Page last updated: 2024-11-06

thyroxine and Autism Spectrum Disorder

thyroxine has been researched along with Autism Spectrum Disorder in 6 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)

Research Excerpts

ExcerptRelevanceReference
"The influence of maternal levothyroxine treatment during pregnancy remains unclear."8.12Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022)
"The aim of our study was to assess the iodine status of Polish boys with severe autism compared to their healthy peers and evaluate the relationship between urinary iodine, thyroid hormones, body mass index and Autism Spectrum Disorder (ASD) symptomatology."7.83Iodine in autism spectrum disorders. ( Błażewicz, A; Dolliver, W; Kocjan, R; Korona-Glowniak, I; Makarewicz, A, 2016)
"The influence of maternal levothyroxine treatment during pregnancy remains unclear."4.12Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Li, GHY; Man, KKC; Wong, ICK, 2022)
"The aim of our study was to assess the iodine status of Polish boys with severe autism compared to their healthy peers and evaluate the relationship between urinary iodine, thyroid hormones, body mass index and Autism Spectrum Disorder (ASD) symptomatology."3.83Iodine in autism spectrum disorders. ( Błażewicz, A; Dolliver, W; Kocjan, R; Korona-Glowniak, I; Makarewicz, A, 2016)
"Maternal hypothyroidism was associated with ASD for both boys (3."1.48Association between maternal hypothyroidism and autism spectrum disorders in children. ( Chiu, VY; Fassett, MJ; Getahun, D; Jacobsen, SJ; Peltier, MR; Wing, DA; Xiang, AH, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Ge, GM1
Cheung, ECL1
Man, KKC1
Ip, P1
Leung, WC1
Li, GHY1
Kung, AWC1
Cheung, CL1
Wong, ICK1
Erbaş, İM1
Demir, K1
Getahun, D1
Jacobsen, SJ1
Fassett, MJ1
Wing, DA1
Xiang, AH1
Chiu, VY1
Peltier, MR1
Błażewicz, A1
Makarewicz, A1
Korona-Glowniak, I1
Dolliver, W1
Kocjan, R1
Lyall, K1
Anderson, M1
Kharrazi, M1
Windham, GC1
Frye, RE1
Wynne, R1
Rose, S1
Slattery, J1
Delhey, L1
Tippett, M1
Kahler, SG1
Bennuri, SC1
Melnyk, S1
Sequeira, JM1
Quadros, EV1

Reviews

1 review available for thyroxine and Autism Spectrum Disorder

ArticleYear
The Clinical Spectrum of Resistance to Thyroid Hormone Alpha in Children and Adults
    Journal of clinical research in pediatric endocrinology, 2021, 02-26, Volume: 13, Issue:1

    Topics: Adult; Autism Spectrum Disorder; Child; Constipation; Developmental Disabilities; Growth Disorders;

2021

Other Studies

5 other studies available for thyroxine and Autism Spectrum Disorder

ArticleYear
Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study.
    BMC medicine, 2022, 11-08, Volume: 20, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cohort Studies; Female; Hum

2022
Association between maternal hypothyroidism and autism spectrum disorders in children.
    Pediatric research, 2018, Volume: 83, Issue:3

    Topics: Adolescent; Age Factors; Autism Spectrum Disorder; Child; Child, Preschool; Female; Humans; Hypothyr

2018
Iodine in autism spectrum disorders.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2016, Volume: 34

    Topics: Adolescent; Autism Spectrum Disorder; Case-Control Studies; Child; Child, Preschool; Humans; Iodine;

2016
Neonatal thyroid hormone levels in association with autism spectrum disorder.
    Autism research : official journal of the International Society for Autism Research, 2017, Volume: 10, Issue:4

    Topics: Autism Spectrum Disorder; Birth Certificates; Child; Female; Humans; Infant, Newborn; Male; Neonatal

2017
Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder.
    Journal of neuroendocrinology, 2017, Volume: 29, Issue:3

    Topics: Autism Spectrum Disorder; Autoantibodies; Autoimmune Diseases; Case-Control Studies; Child; Child, P

2017