thyroxine has been researched along with Blood Poisoning in 41 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The principal thyroxine (T4) binding proteins were measured in 8 septic patients and 8 controls to determine the extent to which a decrease in their concentration contributes to the decrease in serum T4 in sepsis." | 9.09 | Concordant decreases of thyroxine and thyroxine binding protein concentrations during sepsis. ( Afandi, B; Schussler, GC; Vera, R; Yap, MG, 2000) |
| "The effects of acute Salmonella typhimurium sepsis on the kinetics of peripheral L-thyroxine (T(4)) distribution and metabolism and on serum total and free T(4) concentrations were studied in rhesus monkeys inoculated i." | 7.65 | Accelerated cellular uptake and metabolism of L-thyroxine during acute Salmonella typhimurium sepsis. ( DeRubertis, FR; Woeber, KA, 1973) |
| "To analyse the influence of selenium substitution on thyroid hormone metabolism in patients with severe sepsis." | 5.11 | Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients. ( Angstwurm, MW; Gaertner, R; Schopohl, J, 2004) |
| "The principal thyroxine (T4) binding proteins were measured in 8 septic patients and 8 controls to determine the extent to which a decrease in their concentration contributes to the decrease in serum T4 in sepsis." | 5.09 | Concordant decreases of thyroxine and thyroxine binding protein concentrations during sepsis. ( Afandi, B; Schussler, GC; Vera, R; Yap, MG, 2000) |
| "Studies have documented a correlation between hypothyroxinemia and mortality in critically ill patients; however, there are limited data in sepsis." | 3.78 | The identification of thyroid dysfunction in surgical sepsis. ( Moore, FA; Moore, LJ; Sim, V; Sucher, JF; Todd, SR; Turner, KL, 2012) |
| " Twenty patients suffering from severe non-endocrine diseases (septicaemia, fulminant hepatic and renal failure, acute pancreatitis, polytrauma, cerebral haemorrhage) were found to have serum thyroxine levels in the hypothyroid range (less than 4 micrograms/dl)." | 3.66 | Pituitary-thyroid dysfunction in severe non-thyroidal disease: "low-T4 syndrome". ( Bratusch-Marrain, P; Grubeck-Loebenstein, B; Kleinberger, G; Vierhapper, H; Waldhäusl, W, 1982) |
| "Depressed triiodothyronine and elevated reverse triiodothyronine levels are commonly seen in patients with acute and chronic illness and in patients receiving markedly hypocaloric diets." | 3.66 | Altered thyroid hormone levels in bacterial sepsis: the role of nutritional adequacy. ( Molitch, ME; O'Donnell, TF; Richmand, DA, 1980) |
| "The effects of acute Salmonella typhimurium sepsis on the kinetics of peripheral L-thyroxine (T(4)) distribution and metabolism and on serum total and free T(4) concentrations were studied in rhesus monkeys inoculated i." | 3.65 | Accelerated cellular uptake and metabolism of L-thyroxine during acute Salmonella typhimurium sepsis. ( DeRubertis, FR; Woeber, KA, 1973) |
| "Most patients with septic shock have low serum thyroid hormone levels, a condition known as non-thyroidal illness syndrome." | 2.94 | Non-thyroidal illness syndrome, the hidden player in the septic shock induced myocardial contractile depression. ( Lado-Abeal, J, 2020) |
| "Sepsis is a systemic inflammatory response syndrome with high mortality." | 1.62 | Thyroid hormone levels as a predictor marker predict the prognosis of patients with sepsis. ( Hong, G; Lu, Z; Sun, F; Wang, Y, 2021) |
