Page last updated: 2024-11-06

thyroxine and Cardiac Failure

thyroxine has been researched along with Cardiac Failure in 119 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"Systolic and diastolic heart function did not differ after treatment with levothyroxine compared with placebo in older adults with mild subclinical hypothyroidism."9.34The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial. ( Bauer, DC; Blum, MR; Buffle, E; Collet, TH; da Costa, BR; Delgiovane, C; Feller, M; Gabus, V; Gencer, B; Gussekloo, J; Kearney, P; Monney, P; Moutzouri, E; Müller, H; Rodondi, N; Stott, DJ; Sykiotis, GP; Westendorp, R, 2020)
"To assess the effect of levothyroxine (compared to placebo or no treatment) on the incidence of all-cause and CV mortality, major adverse CV events, and heart failure in patients with SCH and CHF."9.22Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review. ( Cittadini, A; Lisco, G; Triggiani, V, 2022)
"To assess whether levothyroxine treatment improves functional capacity in patients with chronic heart failure (New York Heart Association class i-iii) and subclinical hypothyroidism."9.17[Improvement in functional capacity after levothyroxine treatment in patients with chronic heart failure and subclinical hypothyroidism]. ( Angel, A; Cordero, DJ; Cortez Quiroga, GA; Curotto Grasiosi, J; Dak, M; Degregorio, A; Delgado, J; Esper, RJ; Filipini, EC; Izurieta, C; Machado, RA; Martínez Quesada, Mdel M; Peressotti, B; Rus Mansilla, C, 2013)
" Sacubitril/valsartan (LCZ696) is a new combined drug that has shown promise for the treatment of hyperthyroidism-associated heart failure; however, the underlying molecular mechanisms, including the contributions of epigenetic regulation, remain unclear."8.12Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways. ( Abdullah, DM; Alsemeh, AE; Khamis, T, 2022)
"Hypothyroidism has detrimental effects on the cardiovascular system, but controversy remains concerning the benefits of levothyroxine (L-T4) substitution in patients with heart failure (HF)."7.91Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study. ( Einfeldt, MN; Faber, J; Gislason, GH; Khalid, U; Kristensen, SL; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2019)
" Oxidative stress present in heart failure (HF) and myocardial infarction (MI) might cause Se deficiency and decreased thyroxine to triiodothyronine conversion."7.91Selenium deficiency and the dynamics of changes of thyroid profile in patients with acute myocardial infarction and chronic heart failure. ( Czubek, U; Frączek-Jucha, M; Gackowski, A; Kabat, M; Nessler, J; Szlósarczyk, B, 2019)
"Hypothyroidism, especially the subclinical form, frequently occurs in patients affected by CHF receiving amiodarone therapy."7.78Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure: role of amiodarone. ( Catanzaro, R; Ciccone, MM; Favale, S; Forleo, C; Giagulli, VA; Guastamacchia, E; Guida, P; Iacoviello, M; Licchelli, B; Monzani, F; Puzzovivo, A; Tafaro, E; Triggiani, V, 2012)
"Eight patients with amiodarone-induced thyrotoxicosis (three with type I and five with type II), mean age 66."7.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
" The aim of our study was to ascertain, whether also distinct changes within normal range of free thyroxine (fT4) would be associated with an impairment of left ventricle function in patients with chronic heart failure."7.74Even mild changes in free thyroxine could influence the degree of heart failure measured by its biological surrogates. ( Cech, J; Hrbková, J; Mayer, O; Pikner, R; Rosolová, H; Simon, J; Trefil, L, 2008)
"To investigate the potential association between serum inflammatory cytokine levels and post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure."7.74Post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure: the role of cytokines. ( Antonoglou, C; Gioka, T; Kotsiou, S; Maltezos, E; Papanas, N; Papatheodorou, K; Papazoglou, D, 2008)
"In order to explore the relationship between congestive heart failure (CHF) and serum thyroxine, we assayed serum thyroxine level in 52 patients with CHF and 28 normal persons by means of radioimmunoassay (RIA)."7.70[Changes and clinical significance of serum thyroxine level in patients with congestive heart failure]. ( Fang, Y; Fu, Q; Yan, H, 1999)
" Main outcome measures effective rate and New York Heart Association classification; Secondary outcome measures included: left ventricular ejection fraction, quality of life score, brain natriuretic peptide / N-terminal pro brain natriuretic peptide, 6-minute walk test, and adverse events."5.62Efficacy and safety of thyroxine therapy on patients with heart failure and subclinical hypothyroidism: A protocol for systematic review and meta-analysis. ( Kan, Z; Li, W; Liu, Y; Peng, M; Shi, H; Yang, T, 2021)
"Systolic and diastolic heart function did not differ after treatment with levothyroxine compared with placebo in older adults with mild subclinical hypothyroidism."5.34The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial. ( Bauer, DC; Blum, MR; Buffle, E; Collet, TH; da Costa, BR; Delgiovane, C; Feller, M; Gabus, V; Gencer, B; Gussekloo, J; Kearney, P; Monney, P; Moutzouri, E; Müller, H; Rodondi, N; Stott, DJ; Sykiotis, GP; Westendorp, R, 2020)
"To assess the effect of levothyroxine (compared to placebo or no treatment) on the incidence of all-cause and CV mortality, major adverse CV events, and heart failure in patients with SCH and CHF."5.22Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review. ( Cittadini, A; Lisco, G; Triggiani, V, 2022)
"To assess whether levothyroxine treatment improves functional capacity in patients with chronic heart failure (New York Heart Association class i-iii) and subclinical hypothyroidism."5.17[Improvement in functional capacity after levothyroxine treatment in patients with chronic heart failure and subclinical hypothyroidism]. ( Angel, A; Cordero, DJ; Cortez Quiroga, GA; Curotto Grasiosi, J; Dak, M; Degregorio, A; Delgado, J; Esper, RJ; Filipini, EC; Izurieta, C; Machado, RA; Martínez Quesada, Mdel M; Peressotti, B; Rus Mansilla, C, 2013)
" The decision-making process needs to take into account the risk of levothyroxine overtreatment and the resulting adverse consequences, such as reduction of bone mineral density, heart failure, and atrial fibrillation."5.12A practical contemporary approach to decision-making on subclinical hypothyroidism. ( Sgarbi, JA; Ward, LS, 2021)
