thyroxine has been researched along with Brain Ischemia in 22 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum triiodothyronine (T3) concentration was reported to be associated with the prognosis after acute ischemic stroke." | 3.91 | The prognostic value of total T3 after acute cerebral infarction is age-dependent: a retrospective study on 768 patients. ( Hu, XY; Li, LQ; Li, WY; Lv, W; Xu, XY, 2019) |
| " In a previous investigation, post-resuscitation infusion of levothyroxine sodium (L-T4) to normalize serum 3,5,3'-triiodothyronine (T3) concentrations was associated with significant reduction of neurologic deficit caused by severe global cerebral ischemia." | 3.69 | Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs. ( D'Alecy, LG; Mayor, GH; Nachreiner, RF; Whitesall, SE; Zwemer, CF, 1996) |
| " This risk was increased in those who took a higher dosage of levothyroxine (HR: 1." | 1.51 | Increased cardiovascular risk in thyroid cancer patients taking levothyroxine: a nationwide cohort study in Korea. ( Cho, B; Guallar, E; Lim, H; Park, JH; Park, Y; Shin, DW; Song, SO; Suh, B; Yun, JM, 2019) |
| "Cerebral ischemia was induced by middle cerebral artery occlusion in male Wistar rats." | 1.46 | Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke. ( Akbari, M; Hassanzadeh, G; Kashani, IR; Mortezaee, K; Sabbaghziarani, F; Soleimani, M; Zendedel, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Br, A | 1 |
| Chandra, BJS | 1 |
| Chen, Z | 1 |
| Sun, Y | 1 |
| Zhang, Y | 1 |
| He, Y | 1 |
| Chen, H | 1 |
| Su, Y | 1 |
| Jiang, X | 1 |
| Xing, H | 1 |
| Wu, J | 1 |
| Du, R | 1 |
| Liu, H | 1 |
| Chen, J | 1 |
| Wang, J | 1 |
| Wang, C | 1 |
| Wu, Y | 1 |
| Ambrosius, W | 1 |
| Rosinska, J | 1 |
| Michalak, S | 1 |
| Lukasik, M | 1 |
| Kazmierski, R | 1 |
| Kozubski, W | 1 |
| Suh, B | 1 |
| Shin, DW | 1 |
| Park, Y | 1 |
| Lim, H | 1 |
| Yun, JM | 1 |
| Song, SO | 1 |
| Park, JH | 1 |
| Cho, B | 1 |
| Guallar, E | 1 |
| Li, LQ | 1 |
| Xu, XY | 1 |
| Li, WY | 1 |
| Hu, XY | 1 |
| Lv, W | 1 |
| Forti, P | 1 |
| Maioli, F | 1 |
| Coveri, M | 1 |
| Nativio, V | 1 |
| Arnone, G | 1 |
| Loreti, A | 1 |
| Zoli, M | 1 |
| Sacquegna, T | 1 |
| Procaccianti, G | 1 |
| Suda, S | 1 |
| Muraga, K | 1 |
| Kanamaru, T | 1 |
| Okubo, S | 1 |
| Abe, A | 1 |
| Aoki, J | 1 |
| Suzuki, K | 1 |
| Sakamoto, Y | 1 |
| Shimoyama, T | 1 |
| Nito, C | 1 |
| Kimura, K | 1 |
| Sabbaghziarani, F | 1 |
| Mortezaee, K | 1 |
| Akbari, M | 1 |
| Kashani, IR | 1 |
| Soleimani, M | 1 |
| Hassanzadeh, G | 1 |
| Zendedel, A | 1 |
| Neidert, S | 1 |
| Katan, M | 1 |
| Schuetz, P | 1 |
| Fluri, F | 1 |
| Ernst, A | 1 |
| Bingisser, R | 1 |
| Kappos, L | 1 |
| Engelter, ST | 1 |
| Steck, A | 1 |
| Müller, B | 1 |
| Christ-Crain, M | 1 |
| Schwarz, S | 1 |
| Schwab, S | 1 |
| Klinga, K | 1 |
| Maser-Gluth, C | 1 |
| Bettendorf, M | 1 |
| JAMIESON, KG | 1 |
| Detsky, ME | 1 |
| Chiu, L | 1 |
| Shandling, MR | 1 |
| Sproule, ME | 1 |
| Ursell, MR | 1 |
| Doyle, KP | 1 |
| Suchland, KL | 1 |
| Ciesielski, TM | 1 |
| Lessov, NS | 1 |
| Grandy, DK | 1 |
| Scanlan, TS | 1 |
| Stenzel-Poore, MP | 1 |
| Rastogi, L | 1 |
| Gupta, S | 1 |
| Godbole, MM | 1 |
| Shuaib, A | 1 |
| Ijaz, S | 1 |
| Hemmings, S | 1 |
| Galazka, P | 1 |
| Ishaqzay, R | 1 |
| Liu, L | 1 |
| Ravindran, J | 1 |
| Miyashita, H | 1 |
| Whitesall, SE | 1 |
| Mayor, GH | 1 |
| Nachreiner, RF | 1 |
| Zwemer, CF | 1 |
| D'Alecy, LG | 1 |
| Dolgov, AM | 1 |
| Stadnikov, AA | 1 |
| Rami, A | 1 |
| Krieglstein, J | 1 |
| Olsson, T | 1 |
| Asplund, K | 1 |
| Hägg, E | 1 |
| Ozeredenko, VG | 1 |
| Fedorova, LP | 1 |
| Mikhaĭlova, EIu | 1 |
| Wicomb, WN | 1 |
| Cooper, DK | 1 |
| Novitzky, D | 1 |
1 review available for thyroxine and Brain Ischemia
| Article | Year |
|---|---|
Prognostic value of thyroid hormones in acute ischemic stroke - a meta analysis.
