thyroxine has been researched along with Arthritis, Degenerative in 16 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the effect of the administration of meloxicam; carprofen; and a slow-acting disease modifying osteoarthritis agent, that contains chondroitin sulfate, purified glucosamine, and manganese ascorbate (CS-G-M), on thyroid function in dogs." | 7.72 | Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis. ( Beauchamp, G; Dupuis, J; Moreau, M; Paradis, M; Refsal, KR; Sauvé, F, 2003) |
| "Previous study indicated that the increase of local bio-availability of 3'3'5-triiodothyronine (T3) influenced osteoarthritis (OA) initiation." | 3.91 | Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone. ( Li, L; Li, M; Pang, Y; Wan, Y; Wang, J; Yin, Z; Zhu, C, 2019) |
| "The objective of this clinical study is to evaluate possible interactions between antiplatelet agents, anticoagulants, thyroid hormone replacement therapy and a formulation of curcumin (Meriva®) that resulted effective for the complementary treatment of osteoarthritis." | 3.88 | Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®). ( Belcaro, G; Cotellese, R; Dugall, M; Eggenhoffner, R; Giacomelli, L; Hosoi, M; Hu, S; Ledda, A; Peterzan, P; Riva, A; Togni, S, 2018) |
| "The purpose of this study was to evaluate the effect of the administration of meloxicam; carprofen; and a slow-acting disease modifying osteoarthritis agent, that contains chondroitin sulfate, purified glucosamine, and manganese ascorbate (CS-G-M), on thyroid function in dogs." | 3.72 | Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis. ( Beauchamp, G; Dupuis, J; Moreau, M; Paradis, M; Refsal, KR; Sauvé, F, 2003) |
| "Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes." | 1.46 | Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017) |
| "The study of osteoarthrosis (OA) course in the region of goiter endemia regarding thyroid status." | 1.31 | [Thyroid status and clinical features of osteoarthrosis in the region of goiter endemia]. ( Bagirova, VV; Boguslavskaia, MI; Turmukhambetova, BT, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S | 1 |
| Sun, X | 1 |
| Zhou, G | 1 |
| Jin, J | 1 |
| Li, Z | 1 |
| Li, L | 1 |
| Li, M | 1 |
| Pang, Y | 1 |
| Wang, J | 1 |
| Wan, Y | 1 |
| Zhu, C | 1 |
| Yin, Z | 1 |
| Hu, S | 1 |
| Belcaro, G | 1 |
| Dugall, M | 1 |
| Peterzan, P | 1 |
| Hosoi, M | 1 |
| Ledda, A | 1 |
| Riva, A | 1 |
| Giacomelli, L | 1 |
| Togni, S | 1 |
| Eggenhoffner, R | 1 |
| Cotellese, R | 1 |
| Askari, A | 1 |
| Ehrampoush, E | 1 |
| Homayounfar, R | 1 |
| Bahramali, E | 1 |
| Farjam, M | 1 |
| Rosario, M | 1 |
| Song, SX | 1 |
| McCullough, LD | 1 |
| Paradis, M | 2 |
| Sauvé, F | 2 |
| Charest, J | 1 |
| Refsal, KR | 2 |
| Moreau, M | 2 |
| Dupuis, J | 2 |
| Beauchamp, G | 1 |
| Ness, TA | 1 |
| Torres, SM | 1 |
| Kramek, EA | 1 |
| Blauvelt, MM | 1 |
| Geoghegan, JM | 1 |
| Clark, DI | 1 |
| Bainbridge, LC | 1 |
| Smith, C | 1 |
| Hubbard, R | 1 |
| Grenga, V | 1 |
| Schiavoni, R | 1 |
| Lubrano, C | 1 |
| Rosenberg, EF | 1 |
| Blivaiss, BB | 1 |
| Thomas, FB | 1 |
| Fowler, PD | 1 |
| Crook, PR | 1 |
| Hothersall, TE | 1 |
| Ilias, I | 1 |
| Mastorakos, G | 1 |
| Mavrikakis, M | 1 |
| Papazoglou, S | 1 |
| Karamitsos, D | 1 |
| Ntantis, P | 1 |
| Mantzos, E | 1 |
| Mantzos, I | 1 |
| Koutras, DA | 1 |
| Turmukhambetova, BT | 1 |
| Bagirova, VV | 1 |
| Boguslavskaia, MI | 1 |
| McConnell, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900] | Phase 2 | 164 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | ||
| Basal Joint Arthroplasty and Carpal Tunnel Release Comparing Single Versus Double Incision. Randomized Clinical Trial[NCT04391751] | 40 participants (Actual) | Interventional | 2018-01-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for thyroxine and Arthritis, Degenerative
| Article | Year |
|---|---|
Effect of dosing and sampling time on serum thyroxine, free thyroxine, and thyrotropin concentrations in dogs following multidose etodolac administration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Drug Administration Schedule; | 2003 |
Diclofenac sodium and thyroid function tests.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; | 1982 |
14 other studies available for thyroxine and Arthritis, Degenerative
| Article | Year |
|---|---|
Association between sensitivity to thyroid hormone indices and the risk of osteoarthritis: an NHANES study.
Topics: Female; Humans; Male; Nutrition Surveys; Osteoarthritis; Thyroid Hormones; Thyrotropin; Thyroxine; T | 2022 |
Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone.
Topics: Aged; Aged, 80 and over; Animals; Bone and Bones; China; Chondrocytes; Female; Humans; Injections, I | 2019 |
Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®).
Topics: Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Curcumin; Drug Compounding; Drug Interactions; | 2018 |
Serum insulin in pathogenesis and treatment of osteoarthritis.
Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression; | 2017 |
An unusual case of stroke.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diuretics; Female; Furo | 2012 |
Effects of moderate to severe osteoarthritis on canine thyroid function.
Topics: Animals; Autoantibodies; Case-Control Studies; Chronic Disease; Dog Diseases; Dogs; Euthyroid Sick S | 2003 |
Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Carbazoles; | 2003 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Risk factors in carpal tunnel syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Mass Index; Car | 2004 |
Osteoarthritis of the temporomandibular joint in an adult patient with Hashimoto thyroiditis: case report.
Topics: Adult; Female; Humans; Malocclusion, Angle Class II; Open Bite; Osteoarthritis; Osteotomy; Osteotomy | 2004 |
[Alkaptonuria and osteoarthritis. An experimental reproduction of primary human osteoarthritis].
Topics: Alkaptonuria; Animals; Culture Media; Osteoarthritis; Rats; Thyroxine | 1966 |
Arthrodesis of the subtalar joint.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Arthrodesis; Calcaneus; Female; Flatfoot; Foot Disea | 1967 |
Thyroid disease associated with rheumatoid arthritis is not adequately screened with a sensitive chemiluminescence thyrotrophin assay.
Topics: Arthritis, Rheumatoid; Female; Humans; Luminescent Measurements; Male; Mass Screening; Middle Aged; | 1999 |
[Thyroid status and clinical features of osteoarthrosis in the region of goiter endemia].
Topics: Adult; Aged; Endemic Diseases; Female; Goiter; Humans; Middle Aged; Osteoarthritis; Russia; Thyroid | 2000 |
Salsalate alters thyroid function test results.
Topics: Aged; Female; Humans; Osteoarthritis; Salicylates; Thyroid Function Tests; Thyrotropin; Thyroxine | 1989 |