"Subclinical hypothyroidism (SCH) is an asymptomatic condition associated with increased thyroid-stimulating hormone (TSH) >4 mIU/L with normal thyroxine (T4) and triidothyronine (T3) levels."5.05The current debate over treatment of subclinical hypothyroidism to prevent cardiovascular complications. ( Chrysant, SG, 2020)
" Patients with overt or subclinical hypothyroidism should be treated with levothyroxine to improve their cardiovascular function and the potential risk of heart failure."5.01The Management of Thyroid Abnormalities in Chronic Heart Failure. ( Biondi, B, 2019)
"Reports published with the following search terms were searched:, thyroid, hypothyroidism, hyperthyroidism, subclinical hyperthyroidism, subclinical hypothyroidism, levothyroxine, triiodothyronine, antithyroid drugs, radioiodine, deiodinases, clinical symptoms, heart rate, HF, systolic function, diastolic function, systemic vascular resistance, endothelial function, amiodarone and atrial fibrillation."4.88Mechanisms in endocrinology: Heart failure and thyroid dysfunction. ( Biondi, B, 2012)
" The hazard of each outcome according to either baseline levothyroxine use or TSH-defined hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism was estimated before and after adjustment for baseline demographic and clinical characteristics and treatment allocation."4.31Thyroid Dysfunction and Cardiovascular Events in Patients With Dysglycemia. ( Gerstein, HC; Orlov, S; Paré, G; Shah, R, 2023)
"It is still not clear how the free triiodothyronine (FT3) to free thyroxine (FT4) ratio affects the prognosis of acute myocardial infarction (AMI), especially the risk of heart failure (HF) subsequent to AMI."4.31Higher Peripheral Thyroid Sensitivity Is Linked to a Lower Risk of Heart Failure After Acute Myocardial Infarction. ( Fang, S; Lang, X; Li, L; Li, Y; Li, Z; Wu, N; Xing, L; Zhang, Y; Zhao, B, 2023)
" Sacubitril/valsartan (LCZ696) is a new combined drug that has shown promise for the treatment of hyperthyroidism-associated heart failure; however, the underlying molecular mechanisms, including the contributions of epigenetic regulation, remain unclear."4.12Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways. ( Abdullah, DM; Alsemeh, AE; Khamis, T, 2022)
" Oxidative stress present in heart failure (HF) and myocardial infarction (MI) might cause Se deficiency and decreased thyroxine to triiodothyronine conversion."3.91Selenium deficiency and the dynamics of changes of thyroid profile in patients with acute myocardial infarction and chronic heart failure. ( Czubek, U; Frączek-Jucha, M; Gackowski, A; Kabat, M; Nessler, J; Szlósarczyk, B, 2019)
"Hypothyroidism has detrimental effects on the cardiovascular system, but controversy remains concerning the benefits of levothyroxine (L-T4) substitution in patients with heart failure (HF)."3.91Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study. ( Einfeldt, MN; Faber, J; Gislason, GH; Khalid, U; Kristensen, SL; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2019)
"9 mlU/l), subclinical hypothyroidism is defined as a raised TSH with normal serum free thyroxine (FT4) concentrations (9-19 pmol/l)."3.79Subclinical thyroid dysfunction and cardiac function amongst minority ethnic groups in the UK: a cross sectional study. ( Chackathayil, J; Davis, RC; Gill, PS; Hughes, E; Lip, GY; Patel, JV; Webster, C, 2013)
"Hypothyroidism, especially the subclinical form, frequently occurs in patients affected by CHF receiving amiodarone therapy."3.78Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure: role of amiodarone. ( Catanzaro, R; Ciccone, MM; Favale, S; Forleo, C; Giagulli, VA; Guastamacchia, E; Guida, P; Iacoviello, M; Licchelli, B; Monzani, F; Puzzovivo, A; Tafaro, E; Triggiani, V, 2012)
"Eight patients with amiodarone-induced thyrotoxicosis (three with type I and five with type II), mean age 66."3.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
" The aim of our study was to ascertain, whether also distinct changes within normal range of free thyroxine (fT4) would be associated with an impairment of left ventricle function in patients with chronic heart failure."3.74Even mild changes in free thyroxine could influence the degree of heart failure measured by its biological surrogates. ( Cech, J; Hrbková, J; Mayer, O; Pikner, R; Rosolová, H; Simon, J; Trefil, L, 2008)
"To investigate the potential association between serum inflammatory cytokine levels and post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure."3.74Post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure: the role of cytokines. ( Antonoglou, C; Gioka, T; Kotsiou, S; Maltezos, E; Papanas, N; Papatheodorou, K; Papazoglou, D, 2008)
"To study the relationship between the TCM Syndrome Differentiation-types of congestive heart failure (CHF) and thyroid hormones, including triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH), and atrial natriuretic peptide (ANP), as well as cardiac function parameters, including left ventricular ejection fraction (LVEF), mean velocity of circumferentid fiber shortening (mVcf) and A peak/E peak (A/E)."3.72[Study on relationship among thyroid hormone relativity and Syndrome Differentiation-types of TCM in patients with congestive heart failure]. ( Chen, J; Cheng, X; Gao, XL; Huang, S; Huang, T; Pei, Y; Sheng, L; Shi, D; Wang, L; Yan, X; Yang, A; Zhang, BZ; Zhou, J, 2004)
"In order to explore the relationship between congestive heart failure (CHF) and serum thyroxine, we assayed serum thyroxine level in 52 patients with CHF and 28 normal persons by means of radioimmunoassay (RIA)."3.70[Changes and clinical significance of serum thyroxine level in patients with congestive heart failure]. ( Fang, Y; Fu, Q; Yan, H, 1999)
"The effects of spontaneous and experimentally induced congestive heart failure on serum thyroxine (T4), 3,5,3'-triiodothyronine (T3), 3,3'5'-triiodothyronine (reverse T3), free T4, free T3 concentrations, and the serum T4 and T3 concentrations in response to administration of thyrotropin were studied."3.69Thyroid function in dogs with spontaneous and induced congestive heart failure. ( Panciera, DL; Refsal, KR, 1994)
"A case report is presented of an adolescent male who developed hypothyroidism and cardiomyopathy 6 months after he began taking lithium and imipramine for a severe conduct disorder."3.68Cardiac toxicity in an adolescent following chronic lithium and imipramine therapy. ( Dietrich, A; Mortensen, ME; Wheller, J, 1993)
