thyroid cancer, we have performed echocardiography and ambulatory blood pressure monitoring in 19 women with differentiated thyroid carcinoma during thyroxine withdrawal, at three time points: the last day on TSH-suppressive thyroxine doses (subclinical or mild hyperthyroidism), 4-7 days after withdrawal (normal free thyroxine (FT4) and free triiodothyronine (FT3) levels), and before 131I whole body scanning (overt hypothyroidism)." | 7.72 | Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma. ( Barrios, V; Botella-Carretero, JI; Caballero, C; Escobar-Morreale, HF; García-Robles, R; Gómez-Bueno, M; Sancho, J, 2004) |
| " The aim of the present study was to assess plasma total homocysteine (tHCys) concentrations in hypo- as well as hyperthyroid patients before and after treatment, and to evaluate the role of potential determinants of plasma tHCys levels in these patients." | 7.71 | Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism. ( Blom, HJ; Diekman, MJ; Tijssen, JG; van der Put, NM; Wiersinga, WM, 2001) |
| "We found a higher plasma concentration of total homocysteine (tHcy), an independent risk factor for cardiovascular disease, in patients with hypothyroidism (mean, 16." | 7.70 | Plasma total homocysteine levels in hyperthyroid and hypothyroid patients. ( Aakvaag, A; Aanderud, S; Ericsson, UB; Lien, EA; Nedrebø, BG; Nygård, O; Refsum, H; Ueland, PM, 1998) |
| "Hypothyroidism is associated with premature atherosclerosis and cardiovascular disease." | 6.71 | Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial. ( Christ-Crain, M; Guglielmetti, M; Huber, PR; Meier, C; Müller, B; Riesen, W; Staub, JJ, 2003) |
| "Inflammation is a major risk factor for cardiovascular complications." | 5.43 | Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. ( Abbas, AM; Sakr, HF, 2016) |
| "We conducted comprehensive searches on MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Database of Systematic Reviews, JBI Evidence Synthesis, the PROSPERO register, Epistemonikos Database and PDQ Evidence from inception to February and July 2021 using keywords on subclinical hypothyroidism, treatment with levothyroxine, monitoring and primary outcomes (all-cause mortality, cardiovascular events, stroke, frailty fractures and quality of life)." | 5.22 | The impact of the management strategies for patients with subclinical hypothyroidism on long-term clinical outcomes: An umbrella review. ( Agrawal, U; Azcoaga-Lorenzo, A; Bauer, BS; Fagbamigbe, AF; McCowan, C, 2022) |
| "There is a 3-fold increased risk of developing overt hypothyroidism with dietary supplementation of 16 mg soy phytoestrogens with subclinical hypothyroidism." | 5.15 | The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomized, double-blind, crossover study. ( Atkin, SL; Chapman, T; Kilpatrick, ES; Manuchehri, AM; Rigby, AS; Sathyapalan, T; Thatcher, NJ, 2011) |
| "Overt hypothyroidism may result in accelerated atherosclerosis and coronary heart disease (CHD) presumably because of the associated hypertension, hypercholesterolemia, and hyperhomocysteinemia." | 5.10 | Risk factors for cardiovascular disease in women with subclinical hypothyroidism. ( Aviv, A; Herer, P; Lavie, L; Luboshitzky, R, 2002) |
| "Subclinical hypothyroidism is a biochemical condition defined by elevated serum thyroid-stimulating hormone levels in the setting of normal levels of the peripheral thyroid hormones, thyroxine and triiodothyronine." | 5.05 | Levothyroxine for the Treatment of Subclinical Hypothyroidism and Cardiovascular Disease. ( Leung, AM; Sue, LY, 2020) |
| "Subclinical hypothyroidism (also known as compensated hypothyroidism or mild hypothyroidism) is a condition associated with a raised serum concentration of thyroid stimulating hormone (TSH) but a normal serum free thyroxine (FT4)." | 4.95 | Subclinical hypothyroidism: Should we treat? ( Redford, C; Vaidya, B, 2017) |
| "Subclinical hypothyroidism (SH) is characterized by a mildly elevated concentration of thyroid stimulating hormone (TSH) despite free thyroxine (FT4) and triiodothyronine (FT3) levels within the reference range." | 4.93 | Nitric Oxide as a Marker for Levo-Thyroxine Therapy in Subclinical Hypothyroid Patients. ( Bajic, V; Gluvic, Z; Isenovic, ER; Obradovic, M; Panic, A; Sudar-Milovanovic, E; Trebaljevac, J; Zarkovic, M, 2016) |
| "Subclinical hypothyroidism, which is defined as elevated thyroid-stimulating hormone (TSH) levels with free thyroxine concentrations within the reference range, is a common disorder that increases with age and affects up to 18% of the elderly, with a higher prevalence in women compared to men." | 4.90 | Subclinical hypothyroidism: summary of evidence in 2014. ( Baumgartner, C; Blum, MR; Rodondi, N, 2014) |
| "Controversy remains as to the risk of cardiovascular disease (CVD) associated with subclinical hypothyroidism (SCH), defined as an increased serum thyrotropin (TSH) concentration with normal free thyroxine and triiodothyronine levels." | 4.84 | Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence? ( Duntas, LH; Wartofsky, L, 2007) |
| "Treatment with levothyroxine did not significantly change the risk of cardiovascular outcomes in older adults with subclinical hypothyroidism, irrespective of a history of cardiovascular disease and age." | 4.02 | Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. ( Blum, MR; Collet, TH; Dekkers, OM; den Elzen, WPJ; Du Puy, RS; Gussekloo, J; Jukema, JW; Kearney, PM; Mooijaart, SP; O'Keeffe, L; Poortvliet, RKE; Quinn, TJ; Rodondi, N; Sattar, N; Stott, DJ; Trompet, S; Westendorp, RGJ; Zijlstra, LE, 2021) |
| "Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0." | 3.96 | The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020) |
| " Amiodarone induced hypothyroidism is treated with levothyroxine and amiodarone taking is not interrupted." | 3.96 | Pharmacologically induced thyreopathy in patients with cardiovascular disease. ( Brutvan, T; Ježková, J; Krátký, J, 2020) |
| "Hypothyroidism has detrimental effects on the cardiovascular system, but controversy remains concerning the benefits of levothyroxine (L-T4) substitution in patients with heart failure (HF)." | 3.91 | Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study. ( Einfeldt, MN; Faber, J; Gislason, GH; Khalid, U; Kristensen, SL; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2019) |
| " To further evaluate the effect of thyroxine replacement therapy (TRT) on mortality, we divided patients with hypothyroidism into two groups: patients who received TRT and those who did not." | 3.88 | Association of Hypothyroidism With All-Cause Mortality: A Cohort Study in an Older Adult Population. ( Huang, HK; Kao, SL; Wang, JH, 2018) |
| "CV = cardiovascular DMN = diabetic nephropathy eGFR = estimated glomerular filtration rate fT4 = free thyroxine HbA1c = glycosylated hemoglobin HR = hazard ratio hs-CRP = high-sensitivity C-reactive protein LDL-C = low-density lipoprotein cholesterol SCH = subclinical hypothyroidism T2DM = type 2 diabetes THRT = thyroid hormone replacement therapy TSH = thyroid-stimulating hormone." | 3.88 | THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM. ( Cha, MU; Han, SH; Jhee, JH; Kang, SW; Kee, YK; Kim, H; Kim, S; Lee, M; Park, JT; Park, S; Seo, C; Yoo, TH; Yun, HR, 2018) |
| "Subclinical hypothyroidism (SH) is defined as an elevated serum thyroid-stimulating hormone (TSH) level with free thyroxine (fT4) level in the normal range." | 3.85 | Association of Subclinical Hypothyroidism with Dyslipidemia and Increased Carotid Intima-Media Thickness in Children. ( Akın, A; Demir, V; Haspolat, YK; Unal, E; Yıldırım, R; Yildiz, İ, 2017) |
| " We evaluated the association of thyroid-stimulating hormone (TSH) and free thyroxine with incident dementia using Cox models adjusted for age, sex, cardiovascular risk factors, and education." | 3.83 | Thyroid function and the risk of dementia: The Rotterdam Study. ( Bos, D; Chaker, L; Dehghan, A; Franco, OH; Hofman, A; Ikram, MA; Korevaar, TI; Koudstaal, PJ; Peeters, RP; van der Lugt, A; Vernooij, MW; Wolters, FJ, 2016) |