| "Children with sepsis have a higher incidence rate of NTIS than those without sepsis." | 1.56 | [Association of non-thyroidal illness syndrome with interleukin-6 and interleukin-10 in critically ill children with sepsis]. ( Bai, XF; Cao, LJ; Kang, L; Li, LJ; Liu, G; Shi, XN; Xu, MX; Zhao, X, 2020) |
| "Sepsis is a life-threatening organ dysfunction caused by a dysregulated host reaction to infection." | 1.51 | Thyroid hormones as potential prognostic factors in sepsis. ( Dudek, A; Foks, M; Fronczek, J; Nowak-Kózka, I; Polok, K; Szczeklik, W, 2019) |
| "The incidence of cerebral infarction is increased in patients with NFPA irrespective of GHRT." | 1.48 | Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement ( Bengtsson, O; Bryngelsson, IL; Hammarstrand, C; Johannsson, G; Olsson, DS; Ragnarsson, O, 2018) |
| "Sepsis was a systemic response to a local infection." | 1.43 | Sepsis leads to thyroid impairment and dysfunction in rat model. ( Lin, X; Shi, S, 2016) |
| "After sepsis was cured, there was no hormonal change, except in 3 NT." | 1.42 | Nonthyroidal illnesses syndrome in full-term newborns with sepsis. ( Araujo, MC; Carvalho, WB; Ceccon, ME; Diniz, EM; Silva, MH, 2015) |
| "We found that in both patients with severe sepsis, and our rodent model, low plasma T(4) concentrations were inversely correlated with plasma MIF concentrations." | 1.37 | Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity. ( Al-Abed, Y; Aljabari, B; Blau, S; Cheng, KF; Coleman, T; Lee, H; Metz, CN; Meurice, N; Miller, EJ; Ochani, M; Pavlov, VA; Tracey, KJ; VanPatten, S, 2011) |
| "Compared with the control group and non-severe sepsis cases, the levels of free T3 (FT3), free T4 (FT4), T3, T4 and monocyte HLA-DR expression were significantly lower in severe sepsis cases (P<0." | 1.36 | [Changes of thyroxin and monocyte human leukocyte antigen-DR expression in senior patients with sepsis]. ( Feng, DG; Guo, ZH; Su, L; Wu, J; Xiong, RC; Xu, C; Yu, Z; Zhang, YY, 2010) |
| "Twenty-four children (13 boys) with septic shock and 25 children (14 boys) with sepsis were enrolled." | 1.34 | Thyroid function in children with sepsis and septic shock. ( Arun, S; Kabra, SK; Lodha, R; Sarthi, M; Vivekanandhan, S, 2007) |
| "Chorioamnionitis was stratified by subtype and again no association with CLD was seen in the population as a whole." | 1.31 | Placental and other perinatal risk factors for chronic lung disease in very low birth weight infants. ( Hack, M; Redline, RW; Wilson-Costello, D, 2002) |
| "Iodine metabolism was studied by organ radioassay and by imaging with a multiwire proportional chamber (MWPC) at various time intervals after intravenous injection of 125I." | 1.26 | Marked suppression of thyroid function in rats with gram-negative septicemia. ( Chang, LT; Garcia, JF; Kan, MK; Linfoot, JA; McCrae, J; Perez-Mendez, V, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (34.15) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 12 (29.27) | 24.3611 |
| 2020's | 4 (9.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chaudhary, S | 1 |
| Das, L | 1 |
| Sharma, N | 2 |
| Sachdeva, N | 1 |
| Bhansali, A | 2 |
| Dutta, P | 2 |
| Foks, M | 1 |
| Dudek, A | 1 |
| Polok, K | 1 |
| Nowak-Kózka, I | 1 |
| Fronczek, J | 1 |
| Szczeklik, W | 1 |
