thyroxine has been researched along with Brain Injuries in 28 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that thyroglobulin (Tg) and free T4 (FT4) concentrations more than 2SD from the control mean are not increased in pregnancy in an iodine replete area in the absence of elevated TSH concentrations." | 7.72 | Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism. ( Faix, JD; Haddow, JE; Klein, RZ; Meter, RA; Mitchell, ML; Sargent, JD; Waisbren, SE, 2003) |
| " Those with GHD exhibited more rapid weight gain following injury than those without GHD and had lower levels of free thyroxine and follicle-stimulating hormone." | 3.76 | Traumatic brain injury in children and adolescents: surveillance for pituitary dysfunction. ( Blackman, JA; Buck, ML; Deboer, MD; Gurka, MJ; Kuperminc, MN; Norwood, KW; Patrick, PD; Rogol, AD; Wamstad, JB, 2010) |
| "To test the hypothesis that thyroglobulin (Tg) and free T4 (FT4) concentrations more than 2SD from the control mean are not increased in pregnancy in an iodine replete area in the absence of elevated TSH concentrations." | 3.72 | Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism. ( Faix, JD; Haddow, JE; Klein, RZ; Meter, RA; Mitchell, ML; Sargent, JD; Waisbren, SE, 2003) |
| "As a result, hypopituitarism is not a rare disease and should be recognised by the general practitioner." | 2.44 | Hypopituitarism. ( Aimaretti, G; Ghigo, E; Kreitschmann-Andermahr, I; Schneider, HJ; Stalla, GK, 2007) |
| "Hypopituitarism is rarely considered in patients who sustain traumatic brain injury and the neuropsychiatric manifestations of posttraumatic hypopituitarism have rarely been reported." | 1.33 | Neuropsychiatric disturbances and hypopituitarism after traumatic brain injury in an elderly man. ( Chang, YC; Tsai, JC; Tseng, FY, 2006) |
| "Hyperthyroidism was induced by subcutaneous injections of T_4." | 1.31 | Experimental hyperthyroidism increases the effectiveness of predegenerated peripheral nerve graft implantation into hippocampus of adult rats. ( Gołka, B; Granek, A; Larysz-Brysz, M; Lewin-Kowalik, J; Swiech-Sabuda, E, 2002) |
| "Prolonged coma afterhead trauma is associated with depletion of 3', 5' cyclic adenosine monophosphate (cAMP) in the cerebrospinal fluid (CSF)." | 1.26 | Hypothalamic hypothyroidism and hypogonadism in prolonged traumatic coma. ( Fleischer, AS; Payne, NS; Rudman, DR; Tindall, GT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bourgeois, A | 1 |
| Magazzeni, P | 1 |
| Audibert, G | 1 |
| Li, J | 1 |
| Donangelo, I | 1 |
| Abe, K | 1 |
| Scremin, O | 1 |
| Ke, S | 1 |
| Li, F | 1 |
| Milanesi, A | 1 |
| Liu, YY | 1 |
| Brent, GA | 1 |
| Kopczak, A | 1 |
| Kilimann, I | 1 |
| von Rosen, F | 3 |
| Krewer, C | 1 |
| Schneider, HJ | 4 |
| Stalla, GK | 4 |
| Schneider, M | 3 |
| Mori, Y | 1 |
| Tomonaga, D | 1 |
| Kalashnikova, A | 1 |
| Furuya, F | 1 |
| Akimoto, N | 1 |
| Ifuku, M | 1 |
| Okuno, Y | 1 |
| Beppu, K | 1 |
| Fujita, K | 1 |
| Katafuchi, T | 1 |
| Shimura, H | 1 |
| Churilov, LP | 1 |
| Noda, M | 1 |
| Shulga, A | 2 |
| Blaesse, A | 1 |
| Kysenius, K | 1 |
| Huttunen, HJ | 1 |
| Tanhuanpää, K | 1 |
| Saarma, M | 1 |
| Rivera, C | 2 |
| Srinivas, R | 1 |
| Brown, SD | 1 |
| Chang, YF | 1 |
| Garcia-Fillion, P | 1 |
| Adelson, PD | 1 |
| Randall, W | 1 |
| Liittschwager, J | 1 |
| Norwood, KW | 1 |
| Deboer, MD | 1 |
| Gurka, MJ | 1 |
| Kuperminc, MN | 1 |