| "Compared to patients only taking l-thyroxine, those using liothyronine had no increased risk of cardiovascular disease [hazard ratio (HR) 1·04; 95% CI 0·70-1·54], atrial fibrillation (HR 0·91: 0·47-1·75), or fractures (HR 0·79: 0·49-1·27) after adjusting for age." | 3.83 | Liothyronine use in a 17 year observational population-based study - the tears study. ( Donnelly, LA; Leese, GP; Soto-Pedre, E, 2016) |
| " In the present investigation, effects of periplogenin-3- O-D-glucopyranosyl (1→6)(1→4)-D-cymaropyranoside, isolated from the vegetable, LAGENARIA SICERARIA, in L-thyroxine (L-T₄)-induced hyperthyroidism and in related cardiovascular abnormalities have been revealed in Wistar albino rats." | 3.77 | Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems. ( Kar, A; Panda, S, 2011) |
| "Controversy surrounds the issue of whether levothyroxine treatment improves lipid profile in patients with subclinical hypothyroidism (SHT)." | 3.75 | [Effect of treatment with levothyroxine in the lipid profile of the patients with subclinical hypothyroidism]. ( Prats Julià, M, 2009) |
| "Chronic iodine deficiency (ID) increases thyrotropin (TSH) concentrations and produces a thyroid hormone pattern consistent with subclinical hypothyroidism (ScH)." | 3.75 | Iodine treatment in children with subclinical hypothyroidism due to chronic iodine deficiency decreases thyrotropin and C-peptide concentrations and improves the lipid profile. ( Aeberli, I; Bridson, J; Chaouki, N; Grimci, L; Jooste, PL; Mbhenyane, X; Melse-Boonstra, A; Zimmermann, MB, 2009) |
| " Fasting TSH, free thyroxine (FT4), insulin, glucose, and the level of insulin resistance, estimated by the homeostasis model assessment for insulin resistance (HOMA-IR) were measured." | 3.75 | Thyroid stimulating hormone is associated with metabolic syndrome in euthyroid postmenopausal women. ( Ahn, KH; Cho, GJ; Hong, SC; Hur, JY; Kim, SH; Kim, T; Kim, YT; Lee, KW; Park, HT; Shin, JH, 2009) |
| "To investigate the clinical relevance of l-thyroxine (l-T(4)) substitution therapy in borderline hypothyroidism." | 3.74 | Cardiac effects of L-thyroxine administration in borderline hypothyroidism. ( Cambuli, VM; Deidda, M; Mariotti, S; Mercuro, G; Pigliaru, F; Putzu, C; Vargiu, S; Zoncu, S, 2008) |
| " After L: -thyroxine, CFR increased significantly in overt and subclinical hypothyroidism with respect to the baseline measurements (P < 0." | 3.74 | Coronary flow reserve after L-thyroxine therapy in Hashimoto's thyroiditis patients with subclinical and overt hypothyroidism. ( Bugra, Z; Cimen, AO; Elitok, A; Kasikcioglu, E; Kurt, R; Mercanoglu, F; Oflaz, H; Onur, I; Ozbey, N; Pamukcu, B; Sen, F; Turkmen, K, 2007) |
| "Cardiovascular disease has been reported to be more common in patients with elevated levels of TSH and with normal thyroxine levels, termed subclinical hypothyroidism (SCH)." | 3.73 | Serum biomarkers for cardiovascular inflammation in subclinical hypothyroidism. ( Geesey, ME; Hueston, WJ; King, DE, 2005) |
| "To evaluate cardiovascular functionality in patients with thyroid cancer, we have performed echocardiography and ambulatory blood pressure monitoring in 19 women with differentiated thyroid carcinoma during thyroxine withdrawal, at three time points: the last day on TSH-suppressive thyroxine doses (subclinical or mild hyperthyroidism), 4-7 days after withdrawal (normal free thyroxine (FT4) and free triiodothyronine (FT3) levels), and before 131I whole body scanning (overt hypothyroidism)." | 3.72 | Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma. ( Barrios, V; Botella-Carretero, JI; Caballero, C; Escobar-Morreale, HF; García-Robles, R; Gómez-Bueno, M; Sancho, J, 2004) |
| "This study evaluated changes of lipids and lipoprotein (a) [Lp (a)] as atherosclerotic risk factors and the effects of levothyroxine (LT4) treatment on these parameters in patient with subclinical hypothyroidism (SH), defined by increased concentrations of thyrotropin (TSH) and normal thyroid hormone concentrations." | 3.72 | Lipid profile and lipoprotein (a) as a risk factor for cardiovascular disease in women with subclinical hypothyroidism. ( Canturk, NZ; Canturk, Z; Cetinarslan, B; Ozden, M; Tarkun, I, 2003) |
| " The aim of the present study was to assess plasma total homocysteine (tHCys) concentrations in hypo- as well as hyperthyroid patients before and after treatment, and to evaluate the role of potential determinants of plasma tHCys levels in these patients." | 3.71 | Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism. ( Blom, HJ; Diekman, MJ; Tijssen, JG; van der Put, NM; Wiersinga, WM, 2001) |
| "We found a higher plasma concentration of total homocysteine (tHcy), an independent risk factor for cardiovascular disease, in patients with hypothyroidism (mean, 16." | 3.70 | Plasma total homocysteine levels in hyperthyroid and hypothyroid patients. ( Aakvaag, A; Aanderud, S; Ericsson, UB; Lien, EA; Nedrebø, BG; Nygård, O; Refsum, H; Ueland, PM, 1998) |
| "The influence of tamoxifen on plasma lipids and lipoproteins was monitored in 46 postmenopausal and 8 premenopausal women treated for advanced breast cancer up till 6 months." | 3.67 | Tamoxifen, serum lipoproteins and cardiovascular risk. ( Bonfrer, JM; Bruning, PF; de Jong-Bakker, M; Hart, AA; Linders, D; Nooyen, WJ; van Loon, J, 1988) |
| "In acute and subacute disease the active thyroid hormones, triiodothyronine (T3) and tetraiodothyroacetic acid (tetrac), are decreased while serum-thyroxine (T4) levels tend to be slightly reduced." | 3.65 | Reduced active thyroid hormone levels in acute illness. ( Braverman, L; Burger, A; Nicod, P; Suter, P; Vagenakis, P; Vallotton, MB, 1976) |
| "Instability of atherosclerotic plaque in hypothyroidism could cause excessive activity of the elements of innate immunity, which are characterized by the significant presence of macrophages in atherosclerotic plaques, increased nuclear factor kappa B (NFkB) expression, and elevated levels of tumor necrosis factor α (TNF-α) and matrix metalloproteinase (MMP) 9, with reduced interstitial collagen; all of them together creates inflammation milieu, resulting in plaque rupture." | 2.82 | Hypothyroidism and Risk of Cardiovascular Disease. ( Gluvic, ZM; Isenovic, ER; Obradovic, MM; Rizzo, M; Sudar-Milovanovic, EM; Zafirovic, SS, 2022) |
| "Subclinical hypothyroidism affects 5-15% of the general population, is especially prevalent in females, and may be associated with increased morbidity from cardiovascular disease, although it remains controversial." | 2.74 | Decrease of brachial-ankle pulse wave velocity in female subclinical hypothyroid patients during normalization of thyroid function: a double-blind, placebo-controlled study. ( Hiura, Y; Inaba, M; Ishimura, E; Kumeda, Y; Nagasaki, T; Nagata, Y; Nishizawa, Y; Shirakawa, K; Tahara, H; Yamada, S, 2009) |
| "Subclinical hyperthyroidism has been associated with increased risk of atrial fibrillation and osteoporosis, but the association with cardiovascular disease and death is uncertain." | 2.72 | Decision Making in Subclinical Thyroid Disease. ( Evron, JM; Papaleontiou, M, 2021) |
| "Hypothyroidism is associated with premature atherosclerosis and cardiovascular disease." | 2.71 | Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial. ( Christ-Crain, M; Guglielmetti, M; Huber, PR; Meier, C; Müller, B; Riesen, W; Staub, JJ, 2003) |
| "Hypothyroidism has been associated with atherosclerosis." | 2.71 | Hemostatic system as a risk factor for cardiovascular disease in women with subclinical hypothyroidism. ( Cantürk, NZ; Cantürk, Z; Cetinarslan, B; Duman, C; Ozden, M; Tarkun, I, 2003) |
| " Moreover, it is necessary to set parameters for evaluating the safety and effectiveness and understand which hormone (thyroxine or triiodothyronine), what dosage and at what stage of the disease should be applied." | 2.66 | [Use of thyroid hormones in the treatment of cardiovascular diseases: literature review]. ( Borisov, DV; Gubaeva, DN; Praskurnichiy, EA, 2020) |