"Serum total thyroxine, triiodothyronine and thyrotropin response to thyrotropin-releasing hormone were measured in 75 consecutive patients presenting to a cardiology clinic with atrial fibrillation with no obvious cardiovascular cause."3.66Occult thyrotoxicosis: a correctable cause of "idiopathic" atrial fibrillation. ( Forfar, JC; Miller, HC; Toft, AD, 1979)
"Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare entity, occurring in one per million people."2.72ENDOCRINE TUMOURS: Thyrotropin-secreting pituitary adenoma: a structured review of 535 adult cases. ( De Block, C; De Herdt, C; Philipse, E, 2021)
"Based on these findings, the observed congestive heart failure was considered as a sequel of myocardial injury caused by uncontrolled hyperthyroidism."1.91Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism. ( Chae, Y; Kang, BT; Kim, H; Koo, Y; Lee, D; Lee, H; Park, J; Yang, MP; Yun, T, 2023)
" Main outcome measures effective rate and New York Heart Association classification; Secondary outcome measures included: left ventricular ejection fraction, quality of life score, brain natriuretic peptide / N-terminal pro brain natriuretic peptide, 6-minute walk test, and adverse events."1.62Efficacy and safety of thyroxine therapy on patients with heart failure and subclinical hypothyroidism: A protocol for systematic review and meta-analysis. ( Kan, Z; Li, W; Liu, Y; Peng, M; Shi, H; Yang, T, 2021)
"Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors."1.56A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas. ( Hong, KT; Kim, GB; Kim, YH; Ko, JS; Lee, YA; Lee, YJ; Shin, CH, 2020)
"Vasoplegia has been described as a complication after cardiac surgery, particularly in patients with a poor left ventricular ejection fraction."1.46Incidence and predictors of vasoplegia after heart failure surgery. ( Beeres, SL; Berendsen, RR; Couperus, LE; de Jonge, E; Klautz, RJ; Mertens, B; Palmen, M; Schalij, MJ; Tops, LF; van Vessem, ME; Verwey, HF, 2017)
"Neonatal hyperthyroidism is usually a self-limited condition frequently associated with transplacental passage of thyroid stimulating antibodies secondary to maternal autoimmune disorders."1.40[Heart failure as early manifestation of neonatal hyperthyroidism. Case report]. ( Alvarado S, JL; Fernández V, ZA, 2014)
"In particular, cardiac failure was observed in the second fetus."1.39Antenatal management of recurrent fetal goitrous hyperthyroidism associated with fetal cardiac failure in a pregnant woman with persistent high levels of thyroid-stimulating hormone receptor antibody after ablative therapy. ( Ikenoue, S; Ishii, T; Kadohira, I; Kasuga, Y; Matsumoto, T; Minegishi, K; Miyakoshi, K; Momotani, N; Saisho, Y; Sato, S; Yoshimura, Y, 2013)
"Variably penetrant pituitary insufficiency, including this severe and atypical presentation, can be correlated with LHX4 insufficiency and highlights the role of LHX4 for pituitary development."1.38Panhypopituitarism presenting as life-threatening heart failure caused by an inherited microdeletion in 1q25 including LHX4. ( Bischof-Renner, A; Filges, I; Glanzmann, R; Günthard, J; Huber, AR; Miny, P; Potthoff, C; Röthlisberger, B; Schneider, J; Szinnai, G; Zumsteg, U, 2012)
"To analyze occurrence of thyroid dysfunction due to regular long-term intake of amiodaron (for one year), to search for predictors of amiodaron-induced hypothyroidism and thyrotoxicosis."1.33[Incidence and predictors of thyroid dysfunction caused by long-term intake of amiodaron]. ( Bakalov, SA; Golitsyn, SP; Molashenko, NV; Platonova, NM; Serdiuk, SE; Sviridenko, NIu, 2005)
"Degree of heart failure was quantified by plasma B-type natriuretic peptide (BNP), N-terminal pro-BNP (NT-proBNP) and big endothelin."1.33[Association between free thyroxin concentration and degree of heart failure in patients with chronic heart insufficiency]. ( Cech, J; Mayer, O; Pikner, R; Rosolová, H; Simon, J, 2005)
"Sick euthyroid syndrome is defined as the decrease of serum free triiodothyronine with normal free L-thyroxin and thyrotropin."1.31Heart failure accompanied by sick euthyroid syndrome and exercise training. ( Boudonas, G; Efthimiadis, A; Keskilidis, C; Lefkos, N; Psirropoulos, D; Tsapas, G; Vogas, V, 2002)
"Resolution of dilated cardiomyopathy with normalization of systolic function was achieved in five patients, and improvement from severe to mild left ventricular dysfunction was observed in two patients."1.29Congestive heart failure due to reversible cardiomyopathy in patients with hyperthyroidism. ( Challapalli, S; Patterson, C; Umpierrez, GE, 1995)
"Thyrotoxicosis has been associated with several cardiac complications, including atrial fibrillation (AF), functional cardiomyopathy, and congestive heart failure (CHF)."1.29Thyrotoxicosis-induced congestive heart failure in an urban hospital. ( Newmark, SR; Wilson, BE, 1994)
"Patients with ventricular tachycardia demonstrated significantly lower serum values of FT3 and FT3/FT4, and significantly higher values of rT3."1.29[Serum thyroid hormone levels correlate with cardiac function and ventricular tachyarrhythmia in patients with chronic heart failure]. ( Inoue, T; Maeda, T; Niwa, H; Saikawa, T; Shimoyama, N, 1993)
"Pericardial effusion was demonstrated in 15 of the patients, but disappeared during thyroxin therapy."1.28[Hypothyroid cardiomyopathy--an underdiagnosed cause of heart failure]. ( Aslaksen, BB; Gallefoss, F; Gundersen, T; Paulsen, AQ, 1990)
"Signs of congestive heart failure are absent."1.27Cardiac alterations at the myofibrillar level: is a redistribution of the myosin isoenzyme pattern decisive for cardiac failure in haemodynamic overload? ( Ebrecht, G; Jacob, R; Jörg, E; Kissling, G; Rupp, H; Takeda, N, 1984)
" A transient decrease in total T4, elevation in the T3 resin uptake and consequent increase in the free T4 index (FT4I) were seen 2-5 h after ingestion of frusemide at a chronic morning dosage of 80, 120 or 250 mg."1.27Effect of oral frusemide on diagnostic indices of thyroid function. ( Hamblin, PS; Lim, CF; Long, F; Newnham, HH; Stockigt, JR; Topliss, DJ, 1987)
"In patients with effort syndrome and hyperthyroidism, MTTs were often, but not always shortened below the control values; consequently, in case of associated heart disease, MTT-prolongation may be masked in such instances where hyperthyroidism causes MTT shortening."1.25[Minimal cardiac transit time in thyroid disorders and in the effort syndrome]. ( Becker, V; Feinendegen, LE; Schicha, H; Siebers, G; Vyska, K, 1975)