Topics: Animals; Brain Ischemia; Humans; Odds Ratio; Stroke; Thyroid Hormones; Thyrotropin; Thyroxine | 2017 |
21 other studies available for thyroxine and Brain Ischemia
| Article | Year |
|---|---|
Study of Thyroid Profi le in Patients with Ischemic Stroke at Presentation with Special Reference to Subclinical Hypothyroidism and Stroke Outcome.
Topics: Brain Ischemia; Humans; Hypothyroidism; Ischemic Stroke; Stroke; Thyrotropin; Thyroxine | 2020 |
Low TSH level predicts a poor clinical outcome in patients with anterior circulation ischemic stroke after endovascular thrombectomy.
Topics: Aged; Brain Ischemia; Female; Humans; Ischemic Stroke; Male; Middle Aged; Retrospective Studies; Thr | 2020 |
Free thyroxine and TSH interact with secreted protein acidic and rich in cysteine-like 1 in ischemic stroke.
Topics: Brain Ischemia; Cysteine; Humans; Osteonectin; Stroke; Thyrotropin; Thyroxine | 2018 |
Increased cardiovascular risk in thyroid cancer patients taking levothyroxine: a nationwide cohort study in Korea.
Topics: Adult; Brain Ischemia; Coronary Disease; Female; Health Surveys; Humans; Incidence; Male; Middle Age | 2019 |
The prognostic value of total T3 after acute cerebral infarction is age-dependent: a retrospective study on 768 patients.
Topics: Age Factors; Aged; Biomarkers; Brain Ischemia; Female; Humans; Male; Middle Aged; Odds Ratio; Progno | 2019 |
Thyroid function tests and early outcomes of acute ischemic stroke in older euthyroid patients.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Humans; Logistic Models; Male; Stroke; Thyroid Func | 2015 |
Low free triiodothyronine predicts poor functional outcome after acute ischemic stroke.
Topics: Aged; Biomarkers; Brain; Brain Ischemia; Female; Hospitalization; Humans; Logistic Models; Male; Pro | 2016 |
Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke.
Topics: Animals; Blotting, Western; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cytokines; Disease Mo | 2017 |
Anterior pituitary axis hormones and outcome in acute ischaemic stroke.
Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Epidemiologic Methods; Female; Human Growth Hor | 2011 |
Neuroendocrine changes in patients with acute space occupying ischaemic stroke.
Topics: Adrenocorticotropic Hormone; Brain; Brain Ischemia; Cerebrovascular Circulation; Combined Modality T | 2003 |
BILATERAL CAROTICO-CAVERNOUS FISTULAE. HYPOPITUITARISM FROM BILATERAL CAROTID LIGATION FOR SURGICAL CURE.
Topics: Accidents; Accidents, Traffic; Angiography; Arteriovenous Fistula; Blindness; Brain; Brain Damage, C | 1964 |
Clinical problem-solving. Heading down the wrong path.
Topics: Aphasia; Apraxias; Brain; Brain Diseases; Brain Ischemia; Brain Neoplasms; Cerebral Angiography; Dia | 2006 |
Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Ischemia; Cells, Cultured; Humans; Hypothermia; I | 2007 |
Pathophysiological basis for thyrotoxicosis as an aggravating factor in post-ischemic brain injury in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dose-Response Relationship, Drug; Glutathione; | 2008 |
Decreased glutamate release during hypothyroidism may contribute to protection in cerebral ischemia.
Topics: Animals; Brain Ischemia; Gerbillinae; Glutamates; Glutamic Acid; Hypothyroidism; Male; Microdialysis | 1994 |
Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs.
Topics: Animals; Brain Ischemia; Dogs; Heart Arrest; Male; Neurologic Examination; Radioimmunoassay; Resusci | 1996 |
[Dependence of the outcome of cerebral ischemia on the types of neurohypophysis reactions and dynamics of the level of hormones of hypophysis-dependent endocrine glands].
Topics: Animals; Brain Ischemia; Hydrocortisone; Male; Pituitary Gland, Posterior; Rats; Thyroxine; Time Fac | 1998 |
Thyroxine attenuates hippocampal neuronal damage caused by ischemia in the rat.
Topics: Animals; Brain Ischemia; Cell Death; Hippocampus; Male; Neurons; Rats; Rats, Inbred Strains; Thyroxi | 1992 |
Pituitary-thyroid axis, prolactin and growth hormone in patients with acute stroke.
Topics: Aged; Brain Ischemia; Female; Growth Hormone; Humans; Male; Prolactin; Thyrotropin; Thyrotropin-Rele | 1990 |
[Plasma levels of cyclic nucleotides, phosphodiesterase, thyroid hormones and insulin in patients with ischemic stroke].
Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Cyclic AMP; Cyclic GMP; Humans; Insulin; Nucleot | 1990 |
Impairment of renal slice function following brain death, with reversibility of injury by hormonal therapy.
Topics: Animals; Blood Pressure; Brain Death; Brain Ischemia; Cold Temperature; Hydrocortisone; Insulin; Kid | 1986 |