| "Hypothyroidism is a common endocrine disorder that predominantly occurs in females." | 2.66 | Regulation of nitric oxide production in hypothyroidism. ( Bajic, VB; Essack, MM; Gluvic, ZM; Isenovic, ER; Obradovic, MM; Radak, DJ; Sudar-Milovanovic, EM; Takashi, G; Zafirovic, SS, 2020) |
| "Hypothyroidism is diagnosed biochemically, being overt primary hypothyroidism defined as serum thyroid-stimulating hormone (TSH) concentrations above and thyroxine concentrations below the normal reference range." | 2.61 | Hypothyroidism in Context: Where We've Been and Where We're Going. ( Carlé, A; Chiovato, L; Magri, F, 2019) |
| "Subclinical hypothyroidism is defined by elevated serum thyrotropin in presence of normal free thyroid hormones." | 2.55 | Subclinical hypothyroidism, lipid metabolism and cardiovascular disease. ( Delitala, AP; Delitala, G; Fanciulli, G; Maioli, M, 2017) |
| "Hypothyroidism is characterized by hypometabolism, and may be seen as a part of secondary failure due to pituitary insufficiency or tertiary due to hypothalamic disease." | 2.53 | Central hypothyroidism and its role for cardiovascular risk factors in hypopituitary patients. ( Feldt-Rasmussen, U; Klose, M, 2016) |
| "Sub-clinical hyperthyroidism is not associated with CHD or mortality from cardiovascular causes." | 2.44 | Impact of subclinical thyroid disorders on coronary heart disease, cardiovascular and all-cause mortality: a meta-analysis. ( Arora, R; Barsano, CP; Duggal, J; Maldonado, F; Molnar, J; Singh, S, 2008) |
| "In the treatment of differentiated thyroid cancer, requiring long-term check-ups and visits as well as administration of high doses of levothyroxine (TSH - thyroid-stimulating hormone - suppression), also in elderly patients, telemedicine seems particularly indicated." | 2.44 | Thyroid cancer: possible role of telemedicine. ( Gibelli, B; Gibelli, G; Nani, F, 2008) |
| "Subclinical hypothyroidism is also associated with the risk of progression to overt hypothyroidism and with the risk of neuropsychiatric effects." | 2.44 | [Subclinical hypothyroidism]. ( Krysiak, R; Marek, B; Okopień, B, 2008) |
| "Hypothyroidism is a common disease that is often undiagnosed or misdiagnosed because the signs and symptoms are often confused with other conditions." | 2.44 | Evaluating and treating the patient with hypothyroid disease. ( Hennessey, JV; Scherger, JE, 2007) |
| "Subclinical hypothyroidism has direct but subtle effects on the heart function, on the peripheral vascular resistance, and is associated with a mild elevation of LDL-cholesterol levels; all abnormalities may be partly reversed by a thyroxine supplementation." | 2.43 | [Is subclinical hypothyroidism a cardiovascular risk factor?]. ( Goichot, B; Grunenberger, F; Luca, F; Schlienger, JL; Vinzio, S, 2006) |
| "The adverse health effects of thyrotoxicosis have been carefully documented and most practitioners are familiar with the clinical consequences for the patient." | 2.40 | Adverse effects of thyroid hormones. ( Williams, JB, 1997) |
| " We used stratified analysis and cubic restricted analysis to investigate the dose-response relationship of individual serum biomarkers and the CVD incident." | 1.56 | Associations of multiple serum biomarkers and the risk of cardiovascular disease in China. ( Hou, C; Hou, Q; Liu, W; Su, W; Yao, H; Yi, J, 2020) |
| "Subclinical hypothyroidism affects 4." | 1.56 | Subclinical hypothyroidism: To treat or not to treat? ( Allen, S; Simon, C; Weidman-Evans, E, 2020) |
| "Thyroid disease and metabolic syndrome are both associated with cardiovascular disease." | 1.51 | The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults. ( Jeon, YK; Kim, BH; Kim, EH; Kim, IJ; Kim, JH; Kim, JM; Kim, M; Kim, SS; Kim, YK; Lee, H, 2019) |
| "Plasma PRCP levels are elevated in type 2 diabetes (T2D) mellitus and cardiovascular diseases." | 1.46 | Altered Prolylcarboxypeptidase Expression and Function in Response to Different Risk Factors of Diabetes. ( Floyd, L; Shariat-Madar, Z; Tabrizian, T, 2017) |
| "Inflammation is a major risk factor for cardiovascular complications." | 1.43 | Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. ( Abbas, AM; Sakr, HF, 2016) |
| "In the setting of differentiated thyroid cancer (DTC) management, < 0." | 1.42 | Risk-benefit ratio for TSH- suppressive Levothyroxine therapy in differentiated thyroid cancer. ( Do Cao, C; Wémeau, JL, 2015) |
| "Overt hypothyroidism is associated with an increased risk for developing cardiovascular disease." | 1.39 | Changes in metabolic and cardiovascular risk factors before and after treatment in overt hypothyroidism. ( Aytan, P; Kutluturk, F; Ozturk, B; Tasliyurt, T; Yelken, BM; Yılmaz, A; Yuce, S, 2013) |
| "The incidence of differentiated thyroid cancer is increasing in young adults and females in Korea." | 1.36 | Endothelial function is not changed during short-term withdrawal of thyroxine in patients with differentiated thyroid cancer and low cardiovascular risk. ( Chang, HJ; Cho, BY; Choi, DJ; Choi, SH; Jang, HC; Kim, KW; Lim, S; Park, DJ; Park, KU; Park, YJ, 2010) |
| "The metabolic syndrome was defined according to National Cholesterol Education Program's Adult Treatment Panel III criteria." | 1.34 | Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects. ( Bakker, SJ; Gans, RO; Links, TP; Roos, A; Wolffenbuttel, BH, 2007) |
| "Subclinical hypothyroidism is defined as an elevated serum thyroid-stimulating hormone (TSH) level in the face of normal free thyroid hormone values." | 1.33 | Does treating subclinical hypothyroidism improve markers of cardiovascular risk? ( Caraccio, N; Dardano, A; Monzani, F, 2006) |
| "Subclinical hypothyroidism is also associated with an increase risk of cardiovascular disease." | 1.32 | Thyroid dysfunction and their relation to cardiovascular risk factors such as lipid profile, hsCRP, and waist hip ratio in Korea. ( Jung, CH; Kang, JH; Kim, BS; Kim, H; Kim, SW; Lee, MH; Lee, WY; Park, JR; Rhee, EJ; Shin, HS; Sung, KC, 2003) |
| "Hypothyroidism is a common condition and recent epidemiological studies demonstrated that up to 10 percent of subjects may display its subclinical form." | 1.32 | Hypothyroidism and cardiovascular disease: role of new risk factors and coagulation parameters. ( Bruckert, E; Jublanc, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (8.02) | 18.7374 |
| 1990's | 9 (4.81) | 18.2507 |
| 2000's | 59 (31.55) | 29.6817 |
| 2010's | 77 (41.18) | 24.3611 |
| 2020's | 27 (14.44) | 2.80 |
| Authors | Studies |
|---|---|
| Evron, JM | 2 |
| Papaleontiou, M | 2 |
| van Vliet, NA | 1 |
| Bos, MM | 1 |
| Thesing, CS | 1 |
| Chaker, L | 5 |
| Pietzner, M | 1 |
| Houtman, E | 1 |
| Neville, MJ | 1 |
| Li-Gao, R | 1 |
| Trompet, S | 2 |
| Mustafa, R | 1 |
| Ahmadizar, F | 1 |
| Beekman, M | 1 |
| Bot, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-modal Effects of Thyroid Hormone Replacement for Untreated Older Adults With Subclinical Hypothyroidism; a Randomised Placebo-controlled Trial[NCT01660126] | Phase 4 | 737 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| Desiccated Thyroid Extract Compared to Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-blind, Crossover Study.[NCT01739972] | 180 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism[NCT02500342] | Phase 4 | 276 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Gender-Specific Effects of Physiologic GH Administration on Cardiovascular Risk Factors in Women With Growth Hormone Deficiency[NCT00136032] | 63 participants (Actual) | Interventional | 2002-01-31 | Completed | |||
| Phase 4 Study of Recombinant GH on Intima-Media Thickness at Common Carotids and on Cardiovascular Risk Factors in Hypopituitary Patients[NCT00462475] | 20 participants (Actual) | Observational | 1996-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
52 reviews available for thyroxine and Cardiovascular Diseases
| Article | Year |
|---|---|
Decision Making in Subclinical Thyroid Disease.
