thyroxine has been researched along with Arthritis, Rheumatoid in 34 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 20 female patients with CIU + AT, both hypothyroid and euthyroid, we have investigated the therapeutic effects of l-thyroxine dosed to suppress the TSH." | 5.33 | Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? ( Aversano, M; Caiazzo, P; Iorio, G; Laganá, B; Leccese, F; Ponticiello, L, 2005) |
| "65 years old male patient received 4 mg/day methylprednisolone baseline therapy and 50 mg/week etanercept treatment for 5 years due to rheumatoid arthritis." | 4.95 | [Etanercept-induced subacute thyroiditis. Case report and literature review]. ( Hella, Z; Hodinka, L; Kovács, GL; Turbucz, P, 2017) |
| " In order to determine the prevalence of thyroid function and autoimmune abnormalities, we compared serum thyrotropin (TSH, serum free thyroxine (T4) levels, thyroid antithyroglobulin (TgAb) and antithyroperoxidase (TPOAb) levels of 25 patients with systemic sclerosis, 25 patients with rheumatoid arthritis and 13 patients with antiphospholipid syndrome to a control group of 113 healthy individuals." | 3.72 | Thyroid autoantibodies in autoimmune diseases. ( Innocencio, RM; Romaldini, JH; Ward, LS, 2004) |
| "The rheumatoid nodule is the most common extra-articular manifestation of rheumatoid arthritis." | 1.51 | Rheumatoid nodules in thyroid gland parenchyma as an expression of rheumatoid arthritis: a case report. ( Arelaki, S; Giatromanolaki, A; Koukourakis, MI; Kouroupi, M; Lyratzopoulos, N; Sivridis, E, 2019) |
| "Chronic autoimmune thyroiditis (ATD) frequently overlaps with autoimmune rheumatic diseases." | 1.35 | Autoimmune thyroid disease and autoimmune rheumatic disorders: a two-sided analysis. ( Benhatchi, K; Kozáková, D; Lazúrová, I; Macejova, Z; Rovenský, J; Shoenfeld, Y; Tajtáková, M; Wagnerová, H, 2009) |
| "In 20 female patients with CIU + AT, both hypothyroid and euthyroid, we have investigated the therapeutic effects of l-thyroxine dosed to suppress the TSH." | 1.33 | Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? ( Aversano, M; Caiazzo, P; Iorio, G; Laganá, B; Leccese, F; Ponticiello, L, 2005) |
| "Impotence was reported by 6 of the patients with scleroderma and none with rheumatoid arthritis." | 1.27 | Impotence in scleroderma. ( Brick, JE; Carlson, HE; Judd, HL; Lu, JK; Nowlin, NS; Weaver, DJ; Wilson, DA, 1986) |
| "A 51-year-old woman with chronic lymphocytic thyroiditis showed transient thyrotoxicosis at seven weeks after cessation of steroid therapy for treatment of rheumatoid arthritis." | 1.26 | Transient thyrotoxicosis occurred after cessation of steroid therapy in a patient with autoimmune thyroiditis and rheumatoid arthritis. ( Kataoka, K; Kato, M; Maruyama, H; Matsuki, S; Mizuno, O, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (35.29) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SL | 1 |
| Xu, Q | 1 |
| Lin, CS | 1 |
| Nguyen, MVC | 1 |
| Courtier, A | 1 |
| Adrait, A | 1 |
| Defendi, F | 1 |
| Couté, Y | 1 |
| Baillet, A | 1 |
| Guigue, L | 1 |
| Gottenberg, JE | 1 |
| Dumestre-Pérard, C | 1 |
| Brun, V | 1 |
| Gaudin, P | 1 |
| Hella, Z | 1 |
| Hodinka, L | 1 |
| Turbucz, P | 1 |
| Kovács, GL | 1 |
| Waldenlind, K | 1 |
| Saevarsdottir, S | 2 |
| Bengtsson, C | 2 |
| Askling, J | 1 |
| Kumar, A | 1 |
| Agarwal, A | 1 |
| Sharma, A | 1 |
| Agarwal, D | 1 |
| Jain, N | 1 |
| Gupta, P | 1 |
| Sivridis, E | 1 |
| Kouroupi, M | 1 |
| Koukourakis, MI | 1 |
| Arelaki, S | 1 |
| Lyratzopoulos, N | 1 |
| Giatromanolaki, A | 1 |
| Padyukov, L | 1 |
| Källberg, H | 1 |
| Lazúrová, I | 1 |
| Benhatchi, K | 1 |
| Rovenský, J | 1 |
| Kozáková, D | 1 |
| Wagnerová, H | 1 |
| Tajtáková, M | 1 |
| Shoenfeld, Y | 1 |
| Macejova, Z | 1 |
| Raterman, HG | 1 |
| Jamnitski, A | 1 |
| Lems, WF | 1 |
| Voskuyl, AE | 1 |
| Dijkmans, BA | 1 |
| Bos, WH | 1 |
