thyroxine has been researched along with Cancer of Prostate in 16 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Blood samples from 140 patients with prostate cancer were analyzed preoperatively and stratified according to postoperative histopathological differentiation." | 1.56 | Association of Triiodothyronine Levels With Prostate Cancer Histopathological Differentiation and Tumor Stage. ( Butković, MB; Franceschi, M; Fröbe, A; Jakovčević, D; Jukić, T; Krilić, D; Krušlin, B; Mažuran, B; Milošević, M; Murgić, J; Ovčariček, PP; Ovčariček, S; Ružić, B; Šoipi, Š; Verburg, FA, 2020) |
| "In vitro, in the LNCaP prostate cancer cell line, we found that both T3 and T4 increased the number of viable cells (Trypan blue assay), and only T4 response was fully blocked in the presence of an integrin-binding inhibitor peptide (RGD, arginine-glycine-aspartate)." | 1.56 | A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. ( Aceves, C; Álvarez, L; Anguiano, B; Delgado-González, E; Montes de Oca, C; Ortiz, Z; Rodríguez-Castelán, J; Sánchez-Tusie, A; Zarco, C, 2020) |
| "Associations with cancer-related deaths were also explored." | 1.46 | Higher thyrotropin concentration is associated with increased incidence of colorectal cancer in older men. ( Alfonso, H; Chan, YX; Chubb, SA; Fegan, PG; Flicker, L; Golledge, J; Hankey, GJ; Yeap, BB, 2017) |
| "Prostate cancer is one of the most common malignancies in adult males and metastasis is the leading cause of death cases without satisfactory treatment options." | 1.43 | Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway. ( Chen, L; Li, X; Song, Y; Sun, Y; Xiao, Y; Xing, Y; Zhang, P, 2016) |
| "This mild hypothyroidism was detected in two of the 96 patients of the control group (2." | 1.33 | Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer. ( Catalán, R; Cecchini, L; Esquena, S; Morote, J; Orsola, A; Planas, J; Raventós, CX; Reventós, J; Salvador, C; Trilla, E, 2005) |
| "Patients with prostate cancer demonstrate a significant change in thyroid hormones when treated with estrogens after orchiectomy." | 1.26 | [Thyroid hormones in metastasizing prostate cancer treated with polyestradiol phosphate]. ( Dunzendorfer, U; Schulz, H, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ovčariček, PP | 1 |
| Fröbe, A | 1 |
| Verburg, FA | 1 |
| Murgić, J | 1 |
| Butković, MB | 1 |
| Ovčariček, S | 1 |
| Mažuran, B | 1 |
| Krušlin, B | 1 |
| Jakovčević, D | 1 |
| Šoipi, Š | 1 |
| Ružić, B | 1 |
| Milošević, M | 1 |
| Krilić, D | 1 |
| Franceschi, M | 1 |
| Jukić, T | 1 |
| Sánchez-Tusie, A | 1 |
| Montes de Oca, C | 1 |
| Rodríguez-Castelán, J | 1 |
| Delgado-González, E | 1 |
| Ortiz, Z | 1 |
| Álvarez, L | 1 |
| Zarco, C | 1 |
| Aceves, C | 1 |
| Anguiano, B | 1 |
| Zhang, P | 1 |
| Chen, L | 1 |
| Song, Y | 1 |
| Li, X | 1 |
| Sun, Y | 1 |
| Xiao, Y | 1 |
| Xing, Y | 1 |
| Khan, SR | 1 |
| Chaker, L | 1 |
| Ruiter, R | 1 |
| Aerts, JG | 1 |
| Hofman, A | 1 |
| Dehghan, A | 1 |
| Franco, OH | 1 |
| Stricker, BH | 1 |
| Peeters, RP | 1 |
| Chan, YX | 1 |
| Alfonso, H | 1 |
| Chubb, SA | 1 |
| Fegan, PG | 1 |
| Hankey, GJ | 1 |
| Golledge, J | 1 |
| Flicker, L | 1 |
| Yeap, BB | 1 |
| Mondul, AM | 1 |
| Weinstein, SJ | 1 |
| Bosworth, T | 1 |
| Remaley, AT | 1 |
| Virtamo, J | 1 |
| Albanes, D | 1 |
| Salminen, E | 1 |
| Koskinen, A | 1 |
| Backman, H | 1 |
| Nurmi, M | 1 |
| Morote, J | 1 |
| Esquena, S | 1 |
| Orsola, A | 1 |
| Salvador, C | 1 |
| Trilla, E | 1 |
| Cecchini, L | 1 |
| Raventós, CX | 1 |
| Planas, J | 1 |
| Catalán, R | 1 |
| Reventós, J | 1 |
| Dunzendorfer, U | 1 |
| Schulz, H | 1 |
| Valenti, G | 2 |
| Banchini, A | 2 |
| Denti, L | 1 |
| Zavaroni, D | 2 |
| Zaninovich, AA | 2 |
| Vescovi, PP | 1 |
| Ponticelli, P | 1 |
| Hafez, ES | 1 |
| Dutkiewicz, S | 1 |
| Witeska, A | 1 |
| Nauman, A | 1 |
| Barreca, T | 1 |
| Martorana, G | 1 |
| Franceschini, R | 1 |
| Giberti, C | 1 |
| Brancadoro, MT | 1 |
| Messina, V | 1 |
| Rolandi, E | 1 |
| Socolow, EL | 1 |
| Woeber, KA | 1 |
| Purdy, RH | 1 |
| Holloway, MT | 1 |
| Ingbar, SH | 1 |
1 review available for thyroxine and Cancer of Prostate
| Article | Year |
|---|---|
Direct and indirect effects of estrogens on thyroidal economy of man.
