thyroxine has been researched along with Brain Disorders in 38 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present an unusual case of a 60 year old male who was noted to have primary hypothyroidism and decreased consciousness which did not respond to Levothyroxine." | 7.79 | A case of newly diagnosed primary hypothyroidism with deteriorating consciousness that did not respond to thyroxine--what else should be considered? ( Bondugulapati, R; Dixon, AN; Green, N; Harvey, J; Phyu, CT; Williams, A, 2013) |
| "We present an unusual case of a 60 year old male who was noted to have primary hypothyroidism and decreased consciousness which did not respond to Levothyroxine." | 3.79 | A case of newly diagnosed primary hypothyroidism with deteriorating consciousness that did not respond to thyroxine--what else should be considered? ( Bondugulapati, R; Dixon, AN; Green, N; Harvey, J; Phyu, CT; Williams, A, 2013) |
| "Hashimoto's encephalopathy is a subacute condition associated with autoimmune thyroiditis." | 2.41 | Hashimoto's encephalopathy. ( Chen, HC; Marsharani, U, 2000) |
| " Median (range) CBD time to maximum plasma concentration, maximum plasma concentration, and area under the concentration versus time curve up to 6 hours after dosing were 3." | 1.62 | Pharmacokinetics of cannabidiol in children with refractory epileptic encephalopathy. ( Agostini, S; Cáceres Guido, P; Caraballo, R; Fabiana Delaven, S; García Bournissen, F; Gutierrez, R; Huaman, M; Pérez Montilla, CA; Reyes, G; Riva, N; Schaiquevich, P, 2021) |
| "Patients with autoimmune thyroiditis-associated encephalopathy have high serum ENO1Ab titers." | 1.56 | Experimental evidence for alpha enolase as one potential autoantigen in the pathogenesis of both autoimmune thyroiditis and its related encephalopathy. ( Ding, S; Feng, Y; Li, J; Lu, Y; Qin, J; Shan, Z; Sun, R; Teng, W; Xiang, Y; Zhang, H, 2020) |
| "His longstanding CH was associated with empty sella syndrome, static encephalopathy, and severe musculoskeletal deformities." | 1.43 | Case Report: The Specter of Untreated Congenital Hypothyroidism in Immigrant Families. ( Drilling, A; Fischer, M; Hamdoun, E; Karachunski, P; Nathan, B; Petryk, A; Torkelson, JL, 2016) |
| "The diagnosis of Hashimoto's encephalopathy is made when no other cause is found for an acute encephalopathic illness, in the presence of positive thyroid autoantibodies, and is supported by a response to steroid therapy." | 1.40 | Endocrine encephalopathy. ( Hunt, P; Soule, S; Yong, KW, 2014) |
| "However, hypothyroidism is a rare cause of pseudo-obstruction so here we present a case report of Hashimoto's encephalopathy with gut pseudo-obstruction in an undiagnosed hypothyroid patient." | 1.40 | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. ( Bhat, MS; Shera, IA; Vyas, A; Yousuf, Q, 2014) |
| "Autoimmune encephalopathy associated with Hashimoto thyroiditis is already known to present with either stroke-like episodes or diffuse progressive deterioration." | 1.38 | A selective memory deficit caused by autoimmune encephalopathy associated with Hashimoto thyroiditis. ( Bonakis, A; Economou, A; Kalfakis, N; Koros, C; Mastorakos, G; Papageorgiou, SG, 2012) |
| "Hashimoto encephalopathy is a chronic relapsing steroid responsive encephalopathy characterized by antibodies against thyroid components." | 1.32 | [Hashimoto encephalopathy]. ( Günther, P; Kopf, A, 2004) |
| "This encephalopathy was alleviated and later disappeared following corticosteroid treatment." | 1.31 | Reversible white matter alterations in encephalopathy associated with autoimmune thyroid disease. ( Canton, A; Montalban, X; Pozo-Rosich, P; Rovira, A; Simo, R; Villoslada, P, 2002) |
| "Further, it demonstrated that TSH deficiency is not always permanent and the reevaluation of pituitary function is necessary." | 1.30 | Transient isolated thyrotropin deficiency associated with cavernous sinus syndrome. ( Endo, T; Haraguchi, K; Ohtaka, M; Onaya, T; Shimoda, H, 1998) |
| "Hashimoto's encephalopathy was diagnosed." | 1.30 | [Variable manifestations of Hashimoto's encephalopathy]. ( Haaxma, R; Schaafsma, A; van Oostrom, JC, 1999) |