Topics: Age Factors; Atrial Fibrillation; Cardiovascular Diseases; Clinical Decision-Making; Cognition Disor | 2021 |
The impact of the management strategies for patients with subclinical hypothyroidism on long-term clinical outcomes: An umbrella review.
Topics: Adult; Cardiovascular Diseases; Humans; Hypothyroidism; Quality of Life; Systematic Reviews as Topic | 2022 |
Hypothyroidism and Risk of Cardiovascular Disease.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Plaque, Atherosclero | 2022 |
Cardiovascular outcomes in subclinical thyroid disease: an update.
Topics: Atrial Fibrillation; Cardiovascular Diseases; Humans; Hypothyroidism; Middle Aged; Prospective Studi | 2023 |
Hypothyroidism in Context: Where We've Been and Where We're Going.
Topics: Adult; Cardiovascular Diseases; Depression; Female; Humans; Hypothyroidism; Thyrotropin; Thyroxine | 2019 |
Regulation of nitric oxide production in hypothyroidism.
Topics: Animals; Biomarkers; Cardiovascular Diseases; Humans; Hypothyroidism; Lipid Metabolism; Nitric Oxide | 2020 |
Effects of oral contraceptives on thyroid function and vice versa.
Topics: Blood Coagulation; Cardiovascular Diseases; Contraception; Contraceptives, Oral; Drug Interactions; | 2020 |
Levothyroxine for the Treatment of Subclinical Hypothyroidism and Cardiovascular Disease.
Topics: Animals; Cardiovascular Diseases; Humans; Hypothyroidism; Thyroxine | 2020 |
[Use of thyroid hormones in the treatment of cardiovascular diseases: literature review].
Topics: Animals; Cardiovascular Diseases; Humans; Myocardial Infarction; Thyroid Hormones; Thyroxine; Triiod | 2020 |
Subclinical hypothyroidism: Should we treat?
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Humans; Hypothyroidism; Mental Disorders; Metabolic | 2017 |
Effect of Thyroxin Treatment on Carotid Intima-Media Thickness (CIMT) Reduction in Patients with Subclinical Hypothyroidism (SCH): a Meta-Analysis of Clinical Trials.
Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; Clinical Trials as Topic; Humans; Hypothyro | 2017 |
Thyroid Function and Dysfunction in Relation to 16 Cardiovascular Diseases.
Topics: Atrial Fibrillation; Cardiovascular Diseases; Databases, Factual; Genetic Predisposition to Disease; | 2019 |
Thyroid Hormone Suppression Therapy.
Topics: Cardiovascular Diseases; Humans; Hyperthyroidism; Thyroid Neoplasms; Thyrotropin; Thyroxine | 2019 |
Thyroid disease and vascular risk.
Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Myocardial Infarction; Thyroxine | 2014 |
Subclinical hypothyroidism: summary of evidence in 2014.
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Mental Disorde | 2014 |
Low-normal thyroid function and novel cardiometabolic biomarkers.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Carrier Proteins; Cholesterol; Female; Humans; Insulin Re | 2015 |
Low-normal thyroid function and the pathogenesis of common cardio-metabolic disorders.
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Cholesterol, LDL; Humans; Hypothyroidism; Insulin Re | 2015 |
Nitric Oxide as a Marker for Levo-Thyroxine Therapy in Subclinical Hypothyroid Patients.
Topics: Animals; Biomarkers; Cardiovascular Diseases; Humans; Hypothyroidism; Nitric Oxide; Risk Factors; Th | 2016 |
Subclinical hypothyroidism in childhood - current knowledge and open issues.
Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic; | 2016 |
Central hypothyroidism and its role for cardiovascular risk factors in hypopituitary patients.
Topics: Cardiovascular Diseases; Humans; Hypopituitarism; Hypothyroidism; Risk Factors; Thyroxine | 2016 |
Subclinical hypothyroidism, lipid metabolism and cardiovascular disease.
Topics: Blood Pressure; Cardiovascular Diseases; Carotid Intima-Media Thickness; Humans; Hypothyroidism; Lip | 2017 |
Evaluating and treating the patient with hypothyroid disease.
Topics: Adult; Algorithms; Cardiovascular Diseases; Clinical Protocols; Comorbidity; Disease Progression; Dr | 2007 |
[Subclinical hypothyroidism].
Topics: Atherosclerosis; Cardiovascular Diseases; Comorbidity; Disease Progression; Humans; Hypothyroidism; | 2008 |
Thyroid cancer: possible role of telemedicine.
Topics: Age Factors; Aged; Cardiovascular Diseases; Electrocardiography; Humans; Hyperthyroidism; Magnetic R | 2008 |
Thyroid replacement therapy and heart failure.
Topics: Animals; Cardiovascular Diseases; Diiodothyronines; Disease Models, Animal; Glomerular Filtration Ra | 2010 |
[Potential risks of the adverse effects of thyrotropin suppression in differentiated thyroid carcinoma].
Topics: Adenocarcinoma, Follicular; Aged; Bone Remodeling; Carcinoma, Papillary; Cardiovascular Diseases; Co | 2011 |
New insights into subclinical hypothyroidism and cardiovascular risk.
Topics: Animals; Cardiovascular Diseases; Hemostasis; Humans; Hypothyroidism; Risk Factors; Thyroxine | 2011 |
Subclinical thyroid disease.
Topics: Atrial Fibrillation; Cardiovascular Diseases; Comorbidity; Diagnosis, Differential; Disease Progress | 2012 |
[Subclinical thyroid disease].
Topics: Cardiovascular Diseases; Humans; Hyperthyroidism; Hypothyroidism; Prevalence; Risk Factors; Thyroxin | 2012 |
[Treatment with L-thyroxine for differentiated thyroid carcinoma].
Topics: Cardiovascular Diseases; Humans; Osteoporosis; Thyroid Neoplasms; Thyrotropin; Thyroxine | 2001 |
Subclinical hypothyroidism in women: who to treat.
