Page last updated: 2024-11-06

thyroxine and Asystole

thyroxine has been researched along with Asystole in 13 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
" In a previous investigation, post-resuscitation infusion of levothyroxine sodium (L-T4) to normalize serum 3,5,3'-triiodothyronine (T3) concentrations was associated with significant reduction of neurologic deficit caused by severe global cerebral ischemia."3.69Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs. ( D'Alecy, LG; Mayor, GH; Nachreiner, RF; Whitesall, SE; Zwemer, CF, 1996)
"Circulating concentrations of thyroxine (T4), triiodothyronine (T3), and reverse triiodothyronine (rT3) were followed in dogs subjected to 9 min of normothermic ventricular fibrillation."3.68Thyroid hormone loss and replacement during resuscitation from cardiac arrest in dogs. ( D'Alecy, LG; Facktor, MA; Mayor, GH; Nachreiner, RF, 1993)
"Fifty patients with cardiac arrest induced by ACS and 31 patients with acute myocardial infarction (AMI) who did not require cardioversion or cardiopulmonary resuscitation were enrolled in the study, as were 40 healthy volunteers."2.71Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome. ( Ariturk, Z; Iltumur, K; Olmez, G; Taskesen, T; Toprak, N, 2005)
"The treated group received a pre-cardiac arrest infusion of 15 micrograms/kg per h of LT4 for 1."1.30Acute thyroid hormone administration increases systemic oxygen delivery and consumption immediately following resuscitation from cardiac arrest without changes in thyroid-stimulating hormone. ( D'Alecy, LG; Mayor, GH; Nachreiner, RF; Whitesall, SE; Zwemer, CF, 1997)
"Hypothyroidism has generally been considered a contraindication to surgery."1.27Complications of surgery in hypothyroid patients. ( Daniels, GH; Ladenson, PW; Levin, AA; Ridgway, EC, 1984)
" In the thyrotoxic state, the higher dosage of phenylephrine increased peripheral resistance to the euthyroid control level and caused a small (6%) decrease in cardiac output (P less than 0."1.27Control of cardiac output in thyrotoxic calves. Evaluation of changes in the systemic circulation. ( Goldman, S; Morkin, E; Olajos, M, 1984)
"Thyroid function was evaluated in cardiac arrest (CA), a condition associated with marked activation of the pituitary-adrenal axis."1.27Hypothyroxinemia in cardiac arrest. ( Chopra, IJ; Murphy, JE; Premachandra, BN; Wortsman, J, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuryłowicz, A1
Niewiński, G1
Kański, A1
Derlatka, P1
Czajkowski, K1
Bednarczuk, T1
Ambroziak, U1
Iltumur, K1
Olmez, G1
Ariturk, Z1
Taskesen, T1
Toprak, N1
Ladenson, PW1
Levin, AA1
Ridgway, EC1
Daniels, GH1
Goldman, S1
Olajos, M1
Morkin, E1
Georgitis, WJ1
Hofeldt, FD1
Bacci, V1
Schussler, GC1
Bhogal, RS1
Carter, AC1
Facktor, MA1
Mayor, GH4
Nachreiner, RF3
D'Alecy, LG4
Whitesall, SE2
Zwemer, CF2
Longstreth, WT1
Manowitz, NR1
DeGroot, LJ1
Siscovick, DS1
Copass, MK1
Weinmann, S1
Cobb, LA1
Wortsman, J1
Premachandra, BN1
Chopra, IJ1
Murphy, JE1
Siess, M1

Trials

1 trial available for thyroxine and Asystole

ArticleYear
Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome.
    Critical care (London, England), 2005, Volume: 9, Issue:4

    Topics: Cardiopulmonary Resuscitation; Coronary Disease; Creatine Kinase, MB Form; Electric Countershock; Eu

2005

Other Studies

12 other studies available for thyroxine and Asystole

ArticleYear
Severe gestational hyperthyroidism complicated by cardiac arrest - a case report.
    Ginekologia polska, 2017, Volume: 88, Issue:1

    Topics: Abortion, Therapeutic; Adult; Antithyroid Agents; Cardiopulmonary Resuscitation; Female; Heart Arres

2017
Complications of surgery in hypothyroid patients.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adult; Aged; Cholecystectomy; Confusion; Constipation; Coronary Disease; Female; Heart Arrest; Human

1984
Control of cardiac output in thyrotoxic calves. Evaluation of changes in the systemic circulation.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:2

    Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cattle; Heart Arrest; Hemodynamics; Hyperthyr

1984
Myxedema coma and cardiac arrest.
    JAMA, 1982, Feb-19, Volume: 247, Issue:7

    Topics: Coma; Heart Arrest; Humans; Myxedema; Thyroxine

1982
Cardiac arrest after intravenous administration of levothyroxine.
    JAMA, 1981, Mar-06, Volume: 245, Issue:9

    Topics: Female; Heart Arrest; Humans; Injections, Intravenous; Middle Aged; Myxedema; Thyroxine

1981
Thyroid hormone loss and replacement during resuscitation from cardiac arrest in dogs.
    Resuscitation, 1993, Volume: 26, Issue:2

    Topics: Animals; Cardiopulmonary Resuscitation; Dogs; Euthyroid Sick Syndromes; Heart Arrest; Male; Thyroid

1993
Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs.
    Resuscitation, 1996, Volume: 33, Issue:1

    Topics: Animals; Brain Ischemia; Dogs; Heart Arrest; Male; Neurologic Examination; Radioimmunoassay; Resusci

1996
Plasma thyroid hormone profiles immediately following out-of-hospital cardiac arrest.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:6

    Topics: Aged; Female; Heart Arrest; Humans; Male; Middle Aged; Retrospective Studies; Thyroid Hormones; Thyr

1996
Acute thyroid hormone administration increases systemic oxygen delivery and consumption immediately following resuscitation from cardiac arrest without changes in thyroid-stimulating hormone.
    Resuscitation, 1997, Volume: 33, Issue:3

    Topics: Animals; Cardiopulmonary Resuscitation; Dogs; Heart Arrest; Humans; Male; Oxygen Consumption; Thyroi

1997
Thyroid hormone in neural rescue.
    Thyroid : official journal of the American Thyroid Association, 1997, Volume: 7, Issue:1

    Topics: Animals; Carbon Dioxide; Cardiac Output; Cardiopulmonary Resuscitation; Dogs; Heart Arrest; Hypothyr

1997
Hypothyroxinemia in cardiac arrest.
    Archives of internal medicine, 1987, Volume: 147, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Female; Heart Arrest; Humans; Male; Middle Aged; Thyroglobulin; Thyr

1987
Effects on efficiency and consumption of 14C-glucose and 14C-hexanoate in arrested and beating atria of guinea pigs.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Animals; Biomechanical Phenomena; Caproates; Carbon Isotopes; Glucose; Guinea Pigs; Heart Arrest; He

1968