| "A 63-year-old woman with longstanding spastic paraplegia and neurological evidence of long tract disturbance was found to have hypothyroidism, partial diabetes insipidus, hyperprolactinemia, and gonadotropin deficiency of hypothalamic origin." | 1.26 | Hypothalamic hypothyroidism causing spastic paraplegia: recovery following thyroid medication. ( Hills, JR; Jackson, IM; Kassirer, M; Papapetrou, PD, 1978) |
| "Following the development of Sheehan's syndrome, her insulin requirment decreased dramatically." | 1.26 | Sheehan's syndrome of hypothalamic origin in a woman with juvenile diabetes mellitus. ( Herbai, G; Werner, I, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (42.11) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 9 (23.68) | 29.6817 |
| 2010's | 8 (21.05) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Y | 1 |
| Qin, J | 1 |
| Xiang, Y | 1 |
| Sun, R | 1 |
| Feng, Y | 1 |
| Zhang, H | 1 |
| Ding, S | 1 |
| Li, J | 1 |
| Shan, Z | 1 |
| Teng, W | 1 |
| Cáceres Guido, P | 1 |
| Riva, N | 1 |
| Caraballo, R | 1 |
| Reyes, G | 1 |
| Huaman, M | 1 |
| Gutierrez, R | 1 |
| Agostini, S | 1 |
| Fabiana Delaven, S | 1 |
| Pérez Montilla, CA | 1 |
| García Bournissen, F | 1 |
| Schaiquevich, P | 1 |
| Williams, A | 1 |
| Green, N | 1 |
| Phyu, CT | 1 |
| Bondugulapati, R | 1 |
| Dixon, AN | 1 |
| Harvey, J | 1 |
| Pocsay, G | 1 |
| Gazdag, A | 1 |
| Engelhardt, J | 1 |
| Szaniszló, I | 1 |
| Szolnoki, Z | 1 |
| Forczek, G | 1 |
| Mikló, L | 1 |
| Yong, KW | 1 |
| Soule, S | 1 |
| Hunt, P | 1 |
| Shera, IA | 1 |
| Vyas, A | 1 |
| Bhat, MS | 1 |
| Yousuf, Q | 1 |
| Hamdoun, E | 1 |
| Karachunski, P | 1 |
| Nathan, B | 1 |
| Fischer, M | 1 |
| Torkelson, JL | 1 |
| Drilling, A | 1 |
| Petryk, A | 1 |
| Payer, J | 1 |
| Petrovic, T | 1 |
| Baqi, L | 1 |
| Lisy, L | 1 |
| Langer, P | 1 |
| Srivastava, B | 1 |
| Gelson, W | 1 |
| Griffiths, A | 1 |
| Filho, HC | 1 |
| Marui, S | 1 |
| Manna, TD | 1 |
| Brust, ES | 1 |
| Radonsky, V | 1 |
| Kuperman, H | 1 |
| Dichtchekenian, V | 1 |
| Setian, N | 1 |
| Damiani, D | 1 |
| Koros, C | 1 |
| Economou, A | 1 |
| Mastorakos, G | 1 |
| Bonakis, A | 1 |
| Kalfakis, N | 1 |
| Papageorgiou, SG | 1 |
| Pozo-Rosich, P | 1 |
| Villoslada, P | 1 |
| Canton, A | 1 |
| Simo, R | 1 |
| Rovira, A | 1 |
| Montalban, X | 1 |
| Avila, A | 1 |
| Serrado, A | 1 |
| Reig, L | 1 |
| Famades, A | 1 |
| Maho, P | 1 |
| TURPIN, R | 1 |
| ROCHE, J | 1 |
| SALABE, G | 1 |
| MICHEL, R | 1 |
| CRUVEILLER, J | 1 |
| STUTZEL, M | 1 |
| Mourão, CA | 1 |
| Schmidt, SL | 1 |
| Manhães, AC | 1 |
| Warren, CL | 1 |
| Sawhney, IM | 1 |
| Günther, P | 1 |
| Kopf, A | 1 |
| Detsky, ME | 1 |
| Chiu, L | 1 |
| Shandling, MR | 1 |
| Sproule, ME | 1 |
| Ursell, MR | 1 |
| Girling, J | 2 |
| de Swiet, M | 2 |
| Ohtaka, M | 1 |
| Haraguchi, K | 1 |
| Shimoda, H | 1 |
| Endo, T | 1 |
| Onaya, T | 1 |
| van Oostrom, JC | 1 |
| Schaafsma, A | 1 |
| Haaxma, R | 1 |
| Chen, HC | 1 |
| Marsharani, U | 1 |
| Andler, W | 1 |
| Stolecke, H | 1 |
| Kohns, U | 1 |
| Malinkovich, VD | 1 |
| Oleĭnik, VA | 1 |
| Burger, HG | 1 |
| Patel, YC | 1 |
| Jackson, IM | 1 |
| Papapetrou, PD | 1 |
| Hills, JR | 1 |
| Kassirer, M | 1 |
| Herbai, G | 1 |
| Werner, I | 1 |
| Hays, MT | 1 |
| Broome, MR | 1 |
| Turrel, JM | 1 |
| Takeda, K | 1 |
| Sakuta, M | 1 |
| Saeki, F | 1 |
| Thrush, DC | 1 |
| Boddie, HG | 1 |
| Mosonyi, L | 1 |
| Policzer, M | 1 |
| Szemere, P | 1 |
| Costom, BH | 1 |
| Grumbach, MM | 1 |
| Kaplan, SL | 1 |
| Snyder, PJ | 1 |
| Jacobs, LS | 1 |
| Rabello, MM | 1 |
| Sterling, FH | 1 |
| Shore, RN | 1 |
| Utiger, RD | 1 |
| Daughaday, WH | 1 |
| Shenkman, L | 1 |
| Mitsuma, T | 1 |
| Suphavai, A | 1 |
| Hollander, CS | 1 |
| Woolf, PD | 1 |
| Schalch, DS | 1 |
| Szántó, L | 1 |
| Mess, B | 1 |
| Reviczky, A | 1 |
| Hansen, JM | 1 |
| Siersbaek-Nielsen, K | 1 |
3 reviews available for thyroxine and Brain Disorders
| Article | Year |
|---|---|
Hashimoto's encephalopathy and rare cases of hyperthyroidism (review and case report).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Brain Diseases; Child; Cog | 2009 |
Hashimoto's encephalopathy.