Topics: Age Factors; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Infertility, Female; Pregnancy | 2002 |
Cardiovascular and medical ramifications of treatment of subclinical hypothyroidism.
Topics: Adult; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Muscular Diseases; Pregnancy; | 2003 |
[Syndrome of non-thyroid pathology in patients with cardiovascular diseases (review)].
Topics: Anti-Arrhythmia Agents; Cardiovascular Diseases; Euthyroid Sick Syndromes; Humans; Thyroxine; Triiod | 2003 |
[Levothyroxine poisoning: clinical manifestations and therapeutic management].
Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cardiovascular Diseases; Child; Cholestyramine Resi | 2004 |
Subclinical hyperthyroidism: clinical features and treatment options.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Cardiovascular Diseases; Female; Humans; Hyperthyroid | 2005 |
Subclinical hypothyroidism and cardiovascular risk: a reason to treat?
Topics: Cardiovascular Diseases; Female; Homocysteine; Humans; Hypothyroidism; Lipids; Male; Risk Factors; T | 2004 |
Hypothyroidism and cardiovascular disease.
Topics: Amiodarone; Cardiovascular Agents; Cardiovascular Diseases; Drug Interactions; Humans; Hypothyroidis | 2005 |
[Is subclinical hypothyroidism a cardiovascular risk factor?].
Topics: Cardiovascular Diseases; Cholesterol, LDL; Cross-Sectional Studies; France; Humans; Hypothyroidism; | 2006 |
Impact of subclinical thyroid disorders on coronary heart disease, cardiovascular and all-cause mortality: a meta-analysis.
Topics: Cardiovascular Diseases; Cause of Death; Coronary Artery Disease; Humans; Hyperthyroidism; Hypothyro | 2008 |
Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence?
Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation Disorders; Cardiovascular Diseases; Humans; Hyperc | 2007 |
The clinical significance of subclinical thyroid dysfunction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Calcification, Physiologic; Cardiovascular Diseas | 2008 |
[New therapeutic possibilities of propranolol].
Topics: Antithyroid Agents; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; | 1984 |
Complications of acute respiratory failure.
Topics: Acute Disease; Barotrauma; Cardiovascular Diseases; Gastrointestinal Diseases; Hematologic Diseases; | 1983 |
[Subclinical hypothyroidism].
Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Thyroxine | 1995 |
Adverse effects of thyroid hormones.
Topics: Aging; Cardiovascular Diseases; Clinical Trials as Topic; Euthyroid Sick Syndromes; Female; Humans; | 1997 |
Controversial aspects of thyroid disease.
Topics: Cardiovascular Diseases; Graves Disease; Humans; Iodine Radioisotopes; Patient Compliance; Smoking; | 1999 |
Conjugated estrogens--the natural SERMs.
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Cardiovascular Diseases; Dihydrotestosterone; Equilin; | 1999 |
Subclinical thyrotoxicosis.
Topics: Cardiovascular Diseases; Diagnosis, Differential; Disease Progression; Humans; Hyperthyroidism; Oste | 2001 |
Atrial natriuretic peptides in pathophysiological diseases.
Topics: Acute Kidney Injury; Animals; Arrhythmias, Cardiac; Ascites; Atrial Natriuretic Factor; Cardiovascul | 2001 |
["Subclinical" thyroid disease].
Topics: Cardiovascular Diseases; Diagnosis, Differential; Humans; Hyperlipidemias; Hypothyroidism; Risk Fact | 2002 |
[Thyroxine binding protein, free thyroxine and triiodothyronine--interpretation of the test results].
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Child; Diabetes Mellitus; Female; Humans; Infectio | 1973 |
Hemophilia. Current concepts in management.
Topics: Adrenal Cortex Hormones; Adult; Analgesics; Antifibrinolytic Agents; Blood Transfusion; Cardiovascul | 1972 |
8 trials available for thyroxine and Cardiovascular Diseases
| Article | Year |
|---|---|
Plasma free thyroxine in the upper quartile is associated with an increased incidence of major cardiovascular events in older men that do not have thyroid dysfunction according to conventional criteria.
Topics: Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Follow-Up Studies; Humans; Incidence; | 2018 |
Decrease of brachial-ankle pulse wave velocity in female subclinical hypothyroid patients during normalization of thyroid function: a double-blind, placebo-controlled study.
Topics: Aged; Ankle Joint; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Double-Blind Metho | 2009 |
The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomized, double-blind, crossover study.
Topics: Adult; Aged; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cross-Over Studies; Dietar | 2011 |
Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial.
Topics: Aged; Analysis of Variance; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional | 2003 |
Hemostatic system as a risk factor for cardiovascular disease in women with subclinical hypothyroidism.
Topics: Adult; Blood Pressure; Cardiovascular Diseases; Female; Fibrinolysis; Hemostasis; Humans; Hypothyroi | 2003 |
The effect of L-thyroxine replacement therapy on lipid based cardiovascular risk in subclinical hypothyroidism.
Topics: Adult; Body Mass Index; Cardiovascular Diseases; Cholesterol; Female; Humans; Hypothyroidism; Lipid | 2004 |
The beneficial effect of L-thyroxine on cardiovascular risk factors, endothelial function, and quality of life in subclinical hypothyroidism: randomized, crossover trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthropometry; Body Mass Index; Body Weight; Brachial Ar | 2007 |
Risk factors for cardiovascular disease in women with subclinical hypothyroidism.
Topics: Adult; Blood Pressure; Cardiovascular Diseases; Cholesterol; Female; Homocysteine; Humans; Hypothyro | 2002 |
127 other studies available for thyroxine and Cardiovascular Diseases
| Article | Year |
|---|---|
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Humans; Lipids; Male; Mendelian Randomization Analysis | 2021 |
Higher Free Triiodothyronine Is Associated With Higher HDL Particle Concentration and Smaller HDL Particle Size.
Topics: Cardiovascular Diseases; Cross-Sectional Studies; Humans; Particle Size; Sexually Transmitted Diseas | 2022 |
Association of Thyroid Hormone Treatment Intensity With Cardiovascular Mortality Among US Veterans.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Retrosp | 2022 |
A Cross-Sectional Study Examining the Parametric Thyroid Feedback Quantile Index and Its Relationship with Metabolic and Cardiovascular Diseases.
Topics: Adult; Atrial Fibrillation; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Typ | 2022 |
FT3/FT4 ratio is correlated with all-cause mortality, cardiovascular mortality, and cardiovascular disease risk: NHANES 2007-2012.
Topics: Cardiovascular Diseases; Cardiovascular System; Humans; Nutrition Surveys; Retrospective Studies; Th | 2022 |
Editorial: The effects of circulating non-sex hormones in cardiovascular disease.
Topics: Cardiovascular Diseases; Humans; Thyroxine; Triiodothyronine | 2022 |
Impact of Thyroid Function on the Prevalence and Mortality of Metabolic Dysfunction-Associated Fatty Liver Disease.
Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Non-alcoholic Fatty Liver Disease; Nutrition Survey | 2023 |
J-shaped association of free triiodothyronine to free thyroxine ratio with 5-year mortality among patients with chronic kidney disease: a prospective cohort study.
Topics: Cardiovascular Diseases; Humans; Nutrition Surveys; Prospective Studies; Renal Insufficiency, Chroni | 2023 |
Lower free triiodothyronine levels are associated with higher all-cause and cardiovascular mortality in people with diabetes-NHANES 2007-2012.
Topics: Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus; Humans; Nutrition Surveys; Retros | 2023 |
Thyroid function test variability and cardiovascular morbidity in hyperthyroidism.
Topics: Antithyroid Agents; Cardiovascular Diseases; Graves Disease; Humans; Hyperthyroidism; Male; Retrospe | 2023 |
Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Fractures, Bone; Humans; Hypothyroidism; Longitudinal | 2019 |
Thyroid function and life expectancy with and without noncommunicable diseases: A population-based study.