| Rogol, AD | 1 |
| Blackman, JA | 1 |
| Wamstad, JB | 1 |
| Buck, ML | 1 |
| Patrick, PD | 1 |
| Chourdakis, M | 1 |
| Kraus, MM | 1 |
| Tzellos, T | 1 |
| Sardeli, C | 1 |
| Peftoulidou, M | 1 |
| Vassilakos, D | 1 |
| Kouvelas, D | 1 |
| Lewin-Kowalik, J | 1 |
| Gołka, B | 1 |
| Larysz-Brysz, M | 1 |
| Swiech-Sabuda, E | 1 |
| Granek, A | 1 |
| Meissner, W | 1 |
| Krapp, C | 1 |
| Kauf, E | 1 |
| Dohrn, B | 1 |
| Reinhart, K | 1 |
| Mitchell, ML | 1 |
| Klein, RZ | 1 |
| Sargent, JD | 1 |
| Meter, RA | 1 |
| Haddow, JE | 1 |
| Waisbren, SE | 1 |
| Faix, JD | 1 |
| Tatsumi, K | 1 |
| Haga, S | 1 |
| Matsuyoshi, H | 1 |
| Inoue, M | 1 |
| Manabe, T | 1 |
| Makinodan, M | 1 |
| Wanaka, A | 1 |
| Vasil'eva, EM | 1 |
| Shor, TA | 1 |
| Poddubnaia, AE | 1 |
| Saller, B | 2 |
| Petersenn, S | 1 |
| Uhr, M | 1 |
| Husemann, B | 1 |
| Chang, YC | 1 |
| Tsai, JC | 1 |
| Tseng, FY | 1 |
| Aimaretti, G | 1 |
| Kreitschmann-Andermahr, I | 1 |
| Ghigo, E | 1 |
| Tanriverdi, F | 1 |
| Ulutabanca, H | 1 |
| Unluhizarci, K | 1 |
| Selcuklu, A | 1 |
| Casanueva, FF | 1 |
| Kelestimur, F | 1 |
| Yassouridis, A | 1 |
| Barberá, M | 1 |
| Belda, FJ | 1 |
| Maruenda, A | 1 |
| Badenes, R | 1 |
| Frasquet, FJ | 1 |
| Chulia, V | 1 |
| Pinna, G | 1 |
| Meinhold, H | 1 |
| Hiedra, L | 1 |
| Thoma, R | 1 |
| Hoell, T | 1 |
| Gräf, KJ | 1 |
| Stoltenburg-Didinger, G | 1 |
| Eravci, M | 1 |
| Prengel, H | 1 |
| Brödel, O | 1 |
| Finke, R | 1 |
| Baumgartner, A | 1 |
| Fleischer, AS | 1 |
| Rudman, DR | 1 |
| Payne, NS | 1 |
| Tindall, GT | 1 |
| Gottardis, M | 1 |
| Nigitsch, C | 1 |
| Schmutzhard, E | 1 |
| Neumann, M | 1 |
| Putensen, C | 1 |
| Hackl, JM | 1 |
| Koller, W | 1 |
| Zhou, XP | 1 |
| Shutov, AA | 1 |
| Chudinov, AA | 1 |
| Papalia, D | 1 |
| Vigneri, R | 1 |
| Casale, P | 1 |
| Motta, L | 1 |
2 reviews available for thyroxine and Brain Injuries
| Article | Year |
|---|---|
Interplay between thyroxin, BDNF and GABA in injured neurons.
Topics: Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; gamma-Aminobutyric Acid; Humans; Neurons | 2013 |
Hypopituitarism.
Topics: Adrenocorticotropic Hormone; Brain Injuries; Female; Humans; Hypopituitarism; Luteinizing Hormone; M | 2007 |
2 trials available for thyroxine and Brain Injuries
| Article | Year |
|---|---|
Effect of early compared with delayed enteral nutrition on endocrine function in patients with traumatic brain injury: an open-labeled randomized trial.
Topics: Adolescent; Adult; Aged; APACHE; Brain Injuries; Endocrine System; Enteral Nutrition; Female; Humans | 2012 |
Thyroid hormone response to moderate hypothermia in severe brain injury.
Topics: Adult; Brain Injuries; Female; Humans; Hypothermia, Induced; Intensive Care Units; Male; Prospective | 2003 |
24 other studies available for thyroxine and Brain Injuries
| Article | Year |
|---|---|
Left ventricular failure after brain death: a room for L-thyroxine?
Topics: Accidents, Traffic; Brain Death; Brain Injuries; Cardiac Output; Humans; Male; Thyroxine; Tissue and | 2020 |
Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Brain Edema; Brain Injuries; Cell | 2017 |
Screening for hypopituitarism in 509 patients with traumatic brain injury or subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Brain Injuries; Cross-Sectional Studies; Estradiol; Female; Humans; Hydroco | 2014 |
Effects of 3,3',5-triiodothyronine on microglial functions.