| Lado-Abeal, J | 1 |
| Xu, MX | 1 |
| Liu, G | 1 |
| Cao, LJ | 1 |
| Bai, XF | 1 |
| Kang, L | 1 |
| Zhao, X | 1 |
| Shi, XN | 1 |
| Li, LJ | 1 |
| Wang, Y | 1 |
| Sun, F | 1 |
| Hong, G | 1 |
| Lu, Z | 1 |
| Hammarstrand, C | 1 |
| Ragnarsson, O | 1 |
| Bengtsson, O | 1 |
| Bryngelsson, IL | 1 |
| Johannsson, G | 1 |
| Olsson, DS | 1 |
| Papastathi, C | 1 |
| Mavrommatis, A | 1 |
| Mentzelopoulos, S | 1 |
| Konstandelou, E | 1 |
| Alevizaki, M | 1 |
| Zakynthinos, S | 1 |
| Silva, MH | 1 |
| Araujo, MC | 1 |
| Diniz, EM | 1 |
| Ceccon, ME | 1 |
| Carvalho, WB | 1 |
| Lin, X | 1 |
| Shi, S | 2 |
| Wu, J | 1 |
| Zhang, YY | 1 |
| Feng, DG | 1 |
| Xu, C | 1 |
| Xiong, RC | 1 |
| Yu, Z | 2 |
| Guo, ZH | 1 |
| Su, L | 1 |
| Kurt, A | 1 |
| Aygun, AD | 1 |
| Sengul, I | 1 |
| Sen, Y | 1 |
| Citak Kurt, AN | 1 |
| Ustundag, B | 1 |
| Meyer, S | 1 |
| Schuetz, P | 1 |
| Wieland, M | 1 |
| Nusbaumer, C | 1 |
| Mueller, B | 1 |
| Christ-Crain, M | 1 |
| Al-Abed, Y | 1 |
| Metz, CN | 1 |
| Cheng, KF | 1 |
| Aljabari, B | 1 |
| VanPatten, S | 1 |
| Blau, S | 1 |
| Lee, H | 1 |
| Ochani, M | 1 |
| Pavlov, VA | 1 |
| Coleman, T | 1 |
| Meurice, N | 1 |
| Tracey, KJ | 1 |
| Miller, EJ | 1 |
| Dilli, D | 1 |
| Dilmen, U | 1 |
| Wang, T | 1 |
| Xu, L | 1 |
| Huang, CX | 1 |
| Todd, SR | 1 |
| Sim, V | 1 |
| Moore, LJ | 1 |
| Turner, KL | 1 |
| Sucher, JF | 1 |
| Moore, FA | 1 |
| Das, BK | 1 |
| Agarwal, P | 1 |
| Agarwal, JK | 1 |
| Mishra, OP | 1 |
| Redline, RW | 1 |
| Wilson-Costello, D | 1 |
| Hack, M | 1 |
| Angstwurm, MW | 1 |
| Schopohl, J | 1 |
| Gaertner, R | 1 |
| Lodha, R | 1 |
| Vivekanandhan, S | 1 |
| Sarthi, M | 1 |
| Arun, S | 1 |
| Kabra, SK | 1 |
| Masoodi, SR | 1 |
| Bhadada, S | 1 |
| Rajput, R | 1 |
| Fallon, JJ | 1 |
| Yelovich, RM | 1 |
| Green, PJ | 1 |
| Sidiropoulos, D | 1 |
| Vierhapper, H | 2 |
| Laggner, A | 1 |
| Waldhäusl, W | 2 |
| Grubeck-Loebenstein, B | 2 |
| Kleinberger, G | 2 |
| Bratusch-Marrain, P | 1 |
| Schönberger, W | 2 |
| Grimm, W | 2 |
| Emmrich, P | 1 |
| Gempp, W | 2 |
| Richmand, DA | 1 |
| Molitch, ME | 1 |
| O'Donnell, TF | 1 |
| Pinna, G | 1 |
| Meinhold, H | 1 |
| Hiedra, L | 1 |
| Thoma, R | 1 |
| Hoell, T | 1 |
| Gräf, KJ | 1 |
| Stoltenburg-Didinger, G | 1 |
| Eravci, M | 1 |
| Prengel, H | 1 |
| Brödel, O | 1 |
| Finke, R | 1 |
| Baumgartner, A | 1 |
| Mönig, H | 1 |
| Arendt, T | 1 |
| Meyer, M | 1 |
| Kloehn, S | 1 |
| Bewig, B | 1 |
| Vaidya, SJ | 1 |
| Atra, A | 1 |
| Bahl, S | 1 |
| Pinkerton, CR | 1 |
| Calvagna, V | 1 |
| Horton, C | 1 |
| Milan, S | 1 |
| Shepherd, V | 1 |
| Brain, C | 1 |
| Treleaven, J | 1 |
| Powles, R | 1 |
| Tait, D | 1 |
| Meller, ST | 1 |
| Afandi, B | 1 |
| Vera, R | 1 |
| Schussler, GC | 2 |
| Yap, MG | 2 |
| Jirasakuldech, B | 1 |
| Drew, H | 1 |
| Josephson, A | 1 |
| Michl, J | 1 |
| Dinkel, E | 1 |
| Kan, MK | 1 |
| Garcia, JF | 1 |
| McCrae, J | 1 |
| Chang, LT | 1 |
| Linfoot, JA | 1 |
| Perez-Mendez, V | 1 |
| Jia, XM | 1 |
| Dennhardt, R | 1 |
| Gramm, HJ | 1 |
| Meinhold, K | 1 |
| Voigt, K | 1 |
| Shambaugh, GE | 2 |
| Beisel, WR | 2 |
| Derubertis, FR | 2 |
| Woeber, KA | 1 |
| Cryer, PE | 1 |
| Herman, CM | 1 |
| Sode, J | 1 |
4 trials available for thyroxine and Blood Poisoning
| Article | Year |
|---|---|
Non-thyroidal illness syndrome, the hidden player in the septic shock induced myocardial contractile depression.
