thyroxine has been researched along with Carcinoma, Neuroendocrine in 3 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Carcinoma, Neuroendocrine: A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round blue cells, granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small (oat) cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Upon initiating treatment with selpercatinib, athyreotic patients developed clinical hypothyroidism with approximately 60% lower T3 levels despite adequate levothyroxine supplementation, whereas in patients with NSCLC, who retain a normal thyroid, selpercatinib resulted in a more attenuated reduction in serum T3, which was dose-dependent." | 4.12 | Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase. ( Bianco, AC; Boucai, L; Drilon, A; Fagin, JA; Krishnamoorthy, GP; Rudin, CM; Salas-Lucia, F; Sherman, E, 2022) |
| "Medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) are two different types of thyroid carcinoma." | 1.72 | Co-existence of Papillary and Medullary Thyroid Carcinoma: Reports of Three Cases. ( Calapkulu, M; Cander, S; Ersoy, C; Erturk, E; Gul, OO; Sagiroglu, MF; Saraydaroglu, O, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Boucai, L | 1 |
| Salas-Lucia, F | 1 |
| Krishnamoorthy, GP | 1 |
| Sherman, E | 1 |
| Rudin, CM | 1 |
| Drilon, A | 1 |
| Bianco, AC | 1 |
| Fagin, JA | 1 |
| Calapkulu, M | 1 |
| Gul, OO | 1 |
| Cander, S | 1 |
| Sagiroglu, MF | 1 |
| Saraydaroglu, O | 1 |
| Erturk, E | 1 |
| Ersoy, C | 1 |
| Tomoda, C | 1 |
| Miyauchi, A | 1 |
3 other studies available for thyroxine and Carcinoma, Neuroendocrine
| Article | Year |
|---|---|
Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase.
Topics: Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Humans; Hypothyroidism; Iodide Peroxidase | 2022 |
Co-existence of Papillary and Medullary Thyroid Carcinoma: Reports of Three Cases.
Topics: Carcinoma, Neuroendocrine; Carcinoma, Papillary; Humans; Iodine Radioisotopes; Thyroid Cancer, Papil | 2022 |
Undetectable serum thyroglobulin levels in patients with medullary thyroid carcinoma after total thyroidectomy without radioiodine ablation.
Topics: Adult; Aged; Carcinoma; Carcinoma, Neuroendocrine; Carcinoma, Papillary; Female; Humans; Male; Middl | 2012 |