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-199027 (22.69)18.7374
1990's18 (15.13)18.2507
2000's25 (21.01)29.6817
2010's34 (28.57)24.3611
2020's15 (12.61)2.80

Authors

AuthorsStudies
Saad, NS1
Mashali, MA1
Elnakish, MT1
Hare, A1
Campbell, CM1
Kiduko, SA1
Peczkowski, KK1
Huang, AW1
Fazlollahi, F1
Torres Matias, GS1
Ahmed, AAE1
Whitson, BA1
Mokadam, NA1
Janssen, PML1
Khamis, T1
Alsemeh, AE1
Abdullah, DM1
Triggiani, V6
Cittadini, A4
Lisco, G3
Shah, R1
Orlov, S1
Paré, G1
Gerstein, HC1
Lang, X1
Zhao, B1
Fang, S1
Li, L1
Li, Z1
Wu, N1
Zhang, Y5
Xing, L1
Li, Y2
Leite, AR1
Neves, JS1
Angélico-Gonçalves, A1
Vasques-Nóvoa, F1
Saraiva, FA1
Pinho, IB1
Oliveira, AC1
Borges-Canha, M1
von Hafe, M1
Vale, C1
Lourenço, AP1
Macedo, F1
Araújo, JP1
von Hafe, P1
Almeida, J1
Ferreira, JP1
Leite-Moreira, A1
Lee, H1
Lee, D1
Park, J1
Yun, T1
Koo, Y1
Chae, Y1
Kang, BT1
Yang, MP1
Kim, H1
Turić, I1
Velat, I1
Bušić, Ž1
Čulić, V1
Nguyen, AB1
Imamura, T1
Besser, S1
Rodgers, D1
Chung, B1
Raikhelkar, J1
Kalantari, S1
Smith, B1
Sarswat, N1
LaBuhn, C1
Jeevanandam, V1
Kim, G1
Sayer, G1
Uriel, N1
Chrysant, SG1
Gencer, B2
Moutzouri, E1
Blum, MR1
Feller, M1
Collet, TH2
Delgiovane, C1
da Costa, BR1
Buffle, E1
Monney, P1
Gabus, V1
Müller, H1
Sykiotis, GP1
Kearney, P1
Gussekloo, J2
Westendorp, R1
Stott, DJ1
Bauer, DC2
Rodondi, N2
Kim, YH1
Lee, YA1
Shin, CH1
Hong, KT1
Kim, GB1
Ko, JS1
Lee, YJ1
Badran, HM1
Faheem, N1
Zidan, A1
Yacoub, MH1
Soltan, G1
Sgarbi, JA1
Ward, LS1
Shi, H1
Kan, Z1
Liu, Y1
Li, W1
Peng, M1
Yang, T1
De Herdt, C1
Philipse, E1
De Block, C1
van Vessem, ME1
Palmen, M1
Couperus, LE1
Mertens, B1
Berendsen, RR1
Tops, LF1
Verwey, HF1
de Jonge, E1
Klautz, RJ1
Schalij, MJ1
Beeres, SL1
Sato, Y1
Yoshihisa, A1
Kimishima, Y1
Kiko, T1
Watanabe, S1
Kanno, Y1
Abe, S1
Miyata, M1
Sato, T1
Suzuki, S1
Oikawa, M1
Kobayashi, A1
Yamaki, T1
Kunii, H1
Nakazato, K1
Ishida, T1
Takeishi, Y1
Flores, S1
Checchia, PA1
Drzayich Antol, D1
Waldman Casebeer, A1
Khoury, R1
Michael, T1
Renda, A1
Hopson, S1
Parikh, A1
Stein, A1
Costantino, M1
Stemkowski, S1
Bunce, M1
Nevo, N1
Abu-Abeid, S1
Hazzan, D1
Lahat, G1
Nachmani, I1
Eldar, SM1
Zhang, L1
Xia, X1
Zhong, Y1
Xie, D1
Liu, S1
Wang, X1
Tu, J1
Faconti, L1
Mills, CE1
Govoni, V1
Gu, H1
Morant, S1
Jiang, B1
Cruickshank, JK1
Webb, AJ1
Lin, J1
Wu, YJ1
Liang, X1
Ji, M1
Ying, HM1
Wang, XY1
Sun, X1
Shao, CH1
Zhan, LX1
Czamara, K1
Karnas, E1
Majka, Z1
Wojcik, T1
Zuba-Surma, EK1
Baranska, M1
Kaczor, A1
Liu, X1
Zhou, F1
Yang, Y1
Wang, W1
Niu, L1
Zuo, D1
Li, X2
Hua, H1
Zhang, B1
Kou, Y1
Guo, J1
Kong, F1
Pan, W1
Gao, D1
Meves, JM1
Sun, H1
Xue, M1
Zhang, Q1
Wang, Y2
Tang, R1
Iso, T1
Haruyama, H1
Sunaga, H1
Matsui, H1
Matsui, M1
Tanaka, R1
Umbarawan, Y1
Syamsunarno, MRAA1
Putri, M1
Yamaguchi, A1
Hanaoka, H1
Negishi, K1
Yokoyama, T1
Kurabayashi, M1
Palomo-Briones, R1
Esquivel-González, S1
Aizpuru, A1
Gómez-Hernández, N1
Casas-Flores, S1
Barba de la Rosa, AP1
Arriaga, S1
Peterson, ME1
Carothers, MA1
Gamble, DA1
Rishniw, M1
Einfeldt, MN1
Olsen, AS1
Kristensen, SL1
Khalid, U1
Faber, J1
Torp-Pedersen, C1
Gislason, GH1
Selmer, C1
Kannan, L1
Shaw, PA1
Morley, MP1
Brandimarto, J1
Fang, JC1
Sweitzer, NK1
Cappola, TP1
Cappola, AR2
Frączek-Jucha, M1
Kabat, M1
Szlósarczyk, B1
Czubek, U1
Nessler, J1
Gackowski, A1
Biondi, B2
Vasiliadis, I1
Kolovou, G1
Kolovou, V1
Giannakopoulou, V1
Boutsikou, M1
Katsiki, N1
Papadopoulou, E1
Mavrogeni, S1
Sorontila, K1
Pantos, C1
Cokkinos, DV1
Curotto Grasiosi, J1
Peressotti, B1
Machado, RA1
Filipini, EC1
Angel, A1
Delgado, J1
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Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Thyroid Hormone Replacement on Cardiac Function: a Randomized Placebo-Controlled Trial in Older Adults With Subclinical Hypothyroidism[NCT02832960]Phase 4185 participants (Actual)Interventional2016-06-30Completed
Impact of Thyroid Hormone Replacement on Progression of Atherosclerosis : a Randomized Placebo-Controlled Trial in Older Adults With Subclinical Hypothyroidism.[NCT02832934]Phase 4184 participants (Actual)Interventional2016-06-30Completed
Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypothyroidism[NCT02467244]120 participants (Actual)Observational2017-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

17 reviews available for thyroxine and Cardiac Failure

ArticleYear
Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Chronic Disease; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidism; Thyroxine

2022
Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Chronic Disease; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidism; Thyroxine

2022
Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Chronic Disease; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidism; Thyroxine

2022
Effect of levothyroxine replacement therapy in patients with subclinical hypothyroidism and chronic heart failure: A systematic review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Chronic Disease; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidism; Thyroxine

2022
The current debate over treatment of subclinical hypothyroidism to prevent cardiovascular complications.
    International journal of clinical practice, 2020, Volume: 74, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Disease Management; Female; Heart Failure; Humans; Hypothyroidism; M

2020
A practical contemporary approach to decision-making on subclinical hypothyroidism.
    Archives of endocrinology and metabolism, 2021, Nov-01, Volume: 65, Issue:1

    Topics: Aged; Aged, 80 and over; Heart Failure; Humans; Hypothyroidism; Quality of Life; Thyrotropin; Thyrox

2021
ENDOCRINE TUMOURS: Thyrotropin-secreting pituitary adenoma: a structured review of 535 adult cases.
    European journal of endocrinology, 2021, Jul-12, Volume: 185, Issue:2

    Topics: Adenoma; Atrial Fibrillation; Chemotherapy, Adjuvant; Goiter; Gonadotropins, Pituitary; Growth Hormo

2021
The Management of Thyroid Abnormalities in Chronic Heart Failure.
    Heart failure clinics, 2019, Volume: 15, Issue:3

    Topics: Disease Management; Disease Progression; Heart Failure; Hormone Replacement Therapy; Humans; Thyroid

2019
Hormone replacement therapy in heart failure.
    Current opinion in cardiology, 2015, Volume: 30, Issue:3

    Topics: Androgens; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Heart Failure; Hormone Repla

2015
Thyroid replacement therapy and heart failure.
    Circulation, 2010, Jul-27, Volume: 122, Issue:4

    Topics: Animals; Cardiovascular Diseases; Diiodothyronines; Disease Models, Animal; Glomerular Filtration Ra

2010
Mechanisms in endocrinology: Heart failure and thyroid dysfunction.
    European journal of endocrinology, 2012, Volume: 167, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease;

2012
[Role of thyroid hormones in regulation of heart function].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:1

    Topics: Arrhythmias, Cardiac; Heart; Heart Conduction System; Heart Failure; Heart Rate; Humans; Hyperthyroi