Topics: Euthyroid Sick Syndromes; Humans; Prospective Studies; Sepsis; Shock, Septic; Thyroxine | 2020 |
Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients.
Topics: Antioxidants; APACHE; Critical Illness; Female; Glutathione; Humans; Iodide Peroxidase; Male; Middle | 2004 |
Autologous bone marrow transplantation for childhood acute lymphoblastic leukaemia in second remission - long-term follow-up.
Topics: Adolescent; Bone Marrow Transplantation; Cataract; Child; Child, Preschool; Disease-Free Survival; F | 2000 |
Concordant decreases of thyroxine and thyroxine binding protein concentrations during sepsis.
Topics: Adult; Female; Humans; Immunodiffusion; Male; Middle Aged; Prealbumin; Protein Binding; Radioimmunoa | 2000 |
37 other studies available for thyroxine and Blood Poisoning
| Article | Year |
|---|---|
Utility of myxedema score as a predictor of mortality in myxedema coma.
Topics: Coma; Female; Hospital Mortality; Humans; Hypothyroidism; Male; Myxedema; Retrospective Studies; Sep | 2023 |
Thyroid hormones as potential prognostic factors in sepsis.
Topics: Aged; Female; Humans; Intensive Care Units; Male; Middle Aged; Poland; Prevalence; Prognosis; Prospe | 2019 |
[Association of non-thyroidal illness syndrome with interleukin-6 and interleukin-10 in critically ill children with sepsis].
Topics: Child; Critical Illness; Euthyroid Sick Syndromes; Humans; Interleukin-10; Interleukin-6; Retrospect | 2020 |
Thyroid hormone levels as a predictor marker predict the prognosis of patients with sepsis.
Topics: Aged; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Organ Dysfunction Scores; Pred | 2021 |
Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement
Topics: Adenoma; Adult; Aged; Cerebral Infarction; Cohort Studies; Comorbidity; Diabetes Mellitus, Type 2; F | 2018 |
Insulin-like Growth Factor I and its binding protein 3 in sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Case-Control Studies; Fe | 2013 |
Nonthyroidal illnesses syndrome in full-term newborns with sepsis.
Topics: Disease Progression; Euthyroid Sick Syndromes; Humans; Infant; Infant, Newborn; Sepsis; Shock, Septi | 2015 |
Sepsis leads to thyroid impairment and dysfunction in rat model.
Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression Regulation; Humans; Rats; Sepsis; Thyroi | 2016 |
[Changes of thyroxin and monocyte human leukocyte antigen-DR expression in senior patients with sepsis].
Topics: Aged; Aged, 80 and over; Case-Control Studies; Female; HLA-DR Antigens; Humans; Male; Monocytes; Pne | 2010 |
Serum thyroid hormones levels are significantly decreased in septic neonates with poor outcome.
Topics: Anti-Bacterial Agents; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newbo | 2011 |
Low triiodothyronine syndrome: a prognostic marker for outcome in sepsis?
Topics: Aged; Biomarkers; Critical Care; Euthyroid Sick Syndromes; Female; Health Status Indicators; Humans; | 2011 |
Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity.
Topics: Animals; Binding Sites; Humans; Inflammation; Macrophage Migration-Inhibitory Factors; Mice; Mice, K | 2011 |
The role of interleukin-6 and C-reactive protein in non-thyroidal illness in premature infants followed in neonatal intensive care unit.
Topics: C-Reactive Protein; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Intensive Care Unit | 2012 |
Thyroid hormone increased L-type calcium channel mRNA expression and L-type calcium current of myocytes in rabbits.
Topics: Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; Gene Expression Regulation; Heart Atria | 2012 |
The identification of thyroid dysfunction in surgical sepsis.
Topics: Euthyroid Sick Syndromes; Female; Humans; Male; Middle Aged; Retrospective Studies; Sepsis; Thyrotro | 2012 |
Serum cortisol and thyroid hormone levels in neonates with sepsis.