Topics: Aged; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Life Expectancy; Life Tables; Male | 2019 |
The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats.
Topics: Aldosterone; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Cardiovascular Diseases | 2020 |
Pharmacologically induced thyreopathy in patients with cardiovascular disease.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Diseases; Humans; Hyperthyroidism; Hypothyroidism | 2020 |
Impaired breathing, sleeping, vitality, and depression, and negative impact of L-T4 treatment characterize health-related quality of life in older people with stable CVD.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Depression; Female; Humans; Male; Quality of Life; | 2020 |
Subclinical hypothyroidism: To treat or not to treat?
Topics: Aged; Asymptomatic Diseases; Autoantigens; Biomarkers; Cardiovascular Diseases; Diagnosis, Different | 2020 |
Thyroid function and risk of all-cause and cardiovascular mortality: a prospective population-based cohort study.
Topics: Adult; Aged; Cardiovascular Diseases; Cohort Studies; Female; Humans; Male; Middle Aged; Prospective | 2021 |
Associations of multiple serum biomarkers and the risk of cardiovascular disease in China.
Topics: Age Factors; Aged; Biomarkers; Cardiovascular Diseases; Case-Control Studies; China; Cholesterol, LD | 2020 |
Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Double-Blind Method; Europe; Female; Follow-Up Stu | 2021 |
Usefulness of FT3 to FT4 Ratio to Predict Mortality in Euthyroid Patients With Prior Cardiovascular Events Undergoing PCI: Five-Year Findings From a Large Single-Center Cohort Study.
Topics: Biomarkers; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutane | 2021 |
Editorial: Levothyroxine Therapy in Patients With Hypothyroidism.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Drug Compounding; Drug Interactions; Female | 2021 |
Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; | 2017 |
[Thyroid status peculiarities of elderly patients 5 years after operation depending on the volume of surgical intervention].
Topics: Aged; Cardiovascular Diseases; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Male; Mi | 2016 |
Childhood thyroid function, body composition and cardiovascular function.
Topics: Blood Pressure; Body Composition; Cardiovascular Diseases; Child; Child, Preschool; Cohort Studies; | 2017 |
The Relationship between Subclinical Thyroid Disease and Cardiovascular Disease Risk Score in Koreans.
Topics: Adult; Cardiovascular Diseases; Cohort Studies; Female; Humans; Male; Middle Aged; Nutrition Surveys | 2017 |
THYROID HORMONE REPLACEMENT REDUCES THE RISK OF CARDIOVASCULAR DISEASES IN DIABETIC NEPHROPATHY PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM.
Topics: Aged; Asymptomatic Diseases; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathi | 2018 |
Association of Hypothyroidism With All-Cause Mortality: A Cohort Study in an Older Adult Population.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cohort Studies; Comorbidity; Female; Hormone Repla | 2018 |
Relationship between thyroid function and elevated blood pressure in euthyroid adults.
Topics: Adult; Blood Pressure Determination; Cardiovascular Diseases; China; Cross-Sectional Studies; Female | 2018 |
Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Follow-Up Studies; Hear | 2019 |
Heart rate response to graded exercise test of elderly subjects in different ranges of TSH levels.
Topics: Age Factors; Aged; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Exercise; Exer | 2018 |
Thyroid Function and Cardiovascular Disease: The Mediating Role of Coagulation Factors.
Topics: ADAMTS13 Protein; Aged; Aged, 80 and over; Blood Coagulation; Cardiovascular Diseases; Female; Fibri | 2019 |
The Relationship between Thyroid Function and Different Obesity Phenotypes in Korean Euthyroid Adults.
Topics: Adult; Aged; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Iodi | 2019 |
How selective are the new guidelines for treatment of subclinical hypothyroidism for patients with thyrotropin levels at or below 10 mIU/L?
Topics: Adult; Aged; Autoantibodies; Brazil; Cardiovascular Diseases; Female; Follow-Up Studies; Hormone Rep | 2013 |
Cardiovascular effects of thyroid disease.
Topics: Animals; Antithyroid Agents; Cardiovascular Diseases; Cat Diseases; Cats; Dog Diseases; Dogs; Hypert | 2013 |
The Brazilian consensus for the clinical approach and treatment of subclinical hypothyroidism in adults: recommendations of the thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brazil; Cardiovascular Diseases; Evidence-Based Medicine | 2013 |
Free thyroxine (FT4) and anemia in relation to drinking status of Japanese men: the Nagasaki islands study.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Anemia, Hypochromic; Cardiovascular Di | 2013 |
Central hypothyroidism and its replacement have a significant influence on cardiovascular risk factors in adult hypopituitary patients.
Topics: Adult; Aged; Blood Glucose; Body Composition; Body Mass Index; Cardiovascular Diseases; Female; Horm | 2013 |
Changes in metabolic and cardiovascular risk factors before and after treatment in overt hypothyroidism.
Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Risk Factors; Thyrotropin; Thyroxine | 2013 |
The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction, and body height: the Tromsø study.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Body Height; Cardiovascular Diseases; Diabetes Mel | 2014 |
Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects.
Topics: Adult; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Humans; Inter | 2014 |
Thyroid function tests and mortality in aged hospitalized patients: a 7-year prospective observational study.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cross-Sectional Studies; Female; Follow-Up | 2013 |
Plasma fetuin-A levels are reduced in patients with hypothyroidism.
Topics: Adolescent; Adult; alpha-2-HS-Glycoprotein; Cardiovascular Diseases; Female; Humans; Hypothyroidism; | 2014 |
Maternal thyroid hormones during pregnancy, childhood adiposity and cardiovascular risk factors: the Generation R Study.
Topics: Adiposity; Body Mass Index; Cardiovascular Diseases; Child; Child, Preschool; Female; Humans; Infant | 2014 |
Effect of iodothyronine hormone status on doxorubicin related cardiotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiovascular Diseases; Creatine Kinase | 2013 |
[Levothyroxine and generics: current reflections].
Topics: Cardiovascular Diseases; Drugs, Generic; Female; Humans; Hypothyroidism; Intestinal Absorption; Preg | 2014 |
Serum free thyroxine levels are positively associated with arterial stiffness in the SardiNIA study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aorta; Atherosclerosis; Body Mass Index; Cardiovascular | 2015 |
Effects of restoration of the euthyroid state on epicardial adipose tissue and carotid intima media thickness in subclinical hypothyroid patients.
Topics: Adipose Tissue; Adult; Cardiovascular Diseases; Carotid Intima-Media Thickness; Female; Hormone Repl | 2015 |
[The incidence of hypothyroidism symptoms and risk factors for cardiovascular events in subclinical hypothyroidism].
Topics: Adult; Blood Glucose; Blood Pressure Determination; Body Mass Index; Cardiovascular Diseases; Choles | 2014 |
Pulsatility index in carotid arteries is increased in levothyroxine-treated Hashimoto disease.
Topics: Adult; Cardiovascular Diseases; Carotid Artery, Common; Carotid Artery, Internal; Carotid Intima-Med | 2015 |
Low serum free thyroxine concentrations associate with increased arterial stiffness in euthyroid subjects: a population-based cross-sectional study.
Topics: Aged; Ankle Brachial Index; Autoantibodies; Autoantigens; Cardiovascular Diseases; China; Cross-Sect | 2015 |
Cardiac autonomic dysfunction in young obese males is not associated with disturbances in pituitary-thyroid axis hormones.
Topics: Autonomic Nervous System; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Electrocar | 2015 |
Risk-benefit ratio for TSH- suppressive Levothyroxine therapy in differentiated thyroid cancer.
Topics: Aged; Atrial Fibrillation; Bone Diseases; Cardiovascular Diseases; Female; Humans; Hyperthyroidism; | 2015 |
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism.
Topics: Animals; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Hypothyroidism; Inflammation; Inte | 2016 |
Liothyronine use in a 17 year observational population-based study - the tears study.