2004
Thyroid hormone and heart failure.
    Current heart failure reports, 2006, Volume: 3, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Failure; Humans; Thyroid Diseases; Thyroxine; Triiodothyro

2006
Thyroid hormone abnormalities in heart failure: possibilities for therapy.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:5

    Topics: Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Safety; Thyroid Hormones; Thyroxine; Tr

1996
Hyperthyroid heart disease.
    Clinical cardiology, 2000, Volume: 23, Issue:6

    Topics: Atrial Fibrillation; Heart; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Myocardial Contr

2000
Thyroid hormone and the cardiovascular system.
    The New England journal of medicine, 2001, Feb-15, Volume: 344, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart; Heart Diseases

2001
Atrial natriuretic peptides in pathophysiological diseases.
    Cardiovascular research, 2001, Volume: 51, Issue:4

    Topics: Acute Kidney Injury; Animals; Arrhythmias, Cardiac; Ascites; Atrial Natriuretic Factor; Cardiovascul

2001
[New clinical laboratory tests for endocrine and metabolism disorders].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Nov-10, Volume: 90, Issue:11

    Topics: Adrenomedullin; Atrial Natriuretic Factor; Autoantibodies; Biomarkers; Bone Diseases, Metabolic; Dia

2001
Lysosomes and lysosomal enzymes in the heart.
    Frontiers of biology, 1975, Volume: 43, Issue:4

    Topics: Acid Phosphatase; Adrenal Cortex Hormones; Animals; Cardiomegaly; Cathepsins; Centrifugation, Densit

1975
[Collective review of endocrine factors in various types of cardio-circulatory insufficiency].
    Endocrinologia e scienza della costituzione, 1967, Volume: 29, Issue:2

    Topics: Adrenal Glands; Adrenal Medulla; Edema; Endocrine Glands; Heart; Heart Failure; Humans; Hyperaldoste

1967

Trials

10 trials available for thyroxine and Cardiac Failure

ArticleYear
The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial.
    The American journal of medicine, 2020, Volume: 133, Issue:7

    Topics: Aged; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Echocardiography; Female; Hea

2020
Effect of Short-Term L-Thyroxine Therapy on Left Ventricular Mechanics in Idiopathic Dilated Cardiomyopathy.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020, Volume: 33, Issue:10

    Topics: Cardiomyopathy, Dilated; Echocardiography; Heart Failure; Heart Ventricles; Humans; Infant, Newborn;

2020
    Journal of patient-reported outcomes, 2018, Volume: 2

    Topics: Adult; Aged; Animals; Astrocytes; Bariatric Surgery; Beta vulgaris; Bioreactors; Biotechnology; Bloo

2018
[Improvement in functional capacity after levothyroxine treatment in patients with chronic heart failure and subclinical hypothyroidism].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2013, Volume: 60, Issue:8

    Topics: Aged; Cardiovascular Agents; Comorbidity; Exercise Test; Female; Follow-Up Studies; Heart Failure; H

2013
[Therapeutic effect of low-dose thyroxin in elderly patients with refractory heart failure and euthyroid sick syndrome].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Chronic Disease; Drug Therapy, Combination; Euthyroid Sick Syndromes; Femal

2009
Effects of the thyromimetic agent diiodothyropropionic acid on body weight, body mass index, and serum lipoproteins: a pilot prospective, randomized, controlled study.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Aged; Body Mass Index; Body Weight; Chronic Disease; Diiodothyronines; Dose-Response Relationship, D

2010
[Efficacy and safety of hormone replacement therapy with levothyroxine in patients with subclinical hypothyroidism and heart failure].
    Kardiologiia, 2011, Volume: 51, Issue:5

    Topics: Administration, Oral; Aged; Biomarkers; Dose-Response Relationship, Drug; Drug Monitoring; Female; H

2011
Clinical effects of enhanced external counterpulsation treatment in patients with ischemic heart failure.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Volume: 12, Issue:3

    Topics: Aged; Blood Pressure; Cohort Studies; Counterpulsation; Electrocardiography; Female; Heart Failure;

2012
Effect of intravenous dopamine infusion on pituitary and thyroid function and on nephroprotection.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:3

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Dopamine; Female; Heart Failure; Humans; Infus

2012
Effects of thyroxine on cardiac function and lymphocyte beta-adrenoceptors in patients with chronic congestive heart failure.
    Chinese medical journal, 2003, Volume: 116, Issue:11

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Echocardiography; Female; Heart; Heart Failure; Heart

2003

Other Studies

92 other studies available for thyroxine and Cardiac Failure

ArticleYear
Effect of hypothyroidism on contractile performance of isolated end-stage failing human myocardium.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Calcium; Heart Failure; Humans; Hypothyroidism; Myocardial Contraction; Myocardium; Thyroxine

2022
Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways.
    Scientific reports, 2022, 08-27, Volume: 12, Issue:1

    Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Autophagy; Biphenyl Compounds; Cardiomega

2022
Thyroid Dysfunction and Cardiovascular Events in Patients With Dysglycemia.
    Canadian journal of diabetes, 2023, Volume: 47, Issue:3

    Topics: Heart Failure; Humans; Hyperthyroidism; Hypothyroidism; Risk Factors; Thyroid Diseases; Thyrotropin;

2023
Higher Peripheral Thyroid Sensitivity Is Linked to a Lower Risk of Heart Failure After Acute Myocardial Infarction.
    The Journal of clinical endocrinology and metabolism, 2023, 10-18, Volume: 108, Issue:11

    Topics: Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Thyr

2023
Clinical and Pathophysiologic Insights of Free triiodothyronine/Free thyroxine Ratio in Patients with Heart Failure with Preserved Ejection Fraction: Data from the NETDiamond Cohort.
    Cardiology, 2023, Volume: 148, Issue:3

    Topics: Aged; Female; Heart Failure; Humans; Male; Stroke Volume; Thyroxine; Triiodothyronine; Ventricular F

2023
Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism.
    Acta veterinaria Hungarica, 2023, 10-17, Volume: 71, Issue:2

    Topics: Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cat Diseases; Cats; Furosemide; Heart Failure;

2023
Circulating thyroid hormones and clinical parameters of heart failure in men.
    Scientific reports, 2023, Nov-20, Volume: 13, Issue:1

    Topics: Aged; Biomarkers; Cross-Sectional Studies; Heart Failure; Humans; Male; Natriuretic Peptide, Brain;

2023
Metabolic Dysfunction in Continuous-Flow Left Ventricular Assist Devices Patients and Outcomes.
    Journal of the American Heart Association, 2019, 11-19, Volume: 8, Issue:22

    Topics: Aged; Comorbidity; Diabetes Mellitus; Endocrine System Diseases; Euthyroid Sick Syndromes; Female; G

2019
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
    Journal of Korean medical science, 2020, Jun-08, Volume: 35, Issue:22

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Cholestasis; Drug Therapy, Combination; Heart

2020
Efficacy and safety of thyroxine therapy on patients with heart failure and subclinical hypothyroidism: A protocol for systematic review and meta-analysis.
    Medicine, 2021, Jan-22, Volume: 100, Issue:3

    Topics: Clinical Protocols; Heart Failure; Humans; Hypothyroidism; Meta-Analysis as Topic; Systematic Review