Topics: Humans; Hydrocortisone; Infant, Newborn; Sepsis; Thyroid Hormones; Thyroxine; Triiodothyronine | 2002 |
Placental and other perinatal risk factors for chronic lung disease in very low birth weight infants.
Topics: Adult; Arteriosclerosis; Black People; Chorioamnionitis; Chronic Disease; Cohort Studies; Ductus Art | 2002 |
Thyroid function in children with sepsis and septic shock.
Topics: Child; Female; Humans; Male; Prospective Studies; Sepsis; Shock, Septic; Thyroid Hormones; Thyrotrop | 2007 |
Predictors of outcome in myxoedema coma: a study from a tertiary care centre.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Female; Humans; Hydrocortisone; Male; Multiple Organ Failure | 2008 |
Euthyroid sick syndrome. Association with urosepsis in an elderly man.
Topics: Aged; Dopamine; Humans; Hypotension; Hypothyroidism; Male; Proteus Infections; Proteus mirabilis; Se | 1984 |
[Mortality and morbidity of premature infants].
Topics: Betamethasone; Female; Humans; Hyaline Membrane Disease; Infant Mortality; Infant, Newborn; Infant, | 1984 |
Impaired secretion of TSH in critically ill patients with 'low T4-syndrome'.
Topics: Adult; Aged; Bacterial Infections; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone | 1982 |
Pituitary-thyroid dysfunction in severe non-thyroidal disease: "low-T4 syndrome".
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aged; Critical Care; Female; Hepatic Encephal | 1982 |
Reduction of mortality rate in premature infants by substitution of thyroid hormones.
Topics: Female; Germany, West; Humans; Hypothyroidism; Infant Mortality; Infant, Newborn; Infant, Premature; | 1981 |
Altered thyroid hormone levels in bacterial sepsis: the role of nutritional adequacy.
Topics: Acute Disease; Adult; Aged; Bacteria; Chronic Disease; Female; Humans; Male; Middle Aged; Nutritiona | 1980 |
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma; | 1997 |
Activation of the hypothalamo-pituitary-adrenal axis in response to septic or non-septic diseases--implications for the euthyroid sick syndrome.
Topics: Adult; Aged; Critical Care; Cytokines; Euthyroid Sick Syndromes; Female; Humans; Male; Middle Aged; | 1999 |
A characteristic serpin cleavage product of thyroxine-binding globulin appears in sepsis sera.
Topics: Adult; Female; Humans; Male; Molecular Weight; Neutrophils; Pancreatic Elastase; Peptide Fragments; | 2000 |
Transient hypothyroidism associated with prematurity, sepsis, and respiratory distress.
Topics: Birth Weight; Humans; Hypothyroidism; Infant, Newborn; Infant, Premature, Diseases; Respiratory Dist | 1979 |
Marked suppression of thyroid function in rats with gram-negative septicemia.
Topics: Animals; Escherichia coli Infections; Iodine; Iodine Radioisotopes; Male; Proteus Infections; Proteu | 1976 |
[Dynamic changes in serum levels of T3 and T4 in burn patients and its clinical significance].
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; | 1990 |
Patterns of endocrine secretion during sepsis.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Diiodothyronines; Hormones; Humans; Hyd | 1989 |
Alterations in thyroid physiology during pneumococcal septicemia in the rat.
Topics: Animals; Iodine Isotopes; Mice; Pneumococcal Infections; Rats; Sepsis; Thyroid Function Tests; Thyro | 1966 |
Deiodination of l-thyroxine in vitro by peripheral leukocytes from rhesus monkeys with bacterial sepsis.
Topics: Animals; Carbon Radioisotopes; Glucose; Haplorhini; In Vitro Techniques; Iodides; Iodine Radioisotop | 1974 |
Endocrine influences on altered hepatic tyrosine transaminase activity during pneumococcal septicemia in the rat.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Animals; Circadian Rhythm; Epinephrine; Hydr | 1968 |
Accelerated cellular uptake and metabolism of L-thyroxine during acute Salmonella typhimurium sepsis.
Topics: Animals; Blood Proteins; Haplorhini; Injections, Intravenous; Iodine; Isotonic Solutions; Kidney; Le | 1973 |
Carbohydrate metabolism in the baboon subjected to gram-negative (E. coli) septicemia. I. Hyperglycemia with depressed plasma insulin concentrations.
Topics: 17-Hydroxycorticosteroids; Animals; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen | 1971 |