Topics: Antipsychotic Agents; Atrial Fibrillation; Cardiovascular Diseases; Cohort Studies; Fractures, Bone; | 2016 |
Should We Treat for Subclinical Hypothyroidism?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Topics: Adult; Cardiovascular Diseases; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Practic | 2016 |
Thyrotropin Levels Are Associated with Cardiometabolic Risk Factors in Euthyroid Adolescents.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Cohort Studies; Cross-Sectional Studies; Dys | 2016 |
Thyroid function and the risk of dementia: The Rotterdam Study.
Topics: Aged; Brain; Cardiovascular Diseases; Cross-Sectional Studies; Dementia; Follow-Up Studies; Humans; | 2016 |
FREE THYROID HORMONES AND MORTALITY IN CAUCASIANS UNDERGOING ANGIOGRAPHY: THE LUDWIGSHAFEN RISK AND CARDIOVASCULAR HEALTH (LURIC) STUDY.
Topics: Aged; Aged, 80 and over; Angiography; Cardiovascular Diseases; Female; Follow-Up Studies; Germany; H | 2017 |
Association of Subclinical Hypothyroidism with Dyslipidemia and Increased Carotid Intima-Media Thickness in Children.
Topics: Adolescent; Cardiovascular Diseases; Carotid Intima-Media Thickness; Child; Child, Preschool; Choles | 2017 |
Altered Prolylcarboxypeptidase Expression and Function in Response to Different Risk Factors of Diabetes.
Topics: Animals; Carboxypeptidases; Cardiovascular Diseases; Cell Survival; Cells, Cultured; Diabetes Mellit | 2017 |
Cardiovascular risk in chronic autoimmune thyroiditis and subclinical hypothyroidism patients. A cluster analysis.
Topics: Adult; Cardiovascular Diseases; Chronic Disease; Cluster Analysis; Echocardiography, Doppler; Female | 2017 |
Augmentation index in resistance to thyroid hormone (RTH).
Topics: Adult; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Cholesterol, LDL; Cohort Studie | 2009 |
Thyroid stimulating hormone is associated with metabolic syndrome in euthyroid postmenopausal women.
Topics: Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholesterol; Cross-Sectional Studies; Female | 2009 |
Iodine treatment in children with subclinical hypothyroidism due to chronic iodine deficiency decreases thyrotropin and C-peptide concentrations and improves the lipid profile.
Topics: Adolescent; C-Peptide; Cardiovascular Diseases; Child; Child, Preschool; Female; Humans; Hypothyroid | 2009 |
[Effect of treatment with levothyroxine in the lipid profile of the patients with subclinical hypothyroidism].
Topics: Aged; Body Mass Index; Cardiovascular Diseases; Cholesterol; Cohort Studies; Comorbidity; Dyslipidem | 2009 |
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Comorbidity; Female; Fractures, | 2010 |
Thyrotropin blood levels, subclinical hypothyroidism, and the elderly patient.
Topics: Activities of Daily Living; Aged; Biomarkers; Cardiovascular Diseases; Female; Humans; Hypothyroidis | 2009 |
Decreased serum TSH levels are not associated with mortality in the adult northeast German population.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Follow-Up Studies; Germany; Humans; Male; Middle Aged; | 2010 |
Endothelial function is not changed during short-term withdrawal of thyroxine in patients with differentiated thyroid cancer and low cardiovascular risk.
Topics: Adult; Cardiovascular Diseases; Endothelium, Vascular; Female; Heart Rate; Humans; Hypothyroidism; I | 2010 |
Frequency of subclinical thyroid dysfunction and risk factors for cardiovascular disease among women at a workplace.
Topics: Adult; Analysis of Variance; Antibodies; Blood Glucose; Brazil; C-Reactive Protein; Cardiovascular D | 2010 |
[Decrease in renal function associated with hypothyroidism].
Topics: Aged, 80 and over; Anemia; Atrophy; Cardiovascular Diseases; Comorbidity; Female; Glomerular Filtrat | 2010 |
Relationships between thyroid function and lipid status or insulin resistance in a pediatric population.
Topics: Adolescent; Blood Glucose; Cardiovascular Diseases; Child; Child, Preschool; Cholesterol; Fasting; H | 2010 |
Periplogenin, isolated from Lagenaria siceraria, ameliorates L-T₄-induced hyperthyroidism and associated cardiovascular problems.
Topics: Animals; Cardiovascular Diseases; Digitoxigenin; Humans; Hyperthyroidism; Lipid Peroxidation; Magnol | 2011 |
Relationships between serum levels of thyroid hormones and serum concentrations of asymmetric dimethylarginine (ADMA) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) in patients with Graves' disease.
Topics: Adult; Arginine; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Endot | 2011 |
[Resistant hypercholesteremia in clinical practice: new insight into the causes and methods of treatment].
Topics: Adult; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; | 2010 |
Predictors of thyroid hormone initiation in older adults: results from the cardiovascular health study.
Topics: Aged; Aged, 80 and over; Body Mass Index; Cardiovascular Diseases; Dose-Response Relationship, Drug; | 2011 |
Thyroid function and mortality in older men: a prospective study.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Follow-Up Studies; Humans; Male; Neoplasms; Thyroi | 2012 |
Serum T3 level can predict cardiovascular events and all-cause mortality rates in CKD patients with proteinuria.
Topics: Biomarkers; Cardiovascular Diseases; Cause of Death; Disease Progression; Female; Follow-Up Studies; | 2012 |
Metabolic changes enhance the cardiovascular risk with differentiated thyroid carcinoma--a case control study from Manipal Teaching Hospital of Nepal.
Topics: Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cell Differentiation; Female; Humans; Ins | 2012 |
Relationship of thyroid-stimulating hormone levels to development of dyslipidemia and determination of an ideal cut-off point to start replacement therapy.
Topics: Adult; Biomarkers; Body Mass Index; Cardiovascular Diseases; Cholesterol; Cross-Sectional Studies; D | 2012 |
[Impact of replacement therapy for subclinical hypothyroidism on cardiovascular risk markers in patients with type 2 diabetes mellitus].
Topics: Cardiovascular Diseases; Carotid Intima-Media Thickness; Cholesterol; Diabetes Mellitus, Type 2; Dis | 2012 |
Turbulencies during hypothyroidism therapy.
Topics: Aged; Blood Pressure; Cardiovascular Diseases; Female; Heart Rate; Humans; Hypothyroidism; Severity | 2002 |
[Autoimmune thyroiditis. Treatment with thyroid gland hormones in subclinical hypothyroidism or already in euthyroid state?].
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Female; Humans; Hypothyroidism; Male | 2003 |
SODIUM DEXTRO-THYROXINE THERAPY IN HYPERCHOLESTEROLEMIA.
Topics: Cardiovascular Diseases; Cholesterol; Coronary Disease; Hypercholesterolemia; Sodium; Thyroid Functi | 1963 |
PROLONGED ADMINISTRATION OF DEXTROTHYROXINE IN CARDIOVASCULAR PATIENTS.
Topics: Angina Pectoris; Cardiovascular Diseases; Cholesterol; Dextrothyroxine; Diet; Diet Therapy; Humans; | 1964 |
Lipid profile and lipoprotein (a) as a risk factor for cardiovascular disease in women with subclinical hypothyroidism.
Topics: Adult; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Es | 2003 |
Thyroid dysfunction and their relation to cardiovascular risk factors such as lipid profile, hsCRP, and waist hip ratio in Korea.
Topics: Adult; Aged; Aged, 80 and over; Body Constitution; C-Reactive Protein; Cardiovascular Diseases; Fema | 2003 |
Relationship of circulating C-reactive protein levels to thyroid status and cardiovascular risk in hyperlipidemic euthyroid subjects: low free thyroxine is associated with elevated hsCRP.
Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Humans; Hyperlipidemias; Middle Aged; Radio | 2004 |
Chronic thyrotropin-suppressive therapy with levothyroxine and short-term overt hypothyroidism after thyroxine withdrawal are associated with undesirable cardiovascular effects in patients with differentiated thyroid carcinoma.