Topics: Brain Diseases; Confusion; Contraindications; Electroencephalography; Follow-Up Studies; Glucocortic | 2000 |
Thyrotrophin releasing hormone--TSH.
Topics: Brain Diseases; Humans; Hyperthyroidism; Hypothalamus; Pituitary Diseases; Pituitary Gland; Pituitar | 1977 |
35 other studies available for thyroxine and Brain Disorders
| Article | Year |
|---|---|
Experimental evidence for alpha enolase as one potential autoantigen in the pathogenesis of both autoimmune thyroiditis and its related encephalopathy.
Topics: Animals; Antibodies; Autoantigens; Brain; Brain Diseases; Cytokines; Female; Maze Learning; Mice, In | 2020 |
Pharmacokinetics of cannabidiol in children with refractory epileptic encephalopathy.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Brain Diseases; Cannabidiol; Child; Child, Presch | 2021 |
A case of newly diagnosed primary hypothyroidism with deteriorating consciousness that did not respond to thyroxine--what else should be considered?
Topics: Brain Diseases; Consciousness; Diagnosis, Differential; Electroencephalography; Encephalitis; Glucoc | 2013 |
[Hashimoto encephalopathy].
Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Antipsychotic Agents; Autoantibodies; Brain Disease | 2013 |
Endocrine encephalopathy.
Topics: Autoantibodies; Brain Diseases; Encephalitis; Female; Follow-Up Studies; Hashimoto Disease; Humans; | 2014 |
Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Brain Diseases; Diagnosis, Differential; Encephalit | 2014 |
Case Report: The Specter of Untreated Congenital Hypothyroidism in Immigrant Families.
Topics: Adolescent; Brain Diseases; Child; Cognition Disorders; Congenital Hypothyroidism; Delayed Diagnosis | 2016 |
A confused patient with raised anti-thyroid antibodies--an unusual case.
Topics: Aged; Autoantibodies; Brain Diseases; Diagnosis, Differential; Electroencephalography; Encephalitis; | 2010 |
Novel mutation in MCT8 gene in a Brazilian boy with thyroid hormone resistance and severe neurologic abnormalities.
Topics: Amino Acid Sequence; Brain Diseases; Child; Humans; Male; Monocarboxylic Acid Transporters; Muscle H | 2011 |
A selective memory deficit caused by autoimmune encephalopathy associated with Hashimoto thyroiditis.
Topics: Attention; Brain Diseases; Dexamethasone; Executive Function; Female; Glucocorticoids; Hashimoto Dis | 2012 |
Reversible white matter alterations in encephalopathy associated with autoimmune thyroid disease.
Topics: Anti-Inflammatory Agents; Autoantibodies; Brain Diseases; Diagnosis, Differential; Female; Humans; M | 2002 |
Early presentation of gait disturbance in a steroid-responsive encephalopathy associated with autoimmune thyroiditis.
Topics: Aged; Brain Diseases; Female; Gait Disorders, Neurologic; Humans; Thyroiditis, Autoimmune; Thyroxine | 2003 |
[Characterization of o-methylthyroxin (new metabolite) in the urine of 2 encephalopathic, euthyroid children receiving L-thyroxin labeled with I-131].
Topics: Amino Acids, Aromatic; Body Fluids; Brain; Brain Diseases; Iodine; Iodine Radioisotopes; Thyroid Hor | 1961 |
Testosterone and free thyroxin blood in congenitally acallosal male BALB/cCF mice.