Topics: Estradiol; Estrogens; Humans; Iodine; Male; Prostatic Neoplasms; Protein Binding; Thyroid Diseases; | 1981 |
1 trial available for thyroxine and Cancer of Prostate
| Article | Year |
|---|---|
Circulating thyroxine, thyroid-stimulating hormone, and hypothyroid status and the risk of prostate cancer.
Topics: Aged; alpha-Tocopherol; beta Carotene; Case-Control Studies; Genetic Association Studies; Humans; Hy | 2012 |
14 other studies available for thyroxine and Cancer of Prostate
| Article | Year |
|---|---|
Association of Triiodothyronine Levels With Prostate Cancer Histopathological Differentiation and Tumor Stage.
Topics: Aged; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Preoperative Period; Prospectiv | 2020 |
A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model.
Topics: Adenocarcinoma; Animals; Apoptosis; Body Weight; Cell Proliferation; Disease Models, Animal; Male; M | 2020 |
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Topics: Anoikis; Apoptosis; Cell Line, Tumor; Cell Movement; Gene Silencing; Humans; Male; MAP Kinase Signal | 2016 |
Thyroid Function and Cancer Risk: The Rotterdam Study.
Topics: Aged; Breast Neoplasms; Female; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Lung Neoplasm | 2016 |
Higher thyrotropin concentration is associated with increased incidence of colorectal cancer in older men.
Topics: Age Factors; Aged; Colorectal Neoplasms; Female; Humans; Incidence; Lung Neoplasms; Male; Neoplasms; | 2017 |
Effect of adjuvant androgen deprivation on thyroid function tests in prostate cancer patients.
Topics: Aged; Androgen Antagonists; Chemotherapy, Adjuvant; Estradiol; Humans; Male; Middle Aged; Prospectiv | 2004 |
Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Cross-Sectional Studies; Gonadotropin-Relea | 2005 |
[Thyroid hormones in metastasizing prostate cancer treated with polyestradiol phosphate].
Topics: Aged; Bone Neoplasms; Estradiol; Estradiol Congeners; Humans; Male; Middle Aged; Prostatic Hyperplas | 1982 |
Acute infusion of hCG and thyroid hormone pattern before and after bilateral orchiectomy.
Topics: Aged; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hu | 1984 |
Pituitary-thyroid axis after bilateral orchiectomy in men.
Topics: Aged; Castration; Humans; Kinetics; Male; Middle Aged; Pituitary Gland; Prostatic Neoplasms; Thyroid | 1982 |
The deiodination of thyroxine to triiodothyronine in the testes of patients with prostate cancer.
Topics: Aged; Aged, 80 and over; Diethylstilbestrol; Humans; Iodide Peroxidase; Male; Middle Aged; Orchiecto | 1995 |
Suppression of testicular androgenesis by D-tryptophan-6-luteinizing hormone-releasing hormone does not affect TSH secretion in male subjects.
Topics: Aged; Androgen Antagonists; Androgens; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Pr | 1986 |
Thyroxine kinetics during prolonged estrogen administration.
Topics: Aged; Alkadienes; Diethylstilbestrol; Estrogens; Humans; Iodine Radioisotopes; Kinetics; Male; Middl | 1973 |
Preparation of I-131-labeled human serum prealbumin and its metabolism in normal and sick patients.
Topics: Adult; Aged; Autoradiography; Blood; Blood Protein Electrophoresis; Chromatography, Paper; Female; H | 1965 |