| Simsek, S | 1 |
| Lips, P | 1 |
| van de Stadt, RJ | 1 |
| de Koning, MH | 1 |
| Nurmohamed, MT | 1 |
| Geoghegan, JM | 1 |
| Clark, DI | 1 |
| Bainbridge, LC | 1 |
| Smith, C | 1 |
| Hubbard, R | 1 |
| Innocencio, RM | 1 |
| Romaldini, JH | 1 |
| Ward, LS | 1 |
| Aversano, M | 1 |
| Caiazzo, P | 1 |
| Iorio, G | 1 |
| Ponticiello, L | 1 |
| Laganá, B | 1 |
| Leccese, F | 1 |
| de Mast, Q | 1 |
| Haverman, J | 1 |
| Netten, PM | 1 |
| Sinnige, HA | 1 |
| Thomas, FB | 1 |
| Marktl, W | 1 |
| Shabtai, R | 1 |
| Shapiro, MS | 1 |
| Orenstein, D | 1 |
| Taragan, R | 1 |
| Shenkman, L | 1 |
| Weissel, M | 1 |
| Maruyama, H | 1 |
| Kato, M | 1 |
| Mizuno, O | 1 |
| Kataoka, K | 1 |
| Matsuki, S | 1 |
| Fowler, PD | 1 |
| Crook, PR | 1 |
| Hothersall, TE | 1 |
| Nagayama, Y | 1 |
| Harakawa, S | 1 |
| Taguchi, A | 1 |
| Takeshita, A | 1 |
| Eguchi, K | 1 |
| Yokoyama, N | 1 |
| Nagataki, S | 1 |
| Bianchi, G | 1 |
| Marchesini, G | 1 |
| Zoli, M | 1 |
| Falasconi, MC | 1 |
| Iervese, T | 1 |
| Vecchi, F | 1 |
| Magalotti, D | 1 |
| Ferri, S | 1 |
| Shiroky, JB | 1 |
| Cohen, M | 1 |
| Ballachey, ML | 1 |
| Neville, C | 1 |
| Norden, AG | 1 |
| Jackson, RA | 1 |
| Norden, LE | 1 |
| Griffin, AJ | 1 |
| Barnes, MA | 1 |
| Little, JA | 1 |
| Zenovko, EI | 1 |
| Pavlov, BA | 1 |
| Koreshkov, GG | 1 |
| Gudukina, GN | 1 |
| Sonkina, EG | 1 |
| Ilias, I | 1 |
| Mastorakos, G | 1 |
| Mavrikakis, M | 1 |
| Papazoglou, S | 1 |
| Karamitsos, D | 1 |
| Ntantis, P | 1 |
| Mantzos, E | 1 |
| Mantzos, I | 1 |
| Koutras, DA | 1 |
| Wellby, ML | 1 |
| Kennedy, JA | 1 |
| Pile, K | 1 |
| True, BS | 1 |
| Barreau, P | 1 |
| Sakata, S | 1 |
| Nagai, K | 1 |
| Shibata, T | 1 |
| Kamikubo, K | 1 |
| Tokimitsu, N | 1 |
| Kucera, M | 1 |
| Brabcová, H | 1 |
| McCrea, AP | 1 |
| Bell, AL | 1 |
| Nowlin, NS | 1 |
| Brick, JE | 1 |
| Weaver, DJ | 1 |
| Wilson, DA | 1 |
| Judd, HL | 1 |
| Lu, JK | 1 |
| Carlson, HE | 1 |
| Patwardhan, MH | 1 |
| Deodhar, SD | 1 |
| Dash, RJ | 1 |
| Kaur, M | 1 |
| Atreja, SK | 1 |
| Raab, W | 1 |
| Keil, I | 1 |
| Krzymień, H | 1 |
| Michalski, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis[NCT01000441] | Phase 4 | 300 participants (Actual) | Interventional | 2009-12-23 | Completed | ||
| BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900] | Phase 2 | 164 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | ||
| Basal Joint Arthroplasty and Carpal Tunnel Release Comparing Single Versus Double Incision. Randomized Clinical Trial[NCT04391751] | 40 participants (Actual) | Interventional | 2018-01-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thyroxine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
[Etanercept-induced subacute thyroiditis. Case report and literature review].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Humans; Male; Methylprednisolone; Thy | 2017 |
[Effect of non-thyroid diseases on serum concentrations of hormones of the thyroid function regulatory cycle].
Topics: Adolescent; Anorexia Nervosa; Arthritis, Rheumatoid; Female; Humans; Hyperthyroidism; Hypothyroidism | 1982 |
2 trials available for thyroxine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Diclofenac sodium and thyroid function tests.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; | 1982 |
Serum interleukin-6 and thyroid hormones in rheumatoid arthritis.
Topics: Aged; Aging; Arthritis, Rheumatoid; C-Reactive Protein; Diet; Female; Humans; Interleukin-6; Male; M | 2001 |
30 other studies available for thyroxine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Methotrexate is associated with decreased total thyroxine in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cross-Sectional Studies; Glucocorticoids; Humans; Methotrexate; Thyroxine | 2023 |
Fetuin-A and thyroxin binding globulin predict rituximab response in rheumatoid arthritis patients with insufficient response to anti-TNFα.