2021
Incidence and predictors of vasoplegia after heart failure surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2017, 03-01, Volume: 51, Issue:3

    Topics: Aged; Anemia; Cardiac Surgical Procedures; Female; Heart Failure; Heart Ventricles; Heart-Assist Dev

2017
Subclinical Hypothyroidism Is Associated With Adverse Prognosis in Heart Failure Patients.
    The Canadian journal of cardiology, 2018, Volume: 34, Issue:1

    Topics: Aged; Cardiac Catheterization; Cardiac Output, Low; Echocardiography; Exercise Test; Female; Heart F

2018
Inflammatory and neurohormonal modulation for congenital heart surgery: The quest continues.
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 156, Issue:3

    Topics: Dietary Supplements; Double-Blind Method; Heart Defects, Congenital; Heart Failure; Humans; Infant;

2018
Long-Term Outcome in Patients With Heart Failure Treated With Levothyroxine: An Observational Nationwide Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2019, 05-01, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Follow-Up Studies; Hear

2019
Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes.
    Circulation. Heart failure, 2018, Volume: 11, Issue:12

    Topics: Adult; Aged; Asymptomatic Diseases; Biomarkers; Comorbidity; Female; Heart Failure; Humans; Hypothyr

2018
Selenium deficiency and the dynamics of changes of thyroid profile in patients with acute myocardial infarction and chronic heart failure.
    Kardiologia polska, 2019, Aug-23, Volume: 77, Issue:7-8

    Topics: Aged; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Poland; Selenium; Thy

2019
Gene polymorphisms and thyroid function in patients with heart failure.
    Endocrine, 2014, Volume: 45, Issue:1

    Topics: Aged; Cohort Studies; Female; Genotype; Heart Failure; Humans; Male; Middle Aged; NF-kappa B p50 Sub

2014
Heart failure presenting as myxedema coma: case report and review article.
    Tennessee medicine : journal of the Tennessee Medical Association, 2013, Volume: 106, Issue:5

    Topics: Administration, Intravenous; Coma; Echocardiography; Electrocardiography; Female; Glucocorticoids; H

2013
Subclinical thyroid dysfunction and cardiac function amongst minority ethnic groups in the UK: a cross sectional study.
    International journal of cardiology, 2013, Oct-15, Volume: 168, Issue:6

    Topics: Aged; Asian People; Black People; Cross-Sectional Studies; Female; Heart Failure; Humans; Hyperthyro

2013
Antenatal management of recurrent fetal goitrous hyperthyroidism associated with fetal cardiac failure in a pregnant woman with persistent high levels of thyroid-stimulating hormone receptor antibody after ablative therapy.
    Endocrine journal, 2013, Volume: 60, Issue:12

    Topics: Ablation Techniques; Adult; Antithyroid Agents; Combined Modality Therapy; Dietary Supplements; Fema

2013
Thyroid hormone replacement therapy attenuates atrial remodeling and reduces atrial fibrillation inducibility in a rat myocardial infarction-heart failure model.
    Journal of cardiac failure, 2014, Volume: 20, Issue:12

    Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Electrocardiography; Female

2014
[Heart failure as early manifestation of neonatal hyperthyroidism. Case report].
    Revista chilena de pediatria, 2014, Volume: 85, Issue:2

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Fetal Growth Retardation; Heart Failure; Humans; Hy

2014
Long-term physiological T3 supplementation in hypertensive heart disease in rats.
    American journal of physiology. Heart and circulatory physiology, 2015, Sep-15, Volume: 309, Issue:6

    Topics: Animals; Collagen; Female; Heart; Heart Failure; Heart Ventricles; Hypertension; Hypothyroidism; Myo

2015
Age and thyroid hormone replacement delays the recovery from amiodarone-induced hypothyroidism.
    International journal of cardiology, 2016, Jan-01, Volume: 202

    Topics: Age Factors; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Failure; Hum

2016
Permanent atrial fibrillation in heart failure patients as another condition with increased reverse triiodothyronine concentration.
    Neuro endocrinology letters, 2016, Volume: 37, Issue:4

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Case-Control Studies; Cohort Studies; Female; Heart Fa

2016
Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients.
    Current pharmaceutical design, 2008, Volume: 14, Issue:26

    Topics: Aged; Chronic Disease; Disease Progression; Echocardiography; Electrocardiography; Female; Follow-Up

2008
Is pulverized levothyroxine a better therapeutic option in patients with heart failure?
    Southern medical journal, 2009, Volume: 102, Issue:8

    Topics: Administration, Oral; Aged; Female; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidi

2009
Decreasing brain natriuretic peptide levels after treatment for hyperthyroidism.
    Endocrine journal, 2009, Volume: 56, Issue:9

    Topics: Adult; Diagnostic Errors; Echocardiography, Doppler; Female; Heart Failure; Hemodynamics; Humans; Hy

2009
The oldest old subclinically hypothyroid subjects with pre-existing atrial fibrillation might not benefit from replacement therapy.
    Southern medical journal, 2010, Volume: 103, Issue:1

    Topics: Aged, 80 and over; Atrial Fibrillation; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyr

2010
Low triiodothyronine and exercise capacity in heart failure.
    International journal of cardiology, 2012, Jan-26, Volume: 154, Issue:2

    Topics: Aged; Biomarkers; Cardiac Output; Exercise; Exercise Test; Exercise Tolerance; Female; Heart Failure

2012
Myxoedematous pre-coma and heart failure.
    British journal of hospital medicine (London, England : 2005), 2011, Volume: 72, Issue:1

    Topics: Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Heart Failure; Humans; Hypo

2011
Effect of cardiac resynchronization therapy on thyroid function.
    Clinical cardiology, 2011, Volume: 34, Issue:11

    Topics: Adult; Aged; Biomarkers; Cardiac Resynchronization Therapy; Female; Heart Failure; Humans; Male; Mid

2011
Incidence and prevalence of hypothyroidism in patients affected by chronic heart failure: role of amiodarone.
    Endocrine, metabolic & immune disorders drug targets, 2012, Volume: 12, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Cohort Studies; Female; Follow-Up Studies

2012
Panhypopituitarism presenting as life-threatening heart failure caused by an inherited microdeletion in 1q25 including LHX4.
    Pediatrics, 2012, Volume: 129, Issue:2

    Topics: Alleles; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Drug Therapy, Comb

2012
Thyroid function and the risk of coronary heart disease: 12-year follow-up of the HUNT study in Norway.
    Clinical endocrinology, 2012, Volume: 77, Issue:6

    Topics: Aged; Coronary Disease; Female; Heart Failure; Hospitalization; Humans; Hypothyroidism; Male; Middle

2012
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts.
    Circulation, 2012, Aug-28, Volume: 126, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Female; Follow-Up Studies; Heart Failure; Humans; Hypot

2012
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts.
    Circulation, 2012, Aug-28, Volume: 126, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Female; Follow-Up Studies; Heart Failure; Humans; Hypot

2012
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts.
    Circulation, 2012, Aug-28, Volume: 126, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Female; Follow-Up Studies; Heart Failure; Humans; Hypot

2012
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts.
    Circulation, 2012, Aug-28, Volume: 126, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Female; Follow-Up Studies; Heart Failure; Humans; Hypot

