thyroxine has been researched along with Brain Edema in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heterozygous mutations in the thyroid hormone receptor alpha (THRA) gene cause resistance to thyroid hormone alpha (RTHα), a disease characterized by variable manifestations reminiscent of untreated congenital hypothyroidism but a raised triiodothyronine/thyroxine ratio and normal thyrotropin levels." | 3.85 | In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish. ( Carra, S; Cotelli, F; Marelli, F; Persani, L; Rurale, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Donangelo, I | 1 |
| Abe, K | 1 |
| Scremin, O | 1 |
| Ke, S | 1 |
| Li, F | 1 |
| Milanesi, A | 1 |
| Liu, YY | 1 |
| Brent, GA | 1 |
| Marelli, F | 1 |
| Carra, S | 1 |
| Rurale, G | 1 |
| Cotelli, F | 1 |
| Persani, L | 1 |
2 other studies available for thyroxine and Brain Edema
| Article | Year |
|---|---|
Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Brain Edema; Brain Injuries; Cell | 2017 |
In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish.
Topics: Anemia; Animals; Animals, Genetically Modified; Brain Edema; Congenital Hypothyroidism; Craniofacial | 2017 |