Topics: Adult; Blood Pressure; Carcinoma, Papillary, Follicular; Cardiovascular Diseases; Cell Differentiati | 2004 |
Relation between Helicobacter pylori infection, thyroid hormone levels and cardiovascular risk factors on blood donors.
Topics: Adult; Age Factors; Autoantibodies; Blood Donors; Cardiovascular Diseases; Cholesterol; Educational | 2003 |
Hypothyroidism and cardiovascular disease: role of new risk factors and coagulation parameters.
Topics: C-Reactive Protein; Cardiovascular Diseases; Comorbidity; Coronary Disease; Endothelium, Vascular; F | 2004 |
Subclinical hypothyroidism and cardiovascular risk.
Topics: Cardiovascular Diseases; Hemostasis; Humans; Hypothyroidism; Risk Factors; Thyroxine | 2004 |
Are thyroid peroxidase antibodies associated with cardiovascular disease risk in patients with subclinical hypothyroidism?
Topics: Adult; Aged; Autoantibodies; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; E | 2005 |
The effects of thyroxine replacement on the levels of serum asymmetric dimethylarginine (ADMA) and other biochemical cardiovascular risk markers in patients with subclinical hypothyroidism.
Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Choleste | 2005 |
Arterial stiffness is increased in subjects with hypothyroidism.
Topics: Adult; Biomarkers; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Mi | 2005 |
Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type I deiodinase activity.
Topics: Aged; Brain Damage, Chronic; Cardiovascular Diseases; Cause of Death; Critical Illness; Female; Huma | 2005 |
Serum biomarkers for cardiovascular inflammation in subclinical hypothyroidism.
Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Chi-Square Dis | 2005 |
Does treating subclinical hypothyroidism improve markers of cardiovascular risk?
Topics: Cardiovascular Diseases; Cross-Sectional Studies; Humans; Hypothyroidism; Prospective Studies; Risk | 2006 |
Effects of thyroxine withdrawal in biochemical parameters and cardiac function and structure in patients with differentiated thyroid cancer.
Topics: Biomarkers; Carcinoma, Papillary, Follicular; Cardiovascular Diseases; Case-Control Studies; Creatin | 2006 |
Which thyroid-stimulating hormone level should be sought in hypothyroid patients under L-thyroxine replacement therapy?
Topics: C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Fibrin Fibrino | 2006 |
Restoration of euthyroidism does not improve cardiovascular risk factors in patients with subclinical hypothyroidism in the short term.
Topics: Adult; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Female; Homocysteine; Humans; Hypot | 2006 |
A new look at the "bowtie" gland. Recent research focuses on how thyroid hormone affects you heart's health.
Topics: Cardiovascular Diseases; Humans; Hypothyroidism; Thyrotropin; Thyroxine | 2006 |
Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects.
Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Female; Homeostasis; Human | 2007 |
Effect of levo-thyroxine replacement on non-high-density lipoprotein cholesterol in hypothyroid patients.
Topics: Adult; Aged; Apolipoprotein A-I; Apolipoproteins B; Cardiovascular Diseases; Cholesterol; Cholestero | 2007 |
Well-being, health-related quality of life and cardiovascular disease risk profile in women with subclinical thyroid disease - a community-based study.
Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case- | 2007 |
Cardiac effects of L-thyroxine administration in borderline hypothyroidism.
Topics: Adult; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Male; Middle Aged; Radiography; Thyr | 2008 |
Feasibility, accuracy, and clinical relevance of a rapid thyroid evaluation during carotid duplex ultrasonography in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Cardiovascular Diseases; Feasibility Studies; Female; Follow-U | 2007 |
Subclinical hypothyroidism is a risk factor for nephropathy and cardiovascular diseases in Type 2 diabetic patients.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; D | 2007 |
Coronary flow reserve after L-thyroxine therapy in Hashimoto's thyroiditis patients with subclinical and overt hypothyroidism.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Coronary Vessels; Echocardiography; Female; Fo | 2007 |
Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism.
Topics: Animals; Arterioles; Atrophy; Cardiovascular Diseases; Coronary Vessels; Disease Models, Animal; Dos | 2008 |
Serum sex hormone-binding globulin and osteocalcin in systemic nonthyroidal illness associated with low thyroid hormone concentrations.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Communicable Diseases; Female; | 1996 |
Evaluation of five commercial kits for free thyroxine estimation by comparison with equilibrium dialysis method in nonthyroidal illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Humans; Immunoassay; Ki | 1996 |
Plasma total homocysteine levels in hyperthyroid and hypothyroid patients.
Topics: Adult; Aged; Arteriosclerosis; Cardiovascular Diseases; Cholesterol; Creatinine; Female; Folic Acid; | 1998 |
Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Biomarkers; Cardiovascular Diseases; Creatinine; Fem | 2001 |
Mortality in elderly patients with subclinical hyperthyroidism.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Humans; Hyperthyroidism; Middle Aged; Reference Value | 2002 |
Mortality in elderly patients with subclinical hyperthyroidism.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Cholesterol; Coronary Disease; Humans; Hyperthyroidis | 2002 |
Reduced active thyroid hormone levels in acute illness.
Topics: Acute Disease; Adult; Aged; Bronchitis; Cardiovascular Diseases; Child; Female; Gastroenteritis; Hum | 1976 |
Abnormal thyroid function tests in devere non-thyroidal illness: diagnostic and pathophysiologic aspects.
Topics: Adult; Aged; Cardiovascular Diseases; Fatty Acids, Nonesterified; Female; Gastrointestinal Diseases; | 1979 |
[Hyperthyroidism in older patients].
Topics: Aged; Cardiovascular Diseases; Diagnosis, Differential; Goiter, Nodular; Graves Disease; Humans; Hyp | 1978 |
Therapeutics: recent suggestions for the treatment of hypothyroidism and diabetes mellitus.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Hypothyroidism; Phenformin; Sulfonylurea Compoun | 1975 |
Premature mortality due to cardiovascular disease in hypopituitarism.
Topics: Adenocarcinoma; Age Factors; Cardiovascular Diseases; Cause of Death; Combined Modality Therapy; Fem | 1990 |
Premature mortality due to cardiovascular disease in hypopituitarism.
Topics: Adenocarcinoma; Age Factors; Cardiovascular Diseases; Cause of Death; Combined Modality Therapy; Fem | 1990 |
Premature mortality due to cardiovascular disease in hypopituitarism.
Topics: Adenocarcinoma; Age Factors; Cardiovascular Diseases; Cause of Death; Combined Modality Therapy; Fem | 1990 |
Premature mortality due to cardiovascular disease in hypopituitarism.
Topics: Adenocarcinoma; Age Factors; Cardiovascular Diseases; Cause of Death; Combined Modality Therapy; Fem | 1990 |
Longitudinal study of thyroid function in acutely ill elderly patients using a sensitive TSH assay-defer testing until recovery.
Topics: Acute Disease; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Hospitalization; Humans; Lo | 1990 |
Severe hyperthyroidism due to neoplastic TSH hypersecretion in an old man.
Topics: Bromocriptine; Cardiovascular Diseases; Humans; Hyperthyroidism; Male; Methimazole; Middle Aged; Pit | 1989 |
[Amiodarone and thyroid function].
Topics: Adult; Aged; Amiodarone; Cardiovascular Diseases; Drug Administration Schedule; Female; Humans; Hype | 1987 |
Tamoxifen, serum lipoproteins and cardiovascular risk.
Topics: Adult; Aged; Breast Neoplasms; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, | 1988 |
Thyroid storm.
Topics: Adult; Age Factors; Body Temperature Regulation; Cardiovascular Diseases; Central Nervous System Dis | 1974 |
[Hyperlipoproteinemias: significance--diagnosis--therapy].
Topics: Adolescent; Adult; Blood Protein Disorders; Cardiovascular Diseases; Child; Child, Preschool; Choles | 1971 |