Topics: Adenosine Triphosphate; Adjuvants, Pharmaceutic; Animals; Brain Injuries; Cell Movement; Cells, Cult | 2015 |
Thyroxin regulates BDNF expression to promote survival of injured neurons.
Topics: Animals; Axotomy; Biomarkers; Brain Injuries; Brain-Derived Neurotrophic Factor; Caspase 3; Cell Sur | 2009 |
Endocrine function in children acutely following severe traumatic brain injury.
Topics: Adolescent; Adrenocorticotropic Hormone; Brain Injuries; Child; Child, Preschool; Endocrine System; | 2010 |
The relationship between cyclic changes in thyroid function and behavior of cats with brain stem lesions.
Topics: Animals; Behavior, Animal; Brain Injuries; Brain Stem; Cats; Circadian Rhythm; Disease Models, Anima | 1967 |
Traumatic brain injury in children and adolescents: surveillance for pituitary dysfunction.
Topics: Adolescent; Arginine; Brain Injuries; Child; Female; Follicle Stimulating Hormone; Glucagon; Human G | 2010 |
Experimental hyperthyroidism increases the effectiveness of predegenerated peripheral nerve graft implantation into hippocampus of adult rats.
Topics: Animals; Brain Injuries; Cell Count; Cell Differentiation; Fluorescein-5-isothiocyanate; Graft Survi | 2002 |
Iodine sufficiency and measurements of thyroid function in maternal hypothyroidism.
Topics: Adult; Brain Injuries; Cross-Sectional Studies; Female; Fetal Diseases; Humans; Hypothyroidism; Immu | 2003 |
Characterization of cells with proliferative activity after a brain injury.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Antigens; Astrocytes; Biomarkers; Brain; Brain | 2005 |
[Changes of the thyroid hormone status in children with cerebral palsy and other neurological pathology].
Topics: Age Factors; Birth Injuries; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Cystitis; Fema | 2005 |
Prevalence of anterior pituitary insufficiency 3 and 12 months after traumatic brain injury.
Topics: Adult; Brain Injuries; Estradiol; Female; Follicle Stimulating Hormone; Human Growth Hormone; Humans | 2006 |
Neuropsychiatric disturbances and hypopituitarism after traumatic brain injury in an elderly man.
Topics: Aged; Brain Injuries; Cognition Disorders; Hormone Replacement Therapy; Humans; Hypopituitarism; Mal | 2006 |
Pituitary functions in the acute phase of traumatic brain injury: are they related to severity of the injury or mortality?
Topics: Adolescent; Adult; Age Factors; Aged; Brain Injuries; Female; Glasgow Coma Scale; Humans; Male; Midd | 2007 |
Predictors of anterior pituitary insufficiency after traumatic brain injury.
Topics: Adolescent; Adult; Aged; Brain Injuries; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hy | 2008 |
[Thyroid function in craniocerebral trauma (author's transl)].
Topics: Adolescent; Aged; Brain Injuries; Female; Humans; Male; Middle Aged; Prognosis; Radioimmunoassay; Th | 1982 |
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma; | 1997 |
Letter: Thyroid hormones in serious non-thyroidal illness.
Topics: Acute Disease; Anemia, Pernicious; Brain Injuries; Chronic Disease; Diabetic Coma; Diabetic Ketoacid | 1976 |
Hypothalamic hypothyroidism and hypogonadism in prolonged traumatic coma.
Topics: Adult; Brain Injuries; Coma; Cyclic AMP; Follicle Stimulating Hormone; Humans; Hypogonadism; Hypothy | 1978 |
The secretion of human growth hormone stimulated by human growth hormone releasing factor following severe cranio-cerebral trauma.
Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Growth Hormone; Growth Hormone-Releasing Hormone; | 1990 |
[Thyroid function in severe craniocerebral injuries].
Topics: Adult; Aged; Brain Injuries; Female; Humans; Male; Middle Aged; Prognosis; Thyroid Gland; Thyroxine; | 1987 |
[Disorders of thyroid function as a consequence of severe craniocerebral injury].
Topics: Acute Disease; Brain Concussion; Brain Injuries; Humans; Hypothalamo-Hypophyseal System; Thyroid Dis | 1988 |
[Considerations on a case of myxedema with lingual thyroid ectopia demonstrable with scintigraphy after exogenous thyrotropin stimulus].
Topics: Adult; Brain Injuries; Humans; Hypopituitarism; Male; Myxedema; Radionuclide Imaging; Thyroid Gland; | 1967 |