2012
[Changes and clinical significance of serum thyroxine level in patients with congestive heart failure].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1999, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Heart Failure; Humans; Male; Middle Aged; Thyrox

1999
[Changes of thyroid hormone levels in the progression of coronary arteriosclerosis].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:4

    Topics: Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Disease Progression; Heart Fail

2004
[Study on relationship among thyroid hormone relativity and Syndrome Differentiation-types of TCM in patients with congestive heart failure].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:10

    Topics: Adult; Aged; Atrial Natriuretic Factor; Diagnosis, Differential; Female; Heart Failure; Humans; Male

2004
Serum-free thyroxine and thyrotropin concentrations in euthyroid patients with decompensated congestive heart failure.
    International journal of cardiology, 2005, Jul-10, Volume: 102, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Echocardiography; Female; Heart Failure; Humans; Male; M

2005
[Prolactin (PRL), thyrotropin (TSH), free thyroid hormones (fT4), (fT3) and testosterone (TTE) level in men with chronic heart failure].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 113, Issue:4

    Topics: Adult; Aged; Biomarkers; Fluorescent Antibody Technique; Heart Failure; Humans; Male; Middle Aged; P

2005
[Incidence and predictors of thyroid dysfunction caused by long-term intake of amiodaron].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:10

    Topics: Age Factors; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Failure; Humans; Hypothyroidism; Inci

2005
[Association between free thyroxin concentration and degree of heart failure in patients with chronic heart insufficiency].
    Casopis lekaru ceskych, 2005, Volume: 144, Issue:11

    Topics: Chronic Disease; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Thyro

2005
Thyroid abnormalities in infantile hepatic hemangioendothelioma.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:7

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies;

2007
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study.
    Langenbeck's archives of surgery, 2007, Volume: 392, Issue:6

    Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B

2007
[Hypocalcemic cardiomyopathy secondary to hypoparathyroidism after a thyroidectomy: report of one case].
    Revista medica de Chile, 2007, Volume: 135, Issue:3

    Topics: Adult; Calcium; Chronic Disease; Diagnosis, Differential; Female; Heart Failure; Humans; Hypocalcemi

2007
Even mild changes in free thyroxine could influence the degree of heart failure measured by its biological surrogates.
    Physiological research, 2008, Volume: 57, Issue:4

    Topics: Aged; Chronic Disease; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain;

2008
Post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure: the role of cytokines.
    Cytokine, 2008, Volume: 41, Issue:2

    Topics: Cytokines; Female; Heart Failure; Hormone Replacement Therapy; Humans; Hypothyroidism; Interleukin-6

2008
[Surgical indications, preoperative care, surgery and postoperative care in Basedow's disease and other forms of hyperthyroidism].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1980, Volume: 51, Issue:10

    Topics: Adenoma; Adrenergic beta-Antagonists; Adult; Aged; Carbimazole; Graves Disease; Heart Failure; Human

1980
Cardiac alterations at the myofibrillar level: is a redistribution of the myosin isoenzyme pattern decisive for cardiac failure in haemodynamic overload?
    European heart journal, 1984, Volume: 5 Suppl F

    Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart Failure; Hemody

1984
[Relation between thyroid hormone concentration of the blood and the blood collection site and circulatory status].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1983, Oct-15, Volume: 36, Issue:20

    Topics: Adult; Aorta; Coronary Vessels; Female; Forearm; Heart Failure; Humans; Male; Middle Aged; Pulmonary

1983
[The changes in the serum thyroid hormone concentrations in Graves patients with congestive heart failure the onset of T4 toxicosis (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1982, Mar-10, Volume: 71, Issue:3

    Topics: Adult; Aged; Female; Graves Disease; Heart Failure; Humans; Male; Middle Aged; Thyroid Hormones; Thy

1982
Cautionary tales from general practice.
    Australian family physician, 1982, Volume: 11, Issue:1

    Topics: Aged; Angina Pectoris; Diagnostic Errors; Female; Heart Failure; Humans; Hypothyroidism; Thyroxine

1982
Congestive heart failure due to reversible cardiomyopathy in patients with hyperthyroidism.
    The American journal of the medical sciences, 1995, Volume: 310, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cardiomyopathy, Dilated; Echocardiography; Female; Heart Failure; Hu

1995
Cardiac toxicity in an adolescent following chronic lithium and imipramine therapy.
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 1993, Volume: 14, Issue:5

    Topics: Adolescent; Cardiac Complexes, Premature; Cardiomyopathies; Child; Child Behavior Disorders; Drug Th

1993
Thyroid function in dogs with spontaneous and induced congestive heart failure.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1994, Volume: 58, Issue:3

    Topics: Animals; Dog Diseases; Dogs; Female; Heart Failure; Male; Thyroid Gland; Thyrotropin; Thyroxine; Tri

1994
Hypothyroidism in an elderly patient with congestive heart disease.
    Maryland medical journal (Baltimore, Md. : 1985), 1994, Volume: 43, Issue:9

    Topics: Aged; Female; Heart Failure; Humans; Hypothyroidism; Thyroxine

1994
Thyrotoxicosis-induced congestive heart failure in an urban hospital.
    The American journal of the medical sciences, 1994, Volume: 308, Issue:6

    Topics: Adult; Atrial Fibrillation; Female; Heart Failure; Hemodynamics; Hospitals, Urban; Humans; Male; Mid

1994
[Serum thyroid hormone levels correlate with cardiac function and ventricular tachyarrhythmia in patients with chronic heart failure].
    Journal of cardiology, 1993, Volume: 23, Issue:2

    Topics: Echocardiography; Female; Heart; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Tachycardia,

1993
Participation of the pituitary-thyroid axis in the cardiovascular system in elderly patients with congestive heart failure.
    Journal of medicine, 1997, Volume: 28, Issue:1-2

    Topics: Aged; Atrial Natriuretic Factor; Cardiovascular System; Euthyroid Sick Syndromes; Female; Heart Fail

1997
Intravenous thyroid hormone supplementation in heart failure with cardiogenic shock.
    Journal of cardiac failure, 1999, Volume: 5, Issue:1

    Topics: Adult; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Intr

1999
The effect of chronic mechanical circulatory support on neuroendocrine activation in patients with end-stage heart failure.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 16, Issue:1

    Topics: Adult; Catecholamines; Heart Failure; Heart-Assist Devices; Humans; Hydrocortisone; Middle Aged; Neu

1999
[Effect of ginseng injection in treating congestive heart failure and its influence on thyroid hormones].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1999, Volume: 19, Issue:4

    Topics: Adult; Aged; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Infusions, Intravenous; Male; Mid

1999
Managing patients with acute thyrotoxicosis.
    Critical care nurse, 2002, Volume: 22, Issue:1

    Topics: Acute Disease; Administration, Oral; Adult; Antithyroid Agents; Female; Heart Failure; Humans; Potas

2002
Antenatal diagnosis and treatment of a case of fetal goitrous hypothyroidism associated with high-output cardiac failure.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2002, Volume: 19, Issue:5

    Topics: Adult; Congenital Hypothyroidism; Female; Fetal Diseases; Follow-Up Studies; Goiter; Heart Failure;

2002
Heart failure accompanied by sick euthyroid syndrome and exercise training.
    Current opinion in cardiology, 2002, Volume: 17, Issue:3