Topics: alpha-2-HS-Glycoprotein; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Proteomics; Rituximab; | 2020 |
Risk of Thyroxine-Treated Autoimmune Thyroid Disease Associated With Disease Onset in Patients With Rheumatoid Arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Male; Middle Aged; Prevale | 2018 |
Myxoedema coma following commencement of anti-TNF therapy and tuberculosis prophylaxis in a patient with RA and latent tuberculosis infection.
Topics: Aged; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Coma; Drug Therapy, Combin | 2019 |
Rheumatoid nodules in thyroid gland parenchyma as an expression of rheumatoid arthritis: a case report.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Greece; Humans; Rheumatoid Nodule; Thyro | 2019 |
Thyroxin substitution and the risk of developing rheumatoid arthritis; results from the Swedish population-based EIRA study.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Autoantibodies; Case-Control Studies; Female; Geneti | 2014 |
Autoimmune thyroid disease and autoimmune rheumatic disorders: a two-sided analysis.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Cell | 2009 |
Improvement of thyroid function in hypothyroid patients with rheumatoid arthritis after 6 months of adalimumab treatment: a pilot study.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Ag | 2011 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Thyroid autoantibodies in autoimmune diseases.
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Case-Control Studies; Female; Hum | 2004 |
Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response?
Topics: Adult; Antibodies; Antibody Formation; Arthritis, Rheumatoid; Blood Sedimentation; Chronic Disease; | 2005 |
Remission of a primary thyroid lymphoma after methotrexate withdrawal.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Hashimoto Disease; Humans; Lymphoma, B-Ce | 2006 |
Arthrodesis of the subtalar joint.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Arthrodesis; Calcaneus; Female; Flatfoot; Foot Disea | 1967 |
[Biological rhythms of various hormones and plasma protein parameters in the course of resort treatment].
Topics: Adult; Aged; alpha-Macroglobulins; Antibody Formation; Arthritis, Rheumatoid; Blood Proteins; Circad | 1983 |
The antithyroid arthritis syndrome reviewed.
Topics: Adult; Antithyroid Agents; Arthritis, Rheumatoid; Complement System Proteins; Female; Humans; Hypert | 1984 |
Transient thyrotoxicosis occurred after cessation of steroid therapy in a patient with autoimmune thyroiditis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chronic Disease; Dexamethasone; Female; Humans; Hyperthyroidism; Hypothyroidi | 1982 |
In vivo effect of gold compounds on thyroxine to triiodothyronine conversion by type I 5'-deiodinase in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Gold; Humans; Iodide Peroxidase; Male | 1993 |
Thyroid involvement in chronic inflammatory rheumatological disorders.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Arthritis, Rheumatoid; Autoantibodies; Chronic | 1993 |
Thyroid dysfunction in rheumatoid arthritis: a controlled prospective survey.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Humans; Male | 1993 |
Misleading results from immunoassays of serum free thyroxine in the presence of rheumatoid factor.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Humans; Immunoassay; Prospective Studies; Re | 1997 |
[Hypothalamo-pituitary-thyroid system in patients with rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Glucocorticoids; Humans; Hypothalamo-Hypophyseal System; | 1998 |
Thyroid disease associated with rheumatoid arthritis is not adequately screened with a sensitive chemiluminescence thyrotrophin assay.
Topics: Arthritis, Rheumatoid; Female; Humans; Luminescent Measurements; Male; Mass Screening; Middle Aged; | 1999 |
A case of rheumatoid arthritis associated with silent thyroiditis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Thyroid Function Tests; Thyroiditis; Thyroxine; Triiod | 1992 |
[Levels of tetra-, triiodothyronine and thyroid stimulating hormone in patients with rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Thyroid Function Tests; Thyrotropin; Thyro | 1990 |
Profound anaemia responding to correction of hypothyroidism in a patient with rheumatoid arthritis.
Topics: Adolescent; Anemia; Arthritis, Rheumatoid; Female; Humans; Hypothyroidism; Thyroxine | 1989 |
Impotence in scleroderma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Pressure; Erectile Dysfunction; Estradiol; Gonadotropins, | 1986 |
Circulating thyroid hormone levels in rheumatoid arthritis--a preliminary communication.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Thyrotropin; Thyroxine; | 1985 |
[The clinical significance of urinary hydroxyproline determinations (author's transl)].
Topics: Alkaline Phosphatase; Animals; Arthritis, Rheumatoid; Bone Diseases; Bone Neoplasms; Burns; Carbon R | 1972 |
[Thyroid hormones and progressive chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Male; Thyroid Diseases; Thyroxine | 1973 |
[Rheumatoid arthritis and thyroid hormones].
Topics: Arthritis, Rheumatoid; Calcitonin; Humans; Hyperthyroidism; Male; Methylthiouracil; Thyroidectomy; T | 1969 |