thyroxine has been researched along with Apraxia of Gait in 1 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "They had similar clinical (macrocephaly, broad faces, skin tags, motor dyspraxia, slow speech), biochemical (subnormal ratio of free thyroxine:free tri-iodothyronine [T3], low concentration of total reverse T3, high concentration of creatine kinase, mild anaemia), and radiological (thickened calvarium) features to patients with TRα1-mediated resistance to thyroid hormone, although our patients had a heterozygous mis-sense mutation (Ala263Val) in both TRα1 and TRα2 proteins." | 1.40 | Resistance to thyroid hormone caused by a mutation in thyroid hormone receptor (TR)α1 and TRα2: clinical, biochemical, and genetic analyses of three related patients. ( Agostini, M; Aylwin, S; Buchanan, C; Chatterjee, KK; Chrysis, D; Efthymiadou, A; Gurnell, M; Halsall, D; Lyons, G; Moran, C; Offiah, AC; Poole, K; Rajanayagam, O; Schoenmakers, E; Schoenmakers, N; Visser, WE, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moran, C | 1 |
| Agostini, M | 1 |
| Visser, WE | 1 |
| Schoenmakers, E | 1 |
| Schoenmakers, N | 1 |
| Offiah, AC | 1 |
| Poole, K | 1 |
| Rajanayagam, O | 1 |
| Lyons, G | 1 |
| Halsall, D | 1 |
| Gurnell, M | 1 |
| Chrysis, D | 1 |
| Efthymiadou, A | 1 |
| Buchanan, C | 1 |
| Aylwin, S | 1 |
| Chatterjee, KK | 1 |
1 other study available for thyroxine and Apraxia of Gait
| Article | Year |
|---|---|
Resistance to thyroid hormone caused by a mutation in thyroid hormone receptor (TR)α1 and TRα2: clinical, biochemical, and genetic analyses of three related patients.
Topics: Adult; Alternative Splicing; Amino Acid Substitution; Family Health; Female; Gait Apraxia; Heterozyg | 2014 |