    Topics: Aged; Atrial Function, Left; Euthyroid Sick Syndromes; Exercise Test; Exercise Therapy; Female; Hear

2002
Diagnosis of hyperthyroidism when serum-thyroxine alone is raised.
    Lancet (London, England), 1977, Jul-09, Volume: 2, Issue:8028

    Topics: Adult; Aged; Delirium; False Negative Reactions; Female; Follow-Up Studies; Gastroenteritis; Graves

1977
Aldosterone in myxoedema.
    Lancet (London, England), 1978, Dec-16, Volume: 2, Issue:8103

    Topics: Aldosterone; Dose-Response Relationship, Drug; Heart Failure; Humans; Hyperaldosteronism; Myxedema;

1978
Thyroxine-replacement therapy, aldosterone, and cardiac failure.
    Lancet (London, England), 1979, Feb-17, Volume: 1, Issue:8112

    Topics: Aldosterone; Heart Failure; Hormones; Humans; Hypothyroidism; Thyroxine

1979
Occult thyrotoxicosis: a correctable cause of "idiopathic" atrial fibrillation.
    The American journal of cardiology, 1979, Volume: 44, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Carbimazole; Female; Heart Failure; Humans; Hyperthyroidi

1979
Neonatal thyrotoxicosis associated with the hyperviscosity syndrome.
    The Journal of pediatrics, 1977, Volume: 90, Issue:2

    Topics: Blood Viscosity; Exchange Transfusion, Whole Blood; Heart Failure; Hematocrit; Humans; Hyperthyroidi

1977
Causes of high free-thyroxine index values in sick euthyroid elderly patients.
    Age and ageing, 1976, Volume: 5, Issue:4

    Topics: Atrial Fibrillation; Digitalis Glycosides; Disease; Diuretics; Drug-Related Side Effects and Adverse

1976
[Minimal cardiac transit time in thyroid disorders and in the effort syndrome].
    Nuclear-Medizin, 1975, Mar-31, Volume: 14, Issue:1

    Topics: Adult; Blood Flow Velocity; Cardiomyopathies; Diagnosis, Differential; Female; Heart; Heart Failure;

1975
Congestive cardiomyopathy in hypothyroidism.
    The Western journal of medicine, 1975, Volume: 123, Issue:3

    Topics: Adult; Diagnosis, Differential; Female; Heart; Heart Failure; Humans; Hypothyroidism; Thyroxine

1975
Plasma free fatty acids, inhibitor of extrathyroidal conversion of T4 to T3 and thyroid hormone binding inhibitor in patients with various nonthyroidal illnesses.
    Endocrinologia japonica, 1992, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Binding, Competitive; Carrier Proteins; Diabetes Mell

1992
Preliminary evaluation of a fluorescence polarization immunoassay (Abbott TDx) for estimating serum free thyroxine concentrations in patients with critical nonthyroid illness and low total thyroxine concentrations in serum.
    Clinical chemistry, 1992, Volume: 38, Issue:9

    Topics: Evaluation Studies as Topic; Fluorescence Polarization; Heart Failure; Humans; Immunoassay; Infectio

1992
The real magic.
    Postgraduate medicine, 1992, Volume: 91, Issue:8

    Topics: Adult; Cardiomegaly; Heart Failure; Humans; Hypothyroidism; Male; Thyroxine

1992
Excess synthroid ingestion presenting as congestive heart failure.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:1

    Topics: Adult; Female; Heart Failure; Humans; Male; Thyrotoxicosis; Thyroxine

1992
[Hypothyroid cardiomyopathy--an underdiagnosed cause of heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990, Jun-10, Volume: 110, Issue:15

    Topics: Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female; Heart Failure; Heart Sep

1990
[Subcellular basis of disorders of the contractile capacity of the heart in L-thyroxine-induced thyrotoxicosis].
    Kardiologiia, 1990, Volume: 30, Issue:2

    Topics: Animals; Disease Models, Animal; Dogs; Heart Failure; Male; Myocardial Contraction; Myocardium; Sarc

1990
Diagnosis and management of hyperthyroidism.
    The Medical journal of Australia, 1986, Sep-15, Volume: 145, Issue:6

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Female; Heart Failure; Humans; Hyperthyroidism; Inf

1986
Myocardial infarction: severe reversible ischemia and shock following excess thyroid administration in a man with normal coronary arteries.
    Archives of internal medicine, 1989, Volume: 149, Issue:3

    Topics: Adult; Heart Failure; Humans; Male; Self Medication; Thyroxine

1989
Primary hypothyroidism in severe chronic heart failure.
    Japanese journal of medicine, 1988, Volume: 27, Issue:1

    Topics: Adult; Aged; Cardiomegaly; Euthyroid Sick Syndromes; Female; Heart Failure; Heart Function Tests; Hu

1988
Effects of L-thyroxine in rats with chronic heart failure after myocardial infarction.
    The American journal of physiology, 1987, Volume: 253, Issue:2 Pt 2

    Topics: Animals; Chronic Disease; Heart Failure; Isoenzymes; Myocardial Infarction; Myosins; Rats; Rats, Inb

1987
Effect of oral frusemide on diagnostic indices of thyroid function.
    Clinical endocrinology, 1987, Volume: 26, Issue:4

    Topics: Administration, Oral; Furosemide; Heart Failure; Humans; Thyroid Function Tests; Thyroid Gland; Thyr

1987
[A 58-year-old type-II diabetic patient with severe insulin resistance].
    Wiener klinische Wochenschrift, 1987, Sep-11, Volume: 99, Issue:17

    Topics: Autoantibodies; Breast Neoplasms; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Insulin

1987
[The determination of the "free thyroxine" index in internal diseases].
    Nuclear-Medizin, 1967, Jul-15, Volume: 6, Issue:2

    Topics: Diagnosis, Differential; Erythrocytes; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Hypot

1967
The series elasticity of cardiac muscle in hyperthyroidism, ventricular hypertrophy, and heart failure.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:2

    Topics: Animals; Cardiomegaly; Cats; Elasticity; Heart; Heart Failure; Heart Ventricles; Hyperthyroidism; Mu

1968
Analysis of myocardial mucopolysaccharides in hyper-and hypothyroid rats and guinea-pigs.
    Annales medicinae experimentalis et biologiae Fenniae, 1970, Volume: 48, Issue:1

    Topics: Animals; Aorta; Chondroitin; Electrophoresis; Glycosaminoglycans; Guinea Pigs; Heart Failure; Hepari

1970
Letter: Serum digoxin and thyroid hormones.
    Annals of internal medicine, 1974, Volume: 81, Issue:1

    Topics: Digoxin; Heart Failure; Humans; Iodine Radioisotopes; Male; Radioimmunoassay; Thyroxine; Triiodothyr

1974
Estimation of rapidly exchangeable cellular thyroxine from the plasma disappearance curves of simultaneously administered thyroxine-131-I and albumin-125-I.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:5

    Topics: Heart Failure; Humans; Iodine Isotopes; Liver; Liver Diseases; Radioisotope Dilution Technique; Seru

1967
Glucagon and the failing heart.
    Annals of internal medicine, 1970, Volume: 73, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cats; Dogs; Glucagon; Heart Failure; Humans; Thyroxine

1970