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thyroxine and Carcinoma, Medullary

thyroxine has been researched along with Carcinoma, Medullary in 14 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
"Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib."6.71Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005)
"Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib."2.71Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005)
"Primary therapy of thyroid cancer is an adequate surgery: total thyreoidectomy and, if necessary, lymph node dissection or limited surgery in selected cases."2.47[Differentiated thyroid cancer -- 2009]. ( Konrády, A, 2011)
"Differentiated thyroid cancer is increasing in prevalence."2.46Postoperative management of differentiated thyroid cancer. ( Kim, M; Sabet, A, 2010)
"Differentiated thyroid carcinoma is the most common pediatric endocrine tumor, constituting 0."2.44Thyroid nodules and cancers in children. ( Josefson, J; Zimmerman, D, 2008)
"Papillary and follicular thyroid cancer in childhood and adolescence is more advanced upon presentation than in adults, as evident from a higher frequency of extra-thyroidal spread."2.41Thyroid cancer in children and adolescents--consequences in later life. ( Wiersinga, WM, 2001)
"Pseudohypoparathyroidism Ia (PHP Ia) is characterized by resistance to PTH and many other stimuli because of deficiency of stimulatory G protein alpha-subunit."1.31Pseudohypoparathyroidism Ia and hypercalcitoninemia. ( Bauters, C; D'herbomez, M; Decoulx, M; Fayard, A; Pigny, P; Vlaeminck-Guillem, V; Wémeau, JL, 2001)
"In 3 patients papillary thyroid cancer was associated with chronic lymphocytic thyroiditis."1.30Thyroid carcinoma in children and adolescents. ( Andreoli, M; Danese, D; Farsetti, A; Gardini, A; Pontecorvi, A; Sciacchitano, S, 1997)
" Despite this encouraging results thyroxine substitution therapy in the follow-up carries some problems concerning optimal dosage and non-compliance."1.30Results and follow-up in eleven MEN 2A gene carriers after prophylactic thyroidectomy. ( Buhr, H; Frank-Raue, K; Herfarth, C; Höppner, W; Raue, F, 1997)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's6 (42.86)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Josefson, J1
Zimmerman, D1
Brenta, G1
Celi, FS1
Pisarev, M1
Schnitman, M1
Sinay, I1
Arias, P1
Yalcin, M1
Dyskin, E1
Lansing, L1
Bharali, DJ1
Mousa, SS1
Bridoux, A1
Hercbergs, AH1
Lin, HY1
Davis, FB1
Glinsky, GV1
Glinskii, A1
Ma, J1
Davis, PJ1
Mousa, SA1
Sabet, A1
Kim, M1
Konrády, A1
Pacini, F1
Castagna, MG1
Brilli, L1
Pentheroudakis, G1
de Groot, JW1
Zonnenberg, BA1
Plukker, JT1
van Der Graaf, WT1
Links, TP1
Marks, SL1
Koblik, PD1
Hornof, WJ1
Feldman, EC1
Danese, D1
Gardini, A1
Farsetti, A1
Sciacchitano, S1
Andreoli, M1
Pontecorvi, A1
Frank-Raue, K1
Höppner, W1
Buhr, H1
Herfarth, C1
Raue, F1
Wells, SA1
Skinner, MA1
Hahm, JR1
Lee, MS1
Min, YK1
Lee, MK1
Kim, KW1
Nam, SJ1
Yang, JH1
Chung, JH1
Vlaeminck-Guillem, V1
D'herbomez, M1
Pigny, P1
Fayard, A1
Bauters, C1
Decoulx, M1
Wémeau, JL1
Wiersinga, WM1

Reviews

4 reviews available for thyroxine and Carcinoma, Medullary

ArticleYear
Thyroid nodules and cancers in children.
    Pediatric endocrinology reviews : PER, 2008, Volume: 6, Issue:1

    Topics: Carcinoma, Medullary; Carcinoma, Papillary, Follicular; Child; Disease Susceptibility; Follow-Up Stu

2008
Postoperative management of differentiated thyroid cancer.
    Otolaryngologic clinics of North America, 2010, Volume: 43, Issue:2

    Topics: Adenocarcinoma, Papillary; Carcinoma, Medullary; Combined Modality Therapy; Follow-Up Studies; Human

2010
[Differentiated thyroid cancer -- 2009].
    Orvosi hetilap, 2011, Jan-30, Volume: 152, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Carcinoma; Carcinoma, Medullary

2011
Thyroid cancer in children and adolescents--consequences in later life.
    Journal of pediatric endocrinology & metabolism : JPEM, 2001, Volume: 14 Suppl 5

    Topics: Adolescent; Adult; Carcinoma, Medullary; Carcinoma, Papillary, Follicular; Child, Preschool; Humans;

2001

Trials

1 trial available for thyroxine and Carcinoma, Medullary

ArticleYear
Imatinib induces hypothyroidism in patients receiving levothyroxine.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Carcinoma, Medullary; Drug Synergism; Female; Gastro

2005

Other Studies

9 other studies available for thyroxine and Carcinoma, Medullary

ArticleYear
Acute thyroid hormone withdrawal in athyreotic patients results in a state of insulin resistance.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:6

    Topics: Acute Disease; Adult; Aged; Carcinoma, Medullary; Carcinoma, Papillary; Female; Glucose Tolerance Te

2009
Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:4

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Medullary; Cells, Cultured; Chick Embryo; Ch

2010
Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 7

    Topics: Antineoplastic Agents; Carcinoma, Medullary; Carcinoma, Papillary; Combined Modality Therapy; Humans

2012
99mTc-pertechnetate imaging of thyroid tumors in dogs: 29 cases (1980-1992).
    Journal of the American Veterinary Medical Association, 1994, Mar-01, Volume: 204, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Medullary; Dog Diseases; Dogs; Female; Lung

1994
Thyroid carcinoma in children and adolescents.
    European journal of pediatrics, 1997, Volume: 156, Issue:3

    Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Adolescent; Carcinoma, Medullary; Child; Comb

1997
Results and follow-up in eleven MEN 2A gene carriers after prophylactic thyroidectomy.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1997, Volume: 105 Suppl 4

    Topics: Adolescent; Carcinoma, Medullary; Child; Child, Preschool; Female; Heterozygote; Humans; Male; Multi

1997
Prophylactic thyroidectomy, based on direct genetic testing, in patients at risk for the multiple endocrine neoplasia type 2 syndromes.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1998, Volume: 106, Issue:1

    Topics: Adolescent; Adult; Calcitonin; Calcitriol; Calcium; Calcium Gluconate; Carcinoma, Medullary; Catecho

1998
Routine measurement of serum calcitonin is useful for early detection of medullary thyroid carcinoma in patients with nodular thyroid diseases.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Biopsy, Needle; Calcitonin; Carcinoma, M

2001
Pseudohypoparathyroidism Ia and hypercalcitoninemia.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:7

    Topics: Adult; Calcitonin; Carcinoma, Medullary; Cyclic AMP; Drosophila Proteins; Female; GTP-Binding Protei

2001