Topics: Agenesis of Corpus Callosum; Animals; Brain Diseases; Corpus Callosum; Incidence; Male; Mice; Mice, | 2003 |
Encephalopathy with hypothyroidism.
Topics: Brain Diseases; Confusion; Glucocorticoids; Humans; Male; Middle Aged; Prednisolone; Thyroiditis, Au | 2004 |
[Hashimoto encephalopathy].
Topics: Aged; Anticonvulsants; Brain Diseases; Carbamazepine; Dementia, Vascular; Diagnosis, Differential; D | 2004 |
Clinical problem-solving. Heading down the wrong path.
Topics: Aphasia; Apraxias; Brain; Brain Diseases; Brain Ischemia; Brain Neoplasms; Cerebral Angiography; Dia | 2006 |
Predictors of neonatal encephalopathy in full term infants. More information needed about possible role of thyroxine.
Topics: Brain Diseases; Female; Humans; Infant, Newborn; Maternal Exposure; Pregnancy; Prenatal Exposure Del | 1996 |
Transient isolated thyrotropin deficiency associated with cavernous sinus syndrome.
Topics: Aged; Brain Diseases; Cavernous Sinus; Dexamethasone; Drug Therapy, Combination; Follow-Up Studies; | 1998 |
[Variable manifestations of Hashimoto's encephalopathy].
Topics: Adult; Brain Diseases; Child; Electroencephalography; Female; Humans; Magnetic Resonance Imaging; Ma | 1999 |
Maternal thyroid disease: a risk factor for newborn encephalopathy.
Topics: Brain Diseases; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Risk Factors; T | 2001 |
Thyroid function in children with growth hormone deficiency, either idiopathic or caused by diseases of the central nervous system.
Topics: Adolescent; Birth Injuries; Brain Diseases; Child; Child, Preschool; Female; Growth Hormone; Humans; | 1978 |
[Thyrotropic, somatotropic and corticotropic functions of the hypophysis in thyrotoxicosis and postthyrotoxic encephalopathy].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Brain Diseases; Female; Growth Hormone; Humans; Hype | 1979 |
Hypothalamic hypothyroidism causing spastic paraplegia: recovery following thyroid medication.
Topics: Brain Diseases; Diabetes Insipidus; Female; Humans; Hypothalamus; Hypothyroidism; Middle Aged; Muscl | 1978 |
Sheehan's syndrome of hypothalamic origin in a woman with juvenile diabetes mellitus.
Topics: Adult; Brain Diseases; Diabetes Mellitus, Type 1; Ethinyl Estradiol; Female; Humans; Hydrocortisone; | 1976 |
Acute toxicity to vehicle in commercial radiothyronines.
Topics: Acetonitriles; Animals; Brain Diseases; Cats; Isotope Labeling; Male; Pharmaceutical Vehicles; Thyro | 1986 |
Central pontine myelinolysis diagnosed by magnetic resonance imaging.
Topics: Brain Diseases; Demyelinating Diseases; Drug Therapy, Combination; Female; Fludrocortisone; Humans; | 1985 |
Episodic encephalopathy associated with thyroid disorders.
Topics: Adult; Brain Diseases; Cyclophosphamide; Dexamethasone; Epilepsy, Tonic-Clonic; Female; Humans; Male | 1974 |
[An unusual case of hypermetabolism caused by hypofunction of the pituitary gland].
Topics: Adult; Brain Diseases; Diagnosis, Differential; Female; Guanethidine; Humans; Hyperthyroidism; Hypot | 1966 |
Effect of thyrotropin-releasing factor on serum thyroid-stimulating hormone. An approach to distinguishing hypothalamic from pituitary forms of idiopathic hypopituitary dwarfism.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Brain Diseases; Child; Diagnosis, Differential; Dwar | 1971 |
Diagnostic value of thyrotrophin-releasing hormone in pituitary and hypothalamic diseases. Assessment of thyrotrophin and prolactin secretion in 100 patients.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Diseases; Brain Neoplasms; Drug Evaluati | 1974 |
Hypothalamic hypothyroidism.
Topics: Agenesis of Corpus Callosum; Body Height; Brain Diseases; Diabetes Mellitus; Humans; Hypothalamus; H | 1972 |
Hypopituitarism secondary to hypothalamic insufficiency.
Topics: Adult; Brain Diseases; Clomiphene; Female; Follicle Stimulating Hormone; Growth Hormone; Humans; Hyd | 1973 |
Interrelations of thyroid and mesencephalic activity.
Topics: Adolescent; Animals; Brain Diseases; Cerebellar Nuclei; Congenital Hypothyroidism; Diencephalon; Fem | 1970 |
Cerebrospinal fluid thyroxine.
Topics: Blood-Brain Barrier; Brain Diseases; Dialysis; Humans; Hyperthyroidism; Hypothyroidism; Kidney Neopl | 1969 |