Page last updated: 2024-11-06

thyroxine and Apraxia of Gait

thyroxine has been researched along with Apraxia of Gait in 1 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"They had similar clinical (macrocephaly, broad faces, skin tags, motor dyspraxia, slow speech), biochemical (subnormal ratio of free thyroxine:free tri-iodothyronine [T3], low concentration of total reverse T3, high concentration of creatine kinase, mild anaemia), and radiological (thickened calvarium) features to patients with TRα1-mediated resistance to thyroid hormone, although our patients had a heterozygous mis-sense mutation (Ala263Val) in both TRα1 and TRα2 proteins."1.40Resistance to thyroid hormone caused by a mutation in thyroid hormone receptor (TR)α1 and TRα2: clinical, biochemical, and genetic analyses of three related patients. ( Agostini, M; Aylwin, S; Buchanan, C; Chatterjee, KK; Chrysis, D; Efthymiadou, A; Gurnell, M; Halsall, D; Lyons, G; Moran, C; Offiah, AC; Poole, K; Rajanayagam, O; Schoenmakers, E; Schoenmakers, N; Visser, WE, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moran, C1
Agostini, M1
Visser, WE1
Schoenmakers, E1
Schoenmakers, N1
Offiah, AC1
Poole, K1
Rajanayagam, O1
Lyons, G1
Halsall, D1
Gurnell, M1
Chrysis, D1
Efthymiadou, A1
Buchanan, C1
Aylwin, S1
Chatterjee, KK1

Other Studies

1 other study available for thyroxine and Apraxia of Gait

ArticleYear
Resistance to thyroid hormone caused by a mutation in thyroid hormone receptor (TR)α1 and TRα2: clinical, biochemical, and genetic analyses of three related patients.
    The lancet. Diabetes & endocrinology, 2014, Volume: 2, Issue:8

    Topics: Adult; Alternative Splicing; Amino Acid Substitution; Family Health; Female; Gait Apraxia; Heterozyg

2014