thyroxine has been researched along with Atheroma in 2 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Instability of atherosclerotic plaque in hypothyroidism could cause excessive activity of the elements of innate immunity, which are characterized by the significant presence of macrophages in atherosclerotic plaques, increased nuclear factor kappa B (NFkB) expression, and elevated levels of tumor necrosis factor α (TNF-α) and matrix metalloproteinase (MMP) 9, with reduced interstitial collagen; all of them together creates inflammation milieu, resulting in plaque rupture." | 2.82 | Hypothyroidism and Risk of Cardiovascular Disease. ( Gluvic, ZM; Isenovic, ER; Obradovic, MM; Rizzo, M; Sudar-Milovanovic, EM; Zafirovic, SS, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gluvic, ZM | 1 |
| Zafirovic, SS | 1 |
| Obradovic, MM | 1 |
| Sudar-Milovanovic, EM | 1 |
| Rizzo, M | 1 |
| Isenovic, ER | 1 |
| Marfella, R | 1 |
| Ferraraccio, F | 1 |
| Rizzo, MR | 1 |
| Portoghese, M | 1 |
| Barbieri, M | 1 |
| Basilio, C | 1 |
| Nersita, R | 1 |
| Siniscalchi, LI | 1 |
| Sasso, FC | 1 |
| Ambrosino, I | 1 |
| Siniscalchi, M | 1 |
| Maresca, L | 1 |
| Sardu, C | 1 |
| Amato, G | 1 |
| Paolisso, G | 1 |
| Carella, C | 1 |
1 review available for thyroxine and Atheroma
| Article | Year |
|---|---|
Hypothyroidism and Risk of Cardiovascular Disease.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Female; Humans; Hypothyroidism; Plaque, Atherosclero | 2022 |
1 other study available for thyroxine and Atheroma
| Article | Year |
|---|---|
Innate immune activity in plaque of patients with untreated and L-thyroxine-treated subclinical hypothyroidism.
Topics: Aged; Asymptomatic Diseases; Atherectomy; Case-Control Studies; Female; Hormone Replacement Therapy; | 2011 |